検索結果 - 岡山大学学術成果リポジトリ

Testosterone Recovery after Neoadjuvant Gonadotropin-Releasing Hormone Antagonist versus Agonist on Permanent Iodine-125 Seed Brachytherapy in Prostate Cancer Patients: A Propensity Score Analysis

JaLCDOI	10.18926/AMO/62810
フルテキストURL	75_6_705.pdf
著者	Iwata, Takehiro\| Maruyama, Yuki\| Kawada, Tatsushi\| Sadahira, Takuya\| Katayama, Satoshi\| Takamoto, Atsushi\| Sako, Tomoko\| Wada, Koichiro\| Edamura, Kohei\| Kobayashi, Yasuyuki\| Araki, Motoo\| Watanabe, Masami\| Watanabe, Toyohiko\| Nasu, Yasutomo\|
抄録	Optimal neoadjuvant hormone therapy (NHT) for reducing prostate cancer (PC) patients’ prostate volume pre-brachytherapy is controversial. We evaluated the differential impact of neoadjuvant gonadotropin-releasing hormone (GnRH) antagonist versus agonist on post-brachytherapy testosterone recovery in 112 patients treated pre-brachytherapy with NHT (GnRH antagonist, n=32; GnRH agonists, n=80) (Jan. 2007-June 2019). We assessed the effects of patient characteristics and a GnRH analogue on testosterone recovery with logistic regression and a propensity score analysis (PSA). There was no significant difference in the rate of testosterone recovery to normal levels (> 300 ng/dL) between the GnRH antagonist and agonists (p=0.07). The GnRH agonists induced a significantly more rapid testosterone recovery rate at 3 months post-brachytherapy versus the GnRH antagonist (p<0.0001); there was no difference in testosterone recovery at 12 months between the GnRH antagonist/agonists (p=0.8). In the multivariate analysis, no actor was associated with testosterone recovery. In the PSA, older age and higher body mass index (BMI) were significantly associated with longer testosterone recovery. Post-brachytherapy testosterone recovery was quicker with the neoadjuvant GnRH agonists than the antagonist, and the testosterone recovery rate was significantly associated with older age and higher BMI. Long-term follow-ups are needed to determine any differential effects of GnRH analogues on the quality of life of brachytherapy-treated PC patients.
キーワード	testosterone recovery GnRH antagonist GnRH agonist brachytherapy prostate cancer
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	705
終了ページ	711
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955538
Web of Science KeyUT	000735297900006
NAID	120007180282

Evaluation of Preoperative Magnetic Resonance Cholangiopancreatography in Acute Cholecystitis to Predict Technical Difficulties in Laparoscopic Cholecystectomy

JaLCDOI	10.18926/AMO/62807
フルテキストURL	75_6_685.pdf
著者	Yamashita, Mampei\| Kuroki, Tamotsu\| Hamada, Takashi\| Hirayama, Takanori\| Tokunaga, Takayuki\| Yamanouchi, Kosho\| Takeshita, Hiroaki\| Maeda, Shigeto\|
抄録	Magnetic resonance cholangiopancreatography (MRCP) is a non-invasive imaging technique that provides high-quality visualization of the biliary tree, including the gallbladder. This study aimed to evaluate the useful-ness of preoperative MRCP for acute cholecystitis in predicting technical difficulties during laparoscopic chole-cystectomy (LC). A total of 168 patients who underwent LC with preoperative MRCP were enrolled in this study. Patients were divided into two groups according to preoperative MRCP findings: the visualized group (n = 126), in which the entire gallbladder could be visualized; and the non-visualized group (n = 42), in which the entire gallbladder could not be visualized. The perioperative characteristics and postoperative complica-tions of the two groups were retrospectively analyzed. Operation time was longer in the non-visualized group (median 101.5 vs. 143.5 min; p < 0.001). The non-visualized group had significantly more intraoperative blood loss than the visualized group (median 5 vs. 10 g; p = 0.05). The rate of conversion to open cholecystectomy was significantly higher in the non-visualized group (1.6 vs. 9.5%; p = 0.03). In conclusion, patients in the non- visualized group showed higher difficulty in performance of LC. Our MRCP-based classification is a simple and effective means of predicting difficulties in performing LC for acute cholecystitis.
キーワード	laparoscopic cholecystectomy magnetic resonance cholangiopancreatography acute cholecystitis gallbladder disease non-invasive imaging
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	685
終了ページ	689
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955535
Web of Science KeyUT	000735297900003
NAID	120007180285

