start-ver=1.4
cd-journal=joma
no-vol=25
cd-vols=
no-issue=
article-no=
start-page=e5
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2026
dt-pub=2026
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Effects of sagging correction calibration error on radiation therapy equipment using image analysis
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Purpose: This study investigates the effect of sagging correction errors on image quality and geometric coordinate accuracy.
Methods: This study utilised the Elekta radiotherapy system, ball bearing (BB), Catphan phantom and MultiMet-WL phantom. Ten distinct flex maps (FMs) were acquired by positioning the BB at the accuracy isocentre and introducing shifts of 0.2, 0.4 and 0.6 mm in the left, table and up directions, respectively. Cone-beam computed tomography images of the Catphan phantom were acquired using 10 FMs. The images were analysed for modulation transfer function (MTF) values and geometric coordinates. Additionally, the Winston?Lutz (W-L) test was conducted under reference couch positions and with a 0.3 mm couch shift.
Results: For the Catphan phantom analysis, the standard deviations of MTF10% across FMs were 0.19. The centre-of-gravity coordinates of the insert exhibited shifts of approximately 0.2, 0.4 and 0.6 mm when comparing reference images to those acquired with the shifted FMs. The results of the W-L test with a 0.3 mm couch shift showed radiation isocentre deviations exceeding 1 mm compared to the reference couch positions.
Conclusions: Minor sagging correction calibration errors did not remarkably impact image quality; however, they altered the geometric coordinates of the image isocentre. These calibration errors decreased the accuracy of off-isocentre positioning.
en-copyright=
kn-copyright=
en-aut-name=FujiiYasushi
en-aut-sei=Fujii
en-aut-mei=Yasushi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=NakayamaTakahiro
en-aut-sei=Nakayama
en-aut-mei=Takahiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=OshitaJunki
en-aut-sei=Oshita
en-aut-mei=Junki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TsunodaAyaka
en-aut-sei=Tsunoda
en-aut-mei=Ayaka
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=SaekiYusuke
en-aut-sei=Saeki
en-aut-mei=Yusuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=TanabeYoshinori
en-aut-sei=Tanabe
en-aut-mei=Yoshinori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
affil-num=1
en-affil=Department of Radiology, Chugoku Central Hospital of the Mutual Aid Association of Public School Teachers
kn-affil=
affil-num=2
en-affil=Department of Radiology, Chugoku Central Hospital of the Mutual Aid Association of Public School Teachers
kn-affil=
affil-num=3
en-affil=Department of Radiology, Chugoku Central Hospital of the Mutual Aid Association of Public School Teachers
kn-affil=
affil-num=4
en-affil=Department of Radiology, Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=5
en-affil=Department of Radiological Technology, Kawasaki Medical School Hospital
kn-affil=
affil-num=6
en-affil= Faculty of Medicine, Graduate School of Health Sciences, Okayama University
kn-affil=
en-keyword=flex map
kn-keyword=flex map
en-keyword=sagging
kn-keyword=sagging
en-keyword=Winston?Lutz test
kn-keyword=Winston?Lutz test
END
start-ver=1.4
cd-journal=joma
no-vol=75
cd-vols=
no-issue=1
article-no=
start-page=13
end-page=19
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2026
dt-pub=20260315
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=自然起源放射性物質(NORM)を用いた232Th/212Pbジェネレーターによる短寿命放射性核種の作製?非密封放射性同位元素の安全取扱実習への応用?
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=我々は自然起源放射性物質(NORM)を放射線源とする232Th/212Pbジェネレーターを作製した。ジェネレーターから室温で約500?Bqの高純度の212Pbをミルキングできた。これを用いて32Pを用いた非密封放射性同位元素の安全取扱実習を置き換えることができることを示した。ジェネレーターの作製の容易さ,ミルキング操作の簡便性,212Pb及びその子孫核種の放射性同位元素としての特性から,今回作製した232Th/212Pbジェネレーターは放射線教育に有効に活用できると結論した。
en-copyright=
kn-copyright=
en-aut-name=ImadaYui
en-aut-sei=Imada
en-aut-mei=Yui
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=IsobeMidori
en-aut-sei=Isobe
en-aut-mei=Midori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=TeratoHiroaki
en-aut-sei=Terato
en-aut-mei=Hiroaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=HanafusaTadashi
en-aut-sei=Hanafusa
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
affil-num=1
en-affil=Advanced Science Research Center, Okayama University
kn-affil=
affil-num=2
en-affil=Advanced Science Research Center, Okayama University
kn-affil=
affil-num=3
en-affil=Advanced Science Research Center, Okayama University
kn-affil=
affil-num=4
en-affil=Advanced Science Research Center, Okayama University
kn-affil=
en-keyword=lead-212
kn-keyword=lead-212
en-keyword=radioisotope generator
kn-keyword=radioisotope generator
en-keyword=safe handling training
kn-keyword=safe handling training
en-keyword=unsealed radioisotope
kn-keyword=unsealed radioisotope
END
start-ver=1.4
cd-journal=joma
no-vol=46
cd-vols=
no-issue=1
article-no=
start-page=69
end-page=84
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20251230
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=P53-Armed Oncolytic Virotherapy Promotes the Efficacy of PD1 Blockade in Murine Osteosarcoma Tumors
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Background/Aim: Osteosarcoma (OS) is refractory to immune checkpoint inhibitors targeting programmed cell death 1 (PD1)/PD ligand 1 (PD-L1) due to poor immune response. We previously developed telomerase-specific, replication-competent oncolytic adenoviruses non-armed OBP-301 and P53-armed OBP-702 that exert antitumor efficacy against human OS cells. Recently, we demonstrated that P53-armed OBP-702 induces more profound immunogenic cell death and antitumor immune response against human and murine OS cells than does non-armed OBP-301. In the present study, we assessed the combined efficacy of PD1 blockade and P53-armed OBP-702 against murine OS cells.
Materials and Methods: Three murine OS cell lines (K7M2, NHOS, NHOS-LM4) were used to assess the cytopathic effect of non-armed OBP-301 and P53-armed OBP-702 by XTT assay. Virus-induced immunogenic cell death was assessed by analyzing the levels of extracellular adenosine triphosphate and high-mobility group box protein B1. The expression of PD-L1 and PD-L2 was analyzed by flow cytometry. The malignant potential of NHOS-LM4 cells was analyzed by a migration and invasion assay. An orthotopic NHOS-LM4 tumor model was used to evaluate the antitumor efficacy of combination therapy with P53-armed OBP-702 and anti-PD1.
Results: P53-armed OBP-702 exhibited antitumor potential for the induction of immunogenic cell death, apoptosis, autophagy, and PD-L1/2 upregulation in K7M2 and NHOS cells. NHOS-LM4 cells showed increased migratory and invasive ability compared to NHOS cells. P53-armed OBP-702 significantly suppressed the malignant potential of NHOS-LM4 cells. Combination dosing showed that P53-armed OBP-702 significantly promoted the antitumor effect of PD1 blockade against NHOS-LM4 tumors.
Conclusion: Our results suggest that P53-armed OBP-702 is a promising agent for improving the antitumor effect of PD1 blockade in treating invasive OS.
en-copyright=
kn-copyright=
en-aut-name=KUREMIHO
en-aut-sei=KURE
en-aut-mei=MIHO
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=TAZAWAHIROSHI
en-aut-sei=TAZAWA
en-aut-mei=HIROSHI
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=DEMIYAKOJI
en-aut-sei=DEMIYA
en-aut-mei=KOJI
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=KONDOHIROYA
en-aut-sei=KONDO
en-aut-mei=HIROYA
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=MOCHIZUKIYUSUKE
en-aut-sei=MOCHIZUKI
en-aut-mei=YUSUKE
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=KOMATSUBARATADASHI
en-aut-sei=KOMATSUBARA
en-aut-mei=TADASHI
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=YOSHIDAAKI
en-aut-sei=YOSHIDA
en-aut-mei=AKI
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=UOTANIKOJI
en-aut-sei=UOTANI
en-aut-mei=KOJI
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=HASEIJOE
en-aut-sei=HASEI
en-aut-mei=JOE
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=FUJIWARATOMOHIRO
en-aut-sei=FUJIWARA
en-aut-mei=TOMOHIRO
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=KUNISADATOSHIYUKI
en-aut-sei=KUNISADA
en-aut-mei=TOSHIYUKI
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
en-aut-name=URATAYASUO
en-aut-sei=URATA
en-aut-mei=YASUO
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=
en-aut-name=KAGAWASHUNSUKE
en-aut-sei=KAGAWA
en-aut-mei=SHUNSUKE
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=
en-aut-name=OZAKITOSHIFUMI
en-aut-sei=OZAKI
en-aut-mei=TOSHIFUMI
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=
en-aut-name=FUJIWARATOSHIYOSHI
en-aut-sei=FUJIWARA
en-aut-mei=TOSHIYOSHI
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=
affil-num=1
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=2
en-affil=Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=3
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=4
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=5
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=6
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=7
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=8
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=9
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=10
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=11
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=12
en-affil=Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=13
en-affil=Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=14
en-affil=Department of Orthopaedic Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
affil-num=15
en-affil=Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=
en-keyword=Osteosarcoma
kn-keyword=Osteosarcoma
en-keyword=oncolytic adenovirus
kn-keyword=oncolytic adenovirus
en-keyword=P53
kn-keyword=P53
en-keyword=immunogenic cell death
kn-keyword=immunogenic cell death
en-keyword=PD1
kn-keyword=PD1
END
start-ver=1.4
cd-journal=joma
no-vol=82
cd-vols=
no-issue=2
article-no=
start-page=26-1566
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2026
dt-pub=2026
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=放射線治療装置の回転座標系誤差が軸外targetの照射精度に及ぼす影響とTG142のトレランスの評価
en-subtitle=
kn-subtitle=
en-abstract=Purpose: The aim of this study was to quantitatively evaluate the impact of gantry, collimator, and couch rotational errors in a linear accelerator on the irradiation accuracy of off-isocenter targets, and to assess the validity of the rotational error tolerance (±1.0°) specified in American Association of Physicists in Medicine TG142. Methods: Using an Elekta linear accelerator (Elekta, Stockholm, Sweden) and the MultiMet-WL QA phantom (Sun Nuclear, Melbourne, FL, USA), an off-isocenter Winston?Lutz test was performed on six targets. In addition to baseline measurements, six conditions were evaluated by intentionally introducing rotational errors of +0.5° and +1.0° in the collimator, gantry, and couch. The vector distance (S value) between the field center and the target center, as well as positional deviations in each direction (gantry-target: GT, left-right: LR, anterior-posterior: AP), were analyzed. Results: Targets located farther from the isocenter exhibited more significant positional deviations. The collimator rotation had the greatest impact; at 7 cm from the isocenter, even a 0.5° error resulted in a maximum S value of 1.24 mm. Couch rotation had the next largest effect, while gantry rotation had relatively smaller effects, likely because most targets were located near the gantry’s rotational axis. The rotational errors mainly caused geometric deviations with direction-dependent positional shifts. Conclusion: The effects of the collimator and couch were substantial, with positional deviations exceeding 1 mm even for a 0.5° rotation error. The influence of the gantry was relatively small and dependent on the target configuration. For irradiation of off-axis targets, the TG142 tolerance of ±1.0° should be regarded as a minimum standard that must be strictly observed regardless of the type of linear accelerator. However, depending on the target arrangement, clinically adequate margins may not be ensured. These findings suggest the necessity of applying stricter criteria according to target configuration and emphasize the importance of regular quality assurance.
kn-abstract=【目的】放射線治療装置の回転座標系の誤差が軸外targetの照射精度に及ぼす影響を定量的に評価し,TG142における回転座標系誤差(±1.0°)のトレランスの妥当性を検討する.【方法】Elekta社製放射線治療装置(Elekta, Stockholm, Sweden)とMultiMet-WL QAファントム(Sun Nuclear, Melbourne, FL, USA)を用いて,6個のtargetに対してoff isocenterのWinston?Lutz test(WL test)を実施した.Baselineの測定に加え,意図的にcollimator,gantry,couchに+0.5°, +1.0°回転誤差を加えた6条件で測定を行い,照射野中心とtarget中心のベクトル距離(S値)および各方向(gantry-target: GT, left-right: LR, anterior-posterior: AP)の位置ずれを解析した.【結果】Isocenterからの距離が大きいtargetほど位置ずれが顕著であった.特にcollimator回転誤差の影響が最も大きく,isocenterから7?cm離れたtargetでは0.5°の回転誤差でもS値が最大1.24?mmに達した.次に影響が大きかったのはcouch回転であり,gantry回転はtargetの配置が回転軸に近いものが多く相対的に影響が少なかった.回転座標系の誤差は幾何学的誤差の影響が強く,位置ずれに方向依存性があった.【結語】Collimatorやcouchの影響が大きく,0.5°の誤差でも1?mm以上の位置ずれが生じることがあった.Gantryの影響はtargetの配置依存があり,相対的に小さかった.軸外targetの照射において,TG142の±1.0°のトレランスは放射線治療装置の種類にかかわらず最低限遵守するべき基準であり,targetの配置次第では臨床的に十分なマージンを保証できない可能性が示された.Target配置に応じたより厳格な基準と定期的quality assurance(QA)の重要性が示唆された.
en-copyright=
kn-copyright=
en-aut-name=NakayamaTakahiro
en-aut-sei=Nakayama
en-aut-mei=Takahiro
kn-aut-name=中山貴裕
kn-aut-sei=中山
kn-aut-mei=貴裕
aut-affil-num=1
ORCID=
en-aut-name=TanabeYoshinori
en-aut-sei=Tanabe
en-aut-mei=Yoshinori
kn-aut-name=田辺悦章
kn-aut-sei=田辺
kn-aut-mei=悦章
aut-affil-num=2
ORCID=
en-aut-name=FujiiYasushi
en-aut-sei=Fujii
en-aut-mei=Yasushi
kn-aut-name=藤井康志
kn-aut-sei=藤井
kn-aut-mei=康志
aut-affil-num=3
ORCID=
affil-num=1
en-affil=Department of Radiology, Public Mutual Aid Association Chugoku Central Hospital
kn-affil=公立学校共済組合中国中央病院放射線科
affil-num=2
en-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
kn-affil=岡山大学学術研究院保健学域放射線技術科学専攻
affil-num=3
en-affil=Department of Radiology, Public Mutual Aid Association Chugoku Central Hospital
kn-affil=公立学校共済組合中国中央病院放射線科
en-keyword=off-isocenter Winston?Lutz test
kn-keyword=off-isocenter Winston?Lutz test
en-keyword=rotation error
kn-keyword=rotation error
en-keyword=off-axis targets
kn-keyword=off-axis targets
en-keyword=Elekta
kn-keyword=Elekta
en-keyword=TG142
kn-keyword=TG142
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20251124
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Evaluation of the small-field output factor in eclipse modeling methods using representative beam and measured data with averaged ionization chamber and diode detector measurements
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Beam modeling for radiotherapy treatment planning systems (RTPS) can be performed using representative beam data (RBD) or direct measurements. However, RBD typically excludes output factor (OPF) measurements for fields smaller than 3 × 3 cm2. The Eclipse treatment planning system addresses this limitation by incorporating measured OPF data for fields as small as 1 × 1 cm2. Although existing studies have primarily examined the accuracy of small-field OPFs for plastic scintillator detectors, studies directly comparing the OPF values obtained through RBD modeling with and without OPF measurements for small field sizes are limited. Therefore, this study proposes a novel measurement approach using data averaged from an ion chamber and diode detector for small-field dosimetry to provide critical insights into the integration of OPFs for these small field sizes in RBD-based beam modeling. We systematically evaluated the impact of small-field OPF measurements on beam modeling accuracy by comparing three distinct approaches: (1) RBD-based modeling without small-field OPF data, (2) RBD-based modeling incorporating measured small-field OPF data, and (3) modeling based solely on measured data, with and without the inclusion of 1 × 1 cm2 field sizes. In addition, we compared OPF values obtained from a W2 plastic scintillator detector with the averaged OPF values from a PinPoint 3D ion chamber and EDGE diode detector across multiple beam energies and flattening filter-free (FFF) configurations. Our analysis included field sizes ranging from 1 × 1 cm2 to 40 × 40 cm2. The results demonstrated that for square fields, OPF calculation differences between RBD modeling with and without measured data were < 1.5%, < 4.5%, and < 4.5% at 1 × 1 cm2, and < 0.5%, < 1.5%, and < 1.5% at 2? × ?2 cm2, respectively. The RBD group exhibited a trend in which the OPF difference increased with the expansion of the irradiation field size. Notably, the most significant variations between modeling approaches occurred along the upper jaw expansion direction in rectangular fields. This suggests that a thorough evaluation is necessary for modeling results with an OPF??? 1 × 1 cm2. This study highlights the advantages and disadvantages of beam modeling using measured OPF and RBD, providing valuable insights for future facilities that rely solely on RBD for beam modeling.
en-copyright=
kn-copyright=
en-aut-name=NishiokaKunio
en-aut-sei=Nishioka
en-aut-mei=Kunio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=KuniiYuki
en-aut-sei=Kunii
en-aut-mei=Yuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=TanabeYoshinori
en-aut-sei=Tanabe
en-aut-mei=Yoshinori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=SakamotoYuichi
en-aut-sei=Sakamoto
en-aut-mei=Yuichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=NakamotoAkira
en-aut-sei=Nakamoto
en-aut-mei=Akira
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=TakahashiShotaro
en-aut-sei=Takahashi
en-aut-mei=Shotaro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
affil-num=1
en-affil=Department of Radiology, Tokuyama Central Hospital
kn-affil=
affil-num=2
en-affil=Department of Radiology, Tokuyama Central Hospital
kn-affil=
affil-num=3
en-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=4
en-affil=Department of Radiology, Tokuyama Central Hospital
kn-affil=
affil-num=5
en-affil=Department of Radiology, Tokuyama Central Hospital
kn-affil=
affil-num=6
en-affil=Department of Radiology, Tokuyama Central Hospital
kn-affil=
en-keyword=Beam modeling
kn-keyword=Beam modeling
en-keyword=Plastic scintillator detector
kn-keyword=Plastic scintillator detector
en-keyword=Small irradiation field
kn-keyword=Small irradiation field
en-keyword=Output factor
kn-keyword=Output factor
END
start-ver=1.4
cd-journal=joma
no-vol=56
cd-vols=
no-issue=1
article-no=
start-page=64
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250527
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Evaluating a discretized data acquisition method for couch modeling to streamline the commissioning process of radiological instruments
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Background The commissioning of radiotherapy treatment planning system (RTPS) involves many time-consuming tests to maintain consistency between actual and planned dose. As the number of new technologies and peripheral devices increases year by year, there is a need for time-efficient and accurate commissioning of radiation therapy equipment. Couch modeling is one type of commissioning, and there are no recommended values for CT due to differences in equipment calibration between facilities. This study evaluated the optimal electron density (ED) for the couch using discretized gantry angles.
Results All discrete-angle groups showed a high correlation between the surface ED and dose difference between the actual and planned doses (|r|>?0.9). AcurosXB did not demonstrate a significant correlation between dose differences and each energy. For a small number of discretized gantry groups, the optimal couch modeling results revealed several combinations of surface and interior ED with the same score. Upon adding all couch thickness scores, all energy scores, and both algorithm scores, the optimal surface and interior EDs with the highest score across all couch thicknesses were 0.4 and 0.07, respectively.
