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タイトル(別表記) Questionnaire survey of junior and mid-career otolaryngologists' attitudes towards clinical research
著者 浦口 健介| 頼藤 貴志| 高尾 総司| 菅谷 明子| 安藤 瑞生|
抄録  Introduction : Clinical research is crucial for the advancement of medicine, but modern otolaryngologists' attitudes regarding clinical research have not been known. This study was conducted to survey the background, knowledge, and interest in clinical research among junior and mid-career otolaryngologists.
 Methods : A questionnaire survey was distributed to 34 otolaryngologists with ≤15 years' clinical experience working at Okayama University and its affiliated facilities. The respondents were divided into junior (non-specialists) and mid-career otolaryngologists (specialists) based on whether they were board-certified otolaryngologists. The survey assessed their background, understanding, and interest in clinical research.
 Results : Twenty-nine otolaryngologists (83%) responded (10 junior and 19 mid-career otolaryngologists). There was significant individual variation in their interest and knowledge of clinical research. However, approximately half of the respondents indicated that they were not interested in and/or had never engaged in clinical research.
 Conclusion : The data collected by this survey contribute to our understanding of the current state of clinical research engagement among junior and mid-career otolaryngologists, and they can serve as a basis for exploring future strategies to increase this engagement.
キーワード 臨床研究 (clinical research) 統計解析 (statistical analysis) ビッグデータ (bigdata) 質問紙調査 (questionnaire survey)
出版物タイトル 岡山医学会雑誌
発行日 2025-04-01
137巻
1号
開始ページ 20
終了ページ 24
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.137.20
言語 日本語
著作権者 Copyright (c) 2025 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.137.20
タイトル(別表記) The potential and prospects of organ generation medicine
著者 森 宗昌|
キーワード organ generation regeneration bioengineering
出版物タイトル 岡山医学会雑誌
発行日 2025-04-01
137巻
1号
開始ページ 15
終了ページ 19
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.137.15
言語 日本語
著作権者 Copyright (c) 2025 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.137.15
JaLCDOI 10.18926/ESR/68676
タイトル(別表記) Improved sedimentary layer model including the accretionary prism in the fore-arc region of the Ryukyu arc, Japan
フルテキストURL esr_031_001_015.pdf
著者 小松 正直| 浦上 想平| 岡元 太郎| 竹中 博士|
抄録  We combine the recent seismic reflection profiles to construct a new seismic velocity model of the sedimentary layer incorporating the accretionary prism along the Ryukyu trench. In constructing the new model, we refer to the zoning (ZONE1 to ZONE4) identified by Okamura et al. (2017, Tectonophys.). The construction process consists of the following steps: First, we digitize either unconformities or VP=4 to 5 km/s lines as the seismic basement, whichever is more clearly identifiable. Second, the digitized thickness data of the sedimentary layer from the reflection profiles are geometrically modeled and interpolated to make the three-dimensional structure model. Finally, we supplement the external region of the constructed 3-D sedimentary model using the J-SHIS model provided by the NIED to complete the velocity structure model in the entire Ryukyu arc. The main features of our model are as follows: In ZONE1, off Ishigaki-jima island, the thick sedimentary layer extends about 50 km wide from the Ryukyu trench. In ZONE2, off Miyako-jima island, the thinner layer compared to the other zones is found near the trench, with a thin sedimentary terrace covering the area behind it. In ZONE3, off Okinawa-jima island, the sedimentary layer deepens as it approaches the trench. In ZONE4, off Tokara islands, the deepest layer among all zones is identified. We then conduct 3-D finite-difference simulations of seismic wave propagation using the new and the previous models to confirm the improvement of the new model. In the simulations, the effects of the accretionary prism along the Ryukyu trench on the seismic wave propagation are clearly identified.
