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フルテキストURL fulltext20231223-01.pdf
著者 Matsuo, Toshihiko| Tanaka, Takehiro| Yamada, Kiyoshi| Nose, Motoko| Tanimoto, Yasushi|
キーワード debridement eyelid lacrimal sac Mycobacterium abscessus nontuberculous mycobacteria
発行日 2023-12-21
出版物タイトル Clinical Case Reports
巻 11巻
号 12号
出版者 Wiley
開始ページ e8364
ISSN 2050-0904
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 The Authors.
論文のバージョン publisher
PubMed ID 38130855
DOI 10.1002/ccr3.8364
Web of Science KeyUT 001128230600001
関連URL isVersionOf https://doi.org/10.1002/ccr3.8364
JaLCDOI 10.18926/AMO/66156
フルテキストURL 77_6_635.pdf
著者 Ikeda, Tomohiro| Okamura, Kazunori| Hasegawa, Masaki| Tanaka, Satoshi| Kanai, Shusaku|
抄録 In the management of post-injury patients with activity limitations, methods to prevent musculoskeletal disorders and hasten recovery are important. This randomized controlled, single-blinded study was a preliminary investigation of the combined effect of nutritional support with neuromuscular electrical stimulation (NMES) on muscle strength and thickness. Healthy young adult males (median age, 21 years) were enrolled; each of their hands was randomly assigned to one of the following four groups: Placebo, Nutrition, NMES, and Nutrition + NMES. All participants received whey protein or placebo (3x/week for 6 weeks) and NMES training (3x/week for 6 weeks) on the abductor digiti minimi (ADM) muscle of either the left or right hand. ADM muscle strength and thickness were analyzed at baseline and at week 7. We analyzed 38 hands (9 Placebo, 10 Nutrition, 9 NMES, 10 Nutrition + NMES). There was significantly greater muscle strengthening in the Nutrition + NMES group compared to the Placebo group or the NMES group, but no significant difference in gain of muscle thickness. The combined intervention may be effective in improving muscle strength. Future clinical trials targeting various muscles after sports-related injuries are warranted.
キーワード whey protein electrical stimulation muscle strength healthy volunteers
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-12
巻 77巻
号 6号
出版者 Okayama University Medical School
開始ページ 635
終了ページ 645
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38145938
Web of Science KeyUT 001164631200009
JaLCDOI 10.18926/AMO/66155
フルテキストURL 77_6_627.pdf
著者 Hibino, Yumi| Okazawa-Sakai, Mika| Yokoyama, Takanori| Fujimoto, Etsuko| Okame, Shinichi| Teramoto, Norihiro| Takehara, Kazuhiro|
抄録 To explore the incidence of abnormal vaginal cytology after total laparoscopic hysterectomy for the treatment of cervical intraepithelial neoplasia 3, we retrospectively analyzed the medical records of patients treated at NHO Shikoku Cancer Center (Japan) in 2014-2019. The cases of 99 patients who underwent a laparoscopic (n=36) or open (n=63) hysterectomy and postoperative follow-up were examined. Abnormal vaginal cytology was detected in 13.9% (5/36) of the laparoscopic-surgery (LS) group and 14.3% (9/63) of the open-surgery (OS) group. A vaginal biopsy was performed at the physicians’ discretion; one LS patient and six OS patients were diagnosed with vaginal intraepithelial neoplasia. The cumulative incidence of abnormal vaginal cytology at 3 years post-hysterectomy was 21.4% (LS group) and 20.5% (OS group), a nonsignificant difference. A multivariate analysis showed that age > 50 years was the only independent risk factor for abnormal vaginal cytology among the covariates examined including age; body mass index; histories of vaginal delivery, abdominal surgery, and smoking; and surgical approach (hazard ratio 8.11; 95% confidence interval 1.73-37.98; p=0.01). These results suggest that the occurrence of abnormal vaginal cytology after a hysterectomy may not be influenced by the laparoscopic procedure but is associated with older age.
