検索結果 37 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Iwamuro, Masaya| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-Ichi| Tanaka, Takehiro| Inokuchi, Toshihiro| Hiraoka, Sakiko| Otsuka, Motoyuki| |
| キーワード | Colonoscopy Esophagogastroduodenoscopy Graft-versus-host disease Hematopoietic stem cell transplantation Intestinal transplant-associated microangiopathy iTAM |
| 備考 | The version of record of this article, first published in BMC Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12876-024-03221-y| |
| 発行日 | 2024-04-22 |
| 出版物タイトル | BMC Gastroenterology |
| 巻 | 24巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 140 |
| ISSN | 1471-230X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024. |
| 論文のバージョン | publisher |
| PubMed ID | 38649868 |
| DOI | 10.1186/s12876-024-03221-y |
| Web of Science KeyUT | 001206319800003 |
| 関連URL | isVersionOf https://doi.org/10.1186/s12876-024-03221-y |
| JaLCDOI | 10.18926/AMO/65740 |
|---|---|
| フルテキストURL | 77_4_347.pdf |
| 著者 | Iwamuro, Masaya| Kondo, Takumi| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-ichi| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Maeda, Yoshinobu| Okada, Hiroyuki| |
| 抄録 | The feasibility of lymphocyte isolation and flow cytometry using a single endoscopic biopsy specimen from the gastrointestinal tract of patients who have undergone hematopoietic stem cell transplantation has not been investigated. We acquired 51 endoscopic biopsy specimens from the gastrointestinal tract of 35 patients. We divided the flow cytometry samples into two groups: group A, successful lymphocyte isolation (n=24), and group B, incomplete isolation (n=27). We compared the backgrounds of the samples between the groups to reveal crucial elements in the successful isolation of lymphocytes residing in the gastrointestinal tract. Comparison between the groups revealed lymphocyte isolation success rates differed between biopsy sites. Isolation was most successful in samples from the duodenum (8/9, 88.9%), followed by the ileum (4/8, 50.0%), large intestine (4/11, 36.4%), and stomach (8/23, 34.8%). Tacrolimus was used more frequently in group B (92.6%) than in group A (62.5%) (p=0.015). Logistic regression analysis revealed that isolation from the duodenum or ileum was a significant factor for successful isolation, while tacrolimus use was not statistically significant. In conclusion, the duodenum and ileum are more suitable sites than the stomach and colorectum for acquiring samples for flow cytometry. |
| キーワード | flow cytometry stem cell transplantation transplantation-associated microangiopathy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-08 |
| 巻 | 77巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 347 |
| 終了ページ | 357 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37635134 |
| Web of Science KeyUT | 001163659800002 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Otsuka, Yuki| Hagiya, Hideharu| Takahashi, Misa| Fukushima, Shinnosuke| Maeda, Ruri| Sunada, Naruhiko| Yamada, Haruto| Kishida, Masayuki| Fujita, Koji| Otsuka, Fumio| |
| 発行日 | 2023-01-12 |
| 出版物タイトル | Scientific Reports |
| 巻 | 13巻 |
| 号 | 1号 |
| 出版者 | Nature Research |
| 開始ページ | 647 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023 |
| 論文のバージョン | publisher |
| PubMed ID | 36635328 |
| DOI | 10.1038/s41598-022-27330-4 |
| Web of Science KeyUT | 000962604100025 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-022-27330-4 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yamamoto, Akira| Kambara, Yui| Fujiwara, Hideaki| |
| キーワード | oral microbiota GvHD dysbiosis allogeneic transplantation of hematopoietic cells prediction HSCT |
| 発行日 | 2023-03-09 |
| 出版物タイトル | Frontiers in Immunology |
| 巻 | 14巻 |
| 出版者 | Frontiers Media |
| 開始ページ | 1132983 |
| ISSN | 1664-3224 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Yamamoto, Kambara and Fujiwara. |
| 論文のバージョン | publisher |
| PubMed ID | 36969182 |
| DOI | 10.3389/fimmu.2023.1132983 |
