検索結果 1668 件
| JaLCDOI | 10.18926/AMO/66675 |
|---|---|
| フルテキストURL | 78_1_085.pdf |
| 著者 | Miyake, Keisuke| Tanikawa, Tomohiro| Haruma, Ken| Kawada, Mayuko| Ishii, Katsunori| Urata, Noriyo| Nishino, Ken| Suehiro, Mitsuhiko| Kawanaka, Miwa| Manabe, Noriaki| Kawamoto, Hirofumi| |
| 抄録 | A 30-year-old man with idiopathic peptic ulcer disease (IPUD) experienced repeated recurrence of ulcerative bleeding despite treatment with lansoprazole and then vonoprazan. Further evaluation suggested that the cause of the ulcer was strong contractile movements of the antrum. This prompted the co-administration of trimebutine maleate (TM) and vonoprazan to relieve the stomach contractions. TM was effective in preventing the recurrence of ulcerative bleeding, and the patient has remained in remission for 4 years. This case highlights the potential efficacy of TM in treating IPUD and the importance of considering hypercontractility as the underlying cause in cases of IPUD. |
| キーワード | gastric ulcer idiopathic peptic ulcerative disease trimebutine maleate |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 85 |
| 終了ページ | 88 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419319 |
| Web of Science KeyUT | 001204421300002 |
| JaLCDOI | 10.18926/AMO/66671 |
|---|---|
| フルテキストURL | 78_1_053.pdf |
| 著者 | Ichikawa, Yukiko| Ogino, Tetsuya| |
| 抄録 | Ice bags are frequently used in medical care settings for pain relief, comfort, and in some cases, whole-body cooling. This study quantifies heat energy transfer capacity of ice bags and evaluates their cooling effects on body temperature. Forty-eight healthy adults in their 20s were recruited. An ice bag wrapped in two layers of dry towel was applied to the forehead, neck, or palm of each participant for 10 min. The skin surface temperature, heat flow, and core temperature were recorded during the cooling and non-cooling periods, with energy transfer calculated by integrating heat flow over time. Over the non-cooling period, 31.4-53.6 kJ·m-2 of energy was dissipated over 10 min, whereas during the cooling period, the range increased to 180.0-218.7 kJ·m-2 over 10 min. Skin surface temperature decreased by 3.2-5.7°C, whereas core temperature was unchanged. Ice bag use augmented energy transfer by about 150-180 kJ·m-2 over 10 min, but this was insufficient for rapid whole body cooling due to the small skin-surface area in contact with the ice bag. The measured energy transfer indicated that topical ice bag application absorbs insufficient energy to affect core temperature. Quantitative assessment of energy transfer was shown to inform the safe and appropriate use of thermotherapy. |
| キーワード | cold compress fever hyperthermia thermal conductivity thermoregulation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 53 |
| 終了ページ | 61 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419315 |
| Web of Science KeyUT | 001203658200009 |
| JaLCDOI | 10.18926/AMO/66670 |
|---|---|
| フルテキストURL | 78_1_047.pdf |
| 著者 | Shimomura, Manabu| Shinozaki, Katsunori| Yano, Takuya| Akabane, Shintaro| Ohdan, Hideki| Hiroshima Surgical study group of Clinical Oncology (HiSCO)| |
| 抄録 | Oral fluoropyrimidines (FUs) have certain advantages over intravenous FUs, such as longer intervals between outpatient visits, no requirement for central venous port (CVP) implantation, and lower incidence of neutropenia. We previously reported the efficacy of S-1/oxaliplatin (SOX) with bevacizumab therapy as a first-line treatment for advanced colorectal cancer (CRC) in a prospective phase-II multi-institutional clinical trial (HiSCO-02 study). However, our prognostic data at the time lacked a sufficient observation period. Herein, we analyze the longer-term follow-up data, focusing on the status of eventual CVP implantation via an open-label, non-randomized, multicenter study. This study enrolled 55 patients (mean age, 64 years), of whom 43 died (41 of primary cancer). The median overall survival was 22.7 months (95% CI: 20.1-34.7 months). Post-treatment regimens after failure of first-line treatment were initiated in 43 patients; CPT11-based regimens were selected in most cases, and other oral FU combinations in nine. CVP was implanted in 35 patients prior to first-line treatment; eleven of the remaining 20 patients did not require CVP implantation. In conclusion, we report here the final prognostic update of the Phase II clinical trial examining the efficacy of SOX plus bevacizumab therapy, the results of which confirm the clinical efficacy of this regimen. |
