検索結果 1586 件
| JaLCDOI | 10.18926/AMO/62232 |
|---|---|
| フルテキストURL | 75_3_363.pdf |
| 著者 | Tanioka, Nohito| Shimizu, Hiroko| Omori, Emiko| Takahashi, Toru| Yamaoka, Masakazu| Morimatsu, Hiroshi| |
| 抄録 | Hepatic oxidative stress plays an important role in the pathogenesis of several acute liver diseases, and free heme is thought to contribute to endotoxemia-induced acute liver injury. The heme oxygenase 1 (HO-1) gene is upregulated and the δ-aminolevulinate synthase (ALAS1) gene is downregulated in the rat liver following lipopolysaccharide (LPS) treatment. BTB and CNC homology 1 (Bach1) is a heme-responsive transcription factor that normally represses HO-1 expression. In this study, we evaluated the changes in HO-1, ALAS1, and Bach1 expression and nuclear Bach1 expression in rat livers following intravenous LPS administration (10 mg/kg body weight). LPS significantly upregulated HO-1 mRNA and downregulated ALAS1 mRNA in the rat livers, suggesting that hepatic free heme concentrations are increased after LPS treatment. Bach1 mRNA was strongly induced after LPS injection. In contrast, nuclear Bach1 was significantly but transiently decreased after LPS treatment. Rats were also administered hemin (50 mg/kg body weight) intravenously to elevate heme concentrations, which decreased nuclear Bach1 levels. Our results suggest that elevated hepatic free heme may be associated with a decline of nuclear Bach1, and induction of Bach1 mRNA may compensate for the decreased nuclear Bach1 after LPS treatment in the rat liver. |
| キーワード | heme oxygenase-1 BTB and CNC homology 1 heme, lipopolysaccharide liver injury |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 363 |
| 終了ページ | 372 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176941 |
| Web of Science KeyUT | 000667147700012 |
| NAID | 120007089829 |
| JaLCDOI | 10.18926/AMO/62230 |
|---|---|
| フルテキストURL | 75_3_351.pdf |
| 著者 | Mitamura, Katsuya| Norikane, Takashi| Yamamoto, Yuka| Ihara-Nishishita, Ayumi| Kobata, Takuya| Fujimoto, Kengo| Takami, Yasukage| Kudomi, Nobuyuki| Hoshikawa, Hiroshi| Nishiyama, Yoshihiro| |
| 抄録 | We assessed the role of 18F-FDG PET/CT texture indices for the differentiation of squamous cell carcinoma (SCC) and non-Hodgkin’s lymphoma (NHL) in the oropharynx. 18F-FDG PET/CT data for 27 patients with SCC and 25 patients with NHL in the oropharynx were investigated. The maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), total lesion glycolysis (TLG), and six texture indices (homogeneity, entropy, short-run emphasis, long-run emphasis, low gray-level zone emphasis [LGZE], and high graylevel zone emphasis [HGZE]) were derived from PET images. PET/CT parameters of the SCC patients were compared with those of the NHL patients. The diagnostic accuracy of the indices for differentiating SCC from NHL was calculated by a receiver operating characteristic curve analysis. 18F-FDG uptake in the oropharynx was observed in all of the patients. The SUVmax, MTV, and TLG did not differ significantly between the SCC and NHL groups, but two of the six texture indices (LGZE [p=0.004] and HGZE [p=0.03]) showed significant differences between the groups. LGZE was the best discriminative index for the differentiation of SCC and NHL (55.6% sensitivity, 88.0% specificity). The LGZE and HGZE texture indices derived from 18F-FDG PET/CT images may be useful in differentiating SCC and NHL in the oropharynx. |
| キーワード | 18F-FDG PET/CT oropharyngeal squamous cell carcinoma malignant lymphoma texture |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 351 |
| 終了ページ | 356 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176939 |
| Web of Science KeyUT | 000667147700010 |
| NAID | 120007089827 |
| JaLCDOI | 10.18926/AMO/62220 |
|---|---|
| フルテキストURL | 75_3_289.pdf |
| 著者 | Miyamoto, Masakazu| Osawa, Kazuhiro| Miyoshi, Toru| Mori, Atsushi| Yoshikawa, Masaki| Oka, Takefumi| Ichikawa, Keishi| Nakamura, Kazufumi| Ito, Hiroshi| |
