検索結果 47819 件
著者 | 山本 祐司| |
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発行日 | 2011-08-01 |
出版物タイトル | 岡山医学会雑誌 |
巻 | 123巻 |
号 | 2号 |
資料タイプ | 一般雑誌記事 |
著者 | 松田 忠和| |
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発行日 | 2011-08-01 |
出版物タイトル | 岡山医学会雑誌 |
巻 | 123巻 |
号 | 2号 |
資料タイプ | 一般雑誌記事 |
著者 | Yanagi, Yoshinobu| Fujita, Mariko| Hisatomi, Miki| Matsuzaki, Hidenobu| Konouchi, Hironobu| Katase, Naoki| Nagatsuka, Hitoshi| Asaumi, Jun-ichi| |
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発行日 | 201012 |
出版物タイトル | Oral Radiology |
巻 | 26巻 |
号 | 2号 |
資料タイプ | 学術雑誌論文 |
著者 | 岡山大学法学会| |
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発行日 | 2011-08-25 |
出版物タイトル | 岡山大學法學會雜誌 |
巻 | 61巻 |
号 | 1号 |
資料タイプ | その他 |
著者 | 岡山大学法学会| |
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発行日 | 2011-08-25 |
出版物タイトル | 岡山大學法學會雜誌 |
巻 | 61巻 |
号 | 1号 |
資料タイプ | その他 |
著者 | 趙 炳宣| |
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発行日 | 2011-08-25 |
出版物タイトル | 岡山大學法學會雜誌 |
巻 | 61巻 |
号 | 1号 |
資料タイプ | 一般雑誌記事 |
タイトル(別表記) | Eugen Ehrlich, Bismarck und der Weltkrieg |
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フルテキストURL | olj_061_1_133_156.pdf |
著者 | 平田 公夫| |
出版物タイトル | 岡山大學法學會雜誌 |
発行日 | 2011-08-25 |
巻 | 61巻 |
号 | 1号 |
開始ページ | 133 |
終了ページ | 156 |
ISSN | 0386-3050 |
言語 | 日本語 |
論文のバージョン | publisher |
NAID | 120003290185 |
タイトル(別表記) | L’assistance publique en France pendant la Révolution sous la Convention (2) |
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フルテキストURL | olj_061_1_093_131.pdf |
著者 | 波多野 敏| |
出版物タイトル | 岡山大學法學會雜誌 |
発行日 | 2011-08-25 |
巻 | 61巻 |
号 | 1号 |
開始ページ | 93 |
終了ページ | 131 |
ISSN | 0386-3050 |
言語 | 日本語 |
論文のバージョン | publisher |
NAID | 40018973677 |
タイトル(別表記) | A Study on Law-Related Education (2) |
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フルテキストURL | olj_061_1_077_092.pdf |
著者 | 辻 博明| |
出版物タイトル | 岡山大學法學會雜誌 |
発行日 | 2011-08-25 |
巻 | 61巻 |
号 | 1号 |
開始ページ | 77 |
終了ページ | 92 |
ISSN | 0386-3050 |
言語 | 日本語 |
論文のバージョン | publisher |
NAID | 40018973676 |
タイトル(別表記) | Regelung der Schadensschätzung |
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フルテキストURL | olj_061_1_037_075.pdf |
著者 | 伊東 俊明| |
出版物タイトル | 岡山大學法學會雜誌 |
発行日 | 2011-08-25 |
巻 | 61巻 |
号 | 1号 |
開始ページ | 37 |
終了ページ | 75 |
ISSN | 0386-3050 |
言語 | 日本語 |
論文のバージョン | publisher |
NAID | 40018973675 |
タイトル(別表記) | A Study on Surrender of Security by Creditor : Historical and Comparative Perspectives (1) |
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フルテキストURL | olj_061_1_023_036.pdf |
著者 | 辻 博明| |
出版物タイトル | 岡山大學法學會雜誌 |
発行日 | 2011-08-25 |
巻 | 61巻 |
号 | 1号 |
開始ページ | 23 |
終了ページ | 36 |
ISSN | 0386-3050 |
言語 | 日本語 |
論文のバージョン | publisher |
NAID | 40018973674 |
タイトル(別表記) | Right to Obtain Reimbursement among Jointly and Severally Liable Guarantors |
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フルテキストURL | olj_061_1_001_022.pdf |
著者 | 吉岡 伸一| |
出版物タイトル | 岡山大學法學會雜誌 |
発行日 | 2011-08-25 |
巻 | 61巻 |
号 | 1号 |
開始ページ | 1 |
終了ページ | 22 |
ISSN | 0386-3050 |
言語 | 日本語 |
論文のバージョン | publisher |
NAID | 40018973673 |
著者 | 岡山大学法学会| |
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発行日 | 2011-08-25 |
出版物タイトル | 岡山大學法學會雜誌 |
巻 | 61巻 |
号 | 1号 |
資料タイプ | その他 |
JaLCDOI | 10.18926/AMO/46853 |
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フルテキストURL | 65_4_269.pdf |
著者 | Hidaka, Noriaki| Suemaru, Katsuya| Takechi, Kenshi| Li, Bingjin| Araki, Hiroaki| |
抄録 | We previously showed that inhibition of repeated electroconvulsive shock (ECS)-induced seizures through 7-day administration of anti-epileptic drugs suppressed the impairment of spontaneous alternation behavior in the Y-maze test in rats. To clarify the precise mechanism(s), we investigated the effect of valproate on such impairment and examined the levels of brain-derived neurotrophic factor (BDNF) and c-Fos protein in the prefrontal cortex and the hippocampus 24h after the last administration of ECS. Seven-day intraperitoneal (i.p.) administration of valproate (400mg/kg) suppressed the impairment of