検索結果 35 件
| フルテキストURL | K0004656.pdf K0004656_honbun.pdf |
|---|---|
| 著者 | 近末 久美子| |
| 発行日 | 2012-09-27 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第4656号 |
| 学位授与年月日 | 2012-09-27 |
| 学位・専攻分野 | 博士（保健学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 英語 |
| 著者 | 坂下 昇| |
|---|---|
| 発行日 | 1957-03-31 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 69巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 目黒 忠道| 緒方 正名| |
|---|---|
| 発行日 | 1989-02 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 101巻 |
| 号 | 1-2号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 石川 治| |
|---|---|
| 発行日 | 1990-08 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 102巻 |
| 号 | 7-8号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/21168 |
|---|---|
| タイトル（別表記） | Excretion of radon in expired air after bathing and drinking of radioactive hot spring water at Misasa Spa |
| フルテキストURL | 049_001_006.pdf |
| 著者 | 古野 勝志| |
| 抄録 | Radon (Rn) contents in expired air after bathing, exposure in hot-air room and drinking of Misasa radioactive hot spring water were determined using an ionization chamber equiped with vibrating reed electrometer. The results were as follows; 1. Rn Contents in the indoor and outdoor air of Misasa spa were in the range of 0.5-1.0 pCi/ℓ and 0.4-0.7 pCi/ℓ. 2. Rn contents in the expired air of persons living at Misasa spa area and none spa area were 0.4-0.9 pCi/ℓ, 0.6±0.2 (S.D.) pCi/ℓ and 0.1-0.9 pCi/ℓ, 0.5±0.2 (S.D.) pCi/ℓ respectively and no difference of Rn contents was observed in both groups. 3. The highest Rn contents in the expired air of subjects bathed in radioactive hot spring (Rn ; 58.0×10(-10) Ci/kg, watre temp. : 41±1℃.) were immediately after bathing, and the values were 10.8-25.5 pCi/ℓ (bathing for 5 min.), 16.0-27.9 pCi/ℓ (bathing for 10 min.) and 38.8-59.3 pCi/ℓ (bathing for 15 min.) respectively. Rn contents in expired air were reduced to about 1.0 pCi/ℓ during 120-180 min. after bathing. The longer the bathing time and the younger the subjects, the higher Rn contents in the expired air. The biological half-life of Rn in the expired air of subjects after bathing was 42-43 min. 4. The highest Rn contents in the expired air of subjects exposed in hot-air room (Rn in air; 54.3pCi/ℓ, air temp. : 37-38℃., humidity: 40%, staying for 15 min.), and the values were 4.9-7.8 pCi/ℓ, and gradually reduced to about 1.0 pCi/ℓ during 120 min. The bioligical half-life of Rn in the expired air after leaving the hot-air room was 43 min. 5. Rn contents in the expired air of subjects immediately after drinking of radioactive spring water (Rn contents: 596.8×10(-10) Ci/kg, 500mℓ), were the highest, and the value were 28.0-101.5 pCi/ℓ, and reduced to about 1.0pCi/ℓ during 180 min. after drinking. The biological half-life of Rn in the expired air was 40 min. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1979-09-25 |
| 巻 | 49巻 |
| 開始ページ | 1 |
| 終了ページ | 6 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40000321143 |
| 著者 | 杉原 黎子| |
|---|---|
| 発行日 | 1979-10-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 91巻 |
| 号 | 9-10号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 目黒 忠道| 坪田 信孝| 実成 文彦| 西岡 慶子| 緒方 正名| |
|---|---|
| 発行日 | 1979-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 91巻 |
| 号 | 5-6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 劒持 堅志| |
|---|---|
| 発行日 | 1984-04-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 96巻 |
| 号 | 5-6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 高原 和夫| |
|---|---|
| 発行日 | 1986-12-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 98巻 |
