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JaLCDOI 10.18926/AMO/47016
フルテキストURL 65_5_335.pdf
著者 Sakamoto, Yuichi| Mariya, Yasushi| Oshikiri, Toshiyuki| Sasaki, Sumiko| Segawa, Megumi| Teshiromori, Ryuichi| Ogura, Kazuto| Akagi, Tomoaki| Kaimori, Mitsuomi| Kubo, Kohmei|
抄録 Chronic myeloid leukemia (CML) is caused by the BCR-ABL oncogene. The Philadelphia chromosome (Ph) from a reciprocal translocation, t(9;22) (q34;q11) causes a fusion gene, BCR-ABL, that encodes a constitutively active tyrosine kinase. Treatment of CML by imatinib is effective to control the tyrosyl phosphorylation of the protein related to the cell signaling. BCR-ABL mRNA is overexpressed in the minimal residual disease (MRD), known as an early sign of relapse. Between December 2005 and June 2008, we measured BCR-ABL mRNA levels in the bone marrow (BM) from patients by quantitative real-time polymerase chain reaction (RQ-PCR) in Aomori Prefectural Central Hospital. Eighty-six samples from 26 patients were collected. Among the 26 CML patients, 11 patients (42%) were in the pretreatment group. Seven (64%) of the 11 patients achieved complete molecular response (CMR). In the post-treatment group consisting of the remaining 15 patients, 9 (60%) patients achieved CMR. The patients receiving imatinib at a dose over 300mg per day required 13 (6-77) months [median (range)] to achieve CMR. On the other hand, the patients receiving a dose below 300mg per day required 29.5 (11-84) months [median (range)]. When BCR-ABL mRNA was detected during the treatment course of patients with CMR, careful observation of BCR-ABL mRNA was useful for tracking the clinical course of patients. In conclusion, the BCR-ABL mRNA level was useful for monitoring the clinical course in 26 patients with CML.
キーワード chronic myeloid leukemia (CML) BCR-ABL minimal residual disease (MRD) imatinib mesylate real-time quantitative PCR (RQ-PCR)
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-10
65巻
5号
出版者 Okayama University Medical School
開始ページ 335
終了ページ 342
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037271
Web of Science KeyUT 000296116400008
JaLCDOI 10.18926/AMO/47015
フルテキストURL 65_5_329.pdf
著者 Matsumoto, Yoshinori| Sada, Ken-ei| Takano, Mariko| Toyota, Noriko| Yamanaka, Ryutaro| Sugiyama, Koichi| Wakabayashi, Hiroshi| Kawabata, Tomoko| Otsuka, Fumio| Makino, Hirofumi|
抄録 It is well known that infection is one of the major causes of morbidity and mortality in rheumatic disease patients treated with high-dose glucocorticoids, especially in the early phase after achievement of disease remission. The aim of this study was to identify the risk factors for infection, with a focus on the dose of glucocorticoids administered, following the achievement of disease remission in rheumatic diseases patients. We retrospectively analyzed the medical records of rheumatic disease patients who had been treated with glucocorticoids. The primary endpoint was the incidence rate of infection during a period from 1 to 2 months after the commencement of treatment. From April 2006 to March 2010, 19 of 92 patients suffered from infection during the observation period. Age≧65 yrs, presence of interstitial pneumonia, diagnosis of systemic vasculitis and serum creatinine level≧2.0mg/dl were found to be univariate predictors for infection. However, only the presence of interstitial pneumonia was an independent risk factor for infection (HR=4.50, 95%CI=1.65 to 14.44) by the Cox proportional hazard model. Even after achievement of clinical remission, careful observation is needed for patients with interstitial pneumonia, more so than for those receiving high-dose glucocorticoids.
