検索結果 - 岡山大学学術成果リポジトリ

Factors Affecting the Absorption of Midazolam to the Extracorporeal Membrane Oxygenation Circuit

JaLCDOI	10.18926/AMO/56645
フルテキストURL	73_2_101.pdf
著者	Iida, Atsuyoshi\| Naito, Hiromichi\| Yorifuji, Takashi\| Zamami, Yoshito\| Yamada, Akane\| Koga, Tadashi\| Imai, Toru\| Sendo, Toshiaki\| Nakao, Atsunori\| Ichiba, Shingo\|
抄録	Sedatives are administered during extracorporeal membrane oxygenation (ECMO) therapy to ensure patient safety, reduce the metabolic rate and correct the oxygen supply-demand balance. However, the concentrations of sedatives can be decreased due to absorption into the circuit. This study examined factors affecting the absorption of a commonly used sedative, midazolam (MDZ). Using multiple ex vivo simulation models, three factors that may influence MDZ levels in the ECMO circuit were examined: polyvinyl chloride (PVC) tubing in the circuit, use of a membrane oxygenator in the circuit, and heparin coating of the circuit. We also assessed changes in drug concentration when MDZ was re-injected in a circuit. The MDZ level decreased to approximately 60% of the initial concentration in simulated circuits within the first 30 minutes. The strongest factor in this phenomenon was contact with the PVC tubing. Membrane oxygenator use tended to increase MDZ loss, whereas heparin circuit coating had no influence on MDZ absorption. Similar results were obtained when a second dose of MDZ was injected to the second-use circuits.
キーワード	sedatives ECMO polyvinyl chloride pharmacokinetics pharmacodynamics
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-04
巻	73巻
号	2号
出版者	Okayama University Medical School
開始ページ	101
終了ページ	107
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31015744

A prospective randomized trial comparing the clinical effectiveness and biocompatibility of heparin-coated circuits and PMEA-coated circuits in pediatric cardiopulmonary bypass

フルテキストURL	K0005299_other2.pdf
著者	Itoh, Hideshi\| Ichiba, Shing\| Ujike, Yoshihito\| Douguchi, Takuma\| Kasahara, Shingo\| Arai, Sadahiko\| Sano, Shunji\|
キーワード	PMEA coating cardiopulmonary bypass heparin coating pediatric transient leukopenia
備考	学位審査副論文\|
発行日	2016-04
出版物タイトル	Perfusion
巻	31巻
号	3号
出版者	Sage
開始ページ	247
終了ページ	254
ISSN	0267-6591
NCID	AA10674287
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja
論文のバージョン	author
PubMed ID	26228276
DOI	10.1177/0267659115598217
Web of Science KeyUT	000373410300010
関連URL	https://doi.org/10.1177/0267659115598217 http://ousar.lib.okayama-u.ac.jp/54282

The peptidergic control circuit for neuroendocrine dynamics in rats

フルテキストURL	K0005542_abstract_review.pdf K0005542_fulltext.pdf
著者	佐藤慧太\|
発行日	2017-03-24
資料タイプ	学位論文
学位授与番号	甲第5542号
学位授与年月日	2017-03-24
学位・専攻分野	博士（理学）
授与大学	岡山大学
言語	英語

Cryptochrome-dependent and -independent circadian entrainment circuits in Drosophila.

著者	Yoshii, Taishi\| Hermann-Luibl, Christiane\| Kistenpfennig, Christa\| Schmid, Benjamin\| Tomioka, Kenji\| Helfrich-Förster, Charlotte\|
発行日	2015-04-15
出版物タイトル	The Journal of neuroscience
巻	35巻
号	15号
資料タイプ	学術雑誌論文

Directed Differentiation of Patient-Specific Induced Pluripotent Stem Cells Identifies the Transcriptional Repression and Epigenetic Modification of NKX2-5, HAND1, and NOTCH1 in Hypoplastic Left Heart Syndrome