キーワード Sedimentary layer model Accretionary prism Ryukyu arc
出版物タイトル Okayama University Earth Science Report
発行日 2025-03-31
31巻
1号
開始ページ 1
終了ページ 15
ISSN 1340-7414
言語 日本語
著作権者 © 2025 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
論文のバージョン publisher
著者 Ozato, Toshiki| Kono, Yoshiyasu| Horiguchi, Shigeru| Tsutsumi, Koichiro| Yamamoto, Hideki| Hirasawa, Akira| Ennishi, Daisuke| Tomida, Shuta| Toyooka, Shinichi| Otsuka, Motoyuki|
キーワード Homologous recombination repair Small bowel adenocarcinoma Genome
備考 © 2025 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Apr. 2026.|
発行日 2025-05-02
出版物タイトル European Journal of Cancer
220巻
出版者 Elsevier BV
開始ページ 115401
ISSN 0959-8049
NCID AA1075407X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2025 Elsevier Ltd.
論文のバージョン author
PubMed ID 40188744
DOI 10.1016/j.ejca.2025.115401
Web of Science KeyUT 001465491700001
関連URL isVersionOf https://doi.org/10.1016/j.ejca.2025.115401
フルテキストURL fulltext.pdf
著者 Shinaoka, Akira| Kimata, Yoshihiro|
キーワード Lymphedema Lymphatic function Lymph flow Chylothorax Chylous ascites,lymph velocity
発行日 2025-04-24
出版物タイトル Scientific Reports
15巻
1号
出版者 Nature Portfolio
開始ページ 14323
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2025
論文のバージョン publisher
PubMed ID 40275043
DOI 10.1038/s41598-025-99416-8
Web of Science KeyUT 001475676100005
関連URL isVersionOf https://doi.org/10.1038/s41598-025-99416-8
フルテキストURL fulltext.pdf
著者 Ando, Yushin| Kobo, Akinao| Niwa, Tatsuya| Yamakawa, Ayako| Konoma, Suzuna| Kobayashi, Yuki| Nureki, Osamu| Taguchi, Hideki| Itoh, Yuzuru| Chadani, Yuhei|
発行日 2025-03-08
出版物タイトル Nature Communications
16巻
1号
出版者 Nature Portfolio
開始ページ 2323
ISSN 2041-1723
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2025
論文のバージョン publisher
PubMed ID 40057501
DOI 10.1038/s41467-025-57659-z
Web of Science KeyUT 001462675700032
関連URL isVersionOf https://doi.org/10.1038/s41467-025-57659-z
フルテキストURL fulltext.pdf
著者 Kong, Dezheng| Funabiki, Nobuo| Fang, Shihao| Noprianto, Mitsuhiro| Okayasu, Mitsuhiro| Puspitaningayu, Pradini|
キーワード creep test Raspberry Pi dial gauge needle reading smart lighting
発行日 2025-04-02
出版物タイトル Technologies
13巻
4号
出版者 MDPI
開始ページ 139
ISSN 2227-7080
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2025 by the authors.
論文のバージョン publisher
DOI 10.3390/technologies13040139
Web of Science KeyUT 001474287400001
関連URL isVersionOf https://doi.org/10.3390/technologies13040139
フルテキストURL fulltext.pdf
著者 Tokushige, Keisuke| Asai, Shota| Abe, Takumi|
キーワード 3,3-dialkoxyisatins isatins ketalization iodine indole alkaloid
発行日 2025-03-17
出版物タイトル Chemistry
7巻
2号
出版者 MDPI
開始ページ 43
ISSN 2624-8549
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2025 by the authors.
