検索結果 15575 件
| JaLCDOI | 10.18926/AMO/58271 |
|---|---|
| フルテキストURL | 74_2_129.pdf |
| 著者 | Fukuma, Shogo| Shinya, Takayoshi| Soh, Junichi| Fukuhara, Ryuichiro| Ogawa, Nanako| Higaki, Fumiyo| Tanaka, Takehiro| Ichihara, Eiki| Hiraki, Takao| Toyooka, Shinichi| Kanazawa, Susumu| |
| 抄録 | The aim of this study was to explore enhancement patterns of different types of primary lung cancers on 2-phase dynamic computed tomography (CT). This study included 217 primary lung cancer patients (141 adenocarcinomas [ADs], 48 squamous cell carcinomas [SCCs], 20 small cell lung carcinomas [SCLCs], and 8 others) who were examined using a 2-phase dynamic scan. Regions of interest were identified and mean enhancement values were calculated. After excluding the 20 SCLCs because these lesions had different clinical stages from the other cancer types, the mean attenuation values and subtractions between phases were compared between types of non-small cell lung carcinomas (NSCLCs) using the Kruskal–Wallis test. Late phase attenuation and attenuation of the late minus unenhanced phase (LMU) of SCCs were significantly higher than those of ADs (p<0.05). To differentiate SCC and AD in the late phase, a threshold of 80.21 Hounsfield units (HU) gave 52.9% accuracy. In LMU, a threshold of 52.16 HU gave 59.3% accuracy. Dynamic lung CT has the potential to aid in differentiating among NSCLC types. |
| キーワード | differentiation dynamic computed tomography primary lung cancer enhancement pattern |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-04 |
| 巻 | 74巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 129 |
| 終了ページ | 135 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32341587 |
| Web of Science KeyUT | 000528278500006 |
| NAID | 120006839450 |
| JaLCDOI | 10.18926/AMO/58270 |
|---|---|
| フルテキストURL | 74_2_123.pdf |
| 著者 | Fukuhara, Ryuichiro| Shinya, Takayoshi| Fukuma, Shogo| Ogawa, Nanako| Masaoka, Yoshihisa| Tanaka, Takehiro| Marunaka, Hidenori| Arioka, Tadashi| Hiraki, Takao| Kaji, Mitsumasa| Kanazawa, Susumu| |
| 抄録 | The aim of this study was to evaluate the ability of pretreatment 90-min 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) to predict the extranodular spread of lymph node metastases in oral squamous cell carcinoma. We retrospectively reviewed the cases of 56 patients who underwent pretreatment 18F-FDG PET/CT and surgery with neck dissection. Maximum standardized uptake value, metabolic tumor volume, and total lesion glycolysis were measured for the 56 primary sites and maximum standardized uptake value was measured for 115 lymph node levels. Extranodular spread was present at 9 lymph node levels in 7 patients. Significant differences were found in metabolic tumor volume and total lesion glycolysis of the primary site, and in lymph node maximum standardized uptake value, between patients with and without extranodular spread (p<0.05). Combining primary site total lesion glycolysis and lymph node maximum standardized uptake volume at their respective optimal cutoffs, the sensitivity, specificity, and accuracy for predicting extranodular spread were 89%, 92%, and 92%, respectively. Pretreatment 18F-FDG PET/CT is useful for predicting extranodular spread in patients with oral squamous cell carcinoma. The combined use of primary site total lesion glycolysis and lymph node maximum standardized uptake value showed greater predictive value than either predictor singly. |
| キーワード | 18F-fluorodeoxyglucose positron emission tomography/computed tomography extranodular spread metastasis oral squamous cell carcinoma |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-04 |
| 巻 | 74巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 123 |
| 終了ページ | 128 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32341586 |
| Web of Science KeyUT | 000528278500005 |
| NAID | 120006839449 |
| JaLCDOI | 10.18926/AMO/58269 |
|---|---|
| フルテキストURL | 74_2_115.pdf |
| 著者 | Kotani, Sayoko| Kamada, Yasuhiko| Shimizu, Keiko| Sakamoto, Ai| Nakatsuka, Mikiya| Hiramatsu, Yuji| Masuyama, Hisashi| |