Conclusions The optimal couch surface ED dose difference trend was identified, and the effectiveness indicated using the dose difference score from discrete-angle couch modeling. Using this method, couch modeling can be evaluated in a highly precise and quick manner, which helps in the commissioning of complicated linear accelerator and radiological treatment plans.
en-copyright=
kn-copyright=
en-aut-name=TomimotoSyouta
en-aut-sei=Tomimoto
en-aut-mei=Syouta
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=SaekiYusuke
en-aut-sei=Saeki
en-aut-mei=Yusuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=MotodaOkihiro
en-aut-sei=Motoda
en-aut-mei=Okihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=TanakaMasato
en-aut-sei=Tanaka
en-aut-mei=Masato
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=TsumotoSyouki
en-aut-sei=Tsumoto
en-aut-mei=Syouki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=NishikawaHana
en-aut-sei=Nishikawa
en-aut-mei=Hana
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=MiyashimaYuki
en-aut-sei=Miyashima
en-aut-mei=Yuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=HiguchiMakiko
en-aut-sei=Higuchi
en-aut-mei=Makiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=TaniTadashi
en-aut-sei=Tani
en-aut-mei=Tadashi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=KatsuiKuniaki
en-aut-sei=Katsui
en-aut-mei=Kuniaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=TanabeYoshinori
en-aut-sei=Tanabe
en-aut-mei=Yoshinori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
affil-num=1
en-affil=Department of Radiological Technology, Faculty of Medicine, Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=2
en-affil=Department of Radiological Technology, Kawasaki Medical School Hospital
kn-affil=
affil-num=3
en-affil=Department of Radiological Technology, Kawasaki Medical School Hospital
kn-affil=
affil-num=4
en-affil=Department of Radiological Technology, Kawasaki Medical School Hospital
kn-affil=
affil-num=5
en-affil=Department of Radiological Technology, Faculty of Medicine, Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=6
en-affil=Department of Radiological Technology, Faculty of Medicine, Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=7
en-affil=Department of Radiological Technology, Kawasaki Medical School Hospital
kn-affil=
affil-num=8
en-affil=Department of Radiological Technology, Kawasaki Medical School Hospital
kn-affil=
affil-num=9
en-affil=Department of Radiological Technology, Kawasaki Medical School Hospital
kn-affil=
affil-num=10
en-affil=Department of Radiology, Kawasaki Medical School
kn-affil=
affil-num=11
en-affil=Department of Radiological Technology, Faculty of Medicine, Graduate School of Health Sciences, Okayama University
kn-affil=
en-keyword=Couch modeling
kn-keyword=Couch modeling
en-keyword=Commissioning
kn-keyword=Commissioning
en-keyword=Attenuation of couch
kn-keyword=Attenuation of couch
en-keyword=Linear accelerator
kn-keyword=Linear accelerator
en-keyword=Radiotherapy planning system
kn-keyword=Radiotherapy planning system
END
start-ver=1.4
cd-journal=joma
no-vol=15
cd-vols=
no-issue=1
article-no=
start-page=27502
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250728
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Autoantibody spark response predicts treatment outcome in patients receiving chemoradiation followed by durvalumab therapy
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The PACIFIC regimen, comprising chemoradiotherapy (CRT) followed by maintenance with the immune checkpoint inhibitor (ICI) durvalumab, has become the standard of care for patients with unresectable non-small cell lung cancer (NSCLC). Although ICI is used to prevent recurrence by targeting residual microtumors, biomarkers capable of monitoring immune activity during this phase remain lacking. Here, we evaluated whether temporal changes in serum autoantibody levels can predict treatment efficacy. This retrospective study included 20 patients with unresectable stage II or III NSCLC who received the PACIFIC regimen. Serum autoantibodies against 130 antigens were quantified before CRT, after CRT, and two weeks after the first ICI dose. The primary outcome was progression-free survival (PFS), and its association with autoantibody dynamics was examined. We observed an immediate and strong autoantibody response (spark response [SR]) after ICI initiation in patients with favorable treatment outcomes. Patients with SR and programmed death ligand 1 (PD-L1) expression???50% showed better PFS (two-year PFS; 72.9% vs. 18.2%, p?=?0.0021). These findings suggest that serial monitoring of serum autoantibodies can provide a noninvasive approach to assess immune activity and predict treatment outcomes in patients receiving CRT or ICI therapy.
en-copyright=
kn-copyright=
en-aut-name=MoriTakeru
en-aut-sei=Mori
en-aut-mei=Takeru
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=KitagawaMio
en-aut-sei=Kitagawa
en-aut-mei=Mio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=HasegawaTomokazu
en-aut-sei=Hasegawa
en-aut-mei=Tomokazu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=SomeyaMasanori
en-aut-sei=Someya
en-aut-mei=Masanori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=TsuchiyaTakaaki
en-aut-sei=Tsuchiya
en-aut-mei=Takaaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=GochoToshio
en-aut-sei=Gocho
en-aut-mei=Toshio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=HonjoTomoko
en-aut-sei=Honjo
en-aut-mei=Tomoko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=DateMirei
en-aut-sei=Date
en-aut-mei=Mirei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=MoriiMariko
en-aut-sei=Morii
en-aut-mei=Mariko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=MiyamotoAi
en-aut-sei=Miyamoto
en-aut-mei=Ai
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=FutamiJunichiro
en-aut-sei=Futami
en-aut-mei=Junichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
affil-num=1
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
affil-num=2
en-affil=Department of Radiology, Sapporo Medical University School of Medicine
kn-affil=
affil-num=3
en-affil=Department of Radiology, Sapporo Medical University School of Medicine
kn-affil=
affil-num=4
en-affil=Department of Radiology, Sapporo Medical University School of Medicine
kn-affil=
affil-num=5
en-affil=Department of Radiology, Sapporo Medical University School of Medicine
kn-affil=
affil-num=6
en-affil=Department of Radiology, Sapporo Medical University School of Medicine
kn-affil=
affil-num=7
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
affil-num=8
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
affil-num=9
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
affil-num=10
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
affil-num=11
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=
en-keyword=Autoantibodies
kn-keyword=Autoantibodies
en-keyword=PACIFIC regimen
kn-keyword=PACIFIC regimen
en-keyword=ICIs
kn-keyword=ICIs
en-keyword=Immune monitoring
kn-keyword=Immune monitoring
END
start-ver=1.4
cd-journal=joma
no-vol=26
cd-vols=
no-issue=15
article-no=
start-page=7275
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250728
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Acquired Radioresistance Through Adaptive Evolution with Gamma Radiation as Selection Pressure: Increased Expression and Induction of Anti-Stress Genes
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Elucidating the mechanisms of radioresistance in highly radiotolerant organisms can provide valuable insights into the adaptation and evolution of organisms. However, research has been limited on many naturally occurring radioresistant organisms due to a lack of information regarding their genetic and biochemical characteristics and the difficulty of handling them experimentally. To address this, we conducted an experiment on adaptive evolution using gamma radiation as the selection pressure to generate evolved Escherichia coli with gamma radiation resistance approximately one order of magnitude greater than that of wild-type E. coli. Gene expressions in all wild-type and evolved radioresistant E. coli in the presence or absence of gamma irradiation were analyzed and compared using RNA sequencing. Under steady-state conditions, the genes involved in survival, cell recovery, DNA repair, and response following stress exposure were upregulated in evolved E. coli compared with those in wild-type E. coli. Furthermore, the evolved E. coli induced these genes more efficiently following gamma irradiation and greater DNA repair activity than that in the wild-type E. coli. Our results indicate that an increased steady-state expression of various anti-stress genes, including DNA repair-related genes, and their highly efficient induction under irradiation are responsible for the remarkable radioresistance of evolved E. coli.
en-copyright=
kn-copyright=
en-aut-name=SaitoTakeshi
en-aut-sei=Saito
en-aut-mei=Takeshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=TeratoHiroaki
en-aut-sei=Terato
en-aut-mei=Hiroaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
affil-num=1
en-affil=Division of Radiation Life Science, Institute for Integrated Radiation and Nuclear Science, Kyoto University
kn-affil=
affil-num=2
en-affil=Department of Radiation Research, Advanced Science Research Center, Okayama University
kn-affil=
en-keyword=radioresistant bacteria
kn-keyword=radioresistant bacteria
en-keyword=Escherichia coli
kn-keyword=Escherichia coli
en-keyword=adaptive evolution
kn-keyword=adaptive evolution
en-keyword=gene expression changes
kn-keyword=gene expression changes
en-keyword=anti-stress genes
kn-keyword=anti-stress genes
en-keyword=DNA repair
kn-keyword=DNA repair
en-keyword=cell recovery
kn-keyword=cell recovery
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250723
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Impact of differences in computed tomography value-electron density/physical density conversion tables on calculate dose in low-density areas
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In radiotherapy treatment planning, the extrapolation of computed tomography (CT) values for low-density areas without known materials may differ between CT scanners, resulting in different calculated doses. We evaluated the differences in the percentage depth dose (PDD) calculated using eight CT scanners. Heterogeneous virtual phantoms were created using LN-300 lung and ??900 HU. For the two types of virtual phantoms, the PDD on the central axis was calculated using five energies, two irradiation field sizes, and two calculation algorithms (the anisotropic analytical algorithm and Acuros XB). For the LN-300 lung, the maximum CT value difference between the eight CT scanners was 51 HU for an electron density (ED) of 0.29 and 8.8 HU for an extrapolated ED of 0.05. The LN-300 lung CT values showed little variation in the CT-ED/physical density data among CT scanners. The difference in the point depth for the PDD in the LN-300 lung between the CT scanners was?0.5% for all energies and calculation algorithms. Using Acuros XB, the PDD at ? 900 HU had a maximum difference between facilities of?>?5%, and the dose difference corresponding to an LN-300 lung CT value difference of?>?20 HU was?>?1% at a field size of 2?×?2 cm2. The study findings suggest that the calculated dose of low-density regions without known materials in the CT-ED conversion table introduces a risk of dose differences between facilities because of the calibration of the CT values, even when the same CT-ED phantom radiation treatment planning and treatment devices are used.
en-copyright=
kn-copyright=
en-aut-name=NomuraMia
en-aut-sei=Nomura
en-aut-mei=Mia
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=GotoShunsuke
en-aut-sei=Goto
en-aut-mei=Shunsuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=YoshiokaMizuki
en-aut-sei=Yoshioka
en-aut-mei=Mizuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=KatoYuiko
en-aut-sei=Kato
en-aut-mei=Yuiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=TsunodaAyaka
en-aut-sei=Tsunoda
en-aut-mei=Ayaka
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=NishiokaKunio
en-aut-sei=Nishioka
en-aut-mei=Kunio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=TanabeYoshinori
en-aut-sei=Tanabe
en-aut-mei=Yoshinori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
affil-num=1
en-affil=Faculty of Health Sciences, Department of Radiological Technology, Okayama University Medical School, Okayama University
kn-affil=
affil-num=2
en-affil=Graduate School of Health Sciences, Department of Radiological Technology, Okayama University
kn-affil=
affil-num=3
en-affil=Faculty of Health Sciences, Department of Radiological Technology, Okayama University Medical School, Okayama University
kn-affil=
affil-num=4
en-affil=Faculty of Health Sciences, Department of Radiological Technology, Okayama University Medical School, Okayama University
kn-affil=
affil-num=5
en-affil=Faculty of Health Sciences, Department of Radiological Technology, Okayama University Medical School, Okayama University
kn-affil=
affil-num=6
en-affil=Department of Radiology, Tokuyama Central Hospital
kn-affil=
affil-num=7
en-affil=Faculty of Medicine, Graduate School of Health Sciences, Okayama University
kn-affil=
en-keyword=Computed tomography
kn-keyword=Computed tomography
en-keyword=Dose calculation
kn-keyword=Dose calculation
en-keyword=Inter-facility variation
kn-keyword=Inter-facility variation
en-keyword=Low-density regions
kn-keyword=Low-density regions
en-keyword=Percentage depth dose
kn-keyword=Percentage depth dose
en-keyword=Radiation therapy planning system
kn-keyword=Radiation therapy planning system
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=20250325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=肺腫瘍に対する定位放射線治療におけるターゲット設定の不確かさに関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=NAKANISHIDaiki
en-aut-sei=NAKANISHI
en-aut-mei=Daiki
kn-aut-name=中西大樹
kn-aut-sei=中西
kn-aut-mei=大樹
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学大学院ヘルスシステム統合科学研究科
END
start-ver=1.4
cd-journal=joma
no-vol=50
cd-vols=
no-issue=1
article-no=
start-page=100
end-page=107
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2025
dt-pub=202501
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Introduction:Photon-counting computed tomography (CT) is equipped with an adaptive iterative reconstruction method called quantum iterative reconstruction (QIR), which allows the intensity to be changed during image reconstruction. It is known that the reconstruction conditions of CT images affect the analysis results when performing radiomic analysis. The aim of this study is to investigate the effect of QIR intensity on image quality and radiomic analysis of renal cell carcinoma (RCC).
Materials and Methods:The QIR intensities were selected as off, 2 and 4. The image quality evaluation items considered were task-based transfer function (TTF), noise power spectrum (NPS), and low-contrast object specific contrast-to-noise ratio (CNRLO). The influence on radiomic analysis was assessed using the discrimination accuracy of clear cell RCC.
Results:For image quality evaluation, TTF and NPS values were lower and CNRLO values were higher with increasing QIR intensity; for radiomic analysis, sensitivity, specificity, and accuracy were higher with increasing QIR intensity. Principal component analysis and receiver operating characteristics analysis also showed higher values with increasing QIR intensity.
Conclusion:It was confirmed that the intensity of the QIR intensity affects both the image quality and the radiomic analysis.
en-copyright=
kn-copyright=
en-aut-name=OhataMiyu
en-aut-sei=Ohata
en-aut-mei=Miyu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=FukuiRyohei
en-aut-sei=Fukui
en-aut-mei=Ryohei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=MorimitsuYusuke
en-aut-sei=Morimitsu
en-aut-mei=Yusuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=KobayashiDaichi
en-aut-sei=Kobayashi
en-aut-mei=Daichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=YamauchiTakatsugu
en-aut-sei=Yamauchi
en-aut-mei=Takatsugu
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=AkagiNoriaki
en-aut-sei=Akagi
en-aut-mei=Noriaki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=HondaMitsugi
en-aut-sei=Honda
en-aut-mei=Mitsugi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=HayashiAiko
en-aut-sei=Hayashi
en-aut-mei=Aiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=HasegawaKoshi
en-aut-sei=Hasegawa
en-aut-mei=Koshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=KidaKatsuhiro
en-aut-sei=Kida
en-aut-mei=Katsuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=GotoSachiko
en-aut-sei=Goto
en-aut-mei=Sachiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
en-aut-name=HirakiTakao
en-aut-sei=Hiraki
en-aut-mei=Takao
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=
affil-num=1
en-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=2
en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University
kn-affil=
affil-num=3
en-affil=Division of Radiological Technology, Okayama University Hospital
kn-affil=
affil-num=4
en-affil=Division of Radiological Technology, Okayama University Hospital
kn-affil=
affil-num=5
en-affil=Division of Radiological Technology, Okayama University Hospital
kn-affil=
affil-num=6
en-affil=Division of Radiological Technology, Okayama University Hospital
kn-affil=
affil-num=7
en-affil=Division of Radiological Technology, Okayama University Hospital
kn-affil=
affil-num=8
en-affil=Department of Radiology, Hiroshima University Hospital
kn-affil=
affil-num=9
en-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=10
en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University
kn-affil=
affil-num=11
en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University
kn-affil=
affil-num=12
en-affil=Department of Radiology, Faculty of Medicine, Dentistry and Pharmaceutical, Okayama University
kn-affil=
en-keyword=Image quality
kn-keyword=Image quality
en-keyword=photon-counting computed tomography
kn-keyword=photon-counting computed tomography
en-keyword=quantum iterative reconstruction
kn-keyword=quantum iterative reconstruction
en-keyword=radiomics
kn-keyword=radiomics
en-keyword=renal cell carcinoma
kn-keyword=renal cell carcinoma
END
start-ver=1.4
cd-journal=joma
no-vol=49
cd-vols=
no-issue=4
article-no=
start-page=563
end-page=567
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=202410
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Backside Irradiation of Ultraviolet-A for Correcting Nonuniformity Error of Gafchromic XR-QA2 Films
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Purpose: Radiochromic film is used for quality assurance and quality control of X-ray equipment in the diagnostic radiology. In addition, three-dimensional dose distribution of computed tomography (CT) is measured. To correct the nonuniformity and uncertainty of radiochromic films for dose measurement of CT, the films are preirradiated ultraviolet (UV)-A rays. There is a difference in the UV protection strength of radiochromic films. A concern exists about the effects of the UV-A irradiation intensity. We thus irradiated with UV-A rays from the backsides of the films to assess if backside irradiation was possible. Materials and Methods: Gafchromic XR-QA2 and RTQA2 were used in this study. The UV-A rays were simultaneously irradiated on the front and backsides of each film for 12 h. The yellow layer of each film was scanned and imaged. The average pixel values ± standard deviations (SDs) were compared. In the statistical analysis, a paired t-test was performed. To compare, the active-layer densities engendered by the UV-A rays. Calibration curve was created with 48 h of preirradiation of UV-A. Results: The mean pixel values ± SD for Gafchromic XR-QA2 on the front and backsides were 130.776 ± 0.812 and 81.015 ± 1.128, respectively. On the other hand, the mean pixel values ± SD for Gafchromic RTQA2 on the front and backsides were 62.299 ± 1.077 and 133.761 ± 1.365, respectively. The statistical results of the paired t-test were significantly different (P < 0.01) between both films. Fitting equation of the calibration curve is shown below. y = -390.47 ± 200 + (443.45 ± 10x80).5068 ± 0.0434. Conclusion: Based on the relationship between the sensitivity of the active layer to UV-A rays and the strength of UV protection on the surface, we concluded that backside irradiation is recommended for Gafchromic XR-QA2, and frontside irradiation is recommended for Gafchromic RTQA2.
en-copyright=
kn-copyright=
en-aut-name=TankiNobuyoshi
en-aut-sei=Tanki
en-aut-mei=Nobuyoshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=GotoSachiko
en-aut-sei=Goto
en-aut-mei=Sachiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=KatsudaToshizo
en-aut-sei=Katsuda
en-aut-mei=Toshizo
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=GotandaRumi
en-aut-sei=Gotanda
en-aut-mei=Rumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=GotandaTatsuhiro
en-aut-sei=Gotanda
en-aut-mei=Tatsuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=KuwanoTadao
en-aut-sei=Kuwano
en-aut-mei=Tadao
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
affil-num=1
en-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
kn-affil=
affil-num=2
en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University
kn-affil=
affil-num=3
en-affil=Department of Medical Radiation Technology, Shizuoka College of Medicalcare Science
kn-affil=
affil-num=4
en-affil=Department of Radiological Technology, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare
kn-affil=
affil-num=5
en-affil=Department of Radiological Technology, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare
kn-affil=
affil-num=6
en-affil=Department of Radiology, Osaka Center for Cancer and Cardiovascular Diseases Prevention
kn-affil=
en-keyword=Backside irradiation
kn-keyword=Backside irradiation
en-keyword=computed tomography
kn-keyword=computed tomography
en-keyword=reflective type radiochromic film
kn-keyword=reflective type radiochromic film
en-keyword=ultraviolet radiation
kn-keyword=ultraviolet radiation
END
start-ver=1.4
cd-journal=joma
no-vol=136
cd-vols=
no-issue=3
article-no=
start-page=120
end-page=126
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20241202
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Effects of parity on the associations between evacuation and psychological distress and cardiovascular disease among women after the Great East Japan Earthquake : A cross-sectional study of the Fukushima Health Management Survey
kn-title=東日本大震災後の女性における出産歴が避難と精神的苦痛や循環器疾患との関連に及ぼす影響:福島県「県民健康調査」を用いた横断研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= Introduction : Women are more likely to be physically, mentally, and socially vulnerable after disasters because of the physical, socioeconomical, and lifestyle-related factors that are often related to their parity. Here, we analyzed the effects of women's parity on the association between evacuation and psychological distress, trauma reactions, and cardiovascular disease (CVD).
Participants and Methods : The participants were residents living in 13 municipalities in the evacuation zone of Japan's Fukushima Prefecture after the March 11, 2011 Great East Japan Earthquake who responded to the Fukushima Health Management Survey in FY2012. A total of 30,709 women aged 40-90 years were included in the analyses. We performed a logistic regression analysis to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) adjusted for CVD risk factors.
Results : A multivariate analysis revealed that among the parous women (n = 19,608), evacuation was associated with psychological distress (adjusted OR 1.30, 95%CI : 1.17-1.44), trauma reactions (OR 1.22, 95%CI : 1.11-1.35), and heart disease (OR 1.14, 95%CI : 1.03-1.26) compared to the non-evacuation status. Among the nulliparous women (n = 1,794), there was no association between the evacuation and any outcomes.