| 抄録 | Early treatment with an oral β-blocker is recommended in patients with a ST-segment–elevation myocardial infarction (STEMI). In this multicenter study, we evaluated the effects of a continuous administration of landiolol, an ultrashort-acting β-blocker, before primary percutaneous coronary intervention (PCI) on myocardial salvage and its safety in STEMI patients. A total of 47 Japanese patients with anterior or lateral STEMI undergoing a primary PCI within 12 h of symptom onset were randomized to receive intravenous landiolol (started at 3 μg/min/kg dose and continued to a total of 50 mg; n=23) or not (control; n=24). Patients with Killip class III or more were excluded. The primary outcome was the myocardial salvage index on cardiac magnetic resonance imaging (MRI) performed 5-7 days after the PCI. Cardiac MRI was performed in 35 patients (74%). The myocardial salvage index in the landiolol group was significantly greater than that in the control group (44.4±14.6% vs. 31.7±18.9%, respectively; p=0.04). There were no significant differences in adverse events at 24 h between the landiolol and control groups. A continuous administration of landiolol before a primary PCI may increase the degree of myocardial salvage without additional hemodynamic adverse effects within the first 24 h after STEMI. |
| キーワード | myocardial infarction landiolol magnetic resonance imaging STEMI PCI |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 289 |
| 終了ページ | 297 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176932 |
| Web of Science KeyUT | 000667147700004 |
| NAID | 120007089835 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kuroda, Kosuke| Ishii, Kenzo| Mihara, Yuko| Kawanoue, Naoya| Wake, Hidenori| Mori, Shuji| Yoshida, Michihiro| Nishibori, Masahiro| Morimatsu, Hiroshi| |
| 発行日 | 2021-05-13 |
| 出版物タイトル | Scientific Reports |
| 巻 | 11巻 |
| 号 | 1号 |
| 出版者 | Nature Research |
| 開始ページ | 10223 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2021 |
| 論文のバージョン | publisher |
| PubMed ID | 33986340 |
| DOI | 10.1038/s41598-021-89555-z |
| NAID | 120007053368 |
| Web of Science KeyUT | 000656946100013 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-021-89555-z |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Omori, Toshinori| Tazawa, Hiroshi| Yamakawa, Yasuaki| Osaki, Shuhei| Hasei, Joe| Sugiu, Kazuhisa| Komatsubara, Tadashi| Fujiwara, Tomohiro| Yoshida, Aki| Kunisada, Toshiyuki| Urata, Yasuo| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi| |
| キーワード | Gastric yolk sac Tumor-like carcinoma Adenocarcinoma; Alpha-fetoprotein |
| 発行日 | 2021-04-22 |
| 出版物タイトル | PLoS ONE |
| 巻 | 16巻 |
| 号 | 4号 |
| 出版者 | Public Library Science |
| 開始ページ | e0250643 |
| ISSN | 1932-6203 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 Omori et al. |
| 論文のバージョン | publisher |
| PubMed ID | 33886686 |
| DOI | 10.1371/journal.pone.0250643 |
| NAID | 120007045007 |
| Web of Science KeyUT | 000644138300019 |
| 関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0250643 |
| フルテキストURL | K0006347_abstract_review.pdf K0006347_fulltext.pdf K0006347_summary.pdf |
|---|---|
| 著者 | 松前 洋| |
| 発行日 | 2021-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第6347号 |
| 学位授与年月日 | 2021-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| 著作権者 | © 2020 by the American Academy of Ophthalmology |
| フルテキストURL | fulltext.pdf Erratum.pdf |
|---|---|
| 著者 | Kataoka, Takahiro| Kanzaki, Norie| Sakoda, Akihiro| Shuto, Hina| Yano, Junki| Naoe, Shota| Tanaka, Hiroshi| Hanamoto, Katsumi| Terato, Hiroaki| Mitsunobu, Fumihiro| Yamaoka, Kiyonori| |
| キーワード | radon redox state oxidative stress antioxidative function principal component analysis |
| 発行日 | 2021-01-27 |
| 出版物タイトル | Journal of Radiation Research |
| 巻 | 62巻 |
| 号 | 3号 |
| 出版者 | Oxford Univ Press |
| 開始ページ | 390 |
| 終了ページ | 400 |
| ISSN | 0449-3060 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2021. |
| 論文のバージョン | publisher |
| PubMed ID | 33503655 |
| DOI | 10.1093/jrr/rraa129 |
| NAID | 120007042386 |
| Web of Science KeyUT | 000648970300003 |
| 関連URL | isVersionOf https://doi.org/10.1093/jrr/rraa129 |
| フルテキストURL | fulltext20210602-4.pdf |
|---|---|
| 著者 | Nakagawa, Masaki| Naruse, Hiroshi| |
| 備考 | This is an Accepted Manuscript of an article published by Springer This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00208-021-02196-5| |
| 発行日 | 2021-05-12 |
| 出版物タイトル | Mathematische Annalen |
| 巻 | 381巻 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 335 |
| 終了ページ | 361 |
| ISSN | 0025-5831 |
| NCID | AA00295941 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2021 |