| Web of Science KeyUT | 000954590800001 |
| 関連URL | isVersionOf https://doi.org/10.3389/fimmu.2023.1132983 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Matsusaka, Yohji| Chen, Xinyu| Arias-Loza, Paula| Werner, Rudolf A.| Nose, Naoko| Sasaki, Takanori| Rowe, Steven P.| Pomper, Martin G.| Lapa, Constantin| Higuchi, Takahiro| |
| 発行日 | 2022-06-21 |
| 出版物タイトル | Molecular Imaging |
| 巻 | 2022巻 |
| 出版者 | Hindawi Ltd. |
| 開始ページ | 4635171 |
| ISSN | 1536-0121 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 Yohji Matsusaka et al. |
| 論文のバージョン | publisher |
| PubMed ID | 35903251 |
| DOI | 10.1155/2022/4635171 |
| Web of Science KeyUT | 000890332200001 |
| 関連URL | isVersionOf https://doi.org/10.1155/2022/4635171 |
| JaLCDOI | 10.18926/AMO/63409 |
|---|---|
| フルテキストURL | 76_2_155.pdf |
| 著者 | Kimura, Jiro| Okabayashi, Takehiro| Sui, Kenta| Tabuchi, Motoyasu| Iwata, Jun| Hata, Yasuhiro| Iiyama, Tatsuo| Ono, Noriaki| |
| 抄録 | Small bowel metastasis from renal cell carcinoma (RCC) is rare, and its clinicopathological characteristics are unclear; thus, we revisited the concept of this tumor and reviewed its diagnostic and treatment modalities. We filtered MEDLINE searches of articles published in English between 1950 and 2019, and identified 100 patients who had undergone treatment, including 1 patient from our clinic. We extracted patient characteristics, treatment, and prognostic data, resulting in clinicopathological data on 100 patients (83 men, 17 women). Mean age was 63 years (range, 16-86 years). Tumor sites were duodenum, jejunum, ileum, and multiple sites in 30, 37, 25, and 7 patients, respectively. The 1-, 3-, and 5-year overall survival rates after diagnosis were 53.0%, 36.0%, and 36.0%. Curative resection patients showed 62.1% 5-year survival after surgery, vs. 27.5% in noncurative surgical management cases. Good prognoses can be expected if these tumors are identified early for complete removal. Surgery is the only curative option. To determine the best management strategy and improve prognostic accuracy, we continue to collect and analyze epidemiological and pathological data. Although this condition is rare, surgery should be considered if curative resection is expected. Prognosis after curative resection is not poor, but recurrence is not unlikely. |
| キーワード | renal cell carcinoma small bowel metastasis intestine tumor |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-04 |
| 巻 | 76巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 155 |
| 終了ページ | 165 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35503443 |
| Web of Science KeyUT | 000792374900007 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Nishimura, Midori Filiz| Nishimura, Yoshito| Nishikori, Asami| Yoshino, Tadashi| Sato, Yasuharu| |
| キーワード | primary gastrointestinal T-cell lymphoma enteropathy-associated T-cell lymphoma EATL monomorphic epitheliotropic intestinal T-cell lymphoma MEITL indolent T-cell lymphoproliferative disorder ITLPD-GI NK-cell enteropathy |
| 発行日 | 2021-11-18 |
| 出版物タイトル | Cancers |
| 巻 | 13巻 |
| 号 | 22号 |
| 出版者 | MDPI |
| 開始ページ | 5774 |
| ISSN | 2072-6694 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 34830926 |
| DOI | 10.3390/cancers13225774 |
| Web of Science KeyUT | 000724981100001 |
| 関連URL | isVersionOf https://doi.org/10.3390/cancers13225774 |
| JaLCDOI | 10.18926/AMO/62782 |
|---|---|
| フルテキストURL | 75_5_663.pdf |
| 著者 | Sadahira, Takuya| Maruyama, Yuki| Hiyama, Yoshiki| Kitano, Hiroyuki| Yamada, Hiroki| Goto, Takayuki| Kondo, Tsubasa| Shigemura, Katsumi| Mitsui, Yosuke| Iwata, Takehiro| Edamura, Kohei| Araki, Motoo| Watanabe, Masami| Takenaka, Tadasu| Teishima, Jun| Miyata, Yasuyoshi| Ishikawa, Kiyohito| Takaoka, Ei-Ichiro| Miyazaki, Jun| Takahashi, Satoshi| Masumori, Naoya| Kiyota, Hiroshi| Fujisawa, Masato| Yamamoto, Shingo| Sakuma, Takafumi| Kusumi, Norihiro| Ichikawa, Takaharu| Watanabe, Toyohiko| Nasu, Yoshitsugu| Tsugawa, Masaya| Nasu, Yasutomo| Wada, Koichiro| |
