検索条件

閉じる

検索結果 9730 件

JaLCDOI 10.18926/ATM/61436
フルテキストURL 75_1_63.pdf
著者 Tada, Katsuhiko| Miyagi, Yasunari| Nakamura, Kazue| Yorozu, Moe| Fukushima, Emi| Kumazawa, Kazumasa| Nakamura, Makoto| Kageyama, Misao|
抄録 We used a differential equation to identify the biological relationship between the maternal prepregnancy body mass index (BMI) and lactation on postpartum day 4 in Japanese women with neonatal separation. This retro-spective observational study included 252 mothers (135 primiparas, 117 multiparas) whose singleton neonates were admitted to a neonatal ICU. We formulated hypotheses based on breast anatomy to analyze the relation-ship between the expressed milk obtained on postpartum day 4 and the maternal prepregnancy BMI with the following differential equation: y’(x) = k y(x)/x, where k is the constant, x is the prepregnancy BMI, and y is the expressed milk volume. The formula was then obtained as y(x) = axk, where a is the constant. The Akaike information criterion (AIC) was used to estimate the regression equation with the maximum likelihood for primiparas and multiparas. The best criteria for BMI determined by the AIC were 20.89 kg/m2 in primiparas and 20.19 kg/m2 in multiparas. These were the optimal BMI values for lactation, coinciding with the median prepregnancy BMI in the study population (20.78 kg/m2 in primiparas and 20.06 kg/m2 in multiparas). The formula based on biomathematics might help establish the biological relationship between prepregnancy BMI and breastmilk volume.
キーワード biomathematics body mass index expressed milk lactation
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 63
終了ページ 69
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649615
JaLCDOI 10.18926/AMO/61433
フルテキストURL 75_1_45.pdf
著者 Otsuka, Hiroaki| Miyoshi, Toru| Ejiri, Kentaro| Kohno, Kunihisa| Nakahama, Makoto| Doi, Masayuki| Munemasa, Mitsuru| Murakami, Masaaki| Nakamura, Kazufumi| Ito, Hiroshi|
抄録 Remote ischemic preconditioning (RIPC) is a promising strategy for protecting against ischemic reperfusion injury. This study is a secondary analysis of a randomized study that aimed to evaluate the effect of RIPC on the early increase in serum creatinine (SCr) following percutaneous coronary intervention (PCI), which is associ-ated with contrast-induced acute kidney injury. Patients with stable angina undergoing elective PCI were assigned to control, RIPC, and continuous infusion of nicorandil (nicorandil) groups. The endpoint of this study was the incidence of the early increase in SCr, a predictor of contrast-induced acute kidney injury, which was defined as either a > 20% or absolute increase by 0.3 mg/dl of SCr levels after 24 h of PCI. This study included 220 patients for whom a dataset of SCr values was available. The incidence of the early increase in SCr was significantly lower in the RIPC than in the control (1.3% vs 10.8%, p = 0.03) group, but was not significantly different between the nicorandil and control groups. In multivariate analysis, RIPC remained a significant fac-tor associated with a reduction in the incidence of early increase in SCr. RIPC reduces the incidence of early increase in SCr in patients with stable angina following elective PCI.
キーワード remote ischemic preconditioning stable angina serum creatinine acute kidney injury
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 45
終了ページ 53
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649613
JaLCDOI 10.18926/AMO/61432
フルテキストURL 75_1_39.pdf
著者 Akezaki, Yoshiteru| Nakata, Eiji| Kikuuchi, Masato| Tominaga, Ritsuko| Kurokawa, Hideaki| Hamada, Makiko| Aogi, Kenjiro| Ohsumi, Shozo| Sugihara, Shinsuke|
抄録 In this study, we examined whether axillary web syndrome (AWS) in patients with breast cancer following axil-lary lymph node dissection affects range of motion (ROM), upper extremity function, and quality of life (QOL). The risk factors for AWS were also evaluated in a total of 238 consecutive breast cancer patients follow-ing axillary lymph node dissection. At 1, 2, and 3 months after surgery, there were no significant differences between the AWS group and the non-AWS group in upper-limb function or QOL. At 2 months after surgery, shoulder flexion and abduction ROM were significantly higher in the AWS group than in the non-AWS group (p < 0.05). Self-training time at home was not significantly different between the groups at 1, 2, or 3 months. Only age was a significant predictor of AWS at 1 month after surgery (p < 0.05). The AWS group in the present study did not have worse results for shoulder joint ROM, upper-limb function, and QOL than the non-AWS group. Younger age should be useful for predicting the development of AWS in the early postoperative period.
