検索結果 - 岡山大学学術成果リポジトリ

Sleep Duration and Overweight among Elementary Schoolchildren:A Population-based Study in Japan

JaLCDOI	10.18926/AMO/48259
フルテキストURL	66_2_93.pdf.pdf
著者	Ochiai, Hirotaka\| Shirasawa, Takako\| Shimada, Naoki\| Ohtsu, Tadahiro\| Nishimura, Rimei\| Morimoto, Aya\| Hoshino, Hiromi\| Tajima, Naoko\| Kokaze, Akatsuki\|
抄録	Although a number of studies have investigated the relationship of sleep duration to overweight and obesity, studies conducted among population-based elementary schoolchildren have been limited in Japan. The aim of the present study was to investigate the relationship between sleep duration and overweight among elementary schoolchildren in Japan. The study subjects were all fourth-grade schoolchildren (9 or 10 years of age) in Ina-town, Saitama Prefecture, Japan from 1999 to 2008. Information concerning each subjectʼs sex, age, and lifestyle was obtained using a self-administered questionnaire, while measurements of his or her height and weight were carried out. Childhood overweight was determined according to the definition established by the International Obesity Task Force. Data from 3,433 children were analyzed. In logistic regression analysis, a statistically significant dose-response relationship was observed between sleep duration and overweight among boys (p for trend＝0.014) but not among girls (p for trend＝0.149). Short sleep duration was associated with childhood overweight, and the sex difference in the association was observed. These findings suggested that it is important to consider sleep duration as part of any program to prevent overweight among elementary schoolchildren, especially among boys.
キーワード	sleep overweight schoolchildren Japan
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2012-04
巻	66巻
号	2号
出版者	Okayama University Medical School
開始ページ	93
終了ページ	99
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	22525467
Web of Science KeyUT	000303175300002

Ataxia-Telangiectasia Mutated and the Mre11-Rad50-NBS1 Complex:Promising Targets for Radiosensitization

JaLCDOI	10.18926/AMO/48258
フルテキストURL	66_2_83.pdf.pdf
著者	Kuroda, Shinji\| Urata, Yasuo\| Fujiwara, Toshiyoshi\|
抄録	Radiotherapy plays a central part in cancer treatment, and use of radiosensitizing agents can greatly enhance this modality. Although studies have shown that several chemotherapeutic agents have the potential to increase the radiosensitivity of tumor cells, investigators have also studied a number of molecularly targeted agents as radiosensitizers in clinical trials based on reasonably promising preclinical data. Recent intense research into the DNA damage-signaling pathway revealed that ataxia-telangiectasia mutated (ATM) and the Mre11-Rad50-NBS1 (MRN) complex play central roles in DNA repair and cell cycle checkpoints and that these molecules are promising targets for radiosensitization. Researchers recently developed three ATM inhibitors (KU-55933, CGK733, and CP466722) and an MRN complex inhibitor (mirin) and showed that they have great potential as radiosensitizers of tumors in preclinical studies. Additionally, we showed that a telomerase-dependent oncolytic adenovirus that we developed (OBP-301 [telomelysin]) produces profound radiosensitizing effects by inhibiting the MRN complex via the adenoviral E1B55kDa protein. A recent Phase I trial in the United States determined that telomelysin was safe and well tolerated in humans, and this agent is about to be tested in combination with radiotherapy in a clinical trial based on intriguing preclinical data demonstrating that telomelysin and ionizing radiation can potentiate each other. In this review, we highlight the great potential of ATM and MRN complex inhibitors, including telomelysin, as radiosensitizing agents.
キーワード	ATM (ataxia-telangiectasia mutated) MRN (Mre11-Rad50-NBS1) complex radiosensitization adenovirus E1B55kDa
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2012-04
巻	66巻
号	2号
出版者	Okayama University Medical School
開始ページ	83
終了ページ	92
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	22525466
Web of Science KeyUT	000303175300001

