
| ID | 17156 |
| Eprint ID | 17156
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| フルテキストURL | |
| タイトル(別表記) | Low molecular proteins in the urine of patients with systemic lupus erythematosus Part 1. Measurement of urinary free light chains
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| 著者 |
難波 義夫
岡山大学医学部第三内科
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| 抄録 | The concentration of urinary free light chains was measured in 61 patients with systemic lupus erythematosus (SLE) by single radial immunodiffusion. The concentration was significantly increased in these patients, and was associated with hypocomplementemia and a high level of antibody to DNA. It also correlated with the clinical disease activity of SLE. It is postulated that increased free light chain in the urine of SLE patients is derived mostly from increased synthesis of light chain rather than from increased breakdown of intact immunoglobulins or decrease of catabolism during renal insufficiency. The measurement of urinary free light chains may offer information for evaluating disease activity in SLE patients.
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| キーワード | 全身性エリテマトーデス
遊離L鎖
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| 発行日 | 1980-12-30
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| 出版物タイトル |
岡山医学会雑誌
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| 出版物タイトル(別表記) | Journal of Okayama Medical Association
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| 巻 | 92巻
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| 号 | 11-12号
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| 出版者 | 岡山医学会
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| 出版者(別表記) | Okayama Medical Association
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| 開始ページ | 1107
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| 終了ページ | 1114
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| ISSN | 0030-1558
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| NCID | AN00032489
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| 資料タイプ |
学術雑誌論文
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| オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/92/11-12/92_11-12_1107/_article/-char/ja/
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| 関連URL | http://www.okayama-u.ac.jp/user/oma/index.html
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| 言語 |
日本語
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| 著作権者 | 岡山医学会
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| 論文のバージョン | publisher
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| 査読 |
有り
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| Eprints Journal Name | joma
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