Conclusion : The evacuation of individuals after the Great East Japan Earthquake was associated with psychological distress, trauma reactions, and heart disease, especially among parous women.
en-copyright=
kn-copyright=
en-aut-name=YasukawaSumiyo
en-aut-sei=Yasukawa
en-aut-mei=Sumiyo
kn-aut-name=安川純代
kn-aut-sei=安川
kn-aut-mei=純代
aut-affil-num=1
ORCID=
en-aut-name=EguchiEri
en-aut-sei=Eguchi
en-aut-mei=Eri
kn-aut-name=江口依里
kn-aut-sei=江口
kn-aut-mei=依里
aut-affil-num=2
ORCID=
en-aut-name=OhiraTetsuya
en-aut-sei=Ohira
en-aut-mei=Tetsuya
kn-aut-name=大平哲也
kn-aut-sei=大平
kn-aut-mei=哲也
aut-affil-num=3
ORCID=
en-aut-name=HayashiFumikazu
en-aut-sei=Hayashi
en-aut-mei=Fumikazu
kn-aut-name=林史和
kn-aut-sei=林
kn-aut-mei=史和
aut-affil-num=4
ORCID=
en-aut-name=SakaiAkira
en-aut-sei=Sakai
en-aut-mei=Akira
kn-aut-name=坂井晃
kn-aut-sei=坂井
kn-aut-mei=晃
aut-affil-num=5
ORCID=
en-aut-name=ShimabukuroMichio
en-aut-sei=Shimabukuro
en-aut-mei=Michio
kn-aut-name=島袋充生
kn-aut-sei=島袋
kn-aut-mei=充生
aut-affil-num=6
ORCID=
en-aut-name=FujimoriKeiya
en-aut-sei=Fujimori
en-aut-mei=Keiya
kn-aut-name=藤森敬也
kn-aut-sei=藤森
kn-aut-mei=敬也
aut-affil-num=7
ORCID=
en-aut-name=MiuraItaru
en-aut-sei=Miura
en-aut-mei=Itaru
kn-aut-name=三浦至
kn-aut-sei=三浦
kn-aut-mei=至
aut-affil-num=8
ORCID=
en-aut-name=YabeHirooki
en-aut-sei=Yabe
en-aut-mei=Hirooki
kn-aut-name=矢部博興
kn-aut-sei=矢部
kn-aut-mei=博興
aut-affil-num=9
ORCID=
en-aut-name=MaedaMasaharu
en-aut-sei=Maeda
en-aut-mei=Masaharu
kn-aut-name=前田正治
kn-aut-sei=前田
kn-aut-mei=正治
aut-affil-num=10
ORCID=
en-aut-name=YasumuraSeiji
en-aut-sei=Yasumura
en-aut-mei=Seiji
kn-aut-name=安村誠司
kn-aut-sei=安村
kn-aut-mei=誠司
aut-affil-num=11
ORCID=
affil-num=1
en-affil=Department of Nursing, Faculty of Health Sciences, Okayama University
kn-affil=岡山大学学術研究院保健学域 看護学
affil-num=2
en-affil=Department of Epidemiology, School of Medicine, Fukushima Medical University
kn-affil=福島県立医科大学医学部 疫学
affil-num=3
en-affil=Department of Epidemiology, School of Medicine, Fukushima Medical University
kn-affil=福島県立医科大学医学部 疫学
affil-num=4
en-affil=Department of Epidemiology, School of Medicine, Fukushima Medical University
kn-affil=福島県立医科大学医学部 疫学
affil-num=5
en-affil=Radiation Medical Science Center, Fukushima Medical University
kn-affil=福島県立医科大学放射線医学県民健康管理センター
affil-num=6
en-affil=Radiation Medical Science Center, Fukushima Medical University
kn-affil=福島県立医科大学放射線医学県民健康管理センター
affil-num=7
en-affil=Radiation Medical Science Center, Fukushima Medical University
kn-affil=福島県立医科大学放射線医学県民健康管理センター
affil-num=8
en-affil=Radiation Medical Science Center, Fukushima Medical University
kn-affil=福島県立医科大学放射線医学県民健康管理センター
affil-num=9
en-affil=Radiation Medical Science Center, Fukushima Medical University
kn-affil=福島県立医科大学放射線医学県民健康管理センター
affil-num=10
en-affil=Radiation Medical Science Center, Fukushima Medical University
kn-affil=福島県立医科大学放射線医学県民健康管理センター
affil-num=11
en-affil=Radiation Medical Science Center, Fukushima Medical University
kn-affil=福島県立医科大学放射線医学県民健康管理センター
en-keyword=東日本大震災(the Great East Japan Earthquake)
kn-keyword=東日本大震災(the Great East Japan Earthquake)
en-keyword=大規模災害(large disaster)
kn-keyword=大規模災害(large disaster)
en-keyword=出産歴(parity)
kn-keyword=出産歴(parity)
en-keyword=精神的苦痛(psychological distress)
kn-keyword=精神的苦痛(psychological distress)
en-keyword=循環器疾患(cardiovascular disease)
kn-keyword=循環器疾患(cardiovascular disease)
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240925
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=放射線治療品質管理の重要性と標準化に向けた実践に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=TANIMOTOYuki
en-aut-sei=TANIMOTO
en-aut-mei=Yuki
kn-aut-name=谷本祐樹
kn-aut-sei=谷本
kn-aut-mei=祐樹
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学大学院ヘルスシステム統合科学研究科
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240925
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=軟骨無形成症の新生児および乳幼児における骨格成長の放射線学的特徴
kn-title=Radiological characteristics of skeletal growth in neonates and infants with achondroplasia
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=MIYAHARADaisuke
en-aut-sei=MIYAHARA
en-aut-mei=Daisuke
kn-aut-name=宮原大輔
kn-aut-sei=宮原
kn-aut-mei=大輔
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END
start-ver=1.4
cd-journal=joma
no-vol=78
cd-vols=
no-issue=3
article-no=
start-page=215
end-page=225
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=202406
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Assessment of a New Elbow Joint Positioning Method Using Area Detector Computed Tomography
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We propose a sitting position that achieves both high image quality and a reduced radiation dose in elbow joint imaging by area detector computed tomography (ADCT), and we compared it with the ‘superman’ and supine positions. The volumetric CT dose index (CTDIvol) for the sitting, superman, and supine positions were 2.7, 8.0, and 20.0 mGy and the dose length products (DLPs) were 43.4, 204.7, and 584.8 mGy ? cm, respectively. In the task-based transfer function (TTF), the highest value was obtained for the sitting position in both bone and soft tissue images. The noise power spectrum (NPS) of bone images showed that the superman position had the lowest value up to approx. 1.1 cycles/mm or lower, whereas the sitting position had the lowest value when the NPS was greater than approx. 1.1 cycles/mm. The overall image quality in an observer study resulted in the following median Likert scores for Readers 1 and 2: 5.0 and 5.0 for the sitting position, 4.0 and 3.5 for the superman position, and 4.0 and 2.0 for the supine position. These results indicate that our proposed sitting position with ADCT of the elbow joint can provide superior image quality and allow lower radiation doses compared to the superman and supine positions.
en-copyright=
kn-copyright=
en-aut-name=AkagawaTakuya
en-aut-sei=Akagawa
en-aut-mei=Takuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=FukuiRyohei
en-aut-sei=Fukui
en-aut-mei=Ryohei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=KidaKatsuhiro
en-aut-sei=Kida
en-aut-mei=Katsuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=MatsuuraRyutaro
en-aut-sei=Matsuura
en-aut-mei=Ryutaro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=ShimadaMakoto
en-aut-sei=Shimada
en-aut-mei=Makoto
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=KinoshitaMitsuhiro
en-aut-sei=Kinoshita
en-aut-mei=Mitsuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=AkagawaYoko
en-aut-sei=Akagawa
en-aut-mei=Yoko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=GotoSachiko
en-aut-sei=Goto
en-aut-mei=Sachiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
affil-num=1
en-affil=Department of Radiological Technology, Tokushima Red Cross Hospital
kn-affil=
affil-num=2
en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University
kn-affil=
affil-num=3
en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University
kn-affil=
affil-num=4
en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University
kn-affil=
affil-num=5
en-affil=Department of Radiology, Osaka International Cancer Institute
kn-affil=
affil-num=6
en-affil=Department of Radiology, Tokushima Red Cross Hospital
kn-affil=
affil-num=7
en-affil=Department of Radiology, Tokushima Red Cross Hospital
kn-affil=
affil-num=8
en-affil=Department of Radiological Technology, Faculty of Health Sciences, Okayama University
kn-affil=
en-keyword=area detector computed tomography
kn-keyword=area detector computed tomography
en-keyword=elbow joint
kn-keyword=elbow joint
en-keyword=sitting position
kn-keyword=sitting position
en-keyword=dose reduction
kn-keyword=dose reduction
en-keyword=image quality assessment
kn-keyword=image quality assessment
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2024
dt-pub=20240325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=p53を搭載した腫瘍溶解ウイルス療法はBCL-xL発現抑制を介して軟部肉腫の放射線感受性を改善する
kn-title=p53-Armed Oncolytic Virotherapy Improves Radiosensitivity in Soft-Tissue Sarcoma by Suppressing BCL-xL Expression
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=KOMATSUBARATadashi
en-aut-sei=KOMATSUBARA
en-aut-mei=Tadashi
kn-aut-name=小松原将
kn-aut-sei=小松原
kn-aut-mei=将
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230925
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=悪性神経膠腫に対する強度変調陽子線治療と強度変調回転放射線治療の線量分布比較に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=MIYATAJunya
en-aut-sei=MIYATA
en-aut-mei=Junya
kn-aut-name=宮田潤也
kn-aut-sei=宮田
kn-aut-mei=潤也
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama University
kn-affil=岡山大学大学院ヘルスシステム統合科学研究科
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2005
dt-pub=20050930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=岡山県における環境放射能・放射線
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=鑛山宗利
kn-aut-sei=鑛山
kn-aut-mei=宗利
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=20230324
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=RNA編集は、結腸直腸癌においてオキサリプラチン・放射線療法同時投与中にネオアンチゲンの生成増強を促進する
kn-title=RNA editing facilitates the enhanced production of neoantigens during the simultaneous administration of oxaliplatin and radiotherapy in colorectal cancer
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=KOMATSUYasuhiro
en-aut-sei=KOMATSU
en-aut-mei=Yasuhiro
kn-aut-name=小松泰浩
kn-aut-sei=小松
kn-aut-mei=泰浩
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END
start-ver=1.4
cd-journal=joma
no-vol=134
cd-vols=
no-issue=3
article-no=
start-page=145
end-page=151
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=20221201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Non-vascular interventional radiology for lung cancer
kn-title=肺癌に対する非血管系IVR
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=HirakiTakao
en-aut-sei=Hiraki
en-aut-mei=Takao
kn-aut-name=平木隆夫
kn-aut-sei=平木
kn-aut-mei=隆夫
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Department of Radiology, Faculty of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学学術研究院医歯薬学域 放射線医学
en-keyword=肺癌(lung cancer)
kn-keyword=肺癌(lung cancer)
en-keyword=インターベンショナルラジオロジー(interventional radiology)
kn-keyword=インターベンショナルラジオロジー(interventional radiology)
en-keyword=非血管系(non-vascular)
kn-keyword=非血管系(non-vascular)
END
start-ver=1.4
cd-journal=joma
no-vol=28
cd-vols=
no-issue=2
article-no=
start-page=41
end-page=49
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2022
dt-pub=2022
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Interpretation of the official Japanese translation summary of the “MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy” (Updated 2019-2020)
kn-title=「MASCC/ISOO 口腔粘膜障害のマネジメントに関する臨床ガイドライン(2019-2020改訂版)」公式日本語訳概要の解釈について
en-subtitle=
kn-subtitle=
en-abstract=Adverse events frequently occur with chemotherapy, radiation therapy involving the oral cavity, and hematopoietic stem cell transplantation in cancer treatment. The Multinational Association of Supportive Care in Cancer and the International Society for Oral Oncology (MASCC/ISOO) have developed a systematic review methodology and published a updated version of the “MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy” in 2019-2020. In addition, an official Japanese translation of the summary overview was also published. However, because it is an international guideline, some references are made to unapproved drugs or off-label use in Japan. In addition, some parts of the summary outline do not convey the intent derived from the original text. This paper introduces the contents of the revised guideline and details the contents of the summary overview of the guideline with the above-mentioned problems in mind.
kn-abstract=がん治療における化学療法、口腔を照射野に含む放射線療法、および造血幹細胞移植では、有害事象として口腔粘膜障害がしばしば発生する。がん支持療法の国際学会であるMultinational Association of Supportive Care in Cancer および International Society for Oral Oncology (MASCC/ISOO)は、システマティックレビューの手法により、2019年から2020年にかけて、「MASCC/ISOO 口腔粘膜障害のマネジメントに関する臨床ガイドライン」の改訂版を発表した。さらに、総括の概要について、日本語の公式翻訳版も発表された。しかし、国際的なガイドラインであるが故に、日本での非承認薬あるいは適応外使用について言及されている内容が多い。また、総括の概要で、原文に由来する意図が伝わりにくい箇所がある。本稿では、改訂されたガイドラインの内容について紹介するとともに、上述した問題点を念頭に、ガイドラインの総括の概要に記載された内容について詳述した。
en-copyright=
kn-copyright=
en-aut-name=SOGAYoshihiko
en-aut-sei=SOGA
en-aut-mei=Yoshihiko
kn-aut-name=曽我賢彦
kn-aut-sei=曽我
kn-aut-mei=賢彦
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Division of Hospital Dentistry, Okayama University Hospital
kn-affil=岡山大学病院 医療支援歯科治療部
en-keyword=口腔粘膜障害
kn-keyword=口腔粘膜障害
en-keyword=口腔粘膜炎
kn-keyword=口腔粘膜炎
en-keyword=がん治療
kn-keyword=がん治療
en-keyword=ガイドライン
kn-keyword=ガイドライン
en-keyword=MASCC/ISOO
kn-keyword=MASCC/ISOO
END
start-ver=1.4
cd-journal=joma
no-vol=77
cd-vols=
no-issue=1
article-no=
start-page=45
end-page=55
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2023
dt-pub=202302
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Image Quality Assessment of Deep Learning Image Reconstruction in Torso Computed Tomography Using Tube Current Modulation
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Novel deep learning image reconstruction (DLIR) reportedly changes the image quality characteristics based on object contrast and image noise. In clinical practice, computed tomography image noise is usually controlled by tube current modulation (TCM) to accommodate changes in object size. This study aimed to evaluate the image quality characteristics of DLIR for different object sizes when the in-plane noise was controlled by TCM. Images acquisition was performed on a GE Revolution CT system to investigate the impact of the DLIR algorithm compared to the standard reconstructions of filtered-back projection (FBP) and hybrid iterative reconstruction (hybrid-IR). The image quality assessment was performed using phantom images, and an observer study was conducted using clinical cases. The image quality assessment confirmed the excellent noise- reduction performance of DLIR, despite variations due to phantom size. Similarly, in the observer study, DLIR received high evaluations regardless of the body parts imaged. We evaluated a novel DLIR algorithm by replicating clinical behaviors. Consequently, DLIR exhibited higher image quality than those of FBP and hybrid-IR in both phantom and observer studies, albeit the value depended on the reconstruction strength, and proved itself capable of providing stable image quality in clinical use.
en-copyright=
kn-copyright=
en-aut-name=TakeuchiKazuhiro
en-aut-sei=Takeuchi
en-aut-mei=Kazuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=IdeYasuhiro
en-aut-sei=Ide
en-aut-mei=Yasuhiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=MoriYuichiro
en-aut-sei=Mori
en-aut-mei=Yuichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=UeharaYusuke
en-aut-sei=Uehara
en-aut-mei=Yusuke
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=SukeishiHiroshi
en-aut-sei=Sukeishi
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=GotoSachiko
en-aut-sei=Goto
en-aut-mei=Sachiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
affil-num=1
en-affil=Department of Radiology, Kagawa University Hospital
kn-affil=
affil-num=2
en-affil=Department of Radiology, Kagawa University Hospital
kn-affil=
affil-num=3
en-affil=Department of Radiology, Kagawa University Hospital
kn-affil=
affil-num=4
en-affil=Department of Radiology, Kagawa University Hospital
kn-affil=
affil-num=5
en-affil=Department of Radiology, Kagawa University Hospital
kn-affil=
affil-num=6
en-affil=Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
kn-affil=
en-keyword=computed tomography
kn-keyword=computed tomography
en-keyword=deep learning
kn-keyword=deep learning
en-keyword=image reconstruction
kn-keyword=image reconstruction
en-keyword=tube current modulation
kn-keyword=tube current modulation
en-keyword=object size
kn-keyword=object size
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210924
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=腫瘍融解ウイルス療法はMCL1発現を抑制することで軟部肉腫の放射線感受性を増強する
kn-title=Oncolytic virotherapy promotes radiosensitivity in soft tissue sarcoma by suppressing anti-apoptotic MCL1 expression
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=OmoriToshinori
en-aut-sei=Omori
en-aut-mei=Toshinori
kn-aut-name=大森敏規
kn-aut-sei=大森
kn-aut-mei=敏規
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END
start-ver=1.4
cd-journal=joma
no-vol=133
cd-vols=
no-issue=2
article-no=
start-page=127
end-page=128
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210802
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Telemedicine in radiology
kn-title=遠隔治療 放射線科編
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=MatsuiYusuke
en-aut-sei=Matsui
en-aut-mei=Yusuke
kn-aut-name=松井裕輔
kn-aut-sei=松井
kn-aut-mei=裕輔
aut-affil-num=1
ORCID=
en-aut-name=KanazawaSusumu
en-aut-sei=Kanazawa
en-aut-mei=Susumu
kn-aut-name=金澤右
kn-aut-sei=金澤
kn-aut-mei=右
aut-affil-num=2
ORCID=
affil-num=1
en-affil=Department of Radiology, Okayama University Hospital
kn-affil=岡山大学病院 放射線科
affil-num=2
en-affil=Department of Radiology, Okayama University Hospital
kn-affil=川崎医科大学 総合放射線医学
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2021
dt-pub=20210325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=高齢者寛骨臼骨折に対する骨接合:marginal impactionもしくはroof impactionに関する疫学的及び臨床放射線学的研究
kn-title=Osteosynthesis for Geriatric Acetabular Fractures: An Epidemiological and Clinico-Radiological Study Related to Marginal or Roof Impaction
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=InoueMadoka
en-aut-sei=Inoue
en-aut-mei=Madoka
kn-aut-name=井上円加
kn-aut-sei=井上
kn-aut-mei=円加
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2019
dt-pub=20190325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=化学放射線併用治療中に測定されたGPS(Glasgow prognostic score)は子宮頚癌において重要な予後因子となる
kn-title=The Glasgow Prognostic Score Determined During Concurrent Chemoradiotherapy Is an Independent Predictor of Survival for Cervical Cancer
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=NishidaTakeshi
en-aut-sei=Nishida
en-aut-mei=Takeshi
kn-aut-name=西田傑
kn-aut-sei=西田
kn-aut-mei=傑
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20181227
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=線量体積因子は非小細胞肺癌に対する導入同時併用化学放射線療法おける術後の放射線肺臓炎を予測する
kn-title=Dose-Volume Parameters Predict Radiation Pneumonitis after Surgery with Induction Concurrent Chemoradiotherapy for Non-small Cell Lung Cancer
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=OgataTakeshi
en-aut-sei=Ogata
en-aut-mei=Takeshi
kn-aut-name=尾形毅
kn-aut-sei=尾形
kn-aut-mei=毅
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
kn-affil=岡山大学大学院医歯薬学総合研究科
END
start-ver=1.4
cd-journal=joma
no-vol=130
cd-vols=
no-issue=2
article-no=
start-page=51
end-page=53
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20180801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The 2017 Incentive Award of the Okayama Medical Association in General Medical Science (2017 Yuuki Prize)
kn-title=平成29年度岡山医学会賞 総合研究奨励賞(結城賞)
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=HirakiTakao
en-aut-sei=Hiraki
en-aut-mei=Takao
kn-aut-name=平木隆夫
kn-aut-sei=平木
kn-aut-mei=隆夫
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2018
dt-pub=20180323
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=冠動脈疾患患者の雑音低減技術による放射線量低下時の画質の検討
kn-title=Image Quality of the Coronary Angiography with Noise Reduction Technology to Decrease the Radiation Dose
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=KumashiroMasayuki
en-aut-sei=Kumashiro
en-aut-mei=Masayuki
kn-aut-name=熊代正行
kn-aut-sei=熊代
kn-aut-mei=正行
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Graduate School of Health Sciences, Okayama University
kn-affil=岡山大学大学院保健学研究科
END
start-ver=1.4
cd-journal=joma
no-vol=129
cd-vols=
no-issue=2
article-no=
start-page=147
end-page=148
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2017
dt-pub=20170801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The 46th Annual Meeting of the Japanese Society of Interventional Radiology
kn-title=第46回日本インターベンショナルラジオロジー (IVR) 学会総会開催報告
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=KanazawaSusumu
en-aut-sei=Kanazawa
en-aut-mei=Susumu
kn-aut-name=金澤右
kn-aut-sei=金澤
kn-aut-mei=右
aut-affil-num=1
ORCID=
affil-num=1
en-affil=Department of Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学
END
start-ver=1.4
cd-journal=joma
no-vol=126
cd-vols=
no-issue=3
article-no=
start-page=227
end-page=230
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=20141201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Molecular target therapies in rheumatic diseases
kn-title=リウマチ性疾患における分子標的治療
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=WakabayashiHiroshi
en-aut-sei=Wakabayashi
en-aut-mei=Hiroshi
kn-aut-name=若林宏
kn-aut-sei=若林
kn-aut-mei=宏
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 腎・免疫・内分泌代謝内科学
en-keyword=リウマチ性疾患
kn-keyword=リウマチ性疾患
en-keyword=自己免疫疾患
kn-keyword=自己免疫疾患
en-keyword=生物学的製剤
kn-keyword=生物学的製剤
en-keyword=分子標的薬
kn-keyword=分子標的薬
END
start-ver=1.4
cd-journal=joma
no-vol=126
cd-vols=
no-issue=3
article-no=
start-page=209
end-page=215
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=20141201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Hospital and clinic cooperation for the treatment of rheumatoid arthritis in Okayama Prefecture, Japan
kn-title=岡山県下のクリニック・診療所におけるリウマチ診療・病診連携の実態に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Objective: To survey the current status and problems of cooperation between clinics and hospitals in Okayama Prefecture, Japan for the treatment of rheumatoid arthritis (RA).