| キーワード | metastatic colorectal cancer chemotherapy S-1 prospective phase II study |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 47 |
| 終了ページ | 52 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419314 |
| Web of Science KeyUT | 001203658200005 |
| JaLCDOI | 10.18926/AMO/66669 |
|---|---|
| フルテキストURL | 78_1_037.pdf |
| 著者 | Tanaka, Masato| Meena, Umesh| Taoka, Takuya| Fujiwara, Yoshihiro| Yokomizo, Daiichiro| Bashyal, Santosh Kumar| Sake, Naveen| Arataki, Shinya| |
| 抄録 | In adult spinal deformity (ASD) surgery, one of the key factors working to prevent proximal junctional kyphosis is the proximal anchor. The aim of this study was to compare clinical and radiographic outcomes of triangular fixation with conventional fixation as proximal anchoring techniques in ASD surgery. We retrospectively evaluated 54 patients who underwent corrective spinal fusion for ASD. Fourteen patients underwent proximal triangular fixation (Group T; average 74.6 years), and 40 patients underwent the conventional method (Group C; average 70.5 years). Clinical and radiographic outcomes were assessed using visual analogue scale (VAS) values for back pain and the Oswestry disability index (ODI). Radiographic evaluation was also collected preoperatively and postoperatively. Surgical times and intraoperative blood loss of the two groups were not significantly different (493 vs 490 min, 1,260 vs 1,173 mL). Clinical outcomes such as VAS and ODI were comparable in the two groups. Proximal junctional kyphosis in group T was slightly lower than that of group C (28.5% vs 47.5%, p=0.491). However, based on radiology, proximal screw pullout occurred significantly less frequently in the triangular fixation group than the conventional group (0.0% vs 22.5%, p=0.049). Clinical outcomes in the two groups were not significantly different. |
| キーワード | adult spinal deformity proximal junctional kyphosis triangular fixation minimally invasive surgery C arm free |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2024-02 |
| 巻 | 78巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 37 |
| 終了ページ | 46 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2024 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38419313 |
| Web of Science KeyUT | 001203658200003 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Iwamuro, Masaya| Takenaka, Ryuta| Toyokawa, Tatsuya| Kita, Masahide| Tsuzuki, Takao| Yoshioka, Masao| Gotoda, Tatsuhiro| Okanoue, Shotaro| Matsubara, Minoru| Sakaguchi, Chihiro| Otsuka, Motoyuki| |
| 備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-52633-z| |
| 発行日 | 2024-01-25 |
| 出版物タイトル | Scientific Reports |
| 巻 | 14巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 2202 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 38273039 |
| DOI | 10.1038/s41598-024-52633-z |
| Web of Science KeyUT | 001151714000020 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-024-52633-z |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Okatani, Takeshi| Nishimura, Midori Filiz| Egusa, Yuria| Yoshida, Sayako| Nishimura, Yoshito| Nishikori, Asami| Yoshino, Tadashi| Yamamoto, Hidetaka| Sato, Yasuharu| |
| キーワード | methotrexate-associated lymphoproliferative disorders other iatrogenic immunodeficiency-associated lymphoproliferative disorders lymphoproliferative disorders arising in immune deficiency/dysregulation NOTCH1 |
| 発行日 | 2024 |
| 出版物タイトル | Journal of Clinical and Experimental Hematopathology |
| 巻 | 64巻 |
| 号 | 1号 |
| 出版者 | Japanese Society for Lymphoreticular Tissue Research |
| 開始ページ | 1 |
| 終了ページ | 9 |
| ISSN | 1346-4280 |
| NCID | AA11556796 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 The Japanese Society for Lymphoreticular Tissue Research |
| 論文のバージョン | publisher |
| PubMed ID | 38281745 |
| DOI | 10.3960/jslrt.23038 |
| Web of Science KeyUT | 001155420800001 |
| 関連URL | isVersionOf https://doi.org/10.3960/jslrt.23038 |
| フルテキストURL | fulltext20240129-02.pdf |
|---|---|
