検索結果 1274 件
| JaLCDOI | 10.18926/AMO/68651 |
|---|---|
| フルテキストURL | 79_2_123.pdf |
| 著者 | Akatsuka, Riku| Kimura, Shuhei| Matoba, Ryo| Morizane Hosokawa, Mio| Shiode, Yusuke| Morita, Tetsuro| Doi, Shinichiro| Morizane, Yuki| |
| 抄録 | A 78-year-old woman presented with sudden vision loss and central scotoma. Visual acuity in the right eye was 20/222, with submacular hemorrhage (SMH) and Henle fiber layer hemorrhage (HFLh) due to retinal arterial macroaneurysm (RAM) rupture. She underwent SMH displacement, including cataract surgery, vitrectomy, intravitreal injection of tissue-plasminogen activator, and air tamponade. Three months postoperatively the SMH and HFLh had disappeared and visual acuity had improved to 20/200. Six months postoperatively, a macular hole had developed. We performed an inverted internal limiting membrane flap and gas tamponade. Ten months later, the hole had closed and visual acuity had improved to 20/100. |
| キーワード | submacular hemorrhage Henle fiber layer hemorrhage retinal arterial macroaneurysm rupture macular hole inverted internal limiting membrane flap technique |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-04 |
| 巻 | 79巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 123 |
| 終了ページ | 127 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| JaLCDOI | 10.18926/AMO/68648 |
|---|---|
| フルテキストURL | 79_2_101.pdf |
| 著者 | Isozaki, Hiroshi| Matsumoto, Sasau| Takama, Takehiro| Isozaki, Yuka| |
| 抄録 | To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surgery (2005-2022) at our hospital. In this cohort, 53% (278/521) of the patients who underwent breast conservative surgery (BCS) and 96% (124/129) of those treated with mastectomy did not receive POI. The patients who underwent BCS were treated with POI using opposing tangential field irradiation. A false negative (FN) SLN was retrospectively defined as a negative metastasis in SLN plus positive recurrence in the axillary lymph nodes. Recurrence was detected in 83 patients. A logistic regression analysis revealed that the nuclear grade (odds ratio [OR] 1.69), POI (OR 0.41), and postoperative hormone therapy (OR 0.40) were each significantly related to recurrence. The 26.1% (12/46) FN rate of the non-POI patients decreased to 5.8% (1/17) compared to those treated with POI. The rate of axillary recurrence was significantly lower in the POI group (0.4%) versus the non-POI group (2.7%) (p=0.0355). The rate of locoregional recurrence was also significantly lower in the POI group (2.0%) versus the non-POI group (13.4%) (p<0.0001). No significant difference was observed in the rate of distant recurrence between the POI (4.0%) and non-POI (3.3%) (p=0.831) groups. These results indicated that the postoperative opposing tangential field irradiation of conserved breast tissue inhibited recurrence in the axillary lymph nodes. |
| キーワード | breast cancer postoperative irradiation radiation therapy sentinel lymph nodes recurrence |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-04 |
| 巻 | 79巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 101 |
| 終了ページ | 107 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| JaLCDOI | 10.18926/AMO/68647 |
|---|---|
| フルテキストURL | 79_2_093.pdf |
| 著者 | Tsuchie, Rina| Fukuda, Mari| Tsumura, Hideki| Kinuta, Minako| Hisamatsu, Takashi| Kanda, Hideyuki| |
| 抄録 | School teachers are subject to both physical and mental health problems. We examined cross-sectional relationships between work engagement and major health outcomes among junior and senior high school teachers in Japan via a nationwide survey in 2019-2020. A total of 3,160 respondents were included in the analyses (19.9% response rate). Work engagement was assessed with the Utrecht Work Engagement Scale-9 (UWES-9), and we thus divided the teachers into quartiles according to their UWES-9 scores. Based on validated questionnaires, we assessed insomnia, psychological distress, and neck pain as health outcomes. A binomial logistic regression adjusted for age, gender, school type, teacher’s roles, involvement in club activities, division of duties, employment status, and whether they lived with family demonstrated that the teachers with lower UWES-9 scores had higher burdens of insomnia, psychological distress, and neck pain (odds ratios [95% confidence intervals] in 4th vs. 1st quartile, 2.92 (2.34-3.65), 3.70 (2.81-4.88), and 2.12 (1.68-2.68), respectively; all trend p<0.001). There were no significant differences in these associations between full-time and part-time teachers. Our findings indicate that low work engagement may contribute to physical and mental health issues among junior and senior high school teachers, thus providing insights for preventing health problems in this profession. |
| キーワード | work engagement school teachers insomnia psychological distress neck pain |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-04 |