キーワード total laparoscopic hysterectomy vaginal intraepithelial neoplasia cervical intraepithelial neoplasia vaginal cytology risk factor
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-12
巻 77巻
号 6号
出版者 Okayama University Medical School
開始ページ 627
終了ページ 634
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38145937
Web of Science KeyUT 001164631200008
JaLCDOI 10.18926/AMO/66153
フルテキストURL 77_6_613.pdf
著者 Miyake, Yoshiaki| Namba, Yoshifumi| Mitani, Shigeru| Umehara, Norifumi| Kawamoto, Toyohiro| Furuichi, Shuro|
抄録 The relationship between osteoarthritis (OA) of the lower extremity and shoulder OA has not been established. This study evaluated the prevalence of shoulder OA in patients with knee OA. We collected contrast-enhanced computed tomography (CECT) images of the shoulder joints of 105 patients with knee OA that were taken 1 week after they underwent primary knee arthroplasty to check for venous thromboembolism (VTE). The images were compared with CECT images of 110 control-group patients that were taken for the purpose of differentiating VTE. Shoulder OA was present in a significantly higher percentage of patients with knee arthroplasty than controls (29% versus 15%), and the difference was particularly pronounced in patients in their 70s (33%) compared to age-matched controls (11%). Patients with knee OA often use arm support to stand up or walk due to knee joint pain and muscle weakness, which places the weight-bearing shoulder at risk of developing OA.
キーワード shoulder osteoarthritis knee osteoarthritis weight-bearing shoulder knee arthroplasty
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-12
巻 77巻
号 6号
出版者 Okayama University Medical School
開始ページ 613
終了ページ 618
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38145935
Web of Science KeyUT 001164631200006
JaLCDOI 10.18926/AMO/66151
フルテキストURL 77_6_595.pdf
著者 Bando, Takashi| Chuma, Masayuki| Hamano, Hirofumi| Niimura, Takahiro| Okada, Naoto| Kondo, Masateru| Izumi, Yuki| Ishida, Shunsuke| Yoshioka, Toshihiko| Asada, Mizuho| Zamami, Yoshito| Takechi, Kenshi| Goda, Mitsuhiro| Miyata, Koji| Yagi, Kenta| Izawa-Ishizawa, Yuki| Azuma, Momoyo| Yanagawa, Hiroaki| Tasaki, Yoshikazu| Ishizawa, Keisuke|
抄録 There is a growing concern about the relationship between vancomycin-associated nephrotoxicity (VAN) and concomitant use of nephrotoxins. We examined this relationship by combined retrospective analyses of two real-world databases. Initially, the FDA Adverse Event Reporting System (FAERS) was analyzed for the effects of concomitant use of one or more nephrotoxins on VAN and the types of combinations of nephrotoxins that exacerbate VAN. Next, electronic medical records (EMRs) of patients who received vancomycin (VCM) at Tokushima University Hospital between January 2006 and March 2019 were examined to confirm the FAERS analysis. An elevated reporting odds ratio (ROR) was observed with increases in the number of nephrotoxins administered (VCM + one nephrotoxin, adjusted ROR (95% confidence interval [CI]) 1.67 [1.51-1.85]; VCM + ≥2 nephrotoxins, adjusted ROR [95% CI] 1.54 [1.37-1.73]) in FAERS. EMRs analysis showed that the number of nephrotoxins was associated with higher incidences of VAN [odds ratio: 1.99; 95% CI: 1.42-2.78]. Overall, concomitant use of nephrotoxins was associated with an increased incidence of VAN, especially when at least one of those nephrotoxins was a renal hypoperfusion medication (furosemide, non-steroidal anti-inflammatory drugs, and vasopressors). The concomitant use of multiple nephrotoxins, especially including renal hypoperfusion medication, should be avoided to prevent VAN.