Methods: We distributed a questionnaire to 300 of the 983 Okayama Prefecture clinics that had either an internal medicine or orthopedic surgery department, from December 2013 to February 2014. The questionnaire covered practice pattern for RA treatment in clinics, current status of the hospital and clinic cooperation, and acceptance of the biologic therapy.
Results: One hundred clinics responded to the questionnaire. Seventy percent of the clinics reported making referrals to rheumatologists before the initiation of RA treatment, and half of the other 30% of the clinics administered methotrexate as the first-line treatment for RA by their own decision. Sixty-six clinics cooperated with flagship hospitals, conducting medical and laboratory examinations, providing prescriptions, and treating common diseases of patients. These clinics expected the cooperating rheumatologists to follow-up patients every 3 to 6 months and to make the diagnosis, make decisions regarding RA treatment changes, and perform surgery. Seventy-one percent of the clinics responded that cooperation with a hospital is possible even for patients who are administered biologics. As reasons for no cooperation with the flagship hospitals, clinics noted the lack of information about rheumatologists in the area and recent trends in the management of RA.
Conclusion: The current study reported, for the first time, the actual conditions of management of RA in clinics, as well as future problems of hospital and clinic cooperation in Okayama Prefecture.
en-copyright=
kn-copyright=
en-aut-name=SadaKen-ei
en-aut-sei=Sada
en-aut-mei=Ken-ei
kn-aut-name=佐田憲映
kn-aut-sei=佐田
kn-aut-mei=憲映
aut-affil-num=1
ORCID=
en-aut-name=NishidaKeiichiro
en-aut-sei=Nishida
en-aut-mei=Keiichiro
kn-aut-name=西田圭一郎
kn-aut-sei=西田
kn-aut-mei=圭一郎
aut-affil-num=2
ORCID=
en-aut-name=YamanakaTakao
en-aut-sei=Yamanaka
en-aut-mei=Takao
kn-aut-name=山中隆夫
kn-aut-sei=山中
kn-aut-mei=隆夫
aut-affil-num=3
ORCID=
en-aut-name=MisakiKenta
en-aut-sei=Misaki
en-aut-mei=Kenta
kn-aut-name=三崎健太
kn-aut-sei=三崎
kn-aut-mei=健太
aut-affil-num=4
ORCID=
en-aut-name=WakabayashiHiroshi
en-aut-sei=Wakabayashi
en-aut-mei=Hiroshi
kn-aut-name=若林宏
kn-aut-sei=若林
kn-aut-mei=宏
aut-affil-num=5
ORCID=
en-aut-name=ShinodaJunko
en-aut-sei=Shinoda
en-aut-mei=Junko
kn-aut-name=篠田潤子
kn-aut-sei=篠田
kn-aut-mei=潤子
aut-affil-num=6
ORCID=
en-aut-name=TakagiToru
en-aut-sei=Takagi
en-aut-mei=Toru
kn-aut-name=木徹
kn-aut-sei=木
kn-aut-mei=徹
aut-affil-num=7
ORCID=
en-aut-name=YanoRyusuke
en-aut-sei=Yano
en-aut-mei=Ryusuke
kn-aut-name=矢野隆介
kn-aut-sei=矢野
kn-aut-mei=隆介
aut-affil-num=8
ORCID=
en-aut-name=NakamuraAkihiko
en-aut-sei=Nakamura
en-aut-mei=Akihiko
kn-aut-name=中村明彦
kn-aut-sei=中村
kn-aut-mei=明彦
aut-affil-num=9
ORCID=
en-aut-name=NanbaYoshifumi
en-aut-sei=Nanba
en-aut-mei=Yoshifumi
kn-aut-name=難波良文
kn-aut-sei=難波
kn-aut-mei=良文
aut-affil-num=10
ORCID=
en-aut-name=MoritaYoshitaka
en-aut-sei=Morita
en-aut-mei=Yoshitaka
kn-aut-name=守田吉孝
kn-aut-sei=守田
kn-aut-mei=吉孝
aut-affil-num=11
ORCID=
en-aut-name=KoyamaYoshinobu
en-aut-sei=Koyama
en-aut-mei=Yoshinobu
kn-aut-name=小山芳伸
kn-aut-sei=小山
kn-aut-mei=芳伸
aut-affil-num=12
ORCID=
en-aut-name=YamamotoKeiji
en-aut-sei=Yamamoto
en-aut-mei=Keiji
kn-aut-name=山本惠嗣
kn-aut-sei=山本
kn-aut-mei=惠嗣
aut-affil-num=13
ORCID=
en-aut-name=EzawaKazuhiko
en-aut-sei=Ezawa
en-aut-mei=Kazuhiko
kn-aut-name=江澤和彦
kn-aut-sei=江澤
kn-aut-mei=和彦
aut-affil-num=14
ORCID=
en-aut-name=OtaYusuke
en-aut-sei=Ota
en-aut-mei=Yusuke
kn-aut-name=太田裕介
kn-aut-sei=太田
kn-aut-mei=裕介
aut-affil-num=15
ORCID=
en-aut-name=YoshiharaYoshiki
en-aut-sei=Yoshihara
en-aut-mei=Yoshiki
kn-aut-name=吉原由樹
kn-aut-sei=吉原
kn-aut-mei=由樹
aut-affil-num=16
ORCID=
en-aut-name=MiyoshiShinya
en-aut-sei=Miyoshi
en-aut-mei=Shinya
kn-aut-name=三好信也
kn-aut-sei=三好
kn-aut-mei=信也
aut-affil-num=17
ORCID=
en-aut-name=NatsumedaMasamitsu
en-aut-sei=Natsumeda
en-aut-mei=Masamitsu
kn-aut-name=棗田将光
kn-aut-sei=棗田
kn-aut-mei=将光
aut-affil-num=18
ORCID=
en-aut-name=UsuiMasaaki
en-aut-sei=Usui
en-aut-mei=Masaaki
kn-aut-name=臼井正明
kn-aut-sei=臼井
kn-aut-mei=正明
aut-affil-num=19
ORCID=
en-aut-name=YoshinagaYasuhiko
en-aut-sei=Yoshinaga
en-aut-mei=Yasuhiko
kn-aut-name=吉永泰彦
kn-aut-sei=吉永
kn-aut-mei=泰彦
aut-affil-num=20
ORCID=
en-aut-name=HayashiTakashi
en-aut-sei=Hayashi
en-aut-mei=Takashi
kn-aut-name=林充
kn-aut-sei=林
kn-aut-mei=充
aut-affil-num=21
ORCID=
en-aut-name=YamamuraMasahiro
en-aut-sei=Yamamura
en-aut-mei=Masahiro
kn-aut-name=山村昌弘
kn-aut-sei=山村
kn-aut-mei=昌弘
aut-affil-num=22
ORCID=
en-aut-name=HashizumeHiroyuki
en-aut-sei=Hashizume
en-aut-mei=Hiroyuki
kn-aut-name=橋詰博行
kn-aut-sei=橋詰
kn-aut-mei=博行
aut-affil-num=23
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 腎・免疫・内分泌代謝内科学
affil-num=2
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 人体構成学
affil-num=3
en-affil=
kn-affil=南岡山医療センター リウマチ科
affil-num=4
en-affil=
kn-affil=倉敷中央病院 内分泌代謝・リウマチ内科
affil-num=5
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 腎・免疫・内分泌代謝内科学
affil-num=6
en-affil=
kn-affil=岡山労災病院 整形外科
affil-num=7
en-affil=
kn-affil=岡山赤十字病院 整形外科
affil-num=8
en-affil=
kn-affil=矢野内科医院
affil-num=9
en-affil=
kn-affil=おさふねクリニック
affil-num=10
en-affil=
kn-affil=川崎医科大学附属病院 整形外科
affil-num=11
en-affil=
kn-affil=川崎医科大学附属病院 リウマチ・膠原病科
affil-num=12
en-affil=
kn-affil=岡山赤十字病院 膠原病リウマチ内科
affil-num=13
en-affil=
kn-affil=山本整形外科医院
affil-num=14
en-affil=
kn-affil=倉敷スイートホスピタル 内科
affil-num=15
en-affil=
kn-affil=香川労災病院 整形外科
affil-num=16
en-affil=
kn-affil=倉敷成人病センター 整形外科
affil-num=17
en-affil=
kn-affil=倉敷成人病センター 整形外科
affil-num=18
en-affil=
kn-affil=倉敷スイートホスピタル 内科
affil-num=19
en-affil=
kn-affil=岡山市民病院 整形外科
affil-num=20
en-affil=
kn-affil=倉敷成人病センター リウマチ膠原病内科
affil-num=21
en-affil=
kn-affil=佐用中央病院 整形外科
affil-num=22
en-affil=
kn-affil=岡山済生会総合病院 内科
affil-num=23
en-affil=
kn-affil=笠岡第一病院 整形外科
en-keyword=病診連携(hospital and clinic cooperation)
kn-keyword=病診連携(hospital and clinic cooperation)
en-keyword=関節リウマチ(rheumatoid arthritis)
kn-keyword=関節リウマチ(rheumatoid arthritis)
en-keyword=生物学的製剤(biologics)
kn-keyword=生物学的製剤(biologics)
en-keyword=メトトレキサート(methotrexate)
kn-keyword=メトトレキサート(methotrexate)
END
start-ver=1.4
cd-journal=joma
no-vol=126
cd-vols=
no-issue=2
article-no=
start-page=171
end-page=172
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=20140801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=放射線第一病院
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=木本眞
kn-aut-sei=木本
kn-aut-mei=眞
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=
END
start-ver=1.4
cd-journal=joma
no-vol=126
cd-vols=
no-issue=2
article-no=
start-page=103
end-page=107
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=20140801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Induction therapy followed by surgery for non small-cell lung cancer
kn-title=非小細胞肺癌に対する術前治療後外科切除療法
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=ToyookaShinichi
en-aut-sei=Toyooka
en-aut-mei=Shinichi
kn-aut-name=豊岡伸一
kn-aut-sei=豊岡
kn-aut-mei=伸一
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 臨床遺伝子医療学
en-keyword=非小細胞肺癌
kn-keyword=非小細胞肺癌
en-keyword=導入療法
kn-keyword=導入療法
en-keyword=放射線化学療法
kn-keyword=放射線化学療法
en-keyword=外科切除
kn-keyword=外科切除
END
start-ver=1.4
cd-journal=joma
no-vol=30
cd-vols=
no-issue=
article-no=
start-page=3
end-page=6
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=201404
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The role of autophagy of early embryonic development in mice
kn-title=マウス初期胚発生におけるオートファジーの役割
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=After fertilization, maternal products which are stored during oogenesis are rapidly degraded and newly zygotic
products are synthesized in most animals. This transition, known as an oocyte-to-embryo transition, is critical step for
further embryonic development. Considering that the process occurs quickly, bulk degradation system could be highly
activated to eliminate maternal products and recycle them to synthesize newly products. We have demonstrated that
autophagy, which is cytoplasmic bulk degradation system mediated by the lysosome, is highly induced after fertilization,
and autophagy-deficient embryo dies before implantation, suggesting that autophagy is essential for preimplantaion
embryonic development. Our recent studies also revealed that lysosomal size and number changes during the embryonic
development. Here we will briefly review the autophagy, and discuss the function of autophagy and lysosome in early
mouse embryogenesis.
en-copyright=
kn-copyright=
en-aut-name=TsukamotoSatoshi
en-aut-sei=Tsukamoto
en-aut-mei=Satoshi
kn-aut-name=塚本智史
kn-aut-sei=塚本
kn-aut-mei=智史
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=独立行政法人 放射線医学総合研究所・研究基盤センター・生物研究推進課
END
start-ver=1.4
cd-journal=joma
no-vol=27
cd-vols=
no-issue=6
article-no=
start-page=1046
end-page=1056
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1992
dt-pub=199206
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=免疫組織染色およびフローサイトメトリーによる放射線照射後の細胞増殖能の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=玉田隆
kn-aut-sei=玉田
kn-aut-mei=隆
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学
END
start-ver=1.4
cd-journal=joma
no-vol=35
cd-vols=
no-issue=
article-no=
start-page=2
end-page=7
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=201402
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=放射性セシウムの土壌中での挙動と農作物への移行
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=内田滋夫
kn-aut-sei=内田
kn-aut-mei=滋夫
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=(独)放射線医学総合研究所
END
start-ver=1.4
cd-journal=joma
no-vol=126
cd-vols=
no-issue=1
article-no=
start-page=11
end-page=15
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2014
dt-pub=20140401
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A preoperative SUVmax greater than the ADCmin of the primary tumour : A predictor of disease recurrence and survival in patients with endometrial cancer
kn-title=PET/CT SUVmaxは子宮体癌の予後不良因子になりうる
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=NakamuraKeiichiro
en-aut-sei=Nakamura
en-aut-mei=Keiichiro
kn-aut-name=中村圭一郎
kn-aut-sei=中村
kn-aut-mei=圭一郎
aut-affil-num=1
ORCID=
en-aut-name=JojaIkuo
en-aut-sei=Joja
en-aut-mei=Ikuo
kn-aut-name=上者郁夫
kn-aut-sei=上者
kn-aut-mei=郁夫
aut-affil-num=2
ORCID=
en-aut-name=FukushimaChikako
en-aut-sei=Fukushima
en-aut-mei=Chikako
kn-aut-name=福島千加子
kn-aut-sei=福島
kn-aut-mei=千加子
aut-affil-num=3
ORCID=
en-aut-name=HarumaTomoko
en-aut-sei=Haruma
en-aut-mei=Tomoko
kn-aut-name=春間朋子
kn-aut-sei=春間
kn-aut-mei=朋子
aut-affil-num=4
ORCID=
en-aut-name=HayashiChiaki
en-aut-sei=Hayashi
en-aut-mei=Chiaki
kn-aut-name=林千晶
kn-aut-sei=林
kn-aut-mei=千晶
aut-affil-num=5
ORCID=
en-aut-name=KusumotoTomoyuki
en-aut-sei=Kusumoto
en-aut-mei=Tomoyuki
kn-aut-name=楠本知行
kn-aut-sei=楠本
kn-aut-mei=知行
aut-affil-num=6
ORCID=
en-aut-name=SekiNoriko
en-aut-sei=Seki
en-aut-mei=Noriko
kn-aut-name=関典子
kn-aut-sei=関
kn-aut-mei=典子
aut-affil-num=7
ORCID=
en-aut-name=HongoAtsushi
en-aut-sei=Hongo
en-aut-mei=Atsushi
kn-aut-name=本郷淳司
kn-aut-sei=本郷
kn-aut-mei=淳司
aut-affil-num=8
ORCID=
en-aut-name=HiramatsuYuji
en-aut-sei=Hiramatsu
en-aut-mei=Yuji
kn-aut-name=平松祐司
kn-aut-sei=平松
kn-aut-mei=祐司
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 産科婦人科学
affil-num=2
en-affil=
kn-affil=岡山大学大学院保健学研究科 放射線技術科学
affil-num=3
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 産科婦人科学
affil-num=4
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 産科婦人科学
affil-num=5
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 産科婦人科学
affil-num=6
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 産科婦人科学
affil-num=7
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 産科婦人科学
affil-num=8
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 産科婦人科学
affil-num=9
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 産科婦人科学
en-keyword=endometrial cancer
kn-keyword=endometrial cancer
en-keyword=SUVmax
kn-keyword=SUVmax
en-keyword=PET/CT
kn-keyword=PET/CT
en-keyword=predictor of poor prognosis
kn-keyword=predictor of poor prognosis
END
start-ver=1.4
cd-journal=joma
no-vol=28
cd-vols=
no-issue=1
article-no=
start-page=37
end-page=42
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2009
dt-pub=200906
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Achievements and Next Themes of Dental Section of Perioperative Management Center in Okayama University Hospital at 5 Months after Establishment
kn-title=岡山大学病院周術期管理センター(歯科部門)設立後5ヵ月間の活動内容および今後の展開
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=YamanakaReiko
en-aut-sei=Yamanaka
en-aut-mei=Reiko
kn-aut-name=山中玲子
kn-aut-sei=山中
kn-aut-mei=玲子
aut-affil-num=1
ORCID=
en-aut-name=SogaYoshihiko
en-aut-sei=Soga
en-aut-mei=Yoshihiko
kn-aut-name=曽我賢彦
kn-aut-sei=曽我
kn-aut-mei=賢彦
aut-affil-num=2
ORCID=
en-aut-name=NawachiKumiko
en-aut-sei=Nawachi
en-aut-mei=Kumiko
kn-aut-name=縄稚久美子
kn-aut-sei=縄稚
kn-aut-mei=久美子
aut-affil-num=3
ORCID=
en-aut-name=YanagiYoshinobu
en-aut-sei=Yanagi
en-aut-mei=Yoshinobu
kn-aut-name=柳文修
kn-aut-sei=柳
kn-aut-mei=文修
aut-affil-num=4
ORCID=
en-aut-name=KodamaNaoki
en-aut-sei=Kodama
en-aut-mei=Naoki
kn-aut-name=兒玉直紀
kn-aut-sei=兒玉
kn-aut-mei=直紀
aut-affil-num=5
ORCID=
en-aut-name=NakataTakashi
en-aut-sei=Nakata
en-aut-mei=Takashi
kn-aut-name=中田貴
kn-aut-sei=中田
kn-aut-mei=貴
aut-affil-num=6
ORCID=
en-aut-name=MiuraRumi
en-aut-sei=Miura
en-aut-mei=Rumi
kn-aut-name=三浦留美
kn-aut-sei=三浦
kn-aut-mei=留美
aut-affil-num=7
ORCID=
en-aut-name=HagawaMisao
en-aut-sei=Hagawa
en-aut-mei=Misao
kn-aut-name=羽川操
kn-aut-sei=羽川
kn-aut-mei=操
aut-affil-num=8
ORCID=
en-aut-name=TakeuchiTetsuo
en-aut-sei=Takeuchi
en-aut-mei=Tetsuo
kn-aut-name=竹内哲男
kn-aut-sei=竹内
kn-aut-mei=哲男
aut-affil-num=9
ORCID=
en-aut-name=YamaneMieko
en-aut-sei=Yamane
en-aut-mei=Mieko
kn-aut-name=山根美榮子
kn-aut-sei=山根
kn-aut-mei=美榮子
aut-affil-num=10
ORCID=
en-aut-name=MoritaManabu
en-aut-sei=Morita
en-aut-mei=Manabu
kn-aut-name=森田学
kn-aut-sei=森田
kn-aut-mei=学
aut-affil-num=11
ORCID=
en-aut-name=TakashibaShogo
en-aut-sei=Takashiba
en-aut-mei=Shogo
kn-aut-name=高柴正悟
kn-aut-sei=高柴
kn-aut-mei=正悟
aut-affil-num=12
ORCID=
en-aut-name=AsamiJun-ichi
en-aut-sei=Asami
en-aut-mei=Jun-ichi
kn-aut-name=浅海淳一
kn-aut-sei=浅海
kn-aut-mei=淳一
aut-affil-num=13
ORCID=
en-aut-name=MinagiShogo
en-aut-sei=Minagi
en-aut-mei=Shogo
kn-aut-name=皆木省吾
kn-aut-sei=皆木
kn-aut-mei=省吾
aut-affil-num=14
ORCID=
en-aut-name=YoshiyamaMasahiro
en-aut-sei=Yoshiyama
en-aut-mei=Masahiro
kn-aut-name=吉山昌宏
kn-aut-sei=吉山
kn-aut-mei=昌宏
aut-affil-num=15
ORCID=
en-aut-name=ShimonoTsutomu
en-aut-sei=Shimono
en-aut-mei=Tsutomu
kn-aut-name=下野勉
kn-aut-sei=下野
kn-aut-mei=勉
aut-affil-num=16
ORCID=
en-aut-name=KubokiTakuo
en-aut-sei=Kuboki
en-aut-mei=Takuo
kn-aut-name=窪木拓男
kn-aut-sei=窪木
kn-aut-mei=拓男
aut-affil-num=17
ORCID=
en-aut-name=SasakiAkira
en-aut-sei=Sasaki
en-aut-mei=Akira
kn-aut-name=佐々木朗
kn-aut-sei=佐々木
kn-aut-mei=朗
aut-affil-num=18
ORCID=
en-aut-name=MoritaKiyoshi
en-aut-sei=Morita
en-aut-mei=Kiyoshi
kn-aut-name=森田潔
kn-aut-sei=森田
kn-aut-mei=潔
aut-affil-num=19
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学病院周術期管理センター(歯科部門)
affil-num=2
en-affil=
kn-affil=岡山大学病院周術期管理センター(歯科部門)
affil-num=3
en-affil=
kn-affil=岡山大学病院周術期管理センター(歯科部門)
affil-num=4
en-affil=
kn-affil=岡山大学病院周術期管理センター(歯科部門)
affil-num=5
en-affil=
kn-affil=岡山大学病院周術期管理センター(歯科部門)
affil-num=6
en-affil=
kn-affil=岡山大学病院周術期管理センター(歯科部門)
affil-num=7
en-affil=
kn-affil=岡山大学病院周術期管理センター(歯科部門)
affil-num=8
en-affil=
kn-affil=岡山大学病院医療技術部歯科衛生士室
affil-num=9
en-affil=
kn-affil=岡山大学病院医療技術部歯科技工室
affil-num=10
en-affil=
kn-affil=岡山大学病院周術期管理センター(歯科部門)
affil-num=11
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科予防歯科学分野
affil-num=12
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科歯周病態学分野
affil-num=13
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科歯科放射線学分野
affil-num=14
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科咬合・有床義歯補綴学分野
affil-num=15
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科歯科保存修復学分野
affil-num=16
en-affil=
kn-affil=岡山大学病院医療技術部歯科衛生士室
affil-num=17
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科インプラント再生補綴学分野
affil-num=18
en-affil=
kn-affil=岡山大学病院副病院長
affil-num=19
en-affil=
kn-affil=岡山大学病院病院長
END
start-ver=1.4
cd-journal=joma
no-vol=100
cd-vols=
no-issue=11-12
article-no=
start-page=1035
end-page=1043
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1988
dt-pub=1988
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Bronchial artery embolization for hemoptysis using stainless steel coils
kn-title=喀血に対する気管支動脈塞栓術 ―Stainless Steel Coilを用いて―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Four patients with hemoptysis were treated by bronchial artery embolization, using only stainless steel coils 5mm or 3mm in diameter as the embolic material. Immediate control of hemoptysis was achieved in 3 of the 4 patients without any significant complication. Two of these patients are alive without recurrent hemoptysis, one of them 3 months and the other two years one month after the embolization. One of these patient died of renal failure 5 days after embolization. Recurrent hemoptysis occurred in 1 of the 4 patients with incomplete embolization. A second attempt at embolization failed because the coil fell down through the aorta into the iliac artery. The coil was surgically removed under fluoroscopy. Since the stainless steel coil is a non-absorbable embolic material, if carefully used, longer therapeutic results can be achieved for patients with hemoptysis.