| 号 | 11-12号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 愛甲 博美| |
|---|---|
| 発行日 | 1988 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 100巻 |
| 号 | 11-12号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 神谷 次郎| |
|---|---|
| 発行日 | 1987-12-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 99巻 |
| 号 | 11-12号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 神谷 次郎| |
|---|---|
| 発行日 | 1987-12-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 99巻 |
| 号 | 11-12号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 坂野 成宏| |
|---|---|
| 発行日 | 1987-08-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 99巻 |
| 号 | 7-8号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/14905 |
|---|---|
| タイトル（別表記） | 胸部高分解能CT（HRCT）による肺野low attenuation area（LAA）の定量的評価 ―気管支喘息および肺気腫症例の比較検討― |
| フルテキストURL | 071_019_028.pdf |
| 著者 | 光延 文裕| 御舩 尚志| 芦田 耕三| 保﨑 泰弘| 柘野 浩史| 岡本 誠| 原田 誠之| 中井 睦郎| 谷崎 勝朗| |
| 抄録 | Background: Assessment of low attenuation areas and lung densitometry on high resolution computed tomography (HRCT) have been reported in studies of patients with chronic obstructive pulmonary disease. Objective : The purpose of this study was to examine if HRCT could separate asthmatic patients from normal control subjects and patients with emphysema. Methods : Subjects were divided into three groups : 24 patients with bronchial asthma, 23 patients with pulmonary emphysema and 15 normal controls. HRCT scans of the lung were performed at three different levels at both end inspiration and expiration in all patients and control subjects. Results : The mean CT number of three slices was significantly lower in asthmatic subjects compared with normal individuals at both end inspiration (p < 0.05) and expiration (p < 0.01). The relative area of the lung with an attenuation value lower than -950 HU (% LAA) for three slices was significantly higher in asthmatic subjects than in normal individuals at end inspiration (p < 0.05), but there was no significant difference at end expiration. The mean CT number and % LAA obtained from studies that were performed at three cm above the top of the diaphragm provided the best separation among three anatomic levels. In comparison between asthmatic and emphysema patients, both parameters were significantly different in asthmatic subjects than in those with emphysema at both end inspiration and expiration on each scan and in the total scans (p < 0.001). Conclusions : HRCT is a useful method to separate asthmatic subjects from patients with emphysema and normal subjects. |
| キーワード | HRCT asthma emphysema |
| 出版物タイトル | 岡大三朝分院研究報告 |
| 発行日 | 2001-02-01 |
| 巻 | 71巻 |
| 開始ページ | 19 |
| 終了ページ | 28 |
| ISSN | 0918-7839 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308115 |
| JaLCDOI | 10.18926/14788 |
|---|---|
| タイトル（別表記） | 肺気腫と喘息のHRCT上のlow attenuation are（LAA）の性質の差。喫煙との関連を含めて |
| フルテキストURL | 74_035_041.pdf |
| 著者 | 光廷 文裕| 保崎 泰弘| 芦田 耕三| 岩垣 尚史| 永田 拓也| 藤井 誠| 高田 真吾| 横井 正| 浜田 全紀| 谷崎 勝朗| |
| 抄録 | The low attenuation area (LAA) of the lungs on high resolution computed tomography (HRCT) was evaluated in 20 asthmatics (10 ex-smokers and 10 never-smokers) and 10 patients with pulmonary emphysema (all ex-smokers) by ventilatory function, lung volume, DLco, and a ratio of expiratory LAA/inspiratory LAA. 1 . The % LAA of the lungs on HRCT was significantly larger in patients with pulmonary emphysema(PE) than in those with asthma, but there was not significant difference in % LAA between ex-smokers and never-smokers of asthmatics. 