検索結果 - 岡山大学学術成果リポジトリ

Overcoming epithelial-mesenchymal transition-mediated drug resistance with monensin-based combined therapy in non-small cell lung cancer

フルテキストURL	fulltext.pdf figure1.tif figure2.tif figure3.tif spfigure1.tif spfigure2.tif SupTable1.xlsx
著者	Ochi, Kosuke\| Suzawa, Ken\| Tomida, Shuta\| Shien, Kazuhiko\| Takano, Jui\| Miyauchi, Shunsaku\| Takeda, Tatsuaki\| Miura, Akihiro\| Araki, Kota\| Nakata, Kentaro\| Yamamoto, Hiromasa\| Okazaki, Mikio\| Sugimoto, Seiichiro\| Shien, Tadahiko\| Yamane, Masaomi\| Azuma, Kazuo\| Okamoto, Yoshiharu\| Toyooka, Shinichi\|
キーワード	Monensin Epithelial-mesenchymal transition Non-small cell lung cancer Drug repositioning Drug resistance
備考	This fulltext is available in Jul. 2021.\|
発行日	2020-08-27
出版物タイトル	Biochemical and Biophysical Research Communications
巻	529巻
号	3号
出版者	Academic Press
開始ページ	760
終了ページ	765
ISSN	0006-291X
NCID	AA00564395
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	32736704
DOI	10.1016/j.bbrc.2020.06.077
Web of Science KeyUT	000555780500037
関連URL	iaVersionOf https://doi.org/10.1016/j.bbrc.2020.06.077

Prognostic value of OCT4A and SPP1C transcript variant co-expression in early-stage lung adenocarcinoma

フルテキストURL	fulltext.pdf
著者	Koshimune, Seijiro\| Kosaka, Mitsuko\| Mizuno, Nobuhiko\| Yamamoto, Hiromasa\| Miyamoto, Tomoyuki\| Ebisui, Kohta\| Toyooka, Shinichi\| Ohtsuka, Aiji\|
キーワード	OCT4 SPP1 lung adenocarcinoma tumour-initiating cell cancer stem cell cell migration
発行日	2020-06-05
出版物タイトル	BMC Cancer
巻	20巻
号	1号
出版者	BMC
開始ページ	521
ISSN	1471-2407
NCID	AA12034763
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s). 2020
論文のバージョン	publisher
PubMed ID	32503462
DOI	10.1186/s12885-020-06969-0
Web of Science KeyUT	000540257600003
関連URL	isVersionOf https://doi.org/10.1186/s12885-020-06969-0

Influences of preoperative metformin on immunological factors in early breast cancer

フルテキストURL	CCP_fulltext.pdf
著者	Tsukioki, Takahiro\| Shien, Tadahiko\| Tanaka, Takehiro\| Suzuki, Yoko\| Kajihara, Yukiko\| Hatono, Minami\| Kawada, Kengo\| Kochi, Mariko\| Iwamoto, Takayuki\| Ikeda, Hirokuni\| Taira, Naruto\| Doihara, Hiroyoshi\| Toyooka, Shinichi\|
キーワード	Breast cancer Metformin Preoperative Tils CD8 PD-L1
発行日	2020-06-12
出版物タイトル	Cancer Chemotherapy and Pharmacology
巻	86巻 86巻
号	1号 1号
出版者	Springer
開始ページ	55 55
終了ページ	63 63
ISSN	0344-5704
NCID	AA00598397
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	©Author(s)
論文のバージョン	publisher
PubMed ID	32533334
DOI	10.1007/s00280-020-04092-2
Web of Science KeyUT	000539841500002
関連URL	isVersionOf https://doi.org/10.1007/s00280-020-04092-2

NSAS-BC02 substudy of chemotherapy-induced amenorrhea (CIA) in premenopausal patients who received either taxane alone or doxorubicin(A) cyclophosphamide(C) followed by taxane as postoperative chemotherapy

著者	Iwamoto, Takayuki\| Hara, Fumikata\| Uemura, Yukari\| Mukai, Hirofumi\| Watanabe, Toru\| Ohashi, Yasuo\|
キーワード	Chemotherapy-induced amenorrhea Taxane Taxane Breast cancer Guarantee-time bias Premenopause
発行日	2020-05-28
出版物タイトル	Breast Cancer Research and Treatment
巻	182巻
号	2号
出版者	Springer
開始ページ	325
終了ページ	332
ISSN	0167-6806
NCID	AA10623184
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	32462261
DOI	10.1007/s10549-020-05692-5
Web of Science KeyUT	000539434600002
関連URL	isVersionOf https://doi.org/10.1007/s10549-020-05692-5