キーワード breast cancer axillary web syndrome age upper limb function quality of life
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 39
終了ページ 44
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649612
JaLCDOI 10.18926/AMO/61431
フルテキストURL 75_1_31.pdf
著者 Miyamaru, Satoru| Murakami, Daizo| Nishimoto, Kohei| Saito, Haruki| Miyamoto, Yusuke| Hirota, Kaoruko| Ise, Momoko| Orita, Yorihisa|
抄録 Although the lung is the most common site of distant metastases from head and neck squamous cell carcinoma (HNSCC), the number of reports about the effects of pulmonary metastasectomy for the treatment of lung metastasis from HNSCC is limited. Metachronous pulmonary metastases were detected in 45 HNSCC patients at Kumamoto University Hospital from 1998 to 2018. Twenty-two patients underwent an operative resection (Ope group) and 23 underwent chemotherapy (Chemo group). The 3-year overall survival (OS) rate and median OS were evaluated. The effects of adjuvant chemotherapy after pulmonary metastasectomy and of new drugs (cetuximab and nivolumab), in the chemo group were also assessed. The 3-year OS rates and median OS were: Ope, 66.1% and 31.5 months; Chemo, 39.7% and 18 months, respectively. In the Ope group, addi-tional recurrences were significantly fewer in the patients who underwent adjuvant chemotherapy post-surgery versus the patients who underwent surgery alone (p = 0.013). In the Chemo group, the 3-year OS rate of the patients who received new drugs was significantly better than that of the patients who did not (p = 0.021). Adjuvant chemotherapy after pulmonary metastasectomy may be a preferable treatment option for preventing recurrences. Cetuximab and nivolumab have a potential to improve OS.
キーワード pulmonary metastasis head and neck squamous cell carcinoma pulmonary metastasectomy adjuvant chemotherapy
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 31
終了ページ 37
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649611
JaLCDOI 10.18926/AMO/61430
フルテキストURL 75_1_25.pdf
著者 Tetsunaga, Tomonori| Tetsunaga, Tomoko| Yamada, Kazuki| Sanki, Tomoaki| Kawamura, Yoshi| Ozaki, Toshifumi|
抄録 In bipolar hemiarthroplasty (BHA), it is important to preserve soft tissue to reduce the risk of postoperative dislocation. A variety of surgical approaches for BHA are available, but extra care is needed with muscle- and tendon-preserving approaches in geriatric patients. We investigated the usefulness of BHA using a conjoined tendon-preserving posterior (CPP) approach, in which only the external obturator muscle is dissected, in geri-atric patients. We retrospectively analyzed the cases of 40 femoral neck fracture patients (10 men, 30 women) aged ≥ 80 years who underwent BHA using the CPP approach. The patients’ average age was 85.8 years (80-94 years). We examined the operation time, bleeding, preservation of short external rotator muscles, complica-tions, and stem alignment and subsidence from postoperative radiographs. Although gemellus inferior muscle injury was detected in 4 patients (10%), the hip joint stability was very excellent in all cases. There was no intraoperative fracture or postoperative dislocation. On postoperative radiographs, all femoral stems were in a neutral position. There was no stem subsidence in all 40 patients. BHA using the CPP approach appeared to be useful even in geriatric patients.