| 著者 | Akazawa, Hidemasa| Hagiya, Hideharu| Koyama, Toshihiro| Otsuka, Fumio| |
| キーワード | Disseminated cryptococcosis Cryptococcal infection Epidemiology Trend analysis Regionality |
| 備考 | The version of record of this article, first published in Mycopathologia, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11046-023-00814-1| |
| 発行日 | 2024-01-17 |
| 出版物タイトル | Mycopathologia |
| 巻 | 189巻 |
| 号 | 1号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 8 |
| ISSN | 0301-486X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2024 |
| 論文のバージョン | publisher |
| PubMed ID | 38231420 |
| DOI | 10.1007/s11046-023-00814-1 |
| Web of Science KeyUT | 001144045400002 |
| 関連URL | isVersionOf https://doi.org/10.1007/s11046-023-00814-1 |
| 著者 | Suzuki, Shintaro| Barrientos, Tomás| Mejía, Héctor| Price, T. Douglas| |
|---|---|
| 備考 | © 2023 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Dec. 2025.| |
| 発行日 | 2024-02 |
| 出版物タイトル | Journal of Archaeological Science: Reports |
| 巻 | 53巻 |
| 出版者 | Elsevier BV |
| 開始ページ | 104348 |
| ISSN | 2352-409X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Elsevier Ltd. |
| 論文のバージョン | author |
| DOI | 10.1016/j.jasrep.2023.104348 |
| Web of Science KeyUT | 001143409600001 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.jasrep.2023.104348 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kobayashi, Hiroki| Ouchi, Tomoki| Kitamura, Wataru| Asakura, Shoji| Yano, Tomofumi| Takeda, Hiromasa| Tokuda, Yoshiyuki| Yoshino, Tadashi| Maeda, Yoshinobu| |
| キーワード | cold agglutinin disease severe acute respiratory syndrome coronavirus 2 sutimlimab |
| 発行日 | 2023-12-26 |
| 出版物タイトル | Journal of Clinical and Experimental Hematopathology |
| 巻 | 63巻 |
| 号 | 4号 |
| 出版者 | The Japanese Society for Lymphoreticular Tissue Research |
| 開始ページ | 246 |
| 終了ページ | 250 |
| ISSN | 1346-4280 |
| NCID | AA11556796 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 The Japanese Society for Lymphoreticular Tissue Research |
| 論文のバージョン | publisher |
| PubMed ID | 38148014 |
| DOI | 10.3960/jslrt.23040 |
| Web of Science KeyUT | 001134578000003 |
| 関連URL | isVersionOf https://doi.org/10.3960/jslrt.23040 |
| フルテキストURL | fulltext20240121-01.pdf |
|---|---|
| 著者 | Matsuo, Toshihiko| Iguchi, Daisuke| |
| キーワード | COVID-19 mRNA vaccine abducens nerve palsy optic neuritis optical coherence tomography neurology |
| 発行日 | 2024-01 |
| 出版物タイトル | Journal of Investigative Medicine High Impact Case Reports |
| 巻 | 12巻 |
| 出版者 | SAGE Publications |
| ISSN | 2324-7096 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2024 American Federation for Medical Research |
| 論文のバージョン | publisher |
| PubMed ID | 38243406 |
| DOI | 10.1177/23247096231225873 |
| Web of Science KeyUT | 001145427500001 |
| 関連URL | isVersionOf https://doi.org/10.1177/23247096231225873 |
| フルテキストURL | fulltext20231223-01.pdf |
|---|---|
| 著者 | Matsuo, Toshihiko| Tanaka, Takehiro| Yamada, Kiyoshi| Nose, Motoko| Tanimoto, Yasushi| |
| キーワード | debridement eyelid lacrimal sac Mycobacterium abscessus nontuberculous mycobacteria |
| 発行日 | 2023-12-21 |
| 出版物タイトル | Clinical Case Reports |
| 巻 | 11巻 |
| 号 | 12号 |
| 出版者 | Wiley |
| 開始ページ | e8364 |
| ISSN | 2050-0904 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 38130855 |
| DOI | 10.1002/ccr3.8364 |
| Web of Science KeyUT | 001128230600001 |
| 関連URL | isVersionOf https://doi.org/10.1002/ccr3.8364 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Shinoda-Ito, Yuki| Hirai, Anna| Omori, Kazuhiro| Ideguchi, Hidetaka| Yamamoto, Hideki| Kato, Fumino| Obata, Kyoichi| Ogawa, Tatsuo| Nakano, Keisuke| Nakadoi, Takato| Katsuyama, Eri| Ibaragi, Soichiro| Yamamoto, Tadashi| Nagatsuka, Hitoshi| Hirasawa, Akira| Takashiba, Shogo| |
| キーワード | Ligneous periodontitis Plasminogen deficiency PLG Behcet's disease Gingival hyperplasia |
| 備考 | The version of record of this article, first published in BMC Oral Health, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12903-023-03586-8| |
| 発行日 | 2023-11-08 |
| 出版物タイトル | BMC Oral Health |
| 巻 | 23巻 |
| 号 | 1号 |
| 出版者 | BMC |
| 開始ページ | 843 |
| ISSN | 1472-6831 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023. |
| 論文のバージョン | publisher |
| PubMed ID | 37940896 |
| DOI | 10.1186/s12903-023-03586-8 |
| Web of Science KeyUT | 001101860500001 |