| 論文のバージョン | author |
| DOI | 10.1007/s00208-021-02196-5 |
| Web of Science KeyUT | 000650111600002 |
| 関連URL | isVersionOf https://doi.org/10.1007/s00208-021-02196-5 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Miyamoto, Masakazu| Nishii, Nobuhiro| Morita, Hiroshi| Ito, Hiroshi| |
| キーワード | Idiopathic left ventricular tachycardia Double outlet right ventricle Fontan operation Purkinje potential Case report |
| 発行日 | 2020-09-07 |
| 出版物タイトル | European Heart Journal-Case Reports |
| 巻 | 4巻 |
| 号 | 5号 |
| 出版者 | Oxford Univ Press |
| ISSN | 2514-2119 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2020. |
| 論文のバージョン | publisher |
| PubMed ID | 33204969 |
| DOI | 10.1093/ehjcr/ytaa264 |
| NAID | 120007042390 |
| Web of Science KeyUT | 000646033200053 |
| 関連URL | isVersionOf https://doi.org/10.1093/ehjcr/ytaa264 |
| フルテキストURL | fulltext20210601-1.pdf |
|---|---|
| 著者 | Soga, Yoshihiko| Shirakawa, Yasuhiro| Fujiwara, Toshiyoshi| Ashiwa, Takako| Morimatsu, Hiroshi| |
| キーワード | perioperative management nutrition dental oral management |
| 備考 | This is a post-peer-review, pre-copyedit version of an article published in Current Oral Health Reports. The final authenticated version is available online at: http://dx.doi.org/10.1007/s40496-019-0217-3.| |
| 発行日 | 2019-04-15 |
| 出版物タイトル | Current Oral Health Reports |
| 巻 | 6巻 |
| 号 | 2号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 70 |
| 終了ページ | 75 |
| ISSN | 2196-3002 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| DOI | 10.1007/s40496-019-0217-3 |
| NAID | 120007042397 |
| 関連URL | isVersionOf https://doi.org/10.1007/s40496-019-0217-3 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Asano, Yosuke| Matsumoto, Yoshinori| La Rose, Rose, Jose| He, Fang| Katsuyama, Takayuki| Ziyi, Wang| Tsuji, Shigetomo| Kamioka, Hiroshi| Rottapel, Robert| Wada, Jun| |
| 発行日 | 2021-04-19 |
| 出版物タイトル | Scientific Reports |
| 巻 | 11巻 |
| 号 | 1号 |
| 出版者 | Nature Research |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2021 |
| 論文のバージョン | publisher |
| PubMed ID | 33875686 |
| DOI | 10.1038/s41598-021-87716-8 |
| NAID | 120007039923 |
| Web of Science KeyUT | 000642583500018 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-021-87716-8 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kuroe, Yasutoshi| Mihara, Yuko| Okahara, Shuji| Ishii, Kenzo| Kanazawa, Tomoyuki| Morimatsu, Hiroshi| |
| キーワード | Integrated pulmonary index Respiratory compromise Post‐anesthesia care unit |
| 発行日 | 2021-04-21 |
| 出版物タイトル | BMC Anesthesiology |
| 巻 | 21巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 123 |
| ISSN | 1471-2253 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s). 2021 |
| 論文のバージョン | publisher |
| PubMed ID | 33882856 |
| DOI | 10.1186/s12871-021-01338-1 |
| NAID | 120007037372 |
| Web of Science KeyUT | 000643881600003 |
| 関連URL | isVersionOf https://doi.org/10.1186/s12871-021-01338-1 |
| JaLCDOI | 10.18926/ESR/61959 |
|---|---|
| タイトル（別表記） | Estimation of displacement waveforms by baseline correction of near-fault acceleration records of the 2016 Kumamoto earthquake with median filter |
| フルテキストURL | esr_027_039_050.pdf |
| 著者 | 渡邉 禎貢| 小松 正直| 竹中 博士| |
| 抄録 | The 2016 Kumamoto earthquake sequence occurred on April 14 (MJMA 6.5) and April 16 (MJMA 7.3). Seismic intensity of 7 on the Japan Meteorological Agency (JMA) scale was observed in Mashiki Town, Kumamoto Prefecture for the both events and in Nishihara Village, Kumamoto Prefecture for the April-16 event. We estimate the displacement waveforms from these acceleration records. Since the acceleration seismograms include the long-period noise due to tilting of the ground and instrumental effects, the baseline corrections are required to derive the accurate velocity and displacement waveforms. We apply a median filter to the velocity waveforms to identify the linear trends on them due to the steplike noise on the acceleration records, and determine the time at which baseline shifts take place and the step value of each shift for the baseline correction through trial and error. Our baseline correction can successfully reconstruct the velocity and displacement waveforms from the acceleration records. The displacement waveforms show the static components consistent with the geodetic data. |