裏表紙・英文目次

著者	岡山大学教師教育開発センター\|
発行日	2012-03-19
出版物タイトル	岡山大学教師教育開発センター紀要
巻	2巻
資料タイプ	その他

裏表紙・英文目次

著者	岡山大学大学院教育学研究科\|
発行日	2012-02-25
出版物タイトル	岡山大学大学院教育学研究科研究集録
巻	149巻
資料タイプ	その他

Universal Factorization Equalities for Quaternion Matrices and Their Applications

著者	Tian, Yongge\|
発行日	1999-01
出版物タイトル	Mathematical Journal of Okayama University
巻	41巻
号	1号
資料タイプ	学術雑誌論文
JaLCDOI	10.18926/mjou/48176

Semi-Convergence of Filters and Nets

著者	Latif, R. M.\|
発行日	1999-01
出版物タイトル	Mathematical Journal of Okayama University
巻	41巻
号	1号
資料タイプ	学術雑誌論文
JaLCDOI	10.18926/mjou/48175

Irreducibilities of the Induced Characters of Cyclic p-Groups

著者	Sekiguchi, Katsusuke\|
発行日	1999-01
出版物タイトル	Mathematical Journal of Okayama University
巻	41巻
号	1号
資料タイプ	学術雑誌論文
JaLCDOI	10.18926/mjou/48174

A Generalization of the Dade's Theorem on Localization of Injective Modules

著者	Hirata, Kazuhiko\| Syu, U\|
発行日	1999-01
出版物タイトル	Mathematical Journal of Okayama University
巻	41巻
号	1号
資料タイプ	学術雑誌論文
JaLCDOI	10.18926/mjou/48173

Quantification of the orientations of pyrrolidine-based oxypeptide nucleic acid–DNA hybrid duplexes

著者	Kitamatsu, Mizuki\| Sisido, Masahiko\|
発行日	2011-04-28
出版物タイトル	MedChemComm
巻	2巻
号	7号
資料タイプ	学術雑誌論文

裏表紙・英文目次

著者	岡山大学法学会\|
発行日	2012-03-21
出版物タイトル	岡山大學法學會雜誌
巻	61巻
号	4号
資料タイプ	その他

Optimal Computation of 3-D Similarity: Gauss-Newton vs.Gauss-Helmert

JaLCDOI	10.18926/48127
フルテキストURL	mfe_046_021_033.pdf
著者	Kanatani, Kenichi\| Niitsuma, Hirotaka\|
抄録	Because 3-D data are acquired using 3-D sensing such as stereo vision and laser range finders, they have inhomogeneous and anisotropic noise. This paper studies optimal computation of the similarity (rotation, translation, and scale change) of such 3-D data. We first point out that the Gauss-Newton and the Gauss-Helmert methods, regarded as different techniques, have similar structures. We then combine them to define what we call the modified Gauss-Helmert method and do stereo vision simulation to show that it is superior to either of the two in convergence performance. Finally, we show an application to real GPS geodetic data and point out that the widely used homogeneous and isotropic noise model is insufficient and that GPS geodetic data are prone to numerical problems.
出版物タイトル	Memoirs of the Faculty of Engineering, Okayama University
発行日	2012-01
巻	46巻
開始ページ	21
終了ページ	33
ISSN	1349-6115
言語	英語
著作権者	Copyright © by the authors
論文のバージョン	publisher
NAID	80022451622

Calibration of Ultra-Wide Fisheye Lens Cameras by Eigenvalue Minimization

JaLCDOI	10.18926/48126
フルテキストURL	mfe_046_010_020.pdf
著者	Kanatani, Kenichi\|
抄録	We present a new technique for calibrating ultra-wide fisheye lens cameras by imposing the constraint that collinear points be rectified to be collinear, parallel lines to be parallel, and orthogonal lines to be orthogonal. Exploiting the fact that line fitting reduces to an eigenvalue problem, we do a rigorous perturbation analysis to obtain a Levenberg-Marquardt procedure for the optimization. Doing experiments, we point out that spurious solutions exist if collinearity and parallelism alone are imposed. Our technique has many desirable properties. For example, no metric information is required about the reference pattern or the camera position, and separate stripe patterns can be displayed on a video screen to generate a virtual grid, eliminating the grid point extraction processing.
出版物タイトル	Memoirs of the Faculty of Engineering, Okayama University
発行日	2012-01
巻	46巻
開始ページ	10
終了ページ	20
ISSN	1349-6115
言語	英語
著作権者	Copyright © by the authors
論文のバージョン	publisher
NAID	80022451621

