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タイトル(別表記) Acquired idiopathic generalized anhidrosis (AIGA)
著者 川上 佳夫|
キーワード コリン性蕁麻疹 ステロイドパルス 機能性高体温症
出版物タイトル 岡山医学会雑誌
発行日 2024-08-01
巻 136巻
号 2号
開始ページ 74
終了ページ 76
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.136.74
言語 日本語
著作権者 Copyright (c) 2024 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.136.74
タイトル(別表記) A case of immune checkpoint inhibitor-associated colitis treated with infliximab
著者 岩室 雅也| 平岡 佐規子| 大塚 基之|
抄録  A 52-year-old Japanese man diagnosed with non-small cell lung cancer initiated chemotherapy with tremelimumab, durvalumab, nanoparticle albumin-bound paclitaxel, and carboplatin. On the fourth day of the first treatment course, he developed a fever, followed by watery diarrhea exceeding 10 episodes per day and bloody stools the next day. Immunotherapy-related adverse event colitis was diagnosed through CT scans and colonoscopy examinations. Despite the ineffectiveness of systemic steroid administration, prompt alleviation of symptoms was achieved through the administration of infliximab. In our case, the patient developed Grade 3 diarrhea, prompting the initiation of intravenous prednisolone at 80mg/day in accordance with guidelines. However, symptom improvement was not attained. In situations where symptoms persist beyond three days despite systemic steroid administration, the consideration of adjunctive infliximab use at a dosage of 5mg/kg becomes necessary.
キーワード インフリキシマブ(infliximab) 免疫関連有害事象(immune-related adverse events) 大腸炎(colitis)
出版物タイトル 岡山医学会雑誌
発行日 2024-08-01
巻 136巻
号 2号
開始ページ 69
終了ページ 73
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.136.69
言語 日本語
著作権者 Copyright (c) 2024 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.136.69
タイトル(別表記) Metformin-induced mitochondrial reactive oxygen species and host defense mechanisms
著者 鵜殿 平一郎|
キーワード CD8T 細胞 活性酸素 Nrf2 解糖系 ミトコンドリア
出版物タイトル 岡山医学会雑誌
発行日 2024-08-01
巻 136巻
号 2号
開始ページ 63
終了ページ 68
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.136.63
言語 日本語
著作権者 Copyright (c) 2024 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.136.63
タイトル(別表記) Five-year findings from the home blood pressure management study using IoT technology and future perspectives based on a time-series big data and AI analysis : the Masuda Study
著者 久松 隆史| 絹田 皆子| 福田 茉莉| 谷口 かおり| 中畑 典子| 神田 秀幸|
キーワード 家庭血圧(home blood pressure) IoT AI ビックデータ(big data)
出版物タイトル 岡山医学会雑誌
発行日 2024-08-01
巻 136巻
号 2号
開始ページ 57
終了ページ 62
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.136.57
言語 日本語
著作権者 Copyright (c) 2024 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.136.57
タイトル(別表記) The 2023 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2023 Sunada Prize)
著者 松原 慧|
出版物タイトル 岡山医学会雑誌
発行日 2024-08-01
巻 136巻
号 2号
開始ページ 54
終了ページ 56
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.136.54
言語 日本語
著作権者 Copyright (c) 2024 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.136.54
タイトル(別表記) The 2023 Incentive Award of the Okayama Medical Association in Neuroscience (2023 Niimi Prize)
著者 藪野 諭|
出版物タイトル 岡山医学会雑誌
発行日 2024-08-01
巻 136巻
号 2号
開始ページ 51
終了ページ 53
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.136.51
言語 日本語
著作権者 Copyright (c) 2024 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.136.51
タイトル(別表記) The 2023 Incentive Award of the Okayama Medical Association in General Medical Science (2023 Yuuki Prize)
著者 内藤 宏道|
出版物タイトル 岡山医学会雑誌
発行日 2024-08-01
巻 136巻
号 2号
開始ページ 48
終了ページ 50
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.136.48
言語 日本語
著作権者 Copyright (c) 2024 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.136.48
タイトル(別表記) The 2023 Incentive Award of the Okayama Medical Association in Cancer Research (2023 Hayashibara Prize and Yamada Prize)
著者 石野 貴雅|
出版物タイトル 岡山医学会雑誌
発行日 2024-08-01
巻 136巻
号 2号
開始ページ 45
終了ページ 47
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.136.45
言語 日本語
著作権者 Copyright (c) 2024 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.136.45
フルテキストURL fulltext20240822-01.pdf
著者 Kawase, Tomoka| Miura, Fumi| Debnath, Anusuya| Imakura, Kinuyo| Miyoshi, Shin-ichi|
キーワード Vibrio vulnificus Protease Propeptide Domain Cell-free translational system
備考 © 2018 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/|
発行日 2018-09
出版物タイトル Protein Expression and Purification
巻 149巻
出版者 Elsevier BV
開始ページ 13
終了ページ 16
ISSN 1046-5928
NCID AA10814149
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2018 Elsevier Inc.