en-copyright=
kn-copyright=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=1
ORCID=
en-aut-name=SakamotoKazuhiro
en-aut-sei=Sakamoto
en-aut-mei=Kazuhiro
kn-aut-name=坂本和裕
kn-aut-sei=坂本
kn-aut-mei=和裕
aut-affil-num=2
ORCID=
en-aut-name=MiyamotoTsutomu
en-aut-sei=Miyamoto
en-aut-mei=Tsutomu
kn-aut-name=宮本勉
kn-aut-sei=宮本
kn-aut-mei=勉
aut-affil-num=3
ORCID=
en-aut-name=MatsunoShinsuke
en-aut-sei=Matsuno
en-aut-mei=Shinsuke
kn-aut-name=松野慎介
kn-aut-sei=松野
kn-aut-mei=慎介
aut-affil-num=4
ORCID=
en-aut-name=HosokawaNobuyuki
en-aut-sei=Hosokawa
en-aut-mei=Nobuyuki
kn-aut-name=細川敦之
kn-aut-sei=細川
kn-aut-mei=敦之
aut-affil-num=5
ORCID=
en-aut-name=SeoHiroyuki
en-aut-sei=Seo
en-aut-mei=Hiroyuki
kn-aut-name=瀬尾裕之
kn-aut-sei=瀬尾
kn-aut-mei=裕之
aut-affil-num=6
ORCID=
en-aut-name=KojimaKanji
en-aut-sei=Kojima
en-aut-mei=Kanji
kn-aut-name=児島完治
kn-aut-sei=児島
kn-aut-mei=完治
aut-affil-num=7
ORCID=
en-aut-name=SatohKatashi
en-aut-sei=Satoh
en-aut-mei=Katashi
kn-aut-name=佐藤功
kn-aut-sei=佐藤
kn-aut-mei=功
aut-affil-num=8
ORCID=
en-aut-name=KawasakiYukiko
en-aut-sei=Kawasaki
en-aut-mei=Yukiko
kn-aut-name=川崎幸子
kn-aut-sei=川崎
kn-aut-mei=幸子
aut-affil-num=9
ORCID=
en-aut-name=TakashimaHitoshi
en-aut-sei=Takashima
en-aut-mei=Hitoshi
kn-aut-name=高島均
kn-aut-sei=高島
kn-aut-mei=均
aut-affil-num=10
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=11
ORCID=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=12
ORCID=
en-aut-name=NakamuraKenji
en-aut-sei=Nakamura
en-aut-mei=Kenji
kn-aut-name=中村憲二
kn-aut-sei=中村
kn-aut-mei=憲二
aut-affil-num=13
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=9
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=10
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=11
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=12
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=13
en-affil=
kn-affil=香川医科大学第二外科学教室
en-keyword=喀血
kn-keyword=喀血
en-keyword=気管支動脈
kn-keyword=気管支動脈
en-keyword=気管支動脈塞栓術
kn-keyword=気管支動脈塞栓術
en-keyword=Stainless Steel Coil
kn-keyword=Stainless Steel Coil
END
start-ver=1.4
cd-journal=joma
no-vol=125
cd-vols=
no-issue=3
article-no=
start-page=263
end-page=265
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20131202
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=IVR
kn-title=IVR
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=KanazawaSusumu
en-aut-sei=Kanazawa
en-aut-mei=Susumu
kn-aut-name=金澤右
kn-aut-sei=金澤
kn-aut-mei=右
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学
END
start-ver=1.4
cd-journal=joma
no-vol=125
cd-vols=
no-issue=3
article-no=
start-page=239
end-page=242
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20131202
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of appendiceal diverticulum resected by laparoscopic surgery with preoperative diagnosis of appendiceal tumor
kn-title=虫垂腫瘍と術前診断し腹腔鏡下手術を行った虫垂仮性憩室症の1例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract= Appendiceal diverticulum is rare. We encountered a case of appendiceal diverticulum with chronic appendicitis. A 56-year-old man presented to our hospital with right lower abdominal pain. An abdominal computed tomography (CT) scan showed swelling of the appendix body and the wall thickness of the base of the appendix. Due to the possibility of appendiceal tumor, we performed a laparoscopy-assisted ileocecal resection with lymph node dissection. The appendix had a diverticulum with chronic inflammation, but it did not have a neoplastic lesion.
en-copyright=
kn-copyright=
en-aut-name=NinomiyaTakayuki
en-aut-sei=Ninomiya
en-aut-mei=Takayuki
kn-aut-name=二宮卓之
kn-aut-sei=二宮
kn-aut-mei=卓之
aut-affil-num=1
ORCID=
en-aut-name=OjimaYasutomo
en-aut-sei=Ojima
en-aut-mei=Yasutomo
kn-aut-name=小島康知
kn-aut-sei=小島
kn-aut-mei=康知
aut-affil-num=2
ORCID=
en-aut-name=HaranoMasao
en-aut-sei=Harano
en-aut-mei=Masao
kn-aut-name=原野雅生
kn-aut-sei=原野
kn-aut-mei=雅生
aut-affil-num=3
ORCID=
en-aut-name=OhnoSatoshi
en-aut-sei=Ohno
en-aut-mei=Satoshi
kn-aut-name=大野聡
kn-aut-sei=大野
kn-aut-mei=聡
aut-affil-num=4
ORCID=
en-aut-name=ShiozakiShigehiro
en-aut-sei=Shiozaki
en-aut-mei=Shigehiro
kn-aut-name=塩崎滋弘
kn-aut-sei=塩崎
kn-aut-mei=滋弘
aut-affil-num=5
ORCID=
en-aut-name=NinomiyaMotoki
en-aut-sei=Ninomiya
en-aut-mei=Motoki
kn-aut-name=二宮基樹
kn-aut-sei=二宮
kn-aut-mei=基樹
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=広島市立広島市民病院 外科
affil-num=2
en-affil=
kn-affil=広島市立広島市民病院 外科
affil-num=3
en-affil=
kn-affil=広島市立広島市民病院 外科
affil-num=4
en-affil=
kn-affil=広島市立広島市民病院 外科
affil-num=5
en-affil=
kn-affil=広島市立広島市民病院 外科
affil-num=6
en-affil=
kn-affil=広島市立広島市民病院 外科
en-keyword=虫垂憩室症(appendiceal diverculum)
kn-keyword=虫垂憩室症(appendiceal diverculum)
en-keyword=腹腔鏡手術(laparoscopic surgery)
kn-keyword=腹腔鏡手術(laparoscopic surgery)
en-keyword=虫垂腫瘍(appendiceal tumor)
kn-keyword=虫垂腫瘍(appendiceal tumor)
END
start-ver=1.4
cd-journal=joma
no-vol=144
cd-vols=
no-issue=3
article-no=
start-page=272
end-page=282
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=201209
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Spred-2 deficiency exacerbates acetaminophen-induced hepatotoxicity in mice
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=MAPKs are involved in acetaminophen (APAP)-hepatotoxicity, but the regulatory mechanism remains unknown. Here, we explored the role of Spred-2 that negatively regulates Ras/ERK pathway in APAP-hepatotoxicity. Spred-2 knockout (KO) mice demonstrated exacerbated liver injury, an event that was associated with increased numbers of CD4(+) T, CD8(+) T and NK cells in the liver compared to the control. Levels of CXCL9/CXCL10 that attract and activate these cells were increased in Spred-2 KO-liver. Kupffer cells isolated from Spred-2 KO mice after APAP challenge expressed higher levels of CXCL9/CXCL10 than those from the control. Upon stimulation with APAP or IFN gamma, naive Kupffer cells from Spred-2 KO mice expressed higher levels of CXCL9/CXCL10. NK cell-depletion attenuated APAP-hepatotoxicity with lowered hepatic IFN gamma and decreased numbers of not only NK cells but also CD4(+) T and CD8(+) T cells in the liver. These results suggest that Spred-2 negatively regulates APAP-hepatotoxicity under the control of Kupffer cells and NK cells.
en-copyright=
kn-copyright=
en-aut-name=WakabayashiHiroshi
en-aut-sei=Wakabayashi
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=ItoToshihiro
en-aut-sei=Ito
en-aut-mei=Toshihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=FushimiSoichiro
en-aut-sei=Fushimi
en-aut-mei=Soichiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=NakashimaYuki
en-aut-sei=Nakashima
en-aut-mei=Yuki
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=ItakuraJyunya
en-aut-sei=Itakura
en-aut-mei=Jyunya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=LiuQiuying
en-aut-sei=Liu
en-aut-mei=Qiuying
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=WinMin Min
en-aut-sei=Win
en-aut-mei=Min Min
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=SunCuiming
en-aut-sei=Sun
en-aut-mei=Cuiming
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=ChenCao
en-aut-sei=Chen
en-aut-mei=Cao
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=SatoMiwa
en-aut-sei=Sato
en-aut-mei=Miwa
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
en-aut-name=MinoMegumi
en-aut-sei=Mino
en-aut-mei=Megumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=11
ORCID=
en-aut-name=OginoTetsuya
en-aut-sei=Ogino
en-aut-mei=Tetsuya
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=12
ORCID=
en-aut-name=MakinoHirofumi
en-aut-sei=Makino
en-aut-mei=Hirofumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=13
ORCID=
en-aut-name=YoshimuraAkihiko
en-aut-sei=Yoshimura
en-aut-mei=Akihiko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=14
ORCID=
en-aut-name=MatsukawaAkihiro
en-aut-sei=Matsukawa
en-aut-mei=Akihiro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=15
ORCID=
affil-num=1
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=2
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=3
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=4
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=5
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=6
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=7
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=8
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=9
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=10
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=11
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=12
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
affil-num=13
en-affil=
kn-affil=Okayama Univ, Dept Med & Clin Sci, Grad Sch Med Dent & Pharmaceut Sci
affil-num=14
en-affil=
kn-affil=Keio Univ, Sch Med, Dept Microbiol & Immunol
affil-num=15
en-affil=
kn-affil=Okayama Univ, Dept Pathol & Expt Med, Grad Sch Med Dent & Pharmaceut Sci
en-keyword=Acetaminophen
kn-keyword=Acetaminophen
en-keyword=Hepatotoxicity
kn-keyword=Hepatotoxicity
en-keyword=Liver immunology
kn-keyword=Liver immunology
en-keyword=Signaling pathway
kn-keyword=Signaling pathway
en-keyword=Toxicology
kn-keyword=Toxicology
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2013
dt-pub=20130325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=非小細胞肺癌に対する導入化学放射線療法における予後因子としての癌幹細胞関連マーカー
kn-title=Prognostic impact of cancer stem cell-related markers in non-small cell lung cancer patients treated with induction chemoradiotherapy
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=SienKazuhiko
en-aut-sei=Sien
en-aut-mei=Kazuhiko
kn-aut-name=枝園和彦
kn-aut-sei=枝園
kn-aut-mei=和彦
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学
END
start-ver=1.4
cd-journal=joma
no-vol=28
cd-vols=
no-issue=
article-no=
start-page=15
end-page=26
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2012
dt-pub=201204
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=My reminiscence of experimental animals and animal experimentations
kn-title=実験動物と動物実験について今思うこと
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=NishikawaTetsu
en-aut-sei=Nishikawa
en-aut-mei=Tetsu
kn-aut-name=西川哲
kn-aut-sei=西川
kn-aut-mei=哲
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=(独)放射線医学総合研究所
END
start-ver=1.4
cd-journal=joma
no-vol=59
cd-vols=
no-issue=8
article-no=
start-page=386
end-page=394
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1999
dt-pub=19990725
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=心臓領域における高速3次元MRI撮像法の基礎的・臨床的検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=佐藤修平
kn-aut-sei=佐藤
kn-aut-mei=修平
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学
en-keyword=MP-RAGE
kn-keyword=MP-RAGE
en-keyword=Heart
kn-keyword=Heart
en-keyword=MRI
kn-keyword=MRI
END
start-ver=1.4
cd-journal=joma
no-vol=55
cd-vols=
no-issue=14
article-no=
start-page=929
end-page=938
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1995
dt-pub=199511
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=MR Angiography in Interthoracic Masses:Evaluation of the superior vena cava,its major branches and their relation to the mass
kn-title=胸部腫瘤病変におけるMR angiographyの評価 上大静脈とその分枝ならびに腫瘤との関連性の描出能について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=
en-aut-sei=
en-aut-mei=
kn-aut-name=三谷政彦
kn-aut-sei=三谷
kn-aut-mei=政彦
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学
en-keyword=MR angiography
kn-keyword=MR angiography
en-keyword=Superior vena cava
kn-keyword=Superior vena cava
en-keyword=Intrathoracic mass
kn-keyword=Intrathoracic mass
END
start-ver=1.4
cd-journal=joma
no-vol=65
cd-vols=
no-issue=5
article-no=
start-page=329
end-page=334
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=201110
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Risk Factors for Infection in Patients with Remitted Rheumatic Diseases Treated with Glucocorticoids
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=It is well known that infection is one of the major causes of morbidity and mortality in rheumatic disease patients treated with high-dose glucocorticoids, especially in the early phase after achievement of disease remission. The aim of this study was to identify the risk factors for infection, with a focus on the dose of glucocorticoids administered, following the achievement of disease remission in rheumatic diseases patients. We retrospectively analyzed the medical records of rheumatic disease patients who had been treated with glucocorticoids. The primary endpoint was the incidence rate of infection during a period from 1 to 2 months after the commencement of treatment. From April 2006 to March 2010, 19 of 92 patients suffered from infection during the observation period. Age≧65 yrs, presence of interstitial pneumonia, diagnosis of systemic vasculitis and serum creatinine level≧2.0mg/dl were found to be univariate predictors for infection. However, only the presence of interstitial pneumonia was an independent risk factor for infection (HR=4.50, 95%CI=1.65 to 14.44) by the Cox proportional hazard model. Even after achievement of clinical remission, careful observation is needed for patients with interstitial pneumonia, more so than for those receiving high-dose glucocorticoids.
en-copyright=
kn-copyright=
en-aut-name=MatsumotoYoshinori
en-aut-sei=Matsumoto
en-aut-mei=Yoshinori
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=1
ORCID=
en-aut-name=SadaKen-ei
en-aut-sei=Sada
en-aut-mei=Ken-ei
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=2
ORCID=
en-aut-name=TakanoMariko
en-aut-sei=Takano
en-aut-mei=Mariko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=3
ORCID=
en-aut-name=ToyotaNoriko
en-aut-sei=Toyota
en-aut-mei=Noriko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=4
ORCID=
en-aut-name=YamanakaRyutaro
en-aut-sei=Yamanaka
en-aut-mei=Ryutaro
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=5
ORCID=
en-aut-name=SugiyamaKoichi
en-aut-sei=Sugiyama
en-aut-mei=Koichi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=6
ORCID=
en-aut-name=WakabayashiHiroshi
en-aut-sei=Wakabayashi
en-aut-mei=Hiroshi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=7
ORCID=
en-aut-name=KawabataTomoko
en-aut-sei=Kawabata
en-aut-mei=Tomoko
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=8
ORCID=
en-aut-name=OtsukaFumio
en-aut-sei=Otsuka
en-aut-mei=Fumio
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=9
ORCID=
en-aut-name=MakinoHirofumi
en-aut-sei=Makino
en-aut-mei=Hirofumi
kn-aut-name=
kn-aut-sei=
kn-aut-mei=
aut-affil-num=10
ORCID=
affil-num=1
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=2
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=3
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=4
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=5
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=6
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=7
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=8
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=9
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
affil-num=10
en-affil=
kn-affil=Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
en-keyword=infection
kn-keyword=infection
en-keyword=rheumatic disease
kn-keyword=rheumatic disease
en-keyword=glucocorticoids
kn-keyword=glucocorticoids
en-keyword=interstitial pneumonia
kn-keyword=interstitial pneumonia
en-keyword=risk factors
kn-keyword=risk factors
END
start-ver=1.4
cd-journal=joma
no-vol=123
cd-vols=
no-issue=2
article-no=
start-page=155
end-page=157
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Becquerel (Bq) and Sievert (Sv)
kn-title=ベクレルとシーベルト
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=KanazawaSusumu
en-aut-sei=Kanazawa
en-aut-mei=Susumu
kn-aut-name=金澤右
kn-aut-sei=金澤
kn-aut-mei=右
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学
END
start-ver=1.4
cd-journal=joma
no-vol=123
cd-vols=
no-issue=2
article-no=
start-page=103
end-page=109
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110801
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Radiosensitization by telomerase-dependent oncolytic adenovirus
kn-title=テロメラーゼ依存的腫瘍融解アデノウイルス製剤による 放射線感受性増強作用
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=DNA修復機能阻害は放射線感受性を増強させるため,DNA修復に関与する因子の阻害剤は放射線増感剤となり得る.我々の開発したテロメラーゼ依存的腫瘍融解アデノウイルス製剤OBP-301(テロメライシン)は,アデノウイルスE1B55kDaタンパクを介して細胞のDNA修復に重要な役割を果たすMRN複合体(Mre11,Rad50,NBS1)を分解する機能を有する.このMRN複合体の分解によりATM(ataxia-telangiectasia mutated)の活性化が抑制され結果的にDNA修復機構が阻害される.我々はOBP-301と放射線との併用が強力な相乗効果を生み出すことをマウスの皮下腫瘍モデルおよび食道癌同所性モデルにおいて証明した.これらの結果はOBP-301が将来有望な放射線増感剤となり得ることだけでなく,E1B55kDaタンパクを産生する腫瘍融解アデノウイルス製剤と放射線との併用が悪性腫瘍に対する有力な治療戦略となり得ることを示す.