著者	Kobayashi, Junko\| Yoshida, Masashi\| Tarui, Suguru\| Hirata, Masataka\| Nagai, Yusuke\| Kasahara, Shingo\| Naruse, Keiji\| Ito, Hiroshi\| Sano, Shunji\| Oh, Hidemasa\|
発行日	2014-07-22
出版物タイトル	PLoS ONE
巻	9巻
号	7号
資料タイプ	学術雑誌論文

光トポグラフィーでみられる酸素化ヘモグロビン量の低周波変動の発生源に関する研究

タイトル（別表記）	The origin of infra-slow oscillations of oxygenated hemoglobin observed in functional near-infrared spectroscopy
フルテキストURL	126_117.pdf
著者	所司睦文\| 上野浩司\| 久保正子\| 小田真珠子\| 平田直也\| 武本梨佳\| 衣笠和孜\| 岡本基\|
抄録	There is increasing interest in the intrinsic activity of the resting brain, especially the activity slower than 0.1Hz (i.e., low-frequency oscillations, or LFOs). To investigate the origin of LFOs observed in functional near-infrared spectroscopy (fNIRS), we recorded multichannel fNIRS and electroencephalography (EEG) from the frontal cortex of 11 healthy young volunteers in the resting state. Electrocardiography (ECG), electro-oculography and respiration were also measured. Synchronous oscillations of oxy-hemoglobin (oxy-Hb) around 1.0Hz were detected in all fNIRS channels, and their frequency was consistent with a peak frequency of ECG, suggesting the changes of cerebral blood flow due to heart beats. In addition, oxy-Hb oscillations around 0.1Hz (i.e., LFOs) appeared in the fNIRS. The channels where LFOs appeared differed among the subjects, and the LFOs appeared or disappeared even in the same fNIRS channels. The appearance of LFOs in fNIRS channels was significantly higher when the LFOs appeared on the EEG in the adjacent EEG electrodes compared to when LFOs did not appear on EEG. The amplitude and coherence (synchronicity) of the LFOs were increased by changing the subjects' position from dorsal to the sitting position in both fNIRS and EEG, and the coherence in particular was increased in the homologous fNIRS channels on the bilateral hemispheres. These results suggest that LFOs of oxy-Hb couple with resting-state EEG activity.
キーワード	fNIRS EEG LFOs コヒーレンス解析（Coherence analysis）連続ウェーブレット解析（continuous wavelet transforms）
出版物タイトル	岡山医学会雑誌
発行日	2014-08-01
巻	126巻
号	2号
開始ページ	117
終了ページ	126
ISSN	0030-1558
言語	日本語
著作権者	Copyright (c) 2014 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.126.117
NAID	130004685262

Hox 遺伝子と聴覚回路の発生

著者	成田裕一\| Kajari Karmakar\| Sébastien Ducret\| Filippo M. Rijli\|
発行日	2014-04
出版物タイトル	岡山実験動物研究会報
巻	30巻
資料タイプ	その他

GBR12909の情動行動への影響：脳内自己刺激行動の Runway法を用いた動機付け行動と，抗うつ様行動および依存様行動の区別

著者	江角悟\| 相良英憲\| 中本秋彦\| 河崎陽一\| 五味田裕\| 千堂年昭\|
発行日	2013-12-02
出版物タイトル	岡山医学会雑誌
巻	125巻
号	3号
資料タイプ	学術雑誌論文

Aerial-Earth Circuitの生物に及ぼす影響に就て

著者	板野新夫\|
発行日	1935-05-05
出版物タイトル	農学研究
巻	24巻
資料タイプ	紀要論文

Investigation on the Influence of Aerial-Earth Circuit on the Biological Activities. III. Mechanism of the influence on Azotobacter chroococcum as to its electrophoresis.*

著者	Itano, Arao\|
発行日	1934-05-09
出版物タイトル	Berichte des Ohara Instituts für landwirtschaftliche Forschungen
巻	6巻
号	2号
資料タイプ	紀要論文

