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JaLCDOI 10.18926/AMO/61437
フルテキストURL 75_1_71.pdf
著者 Sanki, Tomoaki| Tetsunaga, Tomonori| Furumatsu, Takayuki| Yamada, Kazuki| Kawamura, Yoshi| Ozaki, Toshifumi|
抄録 Intra-operative acetabular fracture is a total hip arthroplasty complication that can occur during cementless cup insertion, especially in osteoporotic patients. We conducted this biomechanical study to investigate the impact resistance of the acetabulum with simulated bones of different density by drop-weight impact testing. Low- and high-density polyurethane foam blocks were used as osteoporotic and healthy bone models, respectively. Polyurethane blocks were used as the acetabular cancellous bone. Composite sheets were used as the acetabu-lum’s medial cortex. The testing revealed that the osteoporotic bone model’s impact resistance was significantly lower than that the healthy bone model’. In the healthy bone model, even thin acetabular cancellous bone with ≥ 1 mm acetabulum medial cortex was less likely to fracture. In the osteoporotic bone model, fracture was pos-sible without ≥ 1 mm medial cortex of the acetabulum and thick acetabular cancellous bone. Although impac-tion resistance differs due to bone quality, the impaction resistance in this osteoporotic bone model was equiv-alent to that healthy bone model’s when a thick medial wall was present. To avoid intra-operative acetabulum fracture, surgeons should consider both the bone quality and the thicknesses of the medial cortex and acetabu-lar cancellous bone.
キーワード intra-operative acetabular fracture drop weight impact testing total hip arthroplasty impact resistance
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 71
終了ページ 77
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649616
JaLCDOI 10.18926/AMO/61431
フルテキストURL 75_1_31.pdf
著者 Miyamaru, Satoru| Murakami, Daizo| Nishimoto, Kohei| Saito, Haruki| Miyamoto, Yusuke| Hirota, Kaoruko| Ise, Momoko| Orita, Yorihisa|
抄録 Although the lung is the most common site of distant metastases from head and neck squamous cell carcinoma (HNSCC), the number of reports about the effects of pulmonary metastasectomy for the treatment of lung metastasis from HNSCC is limited. Metachronous pulmonary metastases were detected in 45 HNSCC patients at Kumamoto University Hospital from 1998 to 2018. Twenty-two patients underwent an operative resection (Ope group) and 23 underwent chemotherapy (Chemo group). The 3-year overall survival (OS) rate and median OS were evaluated. The effects of adjuvant chemotherapy after pulmonary metastasectomy and of new drugs (cetuximab and nivolumab), in the chemo group were also assessed. The 3-year OS rates and median OS were: Ope, 66.1% and 31.5 months; Chemo, 39.7% and 18 months, respectively. In the Ope group, addi-tional recurrences were significantly fewer in the patients who underwent adjuvant chemotherapy post-surgery versus the patients who underwent surgery alone (p = 0.013). In the Chemo group, the 3-year OS rate of the patients who received new drugs was significantly better than that of the patients who did not (p = 0.021). Adjuvant chemotherapy after pulmonary metastasectomy may be a preferable treatment option for preventing recurrences. Cetuximab and nivolumab have a potential to improve OS.
キーワード pulmonary metastasis head and neck squamous cell carcinoma pulmonary metastasectomy adjuvant chemotherapy
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 31
終了ページ 37
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649611
JaLCDOI 10.18926/AMO/61430
フルテキストURL 75_1_25.pdf
著者 Tetsunaga, Tomonori| Tetsunaga, Tomoko| Yamada, Kazuki| Sanki, Tomoaki| Kawamura, Yoshi| Ozaki, Toshifumi|
抄録 In bipolar hemiarthroplasty (BHA), it is important to preserve soft tissue to reduce the risk of postoperative dislocation. A variety of surgical approaches for BHA are available, but extra care is needed with muscle- and tendon-preserving approaches in geriatric patients. We investigated the usefulness of BHA using a conjoined tendon-preserving posterior (CPP) approach, in which only the external obturator muscle is dissected, in geri-atric patients. We retrospectively analyzed the cases of 40 femoral neck fracture patients (10 men, 30 women) aged ≥ 80 years who underwent BHA using the CPP approach. The patients’ average age was 85.8 years (80-94 years). We examined the operation time, bleeding, preservation of short external rotator muscles, complica-tions, and stem alignment and subsidence from postoperative radiographs. Although gemellus inferior muscle injury was detected in 4 patients (10%), the hip joint stability was very excellent in all cases. There was no intraoperative fracture or postoperative dislocation. On postoperative radiographs, all femoral stems were in a neutral position. There was no stem subsidence in all 40 patients. BHA using the CPP approach appeared to be useful even in geriatric patients.