2. A ratio of expiratory Winspiratory LAA was significantly higher in patients with PE than in those with asthma , and the ratio was significantly higher in ex-smokers of asthmatics than in never-smokers (p<0.05). 3 . The difference in % residual volume and % DLco was significant between asthma and PE , and between ex - smokers and never-smokers of asthmatics (% RV : p<0.05, DLco : p<0.05) . 4 . The difference in the values of % FVC, % FEV(1) .O, and FEV1.0% was significant between asthma and PE, but not significant between ex-smokers and never- smokers of asthmatics. The results suggest that the difference in a ratio of expiratory W inspiratory LAA, % RV and % DLco was significant between ex - smokers and never - smokers of asthmatics , and cigarette smoking induces more irreversible changes of the lungs. |
| キーワード | low attenuation area asthma pulmonary emphysema cigarette smoking |
| 出版物タイトル | 岡大三朝医療センター研究報告 |
| 発行日 | 2004-02-01 |
| 巻 | 74巻 |
| 開始ページ | 35 |
| 終了ページ | 41 |
| ISSN | 1348-1258 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002308507 |
| JaLCDOI | 10.18926/14764 |
|---|---|
| タイトル（別表記） | lgEにmediatedされるアレルギ反応― 、肺機能、HRCT上の肺のlow attenuatjonarea (LAA)、およびLTB4,LTC4産生から見た喘息の病態に対する加齢の影響 |
| フルテキストURL | 73_031_038.pdf |
| 著者 | 光延 文裕| 芦田 耕三| 保崎 泰弘| 柘野 浩史| 西田 典数| 永田 拓也| 横井 正| 高田 真吾| 谷崎 勝朗| |
| 抄録 | The influence of aging on the pathophysiology of asthma in the elderly was examined in 40 patients (20 younger asthmatics under the age of 50 years, mean age 32.5 years and 20 elderly asthmatics over the age of 70 years, mean age 74.3 years), relating to IgE - mediated allergy, pulmonary function, low attenuation area (LAA) of the lungs on HRCT, and the generation of leukotrienes B4 (LTB4) and C4 (LTC4) by leukocytes. The frequency of patients with serum IgE of more than 200 IU/ml, and the incidence of those with a positive RAST score for inhalant allergens were significantly higher in younger patients than in elderly subjects. The values of % FVC, % FEV1 and FEV 1% were significantly larger in younger patients compared with elderly subjects. The % RV was significantly larger in elderly patients than in younger patients, however, the difference in % DLco was not significant between the two age groups. The LAA of the lungs on HRCT and the ratio of expiratory LAA (exp LAA) to inspiratory LAA (ins LAA) were also significantly larger in elderly asthmatics than in younger subjects. The generation of LTB4 and LTC4 was larger in younger patients than in elderly subjects, and LTB4 generation was significantly larger in younger subjects compared with elderly subjects. These results suggest that changes in IgE-mediated allergy, airflow and lung volume accompanied with hyperinflation are often observed in elderly asthmatics. |
| キーワード | IgE-mediated allergy pulmonary function elderly asthmatics HRCT % RV |
| 出版物タイトル | 岡大三朝医療センター研究報告 |
| 発行日 | 2003-02-01 |
| 巻 | 73巻 |
| 開始ページ | 31 |
| 終了ページ | 38 |
| ISSN | 1348-1258 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308601 |
| JaLCDOI | 10.18926/14753 |
|---|---|
| タイトル（別表記） | 高齢者喘息における HRCT 上の肺の low attenuation area (LAA) に及ぼす長期間喫煙の影響．肺気腫症例との比較． |
| フルテキストURL | 73_019_024.pdf |
| 著者 | 光延 文裕| 保﨑 泰弘| 芦田 耕三| 柘野 浩史| 西田 典数| 永田 拓也| 高田 真吾| 横井 正| 谷崎 勝朗| |