| 抄録 | Thrombosis in decidual vessels is one of the mechanisms of pregnancy loss. However, few studies have assessed the relation between platelet activation, which is known to cause of thrombosis, and recurrent pregnancy loss (RPL). We investigated platelet activation in women with RPL compared to controls by measuring plasma levels of platelet factor 4 (PF4) and β-thromboglobulin (βTG), and assessed correlations between PF4/βTG and coagulative risk factors associated with RPL. The study group included 135 women who had experienced two or more consecutive pregnancy losses. The control group included 28 age-matched healthy women who had never experienced pregnancy loss. PF4 and βTG plasma levels were significantly higher in the women with RPL than controls (PF4: 14.0 [8.0-20.0] vs. 9.0 [6.0-12.0] ng/ml, p=0.043; βTG: 42.0 [24.3-59.8] vs. 31.5 [26.6-36.4] ng/ml, p=0.002). There was a significant association between βTG and anti-phosphatidylethanolamine antibody immunoglobulin M (aPE IgM) (p=0.048). Among the women with RPL, 18 of those who were positive for PF4 (45%) and 18 of those who were positive for βTG (37%) were negative for all known coagulative risk factors associated with RPL. Measurements of PF4 and βTG may be important because they help identify women who are at risk of RPL. |
| キーワード | recurrent pregnancy loss platelet factor 4 β-thromboglobulin platelet activation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-04 |
| 巻 | 74巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 115 |
| 終了ページ | 122 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32341585 |
| Web of Science KeyUT | 000528278500004 |
| NAID | 120006839448 |
| JaLCDOI | 10.18926/AMO/58268 |
|---|---|
| フルテキストURL | 74_2_109.pdf |
| 著者 | Ogawa, Chikako| Nakamura, Keiichiro| Matsuoka, Hirofumi| Matsubara, Yuko| Haraga, Junko| Masuyama, Hisashi| |
| 抄録 | This study aimed to determine whether the risk conferred by gynecologic cancer (GC) as second primary cancer (SPC) differs from that associated with GC as first primary cancer (FPC). We investigated the correlations between FPC/SPC and the characteristics and prognoses of 1,645 GC patients (701 with cervical cancer [CC], 641 with endometrial cancer [EM], and 303 with ovarian cancer [OV]). The χ2 test and the Kaplan–Meier method were used to determine whether FPC/SPC and the characteristics and prognoses of GC patients. Of the SPC patients, 26 (3.7%) had CC, 53 (8.3%) had EM, and 31 (10.2%) had OV. The most common previous cancer type in SPC of GC patients was breast cancer, which was observed in 13 patients (50.0%) with CC, 23 (43.4%) with EM, and 16 (51.6%) with OV. In all patients with CC, EM, and OV as SPC, the stage was significantly associated with recurrence. There were no significant differences in the morbidity or mortality of CC, EM, or OV patients between those with FPC and those with SPC. The risk of SPC development in GC patients varied, ranging from 3.5% (CC) to 10.3% (OV) of patients. |
| キーワード | second primary cancer gynecologic cancer prognosis |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-04 |
| 巻 | 74巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 109 |
| 終了ページ | 114 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32341584 |
| Web of Science KeyUT | 000528278500003 |
| NAID | 120006839447 |
| JaLCDOI | 10.18926/AMO/58267 |
|---|---|
| フルテキストURL | 74_2_103.pdf |
| 著者 | Kawada, Yasumasa| Kubo, Toru| Baba, Yuichi| Hirota, Takayoshi| Tanioka, Katsutoshi| Yamasaki, Naohito| Kitaoka, Hiroaki| |
| 抄録 | This study examined whether switching from amlodipine and atorvastatin treatment using two pills to an equal dose of single-pill therapy is useful in Japanese outpatients. We retrospectively reviewed data obtained from 94 outpatients for whom treatment with two pills, namely amlodipine and atorvastatin, was switched to an equal dose of single-pill therapy in 11 hospitals. The criterion for enrollment in this study was that patients had switched their medication without changing other anti-hypertensive or anti-cholesterol drugs. Neither systolic nor diastolic blood pressure changed significantly after switching to an equal dose of single-pill therapy, whereas low-density lipoprotein (LDL) cholesterol levels significantly decreased after the medication was switched from 94±24 mg/dl to 89±17 mg/dl (p=0.015). A switch from medication with two separate pills of amlodipine and atorvastatin to an equal dose of single-pill therapy resulted in an overall decrease in LDL cholesterol. The results indicated that the switch to single-pill therapy might be a useful treatment. |