キーワード bipolar hip arthroplasty geriatric patient conjoined tendon-preserving posterior approach
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 25
終了ページ 30
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649610
JaLCDOI 10.18926/AMO/61428
フルテキストURL 75_1_9.pdf
著者 Gobara, Hideo| Yamamoto, Akira| Komakic, Toshiyuki| Kitayama, Toshiaki| Sakurai, Jun| Iguchi, Toshihiro| Matsui, Yusuke| Uka, Mayu| Tomita, Koji| Hiraki, Takao| Kanazawa, Susumu|
抄録 To assess the feasibility of needle tract ablation in liver tissue in ex vivo and in vivo animal models using a cryo-probe and electrosurgical device. The experimental device is made by inserting a cryoprobe through an intro-ducer sheath for insulation, with 2-cm of probe tip projecting out. A beagle liver was punctured by the device, and electric current was applied at 30-W with the electrosurgical knife touching the non-insulated device base. The discolored area of cut surface along the device was evaluated in 5 application-time groups (5 , 10 , 15 , 20, or 25 seconds). An ex vivo experiment was performed to determine an ablation algorithm with an appropriate application time by comparison with radiofrequency ablation (RFA) results. Thereafter, an in vivo experiment was performed to verify the algorithm’s feasibility. In the ex vivo model, the cut surface demonstrated different amounts of discolored area according to the application time. The total discolored area in the 20-seconds group was similar to that by RFA. In the in vivo model, the liver did not bleed, the total discolored area was similar to that ex vivo, and coagulation necrosis was confirmed by photomicrograph. Needle tract ablation can be per-formed using the experimental device and electrosurgical device.
キーワード needle tract ablation cryoablation electrosurgical device animal liver
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 9
終了ページ 14
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649608
フルテキストURL fulltext.pdf Fig_1.pptx Fig_2.pptx
著者 Maruyama, Yuki| Araki, Motoo| Wada, Koichiro| Yoshinaga, Kasumi| Mitsui, Yosuke| Sadahira, Takuya| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Yasuyuki| Watanabe, Masami| Watanabe, Toyohiko| Monga, Manoj| Nasu, Yasutomo| Kumon, Hiromi|
キーワード urothelial carcinoma urinary tract cancer ureteroscopy long-term survival renal pelvis ureter
備考 This is a pre-copyedited, author-produced version of an article accepted for publication in Japanese Journal of Clinical Oncology following peer review. The version of record Long-term ureteroscopic management of upper tract urothelial carcinoma: 28-year single-centre experience, Japanese Journal of Clinical Oncology, Volume 51, Issue 1, January 2021, Pages 130–137 is available online at: https://doi.org/10.1093/jjco/hyaa132.|
発行日 2020-7-27
出版物タイトル Japanese Journal of Clinical Oncology
51巻
1号
出版者 Oxford University Press
開始ページ 130
終了ページ 137
ISSN 0368-2811
NCID AA00690866
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
PubMed ID 32715306
DOI 10.1093/jjco/hyaa132
Web of Science KeyUT 000608420900018
関連URL isVersionOf https://doi.org/10.1093/jjco/hyaa132
JaLCDOI 10.18926/AMO/61424
フルテキストURL 75_1_1.pdf
著者 Hamahara, Jun| Honda, Hiroyuki| Yamamoto, Koichiro| Tokumasu, Kazuki| Hanayama, Yoshihisa| Hagiya, Hideharu| Obika, Mikako| Ueda, Keigo| Kishida, Masayuki| Otsuka, Fumio|
抄録 To determine the clinical characteristics of low androgen status in adult males with diabetes, we retrospectively analyzed the medical records of patients with type 2 diabetes mellitus in whom serum free testosterone (FT) levels were examined for 1 year. Among the 46 patients (56 ± 1.5 years old), decreases in serum FT levels to < 8.5 pg/ml (indicating the occurrence of late-onset hypogonadism [LOH]) were detected in 18 (39%). The per-centages of patients with low FT levels were high in the ≥ 50 years age group (83%), the HbA1c < 7% group (67%), and the 25 ≤ BMI < 30 kg/m2 group (56%). The serum FT levels tended to decrease age-dependently. The level of HbA1c was significantly correlated with the Heinemann Aging Male Symptoms (AMS) score (R = 0.47). The low-FT group had decreased levels of hemoglobin. Of note, the serum FSH level (R = −0.32) was negatively correlated with the serum FT level, whereas the serum TSH level (R = 0.36) was positively correlated with the serum FT level. Collectively, these results revealed that many diabetic males may have low FT levels and that the AMS score is related to the HbA1c level. A slightly anemic condition, thyroid dysfunction, and obesity (class 1) might be involved in LOH in middle-aged diabetic males.