Optimal Computation of 3-D Similarity from Space Data with Inhomogeneous Noise Distributions

JaLCDOI	10.18926/48125
フルテキストURL	mfe_046_001_009.pdf
著者	Kanatani, Kenichi\| Niitsuma, Hirotaka\|
抄録	We optimally estimate the similarity (rotation, translation, and scale change) between two sets of 3-D data in the presence of inhomogeneous and anisotropic noise. Adopting the Lie algebra representation of the 3-D rotational change, we derive the Levenberg-Marquardt procedure for simultaneously optimizing the rotation, the translation, and the scale change. We test the performance of our method using simulated stereo data and real GPS geodetic sensing data. We conclude that the conventional method assuming homogeneous and isotropic noise is insufficient and that our simultaneous optimization scheme can produce an accurate solution.
出版物タイトル	Memoirs of the Faculty of Engineering, Okayama University
発行日	2012-01
巻	46巻
開始ページ	1
終了ページ	9
ISSN	1349-6115
言語	英語
著作権者	Copyright © by the authors
論文のバージョン	publisher
NAID	80022451620

Contents

著者	Faculty of Engineering, Okayama University\|
発行日	2012-01
出版物タイトル	Memoirs of the Faculty of Engineering, Okayama University
巻	46巻
資料タイプ	その他

Promotion of IL-4- and IL-5-dependent differentiation of anti-μ-primed B cells by ascorbic acid 2-glucoside

著者	Ichiyama, Kenji\| Mitsuzumi, Hitoshi\| Zhong, Ming\| Tai, Akihiro\| Tsuchioka, Akihiro\| Kawai, Saeko\| Yamamoto, Itaru\| Gohda, Eiichi\|
発行日	2009-02-21
出版物タイトル	Immunology Letters
巻	122巻
号	2号
資料タイプ	学術雑誌論文

Induction of hepatocyte growth factor production in human dermal fibroblasts and their proliferation by the extract of bitter melon pulp

著者	Ono, Takehiro\| Tsuji, Tomoe\| Sakai, Miho\| Yukizaki, Chizuko\| Ino, Hisatoshi\| Akagi, Isao\| Hiramatsu, Kaori\| Matsumoto, Yohsuke\| Sugiura, Yoshihiro\| Uto, Hirofumi\| Tsubouchi, Hirohito\| Gohda, Eiichi\|
発行日	2009-04
出版物タイトル	Cytokine
巻	46巻
号	1号
資料タイプ	学術雑誌論文

Electrochemical generation of silver acetylides from terminal alkynes with a Ag anode and integration into sequential Pd-catalysed coupling with arylboronic acids

著者	Mitsudo, Koichi\| Shiraga, Takuya\| Mizukawa, Jun-ichi\| Suga, Seiji\| Tanaka, Hideo\|
発行日	2010
出版物タイトル	Chemical Communications
巻	46巻
号	48号
資料タイプ	学術雑誌論文

Studies on the Synthesis of DMAP Derivatives by Diastereoselective Ugi Reactions

著者	Mandai, Hiroki\| Irie, Shunsuke\| Mitsudo, Koichi\| Suga, Seiji\|
発行日	2011-10-20
出版物タイトル	Molecules
巻	16巻
号	10号
資料タイプ	学術雑誌論文

裏表紙・英文目次

著者	岡山大学法学会\|
発行日	2012-02-28
出版物タイトル	岡山大學法學會雜誌
巻	61巻
号	3号
資料タイプ	その他

Improvement in sulfur desorption of NOX storage and reduction catalysts using a Ba–Ti composite oxide

著者	Tanaka, Toshiyuki\| Tajima, Ichirou\| Kato, Yuichi\| Nishihara, Yasushi\| Shinjoh, Hirofumi\|
発行日	2011-02-22
出版物タイトル	Applied Catalysis B: Environmental
巻	102巻
号	3-4号
資料タイプ	学術雑誌論文