| キーワード | hypertension dyslipidemia single-pill therapy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-04 |
| 巻 | 74巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 103 |
| 終了ページ | 108 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32341583 |
| Web of Science KeyUT | 000528278500002 |
| NAID | 120006839446 |
| JaLCDOI | 10.18926/AMO/58266 |
|---|---|
| フルテキストURL | 74_2_95.pdf |
| 著者 | Kuba, Sayaka| Yamanouchi, Kosho| Morita, Michi| Sakimura, Chika| Inamasu, Eiko| Hatachi, Toshiko| Otsubo, Ryota| Matsumoto, Megumi| Yano, Hiroshi| Miyamoto, Junya| Sato, Shuntaro| Nakagawa, Hiroo| Kanetaka, Kengo| Takatsuki, Mitsuhisa| Nagayasu, Takeshi| Eguchi, Susumu| |
| 抄録 | We assessed the usefulness of ChemoCalc, a software package for calculating drug costs, in helping patients understand these costs. We randomly assigned, in a 1 : 1 ratio, 20 women who had undergone surgery for early breast cancer to a group that discussed adjuvant treatment with their physicians using the ChemoCalc software (ChemoCalc group) or a group that discussed adjuvant treatment without ChemoCalc (Usual Explanation group). The participants completed a five-grade evaluation questionnaire after these discussions. The primary endpoint was the intergroup comparison of the questionnaire scores regarding participants’ understanding of their treatment-associated drug costs. Median age was not significantly different between the ChemoCalc group and Usual Explanation group (57 vs. 50, respectively; p=0.27). Patients in the ChemoCalc group had a significantly higher perceived level of understanding of the drug cost than those in the Usual Explanation group (5 [4-5] vs. 2.5 [1-5], respectively; p=0.002). Scores related to the patients’ perception that understanding drug costs is an important part of breast cancer treatment were also higher in the ChemoCalc group than the Usual Explanation group (5 [2-5] vs. 3 [1-5], respectively; p=0.049). ChemoCalc was found to be useful for understanding drug costs. |
| キーワード | breast cancer drug costs ChemoCalc |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-04 |
| 巻 | 74巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 95 |
| 終了ページ | 101 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 32341582 |
| Web of Science KeyUT | 000528278500001 |
| NAID | 120006839445 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Makihara, Seiichiro| Kariya, Shin| Naito, Tomoyuki| Uraguchi, Kensuke| Matsumoto, Junya| Noda, Yohei| Okano, Mitsuhiro| Nishizaki, Kazunori| |
| キーワード | Negative pressure wound therapy false vocal cord perforation deep neck abscess larynx perforation head and neck fistula |
| 発行日 | 2020-04-02 |
| 出版物タイトル | SAGE Open Medical Case Reports |
| 巻 | 8巻 |
| 出版者 | SAGE Publications |
| 開始ページ | 2050313X20915415 |
| ISSN | 2050-313X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2020 |
| 論文のバージョン | publisher |
| DOI | 10.1177/2050313X20915415 |
| Web of Science KeyUT | 000523514000001 |
| 関連URL | isVersionOf https://doi.org/10.1177/2050313X20915415 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Takaya, Yoichi| Akagi, Teiji| Nakagawa, Koji| Nakayama, Rie| Miki, Takashi| Watanabe, Nobuhisa| Toh, Norihisa| Ito, Hiroshi| |
| 発行日 | 2020-03-03 |
| 出版物タイトル | Journal of Interventional Cardiology |
| 巻 | 2020巻 |
| 出版者 | Hindawi |
| 開始ページ | 6090612 |
| ISSN | 0896-4327 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 Yoichi Takaya et al. |
| 論文のバージョン | publisher |
| PubMed ID | 32206044 |
| DOI | 10.1155/2020/6090612 |
| Web of Science KeyUT | 000522373900001 |
| 関連URL | isVersionOf https://doi.org/10.1155/2020/6090612 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Katayama, Akihiro| Tone, Atsuhito| Watanabe, Mayu| Teshigawara, Sanae| Miyamoto, Satoshi| Eguchi, Jun| Nakatsuka, Atsuko| Shikata, Kenichi| Wada, Jun| |