キーワード infection rheumatic disease glucocorticoids interstitial pneumonia risk factors
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-10
65巻
5号
出版者 Okayama University Medical School
開始ページ 329
終了ページ 334
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037270
Web of Science KeyUT 000296116400007
JaLCDOI 10.18926/AMO/47014
フルテキストURL 65_5_325.pdf
著者 Hu, Hai| Zhu, Jiang Fan| Huang, An Hua| Xin, Ying| Xu, An An| Chen, Bingguan|
抄録 To further improve our developed transumbilical endoscopic surgery (TUES), we developed a completely covert laparoscopic cholecystectomy (LC). Twelve cases of LC were recruited for this new approach. First, a 10-mm trocar was placed above the umbilicus for inserting the laparoscope. Two 5-mm trocars were then placed near the right and left ends of the superior margin of the suprapubic hair. After the 5-mm 30° laparoscope was shifted to the left suprapubic trocar, the harmonic scalper, electric hook, and grasper were inserted either through the 10-mm umbilical trocar or through the right suprapubic trocar. All gallbladders were successfully removed without intraoperative complications. The mean operating time was 28.5±5.7min (range 20-45min). All patients felt well after surgery and did not need postoperative analgesia. They resumed free oral intake 6h after the procedure. All patients were satisfied with the appearance of the incisions, which were completely hidden in the umbilicus and suprapubic hair. The approach we developed has overcome both external instrument interference around the umbilicus and the loss of triangulation in the operative field. It is relatively simpler than a typical TUES and offers better cosmetic results.
キーワード laparoscopy cholecystectomy scarless surgery
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-10
65巻
5号
出版者 Okayama University Medical School
開始ページ 325
終了ページ 328
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037269
Web of Science KeyUT 000296116400006
JaLCDOI 10.18926/AMO/47013
フルテキストURL 65_5_315.pdf
著者 Wang, Lei| Kaku, Haruki| Huang, Peng| Xu, Kexin| Yang, Kai| Zhang, Jiheng| Li, Ming| Xie, Liping| Wang, Xiaofeng| Sakai, Akiko| Watanabe, Masami| Nasu, Yasutomo| Shimizu, Kenji| Kumon, Hiromi| Na, Yanqun|
抄録 Deficiencies in the human DNA repair gene WRN are the cause of Werner syndrome, a rare autosomal recessive disorder characterized by premature aging and a predisposition to cancer. This study evaluated the association of WRN Leu1074Phe (rs1801195), a common missense single nucleotide polymorphism in WRN, with prostate cancer susceptibility in Chinese subjects. One hundred and forty-seven prostate cancer patients and 111 male cancer-free control subjects from 3 university hospitals in China were included. Blood samples were obtained from each subject, and the single nucleotide polymorphism WRN Leu1074Phe was genotyped by using a Snapshot assay. The results showed that WRN Leu1074Phe was associated with the risk of prostate cancer in Chinese men and that the TG/GG genotype displayed a decreased prevalence of prostate cancer compared with the TT genotype (OR=0.58, 95%CI:0.35-0.97, p=0.039). Through stratified analysis, more significant associations were revealed for the TG/GG genotype in the subgroup with diagnosis age <_ 72 yr (OR=0.27, 95%CI:0.12-0.61, p=0.002) and in patients with localized diseases (OR=0.36, 95%CI:0.19-0.70, p=0.003). However, no statistically significant difference was found in the subgroup with age >72 yr or in patients with advanced diseases. We concluded that the genetic variant Leu1074Phe in the DNA repair gene WRN might play a role in the risk of prostate cancer in Chinese subjects.
キーワード polymorphism prostatic neoplasms single nucleotide susceptibility WRN
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-10
65巻
5号
出版者 Okayama University Medical School
開始ページ 315
終了ページ 323
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037267
Web of Science KeyUT 000296116400005
JaLCDOI 10.18926/AMO/47012
フルテキストURL 65_5_307.pdf
著者 Shiraki, Teruo| Saito, Daiji|
抄録 Factors contributing to the sex difference of in-hospital mortality after acute myocardial infarction (MI) are still unknown. We compared the clinical characteristics on admission and in-hospital outcome of consecutive 1,354 patients with acute MI between the 2 sexes. Age on admission was about 7 years older in women than in men. In-hospital death was significantly more frequent in women. Pulmonary congestion and hypertension were more likely in women with higher serum levels of total cholesterol and LDL cholesterol. A higher prevalence of current smoking and inferior wall involvement and lower serum HDL cholesterol level were observed in man. After adjusting for age, adverse in-hospital mortality for women was observed in both younger and older patients. Multivariate logistic regression analysis demonstrated that age, location of infarction, recanalization and serum C-reactive protein (CRP) concentration were independent predictors for in-hospital mortality for overall patients, while age and recanalization were independent predictors for male gender, and pulmonary congestion and serum CRP concentration were independent predictors for female gender. In-hospital outcome after acute MI was worse in women. A multivariate logistic regression model revealed that the sexually different factors affected in-hospital mortality in females.