spontaneous alternation behavior. Repeated ECS increased the BDNF protein levels in the hippocampus and prefrontal cortex in the presence or absence of valproate, indicating that the increase in BDNF protein levels resulted from electrical stimulation. c-Fos protein levels were significantly decreased in the hippocampal dentate gyrus after repeated ECS, but valproate had no significant effect on decreased c-Fos protein levels. Valproate+ECS significantly increased the c-Fos protein levels of the prefrontal cortex compared with the ECS group. These findings suggest that the inhibitory effect of valproate on repeated ECS-induced impairment of spontaneous alternation behavior may be linked to the prefrontal cortex. |
キーワード | electroconvulsive shock-induced seizure spontaneous alternation behavior valproate brain-derived neurotrophic factor c-Fos |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2011-08 |
巻 | 65巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 269 |
終了ページ | 277 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 21860534 |
Web of Science KeyUT | 000294236700008 |
JaLCDOI | 10.18926/AMO/46852 |
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フルテキストURL | 65_4_265.pdf |
著者 | Kojima, Katsuhide| Kato, Katsuya| Oto, Takahiro| Mitsuhashi, Toshiharu| Shinya, Takayoshi| Sei, Tetsuro| Okumura, Yoshihiro| Sato, Shuhei| Miyoshi, Shinichiro| Kanazawa, Susumu| |
抄録 | To determine the effectiveness of living-donor lobar lung transplantation (LDLLT), it is necessary to predict the recipient's postoperative lung function. Traditionally, Date's formula, also called the segmental ratio, has used the number of lung segments to estimate the forced vital capacity (FVC) of grafts in LDLLT. To provide a more precise estimate of graft FVC, we calculated the volumes of the lower lobe and total lung using three-dimensional computed tomography (3D-CT) and the volume ratio between them. We calculated the volume ratio in 52 donors and tested the difference between the segmental volume ratios with a one-tailed t-test. We also calculated the predicted graft FVC in 21 LDLLTs using the segmental ratio pFVC(c) and the volume ratio pFVC(v), and then found the Pearson's correlation coefficients for both pFVC(c) and pFVC(v) with the recipients' actual FVC (rFVC) measured spirometrically 6 months after surgery. Significant differences were found between the segmental ratio and the average volume ratio for both sides (right, p=0.03;left, p=0.0003). Both pFVC(c) and pFVC(v) correlated significantly with rFVC at 6 months after surgery (p=0.007 and 0.006). Both the conventional and the volumetric methods provided FVC predictions that correlated significantly with measured postoperative FVC. |
キーワード | living-donor lobar lung transplantation 3D-CT volumetry |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2011-08 |
巻 | 65巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 265 |
終了ページ | 268 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 21860533 |
Web of Science KeyUT | 000294236700007 |
JaLCDOI | 10.18926/AMO/46851 |
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フルテキストURL | 65_4_259.pdf |
著者 | Ogata, Yoshiko| Aoe, Keisuke| Hiraki, Akio| Murakami, Kazuo| Kishino, Daizo| Chikamori, Kenichi| Maeda, Tadashi| Ueoka, Hiroshi| Kiura, Katsuyuki| Tanimoto, Mitsune| |
抄録 | The objective of this study was to evaluate the utility of the determination of adenosine deaminase (ADA) level in pleural fluid for the differential diagnosis between tuberculous pleural effusion (TPE) and malignant pleural effusion (MPE) in Japan, a country with intermediate incidence of tuberculosis (TB). We retrospectively reviewed the clinical records of 435 patients with pleural effusion and investigated their pleural ADA levels as determined by an auto analyzer. ROC analysis was also performed. The study included patients with MPE (n=188), TPE (n=124), benign nontuberculous pleural effusion (n=94), and pleural effusion of unknown etiology (n=29). The