| 巻 | 79巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 93 |
| 終了ページ | 100 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| JaLCDOI | 10.18926/AMO/68646 |
|---|---|
| フルテキストURL | 79_2_081.pdf |
| 著者 | Kawada, Tatsushi| Kobayashi, Yasuyuki| Tsugawa, Takuji| Tsuboi, Kazuma| Katayama, Satoshi| Iwata, Takehiro| Bekku, Kensuke| Kobayashi, Tomoko| Edamura, Kohei| Ebara, Shin| Araki, Motoo| |
| 抄録 | We retrospectively evaluated the oncologic outcomes of paclitaxel, cisplatin, and gemcitabine (PCG) with those of gemcitabine and cisplatin (GC) as neoadjuvant chemotherapy in muscle-invasive bladder cancer (MIBC) patients. The primary outcome was efficacy: pathological complete response (pCR), ypT0N0; and pathological objective response (pOR), ypT0N0, ≤ ypT1N0, or ypT0N1. Secondary outcomes included overall survival (OS), recurrence-free survival (RFS), predictive factors for pOR, OS, and RFS, and hematologic adverse events (AEs). Among 113 patients treated (PCG, n=28; GC, n=85), similar pOR and pCR rates were achieved by the groups (pOR: PCG, 57.1% vs. GC, 49. 4%; p=0.52; pCR: PCG, 39.3% vs. GC, 29.4%; p=0.36). No significant differences were observed in OS (p=1.0) or RFS (p=0.20). Multivariate logistic regression analysis showed that hydronephrosis (odds ratio [OR] 0.32, 95%CI: 0.11-0.92) and clinical node-positive status (cN+) (OR 0.22, 95%CI: 0.050-0.99) were significantly associated with a decreased probability of pOR. On multivariate Cox regression analyses, pOR achievement was associated with improved OS (hazard ratio [HR] 0.23, 95%CI: 0.10-0.56) and RFS (HR 0.30, 95%CI: 0.13-0.67). There were no significant between-group differences in the incidence of grade ≥ 3 hematologic AEs or dose-reduction required, but the PCG group had a higher incidence of grade 4 neutropenia. |
| キーワード | urothelial carcinoma paclitaxel cisplatin gemcitabine neoadjuvant |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-04 |
| 巻 | 79巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 81 |
| 終了ページ | 92 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| JaLCDOI | 10.18926/AMO/68645 |
|---|---|
| フルテキストURL | 79_2_075.pdf |
| 著者 | Higaki, Fumiyo| Morimitsu, Yusuke| Iguchi, Toshihiro| Hwang, Sung Il| Kitayama, Takahiro| Takahashi, Yuka| Uka, Mayu| Akagi, Noriaki| Sugaya, Akiko| Mitsuhashi, Toshiharu| Matsui, Yusuke| Hiraki, Takao| |
| 抄録 | Temporal bone computed tomography (CT) is frequently performed for pediatric patients with ear diseases. Advances in CT technology have improved diagnostic imaging quality, but reduction of radiation exposure remains a goal. We evaluated the potential for radiation dose reduction in temporal bone CT examinations using porcine ear ossicles and a photon-counting detector CT system. Three scans of the bilateral temporal bone were performed on each of three pig cadaver heads. In each of seven successive imaging sessions, the radiation dose was reduced by an additional one-seventh of the recommended dose (RD). Two board-certified radiologists independently scored the resulting images on a scale of 1 to 5 points, where 5 represented the image quality at the RD. Images scoring ≥4.5 points were considered acceptable. Noise was assessed in a 2-cm-diameter region near the ear ossicles, and standard deviation was measured for each of the seven decrements from the RD. As the radiation dose decreased, the noise progressively increased, and visual assessment scores progressively decreased. Acceptable image scores were obtained at six-sevenths (4.9), five-sevenths (4.8), four-sevenths (4.7), and three-sevenths (4.6) of the RD. Thus, acceptable porcine temporal bone CT images were obtained with a radiation dose reduction of approximately 50%. |
| キーワード | computed tomography photon-counting detector computed tomography ear ossicle energy-integrating detector computed tomography |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-04 |
| 巻 | 79巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 75 |
| 終了ページ | 80 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| JaLCDOI | 10.18926/AMO/68644 |
|---|---|
| フルテキストURL | 79_2_065.pdf |
| 著者 | Maki, Masatoshi| Takada, Ryo| Ishigo, Tomoyuki| Fujiwara, Miki| Takahashi, Yoko| Otsuka, Shinya| Tamura, Koji| Hamaoka, Terutaka| |