キーワード vancomycin-associated nephrotoxicity polypharmacy nephrotoxin spontaneous adverse event reporting database electronic medical records
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-12
巻 77巻
号 6号
出版者 Okayama University Medical School
開始ページ 595
終了ページ 605
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38145933
Web of Science KeyUT 001164631200004
JaLCDOI 10.18926/AMO/66148
フルテキストURL 77_6_567.pdf
著者 Matsumoto, Naomi| Higuchi, Chigusa| Miyaji, Chikara| Mitsuhashi, Toshiharu| Hagiya, Hideharu| Takao, Soshi| Yorifuji, Takashi|
抄録 This paper presents the results of a series of surveys conducted from July 2021 to March 2023 to investigate the post-vaccination adverse reactions to the mRNA-1273 (Moderna) vaccine among faculty, staff, and students at Okayama University. These studies complement the official surveys conducted by the Ministry of Health, Labour and Welfare (MHLW) and provide a more representative picture of adverse reactions in the general population including large numbers of healthy young people. Pain, swelling, redness at the injection site, fever, headache, and malaise were the main adverse reactions reported. The proportion of adverse reactions was generally higher after the second vaccination and decreased with each additional vaccination. No statistically significant differences in the adverse reactions were found for males and females and those with/without a history of allergy, but a lower proportion of fever was observed in older participants and those with underlying medical conditions. We also evaluated the association between adverse reactions and antibody titers after the third vaccination and found no significant differences in antibody levels one month after vaccination. This series of studies highlights the importance of conducting surveys in diverse populations to provide a more representative picture of post-vaccination adverse reactions during a pandemic.
キーワード coronavirus disease 2019 adverse reactions mRNA vaccine antibody titers young adults
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2023-12
巻 77巻
号 6号
出版者 Okayama University Medical School
開始ページ 567
終了ページ 575
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38145930
Web of Science KeyUT 001164631200001
フルテキストURL fulltext20231216-01.pdf suppl20231216-01.pdf
著者 Hagiyama, Akikazu| Sugimoto, Seiichiro| Tanaka, Shin| Matsubara, Kei| Miyoshi, Kentaroh| Katayama, Yoshimi| Hamada, Masanori| Senda, Masuo| Toyooka, Shinichi|
キーワード computed tomography lung transplantation prognosis skeletal muscle waiting time
備考 This is the peer reviewed version of the following article: [Hagiyama A, Sugimoto S, Tanaka S, et al. Impact of changes in skeletal muscle mass and quality during the waiting time on outcomes of lung transplantation. Clin Transplant. 2024; 38:e15169. https://doi.org/10.1111/ctr.15169], which has been published in final form at [https://doi.org/10.1111/ctr.15169]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Oct. 2024.|
発行日 2023-10-26
出版物タイトル Clinical Transplantation
巻 38巻
号 1号
出版者 Wiley
開始ページ e15169
ISSN 0902-0063
NCID AA10694240
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 John Wiley & Sons A/S.
論文のバージョン publisher
PubMed ID 37882504
DOI 10.1111/ctr.15169
Web of Science KeyUT 001087097300001
関連URL isVersionOf https://doi.org/10.1111/ctr.15169
フルテキストURL K0006907_abstract_review.pdf K0006907_fulltext.pdf K0006907_summary.pdf
著者 藤井 健人|
発行日 2023-09-25
資料タイプ 学位論文
学位授与番号 甲第6907号
学位授与年月日 2023-09-25
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
著作権者 © 2023 John Wiley & Sons A/S.
フルテキストURL fulltext.pdf
著者 Toyosawa, Junki| Yamasaki, Yasushi| Fujimoto, Tsuyoshi| Tanaka, Shouichi| Tanaka, Takehiro| Mitsuhashi, Toshiharu| Okada, Hiroyuki|
発行日 2022-05-13
出版物タイトル Endoscopy International Open
巻 10巻
号 05号
出版者 Georg Thieme Verlag KG
開始ページ E602
終了ページ E608
ISSN 2364-3722
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022. The Author(s).