median ADA level in the TPE group was 70.8U/L, which was significantly higher than that in any other groups (p<0.05). The area under the curve (AUC) in ROC analysis was 0.895. With a cut-off level for ADA of 36U/L, the sensitivity, specificity, positive predictive value, and negative predictive value were 85.5%, 86.5%, 69.7%, and 93.6%, respectively. As many as 9% of patients with lung cancer and 15% of those with mesothelioma were false-positive with this ADA cutoff setting. Although the ADA activity in pleural fluid can help in the diagnosis of TPE, it should be noted that some cases of lung cancer or mesothelioma show high ADA activity in geographical regions with intermediate incidence of TB, in contrast to high prevalence areas. |
キーワード | pleural effusion adenosine deaminase tuberculosis lung cancer mesothelioma |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2011-08 |
巻 | 65巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 259 |
終了ページ | 263 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 21860532 |
Web of Science KeyUT | 000294236700006 |
JaLCDOI | 10.18926/AMO/46850 |
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フルテキストURL | 65_4_247.pdf |
著者 | Watanabe, Naomi| Shikata, Kenichi| Shikata, Yasushi| Sarai, Kei| Omori, Kazuyoshi| Kodera, Ryo| Sato, Chikage| Wada, Jun| Makino, Hirofumi| |
抄録 | Inflammatory processes are involved in the pathogenesis of diabetic nephropathy. The aim of this study was to clarify the role of mitogen-activated protein kinase (MAPK) pathways for induction of intercellular adhesion molecule-1 (ICAM-1) expression in glomerular endothelial cells under diabetic conditions. We examined the expression of ICAM-1 in the kidneys of experimental diabetic rats. Human glomerular endothelial cells (GE cells) were exposed to normal glucose concentration, high glucose concentration (HG), or high mannitol concentration (HM), and then the expression of the ICAM-1 protein and the phosphorylation of the 3 subfamilies of mitogen-activated protein kinase (MAPK) were determined using Western blot analysis. Next, to evaluate the involvement of MAPKs in HG- or HM-induced ICAM-1 expression, we preincubated GE cells with the inhibitors for ERK, p38 or JNK 1h prior to the application of glucose or mannitol. Expression of ICAM-1 was increased in the glomeruli of diabetic rats. Both HG and HM induced ICAM-1 expression and phosphorylation of ERK1/2, p38 and JNK in GE cells. Expression of ICAM-1 was significantly attenuated by inhibitors of ERK, p38 and JNK. We conclude that activation of ERK1/2, p38 and JNK cascades may be involved in ICAM-1 expression in glomerular endothelial cells under diabetic conditions. |
キーワード | diabetic nephropathy ICAM-1 ERK p38 MAPK JNK |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2011-08 |
巻 | 65巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 247 |
終了ページ | 257 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 21860531 |
Web of Science KeyUT | 000294236700005 |
JaLCDOI | 10.18926/AMO/46849 |
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フルテキストURL | 65_4_239.pdf |
著者 | Cho, Yong-Pil| Kwon, Tae-Won| Kwon, Sun U.| Chae, Won-Young| Kim, Geun-Eun| |
抄録 | We described 9 consecutive patients who underwent operative carotid artery exploration with attempted carotid endarterectomy (CEA) for symptomatic internal carotid artery (ICA) occlusion. Indications for this surgery based on vascular imaging included segmental occlusion of the proximal ICA and also extensive occlusion of the distal ICA in selected patients in whom color-flow duplex ultrasound showed a poorly echogenic or anechoic thrombus with a flow void, suggestive of an acute thrombus. CEA was performed successfully to restore blood flow in all 9 patients:CEA in 5 and CEA with Fogarty thrombectomy in 4. Postoperative magnetic resonance (MR) angiography confirmed that revascularization had been successful in all 9 patients, and MR imaging displayed improved perfusion in 4 patients. Despite the lack of a generalized efficacy of surgical revascularization for symptomatic ICA occlusion, our study demonstrated that preoperative vascular imaging allows the selection of patients who may benefit from CEA. |