| キーワード | Hypoglycemia Predictive low glucose management (PLGM) Type 1 diabetes mellitus (T1DM) Sensor-augmented pump therapy (SAP) |
| 備考 | This is a post-peer-review, pre-copyedit version of an article published in Diabetology International. The final authenticated version is available online at: http://dx.doi.org/10.1007/s13340-019-00408-7.| |
| 発行日 | 2019-09-16 |
| 出版物タイトル | Diabetology International |
| 巻 | 11巻 |
| 号 | 2号 |
| 出版者 | Springer |
| 開始ページ | 97 |
| 終了ページ | 104 |
| ISSN | 2190-1678 |
| NCID | AA12503387 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 32206479 |
| DOI | 10.1007/s13340-019-00408-7 |
| NAID | 40022198977 |
| Web of Science KeyUT | 000520711100004 |
| 関連URL | isVersionOf https://doi.org/10.1007/s13340-019-00408-7 |
| タイトル（別表記） | The 84th Annual Meeting of the Japanese Society of Balneology, Climatology and Physical Medicine (BCPM) |
|---|---|
| フルテキストURL | 131_171.pdf |
| 著者 | 光延 文裕| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 171 |
| 終了ページ | 172 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.131.171 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.131.171 |
| NAID | 130007782622 |
| フルテキストURL | 131_169-170.pdf |
|---|---|
| 著者 | 鎌野 周平| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 169 |
| 終了ページ | 170 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| タイトル（別表記） | Reforming the way doctors work |
|---|---|
| フルテキストURL | 131_165.pdf |
| 著者 | 浜田 淳| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 165 |
| 終了ページ | 167 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.131.165 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.131.165 |
| NAID | 130007782623 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tanaka, Yoshihiro| Oita, Masataka| Inomata, Shinichiro| Fuse, Toshiaki| Akino, Yuichi| Shimomura, Kohei| |
| キーワード | IGRT noncoplanar radiotherapy patient positioning uncertainty SRS SRT |
| 発行日 | 2020-01-20 |
| 出版物タイトル | Journal of Applied Clinical Medical Physics |
| 巻 | 21巻 |
| 号 | 2号 |
| 出版者 | Wiley |
| 開始ページ | 89 |
| 終了ページ | 97 |
| ISSN | 1526-9914 |
| NCID | AA12034060 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 31957975 |
| DOI | 10.1002/acm2.12820 |
| Web of Science KeyUT | 000508029800001 |
| 関連URL | isVersionOf https://doi.org/10.1002/acm2.12820 |
| タイトル（別表記） | Drug interaction（46. Blending change and interaction of an injection drug） |
|---|---|
| フルテキストURL | 131_161.pdf |
| 著者 | 森下 陽介| 江角 悟| 西原 茂樹| 北村 佳久| 千堂 年昭| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 161 |
| 終了ページ | 164 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.131.161 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.131.161 |
| NAID | 130007782628 |
| タイトル（別表記） | Revision of the postgraduate clinical training system |
|---|---|
| フルテキストURL | 131_159.pdf |
| 著者 | 佐藤 明香| 小川 弘子| 三好 智子| 大塚 文男| |
| キーワード | 医師臨床研修制度 (postgraduate clinical training system) 研修医 (resident) |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 159 |
| 終了ページ | 160 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.131.159 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.131.159 |
| NAID | 130007782625 |
| タイトル（別表記） | Hereditary colorectal cancer in clinical practice, in coordination with a patients’ association |
|---|---|
| フルテキストURL | 131_153.pdf |
| 著者 | 田中屋 宏爾| |
| キーワード | 患者会 遺伝性大腸癌 リンチ症候群 家族性大腸腺腫症 |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 153 |
| 終了ページ | 157 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.131.153 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.131.153 |
| NAID | 130007782626 |
| タイトル（別表記） | Emergency medical treatment of patients undergoing otolaryngology in the southeastern part of Okayama Prefecture |
|---|---|
| フルテキストURL | 131_145.pdf |
| 著者 | 秋定 直樹| 石原 久司| 宇野 雅子| 赤木 祐介| 梶原 壮平| 福本 晶| 若林 時生| 竹内 彩子| 秋定 健| |