| 抄録 | Anamorelin (ANAM) is used to treat cancer-associated cachexia, a syndrome involving muscle loss and anorexia. The timing of the initiation of ANAM treatment is crucial to its efficacy. Although the body mass index (BMI) is a diagnostic criterion for cancer cachexia, no studies have explored its association with ANAM efficacy. We conducted a single-center, retrospective cohort study to investigate the association between the pre-treatment BMI and ANAM efficacy in patients with cancer-associated cachexia (n=47). The ANAM treatment was considered effective if the patient’s appetite improved within 30 days of treatment initiation. We calculated a BMI cutoff value (19.5 kg/m2) and used it to divide the patients into high- and low-BMI groups. Their background, clinical laboratory values, cancer types, and treatment lines were investigated. Twenty (42.6%) had a high BMI (≥ 19.5 kg/m2) and 27 (57.4%) had a low BMI (< 19.5 kg/m2). High BMI was significantly associated with ANAM effectiveness (odds ratio 7.86, 95% confidence interval 1.99-31.00, p=0.003). Together these results indicate that it is beneficial to initiate ANAM treatment before a patient’s BMI drops below 19.5 kg/m2. Our findings will help advance cancer cachexia treatment and serve as a reference for clinicians to predict ANAM’s efficacy. |
| キーワード | anamorelin cancer-associated cachexia body mass index albumin efficacy rate |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-04 |
| 巻 | 79巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 65 |
| 終了ページ | 73 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| JaLCDOI | 10.18926/AMO/68363 |
|---|---|
| フルテキストURL | 79_1_059.pdf |
| 著者 | Minakawa, Shun| Hirano, Masayuki| Takahashi, Kazuya| Imamura, Yuta| Watanabe, Takashi| |
| 抄録 | Intraorbital arteriovenous fistulas (IOAVFs) are rare vascular abnormalities. We describe a case of an IOAVF featuring a direct shunt between the accessory meningeal artery and the superior ophthalmic artery. A 55-year-old woman presented with a 1-month history of visual impairment in her right eye, and magnetic resonance imaging (MRI) revealed optic neuritis-like findings. Steroid pulse therapy temporarily resolved visual impairment. However, 1 month later, she experienced decreased visual acuity, ocular conjunctival hyperemia, edema, and a pulsatile murmur. Contrast-enhanced MRI and digital subtraction angiography revealed compression optic neuropathy due to an IOAVF. Following successful treatment with transarterial embolization, her symptoms disappeared. |
| キーワード | intraorbital arteriovenous fistula compressive optic neuropathy accessory meningeal artery superior ophthalmic vein |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-02 |
| 巻 | 79巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 59 |
| 終了ページ | 64 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 40012161 |
| Web of Science KeyUT | 001440463800008 |
| JaLCDOI | 10.18926/AMO/68362 |
|---|---|
| フルテキストURL | 79_1_051.pdf |
| 著者 | Miura, Taro| Kawasaki, Yoichi| Hamano, Hirofumi| Zamami, Yoshito| Sendo, Toshiaki| |
| 抄録 | Photoinitiators are used in the manufacture of many daily products, and may produce harmful effects due to their cytotoxicity. They have also been detected in human serum. Here, we investigated the histamine-producing effects in HMC-1 cells and the inflammatory cytokine release effects in RAW264 cells for four photoinitiators: 1-hydroxycyclohexyl phenyl ketone; 2-isopropylthioxanthone; methyl 2-benzoylbenzoate; and 2-methyl-4´-(methylthio)-2-morpholinopropiophenone. All four promoted histamine production in HMC-1 cells; however, they did not significantly affect the release of inflammatory cytokines in RAW264 cells. These findings suggest that these four photoinitiators induce inflammatory cytokine-independent histamine production, potentially contributing to histamine-mediated chronic inflammation in vitro. |
| キーワード | photoinitiator ink injection histamine inflammation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-02 |
| 巻 | 79巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 51 |
| 終了ページ | 58 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 40012160 |
| Web of Science KeyUT | 001440463800007 |
| JaLCDOI | 10.18926/AMO/68361 |
|---|---|
| フルテキストURL | 79_1_047.pdf |
| 著者 | Kojima, Kazunori| Ujikawa, Takuya| Ono, Toshiro| |
| 抄録 | We assessed the immediate effects of a home-based rehabilitation (HBR) program on the balance performance and toe-grip strength of 29 older adults (mean±SD age of 75.1±9.9; 16 males, 13 females) who were participating in HBR services provided by Japan’s nursing care insurance system. Their toe-grip strength and balance performance were measured before and after the HBR program. The subjects’ toe-grip strength was significantly improved after the treatment. The subjects who had had a stroke showed a significant improvement after HBR. Contrarily, no significant difference was observed in the subjects’ functional reach results or their one-leg standing time. These results indicate that the exercise regimen provided in the HBR program led to increased excitability of motor units and immediately enhanced the subjects’ toe-grip strength. |
| キーワード | home-based rehabilitation toe-grip strength balance performance |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-02 |