論文のバージョン author
PubMed ID 29635038
DOI 10.1016/j.pep.2018.04.004
Web of Science KeyUT 000434003700003
関連URL isVersionOf https://doi.org/10.1016/j.pep.2018.04.004
フルテキストURL fulltext.pdf
著者 Sumi, Tomonari| Harada, Kouji|
キーワード post-acute sequelae of SARS-CoV-2 infection PASC long Covid persistent viruses vaccine antiviral drug mathematical model immune response
発行日 2024-08-09
出版物タイトル Frontiers in Immunology
巻 15巻
出版者 Frontiers Media
開始ページ 1329162
ISSN 1664-3224
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 Sumi and Harada.
論文のバージョン publisher
PubMed ID 39185419
DOI 10.3389/fimmu.2024.1329162
Web of Science KeyUT 001295899400001
関連URL isVersionOf https://doi.org/10.3389/fimmu.2024.1329162
フルテキストURL fulltext.pdf
著者 Fukao, Takashi| Fujiwara, Masaki| Yamada, Yuto| Sakamoto, Shinji| Matsumoto, Yosuke| Takaki, Manabu|
キーワード anti-seizure medications attention-deficit/hyperactivity disorder electroencephalography transient epileptic amnesia
発行日 2024-08-22
出版物タイトル Psychiatry and Clinical Neurosciences Reports
巻 3巻
号 3号
出版者 Wiley
開始ページ e70003
ISSN 2769-2558
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 The authors.
論文のバージョン publisher
PubMed ID 39184058
DOI 10.1002/pcn5.70003
Web of Science KeyUT 001295703300001
関連URL isVersionOf https://doi.org/10.1002/pcn5.70003
フルテキストURL fulltext.pdf
著者 Ueda, Masataka| Tetsunaga, Tomoko| Tetsunaga, Tomonori| Nishida, Keiichiro| Takatori, Ryo| Shitozawa, Hisakazu| Uotani, Koji| Shinohara, Kennsuke| Oda, Yoshiaki| Ozaki, Toshifumi|
キーワード AIS cognitive-behavioral therapy EQ5D HADS insomnia pain-liaison outpatient clinic sleep disorders
発行日 2024-08-09
出版物タイトル Medicine
巻 103巻
号 32号
出版者 Lippincott, Williams & Wilkins
開始ページ e39113
ISSN 0025-7974
NCID AA00728867
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 the Author(s).