論文のバージョン publisher
PubMed ID 35571476
DOI 10.1055/a-1785-8616
Web of Science KeyUT 000794976400009
関連URL isVersionOf https://doi.org/10.1055/a-1785-8616
フルテキストURL fulltext20231110-02.pdf
著者 Hasegawa, Kosei| Futagawa, Natsuko| Ago, Yuko| Miyahara, Hiroyuki| Harada, Daisuke| Miyazawa, Mari| Yoshimoto, Junko| Baba, Kenji| Moriwake, Tadashi| Tanaka, Hiroyuki| Tsukahara, Hirokazu|
キーワード infant skeleton spine cartilage growth
発行日 2023
出版物タイトル Clinical Pediatric Endocrinology
巻 32巻
号 4号
出版者 Japanese Society for Pediatric Endocrinology
開始ページ 221
終了ページ 227
ISSN 0918-5739
NCID AA11006467
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 by The Japanese Society for Pediatric Endocrinology
論文のバージョン publisher
PubMed ID 37842142
DOI 10.1297/cpe.2023-0035
Web of Science KeyUT 001085272200003
関連URL isVersionOf https://doi.org/10.1297/cpe.2023-0035
フルテキストURL fulltext.pdf
著者 Otani, Yusuke| Yoshikawa, Soichiro| Nagao, Kei| Tanaka, Takehiro| Toyooka, Shinichi| Fujimura, Atsushi|
キーワード Mast cells Connective tissue mast cells Noradrenaline Immunoelectron microscopy SLC22A3
備考 The version of record of this article, first published in The Journal of Physiological Sciences, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12576-023-00883-3|
発行日 2023-10-12
出版物タイトル The Journal of Physiological Sciences
巻 73巻
号 1号
出版者 BMC
開始ページ 24
ISSN 1880-6546
NCID AA12129145
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023.
論文のバージョン publisher
PubMed ID 37828465
DOI 10.1186/s12576-023-00883-3
Web of Science KeyUT 001089236900002
関連URL isVersionOf https://doi.org/10.1186/s12576-023-00883-3
フルテキストURL fulltext20231030-01.pdf fig20231030-01.pdf table20231030-01.pdf suppl20231030-01.pdf
著者 Kakiuchi, Yoshihiko| Kuroda, Shinji| Choda, Yasuhiro| Otsuka, Shinya| Ueyama, Satoshi| Tanaka, Norimitsu| Muraoka, Atsushi| Hato, Shinji| Kamikawa, Yasuaki| Fujiwara, Toshiyoshi|
キーワード Double -flap technique Gastric cancer Prognostic factor Prognostic nutritional index Proximal gastrectomy
備考 © 2023 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Sep. 2024.|
発行日 2023-10
出版物タイトル Surgical Oncology
巻 50巻
出版者 Elsevier BV
開始ページ 101990
ISSN 0960-7404
NCID AA10850448
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 Elsevier Ltd.
論文のバージョン author
PubMed ID 37717376
DOI 10.1016/j.suronc.2023.101990
Web of Science KeyUT 001082185900001
関連URL isVersionOf https://doi.org/10.1016/j.suronc.2023.101990
フルテキストURL fulltext20231025-02.pdf
著者 Tanaka, Atsuko| Hayano, Satoru| Nagata, Masayo| Kosami, Takahiro| Wang, Ziyi| Kamioka, Hiroshi|
キーワード Type-I interferon Janus kinase/signal transducers and activators of transcription pathway Osteoblast Necroptosis Singleton-Merten Syndrome
発行日 2023-11
出版物タイトル Archives of Oral Biology
巻 155巻
出版者 Elsevier BV
開始ページ 105797
ISSN 0003-9969
NCID AA00548457
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 The Author(s).