| 巻 | 79巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 47 |
| 終了ページ | 50 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 40012159 |
| Web of Science KeyUT | 001440463800006 |
| レファレンス | Kira K: The basic approach to determining the effects of cerebrovascular disease and in the maintenance phase of rehabilitation. Phys Ther Jpn (2011) 38: 246-248 (in Japanese).| Ito T: Role of physical therapists at the home health care. Phys Ther Jpn (2001) 28: 399-402 (in Japanese).| Kojima K, Nakayama T, Watanabe A, Yoshimura S, Yamaya T, Sato K, Doi A, Ogino T, Moriyasu N and Watanabe S: Activities of daily living and quality of life assessment during home-based rehabilitation. Jpn J Compr Rehabil Sci (2017) 8: 30-36.| Benvenuti F, Ferrucci L, Guralnik JM, Gangemi S and Baroni A: Foot pain and disability in older persons: an epidemiologic survey. J Am Geriatr Soc (1995) 43: 479-484.| Kojima K, Kamai D, Yamamoto A, Tsuchitani Y and Kataoka H: The Effect of toe-grasping exercises on balance ability in home-based rehabilitation: a randomized controlled trial by block randomization. Phys Ther Res (2021) 24: 272-279.| Elm E von, Altman DG, Egger M, Pocock SJ, Gøtzsche PC and Vandenbroucke JP: The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. Int J Surg (2014) 12: 1495-1499.| Uritani D, Fukumoto T and Matsumoto D: Intrarater and interrater reliabilities for a toe grip dynamometer. J Phys Ther Sci (2012) 24: 639-643.| Vellas BJ, Wayne SJ, Romero L, Baumgartner RN, Rubenstein LZ and Garry PJ: One-Leg Balance Is an important predictor of injurious falls in older persons. J Am Geriatr Soc (1997) 45: 735-738.| Duncan PW, Weiner DK, Chandler J and Studenski S: Functional Reach: A new clinical measure of balance. J Gerontol (1990) 45: M192-197.| Sale DG: Postactivation Potentiation: Role in human performance. Exer Sport Sci Rev (2002) 30: 138-143.| Gossen ER and Sale DG: Effect of postactivation potentiation on dynamic knee extension performance. Eur J Appl Physiol (2000) 83: 524-530.| Jones DA, Newham DJ and Torgan C: Mechanical influences on long-lasting human muscle fatigue and delayed-onset pain. J Physiol (1989) 412: 415-427.| Eston RG, Finney S, Baker S and Baltzopoulos V: Muscle tenderness and peak torque changes after downhill running following a prior bout of isokinetic eccentric exercise. J Sports Sci (1996) 14: 291-299.| Onuma R, Soutome Y, Asada Y, Kurihara Y, Fujino Y and Matsuda T: Immediate effect of exercise therapy using ʼspiderʼ for chronic stroke patients with hemiplegia. Rigakuryoho Kagaku (2020) 35: 791-795 (in Japanese).| |
| JaLCDOI | 10.18926/AMO/68360 |
|---|---|
| フルテキストURL | 79_1_039.pdf |
| 著者 | Takao, Shinichiro| Uotani, Koji| Misawa, Haruo| Tetsunaga, Tomoko| Shinohara, Kensuke| Yamane, Kentaro| Oda, Yoshiaki| Tsuji, Hironori| Kajiki, Yuya| Ozaki, Toshifumi| |
| 抄録 | Evaluating vertebral bone mass and quality in the elderly poses challenges due to degenerative changes. This study aims to elucidate the usefulness of the trabecular bone score (TBS) by examining the relationship between bone mineral density (BMD), TBS, and Hounsfield unit (HU) values. A retrospective analysis of 599 vertebrae from 152 patients (mean age 69.0 years; range 44-89; 74 males and 78 females) undergoing dual-energy X-ray absorptiometry (DXA) and CT scans was conducted. Vertebrae were categorized into three grades based on the degree of degeneration. The TBS was calculated from DXA images, and the HU value was measured by placing a region of interest on an axial image of the vertebral mid-body. One-way analysis of variance and Pearson’s correlation tests were employed to investigate the relationship between BMD and TBS or HU values. While lumbar BMD significantly increased (p<0.01) with degenerative changes, TBS and HU values showed no significant differences. The correlations between lumbar BMD and TBS values, and between BMD and HU values, were stronger without degenerative changes than with degenerative changes. Significantly different HU values were observed between the right and left sides of severely degenerated vertebrae. Severe degenerative changes, particularly those associated with sclerosis, may impact HU values. TBS exhibits greater potential than HU values as a complementary tool. |
| キーワード | trabecular bone score computed tomography Hounsfield unit lumbar degenerative change radiodensity |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-02 |
| 巻 | 79巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 39 |
| 終了ページ | 45 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 40012158 |
| Web of Science KeyUT | 001440463800005 |
| JaLCDOI | 10.18926/AMO/68353 |
|---|---|
| フルテキストURL | 79_1_001.pdf |
| 著者 | Thiha, Moe| Hikita, Takao| Nakayama, Masanori| |