en-copyright=
kn-copyright=
en-aut-name=KurodaShinji
en-aut-sei=Kuroda
en-aut-mei=Shinji
kn-aut-name=黒田新士
kn-aut-sei=黒田
kn-aut-mei=新士
aut-affil-num=1
ORCID=
en-aut-name=FujiwaraToshiya
en-aut-sei=Fujiwara
en-aut-mei=Toshiya
kn-aut-name=藤原俊哉
kn-aut-sei=藤原
kn-aut-mei=俊哉
aut-affil-num=2
ORCID=
en-aut-name=ShirakawaYasuhiro
en-aut-sei=Shirakawa
en-aut-mei=Yasuhiro
kn-aut-name=白川靖博
kn-aut-sei=白川
kn-aut-mei=靖博
aut-affil-num=3
ORCID=
en-aut-name=YamasakiYasumoto
en-aut-sei=Yamasaki
en-aut-mei=Yasumoto
kn-aut-name=山崎泰源
kn-aut-sei=山崎
kn-aut-mei=泰源
aut-affil-num=4
ORCID=
en-aut-name=YanoSyuya
en-aut-sei=Yano
en-aut-mei=Syuya
kn-aut-name=矢野修也
kn-aut-sei=矢野
kn-aut-mei=修也
aut-affil-num=5
ORCID=
en-aut-name=UnoFutoshi
en-aut-sei=Uno
en-aut-mei=Futoshi
kn-aut-name=宇野太
kn-aut-sei=宇野
kn-aut-mei=太
aut-affil-num=6
ORCID=
en-aut-name=TazawaHiroshi
en-aut-sei=Tazawa
en-aut-mei=Hiroshi
kn-aut-name=田澤大
kn-aut-sei=田澤
kn-aut-mei=大
aut-affil-num=7
ORCID=
en-aut-name=HashimotoYuuri
en-aut-sei=Hashimoto
en-aut-mei=Yuuri
kn-aut-name=橋本悠里
kn-aut-sei=橋本
kn-aut-mei=悠里
aut-affil-num=8
ORCID=
en-aut-name=WatanabeYuichi
en-aut-sei=Watanabe
en-aut-mei=Yuichi
kn-aut-name=渡辺雄一
kn-aut-sei=渡辺
kn-aut-mei=雄一
aut-affil-num=9
ORCID=
en-aut-name=NomaKazuhiro
en-aut-sei=Noma
en-aut-mei=Kazuhiro
kn-aut-name=野間和広
kn-aut-sei=野間
kn-aut-mei=和広
aut-affil-num=10
ORCID=
en-aut-name=UrataYasuo
en-aut-sei=Urata
en-aut-mei=Yasuo
kn-aut-name=浦田泰生
kn-aut-sei=浦田
kn-aut-mei=泰生
aut-affil-num=11
ORCID=
en-aut-name=KagawaShunsuke
en-aut-sei=Kagawa
en-aut-mei=Shunsuke
kn-aut-name=香川俊輔
kn-aut-sei=香川
kn-aut-mei=俊輔
aut-affil-num=12
ORCID=
en-aut-name=FujiwaraToshiyoshi
en-aut-sei=Fujiwara
en-aut-mei=Toshiyoshi
kn-aut-name=藤原俊義
kn-aut-sei=藤原
kn-aut-mei=俊義
aut-affil-num=13
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=2
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=3
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=4
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=5
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=6
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=7
en-affil=
kn-affil=岡山大学病院 遺伝子・細胞治療センター
affil-num=8
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=9
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=10
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=11
en-affil=
kn-affil=オンコリスバイオファーマ株式会社
affil-num=12
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
affil-num=13
en-affil=
kn-affil=岡山大学大学院医歯薬学総合研究科 消化器外科学
en-keyword=アデノウイルス
kn-keyword=アデノウイルス
en-keyword=E1B55kDa
kn-keyword=E1B55kDa
en-keyword=MRN複合体
kn-keyword=MRN複合体
en-keyword=DNA修復
kn-keyword=DNA修復
en-keyword=放射線感受性
kn-keyword=放射線感受性
END
start-ver=1.4
cd-journal=joma
no-vol=40
cd-vols=
no-issue=7
article-no=
start-page=1283
end-page=1295
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1928
dt-pub=19280731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Ueber Stadien der Strahlenwirkung auf dem Uteruskrebs in obduzierten F?llen I. Ueber das Plattenepithelkarzinom
kn-title=剖檢例ニ就テ爲セル子宮癌ニ對スル放射線作用ノ檢索 其ノ1 扁平上皮癌ニ就テ
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Die durch zwei Serien von R?ntgen-Radium-bestrahlung (R?ntgenbestrahlung nach Seitz und Winz, 30-31 mgr. von RaBr im Kraterf?rmigen Uterushals) bedingten Ver?nderungen der Krebszellen sind verschieden je nach der Portio vaginalis und Collum uteri, Uterusschleimhaut und Muskelschicht, Rectalseite und Blasenseite, und einzellnen in demselben Krebsnester. 1) Die Krebszellen der Halsgegend sind hochgradiger ver?ndert als diejenigen der Portio vaginalis. 2) In der Muskelschicht verh?lt sich die Ver?nderung verschieden nach den Zust?nden des umgebenden Gewebs. Die Krebszellen, welche im durch Radiumbestrahlung zur Nekrose anheimfallenden umgebenden Gewebe sich befinden, sind st?rker ver?ndert als diejenigen, welche im nicht nekrotisierenden gesunden Bindegewebe sich vorfinden. 3) Die Krebszellen, welche in Muskelschicht sich befinden, sind st?rker beeinflusst als die in Uterusschleimhaut sich vorfindenden. 4) In demselben Nester zeigen die Krebsschichten die verschiedenartigen ver?nderungen u. z. das gemischte Gebilde von Haendly. 5) Ich bin nicht im stande, nirgends die unver?nderten Krebszellen zu konstazieren, wie Bumm, Robert-Myer, Stern, Bott angegeben haben. 6) Nirgends sind Kernteilungsfiguren der Krebszellen nachweisbar.
en-copyright=
kn-copyright=
en-aut-name=MaruyamaIchiro
en-aut-sei=Maruyama
en-aut-mei=Ichiro
kn-aut-name=丸山一郎
kn-aut-sei=丸山
kn-aut-mei=一郎
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山醫科大學附屬醫院産科婦人科教室
END
start-ver=1.4
cd-journal=joma
no-vol=40
cd-vols=
no-issue=6
article-no=
start-page=1087
end-page=1102
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1928
dt-pub=19280630
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Ueber das Verhalten der Krebsinfiltration im Beckenbindegewebe gegenueber den Uretheren, und zugleich, Ueber Strahleneinfluss der secund?ren Krebsigen Infiltration der Uretheren
kn-title=骨盤結締織ニ於ケル癌腫浸潤ノ輸尿管ニ對スル態度 附 輸尿管ニ於ケル續發性癌性浸潤ニ對スル放射線ノ影響
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Seit dem 13 ten Yahre Taisho habe ich an hiesiger gyn?kologischer Klinik die gesammten Urogenitalorgane von den an fortgeschrittenem Uterushalskrebs Abgestor-benen herausgenommen und von den im hartinfiltrierten Beckenbindegewebe einge-bettenen Uretheren zwei Punkte besonders in Betracht bezogen: A. Verhalten der Krebsinfiltration gegenueber den Uretheren. B. Strahleneinfluss der secund?ren krebsigen Infiltration der Uretheren. Und durch microchemische Untersuchungen habe ich folgende Resultate: I. Obgleich im Allgemeinen die Urethren gegen krebsiger Infiltration grossen Widerstand leistet, k?nnen alle Uretherschichten Kreibsige Eingriffe nicht vermeiden, wenn das Beckenbindegewebesinfiltration sehr hochgradig ist. II. Betreffs der Krebsinfiltration der Uretheren sind die Krebsnester und Stroma durch zwei Serien von R?ntgen-Radium-bestrahlung (R?ntgenbestrahlung nach Seitz und Winz, 30-31 mgr. von RaBr im Kraterf?rmigen Uterushals) bedeutend beeinfiusst u. z. a) Die Zellen sind bedeutend vergr?ssert und deren Grenze ist sehr deutlich. Die betreffenden Zellenvergr?sserungen sind durch Volumenzunahme von Protoplasma und Kern bedingt. Die Kerns sind blasig und unregelm?ssig tingiert, sodass feiner Bau derselben schwer zu konstatieren ist. Das Protoplasma ist deutlich vermehrt, unregel-m?ssig verf?rbt und mit grossen und kleinen Vacuolen durchsetzt. Hier und da bemerkt man die Riesenzellen, welche durch Einschmelzen entstehen. Die Kerne sind staubartig zerst?rt und dadurch verschwunden, so dass bald resorbierbare kernlose Zellk?rper entstehen. In anderen F?llen sind zuerst die Protoplasmen verschwunden gegangen und die Kerne sind allein ?brig geblieben. Die Kernteilungsfiguren sind nirgends zu sehen. b) Im Stroma sieht man stellenweise die kleinrundzelleninfiltration und Hyper?mie. c) In einzelnen Krebsnestern kann man Eindringen von Bindegewebe konstatieren. d) Die Ver?nderungen, welche in der secund?rer Krebsinfiltration durch Bestrahlung auftreten, sind sehr ?hnlich mit denen von Uteruskrebs.
en-copyright=
kn-copyright=
en-aut-name=MaruyamaIchiro
en-aut-sei=Maruyama
en-aut-mei=Ichiro
kn-aut-name=丸山一郎
kn-aut-sei=丸山
kn-aut-mei=一郎
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山醫科大學附属醫院産科婦人科教室
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=テロメラーゼ依存的腫瘍融解アデノウイルス製剤によるDNA修復阻害を介したヒト癌細胞の放射線感受性増強作用
kn-title=Telomerase-Dependent Oncolytic Adenovirus Sensitizes Human Cancer Cells to Ionizing Radiation via Inhibition of DNA Repair Machinery
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=KurodaShinji
en-aut-sei=Kuroda
en-aut-mei=Shinji
kn-aut-name=黒田新士
kn-aut-sei=黒田
kn-aut-mei=新士
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=CT-直線加速器システムを用いた前立腺癌外部放射線治療に対する日々の前立腺位置の比較: 同室設置CT画像対デジタル再構成画像
kn-title=Comparison of daily prostate positions during conformal radiation therapy of prostate cancer using an integrated CT-linear accelerator system: in-room CT image versus digitally reconstructed radiograph
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=AoyamaHideki
en-aut-sei=Aoyama
en-aut-mei=Hideki
kn-aut-name=青山英樹
kn-aut-sei=青山
kn-aut-mei=英樹
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学
END
start-ver=1.4
cd-journal=joma
no-vol=
cd-vols=
no-issue=
article-no=
start-page=
end-page=
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=20110325
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=煙草中の(210)Pbと(40)Kの放射能レベルと喫煙による放射線被曝の評価
kn-title=An assessment of radioactivity levels of (210)Pb and (40)K in tobacco and radiation exposure from smoking
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
en-copyright=
kn-copyright=
en-aut-name=NagamatsuTomohiro
en-aut-sei=Nagamatsu
en-aut-mei=Tomohiro
kn-aut-name=永松知洋
kn-aut-sei=永松
kn-aut-mei=知洋
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学
END
start-ver=1.4
cd-journal=joma
no-vol=27
cd-vols=
no-issue=
article-no=
start-page=46
end-page=51
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2011
dt-pub=201105
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Introduction of the facility for laboratory animals at National Institute of Radiological Sciences
kn-title=(独)放射線医学総合研究所実験動物開発・管理課の紹介
en-subtitle=
kn-subtitle=
en-abstract=放射線医学総合研究所(放医研)は1957年の創立以来、放射線と人々の健康に関わる研究開発に多数分野の学問を糾合して総合的に取り組む国内で唯一の研究開発機関である。放医研の動物実験の特徴は@多種の線種・核種の放射性物質を実験動物に照射後、長期に渡って飼育することによる生物学的影響を検索すること。A そのため、微生物学的に厳密に統御された動物を用いる必要があること、B放射性物質を用いた多種のイメージング装置による撮像の2点である。用いられる動物種は魚類から霊長類まで幅広く、飼育期間も数日で終了するものもあれば、約2年間に渡って飼育する場合もある。更に、実験終了後の動物死体、臓器はRI廃棄物、核燃料廃棄物として扱
わねばならないと云う制約がある等通常の動物実験では必要とされない特殊な対応が求められている。放医研構内にこれらの動物実験施設は11ヶ所設置されており、放射線管理区域と動物管理区域がこれらの施設内で混在していることから実験者の立ち入りについても厳重な管理とそれに先立つ教育訓練を実施している。このように国内はもとより、国外でも稀な施設管理が求められているが2009年に国公私動協による外部検証で施設管理および動物倫理・福祉に配慮した適正な動物実験の遂行について高い評価を得た。
kn-abstract=Since its founding in 1957, the National Institute of Radiological Sciences (NIRS) has been the only research and development institution in Japan dedicated to comprehensive research and development of radiation and health with various scientific disciplines. The main characteristics of laboratory animal experiments at NIRS are as follows: (1) the study of long-term biological effects on labol'8tory animals after exposure of various line types to nuclides of radioactive substances, (2) the use of animals maintained under strict quality control from a microbiological viewpoint, and (3) the use of wide range of imaging devices to capture images when
radioactive substances are used. We deal with various types of animals, from fish to primates, and the breeding and feeding periods of
these animals range from few days to approximately 2 years. Furthermore, special attention is given to carcasses and organs of laboratory animals that are treated as RI as well as nuclear fuel wastes, whereas such a restriction does not apply in regular experiments. There are 11 animal experimentation facilities at NIRS. The radiation control and animal management areas are located next to each other on the same site, and radiation workers at these areas are under supervision, strict management, and control. Safety education and training program are also provided to workers as a prerequisite. Not only from a Japanese but also from a global standard viewpoint, a high level of safety management is required for these facilities. During an external assessment in 2009, we received high evaluation marks from the Japanese Association of Laboratory Animal Facilities of National University Corporations and the Japanese Association of Laboratory Animal Facilities of Public and Private Universities for performing animal experiments with consideration of the ethical aspects and well-being of laboratory animals, as well as for the management of facilities.
en-copyright=
kn-copyright=
en-aut-name=NishikawaTetsu
en-aut-sei=Nishikawa
en-aut-mei=Tetsu
kn-aut-name=西川哲
kn-aut-sei=西川
kn-aut-mei=哲
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=独立行政法人放射線医学総合研究所基盤技術センター研究基盤技術部実験動物開発・管理課
END
start-ver=1.4
cd-journal=joma
no-vol=49
cd-vols=
no-issue=11
article-no=
start-page=2189
end-page=2196
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1937
dt-pub=19371130
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Nachtr?ge zu den St?dien ?ber den Einfluss der Kathodenstrahlen auf den Eierstock, die Leber, die Schilddruse und die Milz beim Kaninchen. Physikalische Untersuchungen der von der Kathodeustrahlenr?hre ausgesandten Strahlen.
kn-title=陰極線ノ家兎卵巣,肝臟,甲状腺,脾臟ニ及ボス影響ニ關スル研究補遺 陰極線管ヨリ發スル放射線ノ理學的檢査
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Die Verfasserin stellte physikalische Untersuchungen ?ber die von der Kathodenstrahlenr?hre ausgesandte Strahlen an, um eine sichere Best?tigung daf?r zu finden, dass die Kathodenstrahlen aus der Kathodenstrahlenrohre durch deren Wand hindurch auch wirklich nach aussen dringen, n?mlich der Kathodenstrahlenr?hre, welche die Verfasserin ehemals bei ihren Tierversuchen zur Erforschung der biologischen Wirkung der Kathodenstrahlen benutzte. Die Ergebnisse sind folgende: 1) Die aus der Kathodeustrahlenrohre herkommenden Strahlen biegen sich in einem magnetischen Felde bezw. elektrischem Kraftfelde; sie konnnen auch das Bromnatrium verf?rben, welches auf die ?ussere Flache der Antikathodenglasswand geschmiert wurde. Diese Ph?nomena finden sich keinwegs bei den X-Strahlen; daraus ergibt sich ohne weiteres dass die Kathodenstrahlen durch die dunne Antikathodenglasswand der Kathodenstrahlenrohre von innen heraus ausstrahlen. 2) Es ist m?glich, dass die X-Strahlen an der Stelle der Antikathdenglasswaud, wo die Kathodenstrahlen anstossen, eutstehen; doch betr?gt ihre Menge, mit dem K?stner'schen Eichstandger?t gemessen, im Antikathodenrohrenwand-Blendeabstand von 2cm nur 0,011 HED pro Minute. 50% der totaleu Dose der X-Strahlen, die von der Kathodenstrahleur?hre herkommen, werdeu durch eine 0,1mm dicke Alminiumplatte resorbiert. Das bedeutet, dass die von der Kathodeustrahlenr?hre ausstrahlendeu X-Strahlen sehr weich und schwach penetrieren sind, und dass ihre gesamte Dose nur geringf?gig ist. Aus der erwahuten Tatsache geht hervor, dass es sich bei den schou berichteten hystologischen Ver?nderungen, die durch die Bestrahlung mit der Kathodeustrahlenrohre hervorgerufen werden, um die Wirkungen der Kathodenstrahlen handelt, die aus der betreffenden Kathodenstrahlenr?hre durch ihre Wand hindurch herausstr?men.
en-copyright=
kn-copyright=
en-aut-name=MoriyaChiyono
en-aut-sei=Moriya
en-aut-mei=Chiyono
kn-aut-name=守屋千代野
kn-aut-sei=守屋
kn-aut-mei=千代野
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山醫科大學解剖學教室
END
start-ver=1.4
cd-journal=joma
no-vol=50
cd-vols=
no-issue=9
article-no=
start-page=1845
end-page=1866
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1938
dt-pub=19380930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Experimentelle Studien uber den Einfluss der Radiumbestrahlung anf den Geh?rorgan
kn-title=ラヂウム放射線」ノ聽器ニ及ボス影響ニ就テノ實驗的研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Experimentelle Untersuchungen ?ber den Einfluss der Radiumbestrahlung auf die Nervenendigungen des Gehororgans, besonders des Labyrinths, wurden bisher nur von wenigen Autoren angestellt und als Resultat zeigt sich fast immer an jeder Partie der Endigungen des N. Acusticus ein Degenerationsprozess. Aber uber die Frage, wie und in welcher Weise dieser Degenerationsprozess auftritt, d.h. uber die Frage der Resistenzkraft der Nenvenendigungen gegenuber der Radiumbestrahlung gehen die Meinugen der Autoren so sehr auseinauder, dass man dauber keine bestimmte Angaben machen kann. Um dieses Problem n?her zu verfolgen hat Verfasser Experimente mit Meerschweinchen ausgefuhrt. Nach Anwendung von 1. od. 2 Radiumnadeln mit 5,5mg Bromradiumkontinuierlich 24 Stunden bis 25 Tage lang, von innen oder aussen in die Seite der eigentlichen Mittelohrblase des Versuchtieres, wurde die Vitalfixation in verschiedenen Zeitr?umen ausgefuhrt, sodass der Zustand aller Partien der Endigung der N. Acusticus nach der entsprechenden Bestrahlungsdauer genau untersucht werden konnte. Bei der Untersuchung von Ganglienzellen wurden die Pr?parate in 2,5mm dicke Serienschnitte zerlegt und ausschliesslich Tanaka'sche Methode angewandt.Die Resultate sind folgende: 1) Durch kontinuierliche Bestrahlung des Gehororgans des Meerschweinchens mit einer geringen Dosis Radium wurde primare Degeneration an allen Endigungen des Labyrinths hervorgerufen. 2) Auftreten des Degenerationsprozesses am Cochlearapparat ist dem Grade und der Zeit nach je nach der Affinitat der Lokalit?t verschieden, n?mlich am fr?hesten und deutlicheten am Corti'schen Organ, dann an den Ganglienzellen, und am sp?testen und leichtesten an den Nervenfasern; es herrscht aber dabei niemals ein Abh?ngigkeitsverhaltniss. 3) Storungsgrade am Vestibularapparat viel weniger als an der Cochlea, aber finden sich der Auftretensmodus des Degenerationsprozesses ist an beiden Apparaten ganz gleich. 4) Die durch die Radiumbestrahlung hervorgerufene Degeneration des Labyrinths wird trotz gleicher Gesamtdosis um so deutlicher herbeigefuhrt, je grosser die l-malige verbrauchte Radiumdosis ist. 5) Diese Degeneration hat ein bestimmtes latentes Stadium. 6) Sie ist je nach Bestrahlungsdosis, Anwendungsweise, Lebensbauer nach der Bestrahlung, und Alter des Versuchstieres verschieden. In diesem Experiment erweisen sich nirgends Ver?nderungen auf der nicht bestrahlten Seite des Geh?rorgans.