| 抄録 | The influence of cigarette smoking on the pathophysiology in elderly patients with asthma. Forty asthmatics over the age of 70 years (20 ex-smokers and 20 never-smokers), and 20 patients with pulmonary emphysema over age 70 (all ever-smokers) were studied to determine the influence of cigarette smoke on the low attenuation area (LAA) <-950 HU (RA950) of the lungs on high resolution CT (HRCT) scans, and the ratio of expiratory LAA to inspiratory LAA of the lungs in relation to pulmonary function. The LAA value was significantly higher in patients with pulmonary emphysema compared with ever-smokers of asthmatics. The LAA ratio was significantly higher in ever-smokers than in never-smokers of asthmatics, and the ratio was less than 0.5 in all never-smokers, and the ratio was more than 0.5 in 10 of 20 ever-smokers of asthmatics and in all patients with pulmonary emphysema. The % RV (residual volume) was significaltly larger and % DLco (diffusing capacity for carbon monoxide) was significantly lower in subjects with the ratio more than 0.5 than in those with the ratio less than 0.5. These results suggest that cigarette smoke influences LAA of the lungs in relation to % RV value and % DLco value. |
| キーワード | cigarette smoking high resolution CT % RV % DLco elderly asthmatics |
| 出版物タイトル | 岡大三朝医療センター研究報告 |
| 発行日 | 2003-02-01 |
| 巻 | 73巻 |
| 開始ページ | 19 |
| 終了ページ | 24 |
| ISSN | 1348-1258 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308216 |
| JaLCDOI | 10.18926/14750 |
|---|---|
| タイトル（別表記） | 気管支喘息の low attenuation are (LAA) に対する長期喫煙の影響-4年間の経過観察- |
| フルテキストURL | 73_010_018.pdf |
| 著者 | 光延 文裕| 芦田 耕三| 保﨑 泰弘| 柘野 浩史| 岡本 誠| 西田 典数| 永田 拓也| 高田 真吾| 横井 正| 中井 睦郎| 谷崎 勝朗| 谷本 光音| |
| 抄録 | Background-The influence of cigarette smoking on the pathogenesis of asthma in the elderly remains controversial. This study attempts to estimate longitudinal changes in HRCT (high resolution computed tomography) parameters and pulmonary function parameters obtained for ex-smokers and never-smokers in asthmatics during 4-yr follow-up period. Methods-Fourteen asthmatics (6 ex-smokers and 8 never-smokers) were studied to determine the influence of aging and cigarette smoking on pulmonary function, and mean lung density (MLD) and the relative area of the lung showing attenuation values less than -950 HU (RA950) on HRCT scans. Results-The values of FVC and FEV1, were significantly more decreased in asthmatics without a smoking history during 4-yr follow-up period. The values of FVC, FEV1, FEV1/FVC and DLco/VA were significantly decreased and RV/TLC were significantly increased in asthmatics with a smoking history over 4 years, and annual decline in FEV1 ex-smokers was larger than that in never-smokers. In the upper lung field, inspiratory MLD was observed to shift in a negative direction and inspiratory RA950 was found to increase during 4-yr observation period in ex-smokers, but not in never-smokers. In the middle lung field, inspiratory RA950 was significantly enhanced in both two groups. Although expiratory MLD, expiratory RA950 and exp RA950/ins RA950 were observed to change significantly during the observation period in ex-smokers, no changes were observed in never-smokers. Conclusion-These results suggest that aging augments airspace enlargement predominantly in the middle lung field, while long term cigarette smoking further worsens emphysematous alterations in the upper lung field. |
| キーワード | lung density high resolution computed tomography asthma |
| 出版物タイトル | 岡大三朝医療センター研究報告 |
| 発行日 | 2003-02-01 |
| 巻 | 73巻 |
| 開始ページ | 10 |
| 終了ページ | 18 |
| ISSN | 1348-1258 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308656 |
| 著者 | 藤澤 邦康| |
|---|---|
| 発行日 | 1990-02 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 102巻 |
| 号 | 1-2号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 廣田 直敷| |
|---|---|
| 発行日 | 1991 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 103巻 |
| 号 | 4号 |
| 資料タイプ | 学術雑誌論文 |