Impact of breast surgery in de novo stage IV breast cancer

フルテキストURL	fulltext.pdf
著者	Shien, Tadahiko\|
発行日	2019-03
出版物タイトル	Translational Cancer Research
巻	8巻
号	Suppl. 2号
出版者	AME Publishing
開始ページ	S118
終了ページ	S119
ISSN	2218-676X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	publisher
DOI	10.21037/tcr.2018.11.19
関連URL	isVersionOf https://doi.org/10.21037/tcr.2018.11.19

Adjuvant and neoadjuvant therapy for breast cancer

フルテキストURL	fulltext.pdf
著者	Shien, Tadahiko\| Iwata, Hiroji\|
キーワード	breast cancer adjuvant neoadjuvant
備考	This is a pre-copyedited, author-produced version of an article accepted for publication in Japanese Journal of Clinical Oncology following peer review. The version of record TTadahiko Shien, Hiroji Iwata, Adjuvant and neoadjuvant therapy for breast cancer, Japanese Journal of Clinical Oncology, Volume 50, Issue 3, March 2020, Pages 225–229 is available online at: https://doi.org/10.1093/jjco/hyz213.\|
発行日	2020-01-28
出版物タイトル	Japanese Journal of Clinical Oncology
巻	50巻
号	3号
出版者	Oxford University Press
開始ページ	225
終了ページ	229
ISSN	0368-2811
NCID	AA00690866
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	Copyright © 2020 Oxford University Press
論文のバージョン	author
PubMed ID	32147701
DOI	10.1093/jjco/hyz213
Web of Science KeyUT	000536439500001
関連URL	isVersionOf https://doi.org/10.1093/jjco/hyz213

Risk of Gynecologic Cancer as Second versus First Primary Cancer in Japan

JaLCDOI	10.18926/AMO/58268
フルテキストURL	74_2_109.pdf
著者	Ogawa, Chikako\| Nakamura, Keiichiro\| Matsuoka, Hirofumi\| Matsubara, Yuko\| Haraga, Junko\| Masuyama, Hisashi\|
抄録	This study aimed to determine whether the risk conferred by gynecologic cancer (GC) as second primary cancer (SPC) differs from that associated with GC as first primary cancer (FPC). We investigated the correlations between FPC/SPC and the characteristics and prognoses of 1,645 GC patients (701 with cervical cancer [CC], 641 with endometrial cancer [EM], and 303 with ovarian cancer [OV]). The χ2 test and the Kaplan–Meier method were used to determine whether FPC/SPC and the characteristics and prognoses of GC patients. Of the SPC patients, 26 (3.7%) had CC, 53 (8.3%) had EM, and 31 (10.2%) had OV. The most common previous cancer type in SPC of GC patients was breast cancer, which was observed in 13 patients (50.0%) with CC, 23 (43.4%) with EM, and 16 (51.6%) with OV. In all patients with CC, EM, and OV as SPC, the stage was significantly associated with recurrence. There were no significant differences in the morbidity or mortality of CC, EM, or OV patients between those with FPC and those with SPC. The risk of SPC development in GC patients varied, ranging from 3.5% (CC) to 10.3% (OV) of patients.
キーワード	second primary cancer gynecologic cancer prognosis
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-04
巻	74巻
号	2号
出版者	Okayama University Medical School
開始ページ	109
終了ページ	114
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32341584
Web of Science KeyUT	000528278500003
NAID	120006839447

The Efficacy of Software to Help Patients Understand Drug for Adjuvant Treatment for Breast Cancer: A Pilot Randomized Controlled Trial