論文のバージョン publisher
PubMed ID 39121265
DOI 10.1097/MD.0000000000039113
Web of Science KeyUT 001287977800045
関連URL isVersionOf https://doi.org/10.1097/MD.0000000000039113
JaLCDOI 10.18926/AMO/67554
フルテキストURL 78_4_349.pdf
著者 Tominaga, Yuichiro| Sugaya, Akiko| Kariya, Shin| Shimizu, Aiko| Kataoka, Yuko| Ando, Mizuo|
抄録 Middle-ear salivary gland choristoma (SGCh) is a rare, benign tumor that causes conductive hearing loss owing to middle-ear morphological abnormalities. Early diagnosis is challenging, and surgical resection is indispensable for a definitive diagnosis. We report the case of a 3-year-old boy diagnosed with middle-ear SGCh during the follow-up period for left-sided hearing loss discovered at newborn hearing screening (NHS). Long-term follow-up after the NHS result, subsequent computed tomography/magnetic resonance imaging, and surgical resection led to its relatively early diagnosis and treatment.
キーワード middle-ear salivary gland choristoma middle-ear morphological abnormalities newborn hearing screening unilateral hearing loss surgical resection
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2024-08
巻 78巻
号 4号
出版者 Okayama University Medical School
開始ページ 349
終了ページ 355
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 39198990
Web of Science KeyUT 001310557400004
JaLCDOI 10.18926/AMO/67553
フルテキストURL 78_4_345.pdf
著者 Kato, Gentaro| Narumiya, Yuto| Okuyama, Michihiro| Shimizu, Shuji| Sangawa, Kenji| Yamamoto, Shu|
抄録 The presence of an intraperitoneal source of infection, e.g., a liver abscess, can be an obstacle to performing an abdominal aortic surgery with a midline laparotomy because graft infection is one of the most critical complications of aortic surgery. We report the successful Y-grafting of a pararenal abdominal aortic aneurysm through a retroperitoneal approach in a 67-year-old male undergoing liver abscess drainage. The retroperitoneal approach to the abdominal aorta may be useful for abdominal aortic surgery in patients with a localized intraperitoneal infection.
キーワード blunt liver trauma liver abscess abdominal aortic aneurysm Y-grafting retroperitoneal approach
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2024-08
巻 78巻
号 4号
出版者 Okayama University Medical School
開始ページ 345
終了ページ 347
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 39198989
Web of Science KeyUT 001310557400003
JaLCDOI 10.18926/AMO/67550
フルテキストURL 78_4_337.pdf
著者 Makihara, Seiichiro| Otani, Yoshihiro| Uraguchi, Kensuke| Ono, Sawako| Shimizu, Aiko| Ikemachi, Ryosuke| Okazaki, Yosuke| Ota, Tomoyuki| Matsumoto, Hiroshi| Miyamoto, Shotaro| Tsumura, Munechika| Hayashi, Seiya| Umakoshi, Michiari| Hirashita, Koji| Ando, Mizuo|
抄録 Here, we describe the unique case of a pneumocephalus originating from an inverted papilloma (IP) in the frontoethmoidal sinus. A 71-year-old man with diabetes presented with headaches and altered consciousness. Imaging revealed the pneumocephalus together with bone destruction in the left frontal sinus. He underwent simultaneous endoscopic endonasal and transcranial surgery using an ORBEYE exoscope. Pathological diagnosis of the tumor confirmed IP. Post-surgery, the pneumocephalus was significantly resolved and the squamous cell carcinoma antigen level, which had been elevated, decreased. This case underscores the importance of a multidisciplinary approach and innovative surgical methods in treating complex sinonasal pathologies.