論文のバージョン publisher
DOI 10.3390/chemistry7020043
Web of Science KeyUT 001474407600001
関連URL isVersionOf https://doi.org/10.3390/chemistry7020043
フルテキストURL fulltext.pdf
著者 Yoshida, Masashi| Ejiri, Kentaro| Matsuo, Naoaki| Naito, Takanori| Kuroda, Kazuhiro| Tokioka, Koji| Hatanaka, Kunihiko| Fujimoto, Ryohei| Yamaoka, Hidenaru| Kajikawa, Yutaka| Suruga, Kazuki| Sugiyama, Hiroki| Miyaji, Tsuyoshi| Morimoto, Yoshimasa| Okamura, Nobuhiro| Sarashina, Toshihiro| Akagi, Satoshi| Miyoshi, Toru| Nakamura, Kazufumi| Ito, Hiroshi| Yuasa, Shinsuke|
キーワード Factor Xa inhibitors Anticoagulation effects Cancer Venous thromboembolism
発行日 2025-04-16
出版物タイトル Thrombosis Journal
23巻
1号
出版者 BMC
開始ページ 36
ISSN 1477-9560
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2025.
論文のバージョン publisher
PubMed ID 40241057
DOI 10.1186/s12959-025-00720-0
Web of Science KeyUT 001469332700001
関連URL isVersionOf https://doi.org/10.1186/s12959-025-00720-0
フルテキストURL fulltext.pdf
著者 Umeda, Hibiki| Shigeyasu, Kunitoshi| Takahashi, Toshiaki| Moriwake, Kazuya| Kondo, Yoshitaka| Yoshida, Kazuhiro| Takeda, Sho| Yano, Shuya| Matsumi, Yuki| Kishimoto, Hiroyuki| Fuji, Tomokazu| Yasui, Kazuya| Yamamoto, Hideki| Takagi, Kosei| Kayano, Masashi| Michiue, Hiroyuki| Nakamura, Keiichiro| Mori, Yoshiko| Teraishi, Fuminori| Tazawa, Hiroshi| Umeda, Yuzo| Kagawa, Shunsuke| Goel, Ajay| Fujiwara, Toshiyoshi|
キーワード RNA-editing Macrophage Chemoresistance Biomarker Colorectal cancer
発行日 2025-04-16
出版物タイトル Molecular Cancer
24巻
1号
出版者 BMC
開始ページ 116
ISSN 1476-4598
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2025.
論文のバージョン publisher
PubMed ID 40241135
DOI 10.1186/s12943-025-02312-y
Web of Science KeyUT 001470204500003
関連URL isVersionOf https://doi.org/10.1186/s12943-025-02312-y
フルテキストURL fulltext.pdf
著者 Kamio, Tomohiro| Kono, Yoshiyasu| Hirosuna, Kensuke| Ozato, Toshiki| Yamamoto, Hideki| Hirasawa, Akira| Ennishi, Daisuke| Tomida, Shuta| Toyooka, Shinichi| Otsuka, Motoyuki|
キーワード comprehensive genomic profiling early-onset gastric cancer oxaliplatin TP53
発行日 2025-04-18
出版物タイトル Cancer Medicine
14巻
8号
出版者 Wiley
開始ページ e70793
ISSN 2045-7634
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2025 The Author(s).
論文のバージョン publisher
PubMed ID 40249206
DOI 10.1002/cam4.70793
Web of Science KeyUT 001469550900001
関連URL isVersionOf https://doi.org/10.1002/cam4.70793
フルテキストURL fulltext.pdf
著者 Kuraoka, Sakiko| Kawano, Seiji| Ino, Shoko| Satomi, Takuya| Hamada, Kenta| Kono, Yoshiyasu| Iwamuro, Masaya| Kawahara, Yoshiro| Tanaka, Takehiro| Okada, Hiroyuki| Otsuka, Motoyuki|
キーワード autoimmune gastritis eradication gastric cancer Helicobacter pylori
発行日 2025-02-01
出版物タイトル Internal Medicine
64巻
3号
出版者 Japanese Society of Internal Medicine
開始ページ 343
終了ページ 350
ISSN 0918-2918
NCID AA10827774
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 Ⓒ 2025 The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 38960692
DOI 10.2169/internalmedicine.3617-24
Web of Science KeyUT 001470394600003
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.3617-24
フルテキストURL fulltext.pdf
著者 Sudo, Ryutaro| Miyamoto, Kohta| Ido, Hirofumi|
キーワード Laminated veneer lumber (LVL) Partial compressive load Bearing strength Embedment strength Partial compression perpendicular to grain (PCPG) Adhesive layer
発行日 2025-04-19
出版物タイトル Journal of Wood Science
71巻
1号
出版者 Springer
開始ページ 19
ISSN 1435-0211
NCID AA11200007
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2025.