キーワード androgen diabetes mellitus late-onset hypogonadism testosterone thyroid function
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-02
75巻
1号
出版者 Okayama University Medical School
開始ページ 1
終了ページ 8
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 33649607
フルテキストURL fulltext.pdf
著者 Muzembo, Basilua Andre| Ntontolo, Ngangu Patrick| Ngatu, Nlandu Roger| Khatiwada, Januka| Ngombe, Kabamba Leon| Numbi, Oscar Luboya| Nzaji, Kabamba Michel| Maotela, Kabinda Jeff| Ngoyi, Mukonkole Jean| Suzuki, Tomoko| Wada, Koji| Ikeda, Shunya|
発行日 2021-10-22
出版物タイトル PLoS ONE
15巻
10号
出版者 Public Library of Science
開始ページ e0241120
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 Muzembo et al.
論文のバージョン publisher
PubMed ID 33091054
DOI 10.1371/journal.pone.0241120
Web of Science KeyUT 000586647200003
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0241120
フルテキストURL fulltext.pdf
著者 Okada, Tomoaki| Miyoshi, Toru| Doi, Masayuki| Seiyama, Kosuke| Takagi, Wataru| Sogo, Masahiro| Nosaka, Kazumasa| Takahashi, Masahiko| Okawa, Keisuke| Ito, Hiroshi|
キーワード atherosclerotic cardiovascular disease polyunsaturated fatty acids eicosapentaenoic acid docosahexaenoic acid arachidonic acid descriptive study
発行日 2021-01-17
出版物タイトル Nutrients
13巻
1号
出版者 MDPI
開始ページ 253
ISSN 2072-6643
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 by the authors.
論文のバージョン publisher
PubMed ID 33477264
DOI 10.3390/nu13010253
Web of Science KeyUT 000610647500001
関連URL isVersionOf https://doi.org/10.3390/nu13010253
フルテキストURL 2021 02 sogawa cells tumoroid drug resist.pdf
著者 Sogawa, Chiharu| Eguchi, Takanori| Namba, Yuri| Okusha, Yuka| Aoyama, Eriko| Ohyama, Kazumi| Okamoto, Kuniaki|
キーワード gel-free 3D culture tumoroid cisplatin resistance imatinib (gleevec) tyrosine kinase inhibitor (TKI) spheroid metastatic colorectal cancer (mCRC) stem cells
発行日 2021-02-06
出版物タイトル Cells
10巻
2号
出版者 MDPI
開始ページ 344
ISSN 2073-4409
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2021 Authors.
論文のバージョン publisher
DOI 10.3390/cells10020344
関連URL isVersionOf https://doi.org/10.3390/cells10020344
フルテキストURL fulltext.pdf
著者 Noda, Hiroshi| Kimura, Shuhei| Hosokawa Morizane, Mio| Shiode, Yusuke| Doi, Shinichiro| Takahashi, Kosuke| Matoba, Ryo| Kanzaki, Yuki| Fujiwara, Atsushi| Morizane, Yuki|
発行日 2020-12-09
出版物タイトル Scientific Reports
10巻
1号
出版者 Nature Research
開始ページ 21497
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2020
論文のバージョン publisher
PubMed ID 33299123
DOI 10.1038/s41598-020-78693-5
Web of Science KeyUT 000608953600006
関連URL isVersionOf https://doi.org/10.1038/s41598-020-78693-5
フルテキストURL fulltext.pdf
著者 Miki, Tomoko| Yokota, Osamu| Haraguchi, Takashi| Ishizu, Hideki| Hasegawa, Masato| Ishihara, Takeshi| Ueno, Shu‐ichi| Takenoshita, Shintaro| Terada, Seishi| Yamada, Norihito|
キーワード aging‐related tau astrogliopathy argyrophilic grain granular/fuzzy astrocyte primary age‐related tauopathy tau tufted astrocyte
発行日 2020-04-15
出版物タイトル Brain Pathology
30巻
4号
出版者 Wiley
開始ページ 811
終了ページ 830
ISSN 1015-6305
NCID AA10776221
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 The Authors.