キーワード pneumocephalus inverted papilloma frontoethmoidal sinus endoscopic endonasal and transcranial surgery
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2024-08
巻 78巻
号 4号
出版者 Okayama University Medical School
開始ページ 337
終了ページ 343
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 39198988
Web of Science KeyUT 001310557400002
JaLCDOI 10.18926/AMO/67549
フルテキストURL 78_4_331.pdf
著者 Furukawa, Chieko| Tachibana, Tomoyasu| Nobuhisa, Tetsuji| Kanie, Yuichiro| Wani, Yoji| Matsumoto, Jun-Ya| Kariya, Akifumi| Sato, Asuka| Ishikawa, Iichiro| Naoi, Yuto| Ando, Mizuo|
抄録 No previous study has published magnetic resonance imaging (MRI) findings for a subglottic pleomorphic adenoma. Here, we describe the case of a 62-year-old man with a subglottic pleomorphic adenoma. Endoscopic findings revealed a smooth-surfaced tumor arising from the subglottic posterior wall. MRI revealed the lesion as an isointense region on T1-weighted images, which was homogeneously enhanced. This lesion showed a heterogeneously hyperintense region on T2-weighted images. Diffusion-weighted imaging (DWI) showed slightly high intensity in the same area, with a normal or only slightly high apparent diffusion coefficient (ADC). Laryngomicrosurgery was performed for transoral excision of the subglottic tumor, resulting in a postsurgical diagnosis of pleomorphic adenoma.
キーワード subglottis pleomorphic adenoma MRI transoral surgery
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2024-08
巻 78巻
号 4号
出版者 Okayama University Medical School
開始ページ 331
終了ページ 335
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 39198987
Web of Science KeyUT 001310557400001
JaLCDOI 10.18926/AMO/67548
フルテキストURL 78_4_323.pdf
著者 Katayama, Akira| Kimura, Satoshi| Matsusaki, Takashi| Morimatsu, Hiroshi|
抄録 It has not been clear how recipient age affects the incidence of serious complications after pediatric living donor liver transplantation (LDLT). We investigated the records of 42 pediatric patients receiving LDLT, dividing our sample into two groups: the infant group (aged < 1 year) and the non-infant group (aged ≥ 1 year and ≤15 years). The primary outcome was postoperative complications assessed using the Clavien-Dindo classification. Multivariate analysis using the Cox regression model was applied to adjust for confounding factors in assessing the incidence of Clavien-Dindo grade ≥ III (C-D ≥ III) complications. The incidence of C-D ≥ III complications was higher in the non-infant group (46.2%) than in the infant group (12.5%) (odds ratio 6.00, 95% confidence interval [CI] 1.13-31.88, p=0.03). In multivariate analysis using the Cox regression model, the Graft-to-Recipient Weight Ratio (GRWR) was independently associated with the incidence of C-D ≥ III complications (hazard ratio [HR] 0.62, 95%CI 0.40-0.95, p=0.03), but being an infant was not (HR 0.84, 95%CI 0.35-1.98, p=0.68). In conclusion, the incidence of C-D ≥ III complications was higher in the non-infant group than in the infant group, but this was largely a function of GRWR: multivariate analysis revealed that GRWR was independently associated with complications.
キーワード pediatric liver transplantation postoperative severe complications Graft-to-Recipient Weight Ratio
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2024-08
巻 78巻
号 4号
出版者 Okayama University Medical School
開始ページ 323
終了ページ 330
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 39198986
Web of Science KeyUT 001310576400003
JaLCDOI 10.18926/AMO/67547
フルテキストURL 78_4_313.pdf
著者 Eto, Eriko| Maki, Jota| Yamashita, Noriyuki| Hasegawa, Toru| Suemori, Ayano| Nakato, Hikari| Oba, Hikaru| Mitoma, Tomohiro| Mishima, Sakurako| Kirino, Satoe| Ohira, Akiko| Masuyama, Hisashi|
抄録 During the coronavirus pandemic, face-to-face simulation education became impossible. Therefore, we aimed to develop remote-access simulation education with a sense of realism through Information and Communication Technology (ICT) using a perinatal whole-body management and delivery simulator. In September 2021, we administered a multi-center simultaneous remote simulation based on our developed model. Ten universities in the Chugoku–Shikoku region were connected via a web-conferencing system to a live broadcast of a virtual vaginal birth in which a fictional hospitalized pregnant woman experienced accelerated labor and gave birth through vacuum delivery for fetal distress. A Video on Demand (VOD) was made beforehand using a new simulator that allowed for a visual understanding of the process of the inter-vaginal examination. We provided a participatory program that enhanced the sense of realism by combining VOD and real-time lectures on each scenario, with two-way communication between participants and trainee doctors using a chat function. Most participants answered “satisfied” or “very satisfied” with the content, level of difficulty, and level of understanding. From November 2021, we have used the videos of all processes in face-to-face classes. Our construction of a high-flexibility education system using remote simulation in the field of obstetrics and gynecology, especially in the vaginal delivery module, is unique, creative, and sustainable.