| 抄録 | To clarify the scenario regarding the emergency medical treatment of patients undergoing otolaryngology in southeastern Okayama Prefecture in Japan, we evaluated the conditions in three hospitals that mainly provide emergency medical treatment to patients undergoing otorhinolaryngology at night or on holidays. The data (age, sex, type of disease, and address) of patients who visited Japanese Red Cross Okayama Hospital, Kawasaki Medical School General Medical Center, and Okayama Medical Center in 2018 were collected and compared. All three hospitals reported many cases of tonsillar abscess and nasal bleeding. In the study population, the number of patients aged ≤10 and 10-20 years were the lowest and highest, respectively. Patients residing in southern Okayama City and Tamano City tended to visit Japanese Red Cross Okayama Hospital or Kawasaki Medical School General Medical Center. Patients residing in northeastern Okayama Prefecture and northern Okayama City tended to visit Okayama Medical Center. A ceiling for the senior physicians’ capacity will be introduced in April 2020, and thus the number of otolaryngology-related treatments performed in Okayama Prefecture is expected to decrease. The otolaryngologyrelated emergency medical treatment in southeastern Okayama Prefecture may collapse. Emergency medical care systems must therefore be considered in the future. |
| キーワード | 耳鼻咽喉科 (otolaryngology) 救急体制 (emergency system) 働き方改革 (work style reform) 専門医制度 (specialist system) 地域医療 (regional medical care) |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 145 |
| 終了ページ | 152 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.131.145 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.131.145 |
| NAID | 130007782629 |
| タイトル（別表記） | Efficacy of Helicobacter pylori eradication followed by the administration of a proton pump inhibitor (PPI) or PPI plus a prokinetic in H. pylori-positive patients with dyspepsia |
|---|---|
| フルテキストURL | 131_139.pdf |
| 著者 | 三浦 公| 岩室 雅也| 豊川 達也| 竹中 龍太| 井上 雅文| 伊藤 守| 岡田 裕之| |
| 抄録 | To investigate whether treatment comprised of Helicobacter pylori eradication followed by the administration of a proton pump inhibitor (PPI) alone and a dual treatment with a PPI plus a prokinetic agent helps relieve symptoms, we treated 26 patients with H. pylori infection and dyspepsia with the sequential treatment and assessed their symptoms. Scores for gastroesophageal reflux disease (GERD) and dyspepsia in a modified F-scale were significantly improved after the eradication of H. pylori, and symptoms were completely relieved in 13 patients. The remaining 13 patients received 4-week treatment with the PPI rabeprazole, and their GERD scores significantly improved after the treatment. The symptoms of five patients completely disappeared ; the other eight patients required dual treatment with a PPI plus the prokinetic acotiamide. Early satiety tended to be relieved after the dual treatment, but the improvement was not significant. Thus, in patients with dyspepsia and an H. pylori infection, the H. pylori should be eradicated first. The administration of a PPI is useful in patients with GERD symptoms, and a PPI+ acotiamide may be beneficial for residual symptoms of early satiety. |
| キーワード | 機能性ディスペプシア (functional dyspepsia) ヘリコバクター・ピロリ (Helicobacter pylori) プロトンポンプ阻害剤 (proton pomp inhibitor) 消化管運動機能改善剤 (acotiamide) |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 139 |
| 終了ページ | 143 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.131.139 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.131.139 |
| NAID | 130007782646 |
| タイトル（別表記） | The 2018 Incentive Award of the Okayama Medical Association in Neuroscience (2018 Niimi Prize) |
|---|---|
| フルテキストURL | 131_135.pdf |
| 著者 | 枝松 緑| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 135 |
| 終了ページ | 137 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.131.135 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.131.135 |
| NAID | 130007782643 |
| タイトル（別表記） | The 2018 Incentive Award of the Okayama Medical Association in General Medical Science (2018 Yuuki Prize) |
|---|---|
| フルテキストURL | 131_131.pdf |
| 著者 | 高 遠| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2019-12-02 |
| 巻 | 131巻 |
| 号 | 3号 |
| 開始ページ | 131 |
| 終了ページ | 133 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.131.131 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2019 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.131.131 |
| NAID | 130007782645 |