Multiple Roles of Histidine-Rich Glycoprotein in Vascular Homeostasis and Angiogenesis

JaLCDOI	10.18926/AMO/62805
フルテキストURL	75_6_671.pdf
著者	Gao, Shangze\| Nishibori, Masahiro\|
抄録	Histidine-rich glycoprotein (HRG) is a 75 kDa plasma protein that is synthesized in the liver of many verte-brates and present in their plasma at relatively high concentrations of 100-150 μg/mL. HRG is an abundant and well-characterized protein having a multidomain structure that enable it to interact with many ligands, func-tion as an adaptor molecule, and participate in numerous physiological and pathological processes. As a plasma protein, HRG has been reported to regulate vascular biology, including coagulation, fibrinolysis and angiogenesis, through its binding with several ligands (heparin, FXII, fibrinogen, thrombospondin, and plas-minogen) and interaction with many types of cells (endothelial cells, erythrocytes, neutrophils and platelets). This review aims to summarize the roles of HRG in maintaining vascular homeostasis and regulating angiogen-esis in various pathological conditions.
キーワード	histidine-rich glycoprotein vascular biology coagulation angiogenesis
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	671
終了ページ	675
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955533
Web of Science KeyUT	000735297900001
NAID	120007180287

Transtubular Endoscopic Posterolateral Decompression of the L5 Root under Navigation and O-arm: A Technical Note

JaLCDOI	10.18926/AMO/62777
フルテキストURL	75_5_637.pdf
著者	Mehta, Rahul\| Tanaka, Masato\| Oda, Yoshiaki\| Fujiwara, Yoshihiro\| Uotani, Koji\| Arataki, Shinya\| Yamauchi, Taro\|
抄録	Among studies evaluating minimally invasive surgical (MIS) decompression of the L5 root, techniques involving transtubular endoscopic decompression under O-arm navigation are rare. We present the case of a 68-yearold woman with left leg pain, muscle weakness and gait disturbance of one month duration. The patient underwent transtubular endoscopic decompression under O-arm navigation. There is no radiation hazard to the operating room staff with this procedure. After surgery, the patient had significant pain relief and her left lower limb motor function had improved by follow-up at one year. C-arm-free endoscopic L5 root decompression is a safe and effective procedure.
キーワード	C-arm-free, navigation O-arm navigation endoscopic surgery L5 root decompression
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-10
巻	75巻
号	5号
出版者	Okayama University Medical School
開始ページ	637
終了ページ	640
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34703047
Web of Science KeyUT	Transtubular Endoscopic Posterolateral Decompression of the L5 Root under Navigation and O-arm: A Technical Note 000711568400002
NAID	120007166677

Factors for Acute Kidney Injury Following Total Arch Replacement and Association with Temperature Management During Cardiopulmonary Bypass: A Single-center Retrospective Observational Study