| キーワード | 2016 Kumamoto earthquake baseline correction median filter displacement |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2021-03-31 |
| 巻 | 27巻 |
| 号 | 1号 |
| 開始ページ | 39 |
| 終了ページ | 50 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2021 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120007037380 |
| JaLCDOI | 10.18926/ESR/61956 |
|---|---|
| タイトル（別表記） | Synthetic nearfield seismograms at a subsurface position in a horizontally layered half-space |
| フルテキストURL | esr_027_029_038.pdf |
| 著者 | 竹中 博士| 渡邉 禎貢| |
| 抄録 | We extend the computational code of Takenaka and Sasatani (2000) for synthetic nearfield seismograms for horizontally layered elastic media, based on the reflection/transmission matrices and the discrete wavenumber summation method, to calculate seismic motion and its spatial derivatives at a subsurface position in the attenuative media. In this paper we describe the theory of this extension and show some numerical examples to verify the extended code. |
| キーワード | synthetic seismogram reflectivity method layered half-space |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2021-03-31 |
| 巻 | 27巻 |
| 号 | 1号 |
| 開始ページ | 29 |
| 終了ページ | 38 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2021 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120007037377 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yamamoto, Maho| Kondo, Rina| Hozumi, Haruka| Doi, Seita| Denda, Miwako| Magari, Masaki| Kanayama, Naoki| Hatano, Naoya| Morishita, Ryo| Tokumitsu, Hiroshi| |
| キーワード | S100 protein HMG20A protein-protein interaction Ca2+-signal transduction genome-wide screening |
| 発行日 | 2021-03-30 |
| 出版物タイトル | Biomolecules |
| 巻 | 11巻 |
| 号 | 4号 |
| 出版者 | MDPI |
| 開始ページ | 510 |
| ISSN | 2218-273X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | publisher |
| PubMed ID | 33808200 |
| DOI | 10.3390/biom11040510 |
| NAID | 120007037385 |
| Web of Science KeyUT | 000642769800001 |
| 関連URL | isVersionOf https://doi.org/10.3390/biom11040510 |
| JaLCDOI | 10.18926/AMO/61908 |
|---|---|
| フルテキストURL | 75_2_243.pdf |
| 著者 | Tomita, Yusuke| Shimazu, Yosuke| Kawakami, Masato| Matsumoto, Hiroshi| Fujii, Kentaro| Kameda, Masahiro| Yasuhara, Takao| Suruga, Yasuki| Ota, Tomoyuki| Kimata, Yoshihiro| Kurozumi, Kazuhiko| Date, Isao| |
| 抄録 | Ventriculitis is a rare, serious complication of neurosurgery. A 59-year-old man who had undergone a craniotomy for a paranasal adenocarcinoma, developed a right frontal cystic lesion. We performed a bifrontal craniotomy to remove the lesion. The dura was repaired with non-vascularized free fascia lata in watertight fashion. Ventriculitis occurred 3 days postoperatively. Ventricular drainage, craniectomy, and endoscopic irrigation were undertaken to remove an abscess. The dura and the resection cavity were reconstructed using a vascularized anterolateral thigh adipofascial flap. His symptoms disappeared, indicating that endoscopic irrigation and reconstruction can effectively address ventriculitis even in patients in critical clinical condition. |
| キーワード | ventriculitis surgical site infection intraventricular antimicrobial therapy anterior skull base surgery |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-04 |
| 巻 | 75巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 243 |
| 終了ページ | 248 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33953433 |
| NAID | 120007029879 |
| JaLCDOI | 10.18926/AMO/61902 |
|---|---|
| フルテキストURL | 75_2_205.pdf |
| 著者 | Hoshijima, Mitsuhiro| Kawanabe, Noriaki| Iida, Seiji| Yamashiro, Takashi| Kamioka, Hiroshi| |
| 抄録 | We herein report the case of a 19-year-old female with a transverse discrepancy, skeletal Class II malocclusion, severe crowding with concerns of classic-type Ehlers-Danlos syndrome (EDS), aesthetics problems and functional problems. The main characteristics of classic EDS are loose-jointedness and fragile, easily bruised skin that heals with peculiar “cigarette-paper” scars. The anteroposterior and transverse skeletal discrepancies can generally be resolved by maxilla repositioning and mandibular advancement surgery following pre-surgical orthodontic treatment. However, this patient was treated with orthodontic camouflage but not orthognathic surgery because of the risks of skin bruising, poor healing and a temporomandibular disorder. A satisfactory dental appearance and occlusion were achieved after camouflage treatment with orthodontic anchor screws and the use of Class II elastics, including the preservation of the stomatognathic functions. Acceptable occlusion and dentition were maintained after a two-year retention period. This treatment strategy of orthodontic camouflage using temporary anchorage, such as anchor screws and Class II elastics, may be a viable treatment option for skeletal malocclusion patients with EDS. |