キーワード sex difference acute myocardial infarction inferior infarction in-hospital mortality age difference
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-10
65巻
5号
出版者 Okayama University Medical School
開始ページ 307
終了ページ 314
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037267
Web of Science KeyUT 000296116400004
JaLCDOI 10.18926/AMO/47011
フルテキストURL 65_5_299.pdf
著者 Itani, Miki| Yamamoto, Yuji| Doi, Yusuke| Miyaishi, Satoru|
抄録 Postmortem degradation of DNA was quantitatively estimated. Brain, liver, kidney and muscle samples were obtained from sacrificed rats left at 20℃ or 4℃. The quantity of DNA was measured by real-time PCR using a primer set for a sequence in the Rsrc 1 gene. When the quantity of amplified DNA using 10ng Human Genomic DNA was defined as 100 RFU, the quantities in the brain, liver, kidney and skeletal muscle (each 2μg of dry weight) on the day of sacrifice were 253±11, 338±22, 556±14 and 531±12 Relative Fluorescence Units (RFU), respectively (mean±S.E., n=5). The quantity of amplified DNA decreased to below 10 RFU in 1-3 weeks in the liver, kidney and skeletal muscle at 20℃, while that in the brain was more than 10 RFU for six weeks, demonstrating the usefulness of the brain as a sample for DNA analysis of decaying corpses. It was suggested that quantifying the amplified DNA in the brain at 20℃ and in the liver at 4℃ as well as the ratio of the quantity of amplified DNA in the liver to the brain at 4℃ might be useful for diagnosing time of death. This study provides the first quantitative analysis of the postmortem progress of DNA degradation in the corpse.
キーワード DNA degradation postmortem interval personal identification
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2011-10
65巻
5号
出版者 Okayama University Medical School
開始ページ 299
終了ページ 306
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037266
Web of Science KeyUT 000296116400003
JaLCDOI 10.18926/AMO/47010
フルテキストURL 65_5_287.pdf
著者 Hiraki, Takao| Gobara, Hideo| Mimura, Hidefumi| Toyooka, Shinichi| Fujiwara, Hiroyasu| Yasui, Kotaro| Sano, Yoshifumi| Iguchi, Toshihiro| Sakurai, Jun| Tajiri, Nobuhisa| Mukai, Takashi| Matsui, Yusuke| Kanazawa, Susumu|
抄録 The application of radiofrequency ablation for the treatment of lung cancer by our group at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences began in June 2001, and in the present report, we review our 10-year experience with this treatment modality at Okayama University Hospital. The local efficacy of radiofrequency ablation for the treatment of lung cancer depends on tumor size and the type of electrode used, but not on tumor type. An important factor for the prevention of local failure may be the acquisition of an adequate ablative margin. The combination of embolization and radiation therapy enhances the local efficacy. Local failure may be salvaged by repeating the radiofrequency ablation, particularly in small tumors. Survival rates after radiofrequency ablation are quite promising for patients with clinical stage I non-small cell lung cancer and pulmonary metastasis from colorectal cancer, hepatocellular carcinoma, and renal cell carcinoma. The complications caused by radiofrequency ablation can be treated conservatively in the majority of cases. However, attention should be paid to rare but serious complications. This review shows that radiofrequency ablation is a promising treatment for patients with lung cancer.
キーワード radiofrequency ablation lung cancer local efficacy survival complication
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2011-10
65巻
5号
出版者 Okayama University Medical School
開始ページ 287
終了ページ 297
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037265
Web of Science KeyUT 000296116400002
JaLCDOI 10.18926/AMO/47009
フルテキストURL 65_5_279.pdf
著者 Miyoshi, Ko| Kasahara, Kyosuke| Miyazaki, Ikuko| Asanuma, Masato|
抄録 Almost all mammalian cells carry one primary cilium that functions as a biosensor for chemical and mechanical stimuli. Genetic damages that compromise cilia formation or function cause a spectrum of disorders referred to as ciliapathies. Recent studies have demonstrated that some pharmacological agents and extracellular environmental changes can alter primary cilium length. Renal injury is a well-known example of an environmental insult that triggers cilia length modification. Lithium treatment causes primary cilia to extend in several cell types including neuronal cells;this phenomenon is likely independent of glycogen synthase kinase-3β inhibition. In renal epithelial cell lines, deflection of the primary cilia by fluid shear shortens them by reducing the intracellular cyclic AMP level, leading to a subsequent decrease in mechanosensitivity to fluid shear. Primary cilium length is also influenced by the dynamics of actin filaments and microtubules through the levels of soluble tubulin in the cytosol available for primary cilia extension. Thus, mammalian cells can adapt to the extracellular environment by modulating the primary cilium length, and this feedback system utilizing primary cilia might exist throughout the mammalian body. Further investigation is required concerning the precise molecular mechanisms underlying the control of primary cilium length in response to environmental factors.