JaLCDOI	10.18926/AMO/62771
フルテキストURL	75_5_585.pdf
著者	Omiya, Hiroki\| Takatori, Makoto\| Yunoki, Keiji\| Morimatsu, Hiroshi\|
抄録	Many patients develop acute kidney injury (AKI) after vascular surgery. In this retrospective observational study, we investigated the risk factors for AKI defined using the Kidney Disease Improving Global Outcomes criteria after total arch replacement (TAR). Additionally, we investigated the influence of temperature manage-ment during cardiopulmonary bypass (CPB) on postoperative renal function by propensity score-matched anal-ysis. We retrospectively analyzed 161 consecutive patients who underwent TAR between 2016 and 2019. Postoperative AKI occurred in 48.7% of the patients. In the multivariate analysis, male sex (odds ratio [OR] 3.95, 95% confidence interval [95%CI] 1.56-8.27, p = 0.002), ACE inhibitors/ARB medication (OR 3.19, 95%CI 1.49-6.82, p = 0.003), preoperative chronic kidney disease (OR 2.47, 95%CI 1.17-5.23, p = 0.02), pro-longed CPB time (OR 2.36, 95%CI 1.05-5.34, p = 0.04), and lower body ischemic time during CPB (OR 2.20, 95%CI 1.05-4.46, p = 0.04) were identified as independent risk factors for AKI. Propensity score-matched anal-ysis showed no significant difference in the risk of AKI following TAR between mild hypothermia or normo-thermia and moderate hypothermia (37.2% vs. 41.9%, p = 0.83). In conclusion, modifiable risk factors for AKI included prolonged CPB time and lower body ischemic time. Temperature management during CPB had no clear effect on outcomes.
キーワード	acute kidney injury total arch replacement cardiopulmonary bypass lower body ischemic time
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-10
巻	75巻
号	5号
出版者	Okayama University Medical School
開始ページ	585
終了ページ	593
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34703041
Web of Science KeyUT	000711561600005
NAID	120007166671

Relationship between Pressure Ulcers in Elderly People and Physiological Indices of the Skin

JaLCDOI	10.18926/AMO/62768
フルテキストURL	75_5_557.pdf
著者	Takeshima Kohara, Hiroko\| Ikeda, Mitsunori \| Okawa, Masami\|
抄録	This study examined the relationship between skin physiological indices and pressure ulcers in elderly people. The subjects were 55 bedridden elderly Japanese patients with a median age of 85 years. The following parame-ters were measured using non-invasive devices: skin surface temperature, moisture content in the stratum corneum, moisture content in the dermis, transepidermal water loss as an index of skin barrier function, skin erythema and skin elasticity. The sacral and 2 heel areas were observed as sites predisposed to pressure ulcers. Within one month after measuring the skin physiological indices, we confirmed pressure ulcers of National Pressure Ulcer Advisory Panel classification Stage II or worse based on medical records. Among the 55 patients, 4 (7.3%) prospectively developed a total of 5 pressure ulcers within 16 days. Only the skin erythema score was significantly higher with than without pressure ulcers (p < 0.001). We performed a binary logistic regression analysis and confirmed a significant relationship between pressure-ulcer development and the level of erythema (odds ratio = 1.026; 95% confidence interval: 1.011-1.042). Skin erythema increased before the development of pressure ulcers. Taken together, our results show that the high skin erythema score can be a predictive indicator of pressure ulcers.
キーワード	elderly people erythema pressure ulcer skin
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-10
巻	75巻
号	5号
出版者	Okayama University Medical School
開始ページ	557
終了ページ	565
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34703038
Web of Science KeyUT	000711561600002
NAID	120007166668

Glial Cells as Possible Targets of Neuroprotection through Neurotrophic and Antioxidative Molecules in the Central and Enteric Nervous Systems in Parkinson’s Disease