| 抄録 | The aim of this report is to introduce an on-going, multicenter, randomized controlled trial to evaluate whether tailored antimicrobial prophylaxis guided by rectal culture screening prevents acute bacterial prostatitis following transrectal prostate biopsy (TRPB). Patients will be randomized into an intervention or non-intervention group; tazobactam-piperacillin or levofloxacin will be prophylactically administered according to the results of rectal culture prior to TRPB in the intervention group whereas levofloxacin will be routinely given in the non-intervention group. The primary endpoint is the occurrence rate of acute bacterial prostatitis after TRPB. Recruitment begins in April, 2021 and the target total sample size is 5,100 participants. |
| キーワード | antibiotic prophylaxis selective culture media prostate biopsy fluoroquinolone-resistant extended- spectrum beta-lactamase |
| Amo Type | Clinical Study Protocol |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-10 |
| 巻 | 75巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 663 |
| 終了ページ | 667 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34703052 |
| Web of Science KeyUT | 000711568400007 |
| NAID | 120007166667 |
| JaLCDOI | 10.18926/AMO/62775 |
|---|---|
| フルテキストURL | 75_5_625.pdf |
| 著者 | Iwamuro, Masaya| Yamasaki, Yasushi| Tanaka, Takehiro| Asada, Noboru| Matsuoka, Ken-ichi| Hiraoka, Sakiko| Kawahara, Yoshiro| Okada, Hiroyuki| |
| 抄録 | A 77-year-old Japanese woman who had been treated for follicular lymphoma for 8 years developed abdominal pain and intra-abdominal lymphadenopathies. Colonoscopy revealed an elevated lesion in the rectum, which presented as two humps with erosions. A diagnosis of histologic transformation of follicular lymphoma to diffuse large B-cell lymphoma was made by endoscopic biopsy. This case underscores the importance of endoscopy examinations and biopsy of newly emerged gastrointestinal lesions for the prompt diagnosis of histologic transformation, since salvage chemotherapy must be initiated quickly in such cases. |
| キーワード | colorectal lymphoma follicular lymphoma diffuse large B-cell lymphoma histologic transformation |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-10 |
| 巻 | 75巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 625 |
| 終了ページ | 629 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34703045 |
| Web of Science KeyUT | 000711561300001 |
| NAID | 120007166675 |
| JaLCDOI | 10.18926/AMO/62767 |
|---|---|
| フルテキストURL | 75_5_549.pdf |
| 著者 | Isooka, Nami| Miyazaki, Ikuko| Asanuma, Masato| |
| 抄録 | Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. The loss of nigrostriatal dopaminergic neurons produces its characteristic motor symptoms, but PD patients also have non-motor symptoms such as constipation and orthostatic hypotension. The pathological hallmark of PD is the presence of α-synuclein-containing Lewy bodies and neurites in the brain. However, the PD pathology is observed in not only the central nervous system (CNS) but also in parts of the peripheral nervous system such as the enteric nervous system (ENS). Since constipation is a typical prodromal non-motor symptom in PD, often preceding motor symptoms by 10-20 years, it has been hypothesized that PD pathology propagates from the ENS to the CNS via the vagal nerve. Discovery of pharmacological and other methods to halt this progression of neurodegeneration in PD has the potential to improve millions of lives. Astrocytes protect neurons in the CNS by secretion of neurotrophic and antioxidative factors. Similarly, astrocyte-like enteric glial cells (EGCs) are known to secrete neuroprotective factors in the ENS. In this article, we summarize the neuroprotective function of astrocytes and EGCs and discuss therapeutic strategies for the prevention of neurodegeneration in PD targeting neurotrophic and antioxidative molecules in glial cells. |