キーワード bipolar hip arthroplasty geriatric patient conjoined tendon-preserving posterior approach
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 25
終了ページ 30
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649610
JaLCDOI 10.18926/AMO/61428
フルテキストURL 75_1_9.pdf
著者 Gobara, Hideo| Yamamoto, Akira| Komakic, Toshiyuki| Kitayama, Toshiaki| Sakurai, Jun| Iguchi, Toshihiro| Matsui, Yusuke| Uka, Mayu| Tomita, Koji| Hiraki, Takao| Kanazawa, Susumu|
抄録 To assess the feasibility of needle tract ablation in liver tissue in ex vivo and in vivo animal models using a cryo-probe and electrosurgical device. The experimental device is made by inserting a cryoprobe through an intro-ducer sheath for insulation, with 2-cm of probe tip projecting out. A beagle liver was punctured by the device, and electric current was applied at 30-W with the electrosurgical knife touching the non-insulated device base. The discolored area of cut surface along the device was evaluated in 5 application-time groups (5 , 10 , 15 , 20, or 25 seconds). An ex vivo experiment was performed to determine an ablation algorithm with an appropriate application time by comparison with radiofrequency ablation (RFA) results. Thereafter, an in vivo experiment was performed to verify the algorithm’s feasibility. In the ex vivo model, the cut surface demonstrated different amounts of discolored area according to the application time. The total discolored area in the 20-seconds group was similar to that by RFA. In the in vivo model, the liver did not bleed, the total discolored area was similar to that ex vivo, and coagulation necrosis was confirmed by photomicrograph. Needle tract ablation can be per-formed using the experimental device and electrosurgical device.
キーワード needle tract ablation cryoablation electrosurgical device animal liver
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 9
終了ページ 14
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649608
JaLCDOI 10.18926/AMO/61424
フルテキストURL 75_1_1.pdf
著者 Hamahara, Jun| Honda, Hiroyuki| Yamamoto, Koichiro| Tokumasu, Kazuki| Hanayama, Yoshihisa| Hagiya, Hideharu| Obika, Mikako| Ueda, Keigo| Kishida, Masayuki| Otsuka, Fumio|
抄録 To determine the clinical characteristics of low androgen status in adult males with diabetes, we retrospectively analyzed the medical records of patients with type 2 diabetes mellitus in whom serum free testosterone (FT) levels were examined for 1 year. Among the 46 patients (56 ± 1.5 years old), decreases in serum FT levels to < 8.5 pg/ml (indicating the occurrence of late-onset hypogonadism [LOH]) were detected in 18 (39%). The per-centages of patients with low FT levels were high in the ≥ 50 years age group (83%), the HbA1c < 7% group (67%), and the 25 ≤ BMI < 30 kg/m2 group (56%). The serum FT levels tended to decrease age-dependently. The level of HbA1c was significantly correlated with the Heinemann Aging Male Symptoms (AMS) score (R = 0.47). The low-FT group had decreased levels of hemoglobin. Of note, the serum FSH level (R = −0.32) was negatively correlated with the serum FT level, whereas the serum TSH level (R = 0.36) was positively correlated with the serum FT level. Collectively, these results revealed that many diabetic males may have low FT levels and that the AMS score is related to the HbA1c level. A slightly anemic condition, thyroid dysfunction, and obesity (class 1) might be involved in LOH in middle-aged diabetic males.