JaLCDOI	10.18926/AMO/62767
フルテキストURL	75_5_549.pdf
著者	Isooka, Nami\| Miyazaki, Ikuko\| Asanuma, Masato\|
抄録	Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide. The loss of nigrostriatal dopaminergic neurons produces its characteristic motor symptoms, but PD patients also have non-motor symptoms such as constipation and orthostatic hypotension. The pathological hallmark of PD is the presence of α-synuclein-containing Lewy bodies and neurites in the brain. However, the PD pathology is observed in not only the central nervous system (CNS) but also in parts of the peripheral nervous system such as the enteric nervous system (ENS). Since constipation is a typical prodromal non-motor symptom in PD, often preceding motor symptoms by 10-20 years, it has been hypothesized that PD pathology propagates from the ENS to the CNS via the vagal nerve. Discovery of pharmacological and other methods to halt this progression of neurodegeneration in PD has the potential to improve millions of lives. Astrocytes protect neurons in the CNS by secretion of neurotrophic and antioxidative factors. Similarly, astrocyte-like enteric glial cells (EGCs) are known to secrete neuroprotective factors in the ENS. In this article, we summarize the neuroprotective function of astrocytes and EGCs and discuss therapeutic strategies for the prevention of neurodegeneration in PD targeting neurotrophic and antioxidative molecules in glial cells.
キーワード	Parkinson’s disease astrocyte enteric glial cell neurotrophic factor antioxidative molecule
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2021-10
巻	75巻
号	5号
出版者	Okayama University Medical School
開始ページ	549
終了ページ	556
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34703037
Web of Science KeyUT	000711561600001
NAID	120007166678

Gender-Dependent Characteristics of Serum 1,25-Dihydroxyvitamin D/25-Hydroxyvitamin D Ratio for the Assessment of Bone Metabolism

フルテキストURL	fulltext.pdf
著者	Fujita-Yamashita, Manami\| Yamamoto, Koichiro\| Honda, Hiroyuki\| Hanayama, Yoshihisa\| Tokumasu, Kazuki\| Nakano, Yasuhiro\| Hasegawa, Kou\| Hagiya, Hideharu\| Obika, Mikako\| Ogawa, Hiroko\| Otsuka, Fumio\|
キーワード	aging bone metabolism calcium cyp27b1 vitamin d
発行日	2021-09-18
出版物タイトル	Cureus
巻	13巻
号	9号
出版者	Cureus Inc
開始ページ	e18070
ISSN	2168-8184
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 Fujita-Yamashita et al.
論文のバージョン	publisher
DOI	10.7759/cureus.18070
Web of Science KeyUT	000701650300002
関連URL	isVersionOf https://doi.org/10.7759/cureus.18070

Virulence of Cholera Toxin Gene-Positive Vibrio cholerae Non-O1/non-O139 Strains Isolated From Environmental Water in Kolkata, India

フルテキストURL	fulltext.pdf
著者	Takahashi, Eizo\| Ochi, Sadayuki\| Mizuno, Tamaki\| Morita, Daichi\| Morita, Masatomo\| Ohnishi, Makoto\| Koley, Hemanta\| Dutta, Moumita\| Chowdhury, Goutam\| Mukhopadhyay, Asish K.\| Dutta, Shanta\| Miyoshi, Shin-Ichi\| Okamoto, Keinosuke\|
キーワード	Vibrio cholerae NAG Vibrio cholera toxin virulence environmental water gene analysis
発行日	2021-08-20
出版物タイトル	Frontiers In Microbiology
巻	12巻
出版者	Frontiers Media SA
開始ページ	726273
ISSN	1664-302X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 Takahashi, Ochi, Mizuno, Morita, Morita, Ohnishi, Koley, Dutta, Chowdhury, Mukhopadhyay, Dutta, Miyoshi and Okamoto.
論文のバージョン	publisher
PubMed ID	34489915
DOI	10.3389/fmicb.2021.726273
Web of Science KeyUT	000696600200001
関連URL	isVersionOf https://doi.org/10.3389/fmicb.2021.726273

Immunoelectron Microscopic Characterization of Vasopressin-Producing Neurons in the Hypothalamo-Pituitary Axis of Non-Human Primates by Use of Formaldehyde-Fixed Tissues Stored at-25 degrees C for Several Years