en-copyright=
kn-copyright=
en-aut-name=DoiShin'ichi
en-aut-sei=Doi
en-aut-mei=Shin'ichi
kn-aut-name=土井眞一
kn-aut-sei=土井
kn-aut-mei=眞一
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山醫科大學耳鼻咽喉科教室
END
start-ver=1.4
cd-journal=joma
no-vol=55
cd-vols=
no-issue=7
article-no=
start-page=1040
end-page=1041
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1943
dt-pub=19430731
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Radiare streifige Narben um den Mund
kn-title=口圍非黴毒性放射線状瘢痕
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Ein 28 j?hriger junger Bauer hatte radi?re streifige Narben an beiden Mundwinkeln: Rechts 5, links 3 Streifen. Jede Narbe war 2-3cm lang, 1-2mm breit, regelm?ssig und geradlinig. Die Unterlippe st?lpte nicht aus. Der Kranke war ganz frei von syphilitischen Symptomen.
en-copyright=
kn-copyright=
en-aut-name=NarukawaTosimitu
en-aut-sei=Narukawa
en-aut-mei=Tosimitu
kn-aut-name=成川俊光
kn-aut-sei=成川
kn-aut-mei=俊光
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山醫科大學皮膚科泌尿器科教室
END
start-ver=1.4
cd-journal=joma
no-vol=67
cd-vols=
no-issue=3-4
article-no=
start-page=883
end-page=888
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1955
dt-pub=19550430
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=On the Effect of X-irradiation upon the Urease Activity
kn-title=レ線照射の酵素作用に及ぼす影響Ureaseの尿素分解作用に及ぼす影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In order to investigate the influence of X-irradiation upon the urease, the authors performed several experiments and obtained the following conclusion: 1) The urease action are influenced by X-irradiation. 2) The activity of urease is strengthened in the case of irradiation with from 40r to 120r, and inhibited in the case of irradiation ranging from 140r to 200r or 400r. 3) The effect of X-irradiation upon urease action is caused by the irradiation of urease itself, and not of the substrate (urea). 4) When KCN is added to the urease urea mixture, the urease activity is activated in proportion to the concentration of KCN. In the case of an addition of KCN to the urease urea mixture, the effect of X-irradiation upon the urease activity is slight in case of strong concentration of KCN, but appears distinctly in case of weak concentration of KCN. 5) When CuSO(4) is added to the urease urea mixture, the urease activity is inhibited in proportion to the concentration of CuSO(4). In the case of addition of CuSO(4) to the urease urea mixture, the effect of X-irradiation upon the urease activity is seen slightly in case of strong concentration of CuSO(4), but distinctly in case of weak concentration of CuSO(4). 6) In the case of solar radiation, the urease activity is inhibited in proportion to the time of solar radiation, and the urease activity which is inhibited by solar radiation for 30 minutes, is reactivated by X-irradiation with 80r.
en-copyright=
kn-copyright=
en-aut-name=NakanishiY.
en-aut-sei=Nakanishi
en-aut-mei=Y.
kn-aut-name=中西喜雄
kn-aut-sei=中西
kn-aut-mei=喜雄
aut-affil-num=1
ORCID=
en-aut-name=KandaM.
en-aut-sei=Kanda
en-aut-mei=M.
kn-aut-name=神田瑞穗
kn-aut-sei=神田
kn-aut-mei=瑞穗
aut-affil-num=2
ORCID=
en-aut-name=MimuraK.
en-aut-sei=Mimura
en-aut-mei=K.
kn-aut-name=三村公正
kn-aut-sei=三村
kn-aut-mei=公正
aut-affil-num=3
ORCID=
en-aut-name=YamamotoM.
en-aut-sei=Yamamoto
en-aut-mei=M.
kn-aut-name=山本道夫
kn-aut-sei=山本
kn-aut-mei=道夫
aut-affil-num=4
ORCID=
en-aut-name=MurakamiT.
en-aut-sei=Murakami
en-aut-mei=T.
kn-aut-name=村上達郎
kn-aut-sei=村上
kn-aut-mei=達郎
aut-affil-num=5
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線科教室
affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線科教室
END
start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=11
article-no=
start-page=2789
end-page=2806
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19571130
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Electron Microscopy of the Human Cervical Cancer, with Especial Reference to the Change of Radiation and its Radiosensitivity
kn-title=子宮頸癌の電子顕微鏡的研究(特に放射線変化と感受性に就いて)
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=I have examined 57 cases of the uterine cervical cancer and 2 cases of the normal uterine cervix (non-pregnant and pregnant) with electron microscope. 1) Normal uterine cervix. The nucleocytoplasmic ratio becomes lower, and mitochondria a fewer from the profundal layer to the superficial one. The intercellular bridge develops in superficial spinal layer highly, and the cytoplasmic communication may be seen at one part of bridge. The tonofibrils of neighbouring cells don't connect with each other, and they make themselves into a bundle in the intercellular bridge and build the Bizozzero's node described by Porter and Takaki. But the situation and relationship of the Biyozzero's node in the bridge don't quite accord with their opinions. During pregnancy the cytoplasm of superficial layer is rather granular than fibrous, and characteristic intercellular sinus may also be recognized. 2) Carcinoma of the cervix. The structure of cellular border is simple in the epidermoid carcinoma. The mitochondia, endoplasmic reticulnm and Golgi body are observed in the cytoplasm. Although there is no statistical significancy, inclusion bodies have tendency to increase by radiation. The nuclear membrane is double layered, but doesn't look such thickening as observed with optical microscope. The onucleoplasm is composed of fine granules which become coarse or nodular by degeneration. The nucleoli have no definite form.
They consist of highly electron dense particles and possess no limiting membranes. There are many mitotic figures in cancer cells. The cell, on the whole, revealed 3 stratified structure in the prophase, and 2 stratified one in the metaphase. In the adenocarcinoma, I notice the characteristic findings that have many vacuoles and lipid or secretory granules in its cytoplasm. 3) Autolytic changes of cervical cancer.
The extirpated cancer tissue shows remarkable changes within 40 minutes in 20°C normal saline solution. 4) Changes of cancer cells incident to radiation. The radiative change differs from the autolytic one in quantity and duration. The fatty and vacuolar degeneration, giant cell and inclusion body appear in the radiation newly, but not in the autolysis. There is no essential difference between x-ray and radium about the effect. The mitochondrias are the first to suffer from radiation, but the nuclear and the cell membrane are the last to change. As the radiative changes, the thickening of nuclear membrane, vacuolar degeneration and congregated picture of nucleoplasm are hardly seen in the electron microscopy, but not rarely in the optical one. 5) Relationship of radiosensitivity of uterine cervical carcinoma to histopathological picture and clinical findings. The spindle type is more radiosensitive than the transitional and spinal one. Especially the significant difference was recognized between the spindle and the transitional. The high density of cancer cells is more sensitive than the low significantly. But the radiosensitivity has no significant relation with Imai's C. P. L. classification and the other clinical findings. About the radiosensitivity, the electron microscopical findings accord with the optical one relatively.
en-copyright=
kn-copyright=
en-aut-name=OuYun Yen
en-aut-sei=Ou
en-aut-mei=Yun Yen
kn-aut-name=欧雲炎
kn-aut-sei=欧
kn-aut-mei=雲炎
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部産婦人科学教室
END
start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=8
article-no=
start-page=2105
end-page=2110
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=On the Virus Pneumonia Discovered in the Northern Mountain Regions of Okayama Prefecture
kn-title=岡山県北部山間地方に続発した「ビールス」肺炎に就いて
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Ever since June 1956 mainly centering around Hayashino, Mimasakacho, the mountain regions in the northern part of Okayama Prefecture we have frequently encountered virus pneumonia which by their roentgenographs were misdiagnosed for pulmonary tuberculosis. By November of the same year there appeared the patients indicative of virus pneumonia from their roentgenographs of chest, among pupils of such grade schools as Hayashino, Toyokuni, Toyoda, Narahara, and Kumon Grade Schools, all around Hayashino. Therefore, indirect x-ray photographs had been taken of 2, 019 pupils and found 381 cases whose shadow indicated what might be thought to be of virus pneumonia. We present herewith a report on x-ray findings of thes cases, percentage of the position of shadow appearance, clinical symptoms as well as on x-ray differentiation.
en-copyright=
kn-copyright=
en-aut-name=YamamotoMichio
en-aut-sei=Yamamoto
en-aut-mei=Michio
kn-aut-name=山本道夫
kn-aut-sei=山本
kn-aut-mei=道夫
aut-affil-num=1
ORCID=
en-aut-name=TaziriTamotsu
en-aut-sei=Taziri
en-aut-mei=Tamotsu
kn-aut-name=田尻保
kn-aut-sei=田尻
kn-aut-mei=保
aut-affil-num=2
ORCID=
en-aut-name=KawaharaHiroshi
en-aut-sei=Kawahara
en-aut-mei=Hiroshi
kn-aut-name=河原宏
kn-aut-sei=河原
kn-aut-mei=宏
aut-affil-num=3
ORCID=
en-aut-name=FunabikiSadao
en-aut-sei=Funabiki
en-aut-mei=Sadao
kn-aut-name=船曳定雄
kn-aut-sei=船曳
kn-aut-mei=定雄
aut-affil-num=4
ORCID=
en-aut-name=EgawaMasao
en-aut-sei=Egawa
en-aut-mei=Masao
kn-aut-name=江川昌男
kn-aut-sei=江川
kn-aut-mei=昌男
aut-affil-num=5
ORCID=
en-aut-name=NishishitaSoichi
en-aut-sei=Nishishita
en-aut-mei=Soichi
kn-aut-name=西下創一
kn-aut-sei=西下
kn-aut-mei=創一
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=2
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=6
en-affil=
kn-affil=岡山大学医学部放射線科
END
start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=8
article-no=
start-page=2097
end-page=2104
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570830
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=On the Two Cases of What are Thought to be "Porzellangallenblase"
kn-title=Porzellangallenblaseと考えられる二例に就いて
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The application of x-rays in the diagnosis of gall-bladder diseases is an old, well-known method, but since this is used mainly in taking a simple photograph, it is difficult to obtain a good roentgenological picture. Recently with the successive advent of excellent opaque substances such as Biligrafin, Telepaque and Priodax the diagnosis of gall bladder diseases has become quite easy, but two cases on which we report here are, on the contrary, the cases whose diagnosis has been made more difficult on account of the appearance of these excellent contrast media. This "Porzellangallenblase" is an extremely rare disease and it was first reported by H. D. Fl?rchen (1929) in the "Zentralblatt d. Chirurgie". It presents a piture identical with the one taken at the time when opaque substance is administered. As for the symptoms, the patient mainly complains of something similar to gall-stone; and in our cases, one was suspected of kidney stone and the other was of gall-bladder disease. Both of these were discovered at the x-ray examinations of the stomach, and each in their roentgenograph presented the stone in their bile duct. In addition their roentgenograph of the gall-bladder gave the picture identical with the one taken when opaque substance had been given. We present this case report as these are very rare cases among Japanese people in the light of available literatures.
en-copyright=
kn-copyright=
en-aut-name=YamamotoMichio
en-aut-sei=Yamamoto
en-aut-mei=Michio
kn-aut-name=山本道夫
kn-aut-sei=山本
kn-aut-mei=道夫
aut-affil-num=1
ORCID=
en-aut-name=NishishitaSoichi
en-aut-sei=Nishishita
en-aut-mei=Soichi
kn-aut-name=西下創一
kn-aut-sei=西下
kn-aut-mei=創一
aut-affil-num=2
ORCID=
en-aut-name=AndoRyo
en-aut-sei=Ando
en-aut-mei=Ryo
kn-aut-name=安東龍
kn-aut-sei=安東
kn-aut-mei=龍
aut-affil-num=3
ORCID=
en-aut-name=MorimotoYoshiki
en-aut-sei=Morimoto
en-aut-mei=Yoshiki
kn-aut-name=森本義樹
kn-aut-sei=森本
kn-aut-mei=義樹
aut-affil-num=4
ORCID=
en-aut-name=WakimotoMasahiro
en-aut-sei=Wakimoto
en-aut-mei=Masahiro
kn-aut-name=脇本正寛
kn-aut-sei=脇本
kn-aut-mei=正寛
aut-affil-num=5
ORCID=
en-aut-name=HashigamiTadashi
en-aut-sei=Hashigami
en-aut-mei=Tadashi
kn-aut-name=橋上正
kn-aut-sei=橋上
kn-aut-mei=正
aut-affil-num=6
ORCID=
en-aut-name=YasudaMinoru
en-aut-sei=Yasuda
en-aut-mei=Minoru
kn-aut-name=安田稔
kn-aut-sei=安田
kn-aut-mei=稔
aut-affil-num=7
ORCID=
en-aut-name=TaziriTamotsu
en-aut-sei=Taziri
en-aut-mei=Tamotsu
kn-aut-name=田尻保
kn-aut-sei=田尻
kn-aut-mei=保
aut-affil-num=8
ORCID=
en-aut-name=FunabikiSadao
en-aut-sei=Funabiki
en-aut-mei=Sadao
kn-aut-name=船曳定雄
kn-aut-sei=船曳
kn-aut-mei=定雄
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部放射線教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線教室
affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線教室
affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線教室
affil-num=6
en-affil=
kn-affil=
affil-num=7
en-affil=
kn-affil=岡山大学医学部放射線教室
affil-num=8
en-affil=
kn-affil=岡山大学医学部放射線教室
affil-num=9
en-affil=
kn-affil=岡山大学医学部放射線教室
END
start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=5
article-no=
start-page=1335
end-page=1340
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570531
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Influence of X-Ray on the Enzymic Action of Organ
kn-title=臟器酵素におよぼすレ線の影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The paper is the report on the results obtained from the experimental studies to find out what extent does the influence of X-Ray affect the enzymic action of organ, the basic metabolic process of living organism. Summary of the results: 1. In healthy mature rabbits, with three organs, namely, the brain, liver and kidney, the amount found of Kateptase, Amylase and Urease were highest in the kidneys and the livers came the next, while the brains contained the least. With Arginase, it was found to be highest in the livers, and kidneys were the next, but the brains had the least. 2. Healthy mature rabbits were submitted with daily X Ray radiaton of 300 r for a period of 10 days and the animals were killled when the total dosage had reached 3000 r, and respective action of Kateptase, Amylase, Arginase and Urease in brain, liver and kidney were compared with the nonirradiated rabbits. It was found that the action of Kateptase, Arginase and Urease of these three organs have been markedly increased by the X Ray radiation and degree of influence was the highest in the brains: with Amylase action in respective organ, it was decreased and its effect was most noticeable in the brain.
en-copyright=
kn-copyright=
en-aut-name=KandaMizuho
en-aut-sei=Kanda
en-aut-mei=Mizuho
kn-aut-name=神田瑞穗
kn-aut-sei=神田
kn-aut-mei=瑞穗
aut-affil-num=1
ORCID=
en-aut-name=NakanishiYoshio
en-aut-sei=Nakanishi
en-aut-mei=Yoshio
kn-aut-name=中西喜雄
kn-aut-sei=中西
kn-aut-mei=喜雄
aut-affil-num=2
ORCID=
en-aut-name=MimuraKimimasa
en-aut-sei=Mimura
en-aut-mei=Kimimasa
kn-aut-name=三村公正
kn-aut-sei=三村
kn-aut-mei=公正
aut-affil-num=3
ORCID=
en-aut-name=IshikawaMasaji
en-aut-sei=Ishikawa
en-aut-mei=Masaji
kn-aut-name=石川正次
kn-aut-sei=石川
kn-aut-mei=正次
aut-affil-num=4
ORCID=
en-aut-name=KogataSeiichi
en-aut-sei=Kogata
en-aut-mei=Seiichi
kn-aut-name=古形誠一
kn-aut-sei=古形
kn-aut-mei=誠一
aut-affil-num=5
ORCID=
en-aut-name=MiyoshiYoshinori
en-aut-sei=Miyoshi
en-aut-mei=Yoshinori
kn-aut-name=三好義則
kn-aut-sei=三好
kn-aut-mei=義則
aut-affil-num=6
ORCID=
en-aut-name=YoshiiShimizu
en-aut-sei=Yoshii
en-aut-mei=Shimizu
kn-aut-name=吉井清水
kn-aut-sei=吉井
kn-aut-mei=清水
aut-affil-num=7
ORCID=
en-aut-name=YamamotoMichio
en-aut-sei=Yamamoto
en-aut-mei=Michio
kn-aut-name=山本道夫
kn-aut-sei=山本
kn-aut-mei=道夫
aut-affil-num=8
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=4
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=5
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=6
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=7
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=8
en-affil=
kn-affil=岡山大学医学部放射線医学教室
END
start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=3
article-no=
start-page=915
end-page=924
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570331
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=About the Effect of Ethanol (Ethylalcohol) on the Restoration of X-rays Injury
kn-title=エタノールの放射線障碍の恢復に及ぼす影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The result of the experiment which ethylalcohol affect on the X-rays injury advantageously reported by M. Yamamoto who is our co-worker at the same time ago, and we attempted to this experiment that whether ethylalcohol affect on the restoration of X-rays injury usefully or not, and this experiment carried out on 3 groups as following: 1) A group of mice in wich ethylalcohol was not used, 2) B group of mice in which ethylalcohol was used only for irradiated period with 100r×10, 3) C group of mice in which ethylalcohol was used not only for irradiated period with 100r×10, but for 15 days, 30 days after the irradiated with 100r×10, and we found out following results in this experiment. In this case there were more histological restorating figures of spleen, liver injuries than in the case of mice in which ethylalcohol was not used.
en-copyright=
kn-copyright=
en-aut-name=YamamotoM.
en-aut-sei=Yamamoto
en-aut-mei=M.
kn-aut-name=山本道夫
kn-aut-sei=山本
kn-aut-mei=道夫
aut-affil-num=1
ORCID=
en-aut-name=MorimotoY.
en-aut-sei=Morimoto
en-aut-mei=Y.
kn-aut-name=森本義樹
kn-aut-sei=森本
kn-aut-mei=義樹
aut-affil-num=2
ORCID=
en-aut-name=NishishitaS.
en-aut-sei=Nishishita
en-aut-mei=S.
kn-aut-name=西下創一
kn-aut-sei=西下
kn-aut-mei=創一
aut-affil-num=3
ORCID=
en-aut-name=SadatoshiK.
en-aut-sei=Sadatoshi
en-aut-mei=K.
kn-aut-name=貞利庫司
kn-aut-sei=貞利
kn-aut-mei=庫司
aut-affil-num=4
ORCID=
en-aut-name=AndoR.
en-aut-sei=Ando
en-aut-mei=R.
kn-aut-name=安東龍
kn-aut-sei=安東
kn-aut-mei=龍
aut-affil-num=5
ORCID=
en-aut-name=YamamotoK.
en-aut-sei=Yamamoto
en-aut-mei=K.
kn-aut-name=山本弘毅
kn-aut-sei=山本
kn-aut-mei=弘毅
aut-affil-num=6
ORCID=
en-aut-name=WakimotoM.
en-aut-sei=Wakimoto
en-aut-mei=M.
kn-aut-name=脇本正寛
kn-aut-sei=脇本
kn-aut-mei=正寛
aut-affil-num=7
ORCID=
en-aut-name=YasudaM.
en-aut-sei=Yasuda
en-aut-mei=M.