キーワード androgen diabetes mellitus late-onset hypogonadism testosterone thyroid function
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 1
終了ページ 8
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649607
フルテキストURL fulltext.pdf figures.pdf
著者 Hiraoka, Hideki| Nomura, Ryosuke| Takasugi, Nobumasa| Akai, Ryoko| Iwawaki, Takao| Kumagai, Yoshito| Fujimura, Masatake| Uehara, Takashi|
キーワード Methylmercury Neuronal cell death ER stress UPR ERAI gene
備考 This is a post-peer-review, pre-copyedit version of an article published in Archives of Toxicology. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00204-021-02982-9.|
発行日 2021-01-16
出版物タイトル Archives of Toxicology
95巻
4号
出版者 Springer
開始ページ 1241
終了ページ 1250
ISSN 0340-5761
NCID AA00548865
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 33454823
DOI 10.1007/s00204-021-02982-9
Web of Science KeyUT 000608083700002
関連URL isVersionOf https://doi.org/10.1007/s00204-021-02982-9
フルテキストURL fulltext.pdf
著者 Nakano, Ryohei| Kawai, Takashi| Fukamatsu, Yosuke| Akita, Kagari| Watanabe, Sakine| Asano, Takahiro| Takata, Daisuke| Sato, Mamoru| Fukuda, Fumio| Ushijima, Koichiro|
キーワード fruit softening ethylene Prunus persica melting flesh locus endoPG postharvest
発行日 2020-11-26
出版物タイトル Frontiers in Plant Science
11巻
出版者 Frontiers Media
開始ページ 554158
ISSN 1664-462X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 Nakano, Kawai, Fukamatsu, Akita, Watanabe, Asano, Takata, Sato, Fukuda and Ushijima.
論文のバージョン publisher
PubMed ID 33324428
DOI 10.3389/fpls.2020.554158
Web of Science KeyUT 000596841900001
関連URL isVersionOf https://doi.org/10.3389/fpls.2020.554158
JaLCDOI 10.18926/AMO/61217
フルテキストURL 74_6_557.pdf
著者 Ishiguro, Mikako| Takenaka, Ryuta| Ogura, Kenichiro| Hiratsuka, Akira| Takeda, Hiromasa| Kawai, Daisuke| Tsugeno, Hirofumi| Fujiki, Shigeatsu| Okada, Hiroyuki|
抄録 A 63-year-old Japanese male with stomach adenocarcinoma received oral 5-fluorouracil derivative, cisplatin and trastuzumab chemotherapy. On day 8, severe diarrhea and mucositis developed; chemotherapy was stopped. On day 14, the patient developed renal dysfunction and febrile neutropenia. He also suffered from pneumonia due to Candida albicans. Systemic symptoms improved after intensive conservative treatment. Best supportive care was continued until the patient died from gastric cancer. The dihydropyrimidine dehydroge-nase protein level was low at 3.18 U/mg protein. The result of DPYD genotyping revealed three variants at posi-tions 1615 (G > A), 1627 (A > G), and 1896 (T > C) in exons 13, 13, and 14, respectively.
キーワード 5-fluorouracil dihydropyrimidine dehydrogenase deficiency DPYD variant gastric cancer
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2020-12
74巻
6号
出版者 Okayama University Medical School
開始ページ 557
終了ページ 562
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33361878
Web of Science KeyUT 000601203600014
NAID 120006948944
JaLCDOI 10.18926/AMO/61216
フルテキストURL 74_6_551.pdf
著者 Tanaka, Masato| Fujiwara, Yoshihiro| Uotani, Koji| Kadiri, Venkatesh| Yamauchi, Taro|
抄録 A minimally invasive posterolateral approach designed to avoid the lateral misplacement of midcervical pedicle screws was reported, but there is no technical report that describes this technique without C-arm fluoroscopy. We report the results of a 2.5 years follow-up of a 62-year-old female patient with C4 metastatic breast cancer. The patient suffered from severe neck pain and impending quadriplegia for 2 months after radiation therapy. We performed C-arm-free minimally invasive cervical pedicle screw fixation (MICEPS). The patient was suc-cessfully treated with surgery, and her neck pain was well controlled. She had neither neurological deficits nor neck pain at the final (2.5-year) follow-up. C-arm-free MICEPS is a useful technique; in addition, the sur-geons and staff have no risk of radiation exposure, there is a reduced need for postoperative imaging, and a decreased revision rate can be expected with C-arm-free MICEPS.