キーワード primary cilium length lithium cyclic AMP soluble tubulin intraflagellar transport
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2011-10
65巻
5号
出版者 Okayama University Medical School
開始ページ 279
終了ページ 285
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2011 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 22037264
Web of Science KeyUT 000296116400001
著者 Tsukamoto, Naoko| Otsuka, Fumio| Miyoshi, Tomoko| Inagaki, Kenichi| Nakamura, Eri| Suzuki, Jiro| Ogura, Toshio| Iwasaki, Yasumasa| Makino, Hirofumi|
発行日 2011-01-30
出版物タイトル Molecular and Cellular Endocrinology
332巻
1-2号
資料タイプ 学術雑誌論文
著者 Kishimoto, Akira| Takagawa, Yuto| Teranishi, Takashi| Hayashi, Hidetaka|
発行日 2011-07-31
出版物タイトル Materials Letters
65巻
14号
資料タイプ 学術雑誌論文
著者 Faculty of Engineering, Okayama University|
発行日 2001-12
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
36巻
1号
資料タイプ その他
JaLCDOI 10.18926/47005
フルテキストURL mfe_36_1_117_121.pdf
著者 Shirosaki, Yuki| Tsuru, Kanji| Hayakawa, Satoshi| Osaka, Akiyoshi| Takashima, Seisuke|
抄録 γ-Methacryloxypropyltrimethoxysilane (γ-MPS) was grafted to silicone due to emulsion polymerization to induce Si-OH groups, in order to provide silicone with bioactivity spontaneous deposition of apatite in body fluid and to improve cytocompatibility. Apatite deposited on the grafted silicone within 7 days of soaking in 1.5 times as concentrated as the Kokubo solution. Osteoblastic cells (MC3T3-E1) were cultured on the specimens up to 7 days. After 5 days of culture, the number of MC3T3-E1 cells on the grafted specimen was much greater than that on the original specimen. These results indicated that the biocompatibility of silicone elastomer was improved by the grafting γ-MPS.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
36巻
1号
開始ページ 117
終了ページ 121
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120003497031
JaLCDOI 10.18926/47004
フルテキストURL mfe_36_1_107_116.pdf
著者 Kanatani, Kenichi| Ohta, Naoya|
抄録 We present a new method for automatically detecting circular objects in images: we detect an osculating circle to an elliptic arc using a Hough transform, iteratively deforming it into an ellipse, removing outlier pixels, and searching for a separate edge. The voting space is restricted to one and two dimensions for efficiency, and special weighting schemes are introduced to enhance the accuracy. We demonstrate the effectiveness of our method using real images. Finally, we apply our method to the calibration of a turntable for 3-D object shape reconstruction.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
36巻
1号
開始ページ 107
終了ページ 116
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80012855284
JaLCDOI 10.18926/47003
フルテキストURL mfe_36_1_091_106.pdf
著者 Kanatani, Kenichi| Ohta, Naoya|
抄録 We present a theoretically optimal linear algorithm for 3-D reconstruction from point correspondences over two views. We also present a similarly constructed optimal linear algorithm for 3-D reconstruction from optical flow. We then compare the performance of the two algorithms by simulation and real-image experiments using the same data. This is the first impartial comparison ever done in the sense that the two algorithms are both optimal, extracting the information contained in the data to a maximum possible degree. We observe that the finite motion solution is always superior to the optical flow solution and conclude that the finite motion algorithm should be used for 3-D reconstruction.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
36巻
1号
開始ページ 91
終了ページ 106
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120003497029
JaLCDOI 10.18926/47002
フルテキストURL mfe_36_1_079_090.pdf
著者 Kanatani, Kenichi|
抄録 We first present an improvement of Kanatani's subspace separation [8] for motion segmentation by newly introducing the affine space constraint. We point out that this improvement does not always fare well due to the effective noise it introduces. In order to judge which solution to adopt if different segmentations are obtained, we present two criteria: one is the standard F test; the other is model selection using the geometric AIC of Kanatani [7] and the geometric MDL of Matsunaga and Kanatani [13]. We test these criteria doing real image experiments.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
36巻
1号
開始ページ 79
終了ページ 90
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120003497028
JaLCDOI 10.18926/47001
フルテキストURL mfe_36_1_059_077.pdf