| 抄録 | Endothelial cell polarity is fundamental to the organization and function of blood vessels, influencing processes such as angiogenesis, vascular stability, and response to shear stress. This review elaborates on the molecular mechanisms that regulate endothelial cell polarity, focusing on key players like the PAR polarity complex and Rho family GTPases. These pathways coordinate the front–rear, apical–basal and planar polarity of endothelial cells, which are essential for the proper formation and maintenance of vascular structures. In health, endothelial polarity ensures not only the orderly development of blood vessels, with tip cells adopting distinct polarities during angiogenesis, but also ensures proper vascular integrity and function. In disease states, however, disruptions in polarity contribute to pathologies such as coronary artery disease, where altered planar polarity exacerbates atherosclerosis, and cancer, where disrupted polarity in tumor vasculature leads to abnormal vessel growth and function. Understanding cell polarity and its disruption is fundamental not only to comprehending how cells interact with their microenvironment and organize themselves into complex, organ-specific tissues but also to developing novel, targeted, and therapeutic strategies for a range of diseases, from cardiovascular disorders to malignancies, ultimately improving patient outcomes. |
| キーワード | blood vessel endothelial cell cell polarity atherosclerosis cancer |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2025-02 |
| 巻 | 79巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 1 |
| 終了ページ | 7 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2025 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 40012154 |
| Web of Science KeyUT | 001440463800001 |
| タイトル（別表記） | Effects of parity on the associations between evacuation and psychological distress and cardiovascular disease among women after the Great East Japan Earthquake : A cross-sectional study of the Fukushima Health Management Survey |
|---|---|
| 著者 | 安川 純代| 江口 依里| 大平 哲也| 林 史和| 坂井 晃| 島袋 充生| 藤森 敬也| 三浦 至| 矢部 博興| 前田 正治| 安村 誠司| |
| 抄録 | Introduction : Women are more likely to be physically, mentally, and socially vulnerable after disasters because of the physical, socioeconomical, and lifestyle-related factors that are often related to their parity. Here, we analyzed the effects of women's parity on the association between evacuation and psychological distress, trauma reactions, and cardiovascular disease (CVD). Participants and Methods : The participants were residents living in 13 municipalities in the evacuation zone of Japan's Fukushima Prefecture after the March 11, 2011 Great East Japan Earthquake who responded to the Fukushima Health Management Survey in FY2012. A total of 30,709 women aged 40-90 years were included in the analyses. We performed a logistic regression analysis to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) adjusted for CVD risk factors. Results : A multivariate analysis revealed that among the parous women (n = 19,608), evacuation was associated with psychological distress (adjusted OR 1.30, 95%CI : 1.17-1.44), trauma reactions (OR 1.22, 95%CI : 1.11-1.35), and heart disease (OR 1.14, 95%CI : 1.03-1.26) compared to the non-evacuation status. Among the nulliparous women (n = 1,794), there was no association between the evacuation and any outcomes. Conclusion : The evacuation of individuals after the Great East Japan Earthquake was associated with psychological distress, trauma reactions, and heart disease, especially among parous women. |
| キーワード | 東日本大震災（the Great East Japan Earthquake） 大規模災害（large disaster） 出産歴（parity） 精神的苦痛（psychological distress） 循環器疾患（cardiovascular disease） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2024-12-02 |
| 巻 | 136巻 |
| 号 | 3号 |
| 開始ページ | 120 |
| 終了ページ | 126 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.136.120 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2024 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.136.120 |
| JaLCDOI | 10.18926/bgeou/67889 |
|---|---|
| タイトル（別表記） | Changing of Study and Training of Teachers in the Modern China: Its Process and Issues |
| フルテキストURL | bgeou_187_001_010.pdf |
| 著者 | 梶井 一暁| 孫 瑛鞠| 孫 長亮| |
| 抄録 | 中華人民共和国が成立し，中国政府は国民教育を担う教員の養成と研修（在職学習）に対する関心を強めた。初等中等教育の教員研修に関する政策を順次実施し，現職教員の量と質を管理しようとした。政府の教員研修への積極的関与は，教員の学びを分散から体系化へ，無秩序から標準化へと導く過程であった。その政策的展開を緊急需要期（1949-1984 年），模索・標準化期（1985-1999 年），発展・形成期（2000-2010 年），改善・確立期（2011-現在）という４つの時期整理にもとづいて考察する。そして，政府の強力指導と近年の情報技術活用による教員研修の推進は，全国的な教員研修の水準を形成したが，課題として，地域差，教員個々の経験や意欲の多様性などに対する取組の必要を気づかせるものであったことを指摘する。教員政策における標準化と多元化のせめぎあいが，現代中国の教員研修事情から看取される。 |
| キーワード | 中国 教員研修 初等中等教育 国培計画 培訓指南 評定 |
| 出版物タイトル | 岡山大学大学院教育学研究科研究集録 |
| 発行日 | 2024-12-06 |
| 巻 | 187巻 |
| 開始ページ | 1 |
| 終了ページ | 10 |
| ISSN | 1883-2423 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| JaLCDOI | 10.18926/AMO/67871 |
|---|---|
| フルテキストURL | 78_6_453.pdf |