Investigation on the Influence of Aerial-Earth Circuit on the Biological Activities. 1. Influence on Azotobacter chroococcum.1) II. Mechanism of the Influence on Azotobacter chroococcum as to its Potential.2)

著者	Itano, Arao\|
発行日	1933-08-20
出版物タイトル	Berichte des Ohara Instituts für landwirtschaftliche Forschungen
巻	6巻
号	1号
資料タイプ	紀要論文

Electroconductive π-Junction Au Nanoparticles

著者	Kanehara, Masayuki\| Takeya, Jun\| Uemura, Takafumi\| Murata, Hideyuki\| Takimiya, Kazuo\| Sekine, Hikaru\| Teranishi, Toshiharu\|
発行日	2012-09
出版物タイトル	Bulletin of the Chemical Society of Japan
巻	85巻
号	9号
資料タイプ	学術雑誌論文

Humidification of Base Flow Gas during Adult High-Frequency Oscillatory Ventilation:An Experimental Study Using a Lung Model

JaLCDOI	10.18926/AMO/48688
フルテキストURL	66_4_335.pdf
著者	Shiba, Naoki\| Nagano, Osamu\| Hirayama, Takahiro\| Ichiba, Shingo\| Ujike, Yoshihito\|
抄録	In adult high-frequency oscillatory ventilation (HFOV) with an R100 artificial ventilator, exhaled gas from patientʼs lung may warm the temperature probe and thereby disturb the humidification of base flow (BF) gas. We measured the humidity of BF gas during HFOV with frequencies of 6, 8 and 10Hz, maximum stroke volumes (SV) of 285, 205, and 160ml at the respective frequencies, and, BFs of 20, 30, 40l/min using an original lung model. The R100 device was equipped with a heated humidifier, HummaxⅡ, consisting of a porous hollow fiber in circuit. A 50-cm length of circuit was added between temperature probe (located at 50cm proximal from Y-piece) and the hollow fiber. The lung model was made of a plastic container and a circuit equipped with another HummaxⅡ. The lung model temperature was controlled at 37℃. The HummaxⅡ of the R100 was inactivated in study-1 and was set at 35℃ or 37℃ in study-2. The humidity was measured at the distal end of the added circuit in study-1 and at the proximal end in study-2. In study-1, humidity was detected at 6Hz (SV 285ml) and BF 20l/min, indicating the direct reach of the exhaled gas from the lung model to the temperature probe. In study-2 the absolute humidity of the BF gas decreased by increasing SV and by increasing BF and it was low with setting of 35℃. In this study setting, increasing the SV induced significant reduction of humidification of the BF gas during HFOV with R100.
キーワード	HFOV humidification
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2012-08
巻	66巻
号	4号
出版者	Okayama University Medical School
開始ページ	335
終了ページ	341
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2012 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	22918206
Web of Science KeyUT	000307918900006

Experimental Verification of Common-Mode Excitation Model for PCB Having Partially Narrow Return Path

JaLCDOI	10.18926/47029
フルテキストURL	mfe_36_2_083_089.pdf
著者	Watanabe, Tetsushi\| Wada, Osami\| Koga, Ryuji\| Toyota, Yoshitaka\| Miyashita, Takuya\|
抄録	Suppression of common-mode current is important to achieve electromagnetic compatibility of high-speed and high-density electronic circuits. The authors have focused on the common mode current flowing on a printed circuit board (PCB) to explain the excitation mechanism. A narrow ground pattern in microstrip structure excites common-mode current. In the previous paper, the authors explained the mechanism of common mode generation by means of "current division factor" for simple PCBs. The estimated radiation from a simple PCB agreed well with measured one. In this paper, the authors extend the theory to be applied to generalize ground structure. The validity of the theory is confirmed by comparing the measured radiation and the estimated value using the common-mode model for a test PCB. The estimated radiation agrees well with the measured one within 3 dB up to 900 MHz.
出版物タイトル	Memoirs of the Faculty of Engineering, Okayama University
発行日	2002-03
巻	36巻
号	2号
開始ページ	83
終了ページ	89
ISSN	0475-0071
言語	英語
論文のバージョン	publisher
NAID	120003497051