フルテキストURL	fulltext.pdf
著者	Otubo, Akito\| Maejima, Sho\| Oti, Takumi\| Satoh, Keita\| Ueda, Yasumasa\| Morris, John F.\| Sakamoto, Tatsuya\| Sakamoto, Hirotaka\|
キーワード	vasopressin corticotrophin-releasing factor glutamate paraventricular nucleus of the hypothalamus Japanese macaque monkey post-embedding immunoelectron microscopy dense-cored neurosecretory vesicle
発行日	2021-08-25
出版物タイトル	International Journal of Molecular Sciences
巻	22巻
号	17号
出版者	MDPI
開始ページ	9180
ISSN	1422-0067
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 by the authors.
論文のバージョン	publisher
PubMed ID	34502087
DOI	10.3390/ijms22179180
Web of Science KeyUT	000694296600001
関連URL	isVersionOf https://doi.org/10.3390/ijms22179180

Effect of Angiotensin II on Chondrocyte Degeneration and Protection via Differential Usage of Angiotensin II Receptors

フルテキストURL	fulltext.pdf
著者	Nishida, Takashi\| Akashi, Sho\| Takigawa, Masaharu\| Kubota, Satoshi\|
キーワード	angiotensin II cellular communication network factor 2 (CCN2) renin-angiotensin system (RAS) losartan angiotensin II type I receptor (AT(1)R)
発行日	2021-08-25
出版物タイトル	International Journal of Molecular Sciences
巻	22巻
号	17号
出版者	MDPI
開始ページ	9204
ISSN	1422-0067
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 by the authors.
論文のバージョン	publisher
PubMed ID	34502113
DOI	10.3390/ijms22179204
Web of Science KeyUT	000694359000001
関連URL	isVersionOf https://doi.org/10.3390/ijms22179204

Comparison of Oxygen Saturation Between Nasal High-Flow Oxygen and Conventional Nasal Cannula in Obese Patients Undergoing Dental Procedures With Deep Sedation: A Randomized Crossover Trial

フルテキストURL	fulltext20210914-1.pdf figures20210914-1.pdf
著者	Higuchi, Hitoshi\| Takaya-Ishida, Kumiko\| Miyake, Saki\| Fujimoto, Maki\| Nishioka, Yukiko\| Maeda, Shigeru\| Miyawaki, Takuya\|
備考	This is an Accepted Manuscript of an article published by Elsevier. © 2021 The American Association of Oral and Maxillofacial Surgeon. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.joms.2021.04.004] .\|
発行日	2021-9
出版物タイトル	Journal of Oral and Maxillofacial Surgery
巻	79巻
号	9号
出版者	Elsevier BV
開始ページ	1842
終了ページ	1850
ISSN	0278-2391
NCID	AA10628202
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The American Association of Oral and Maxillofacial Surgeon
論文のバージョン	author
PubMed ID	34022138
DOI	10.1016/j.joms.2021.04.004
Web of Science KeyUT	000691194500011
関連URL	https://doi.org/10.1016/j.joms.2021.04.004

Study protocol for endoscopic ultrasonography-guided ethanol injection therapy for patients with pancreatic neuroendocrine neoplasm: a multicentre prospective study

フルテキストURL	fulltext.pdf
著者	Matsumoto, Kazuyuki\| Kato, Hironari\| Kitano, Masayuki\| Hara, Kazuo\| Kuwatani, Masaki\| Ashida, Reiko\| Takenaka, Mamoru\| Yamazaki, Tatsuhiro\| Sakurai, Jun\| Yoshida, Michihiro\| Okada, Hiroyuki\|
キーワード	gastroenterology endoscopy pancreatic disease
発行日	2021
出版物タイトル	BMJ Open
巻	11巻
号	7号
出版者	BMJ Publishing Group
開始ページ	e046505
ISSN	2044-6055
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Author(s) (or their employer(s)) 2021.
論文のバージョン	publisher
PubMed ID	34253667
DOI	10.1136/bmjopen-2020-046505
Web of Science KeyUT	000691612700018
関連URL	isVersionOf https://doi.org/10.1136/bmjopen-2020-046505