| 著者 | Kawata, Yujiro| Watanabe, Kenta| Tokiya, Ryoji| Matsuno, Takeshi| Tanaka, Ryo| Taira, Naruto| Katsui, Kuniaki| |
| 抄録 | Radiation-induced angiosarcoma (RIAS) is a rare, late adverse event of radiotherapy comprising approximately half of all radiation-induced sarcomas. It has a relatively short latency period and generally unfavorable prognosis. This study presents a case of RIAS that developed 5 years and 11 months after the completion of hypofractionated radiotherapy (42.56 Gy/16 fractions) following partial mastectomy. The patient was diagnosed with RIAS 10 months after the onset of skin redness. She underwent skin tumor resection, followed by paclitaxel, then pazopanib administration, but no radiotherapy. At 6 years and 2 months after surgery, no RIAS recurrence has been detected. |
| キーワード | breast cancer hypofractionated radiotherapy radiation-induced angiosarcoma |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-12 |
| 巻 | 78巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 453 |
| 終了ページ | 458 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39719318 |
| Web of Science KeyUT | 001397808000001 |
| レファレンス | Early Breast Cancer Trialistsʼ Collaborative Group (EBCTCG), Darby S, McGale P, Correa C, Taylor C, Arriagada R, Clarke M, Cutter D, Davies C, Ewertz M, Godwin J, Gray R, Pierce L, Whelan T, Wang Y and Peto R: Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10, 801 women in 17 randomised trials. Lancet (2011) 378: 1707-1716.| Yamauchi C, Yoshimura M, Sekiguchi K, Hamamoto Y, Nakajima N, Sanuki N, Ogo E, Oguchi M, Saji S and Iwata H: The Japanese Breast Cancer Society Clinical Practice Guideline for radiation treatment of breast cancer, 2018 edition. Breast Cancer (2020) 27: 9-16.| Smith BD, Bellon JR, Blitzblau R, Freedman G, Haffty B, Hahn C, Halberg F, Hoffman K, Horst K, Moran J, Patton C, Perlmutter J, Warren L, Whelan T, Wright JL and Jagsi R: Radiation therapy for the whole breast: executive summary of an American Society for Radiation Oncology (ASTRO) evidence-based guideline. Pract Radiat Oncol (2018) 8: 145-152.| Cahan WG, Woodard HQ, Higinbotham NL, Stewart FW and Coley BL: Sarcoma arising in irradiated bone; report of 11 cases. Cancer (1948) 1: 3-29.| Veiga LHS, Vo JB, Curtis RE, Mille MM, Lee C, Ramin C, Bodelon C, Aiello Bowles EJ, Buist DSM, Weinmann S, Feigelson HS, Gierach GL and Berrington de Gonzalez A: Treatment-related thoracic soft tissue sarcomas in US breast cancer survivors: a retrospective cohort study. Lancet Oncol (2022) 23: 1451-1464.| Yap J, Chuba PJ, Thomas R, Aref A, Lucas D, Severson RK and Hamre M: Sarcoma as a second malignancy after treatment for breast cancer. Int J Radiat Oncol Biol Phys (2002) 52: 1231-1237.| Kirova YM, Vilcoq JR, Asselain B, Sastre-Garau X and Fourquet A: Radiation-induced sarcomas after radiotherapy for breast carcinoma: a large-scale single-institution review. Cancer (2005) 104: 856-863.| Ikawa T, Kuwabara Y, Nakata K, Kanayama N, Morimoto M, Miyashiro I and Konishi K: Risk of thoracic soft tissue sarcoma after breast cancer radiotherapy: a population-based cohort study in Osaka, Japan. J Radiat Res (2024) 65: 272-278.| Bougeard G, Renaux-Petel M, Flaman JM, Charbonnier C, Fermey P, Belotti M, Gauthier-Villars M, Stoppa-Lyonnet D, Consolino E, Brugières L, Caron O, Benusiglio PR, Bressac-de Paillerets B, Bonadona V, Bonaïti-Pellié C, Tinat J, Baert-Desurmont S and Frebourg T: Revisiting Li-Fraumeni Syndrome From TP53 Mutation Carriers. J Clin Oncol (2015) 33: 2345-2352.| Mito JK, Mitra D, Barysauskas CM, Mariño-Enriquez A, Morgan EA, Fletcher CDM, Raut CP, Baldini EH and Doyle LA: A comparison of outcomes and prognostic features for radiation-associated angiosarcoma of the breast and other radiation-associated sarcomas. Int J Radiat Oncol Biol Phys (2019) 104: 425-435.| Takehara Y, Matsuda N, Kobayashi D, Yoshida A, Takei J, Kanomata N, Tsunoda H, Yamauchi H and Hayashi N: Radiation-induced angiosarcoma of the breast: individual participant meta-analysis of Japanese population. Breast Cancer (2023) 30: 739-747.| Fowler JF: The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol (1989) 62: 679-694.| Wong HH, Cojocaru E, Watkins J, James S, Aloysius T, Harrington J, Horan G and Hatcher H: Radiation-induced angiosarcoma of the breast: retrospective analysis at a regional treatment centre. Breast Cancer (2024) 31: 272-282.| Mirjolet C, Diallo I, Bertaut A, Veres C, Sargos P, Helfre S, Sunyach MP, Truc G, Le Pechoux C, Paumier A, Ducassou A, Jolnerovski M, Thariat J, Lapeyre M, Cordoba A, Mahé MA and Maingon P: Treatment related factors associated with the risk of breast radio-induced-sarcoma. Radiother Oncol (2022) 171: 14-21.