キーワード | internal carotid artery occlusion carotid endarterectomy vascular imaging |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2011-08 |
巻 | 65巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 239 |
終了ページ | 245 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 21860530 |
Web of Science KeyUT | 000294236700004 |
JaLCDOI | 10.18926/AMO/46848 |
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フルテキストURL | 65_4_231.pdf |
著者 | Shien, Tadahiko| Doihara, Hiroyoshi| Nishiyama, Keiko| Masuda, Hiroko| Nogami, Tomohiro| Ikeda, Hirokuni| Taira, Naruto| |
抄録 | Combined low-dose therapy of oral capecitabine (Xeloda) and cyclophosphamide (XC) has been demonstrated to be useful for long-term control of lesions in patients with metastatic breast cancer (MBC) and is aimed at symptomatic alleviation and prolongation of survival. Here, a retrospective review was conducted of MBC patients administered XC at the Okayama University Hospital (OUH), to evaluate responses to XC, adverse events and time to progression (TTP). Twenty patients with MBC received XC between 2006 and 2009. With the exception of 2 elderly patients who were over the age of 70 at the initial examination, all of the patients had received prior treatment with an anthracycline and/or a taxane. No complete response (CR) cases were observed, but partial response (PR) was achieved in 6 patients (30%) and SD in 9 (45%), of whom 5 (20%) sustained SD status for >12 months. The median TTP was 6 months (range:3-27 mo.). Three patients developed Grade 3 adverse events (diarrhea, nausea and stomatitis), but no other patients developed adverse reactions causing interruption of the therapy. XC was safe even in previously treated and elderly MBC patients;moreover, it yielded remarkable clinical responses. |
キーワード | metastatic breast cancer metronomic chemotherapy |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2011-08 |
巻 | 65巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 231 |
終了ページ | 237 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 21860529 |
Web of Science KeyUT | 000294236700003 |
JaLCDOI | 10.18926/AMO/46847 |
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フルテキストURL | 65_4_225.pdf |
著者 | Miura, Masanobu| Naka, Toru| Miyaishi, Satoru| |
抄録 | Postmortem changes in myoglobin concentrations in blood and organs were investigated using an enzyme immunoassay by animal experiments in combination with immunohistochemical staining of human cases. Blood myoglobin concentrations were found to increase drastically within a very short time after death. Those in striated muscle, however, did not change by day 14 postmortem. Myoglobin content in the liver and kidney increased slightly by day 5 postmortem, and more obviously by day 7 or later. However, almost no change was observed by day 5 in the kidney when the renal artery and vein had been ligated just after death. In the thyroid gland and the lung, the myoglobin content markedly increased by day 7 postmortem, with the logarithmical values rising nearly linearly as the time after death passed. In the thyroid gland, concentrations reached the level of the striated muscle. The mechanisms of postmortem myoglobin increase in organs are thought to be direct diffusion from the striated muscle and/or distribution through the blood. To estimate the postmortem interval, the determination of myoglobin content in the thyroid gland or the lung appears to be useful. |
キーワード | myoglobin postmortem diffusion postmortem distribution postmortem interval |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2011-08 |
巻 | 65巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 225 |
終了ページ | 230 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 21860528 |
Web of Science KeyUT | 000294236700002 |