論文のバージョン publisher
DOI 10.1186/s10086-025-02195-z
Web of Science KeyUT 001469993800002
関連URL isVersionOf https://doi.org/10.1186/s10086-025-02195-z
フルテキストURL fulltext.pdf
著者 Honda, Manami| Iwamuro, Masaya| Tanaka, Takehiro| Yamasaki, Yasushi| Kawano, Seiji| Hiraoka, Sakiko| Kawahara, Yoshiro| Otsuka, Motoyuki|
キーワード colonoscopy esophagogastroduodenoscopy gastrointestinal neoplasms gastrointestinal stromal tumor neurofibromatosis
発行日 2025-04-16
出版物タイトル JGH Open
9巻
4号
出版者 Wiley
開始ページ e70151
ISSN 2397-9070
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2025 The Author(s).
論文のバージョン publisher
PubMed ID 40247846
DOI 10.1002/jgh3.70151
Web of Science KeyUT 001468535400001
関連URL isVersionOf https://doi.org/10.1002/jgh3.70151
フルテキストURL eriseki_41.pdf
著者 木村 理| 山口 雄治| 宇田津 徹朗| 田﨑 博之| 那須 浩郎| 白石 純|
出版物タイトル 岡山大学構内遺跡発掘調査報告
発行日 2025-03-21
41巻
言語 日本語
論文のバージョン publisher
Pages 86p. 14図版
タイトル(別表記) Bulletin of Cultural Heritage Management Division Research Institute for the Dynamics of Civilizations Okayama University 2023
フルテキストURL barc_2023.pdf
著者 柴田 亮| パレオ・ラボAMS年代測定グループ| 木村 理| 野﨑 貴博| 山口 雄治| 岩﨑 志保|
出版物タイトル 岡山大学文明動態学研究所文化遺産マネジメント部門紀要
発行日 2025-02-20
2023巻
ISSN 2758-9625
言語 日本語
著作権者 ⒸCultural Heritage Management Division, Research Institute for the Dynamics of Civilizations, Okayama University
論文のバージョン publisher
Pages vi, 80 p.
JaLCDOI 10.18926/AMO/68654
フルテキストURL 79_2_139.pdf
著者 Takeda, Yasushige| Noma, Kazuhiro| Maeda, Naoaki| Mizusawa, Yohei| Matsumoto, Hijiri| Kondo, Yuhei| Kunitomo, Tomoyoshi| Tanoue, Yukinori| Hashimoto, Masashi| Tanabe, Shunsuke| Fujiwara, Toshiyoshi|
抄録 In thoracic esophageal cancer, lymph node dissection around the recurrent laryngeal nerve is crucial but poses a risk of nerve palsy, affecting postoperative quality of life. In cases with an aberrant right subclavian artery (ARSA), the right recurrent laryngeal nerve is absent, and the non-recurrent inferior laryngeal nerve (NRILN) enters the larynx directly from the vagus nerve in the cervical region. Identifying the course of the NRILN is vital to avoid injury. A case of esophageal cancer with an ARSA, in which the course of the NRILN was preserved using the Nerve Integrity Monitoring (NIM) system during surgery, is described.