キーワード cervical spine navigation surgery minimally invasive surgery cervical pedicle screw C-arm free
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2020-12
74巻
6号
出版者 Okayama University Medical School
開始ページ 551
終了ページ 556
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33361877
Web of Science KeyUT 000601203600013
NAID 120006948943
JaLCDOI 10.18926/AMO/61214
フルテキストURL 74_6_537.pdf
著者 Morimoto, Yusuke| Komatsu, Taichi| Tokuhashi, Yasuaki|
抄録 Active treatment with intramedullary screw fixation is now common for athletes with Jones fracture. Outcomes are generally good, but complications can occur. We report 4 rare complications of intramedullary screw fixa-tion. Two cases developed osteomyelitis and pseudarthrosis caused by thermal necrosis. In the other two cases, screw-related complications occurred during the insertion of the tapered headless screw. Although thermal necrosis and screw insertion failures are considered rare complications and not widely reported in the litera-ture, they do occur occasionally. Knowing the mechanisms underlying these complications could help prevent them, and knowing their course could lead caregivers to appropriate interventions when they do occur.
キーワード Jones fracture thermal necrosis tapered headless screw
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2020-12
74巻
6号
出版者 Okayama University Medical School
開始ページ 537
終了ページ 544
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33361875
Web of Science KeyUT 000601203600011
NAID 120006948953
JaLCDOI 10.18926/AMO/61212
フルテキストURL 74_6_525.pdf
著者 Aoki, Hideki| Utsumi, Masashi| Kimura, Yuji| Takahashi, Yosuke| Nagahisa, Seiichi| Nishimura, Seitaro| Une, Yuta| Watanabe, Megumi| Taniguchi, Fumitaka| Arata, Takashi| Katsuda, Koh| Tanakaya, Kohji|
抄録 Cardiac metastasis originating from hepatocellular carcinoma (HCC) is a rare condition with a poor prognosis. No therapeutic standards for cardiac metastasis originating from HCC have been established. At 19 months after a curative hepatectomy, a 64-year-old Japanese hepatitis B virus-positive male patient experienced solitary cardiac metastasis originating from HCC. The cardiac tumor was discovered in the right ventricle. The patient received three courses of radiotherapy and chemotherapy and survived > 3 years after the initial diagnosis of cardiac metastasis. His case demonstrates that radiotherapy combined with chemotherapy can be an effective treatment for cardiac metastasis.