論文のバージョン publisher
PubMed ID 37633030
DOI 10.1016/j.archoralbio.2023.105797
Web of Science KeyUT 001069097000001
関連URL isVersionOf https://doi.org/10.1016/j.archoralbio.2023.105797
JaLCDOI 10.18926/AMO/65978
フルテキストURL 77_5_545.pdf
著者 Iwamuro, Masaya| Tanaka, Shouichi| Toyokawa, Tatsuya| Nishimura, Mamoru| Tsuzuki, Takao| Miyahara, Koji| Negishi, Shin| Ohya, Shogen| Tanaka, Takehiro| Otsuka, Motoyuki|
抄録 To determine the endoscopic and clinical features of localized gastric amyloid light-chain (AL) amyloidosis, we retrospectively examined the characteristics of nine patients (eight men and one woman) encountered by the hospitals in our network. Lesions were predominantly flat and depressed with surface vascular dilatation (n=5); others were characterized by subepithelial lesions (n=2), mucosal color change (n=1), and a mass-like morphology with swollen mucosal folds (n=1). Colonoscopy (n=7), video capsule enteroscopy (n=2), serum (n=5) and urine immunoelectrophoresis (n=4), and bone marrow examination (n=3) were performed to exclude involvement of organs other than the stomach. As treatment for gastric lesions of AL amyloidosis, one patient each underwent endoscopic submucosal dissection (n=1) and argon plasma coagulation (n=1), while the remaining seven patients underwent no specific treatment. During a mean follow-up of 4.2 years, one patient died 3.2 years after diagnosis, but the cause of death, which occurred in another hospital, was unknown. The remaining eight patients were alive at the last visit. In conclusion, although localized gastric AL amyloidosis can show various macroscopic features on esophagogastroduodenoscopy, flat, depressed lesions with vascular dilatation on the surface are predominant.
キーワード esophagogastroduodenoscopy gastric lesion amyloidosis light chain
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
巻 77巻
号 5号
出版者 Okayama University Medical School
開始ページ 545
終了ページ 552
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899266
Web of Science KeyUT 001094245100001
JaLCDOI 10.18926/AMO/65975
フルテキストURL 77_5_527.pdf
著者 Ando, Miho| Hanayama, Yoshihisa| Nishimura, Yoshito| Hagiya, Hideharu| Otsuka, Fumio|
抄録 Retroperitoneal fibrosis (RPF) is a rare cause of hydronephrosis and progressive renal dysfunction with unidentified origin. RPF is categorized into idiopathic RPF with/without immunoglobulin G4 (IgG4)-related disease (IgG4-RD), and secondary RPF. Identifying the underlying cause is challenging and often associated with delayed diagnosis or therapeutic interventions. We investigated RPF’s clinical characteristics based on different etiologies and factors that may help distinguish the underlying causes. We analyzed the cases of 49 patients with RPF that was radiographically diagnosed at our institution (2008-2022). The cohort was 77.6% males; 75.5% had idiopathic RPF and 24.5% had secondary RPF. Among the idiopathic patients, 54.1% had IgG4-RD. The patients were likely to have abdominal pain, lower back pain/lumbago, and constitutional symptoms including generalized fatigue and fever. The idiopathic patients were likely to have higher serum IgG4 and IgG levels and lower serum C3 levels compared to secondary RPF. The IgG4-RPF patients were likely to have higher serum IgG4 levels and lower serum C-reactive protein, ferritin, and C3 levels compared to the idiopathic RPF patients without IgG4-RD. These findings might reflect underlying systemic inflammatory responses. Comprehensive laboratory testing, including serum inflammatory markers and immunological panels, is recommended for radiologically diagnosed RPF patients.