Usefulness of Middle Colic Artery Transposition Technique for Hepatic Arterial Reconstruction in Conversion Surgery for an Initially Unresectable, Locally Advanced Pancreatic Cancer

JaLCDOI	10.18926/AMO/62410
フルテキストURL	75_4_543.pdf
著者	Yoshida, Ryuichi\| Yagi, Takahito\| Yasui, Kazuya\| Umeda, Yuzo\| Yoshida, Kazuhiro\| Fuji, Tomokazu\| Takagi, Kosei\| Kumano, Kenjiro\| Yoshimoto, Masashi\| Fujiwara, Toshiyoshi\|
抄録	The outcomes of pancreatectomy with resection and reconstruction of the involved arteries for locally advanced pancreatic cancer following chemotherapy have improved in recent years. In pancreatic head cancers in which there is contact with the common and proper hepatic arteries, margin-negative resection requires pancreati-coduodenectomy, with the resection of these arteries and the restoration of hepatic arterial flow. Here, we describe a middle colic artery transposition technique in hepatic arterial reconstruction during pancreatoduo-denectomy for an initially unresectable locally advanced pancreatic cancer. This technique was effective and may provide a new option for hepatic artery reconstruction in such cases.
キーワード	hepatic artery locally advanced pancreatic cancer middle colic artery pancreatoduodenectomy reconstruction technique
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-08
巻	75巻
号	4号
出版者	Okayama University Medical School
開始ページ	543
終了ページ	548
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34511625
Web of Science KeyUT	000696755800004
NAID	120007146036

An Elderly Male with Primary Sjögren’s Syndrome Presenting Pleuritis as the Initial Manifestation

JaLCDOI	10.18926/AMO/62409
フルテキストURL	75_4_539.pdf
著者	Yamamoto, Yukichika\| Otsuka, Yuki\| Katsuyama, Takayuki\| Nishimura, Yoshito\| Oka, Kosuke\| Hasegawa, Kou\| Hagiya, Hideharu\| Otsuka, Fumio\|
抄録	Primary Sjögren’s syndrome (SS) is an autoimmune disease that usually affects the exocrine glands in mid-dle-aged women. Fifteen percent of SS patients experience severe systemic extraglandular complications, and pleuritis is one of the rare complications of SS. We report the case of an elderly Japanese man who initially pre-sented with a prolonged fever and chest pain and was finally diagnosed with primary SS-associated pleuritis. Of the nine reported cases of primary SS that initially presented with pleuritis, up to six cases were elderly males. This case highlights the complication of pleuritis among elderly males with primary SS.
キーワード	Sjögren’s syndrome pleuritis elderly male
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-08
巻	75巻
号	4号
出版者	Okayama University Medical School
開始ページ	539
終了ページ	542
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34511624
Web of Science KeyUT	000696755800003
NAID	120007146035

Laparoscopic Synchronous Resection for Descending Colon Cancer and Tailgut Cyst

JaLCDOI	10.18926/AMO/62407
フルテキストURL	75_4_529.pdf
著者	Inada, Ryo\| Watanabe, Ayako\| Toshima, Toshiaki\| Katsura, Yuki\| Sato, Takuji\| Sui, Kenta\| Oishi, Kazuyuki\| Okabayashi, Takehiro\| Ozaki, Kazuhide\| Shibuya, Yuichi\| Matsumoto, Manabu\| Iwata, Jun\|
抄録	A 67-year-old woman underwent polypectomy for a tumor at the descending colon. Pathologically, the tumor was diagnosed as adenocarcinoma with an invasion of 2000 μm. Computed tomography showed a swollen paracolic lymph node and a mass lesion in the presacral space. Magnetic resonance imaging revealed a multio-cular cystic lesion. On diagnosis of descending colon cancer and tailgut cyst, she underwent synchronous lapa-roscopic resection. Histopathologically, the colon cancer was diagnosed as pT1bN1M0, pStage IIIa. The pre-sacral cystic lesion was diagnosed as a nonmalignant tailgut cyst with negative surgical margin. The patient is currently doing well without recurrence at 28 months.
キーワード	anterior approach laparoscopic resection tailgut cyst
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-08
巻	75巻
号	4号
出版者	Okayama University Medical School
開始ページ	529
終了ページ	532
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34511622
Web of Science KeyUT	000696755800001
NAID	120007146033