| 関連URL | isVersionOf https://doi.org/10.1186/s12903-023-03586-8 |
| JaLCDOI | 10.18926/AMO/66161 |
|---|---|
| フルテキストURL | 77_6_671.pdf |
| 著者 | Minami, Daisuke| Hosoya, Takeshi| Hosoya, Masaharu| Nagano, Akichika| Nakajima, Yasuhiro| Miyahara, Nobuaki| Kanehiro, Arihiko| |
| 抄録 | A 74-year-old Japanese woman presented with a 45-year history of refractory asthma. She had been treated with inhaled corticosteroids, a long-acting β2-agonist, and a long-acting muscarinic antagonist for 6 months. She also had a repeated viral infection. Her condition had been characterized as a refractory asthma associated with type 2 and non-type 2 traits. We began treatment with tezepelumab. The control of the patient’s asthma symptoms and quality of life improved greatly within 1 month (changes in eosinophil count from 748 to 96 /μL, in FeNO from 32 to 17 ppb, in the Asthma Quality of Life Questionnaire score from 3.59 to 6.68, and in the Asthma Control Test score from 13 to 23). Tezepelumab was effective as an initial biologic agent for a patient with refractory asthma associated with type 2 and non-type 2 traits. |
| キーワード | tezepelumab biologic agent eosinophilic non-type 2 severe asthma |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-12 |
| 巻 | 77巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 671 |
| 終了ページ | 674 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38145943 |
| Web of Science KeyUT | 001164631200014 |
| JaLCDOI | 10.18926/AMO/66160 |
|---|---|
| フルテキストURL | 77_6_665.pdf |
| 著者 | Sakurai, Atsunobu| Uka, Mayu| Iguchi, Toshihiro| Tomita, Koji| Matsui, Yusuke| Kakiuchi, Yoshihiko| Kuroda, Shinji| Fujiwara, Toshiyoshi| Hiraki, Takao| |
| 抄録 | We report the case details of a 65-year-old Japanese man with an omental abscess that was discovered 43 days after he underwent a laparoscopic proximal gastrectomy for gastric cancer. His chief complaint was mild abdominal pain that had persisted for several days. The abscess was diagnosed as a rare postoperative complication. We hesitated to perform a reoperation given the invasiveness of general anesthesia and surgery, plus the possibility of postoperative adhesions and because the patient’s general condition was stable and he had only mild abdominal pain. Percutaneous drainage using a 10.2-F catheter was performed with the patient under conscious sedation and computed tomography–fluoroscopy guidance, with no complications. After the procedure, the size of the abscess cavity was remarkably reduced, and 23 days later the catheter was withdrawn. |
| キーワード | drainage omental abscess omental infarction proximal gastrectomy |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-12 |
| 巻 | 77巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 665 |
| 終了ページ | 669 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38145942 |
| Web of Science KeyUT | 001164631200013 |
| JaLCDOI | 10.18926/AMO/66159 |
|---|---|
| フルテキストURL | 77_6_655.pdf |
| 著者 | Endo, Hirosuke| Yamada, Kazuki| Tetsunaga, Tomonori| Namba, Yoshifumi| Sugimoto, Yoshihisa| Mitani, Shigeru| Nakata, Eiji| Ozaki, Toshifumi| |
| 抄録 | Most patients with developmental dysplasia of the hip (DDH) now receive closed-reduction treatment within 6 months after birth. The long-term outcomes of patients with late-detection DDH have remained unclear. We reviewed the clinical records of 18 patients who underwent Colonna capsular arthroplasty (n=8) or closed reduction (n=10) for developmental dysplasia of the hip as infants or young children and underwent total hip arthroplasty approximately in midlife. Both the Colonna capsular arthroplasty and closed reduction groups achieved good clinical results after total hip arthroplasty. However, the operating time was longer and the improvements of hip range of motion and clinical score were significantly worse in the Colonna capsular arthroplasty group than in the closed reduction group. |
| キーワード | developmental hip dysplasia long-term follow-up closed reduction Colonna capsular arthroplasty total hip arthroplasty |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-12 |
| 巻 | 77巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 655 |
| 終了ページ | 663 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38145941 |
| Web of Science KeyUT | 001164631200012 |