キーワード remote simulator education perinatal simulator information and communication technology high-flexibility education
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2024-08
巻 78巻
号 4号
出版者 Okayama University Medical School
開始ページ 313
終了ページ 322
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 39198985
Web of Science KeyUT 001310576400002
JaLCDOI 10.18926/AMO/67546
フルテキストURL 78_4_307.pdf
著者 Sugihara, Naoya| Hashine, Katsuyoshi| Yamashita, Natsumi| Sakamoto, Miki| Terashita, Masato| Funaki, Keisuke| Saiki, Kaori| Sawada, Takatora| Kakuda, Toshio| Nishimura, Kenichi| Fukumoto, Tetsuya| Miura, Noriyosi| Miyauchi, Yuki| Kikugawa, Tadahiko| Saika, Takashi|
抄録 The Briganti nomogram (cut-off value 5%) is commonly used to determine the indications for pelvic lymph node dissection (PLND) in patients with prostate cancer. We retrospectively analyzed the potential oncological benefit of PLND based on the 5% cut-off value on the Briganti nomogram. We obtained the data from the Medical Investigation Cancer Network (MICAN) Study, which included 3,463 patients who underwent a radical prostatectomy (RP) at nine institutions in Japan between 2010 and 2020. We included patients with Briganti scores ≥ 5% and a follow-up period ≥6 months and excluded patients categorized in the very high-risk group (based on NCCN categories); a final total of the cases of 1,068 patients were analyzed. The biochemical recurrence (BCR)-free survival was significantly worse in the patients who underwent PLND compared to those who did not (p=0.019). A multivariate analysis showed that high prostate-specific antigen (PSA) levels (p<0.001) and an advanced T-stage (p=0.018) were significant prognostic factors for BCR, whereas PLND had no effect on BCR (p=0.059). Thus, PLND in patients with prostate cancer whose Briganti score was 5% did not provide any oncological benefit. Further research is necessary to determine the indication criteria for conducting PLND.
キーワード Briganti nomogram pelvic lymph node dissection prostate cancer radical prostatectomy
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2024-08
巻 78巻
号 4号
出版者 Okayama University Medical School
開始ページ 307
終了ページ 312
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 39198984
Web of Science KeyUT 001310576400001
フルテキストURL fulltext.pdf
著者 Yokota, Osamu| Miki, Tomoko| Nakashima-Yasuda, Hanae| Ishizu, Hideki| Haraguchi, Takashi| Ikeda, Chikako| Hasegawa, Masato| Miyashita, Akinori| Ikeuchi, Takeshi| Nishikawa, Naoto| Takenoshita, Shintaro| Sudo, Koichiro| Terada, Seishi| Takaki, Manabu|
キーワード Argyrophilic grain Globus pallidus Hippocampal sclerosis Striatum Substantia nigra Subthalamic nucleus
備考 The version of record of this article, first published in Acta Neuropathologica Communications, is available online at Publisher’s website: http://dx.doi.org/10.1186/s40478-024-01828-6|
発行日 2024-07-31
出版物タイトル Acta Neuropathologica Communications
巻 12巻
号 1号
出版者 BMC
開始ページ 121
ISSN 2051-5960
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2024.
論文のバージョン publisher
PubMed ID 39085955
DOI 10.1186/s40478-024-01828-6
Web of Science KeyUT 001281506800001
関連URL isVersionOf https://doi.org/10.1186/s40478-024-01828-6