肺臓原基ノ形態學的發生ニ就テ（鳥類殊ニ十姉妹ニ於ケル檢索）

著者	金岡英雄\|
発行日	1934-10-31
出版物タイトル	岡山医学会雑誌
巻	46巻
号	10号
資料タイプ	学術雑誌論文

Highly Efficient RF-DC Conversion Circuits for Wireless Power Transmission

著者	山本綱之\|
発行日	2010-09-30
出版物タイトル
資料タイプ	学位論文

革新の経済学序説－製造業における考察－

JaLCDOI	10.18926/OER/40534
タイトル（別表記）	An Introductory Economic Study on Innovation －The Case of Manufacturing Industry－
フルテキストURL	oer_036_4_001_013.pdf
著者	武村昌介\|
抄録	The most important word is ‘innovator’ in the theory of Shumpetarian Hypothesis. That gives rise to the specific rivalry and competitive power in some vital facets of business fluctuation. This rivalry has both the innovative and strategic characteristics inside the firm. The notorious industrial policies used to depend on the good functions of production-investment circuit and cost-price one. None the less market fails. A series of the recent open market operations implemented by Japanese Central Bank, are related to a certain misunderstanding about our popular macroeconomic analysis. Let there be no mistake about it. In this article I will research the sustainable factors of R&D and the revised chain model inside the a few manufacturing firms and / or industries including semi-conductor industry. Besides we are going to make use of Japanese statistical materials about TFP comparing to those of U.S. and others as occasion demands. We can take notice that this work has some important fact findings in the article. Finally there will be explanation and emphasis about the distinguishing method between the firms of three types and the ‘inside’ problem.
出版物タイトル	岡山大学経済学会雑誌
発行日	2005-03-10
巻	36巻
号	4号
開始ページ	1
終了ページ	13
ISSN	0386-3069
関連URL	http://www.e.okayama-u.ac.jp/gakkai/
言語	日本語
論文のバージョン	publisher
NAID	120002576155

鳥取県三朝温泉に於ける二，三の放射性元素の存在について

JaLCDOI	10.18926/40342
タイトル（別表記）	ON THE EXISTENCE OF RADIUM B, RADIUM C AND THORIUM B IN MISASA HOT SPRINGS
フルテキストURL	pitsr_013_005_008.pdf
著者	佐藤三雄\|
抄録	The author tried to measure RaB, RaC and ThB in the hot spring waters using G-M counter and proved the existence of RaB and ThB in Misasa Hot Springs. To 100 liters of spring water ahout 20 gms of ferric chloride and then sodium hydroxide were added. Precipitate was dissolved in hydrochloric acid and after adding bismuth and lead, the solution was saturated with hydrogen sulfide. The precipitate of sulfides was filtered and ignited to ashes after drying. The β-activity of the ashes was measured by a mica-window type G-M counter with the recording circuits of scale of 16. Natural background was 50±5 connts per minutes. Six spring waters of Misasa, namely "Spring of Branch Laboratory", "Nakayu", "Gunze" "O-T-R", "Jwayu", and "Tsukiminoyu" were investigated. RaB was detected in all samples. ThB was found only in "Gunze" and "O-T-R". ThB content of "Gunze" was estimated, to be roughly 1×10(-12) Curie units per liter.
出版物タイトル	岡山大学温泉研究所報告
発行日	1953-12
巻	13巻
開始ページ	5
終了ページ	8
ISSN	0369-7142
言語	英語
論文のバージョン	publisher
NAID	120002484878

Design and performance of the ABCD3TA ASIC for readout of silicon strip detectors in the ATLAS semiconductor tracke