| キーワード | Parkinson’s disease astrocyte enteric glial cell neurotrophic factor antioxidative molecule |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-10 |
| 巻 | 75巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 549 |
| 終了ページ | 556 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34703037 |
| Web of Science KeyUT | 000711561600001 |
| NAID | 120007166678 |
| JaLCDOI | 10.18926/AMO/60806 |
|---|---|
| フルテキストURL | 74_5_443.pdf |
| 著者 | Sekito, Takanori| Araki, Motoo| Hiraki, Takao| Uka, Mayu| Komaki, Toshiyuki| Matsui, Yusuke| Iguchi, Toshihiro| Katayama, Satoshi| Yoshinaga, Kasumi| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Kubota, Risa| Sadahira, Takuya| Nishimura, Shingo| Wada, Koichiro| Takamoto, Atsushi| Edamura, Kohei| Sako, Tomoko| Kobayashi, Yasuyuki| Watanabe, Toyohiko| Kanazawa, Susumu| Nasu, Yasutomo| |
| 抄録 | We report a 47-year-old Japanese female with 10 previous treatments for multiple bilateral renal cell carcinoma (RCC) associated with von Hippel-Lindau disease. The 14-mm right lower pole renal tumor was in contact with the right ureter. Laparoscopic cryoablation was performed to protect the ureter wrapped with gauze. Computed tomography (CT) monitoring was used to confirm the precise ≥ 6 mm ice-ball margin. There was no local progression at 6-months post-surgery. The serum creatinine has been stable. This is apparently the first report of combined laparoscopic and CT monitoring of an ice-ball formation and its margin during cryoablation for RCC. |
| キーワード | laparoscopic cryoablation multiple renal masses nephron-sparing surgery renal cell carcinoma von Hippel-Lindau disease |
| Amo Type | Case Report |
| 備考 | Fig. 1B is replaced on Dec. 23, 2020.| |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-10 |
| 巻 | 74巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 443 |
| 終了ページ | 448 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33106702 |
| Web of Science KeyUT | 000581970100011 |
| NAID | 120006892932 |
| JaLCDOI | 10.18926/AMO/60363 |
|---|---|
| フルテキストURL | 74_4_265.pdf |
| 著者 | Inokuchi, Toshihiro| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahar, Masahiro| Kawano, Seiji| Harada, Keita| Okada, Hiroyuki| Kato, Jun| |
| 抄録 | Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy. |
| キーワード | Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-08 |
| 巻 | 74巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 265 |
| 終了ページ | 274 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32843757 |
| Web of Science KeyUT | 000562508700001 |
| NAID | 120006880202 |
| JaLCDOI | 10.18926/AMO/55659 |
|---|---|
| フルテキストURL | 72_1_23.pdf |
| 著者 | Fujiia, Masayoshi| Takata, Katsuyoshi| Chuang, Shih-Sung| Miyata-Takata, Tomoko| Ando, Midori| Sato, Yasuharu| Yoshino, Tadashi| |
| 抄録 | The gastrointestinal (GI) tract is the most frequently involved site of extranodal non-Hodgkin lymphomas, and diffuse large B-cell lymphoma (DLBCL) is the most common subtype occurring in the GI tract. TNFAIP3 (A20) genetic alterations were reported to be involved in DLBCL’s pathogenesis and a portion of GI-DLBCL cases harbor this alteration. However, the frequency and clinicopathological relations focusing on small and large intestinal DLBCL are unclear. Here, we examined A20 deletion and protein expression and analyzed the clinicopathological features of 52 cases of primary intestinal DLBCL. The most frequently involved site was the ileocecal region (75%), followed by small bowel (13.5%) and large intestine. Immunohistochemically, the ileocecal cases expressed BCL6 (p=0.027) and MUM1 (p=0.0001) significantly more frequently than the small intestinal cases. Six of 47 cases (13%) had A20 heterozygous deletion, whereas all 6 heterozygously deleted cases had detectable A20 protein expression. In summary, A20 abnormality was less prevalent among intestinal DLBCLs with some discordancy between gene deletion and protein expression. Although the A20 alteration status did not affect any clinicopathological characteristics in this series, further studies exploring alterations of A20 and other NF-κB components in primary intestinal DLBCL are needed. |
