| ID | 16213 |
| Eprint ID | 16213
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| フルテキストURL | |
| タイトル（別表記） | Studies on Complex-release Activity of Complement in Systemic Lupus Erythematosus -Using Peroxidase as an Antigen in the Immune Complex- Part 1. Studies on Measuring Complex-release Activity
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| 著者 |
相原 泰
岡山大学医学部第3内科学教室
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| 抄録 | A simplified method of measuring the complex-release activity (CRA) of complement using peroxidase (PO) as an antigen in the immune complex was studied. PO-anti PO rabbit IgG immune complex (PO-IC) was solubilized principally via the alternative pathway in the sera. When substrates, H(2)O(2) and 5-aminosalicylic acid, were added to solubilized PO-IC, absorbance of the mixture at O.D. 450nm increased with the amount of complement in a dose-dependent manner. The CRA of the complement in the sera was shown by the absorbance of the mixture. The CRA in various sera correlated with CH50. The CRA via the alternative pathway (ACRA) in sera also correlated with CRA, CH50 and ACH50.The above results indicate that this method of measuring the complex-release activity of complement using peroxidase as an antigen is simple and useful.
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| キーワード | 可溶化現象
immune complex
alternative complement pathway
全身性エリテマトーデス
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| 発行日 | 1984-02-28
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| 出版物タイトル |
岡山医学会雑誌
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| 出版物タイトル（別表記） | Journal of Okayama Medical Association
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| 巻 | 96巻
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| 号 | 1-2号
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| 出版者 | 岡山医学会
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| 出版者（別表記） | Okayama Medical Association
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| 開始ページ | 61
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| 終了ページ | 67
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| ISSN | 0030-1558
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| NCID | AN00032489
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| 資料タイプ |
学術雑誌論文
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| オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/96/1-2/96_1-2_61/_article/-char/ja/
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| 関連URL | http://www.okayama-u.ac.jp/user/oma/index.html
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| 言語 |
日本語
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| 著作権者 | 岡山医学会
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| 論文のバージョン | publisher
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| 査読 |
有り
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| Eprints Journal Name | joma
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