キーワード retroperitoneal fibrosis IgG4-related disease malignancy
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
巻 77巻
号 5号
出版者 Okayama University Medical School
開始ページ 527
終了ページ 536
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899264
Web of Science KeyUT 001108661600010
JaLCDOI 10.18926/AMO/65973
フルテキストURL 77_5_511.pdf
著者 Sato, Kohei| Tsuji, Hironori| Yorimitsu, Masanori| Uehara, Takenori| Okazaki, Yuki| Takao, Shinichiro| Hata, Toshiaki| Fukuoka, Shiro| Noda, Tomoyuki| Kanda, Hideyuki| Ozaki, Toshifumi|
抄録 Sarcopenia and malnutrition are increasing in older adults and are reported risk factors for functional impairment after hip fracture surgery. This study aimed to investigate the associations between skeletal muscle mass loss, malnutrition, and postoperative walking ability in patients with hip fracture. We retrospectively reviewed patients who underwent intertrochanteric fracture surgery at our institute. The psoas muscle index, controlling nutritional status score, and functional ambulation category (FAC) were used to evaluate skeletal muscle mass, nutritional status, and walking ability, respectively. Six months after surgery, walking ability was assessed as either “gait disturbance” or “independent gait”. Multivariate binomial logistic regression analysis, with skeletal muscle mass, nutritional status, and other factors, was used to predict the risk of being assigned to the gait disturbance group. This study included 95 patients (mean age, 85.2 years; 70 women). Sixty-six patients had low skeletal muscle mass, 35 suffered from malnutrition, and 28 had both. Malnutrition and low skeletal muscle mass were significantly associated with postoperative gait disturbance (FAC < 3). Preoperative low skeletal muscle mass and malnutrition were risk factors for postoperative poor walking ability. Further preventive interventions focusing on skeletal muscle mass and nutritional status are required.
キーワード sarcopenia nutrition geriatric hip fracture psoas muscle index controlling nutritional status score
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
巻 77巻
号 5号
出版者 Okayama University Medical School
開始ページ 511
終了ページ 516
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899262
Web of Science KeyUT 001108661600008
JaLCDOI 10.18926/AMO/65972
フルテキストURL 77_5_499.pdf
著者 Hatakeyama, Yuji| Hongo, Michio| Kido, Tadato| Urayama, Masakazu| Kasukawa, Yuji| Sasaki, Hiroshi| Aizawa, Toshiaki| Kudo, Daisuke| Kimura, Ryota| Ono, Yuichi| Kasama, Fumihito| Miyakoshi, Naohisa|
抄録 This study aimed to clarify neurological differences among the epiconus, conus medullaris, and cauda equina syndromes. Eighty-seven patients who underwent surgery for acute thoracolumbar spinal injuries were assessed. We defined the epiconus as the region from the terminal end of the spinal cord to the proximal 1.0 to 2.25 vertebral bodies, the conus medullaris as the region proximal to < 1.0 vertebral bodies, and the cauda equina as the distal part of the nerve roots originating from the spinal cord. On the basis of the distance from the terminal end of the spinal cord to the narrowest level of the spinal canal, the narrowest levels were ordered as follows: the epiconus followed by the conus medullaris and cauda equina. The narrowest levels were the epiconus in 22 patients, conus medullaris in 37 patients, and cauda equina in 25 patients. On admission, significantly more patients had a narrowed epiconus of Frankel grades A-C than a narrowed cauda equina. At the final follow-up, there were no significant differences in neurological recovery among those with epiconus, conus medullaris, or cauda equina syndrome. Anatomically classifying the narrowest lesion is useful for clarifying the differences and similarities among these three syndromes.
キーワード thoracolumbar spinal injury terminal end of spinal cord conus medullaris epiconus syndrome cauda equina syndrome
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
巻 77巻
号 5号
出版者 Okayama University Medical School
開始ページ 499
終了ページ 509
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899261
Web of Science KeyUT 001108661600007
JaLCDOI 10.18926/AMO/65970
フルテキストURL 77_5_479.pdf
著者 Murata, Akiko| Matsumoto, Naomi| Miyaji, Chikara| Takao, Soshi| Yorifuji, Takashi|
抄録 For decades, the notion has persisted in developed countries that exclusive care by the mothers is best for the development of children up to 3 years of age. To examine the veracity of this “myth of the first three years” in Japan, we examined the effects of childcare facility use for children younger than 3 years on their development using the cohorts of the Longitudinal Survey of Newborns in the 21st Century conducted in Japan. Of the 47,015 respondents to the survey, we studied the children of 5,508 mothers with university/professional education to evaluate the relationships between primary early (< 2.5 years) childcare providers during weekday daytime hours and specific development indices for the ages of 2.5, 5.5, and 8 years. At the age of 2.5 and 5.5 years, children attending childcare facilities were judged as having more advanced developmental behaviors by their parents, such as being able to compose a two-word sentence (adjusted odds ratio [aOR]: 0.22) or to express emotions (aOR: 0.81), compared with those cared for by mothers. However, at the age of 8 years, children who attended childcare facilities as infants < 2.5 years showed more aggressive behavior in interrupting people (aOR: 1.20) and causing disturbances in public (aOR: 1.26) than those cared for by mothers (after adjustment for numerous child and parental factors). Although these results are generally consistent with previous studies, issues potentially involved with problem behavior such as quality of childcare require further investigation, as does the case of children of mothers with more modest educational attainment.