JaLCDOI	10.18926/AMO/58266
フルテキストURL	74_2_95.pdf
著者	Kuba, Sayaka\| Yamanouchi, Kosho\| Morita, Michi\| Sakimura, Chika\| Inamasu, Eiko\| Hatachi, Toshiko\| Otsubo, Ryota\| Matsumoto, Megumi\| Yano, Hiroshi\| Miyamoto, Junya\| Sato, Shuntaro\| Nakagawa, Hiroo\| Kanetaka, Kengo\| Takatsuki, Mitsuhisa\| Nagayasu, Takeshi\| Eguchi, Susumu\|
抄録	We assessed the usefulness of ChemoCalc, a software package for calculating drug costs, in helping patients understand these costs. We randomly assigned, in a 1 : 1 ratio, 20 women who had undergone surgery for early breast cancer to a group that discussed adjuvant treatment with their physicians using the ChemoCalc software (ChemoCalc group) or a group that discussed adjuvant treatment without ChemoCalc (Usual Explanation group). The participants completed a five-grade evaluation questionnaire after these discussions. The primary endpoint was the intergroup comparison of the questionnaire scores regarding participants’ understanding of their treatment-associated drug costs. Median age was not significantly different between the ChemoCalc group and Usual Explanation group (57 vs. 50, respectively; p=0.27). Patients in the ChemoCalc group had a significantly higher perceived level of understanding of the drug cost than those in the Usual Explanation group (5 [4-5] vs. 2.5 [1-5], respectively; p=0.002). Scores related to the patients’ perception that understanding drug costs is an important part of breast cancer treatment were also higher in the ChemoCalc group than the Usual Explanation group (5 [2-5] vs. 3 [1-5], respectively; p=0.049). ChemoCalc was found to be useful for understanding drug costs.
キーワード	breast cancer drug costs ChemoCalc
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2020-04
巻	74巻
号	2号
出版者	Okayama University Medical School
開始ページ	95
終了ページ	101
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32341582
Web of Science KeyUT	000528278500001
NAID	120006839445

Alpinia zerumbet (Pers.): Food and Medicinal Plant with Potential In Vitro and In Vivo Anti-Cancer Activities

フルテキストURL	fulltext.pdf
著者	Zahra, Maram Hussein\| Salem, Tarek A. R.\| El-Aarag, Bishoy\| Yosri, Nermeen\| EL-Ghlban, Samah\| Zaki, Kholoud\| Marei, Amel H.\| Abd El-Wahed, Aida\| Saeed, Aamer\| Khatib, Alfi\| AlAjmi, Mohamed F.\| Shathili, Abdulrahman M.\| Xiao, Jianbo\| Khalifa, Shaden A. M.\| El-Seedi, Hesham R.\|
キーワード	Alpinia zerumbet 5,6-dehydrokawain Ehrlich ascites carcinoma anti-tumor anti-oxidant
発行日	2019-07-08
出版物タイトル	Molecules
巻	24巻
号	13号
出版者	MDPI
開始ページ	2495
ISSN	1420-3049
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 by the authors.
論文のバージョン	publisher
PubMed ID	31288458
DOI	10.3390/molecules24132495
Web of Science KeyUT	000476700300149
関連URL	isVersionOf https://doi.org/10.3390/molecules24132495

Cancer Cell-Derived Granulocyte-Macrophage Colony-Stimulating Factor Is Dispensable for the Progression of 4T1 Murine Breast Cancer

フルテキストURL	fulltext.pdf
著者	Yoshimura, Teizo\| Nakamura, Kaoru\| Li, Chunning\| Fujisawa, Masayoshi\| Shiina, Tsuyoshi\| Imamura, Mayu\| Li, Tiantian\| Mukaida, Naofumi\| Matsukawa, Akihiro\|
キーワード	macrophages chemokines cytokines inflammation tumor microenvironment breast cancer
発行日	2019-12-16
出版物タイトル	International Journal of Molecular Sciences
巻	20巻
号	24号
出版者	MDPI
ISSN	1422-0067
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 by the authors.
論文のバージョン	publisher
PubMed ID	31888216
DOI	10.3390/ijms20246342
Web of Science KeyUT	000506840100235
関連URL	isVersionOf https://doi.org/10.3390/ijms20246342

A Multicenter, Open-label, Clinical Trial to Assess the Effectiveness and Safety of Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced-intensity Conditioning in Relapsed/refractory Anaplastic Large-cell Lymphoma in Children