| キーワード | primary intestinal diffuse large B-cell lymphoma cell of origin A20 TNFAIP3 heterozygous deletion |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2018-02 |
| 巻 | 72巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 23 |
| 終了ページ | 30 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 29463935 |
| タイトル（別表記） | Behçetʼs disease complicated by ileocecal and esophageal perforation |
|---|---|
| フルテキストURL | 128_27.pdf |
| 著者 | 九十九 悠太| 河本 和幸| 高木 弘誠| 陳 開| 松葉 優里| 長久 吉雄| 岡部 道雄| 白川 靖博| 伊藤 雅| 藤原 俊義| |
| 抄録 | A 36-year-old Japanese man known to have incomplete Behçet’s disease (oral aphthous ulcers, genital ulcers, skin lesions, and esophageal and ileocecal ulcers) was admitted to our hospital in January 2011 for abdominal pain. We administered corticosteroids and immunosuppressants. Two months later, we performed an ileocecal resection to control gastrointestinal bleeding from the ileocecal ulcers. High fever persisted after this surgery, and upper gastrointestinal endoscopy demonstrated ulcer penetration between the lower and abdominal esophagus. Eighteen days after the initial ileocecal resection, we performed a lower esophagus resection, gastric tube reconstruction and enterostomy, during which we confirmed a 5-mm-dia. perforated site at the posterior wall of the abdominal esophagus. Postoperative anastomotic leakage and empyema occurred, but they were relieved by thoracic drainage and empyema dissection. |
| キーワード | ベーチェット病（Behçet’s disease） 食道（esophagus） 回盲部（ileocecal） 穿孔（perforation） 手術（surgery） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2016-04-01 |
| 巻 | 128巻 |
| 号 | 1号 |
| 開始ページ | 27 |
| 終了ページ | 32 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.128.27 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2016 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.128.27 |
| NAID | 130005149603 |
| 著者 | 平井出 正三| |
|---|---|
| 発行日 | 1935-07-31 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 7号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 太田 康幸| |
|---|---|
| 発行日 | 1959-09-20 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 10-1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 奥村 一敏| |
|---|---|
| 発行日 | 1959-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 71巻 |
| 号 | 7-1号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/32420 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Itano, Satoshi| |
| 抄録 | Some cases of early gastric cancer are accompanied with complications of the upper gastro-intestinal tract. The characteristics of these complications were investigated, and the problems of diagnosis and treatment were discussed. Out of 297 cases of early gastric cancer, 18 cases were accompanied with complications of the upper gastro-intestinal tract, including 11 cases of bleeding, a case of perforation and 6 cases of pyloric stenosis. All 18 cases were of the macroscopically depressed type, and about 85 percent of the 297 early gastric cancer cases were of the depressed type. The depressed lesions were often accompanied by ulceration which was an important factor causing the complications, and the mechanism of which appeared to be the same as that of a benign ulcer. There are some cases of early gastric cancer which are discovered by their complications, and it would be more difficult to find an early gastric cancer lesion if there were a benign lesion at the same time. Therefore, it is necessary to take much care when diagnosing and treating cases which have such complications. An endoscopic examination before the operation is especially important, and a biopsy is indispensable. |
| キーワード | early gasric cancer complication bleeding perforation pyloric stenosis |
| Amo Type | Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 1983-10 |
| 巻 | 37巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 431 |