論文のバージョン publisher
PubMed ID 32293067
DOI 10.1111/bpa.12843
Web of Science KeyUT 000530564500001
関連URL isVersionOf https://doi.org/10.1111/bpa.12843
フルテキストURL K0006293_abstract_review.pdf K0006293_summary.pdf K0006293_fulltext.pdf
著者 野島 一郎|
発行日 2020-12-27
資料タイプ 学位論文
学位授与番号 甲第6293号
学位授与年月日 2020-12-27
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
フルテキストURL K0006291_abstract_review.pdf K0006291_summary.pdf K0006291_fulltext.pdf
著者 河原 明奈|
発行日 2020-12-27
資料タイプ 学位論文
学位授与番号 甲第6291号
学位授与年月日 2020-12-27
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
フルテキストURL fulltext.pdf
著者 Yamamoto, Akira| Fujii, Nobuharu| Obika, Mikako| Yamashita, Taro| Otsuka, Fumio|
キーワード localized AL amyloidosis ymphadenopathy PET-CT systemic AL amyloidosis
発行日 2020-10-01
出版物タイトル Internal Medicine
59巻
19号
出版者 The Japanese Society of Internal Medicine
開始ページ 2415
終了ページ 2418
ISSN 1349-7235
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2020 by The Japanese Society of Internal Medicine
論文のバージョン publisher
PubMed ID 32611959
DOI 10.2169/internalmedicine.4651-20
関連URL isVersionOf https://doi.org/10.2169/internalmedicine.4651-20
フルテキストURL fulltext.pdf
著者 Kimura, Jun| Ohkubo, Takahiro| Nishina, Yuta| Urita, Koki| Kuroda, Yasushige|
発行日 2021-01-04
出版物タイトル RSC Advances
11巻
2号
出版者 Royal Society of Chemistry
開始ページ 838
終了ページ 846
ISSN 2046-2069
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン publisher
DOI 10.1039/D0RA08437A
Web of Science KeyUT 000607364700023
関連URL isVersionOf https://doi.org/10.1039/D0RA08437A
フルテキストURL fulltext.pdf
著者 Toh, Norihisa| Kotani, Yasuhiro| Akagi, Teiji| Kuroko, Yosuke| Baba, Kenji| Otsuki, Shin-ichi| Kasahara, Shingo| Ito, Hiroshi|
キーワード Pulmonary atresia with intact ventricular septum adult congenital heart disease outcome
発行日 2020-06-17
出版物タイトル Congenital Heart Disease
15巻
1号
出版者 Wiley
開始ページ 1
終了ページ 11
ISSN 1747-079X
NCID AA12157082
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン publisher
DOI 10.32604/CHD.2020.011579
Web of Science KeyUT 000564363500001
関連URL isVersionOf https://doi.org/10.32604/CHD.2020.011579
フルテキストURL fulltext.pdf
著者 Akiba, Kazuto| Iwamoto, Kaisei| Sato, Takaaki| Araki, Shingo| Kobayashi, Tatsuo C.|
発行日 2020-10-16
出版物タイトル Physical Review Research
2巻
4号
出版者 American Physical Society
開始ページ 043090
ISSN 2643-1564
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Authors.
論文のバージョン publisher
DOI 10.1103/PhysRevResearch.2.043090
Web of Science KeyUT 000605396700005
関連URL isVersionOf https://doi.org/10.1103/PhysRevResearch.2.043090
フルテキストURL fulltext.pdf
著者 Kojima, Keiichi| Yoshizawa, Susumu| Hasegawa, Masumi| Nakama, Masaki| Kurihara, Marie| Kikukawa, Takashi| Sudo, Yuki|
発行日 2020-11-30
出版物タイトル Scientific Reports
10巻
1号
出版者 Nature Research
開始ページ 20857
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2020
論文のバージョン publisher
PubMed ID 33257762
DOI 10.1038/s41598-020-77936-9
Web of Science KeyUT 000609202800018
関連URL isVersionOf https://doi.org/10.1038/s41598-020-77936-9