| キーワード | asymmetry Class II camouflage orthodontic anchor screw Ehlers-Danlos syndrome |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-04 |
| 巻 | 75巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 205 |
| 終了ページ | 212 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33953427 |
| NAID | 120007029885 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Ichikawa, Keishi| Miyoshi, Toru| Osawa, Kazuhiro| Miki, Takashi| Ito, Hiroshi| |
| キーワード | malondialdehyde low-density lipoprotein high-risk plaque coronary computed tomography angiography statin |
| 発行日 | 2021-04-02 |
| 出版物タイトル | Journal of Clinical Medicine |
| 巻 | 10巻 |
| 号 | 7号 |
| 出版者 | MDPI |
| 開始ページ | 1480 |
| ISSN | 2077-0383 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/jcm10071480 |
| NAID | 120007029901 |
| Web of Science KeyUT | 000638623700001 |
| 関連URL | isVersionOf https://doi.org/10.3390/jcm10071480 |
| JaLCDOI | 10.18926/AMO/61877 |
|---|---|
| フルテキストURL | 75_2_115.pdf |
| 著者 | Hitomi, Nishizaki| Yoshinari, Morimoto| Yamada, Shin-ichi| Kurita, Hiroshi| Tanaka, Akira| Yamaguchi, Akira| Miyata, Masaru| Yoshikawa, Hiromasa | Yanamoto, Souichi| Imai, Yutaka| |
| 抄録 | The aim of this study was to investigate the awareness and experience, among dental practitioners, of adverse events resulting from dental treatment of patients undergoing therapy with drugs that affect the immune system [angiogenesis inhibitors, biological agents, immunosuppressants, and disease-modifying anti-rheumatic drugs (DMARDs)]. For this purpose, a nationwide questionnaire survey was conducted. Questionnaires were sent to 2,050 dentists, of which 206 (10.1%) were completed and returned. The results showed that most dentists were aware of complications associated with dental treatment of patients treated with drugs that affect the immune system, and about half had actually experienced such complications. Delayed wound healing, osteonecrosis of the jaw (ONJ), and postoperative infections were reported. Whereas approximately 50% of dentists did not discontinue the drugs during dental treatment, about 18% did. During temporary drug discontinuation, some patients experienced aggravation of the primary disease, such as worsening of rheumatism, growth of tumors, and rejection reactions of transplanted organs. As for medical cooperation, only less than half of the dentists were asked for oral hygiene management by a physician prior to starting the drug treatment. Prospective studies are needed because evidence for dental treatments in patients treated with these drugs remains limited. |
| キーワード | angiogenesis inhibitor biological agent disease-modifying antirheumatic drug (DMARD) immunosuppressant medication-related osteonecrosis of the jaw (MRONJ) |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-04 |
| 巻 | 75巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 115 |
| 終了ページ | 123 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33953417 |
| NAID | 120007029906 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Asada, Saori| Nishii, Nobuhiro| Shinya, Takayoshi| Miyoshi, Akihito| Morimoto, Yoshimasa| Miyamoto, Masakazu| Nakagawa, Koji| Nakamura, Kazufumi| Morita, Hiroshi| Ito, Hiroshi| |
| 発行日 | 2021-03-04 |
| 出版物タイトル | PLoS One |
| 巻 | 16巻 |
| 号 | 3号 |
| 出版者 | Public Library of Science |
| 開始ページ | e0245502 |
| ISSN | 1932-6203 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 Asada et al. |
| 論文のバージョン | publisher |
| PubMed ID | 33661956 |
| DOI | 10.1371/journal.pone.0245502 |
| NAID | 120007019113 |
| Web of Science KeyUT | 000626604100103 |
| 関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0245502 |