| JaLCDOI | 10.18926/AMO/66158 |
|---|---|
| フルテキストURL | 77_6_651.pdf |
| 著者 | Watanabe, Daisuke| Hasebe, Yohei| Mitsui, Hiroshi| Oishi, Naoki| Kasai, Shin| Akahane, Koshi| Kojika, Satoru| Inukai, Takeshi| |
| 抄録 | A patient was born with a mass at the base of the thumb approximately 1.5 cm in diameter on the radial side of the fingers. The mass had globular swelling filled with hemorrhagic fluid and was dark red. X-rays and histology of the excised specimen suggested the diagnosis of gangrene and torsion of polydactyly. Prenatal torsion of polydactyly is not a common occurrence; moreover, prenatal torsion of polydactyly has only been found in ulnar polydactyly. Our case is a novel case of radial polydactyly that was gangrenous at birth owing to prenatal torsion. Diagnosing such a mass at the base of the thumb is important. |
| キーワード | infant fingers thumb polydactyly torsion abnormality |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-12 |
| 巻 | 77巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 651 |
| 終了ページ | 653 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38145940 |
| Web of Science KeyUT | 001164631200011 |
| JaLCDOI | 10.18926/AMO/66157 |
|---|---|
| フルテキストURL | 77_6_647.pdf |
| 著者 | Kojima, Katsuhide| Takahashi, Yuka| Sugiyama, Soichi| Asano, Yudai| Okawa, Nanako| Makimoto, Satoko| Higaki, Fumiyo| Iguchi, Toshihiro| Hiraki, Takao| |
| 抄録 | A 67-year-old man was referred to our hospital for the diagnosis and treatment of prostate cancer. Multidisciplinary discussion led to intensity-modulated radiotherapy preceded by hormone therapy. Before radiotherapy, a biodegradable hydrogel spacer (HS) was placed between the prostate and rectum to reduce radiation injury risk. Three weeks postplacement, pelvic magnetic resonance imaging revealed HS migration into the pelvic vein. Subsequent whole-body contrast-enhanced computed tomography (CECT) revealed HS migration into the pulmonary artery. The patient showed no symptoms or clinical signs. Radiotherapy was completed uneventfully. Complete absorption of the migrated HS was confirmed using CECT images 5 months postplacement. |
| キーワード | hydrogel spacer prostate cancer radiotherapy pulmonary embolism |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-12 |
| 巻 | 77巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 647 |
| 終了ページ | 650 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38145939 |
| Web of Science KeyUT | 001164631200010 |
| JaLCDOI | 10.18926/AMO/66155 |
|---|---|
| フルテキストURL | 77_6_627.pdf |
| 著者 | Hibino, Yumi| Okazawa-Sakai, Mika| Yokoyama, Takanori| Fujimoto, Etsuko| Okame, Shinichi| Teramoto, Norihiro| Takehara, Kazuhiro| |
| 抄録 | To explore the incidence of abnormal vaginal cytology after total laparoscopic hysterectomy for the treatment of cervical intraepithelial neoplasia 3, we retrospectively analyzed the medical records of patients treated at NHO Shikoku Cancer Center (Japan) in 2014-2019. The cases of 99 patients who underwent a laparoscopic (n=36) or open (n=63) hysterectomy and postoperative follow-up were examined. Abnormal vaginal cytology was detected in 13.9% (5/36) of the laparoscopic-surgery (LS) group and 14.3% (9/63) of the open-surgery (OS) group. A vaginal biopsy was performed at the physicians’ discretion; one LS patient and six OS patients were diagnosed with vaginal intraepithelial neoplasia. The cumulative incidence of abnormal vaginal cytology at 3 years post-hysterectomy was 21.4% (LS group) and 20.5% (OS group), a nonsignificant difference. A multivariate analysis showed that age > 50 years was the only independent risk factor for abnormal vaginal cytology among the covariates examined including age; body mass index; histories of vaginal delivery, abdominal surgery, and smoking; and surgical approach (hazard ratio 8.11; 95% confidence interval 1.73-37.98; p=0.01). These results suggest that the occurrence of abnormal vaginal cytology after a hysterectomy may not be influenced by the laparoscopic procedure but is associated with older age. |
| キーワード | total laparoscopic hysterectomy vaginal intraepithelial neoplasia cervical intraepithelial neoplasia vaginal cytology risk factor |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-12 |