キーワード hepatocellular carcinoma cardiac metastasis radiotherapy chemotherapy
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2020-12
74巻
6号
出版者 Okayama University Medical School
開始ページ 525
終了ページ 530
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33361873
Web of Science KeyUT 000601203600009
NAID 120006948951
JaLCDOI 10.18926/AMO/61211
フルテキストURL 74_6_521.pdf
著者 Itazaki, Yujiro| Tsujimoto, Hironori| Sugasawa, Hidekazu| Yaguchi, Yoshihisa| Nomura, Shinsuke| Ito, Nozomi| Harada, Manabu| Sugihara, Takao| Tsuchiya, Satoshi| Ishibashi, Yusuke| Kouzu, Keita| Kishi, Yoji| Ueno, Hideki |
抄録 We report a successful dissection of metastatic posterior thoracic para-aortic lymph node (No. 112aoP) via bilateral thoracoscopic surgery. With the anesthetized patient (a 73-year-old Japanese woman) in the prone position, two working ports were inserted for the left-side approach, and artificial pneumothorax was created. Thoracoscopic examination revealed a swollen LN posterior to the descending aorta. Fat and metastatic LNs posterior to the aorta were dissected from the aortic arch level to the diaphragm while preserving intercostal arteries. For the right-side approach, two working ports were inserted and a routine thoracoscopic esophagec-tomy was performed. Gastric conduit reconstruction was achieved laparoscopically. Operation time for the left thoracic procedure: 54 min; estimated blood loss: almost none. No recurrence was detected 24 months post-operatively. There are several surgical options for approaching No. 112aoP, including transhiatal, left thora-cotomy, and thoracoscopy. Although a wide dissection of the posterior thoracic para-aortic area has not been reported, it may be feasible and safe if the artery of Adamkiewicz and intercostal arteries are preserved. A min-imally invasive bilateral thoracoscopic approach for a thoracoscopic esophagectomy is safe and useful for esophageal cancer patients with solitary No. 112aoP metastasis.
キーワード bilateral approach posterior thoracic para-aortic lymph node thoracoscopic esophagectomy
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2020-12
74巻
6号
出版者 Okayama University Medical School
開始ページ 521
終了ページ 524
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33361872
Web of Science KeyUT 000601203600008
NAID 120006948950
JaLCDOI 10.18926/AMO/61206
フルテキストURL 74_6_475.pdf
著者 Harada, Ryo| Sato, Ryosuke| Tsutsui, Tomoaki| Hattori, Nao| Inoue, Masafumi| Kobashi, Haruhiko|
抄録 The insertion of a self-expandable metal stent (SEMS) for nonpancreatic cancer is a factor predicting the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP). We evaluated the efficacy of endo-scopic pancreatic stenting (EPS) to prevent PEP after SEMS insertion in patients with malignant distal biliary stricture and without main pancreatic duct (MPD) obstruction. We performed a single-center, retrospective, historically controlled investigation to assess the outcomes of 33 consecutive patients who underwent SEMS insertion. From March 2013 to June 2015, 13 patients did not undergo EPS (Non-EPS group). The other 20 patients underwent EPS (EPS group) between July 2015 and August 2018. The background data demonstrated no significant differences. Except for one patient in the Non-EPS group, all patients underwent biliary sphinc-terotomy. The EPS group’s PEP incidence was significantly lower (n = 1, 5%) than that of the Non-EPS group (n = 4, 31%) (p = 0.04). The median serum amylase and lipase levels after the procedure were significantly lower in the EPS group than in the Non-EPS group (amylase: 104 vs. 262 U/L; p < 0.01, lipase: 102 vs. 666 U/L; p = 0.01). The use of EPS decreased the incidence of PEP after SEMS insertion in individuals with malignant distal biliary stricture and without MPD obstruction.