| 終了ページ | 440 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 6606297 |
| Web of Science KeyUT | A1983RN98400007 |
| JaLCDOI | 10.18926/AMO/31697 |
|---|---|
| フルテキストURL | fulltext.pdf |
| 著者 | Nakao, Atsunori| Tahara, Kazunori| Inoue, Seichiro| Tanaka, Noriaki| Kobayashi, Eiji| |
| 抄録 | Two kinds of surgical models of small intestinal transplantation (SITx) in rats, namely heterotopic (HIT) and orthotopic transplantion (OIT), have been reviewed. In OIT, the small intestine of the recipient is removed and the transplanted intestine replaces it in continuity. On the other hand, in the HIT model, the small intestinal grafts are rendered dysfunctional without alimentary tract continuity. Histological evidence showed that acute rejection appeared earlier in HIT as compared to OIT. Hyperplasia and hypertrophy of the muscularis externa produced in the chronic rejection process were more pronounced in HIT allografts. The HIT grafts showed severe mucosal atrophy due to the lack of intraluminal trophic factors, because oral feedings can stimulate tropic hormones for mucosal growth, and provide nutrients for enterocytes. Intestinal permeability was consistently higher after HIT than after OIT. The HIT grafts demonstrated less contractility and less response to chemical stimulation than did OIT grafts. The OIT models are advantageous in studies of intraluminal nutrients, and intestinal secretions in these models might modulate the intestinal immune status and possibly delay rejection. The superior intestinal barrier function and the delayed onset of rejection in OIT rats suggest that nutrients and other factors in the succus entericus are important for the maintenance of intestinal graft function. |
| キーワード | small intestinal transplantation rat experimental model orthotopic heterotopic |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2002-04 |
| 巻 | 56巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 69 |
| 終了ページ | 74 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 12002620 |
| Web of Science KeyUT | 000175176900002 |
| JaLCDOI | 10.18926/21105 |
|---|---|
| タイトル（別表記） | A case report of a family with Peutz-Jeghers syndrome |
| フルテキストURL | pitsr_054_025_033.pdf |
| 著者 | 入江 誠治| 原田 英雄| 川端 健二| 柴田 凡夫| |
| 抄録 | A 58-year-old female was admitted because of colicky abdominal pain. Physical examination revealed firm abdominal wall, increased bowel sounds and multiple pigmented macules on the lips, oral mucosa, soles and volar aspects of the fingers and toes. Hyperventilation and tetanic rigidity of the extremities were also noted. The symptoms were successfully treated by intravenous injection of butropium bromide and diazepam. Roentgenological and fiberscopic examination revealed multiple polyps in the stomach, small intestine and colon ; the small intestine was most heavily loaded with polyps. Biopsy specimen revealed only inflammatory changes. The patient had undergone a resectien of the terminal ileum with polyps 15 years previously because of ileo-ileal intussusception. Histological re-evaluation of the polyp showed an actively proliferating papillary adenoma. The characteristic history and gastrointestinal findings lead us to the examination of the family, which revealed that her father, son and grandson had similar pigmentation of the skin and polyps in the gastrointestinal tract. These characteristic findings and family history permitted us to make a diagnosis of Peutz-Jeghers syndrome. The diagnosis had been missed supposedly because of unawareness of the skin lesions and the lack of hamartoma-like findings in the polyp. The tetanic rigidity of the extremities was probably hyperventilation syndrome induced by severe abdominal pain. The patient has been followed up for possible recurrence of symptoms and a potential malignant change. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1984-03-25 |
| 巻 | 54巻 |
| 開始ページ | 25 |
| 終了ページ | 33 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002310995 |