著者	Campabadal, F\| Fleta, C\| Key, M\| Lozano, M\| Martinez, C\| Pellegrini, G\| Rafi, J M\| Ullan, M\| Johansen, L G\| Mohn, B\| Oye, O\| Solberg, A O\| Stugu, B\| Ciocio, A\| Ely, R\| Fadeyev, V\| Gilchriese, M\| Haber, C\| Siegrist, J\| Spieler, H\| Vu, C\| Bell, P J\| Charlton, D G\| Dowell, J D\| Gallop, B J\| Homer, R J\| Jovanovic, P\| Mahout, G\| McMahon, T J\| Wilson, J A\| Barr, A J\| Carter, J R\| Goodrick, M J\| Hill, J C\| Lester, C G\| Parker, M A\| Robinson, D\| Anghinolfi, F\| Chesi, E\| Jarron, P\| Kaplon, J\| Macpherson, A\| Pernegger, H\| Pritchard, T\| Roe, S\| Rudge, A\| Weilhammer, P\| Bialas, W\| Dabrowski, W\| Dwuznik, M\| Toczek, B\| Koperny, S\| Bruckman, P\| Gadomski, S\| Gornicki, E\| Malecki, P\| Moszczynski, A\| Stanecka, E\| Szczygiel, R\| Turala, M\| Wolter, W\| Andricek, L\| Bethke, S\| Hauff, D\| Kudlaty, J\| Lutz, G\| Moser, H -G\| Nisius, R\| Richter, R\| Schieck, J\| Colijn, A-P\| Cornelissen, T\| Gorfine, G W\| Hartjes, F G\| Hessey, N P\| Jong, P de\| Kluit, R\| Koffeman, E\| Muijs, A J. M\| Peeters, S J. M\| Eijk, B van\| Nakano, I\| Tanaka, R\| Dorholt, O\| Danielsen, K M\| Huse, T\| Sandaker, H\| Stapnes, S\| Kundu, N\| Nickerson, R B\| Weidberg, A\| Bohm, J\| Mikestikova, M\| Stastny, J\| Broklova, Z\| Broz, J\| Dolezal, Z\| Kodys, P\| Kubik, P\| Reznicek, P\| Vorobel, V\| Wilhelm, I\| Cermak, P\| Chren, D\| Horazdovsky, T\| Linhart, V\| Pospisil, S\| Sinor, M\| Solar, M\| Sopko, B\| Stekl, I\| Apsimon, R J\| Batchelor, L E\| Bizzell, J P\| Falconer, N G\| French, M J\| Gibson, M D\| Haywood, S J\| Matson, R M\| McMahon, S J\| Morrissey, M\| Murray, W J\| Phillips, P W\| Morrissey, M\| Murray, W J\| Phillips, P W\| Tyndel, M\| Villani, E G\| Cosgrove, D P\| Dorfan, D E\| Grillo, A A\| Kachiguine, S\| Rosenbaum, F\| Sadrozinski, H F. -W\| Seiden, A\| Spencer, E\| Wilder, M\| Akimoto, T\| Hara, K\| Tanizaki, K\| Bingefors, N\| Brenner, R\| Ekelof, T\| Eklund, L\| Bernabeu, J\| Civera, J V\| Costa, M J\| Fuster, J\| Garcia, C\| Garcia-Navarro, J E\| Gonzalez-Sevilla, S\| Lacasta, C\| Llosa, G\| Marti-Garcia, S\| Modesto, P\| Sanchez, F J\| Sospedra, L\| Vos, M\|
発行日	2005-11
出版物タイトル	Nuclear Instruments and Methods in Physics Research Section A: Accelerators
巻	552巻
号	3号
資料タイプ	学術雑誌論文

Fabrication of a logic gate circuit based on ambipolar field-effect transistors with thin films of C<sub>60</sub> and pentacene

著者	Kuwahara, Eiji\| Kusai, Haruka\| Nagano, Takayuki\| Takayanagi, Toshio\| Kubozono, Yoshihiro\|
発行日	2005-09-26
出版物タイトル	Chemical Physics Letters
巻	413巻
号	4-6号
資料タイプ	学術雑誌論文