Synchronous Total Occlusion of the Celiac Axis and Superior Mesenteric Artery: An Autopsy Case

JaLCDOI	10.18926/AMO/62406
フルテキストURL	75_4_523.pdf
著者	Yamashita, Mampei\| Kuroki, Tamotsu\| Matsuoka, Yuki\| Miura, Shiro\| Hamada, Takashi\| Hirayama, Takanori\| Yoneda, Akira\| Tokunaga, Takayuki\| Yamanouchi, Kosho\| Takeshita, Hiroaki\| Maeda, Shigeto\|
抄録	Acute mesenteric ischemia (AMI) is often caused by superior mesenteric artery (SMA) embolization. We report a rare case of synchronous celiac axis and SMA embolization in an elderly woman with initially mild abdominal pain. Ultimately, a second contrast-enhanced computed tomography revealed extensive necrosis from the stomach to the transverse colon together with liver ischemia due to hours of occlusion. Multiorgan failure made palliation the only option, and she died the following evening. Autopsy revealed a fragile atherosclerosis-asso-ciated thrombus. Careful examination and repeat diagnostic tests should be performed in patients with mild abdominal symptoms at risk for AMI.
キーワード	atherosclerosis celiac axis mesenteric ischemia superior mesenteric artery thromboembolism
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-08
巻	75巻
号	4号
出版者	Okayama University Medical School
開始ページ	523
終了ページ	527
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34511621
Web of Science KeyUT	000709282300007
NAID	120007146032

Association Between Eosinophilia and Late-onset Circulatory Collapse in Preterm Infants: A case-Control Study

JaLCDOI	10.18926/AMO/62403
フルテキストURL	75_4_505.pdf
著者	Okamura, Tomoka\| Washio, Yosuke\| Watanabe, Hirokazu\| Nakanishi, Hidehiko\| Uchiyama, Atsushi\| Tsukahara, Hirokazu\| Kusuda, Satoshi\|
抄録	Late-onset circulatory collapse (LCC) in preterm infants is presumably caused by relative adrenal insufficiency. Because eosinophilia is known to be associated with adrenal insufficiency, we attempted to clarify the relation-ship between eosinophilia and LCC in preterm infants. We divided the cases of the infants (born at < 28 weeks’ gestation) admitted to our neonatal intensive care unit in 2008-2010 into 2 groups: those diagnosed with LCC that received glucocorticoids (LCC group), and those who did not receive glucocorticoids (control group). We compared eosinophil counts between the 2 groups and between before and after glucocorticoid treatment in the LCC group. A total of 28 infants were examined: LCC group (n = 12); control group (n = 16). The peak eosin-ophil counts of the LCC group were significantly higher than those of the control group (median: 1.392 × 109/L vs. 1.033 × 109/L, respectively; p = 0.02). Additionally, in the LCC group, the eosinophil counts declined significantly after glucocorticoid treatment (0.877 × 109/L vs. 0.271 × 109/L, p = 0.003). Eosinophil counts in the LCC group were significantly higher than in the control group and decreased rapidly after gluco-corticoid treatment. These results indicate that eosinophilia may be a factor associated with LCC caused by adrenal insufficiency.
キーワード	late-onset circulatory collapse preterm infant eosinophilia steroid adrenal insufficiency
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-08
巻	75巻
号	4号
出版者	Okayama University Medical School
開始ページ	505
終了ページ	509
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34511618
Web of Science KeyUT	000709282300004
NAID	120007146046