キーワード “myth of the first three years” childcare child development problem behavior educational attainment
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
巻 77巻
号 5号
出版者 Okayama University Medical School
開始ページ 479
終了ページ 490
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899259
Web of Science KeyUT 001108661600005
JaLCDOI 10.18926/AMO/65969
フルテキストURL 77_5_471.pdf
著者 Oka, Shohei| Harada, Keita| Yamamoto, Shumpei| Yasutomi, Eriko| Igawa, Shoko| Ohmori, Masayasu| Hirai, Mami| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Hiraoka, Sakiko| Okada, Hiroyuki|
抄録 Although the clinical usefulness of colonoscopy has been established, the procedure remains painful for many patients. This study was designed to clarify the factors predicting colonoscopy-related pain. We evaluated 283 consecutive patients who completed a first-ever, total colonoscopy without sedatives or analgesics. The severity of pain symptoms was evaluated by a numeric rating scale (NRS) in a questionnaire immediately after the colonoscopy. Patient backgrounds and endoscopic findings were analyzed to evaluate their association with pain. Out of 283 patients, 53 scored their pain 0-1 on the NRS while 48 scored it 6-10. We defined the colonoscopies of the former and latter patients as painless and painful, respectively, and compared the two. Multivariate analyses revealed that low body weight (OR 4.95, 95%CI 1.89-12.99) and longer intubation time (OR 3.63, 95%CI 1.46-9.03) were significant risk factors for painful colonoscopy. To identify factors contributing to the increased intubation time, we divided subjects into short- and long-intubation-time groups based on a median insertion time of 7 min. Older age (OR 2.28, 95%CI 1.31-3.98), previous abdominal surgery (OR 1.93, 95%CI 1.13-3.32) and findings of invasive cancer (OR 10.90, 95%CI 1.34-88.90) were significant factors for longer intubation time.
キーワード colonoscopy colonoscopy-related pain comfortable colonoscopy
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
巻 77巻
号 5号
出版者 Okayama University Medical School
開始ページ 471
終了ページ 478
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899258
Web of Science KeyUT 001108661600004
JaLCDOI 10.18926/AMO/65966
フルテキストURL 77_5_443.pdf
著者 Miyaji, Chikara| Takao, Soshi| Habu, Hiroshi| Matsumoto, Naomi| Aoo, Ken| Nishita, Yosuke| Tsuri, Masao| Yorifuji, Takashi|
抄録 This study examined whether participation in an art project was associated with higher social capital (SC). We conducted a questionnaire survey from November 2021 to March 2022 among residents aged 20 years or older of Naoshima, an island in Kagawa Prefecture, Japan. Before the survey, the Setouchi Triennale had been held on Naoshima four times, starting in 2010. We calculated propensity scores for Triennale participation and performed propensity score matching. We then compared cognitive and structural SC by Triennale participation and found significant differences, respectively. We adopted a conditional ordered logistic regression analysis with propensity score matching for cognitive or structural SC, and found adjusted odd ratios of 2.913 (95%CI, 1.846-4.596) for cognitive SC and 4.535 (95%CI, 2.839-7.244) for structural SC. Our findings suggest that Triennale participation enhanced the cognitive aspect of SC while also building structural SC.
キーワード social capital art project propensity score matching
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
巻 77巻
号 5号
出版者 Okayama University Medical School
開始ページ 443
終了ページ 449
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899255
Web of Science KeyUT 001108661600001