キーワード esophageal cancer intraoperative nerve monitoring aberrant right subclavian artery non-recurrent inferior laryngeal nerve thoracoscopic esophagectomy
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2025-04
79巻
2号
出版者 Okayama University Medical School
開始ページ 139
終了ページ 144
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン publisher
査読 有り
JaLCDOI 10.18926/AMO/68652
フルテキストURL 79_2_129.pdf
著者 Tsuji, Akihiro| Shiode, Yusuke| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Morita, Tetsuro| Takahashi, Kosuke| Morizane, Yuki|
抄録 A 66-year-old woman presented with significant anterior capsule contraction and intraocular lens dislocation in both eyes 4 months after cataract surgery. Postoperative examinations such as fluorescein angiography, Goldmann perimetry, and electroretinography revealed retinitis pigmentosa (RP). Patients with significant anterior capsule contraction after cataract surgery should be closely examined because RP may be a contributing factor.
キーワード retinitis pigmentosa intraocular lens anterior capsule contraction
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2025-04
79巻
2号
出版者 Okayama University Medical School
開始ページ 129
終了ページ 134
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン publisher
査読 有り
JaLCDOI 10.18926/AMO/68649
フルテキストURL 79_2_109.pdf
著者 Awai, Kyoko| Nakatsuka, Mikiya|
抄録 The status of postpartum depression was elucidated herein with the use of the Edinburgh Postnatal Depression Scale (EPDS) in women in Shikoku, Japan who became pregnant and gave birth after undergoing infertility treatment, including assisted reproductive technology (ART). The assessment was performed during their children’s 4-month health examination. The relationships between postpartum depression and the mothers’ background factors and scores on the Big Five personality traits scale were also examined. Of the Big Five personality traits, the scores for neuroticism were significantly higher in the ART group (n=71) than in the general infertility treatment (n=118) and natural pregnancy (n=872) groups. No significant differences in EPDS scores were seen among these three groups. A logistic regression analysis showed that neuroticism was associated with an EPDS score ≧9 points, (which is suggestive of postpartum depression, ) in all groups. Moreover, although a long-standing marriage had an inhibitory effect on postpartum depression in the natural pregnancy group, no such trend was seen in the ART group, which included many women with long-standing marriages. Particularly for women who become pregnant by ART, an individualized response that pays close attention to the woman’s personality traits is needed.
キーワード infertility treatment assisted reproductive technology postpartum postpartum depression personality trait
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2025-04
79巻
2号
出版者 Okayama University Medical School
開始ページ 109
終了ページ 116
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン publisher
査読 有り
JaLCDOI 10.18926/AMO/68648
フルテキストURL 79_2_101.pdf
著者 Isozaki, Hiroshi| Matsumoto, Sasau| Takama, Takehiro| Isozaki, Yuka|
抄録 To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surgery (2005-2022) at our hospital. In this cohort, 53% (278/521) of the patients who underwent breast conservative surgery (BCS) and 96% (124/129) of those treated with mastectomy did not receive POI. The patients who underwent BCS were treated with POI using opposing tangential field irradiation. A false negative (FN) SLN was retrospectively defined as a negative metastasis in SLN plus positive recurrence in the axillary lymph nodes. Recurrence was detected in 83 patients. A logistic regression analysis revealed that the nuclear grade (odds ratio [OR] 1.69), POI (OR 0.41), and postoperative hormone therapy (OR 0.40) were each significantly related to recurrence. The 26.1% (12/46) FN rate of the non-POI patients decreased to 5.8% (1/17) compared to those treated with POI. The rate of axillary recurrence was significantly lower in the POI group (0.4%) versus the non-POI group (2.7%) (p=0.0355). The rate of locoregional recurrence was also significantly lower in the POI group (2.0%) versus the non-POI group (13.4%) (p<0.0001). No significant difference was observed in the rate of distant recurrence between the POI (4.0%) and non-POI (3.3%) (p=0.831) groups. These results indicated that the postoperative opposing tangential field irradiation of conserved breast tissue inhibited recurrence in the axillary lymph nodes.
キーワード breast cancer postoperative irradiation radiation therapy sentinel lymph nodes recurrence
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2025-04
79巻
2号
出版者 Okayama University Medical School
開始ページ 101
終了ページ 107
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン publisher
査読 有り