Long-term Multidisciplinary Rehabilitation Efficacy in Older Patients After Traumatic Brain Injury: Assessed by the Functional Independence Measure

JaLCDOI	10.18926/AMO/62400
フルテキストURL	75_4_479.pdf
著者	Harada, Akio\| Kawai, Nobuyuki\| Ogawa, Tomoya\| Hatakeyama, Tetsuhiro\| Tamiya, Takashi\|
抄録	Instances of traumatic brain injury (TBI) in the elderly have been increasing along with the aging of popula-tions. In the present study, we examined the effect of aging on long-term multidisciplinary in-patient rehabili-tation efficacy after TBI. Sixty-three patients with physical and cognitive impairments after TBI were enrolled in this study. Patients were divided into 4 age groups (≤ 24, 25-44, 45-64, ≥ 65 years) and the clinical charac-teristics and rehabilitation efficacy of each age group were determined. Functional disability was evaluated using motor and cognitive Functional Independence Measure (FIM) scores. Rehabilitation efficacy was assessed by FIM gains during rehabilitation and compared among the groups. There were no statistically significant dif-ferences in motor and cognitive FIM gains among the age groups. However, cognitive FIM gain was limited in a subset of ≥ 65 patients, and initial cognitive measures could not predict cognitive FIM improvement. These results indicate that chronological age is insufficient to accurately predict rehabilitation efficacy in older TBI patients, and that such patients should be considered candidates for intensive rehabilitation programs based on these results. Accurate prognostication of rehabilitation efficacy with continuing data collection is important when using rehabilitation resources for older TBI patients.
キーワード	aging Functional Independence Measure physical and cognitive impairments traumatic brain injury rehabilitation
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-08
巻	75巻
号	4号
出版者	Okayama University Medical School
開始ページ	479
終了ページ	486
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34511615
Web of Science KeyUT	000709282300001
NAID	120007146043

Differences in Attitudes and Practices of Cancer Pain Management between Medical Oncologists and Palliative Care Physicians

JaLCDOI	10.18926/AMO/62394
フルテキストURL	75_4_431.pdf
著者	Kunitomi, Toshiki\| Nasu, Junichirou\| Minami, Daisuke\| Iwamoto, Takayuki\| Nishie, Hiroyuki\| Saito, Shinya\| Fujiwara, Toshiyoshi\| Matsuoka, Junji\|
抄録	This study aimed to evaluate whether there are differences in the attitudes and practices of cancer pain manage-ment between medical oncologists and palliative care physicians. An online nationwide survey was used to collect responses from board-certified medical oncologists and palliative care physicians in Japan. The survey questionnaire comprised 30 questions. The differences in responses between medical oncologists and palliative care physicians were examined. Out of the 1,227 questionnaires sent, 522 (42.5%) were returned. After apply-ing the exclusion criteria, 445 questionnaires (medical oncologists: n = 283; palliative care physicians: n = 162) were retained for analysis. Among the questions about potential barriers to optimal cancer pain man-agement, both medical oncologists and palliative care physicians considered the reluctance of patients to take opioids due to fear of adverse effects as the greatest barrier. Significantly different ratings between medical oncologists and palliative care physicians were observed on 5 of the 8 questions in this area. Significantly differ-ent ratings were observed for all questions concerning pain specialists and their knowledge. For effective cancer pain management, it is important to account for differences in attitudes and practice between medical oncolo-gists and palliative care physicians.
キーワード	cancer pain management opioid medical oncologist palliative care physician barriers
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-08
巻	75巻
号	4号
出版者	Okayama University Medical School
開始ページ	431
終了ページ	437
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34511609
Web of Science KeyUT	000697944600004
NAID	120007146037