| Nozaki M, Kagami Y, Machida R, Nakamura K, Ito Y, Nishimura Y, Teshima T, Saito Y, Nagata Y, Matsumoto Y, Akimoto T, Hiraoka M, Japan Clinical Oncology Group and Radiation Therapy Study Group: Final analysis of a multicenter single-arm confirmatory trial of hypofractionated whole breast irradiation after breast-conserving surgery in Japan: JCOG0906. Jpn J Clin Oncol (2021) 51: 865-872.| Sheth GR, Cranmer LD, Smith BD, Grasso-Lebeau L and Lang JE: Radiation-induced sarcoma of the breast: a systematic review. Oncologist (2012) 17: 405-418.| Nakamura R, Nagashima T, Sakakibara M, Nakano S, Tanabe N, Fujimoto H, Arai M, Kadowaki M, Oide T, Tanizawa T and Miyazaki M: Angiosarcoma arising in the breast following breast-conserving surgery with radiation for breast carcinoma. Breast Cancer (2007) 14: 245-249.| Mergancová J, Lierová A, Coufal O, Žatecký J, Melichar B, Zedníková I, Mergancová J, Jesenková A, Št’astný K, Gatěk J, Kubala O, Prokop J, Dyttert D, Karaba M, Schwarzbacherová I, Humeňanská A, Šuk J, Valenta M, Moucha V, Sákra L, Hlávka A, Hácová M, Vojtíšek R, Sochor M, Jirásek T, Zábojníková M, Zemanová M, Macháleková K, Rusnáková D , K údelová E and Smolár M: Radiation-associated angiosarcoma of the breast: an international multicenter analysis. Surg Oncol (2022) 41: 101726.| Depla AL, Scharloo-Karels CH, de Jong MAA, Oldenborg S, Kolff MW, Oei SB, van Coevorden F, van Rhoon GC, Baartman EA, Scholten RJ, Crezee J and van Tienhoven G: Treatment and prognostic factors of radiation-associated angiosarcoma (RAAS) after primary breast cancer: a systematic review. Eur J Cancer (2014) 50: 1779-1788.| Goerdt LV, Schneider SW and Booken N: Cutaneous angiosarcomas: molecular pathogenesis guides novel therapeutic approaches. J Dtsch Dermatol Ges (2022) 20: 429-443.| Degnim AC, Siontis BL, Ahmed SK, Hoskin TL, Hieken TJ, Jakub JW, Baum CL, Day C, Schrup SE, Smith L, Carter JM, Sae Kho TM, Glazebrook KN, Vijayasekaran A, Okuno SH and Petersen IA: Trimodality therapy improves disease control in radiation-associated angiosarcoma of the breast. Clin Cancer Res (2023) 29: 2885-2893.| Ikenohira T, Konishi K, Hirata M, Ohira K and Nakamura K: Radical radiation therapy for radiation-induced angiosarcoma with local control. Case Rep Oncol (2021) 14: 1779-1784.| Ihara H, Kaji T, Katsui K, Miyake T, Waki T, Katayama N, Matsuzaki H, Yamasaki O, Kuroda M, Morizane S and Kanazawa S: Single institutional experience of radiation therapy for angiosarcoma of the scalp without cervical lymph node metastases: impact of concurrent chemoradiation with maintenance chemotherapy using taxanes on patient prognosis. Mol Clin Oncol (2019) 11: 498-504.| |
| JaLCDOI | 10.18926/AMO/67869 |
|---|---|
| フルテキストURL | 78_6_439.pdf |
| 著者 | Yamashita, Mampei| Tanaka, Takayuki| Sumida, Yorihisa| Yamazaki, Shoto| Hara, Yuki| Fukuda, Akiko| Hisanaga, Makoto| Wakata, Koki| Araki, Masato| Eguchi, Susumu| |
| 抄録 | Gangrenous cholecystitis (GC) is classified as moderate acute cholecystitis according to the Tokyo Guidelines from 2018 (TG18). We evaluated the risk factors for GC and the outcomes of early cholecystectomy. A total of 136 patients who underwent emergency cholecystectomy for acute cholecystitis were retrospectively analyzed; 58 of these patients (42.6%) were diagnosed with GC (GC group) based on our retrospective pathologic diagnosis. We comparatively evaluated the patient backgrounds and surgical outcomes between the GC group and non-GC group. The GC group was significantly older and included more hypertensive patients than the non-GC group. The GC group was prescribed more antibiotics as initial treatment than the non-GC group, and they had more days between onset and surgery. The preoperative white blood cell count and C-reactive protein values were significantly higher in the GC group than in the non-GC group, and these values were predictive factors for GC. Cholecystectomy required a longer operation time and caused greater blood loss in the GC group. The GC group also had longer hospitalization times than the non-GC group; however, no significant differences were observed in terms of postoperative complications. In conclusion, gangrenous changes should be assessed when diagnosing cholecystitis, and appropriate treatment, such as surgery or drainage, should be undertaken. |
| キーワード | gangrenous cholecystitis acute cholecystitis laparoscopic cholecystectomy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-12 |
| 巻 | 78巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 439 |
| 終了ページ | 447 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39719316 |
| Web of Science KeyUT | 001397799300002 |
| JaLCDOI | 10.18926/AMO/67868 |
|---|---|
| フルテキストURL | 78_6_429.pdf |
| 著者 | Kubota, Risa| Bekku, Kensuke| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Tomoko| Kobayashi, Yasuyuki| Araki, Motoo| |