JaLCDOI	10.18926/AMO/57959
フルテキストURL	74_1_89.pdf
著者	Kada, Akiko\| Fukano, Reiji\| Mori, Tetsuya\| Kamei, Michi\| Tanaka, Fumiko\| Ueyama, Junichi\| Sekimizu, Masahiro\| Osumi, Tomoo\| Mori, Takeshi\| Koga, Yuhki\| Ohki, Kentaro\| Fujita, Naoto\| Mitsui, Tetsuo\| Saito, Akiko M.\| Hashimoto, Hiroya\| Kobayashi, Ryoji\|
抄録	No standard treatment for relapsed or refractory anaplastic large-cell lymphoma (ALCL) has been established. This study is a multicenter, open-label trial to examine the effectiveness and safety of transplantation with reduced-intensity conditioning (RIC) for patients under 20 years old with relapsed or refractory ALCL. We defined RIC as the administration of fludarabine (30 mg/m2/day) for five days plus melphalan (70 mg/m2/day) for two days and total body irradiation at 4 Gy, followed by allogeneic hematopoietic stem cell transplantation.
キーワード	anaplastic large-cell lymphoma relapsed/refractory fludarabine melphalan total body irradiation
Amo Type	Clinical Study Protocol
出版物タイトル	Acta Medica Okayama
発行日	2020-02
巻	74巻
号	1号
出版者	Okayama University Medical School
開始ページ	89
終了ページ	94
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32099255
Web of Science KeyUT	000516606200014
NAID	120006795626

A Promising New Anti-Cancer Strategy: Iron Chelators Targeting CSCs

JaLCDOI	10.18926/AMO/57946
フルテキストURL	74_1_1.pdf
著者	Chen, Yuehua\| Ohara, Toshiaki\| Xing, Boyi\| Qi, Jiping\| Noma, Kazuhiro\| Matsukawa, Akihiro\|
抄録	Iron is a trace but vital element in the human body and is necessary for a multitude of crucial processes in life. However, iron overload is known to induce carcinogenesis via oxidative stress. Cancer cells require large amounts of iron for their rapid division and cell growth. Iron was recently found to play a role in cancer stem cells (CSCs); it maintains stemness during development. Iron also plays an important role in stemness by moderating reactive oxygen species. Thus, iron metabolism in CSCs is a promising therapeutic target. In this review, we summarize the roles of iron in cancer cells and CSCs. We also summarize anti-cancer therapeutic studies with iron chelators and describe our expectation of a new therapeutic strategy for CSCs on the basis of our findings.
キーワード	cancer stem cell stemness iron chelation chemotherapy
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2020-02
巻	74巻
号	1号
出版者	Okayama University Medical School
開始ページ	1
終了ページ	6
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32099242
Web of Science KeyUT	000516606200001
NAID	120006795613

Associations in tumor infiltrating lymphocytes between clinicopathological factors and clinical outcomes in estrogen receptor-positive/human epidermal growth factor receptor type 2 negative breast cancer

フルテキストURL	OL17_2_2177.pdf
著者	Miyoshi, Yuichiro\| Shien, Tadahiko\| Ogiya, Akiko\| Ishida, Naoko\| Yamazaki, Kieko\| Horii, Rie\| Horimoto, Yoshiya\| Masuda, Norikazu\| Yasojima, Hiroyuki\| Inao, Touko\| Osako, Tomofumi\| Takahashi, Masato\| Tomioka, Nobumoto\| Wanifuchi‑Endo, Yumi\| Hosoda, Mitsuchika\| Doihara, Hiroyoshi\| Yamashita, Hiroko\|
キーワード	breast cancer estrogen receptor positive human epidermal growth factor receptor type 2 negative prognosis tumor infiltrating lymphocytes
発行日	2018-12-19
出版物タイトル	Oncology Letters
巻	17巻
号	2号
出版者	Spandidos Publications
開始ページ	2177
終了ページ	2186
ISSN	1792-1074
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	publisher
PubMed ID	30675282
DOI	10.3892/ol.2018.9853
Web of Science KeyUT	000459551800096
関連URL	isVersionOf https://doi.org/10.3892/ol.2018.9853

Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness

フルテキストURL	fulltext.pdf
著者	Chen, Youyi\| Sumardika, I Wayan\| Tomonobu, Nahoko\| Kinoshita, Rie\| Inoue, Yusuke\| Iioka, Hidekazu\| Mitsui, Yosuke\| Saito, Ken\| Ruma, I Made Winarsa\| Sato, Hiroki\| Yamauchi, Akira\| Murata, Hitoshi\| Yamamoto, Ken-ichi\| Tomida, Shuta\| Shien, Kazuhiko\| Yamamoto, Hiromasa\| Soh, Junichi\| Futami, Junichiro\| Kubo, Miyoko\| Putranto, Endy Widya\| Murakami, Takashi\| Liu, Ming\| Hibino, Toshihiko\| Nishibori, Masahiro\| Kondo, Eisaku\| Toyooka, Shinichi\| Sakaguchi, Masakiyo\|
発行日	2019-07
出版物タイトル	Neoplasia
巻	21巻
号	7号
開始ページ	627
終了ページ	640
ISSN	1522-8002
NCID	AA11470191
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 The Authors.
論文のバージョン	publisher
PubMed ID	31100639
DOI	10.1016/j.neo.2019.04.006
Web of Science KeyUT	000472189700001
関連URL	isVersionOf https://doi.org/10.1016/j.neo.2019.04.006

Impact of Body Mass Index of Japanese Gallbladder Cancer Patients on their Postoperative Outcomes

JaLCDOI	10.18926/AMO/56458
フルテキストURL	73_1_51.pdf
著者	Fujii, Masakuni\| Fujimoto, Kenji\| Yabe, Syuntaro\| Nasu, Junichiro\| Miyaike, Jiro\| Yoshioka, Masao\| Shiode, Junji\| Yamamoto, Kazuhide\| Matsuda, Shinya\|
抄録	We investigated the relationship between body mass index (BMI) and postoperative outcomes in 450 gallbladder cancer patients in Japan. We collected patient information, including sex, age, underlying disease, BMI, stage, surgery method, postoperative time to discharge, and postoperative Medicare fees, from the Japanese administrative database associated with the Diagnosis Procedure Combination system. We classified patient BMIs as underweight (BMI<18.5 kg/m2), normal (BMI≥18.5 kg/m2 and <25 kg/m2) or overweight/obese (BMI≥25 kg/m2), then investigated the relationship between these categories and two postoperative outcomes: time to discharge and postoperative Medicare fees. The median postoperative time to discharge was 12 days in all patients, and 12 days in each of the three weight groups (p=0.62, n.s.). The median postoperative Medicare fees from surgery until discharge were (USD): all patients, $5,002; underweight, $5,875; normal weight, $4,797; and overweight/obese, $5,179 (p=0.146, n.s.). A multivariate analysis with adjustment for competing risk factors revealed that BMI was not associated with increased risk of longer postoperative time to discharge (normal weight: HR 1.17, p=0.29; overweight/obese: HR 1.17, p=0.37) or higher postoperative Medicare fees (OR 0.99, p=0.86, n.s.). Thus, high BMI was not found to be a factor for poor postoperative outcomes in Japanese patients with gallbladder cancer.
キーワード	body mass index gallbladder cancer surgery obesity
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-02
巻	73巻
号	1号
出版者	Okayama University Medical School
開始ページ	51
終了ページ	59
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	30820054

Hormonal Therapy Resistant Estrogen-receptor Positive Metastatic Breast Cancer Cohort (HORSE-BC) Study : Current Status of Treatment Selection in Japan

JaLCDOI	10.18926/AMO/56172
フルテキストURL	72_4_369.pdf
著者	Iwamoto, Takayuki\| Taira, Naruto\| Fujisawa, Tomomi\| Araki, Kazuhiro\| Sakamaki, Kentaro\| Sangai, Takafumi\| Kikawa, Yuichiro\| Shien, Tadahiko\| Takao, Shintaro\| Sato, Masako\| Goto, Yoshinari\| Yoshida, Takashi\| Takahashi, Masato\| Aihara, Tomohiko\| Mukai, Hirofumi\|
抄録	The Hormonal therapy resistant estrogen-receptor positive metastatic breast cancer cohort (HORSE-BC) study is a multicenter observational study evaluating the efficacy and safety of secondary endocrine therapy (ET) for postmenopausal cases of metastatic breast cancer (MBC) with poor response to primary ET. In this initial report we analyze the HORSE-BC baseline data to clarify the current status of treatment selection for MBC in Japan. Baseline data for the 50 patients enrolled in HORSE-BC were analyzed, including patient characteristics, types of secondary ET, and reasons for selecting secondary ET. Postoperative recurrence was detected in 84% of patients (42/50) and de novo stage IV breast cancer in 16% (8/50). Forty-one patients (41/50; 82%) received fulvestrant, 5 patients (10%) received selective estrogen receptor modulators (SERMs), 3 patients (6%) received ET plus a mammalian target of rapamycin (mTOR) inhibitor, and 1 patient received an aromatase inhibitor (AI) as the secondary ET. Forty-five patients selected their secondary ET based on its therapeutic effect, while 14 patients selected it based on side effects. Most patients with progression after primary ET selected fulvestrant as the secondary ET based on its therapeutic and side effects. We await the final results from the HORSE-BC study.
キーワード	breast cancer secondary endocrine therapy low sensitivity primary endocrine therapy fulvestrant
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2018-08
巻	72巻
号	4号
出版者	Okayama University Medical School
開始ページ	369
終了ページ	374
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	30140084

Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer

フルテキストURL	J_Cell_Biochem_116_10_2146.pdf
著者	Eguchi , Taka\| Prince, Thomas\| Wegiel, Barbara\| Calderwood, Stuart K.\|
キーワード	CANCER FINGER-1 INVASION MYELOID NUCLEAR BODY SUMO ZINC
発行日	2015-04-21
出版物タイトル	Journal of cellular biochemistry
巻	116巻
号	10号
出版者	Wiley
開始ページ	2146
終了ページ	2154
ISSN	0730-2312
NCID	AA1052210X
資料タイプ	学術雑誌論文
言語	日本語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	25903835
DOI	10.1002/jcb.25203
Web of Science KeyUT	000359809400004
関連URL	isVersionOf https://doi.org/10.1002/jcb.25203

Tumour-infiltrating lymphocytes (TILs)-related genomic signature predicts chemotherapy response in breast cancer

フルテキストURL	K0005687_abstract_review.pdf K0005687_summary.pdf K0005687_fulltext.pdf K0005687_figs.pdf
著者	河内麻里子\|
発行日	2018-03-23
資料タイプ	学位論文
学位授与番号	甲第5687号
学位授与年月日	2018-03-23
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語

平成28年度岡山医学会賞がん研究奨励賞（林原賞・山田賞）

タイトル（別表記）	The 2016 Incentive Award of the Okayama Medical Association in Cancer Research (2016 Hayashibara Prize and Yamada Prize)
フルテキストURL	129_89.pdf
著者	藤田洋史\|
出版物タイトル	岡山医学会雑誌
発行日	2017-08-01
巻	129巻
号	2号
開始ページ	89
終了ページ	91
ISSN	0030-1558
関連URL	https://doi.org/10.4044/joma.129.89
言語	日本語
著作権者	Copyright (c) 2017 岡山医学会
論文のバージョン	publisher
DOI	10.4044/joma.129.89
NAID	130006039368

Lesion Size on Ultrasonography Predicts Potential Invasion in Ductal Carcinoma in situ Preoperatively Diagnosed by Breast Needle Biopsy

JaLCDOI	10.18926/AMO/55206
フルテキストURL	71_3_233.pdf
著者	Shimoyama, Kyoko\| Osako, Tomo\| Mitsuhashi, Toshiharu\| Akiyama, Futoshi\| Iwase, Takuji\|
抄録	Ductal carcinoma in situ (DCIS) of the breast has no potential to metastasize, but over 20% of cases preoperatively diagnosed as DCIS are upstaged on final pathology. The rates of upstaging and the predictors for invasion on final pathology were evaluated. For 240 primary breast cancers, radiological findings on mammography, ultrasonography, and magnetic resonance imaging were investigated along with pathological and clinical information. Univariate and multivariate analyses were performed to identify predictors of potential invasion. Of the 240 breast cancers, 68 (28.3%) showed invasion on final pathology, and 5 (2.5%) had sentinel node metastasis. The multivariate analysis identified five independent predictors: non-mass lesions >2.4 cm on ultrasonography (odds ratio [OR] 2.84, 95% confidence interval [CI] 1.02-7.95, p=0.047), comedo-type histology (OR 6.89, 95% CI 1.89-25.08, p<0.01), solid-type histology (OR 7.97, 95% CI 2.08-30.49, p<0.01), palpable mass (OR 2.63, 95% CI 1.05-6.64, p=0.04), and bloody nipple discharge (OR 4.61, 95% CI 1.20-17.66, p=0.02). These five predictors were associated with invasion on final pathology and may help select candidates for sentinel node biopsy.
キーワード	breast cancer DCIS breast needle biopsy imaging examination sentinel node biopsy
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2017-06
巻	71巻
号	3号
出版者	Okayama University Medical School
開始ページ	233
終了ページ	240
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	28655943