キーワード post-endoscopic retrograde cholangiopancreatography pancreatitis endoscopic pancreatic stent main pancreatic duct obstruction self-expandable metal stent distal biliary stricture
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2020-12
74巻
6号
出版者 Okayama University Medical School
開始ページ 475
終了ページ 481
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33361867
Web of Science KeyUT 000601203600003
NAID 120006948956
フルテキストURL fulltext.pdf
著者 Ogura, Kiyotake| Yanagida, Noriyuki| Sato, Sakura| Imai, Takanori| Ito, Komei| Kando, Naoyuki| Ikeda, Masanori| Shibata, Rumiko| Murakami, Yoko| Fujisawa, Takao| Nagao, Mizuho| Kawamoto, Norio| Kondo, Naomi| Urisu, Atsuo| Tsuge, Ikuya| Kondo, Yasuto| Sugai, Kazuko| Uchida, Osamu| Urashima, Mitsuyoshi| Taniguchi, Masami| Ebisawa, Motohiro|
キーワード Food hypersensitivity Immunotherapy Dose-response relationship Desensitization
発行日 2020-10
出版物タイトル World Allergy Organization Journal
13巻
10号
出版者 Elsevier
開始ページ 100463
ISSN 1939-4551
NCID AA12582077
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
PubMed ID 33024480
DOI 10.1016/j.waojou.2020.100463
Web of Science KeyUT 000595303200004
関連URL isVersionOf https://doi.org/10.1016/j.waojou.2020.100463
フルテキストURL fulltext.pdf
著者 Uraguchi, Kensuke| Kozakura, Kenichi| Oka, Satoshi| Higaki, Takaya| Makihara, Seiichiro| Imai, Toshi| Doi, Akira| Ohta, Tsuyoshi| Kariya, Shin| Nishizaki, Kazunori|
キーワード Rhinocerebral mucormycosis Acute rhinosinusitis Brain abscess Endoscopic endonasal skull base surgery Acute monocytic leukemia
発行日 2020-12
出版物タイトル Medical Mycology Case Reports
30巻
出版者 Elsevier
開始ページ 22
終了ページ 25
ISSN 2211-7539
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
PubMed ID 33083212
DOI 10.1016/j.mmcr.2020.09.004
Web of Science KeyUT 000600608700007
関連URL isVersionOf https://doi.org/10.1016/j.mmcr.2020.09.004
フルテキストURL fulltext.pdf
著者 Nishizawa, Hitomi| Sato, Yoshihiko| Ishikawa, Masumi| Arakawa, Yuko| Iijima, Mari| Akiyama, Tomoyuki| Takano, Kyoko| Watanabe, Atsushi| Kosho, Tomoki|
キーワード Hypophosphatasia Alkaline phosphatase Genetic disease Asfotase alfa Recombinant gene therapy Motor function
発行日 2020-12
出版物タイトル Molecular Genetics and Metabolism Reports
25巻
出版者 Elsevier
開始ページ 100643
ISSN 2214-4269
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
PubMed ID 32983894
DOI 10.1016/j.ymgmr.2020.100643
Web of Science KeyUT 000600655200010
関連URL isVersionof https://doi.org/10.1016/j.ymgmr.2020.100643
フルテキストURL fulltext.pdf
著者 Watanabe, Toshiyuki| Takabatake, Kiyofumi| Tsujigiwa, Hidetsugu| Watanabe, Satoko| Nakagiri, Ryoko| Nakano, Keisuke| Nagatsuka, Hitoshi| Kimata, Yoshihiro|
キーワード honeycomb β-TCP bone tissue regeneration bone microenvironment Vertical and Horizontal holes geometrical structure
発行日 2020-10-25
出版物タイトル Materials
13巻
21号
出版者 MDPI
開始ページ 4761
ISSN 1996-1944
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by the authors.
論文のバージョン publisher
PubMed ID 33113818
DOI 10.3390/ma13214761
Web of Science KeyUT 000589377800001
関連URL isVersionOf https://doi.org/10.3390/ma13214761
フルテキストURL K0006271_abstract_review.pdf K0006271_summary.pdf
著者 SUMINTO SYAEFUDIN|
発行日 2020-09-25
資料タイプ 学位論文
学位授与番号 甲第6271号
学位授与年月日 2020-09-25
学位・専攻分野 博士(学術)
授与大学 岡山大学
言語 英語
フルテキストURL O0004527_abstract_review.pdf O0004527_summary.pdf.pdf
著者 西原 一幸|
発行日 2020-09-25
資料タイプ 学位論文
学位授与番号 乙第4527号
学位授与年月日 2020-09-25
学位・専攻分野 博士(文学)
授与大学 岡山大学
言語 日本語
フルテキストURL O0004526_abstract_review.pdf O0004526_summary.pdf O0004256_fulltext.pdf
著者 上山 和子|
発行日 2020-09-25
資料タイプ 学位論文
学位授与番号 乙第4526号
学位授与年月日 2020-09-25
学位・専攻分野 博士(看護学)
授与大学 岡山大学
言語 日本語