| 抄録 | Although partial nephrectomy (PN) is preferred over radical nephrectomy (RN) for preserving renal function in patients with cT1 renal cancer, its impact on cardiovascular events (CVe) remains controversial. This study aimed to compare PN and RN in regard to the occurrence of CVe, including cerebrovascular events and exacerbation of hypertension (HT). We retrospectively analyzed 418 consecutive patients who underwent PN or RN for cT1 renal cancer. Propensity score-matching analysis was used to adjust for imbalances between patients who underwent PN and RN, leaving 102 patients in each group. The 5-year probability of cumulative CVe incidence was 6% in the PN group and 12% in the RN group (p=0.03), with a median follow-up of 73.5 months. The statistical significance was retained after propensity score matching for patients without preoperative proteinuria (p=0.03). For all CVe including cerebrovascular events and exacerbation of HT analyzed, PN provided a lower probability of occurrence than RN in patients with small renal cancers. |
| キーワード | chronic kidney disease hypertension nephrectomy proteinuria |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-12 |
| 巻 | 78巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 429 |
| 終了ページ | 437 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39719315 |
| Web of Science KeyUT | 001397799300001 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Hirai, Kenta| Sawada, Ryusuke| Hayashi, Tomohiro| Araki, Toru| Nakagawa, Naomi| Kondo, Maiko| Yasuda, Kenji| Hirata, Takuya| Sato, Tomoyuki| Nakatsuka, Yuki| Yoshida, Michihiro| Kasahara, Shingo| Baba, Kenji| Oh, Hidemasa| the TICAP/PERSEUS Study Group| |
| キーワード | cardiosphere heart failure restricted mean survival time single ventricle survival |
| 発行日 | 2024-11-19 |
| 出版物タイトル | Journal of the American Heart Association |
| 巻 | 13巻 |
| 号 | 22号 |
| 出版者 | Wiley |
| 開始ページ | e038137 |
| ISSN | 2047-9980 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 39526355 |
| DOI | 10.1161/JAHA.124.038137 |
| Web of Science KeyUT | 001357841000001 |
| 関連URL | isVersionOf https://doi.org/10.1161/JAHA.124.038137 |
| JaLCDOI | 10.18926/AMO/67666 |
|---|---|
| フルテキストURL | 78_5_413.pdf |
| 著者 | Kashihara, Kenichi| Irisawa, Minoru| Takao, Wataru| |
| 抄録 | We investigated patients with migraine or migraine variants who exhibited focal cerebral hypoperfusion on arterial spin-labeled (ASL) magnetic resonance (MR) imaging along with neurological symptoms. Fourteen patients with migraine demonstrated focal cerebral hypoperfusion. Three other patients did not have a history of recurrent headaches but exhibited comparable cerebral hypoperfusion to migraine patients on ASL-MRI in addition to neurological symptoms. Patients with migraine may present with neurological symptoms associated with cortical spreading depression during, after, or even without a headache phase. Additionally, the isolated neurological symptoms may be caused by a pathophysiology identical to that of migraine but without presenting with recurrent headaches. |
| キーワード | arterial spin-labeled magnetic resonance imaging cortical spreading depression migraine complex migraine without headache vertigo |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 413 |
| 終了ページ | 421 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467660 |
| JaLCDOI | 10.18926/AMO/67664 |
|---|---|
| フルテキストURL | 78_5_401.pdf |
| 著者 | Toyota, Yusuke| Uda, Kazuhiro| Shirabe, Komei| Moriwake, Tadashi| |
| 抄録 | Severe febrile thrombocytopenia syndrome (SFTS) is a tick-borne infectious disease that is endemic in parts of eastern Asia. Few pediatric cases have been reported. We describe a case of SFTS in a seven-year-old girl who presented with prolonged fever and gastrointestinal symptoms. Leukopenia and thrombocytopenia on hematology, and a history of outdoor activity led us to diagnose SFTS, although the patient had no tick bite marks. We also review the literature and discuss the characteristics of pediatric SFTS. Physicians should consider SFTS in the differential diagnosis of fever with thrombocytopenia in children living in endemic areas. |
| キーワード | child tick-borne disease severe febrile thrombocytopenia syndrome zoonoses |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 401 |
| 終了ページ | 405 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467658 |
| JaLCDOI | 10.18926/AMO/67663 |
|---|---|
| フルテキストURL | 78_5_387.pdf |
| 著者 | Naoe, Shota| Tanaka, Ayumi| Kanzaki, Norie| Takenaka, Reiju| Sakoda, Akihiro| Miyaji, Takaaki| Yamaoka, Kiyonori| Kataoka, Takahiro| |
| 抄録 | Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation. |
| キーワード | radon inhalation proteomics multivariate analysis brain oxidative stress |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-10 |
| 巻 | 78巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 387 |
| 終了ページ | 399 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 39467657 |
| Web of Science KeyUT | 001343346400005 |