| 巻 | 77巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 627 |
| 終了ページ | 634 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38145937 |
| Web of Science KeyUT | 001164631200008 |
| JaLCDOI | 10.18926/AMO/66154 |
|---|---|
| フルテキストURL | 77_6_619.pdf |
| 著者 | Oe, Kenichi| Iida, Hirokazu| Sogawa, Shohei| Kobayashi, Fumito| Nakamura, Tomohisa| Saito, Takanori| |
| 抄録 | This study retrospectively evaluated 41 consecutive open reductions and internal fixations following primary or revision total hip arthroplasty, which required trochanteric claw plate fixation for greater trochanteric fracture or osteotomy between January 2008 and December 2020. The mean duration of clinical follow-up was 4.2 years (range, 1-13 years). The patients included 13 men and 28 women, with a mean age of 68 years (range, 32-87 years). The indications for intervention included trochanteric osteotomy, intraoperative fracture, and non-union including postoperative fracture in 6, 9, and 26 cases, respectively. The mean Merle d’Aubigné Clinical Score improved from 9.4 points (range, 5-15 points) pre-operatively, to 14.3 points (range, 9-18 points) at the last follow-up. Bone union occurred in 35 cases (85%), while implant breakage occurred in four cases. At the last follow-up, the mean Merle d’Aubigné Clinical Scores of bone union and non-union were 15.3 and 14.1, respectively (p=0.48). The Kaplan-Meier survival rate, with the endpoint being revision surgery for pain, non-union, dislocation, or implant breakage, at 10 years was 80.0% (95% confidence interval: 62.6-97.4%). Greater trochanteric fixation using a trochanteric claw plate yielded successful results. |
| キーワード | greater trochanteric fracture trochanteric osteotomy claw plate total hip arthroplasty |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-12 |
| 巻 | 77巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 619 |
| 終了ページ | 625 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38145936 |
| Web of Science KeyUT | 001164631200007 |
| JaLCDOI | 10.18926/AMO/66151 |
|---|---|
| フルテキストURL | 77_6_595.pdf |
| 著者 | Bando, Takashi| Chuma, Masayuki| Hamano, Hirofumi| Niimura, Takahiro| Okada, Naoto| Kondo, Masateru| Izumi, Yuki| Ishida, Shunsuke| Yoshioka, Toshihiko| Asada, Mizuho| Zamami, Yoshito| Takechi, Kenshi| Goda, Mitsuhiro| Miyata, Koji| Yagi, Kenta| Izawa-Ishizawa, Yuki| Azuma, Momoyo| Yanagawa, Hiroaki| Tasaki, Yoshikazu| Ishizawa, Keisuke| |
| 抄録 | There is a growing concern about the relationship between vancomycin-associated nephrotoxicity (VAN) and concomitant use of nephrotoxins. We examined this relationship by combined retrospective analyses of two real-world databases. Initially, the FDA Adverse Event Reporting System (FAERS) was analyzed for the effects of concomitant use of one or more nephrotoxins on VAN and the types of combinations of nephrotoxins that exacerbate VAN. Next, electronic medical records (EMRs) of patients who received vancomycin (VCM) at Tokushima University Hospital between January 2006 and March 2019 were examined to confirm the FAERS analysis. An elevated reporting odds ratio (ROR) was observed with increases in the number of nephrotoxins administered (VCM + one nephrotoxin, adjusted ROR (95% confidence interval [CI]) 1.67 [1.51-1.85]; VCM + ≥2 nephrotoxins, adjusted ROR [95% CI] 1.54 [1.37-1.73]) in FAERS. EMRs analysis showed that the number of nephrotoxins was associated with higher incidences of VAN [odds ratio: 1.99; 95% CI: 1.42-2.78]. Overall, concomitant use of nephrotoxins was associated with an increased incidence of VAN, especially when at least one of those nephrotoxins was a renal hypoperfusion medication (furosemide, non-steroidal anti-inflammatory drugs, and vasopressors). The concomitant use of multiple nephrotoxins, especially including renal hypoperfusion medication, should be avoided to prevent VAN. |
| キーワード | vancomycin-associated nephrotoxicity polypharmacy nephrotoxin spontaneous adverse event reporting database electronic medical records |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-12 |
| 巻 | 77巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 595 |
| 終了ページ | 605 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 38145933 |
| Web of Science KeyUT | 001164631200004 |