著者 Kanatani, Kenichi|
抄録 Contrasting "geometric fitting", for which the noise level is taken as the asymptotic variable, with "statistical inference", for which the number of observations is taken as the asymptotic variable, we give a new definition of the "geometric AIC" and the "geometric MDL" as the counterparts of Akaike's AIC and Rissanen's MDL. We discuss various theoretical and practical problems that emerge from our analysis. Finally, we show, doing experiments using synthetic and real images, that the geometric MDL does not necessarily outperform the geometric AIC and that the two criteria have very different characteristics.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
36巻
1号
開始ページ 59
終了ページ 77
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80012855281
JaLCDOI 10.18926/47000
フルテキストURL mfe_36_1_051_057.pdf
著者 Vaillancourt, Chico|
抄録 This is a brief essay on using kinesthetic approaches to learning English as a second language. In the essay, I briefly discuss teaching philosophy and 2 small-scale Technical Engineering projects that I have introduced and completed with my 4(th) year engineering students in the spring of 2001.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
36巻
1号
開始ページ 51
終了ページ 57
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120003497026
JaLCDOI 10.18926/46999
フルテキストURL mfe_36_1_041_049.pdf
著者 Totsuji, Hiroo| Kishimoto, Tokunari| Totsuji, Chieko| Tsuruta, Kenji|
抄録 The ground state of spherical clusters of charged particles of one species confined by the three-dimensional parabolic potential is investigated by molecular dynamics simulations with the system size from N = 5000 to N = 1.2 × 10(5) . The cohesive energy per particle is compared between the shell-structured clusters and spherical finite bcc lattices with relaxed surfaces, the former and the latter being the ground states for small systems and for the large enough systems, respectively. It is shown that, when N > N(c)(N(c) > N), finite bcc lattices with relaxed surfaces (the shell structures) have stronger cohesion than the shell structures (finite bcc lattices with relaxed surfaces) and the critical value of the transition N(c) is estimated to be 10(4) < N(c) < 1.4 × 10(4) . The nucleation of the bcc lattice in the shell-structured cluster of 2 × 10(4) ions is observed.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
36巻
1号
開始ページ 41
終了ページ 49
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80015112663
JaLCDOI 10.18926/46998
フルテキストURL mfe_36_1_029_039.pdf
著者 Imai, Jun| Wada, Kiyoshi|
抄録 A procedure for control-oriented modeling is proposed for large flexible structures with unknown modal parameters. Techniques on quantification of errors in modal truncated nominal models are developed for the case where a finite number of upper and lower bounds of the unknown modal parameters are given. A feasible set of systems matching the conditions is introduced, and then error bounds covering the feasible set are established in the frequency domain. The bounds are easily checked using linear programming for any user-specified frequency. The feasibility of the proposed scheme is illustrated by numerical study on an ideal flexible beam example.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
36巻
1号
開始ページ 29
終了ページ 39
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 80012887118
JaLCDOI 10.18926/46997
フルテキストURL mfe_36_1_017_028.pdf
著者 Endo, Shinichiro| Konishi, Masami|
抄録 Small Scale Hydroelectric Power Generation is made using the water drop caused by the gradient difference between that of the river and that of the penstock. The water flow in this system apt to vary with time. Especially, at the time of the flood or that of the dry, the flow in the water stream varies largely. To realize the stable generation, it is necessary to maintain the water level in the head tank located in the mid way in the stream channel at a constant level. In this paper, variation of water level is forecasted using two-tank model for the penstock and the head tank and the water level control algorithm is proposed by deadbeat control. The effectiveness of the algorithm is evaluated beforehand using the simulation program of the water environment for the hydroelectric generation system.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 2001-12
36巻
1号
開始ページ 17
終了ページ 28
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120003497023