kn-aut-name=安田稔
kn-aut-sei=安田
kn-aut-mei=稔
aut-affil-num=8
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=2
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=6
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=7
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=8
en-affil=
kn-affil=岡山大学医学部放射線科
END
start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=1
article-no=
start-page=129
end-page=136
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=On the Urinary and Fecal Fistulae Complicated with Radiological Treatment in Cancer of the Uterine Cervix (Data of 21 years from 1934 to 1954 at the Dept. of Obstc. & Gynec., Okayama University)
kn-title=子宮頸癌放射線治療に合併せる尿・糞瘻に就いて(岡大婦人科に於ける昭和9年より昭和29年迄の観察)
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=During twenty one years from 1934 to 1954 inclusive, 1,974 cases of cancer of the uterine cervix were treated by radiation therapy in the gynecological department of Okayama University. The urinary and fecal fistulae were found in 13 cases (0.7%) during the I. series and in 30 cases (1.5%) after leaving the hospital. There were; urinary fistulae 1.2% (22 cases of vesico-vaginal, 1 case of urethro-vaginal), fecal fistulae 0.9% (18 cases of rectovaginal), and urino-fecal fistulae 0.1% (2 cases of recto-vesico-vaginal). Thirteen cases of them showed evidently signs of fistulae during admission, and their subjective symptoms were as follows: in the urinary fistula, 7 cases out of 11 complained of vesico-urethral irritation symptoms; in the fecal fistula, one case out of 2 complained of mucous stool and of discomfort in the anal region. There were observed no relations to their age groups (less than 49 and over 50), the deliveries (less than 4 times including none, and over 5 times), and the state of presence of the cancerous infiltration in the vaginal wall on observation in the first examination. There was a tendency to produce urinary and fecal fistulae more frequently in the ulcerative or crateriform cancers than in the cauli flower-like or erosive, and in the progressed cancer patients. The curability was very low in these fistulae occurred during the radiological treatment. Most of them died of cancer; about 1/2 of them were within one year, about 1/4 within 2 to 5 years and the rest 1/4 belonged to the cases of 5-year survivals.
en-copyright=
kn-copyright=
en-aut-name=MasaokaYoshinori
en-aut-sei=Masaoka
en-aut-mei=Yoshinori
kn-aut-name=正岡吉則
kn-aut-sei=正岡
kn-aut-mei=吉則
aut-affil-num=1
ORCID=
en-aut-name=NagaseIsamu
en-aut-sei=Nagase
en-aut-mei=Isamu
kn-aut-name=長瀬勇
kn-aut-sei=長瀬
kn-aut-mei=勇
aut-affil-num=2
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部産婦人科教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部産婦人科教室
END
start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=1
article-no=
start-page=115
end-page=120
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=On the Primary Mortality due to the Radiotherapy in Carcinoma of the Cervix (Data of 21 years from 1934 to 1954 at the Dept. of Obstetrics and Gynecology, Okayama University)
kn-title=子宮頸癌放射線療法に於ける一次死亡について(岡大婦人科昭和9〜29年の21年間成績)
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=1) There were 67 primary mortalities out of 1,974 cases of the cervical carcinoma who were treated by radiation at the Dept. of Obstetrics and Gynecology, Okayama University, during the recent 21 years (average primary mortality: 3.4%) 2) The first cause of death is infection which has greater part of primary mortality, and peritonitis is dominant. The second cause of death is bleeding and the third is death from the advanced cachexia. 3) From 1934 to 1951, we generally gave them radiumtherapy after roentogentherapy and primary death occurred more frequently at the time of radiumtherapy than at roentogentherapy. From 1952, radiotherapy has been performed by Yagi-Takeda's method which had no influences on the primary mortality. 4) Primary mortality increases with the progress of the clinical stage of carcinoma and is 1.3% in the I & II stage, while 4.3% in the III & IV stage. The primary mortality has no relations to the site of the carcinoma, the ages and the frequency of parturition of the patients. Primary mortality was remarkably high during and within a few years after the World War II.
en-copyright=
kn-copyright=
en-aut-name=HiraiSakae
en-aut-sei=Hirai
en-aut-mei=Sakae
kn-aut-name=平井栄
kn-aut-sei=平井
kn-aut-mei=栄
aut-affil-num=1
ORCID=
en-aut-name=SarataniKazuo
en-aut-sei=Saratani
en-aut-mei=Kazuo
kn-aut-name=更谷一夫
kn-aut-sei=更谷
kn-aut-mei=一夫
aut-affil-num=2
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部産婦人科教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部産婦人科教室
END
start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=1
article-no=
start-page=109
end-page=113
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=On the Effect of Catalytic Function of Liver-amylase Jrradiated with X-rays
kn-title=摘出臟器(肝臓)のAmylaseに及ぼす「レ」線の影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The various metabolism are carried out in living cells and the relevance of enzyme research is based upon the idea that the chemical reactions that occur in living cells from the core of life itself. But the biochemical metabolism is affected by X-rays irradiation, and so we think that X-rays irradiation effect upon the catalytic function of the enzyme, and we experimented whether X-rays irradiation effect on the catalytic function of Amylase in cells of liver which is extracted without bacilli, or not. And then we find out that the irradiation with 60r rised the catalytic function of Amylase the irradiation with 200r, 400r repressed the catalytic function of Amylase.
en-copyright=
kn-copyright=
en-aut-name=ShiragaK.
en-aut-sei=Shiraga
en-aut-mei=K.
kn-aut-name=白髮克也
kn-aut-sei=白髮
kn-aut-mei=克也
aut-affil-num=1
ORCID=
en-aut-name=SadatoshiK.
en-aut-sei=Sadatoshi
en-aut-mei=K.
kn-aut-name=貞利庫司
kn-aut-sei=貞利
kn-aut-mei=庫司
aut-affil-num=2
ORCID=
en-aut-name=MorimotoY.
en-aut-sei=Morimoto
en-aut-mei=Y.
kn-aut-name=森本義樹
kn-aut-sei=森本
kn-aut-mei=義樹
aut-affil-num=3
ORCID=
en-aut-name=NishishitaS.
en-aut-sei=Nishishita
en-aut-mei=S.
kn-aut-name=西下創一
kn-aut-sei=西下
kn-aut-mei=創一
aut-affil-num=4
ORCID=
en-aut-name=YasudaM.
en-aut-sei=Yasuda
en-aut-mei=M.
kn-aut-name=安田稔
kn-aut-sei=安田
kn-aut-mei=稔
aut-affil-num=5
ORCID=
en-aut-name=HashigamiT.
en-aut-sei=Hashigami
en-aut-mei=T.
kn-aut-name=橋上正
kn-aut-sei=橋上
kn-aut-mei=正
aut-affil-num=6
ORCID=
en-aut-name=NakamuraH.
en-aut-sei=Nakamura
en-aut-mei=H.
kn-aut-name=中村文雄
kn-aut-sei=中村
kn-aut-mei=文雄
aut-affil-num=7
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=2
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=6
en-affil=
kn-affil=岡山大学医学部放射線科
affil-num=7
en-affil=
kn-affil=岡山大学医学部放射線科
END
start-ver=1.4
cd-journal=joma
no-vol=69
cd-vols=
no-issue=1
article-no=
start-page=103
end-page=107
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1957
dt-pub=19570131
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=EFFECT OF RADIOACTIVITY AND THE HEINZ'S BODY (Reference to the Study on the Erythrocytes of the Ship's crews who were injured by the Hydrogen Bomb Experiment at Bikini Atoll on March 1954)
kn-title=放射線とHeinz小体 附. 昭和29年3月ビキニ環礁水爆実験の被害船第5福龍丸船員の赤血球Heinz小体に就て
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=It has been demonstrated that the formation of so-called Heinz's body in erythrocytes could be brought forth by the use of radioactive phosphorous (P(32)) in both vivo and in vitro. The Heinz's body formation was also recognized in erythrocytes in general of the blood obtained from the ship's crews of the Fukuryu Maru who had been subjected to an influence of the hydrogen bomb experimental trialx in Bikini on March 1954, and examined when red blood cells have been suspended in physiological salt solution and left for 6-9 hours in an incubator at the temperature of 37°C. The finding of Heinz's body in the red blood cells of the crews of the above vessel may have been attributed to the lowered functional capacity of the reticuloendothelial system, speaks for erythrocytes susceptible to undergo retrogressive degenerative change.
en-copyright=
kn-copyright=
en-aut-name=YamamotoMichio
en-aut-sei=Yamamoto
en-aut-mei=Michio
kn-aut-name=山本道夫
kn-aut-sei=山本
kn-aut-mei=道夫
aut-affil-num=1
ORCID=
en-aut-name=NishishitaSoichi
en-aut-sei=Nishishita
en-aut-mei=Soichi
kn-aut-name=西下創一
kn-aut-sei=西下
kn-aut-mei=創一
aut-affil-num=2
ORCID=
en-aut-name=HashigamiTadashi
en-aut-sei=Hashigami
en-aut-mei=Tadashi
kn-aut-name=橋上正
kn-aut-sei=橋上
kn-aut-mei=正
aut-affil-num=3
ORCID=
en-aut-name=YamamotoKoki
en-aut-sei=Yamamoto
en-aut-mei=Koki
kn-aut-name=山本弘毅
kn-aut-sei=山本
kn-aut-mei=弘毅
aut-affil-num=4
ORCID=
en-aut-name=KandaMizuho
en-aut-sei=Kanda
en-aut-mei=Mizuho
kn-aut-name=神田瑞穗
kn-aut-sei=神田
kn-aut-mei=瑞穗
aut-affil-num=5
ORCID=
en-aut-name=MimuraKimimasa
en-aut-sei=Mimura
en-aut-mei=Kimimasa
kn-aut-name=三村公正
kn-aut-sei=三村
kn-aut-mei=公正
aut-affil-num=6
ORCID=
en-aut-name=ShigenobuYukio
en-aut-sei=Shigenobu
en-aut-mei=Yukio
kn-aut-name=重信幸男
kn-aut-sei=重信
kn-aut-mei=幸男
aut-affil-num=7
ORCID=
en-aut-name=HamadaNoruo
en-aut-sei=Hamada
en-aut-mei=Noruo
kn-aut-name=浜田稔雄
kn-aut-sei=浜田
kn-aut-mei=稔雄
aut-affil-num=8
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線科教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部放射線科教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線科教室
affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線科教室
affil-num=5
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=6
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=7
en-affil=
kn-affil=岡山大学医学部法医学教室
affil-num=8
en-affil=
kn-affil=岡山大学医学部法医学教室
END
start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=10-2
article-no=
start-page=6745
end-page=6754
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Biological Effect of Radiation on Bacteria Part III On Effect of X-ray Radiation on Morphology of Sal. 57 S
kn-title=放射線の細菌に対する生物効果に関する研究 第3編 X線被照射菌の形態学的観察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Using Sal 57 S as test organism, the author studied the effect of x-ray radiation on the morphology of bacteria by means of electron microscope. The dosis given to the microorganism was 2,000r or 8,000r. The following results were obtained. 1) The morphology of the cells was kept almost normal as just after the irradiation. 2) Prominiently elongated bacteria were found on succeeding cultures of 2, 3 and 5 hrs after the irradiation. 3) There were found some regions that had a low electron density on elongated cell. The distances between the regions were almost normal cell size or somewhat exceeded on its size. With the lapse of cultivation time the region became more distinctive and wider. 4) The bacterial cells cultured following after the irradiation were lost its homogeneousness in part and revealed granule-like structure in its interior and in the sever case the body of cell turned to be a exuviae form. 5) As was found on the cultured cells mentioned above, the identical facts was observed by the bacterial cells stocked in refrigerator for 2 days following after the irradiation.
en-copyright=
kn-copyright=
en-aut-name=KanemasaYasuhiro
en-aut-sei=Kanemasa
en-aut-mei=Yasuhiro
kn-aut-name=金政泰弘
kn-aut-sei=金政
kn-aut-mei=泰弘
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部微生物学教室
END
start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=10-2
article-no=
start-page=6733
end-page=6743
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Biological Effect of Radiation on Bacteria Part II On Effect of X-ray Radiation on Enzyme System of Sal 57 S
kn-title=放射線の細菌に対する生物効果に関する研究 第2編 Sal. 57 Sの酵素系に及ぼすX線照射の影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In order to elucidate the effects of x-ray radiation on enzyme system of bacteria, the author studied the effect of x-ray radiation on enzyme system of Sal 57 S which were irradiated such large dosis as 8,000r in comparison with the enzyme activity of untreated cells. And the following results were obtained. 1) The oxidation of glucose and pyruvate was inhibited to a large extent on the enzyme systm of the x-ray irradiated organisms. And from the findings of the studies on RQ., stoichiometry and action of inhibitors, it could not find any difference on the oxidation pathway from glucose to pyruvate, but on the further oxidation pathway of pyruvate. The inhibition on the further oxidation pathway of pyruvate brought about marked accumulation of acetate in the cells of Sal 57 S irradiated to x-ray. 2) As concerns to the oxidation of member of TCA cycle, an inhibition was found at the oxidation of α-ketoglutalate and also of succinate to a slight extent. 3) The inhibition on the oxidation of glucose, pyruvate and α-ketoglutalate could be removed by addition of cysteine. From the view of this fact, the inhibition was supposed to be occured in the enzyme system relating to -SH group. 4) The effect of x-ray irradiation on oxydative phosphorylation was studied by measuring P:O ratio and P(32) incorporation into Δ-7-p. The decrease of P:O ratio and P(32) incorporation was observed. This fact possibly implied that the irradiation of x-ray acted as an uncoupler on oxydative phosphorylation 5) There was not observed any changes on the nucleic acids system of bacteria just after the x-ray irradiation. However, amount of DNA showed a decrease by a succeeding incubation of the organism after x-ray irradiation. An inhibition to the incorporation of phosphorus into DNA fraction was also proved on the cells by isotopic study using P(32).
en-copyright=
kn-copyright=
en-aut-name=KanemasaYasuhiro
en-aut-sei=Kanemasa
en-aut-mei=Yasuhiro
kn-aut-name=金政泰弘
kn-aut-sei=金政
kn-aut-mei=泰弘
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部微生物学教室
END
start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=10-2
article-no=
start-page=6723
end-page=6732
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590930
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on Biological Effect of Radiation on Bacteria Part I On Lethal Effect of X-ray Radiation on Sal 57 S
kn-title=放射線の細菌に対する生物効果に関する研究 第1編 Sal. 57 Sに対するX線照射の致死効果について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Using Sal 57 S as test organism, the author studied biological effect of x-ray radiation by observing the lethal effect under various conditions, in which the state of the organism at irradiation, the properties of the material that gives secondary ray and the dosis of radiation were studied in different combinations. The lethal effect mentioned above was measured by enumeration of surviving cells and the following results were obtained. 1) The surviving curve obtained by the irradiation on cell suspension of the microorganisms could be represented in an exponential curve. In this study, several kinds of solutions were examined using as the liquid media of the bacterial suspension, i. e. normal saline, phosphate buffer, Fe++ added normal saline and Mg++ added normal saline. The survival rates obtained on each suspension were not different to a significant degree. However, the survival rate was somewhat decreased at the examination on the suspension into which platine wire was submerged. 2) The survival rates obtained by the x-ray irradiation on cell suspensions in different concentrations were quite the same on either suspensions. However, in comparative study between the irradiation on a homogeneous cell suspension, and that on unhomogeneous cell suspension, the later showed a higher survival rate. 3) The surviving curve obtained by the irradiation on a spreaded growth on the entire surface of nutrient agar was also repesentable by exponential curve. An application of lead plate as the material which gives secondary ray showed prominient reinforcement of lethal effect. The surviving curve vas deviated from the original curve to a downward concaved curve on semi-log co-ordinates. 4) The lethal effect to dry cells was inferior than that to wet cells and also the effect was reinforced by an application of lead plate as material which gives secondary ray. 5) The reinforcement of lethal effect by secondary ray was studied using several materials as the emitter for secondary ray. In this study the effect was determined by means of the growth observed on nutrient agar plate. As the result of this study, the effect of reinforcement came in following order Pb, Cu, Al then wooden plate; this order was the same as atomic numbers. The scondary ray could be easily intercepted even by a sheet of paper, acordingly, the lethal effect by the secondary ray was markedly decreased as an increase of the distance between the emitter and the surface of madia.
en-copyright=
kn-copyright=
en-aut-name=KanemasaYasuhiro
en-aut-sei=Kanemasa
en-aut-mei=Yasuhiro
kn-aut-name=金政泰弘
kn-aut-sei=金政
kn-aut-mei=泰弘
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部微生物学教室
END
start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=6-2
article-no=
start-page=3393
end-page=3402
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590515
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Serological Studies on Radiation Injuries Part III Influence of X-Irradiation upon Reverse-anaphylaxis with Forssman's Antibody
kn-title=放射線障害の血清学的研究 第III編 Forssman氏抗体による逆過敏症に及ぼすX線の影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Forssman's antibody was obtained from rabbits by injecting 10 percent saline emulsion of guinea pig kidney seven times every four day.
The minimum lethal dose of Forssman's antibody was administered into guinea pigs after the whole body X-irradiation. The effect of the irradiation on the lethality, the time to the death, the reduction rate of the complement, weight of the lung and clinical signs were investigated. The results were as follows: 1) By 200r irradiation, the reverse-anaphylaxis of guinea pigs by Forssman's antibody was restrained, and the lethal minimum dose was highest around the 14th day, and gradually returned to normal around the 21st day. 2) By 200r iradiation, the period of incubation until the typical shock of reverseanaphylaxis and the duration until the death by shock were prolonged. 3) By 200r irradiation, the lung-weight showed a tendency to be lightened in comparison with the control group. 4) By X-irradiation below 100r, no typical view was found, but it seemed to have the same tendency with the 200r exposure as a whole.
en-copyright=
kn-copyright=
en-aut-name=MurakamiSadao
en-aut-sei=Murakami
en-aut-mei=Sadao
kn-aut-name=村上貞夫
kn-aut-sei=村上
kn-aut-mei=貞夫
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部衛生学教室
END
start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=6-2
article-no=
start-page=3381
end-page=3392
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590515
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Serological Studies on Radiation Injuries Part II Influence of X-Irradiation upon Passive Skin-Anaphylaxis
kn-title=放射線障害の血清学的研究 第II編 被働性皮膚過敏症に及ぼすX線の影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Guinea pigs were sensitized with anti-egg-albumin rabbit serum with various intervals after the whole body x-irradiation. Twenty-four hours later 0.1cc of antigen of 1, 0.1, 0.01 and 0.001% were injected on the abdominal skin intracutaneously. Arthus' phenomenon was observed after twenty four hours. The results were as follows: 1) By 200r x-irradiation, Arthus' phenomenon was mostly restrained on the 7th day after the exposure and returned to normal later but showed a tendency to incraese on the 28th day. The area of skin-redness at Arthus' phenomenon became small on the 7th day after exposure, and returned to normal later but showed a tendency to enlarge on the 28th day after the exposure. 2) By 400r irradiation, Arthus' phenomenon was mostly restrained on the 7th day and the area of skin-redness was scarecely observed. 3) Arthus' phenomenon by the method with Evans-blue injected intraveously as an index showed the largest area of the skincolouring on the 7th day after 200r x-irradiation without showing any clear margin. It returned normal afterwards. On the 28th day, the area of the skin-colouring was small with a clear margin. 4) After the 200r exposure, while the epidermis group was atrophic, pathological changes of skin were not so marked in general.
en-copyright=
kn-copyright=
en-aut-name=MurakamiSadao
en-aut-sei=Murakami
en-aut-mei=Sadao
kn-aut-name=村上貞夫
kn-aut-sei=村上
kn-aut-mei=貞夫
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部衛生学教室
END
start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=6-2
article-no=
start-page=3371
end-page=3380
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590515
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Serological Studies on Radiation Injuries Part 1 Influence of X-Irradiation upon Passive Anaphylaxis
kn-title=放射線障害の血清学的研究 第1編 被働性過敏症に及ぼすX線の影響について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Hybrid guinea pigs weighing about 300grams were used for the test. Egg-album in antiserum was injected immediately after the whole body irradiation of X-ray. The same was done on the 5th, 7th, 14th, 21st and the 28th days. Twenty four hours later, the antigen was administered to observe the passive anaphylactic shock. The results were as follows: 1) The passive anaphylactic shock was restrained 5-7 days after the x-irradiation of 200r. It returned to normal after 14 days. After 28 days the reaction seemed to turn stronger. 2) By x-irradiation of 200r, the time of incubation to typical shock showed a tendency to prolong. The duration to death by shock also seemed to prolong. 3) Concerning the reduction-rate of the compliment no particular result was obtained. 4) The drop of body temperature was uncertain in case of 200r irradiation. 5) The dilation of the lung after the shock in guinea pigs has a mortal effect. By 200r irradiation, the lung dilation was moderate on the 7th day after the irradiation. 6) As for the clinical signs after 200r irradiation, no serious condition showed on the 7th day. The condition on the 5th day succeeded while they advanced after the 14th, the 21st and the 28th days. 7) After the 7th day of irradiation, the anaphylaxis of guinea pigs did not appear apparently in 100r irradiation but showed stronger in case of 50r and 25r irradiation.
Thus the author concludes that the effect of irradiation on the serological reactivity of guinea pigs was mostly restrained around one week after the irradiation in case of passive anaphylaxis by egg-albumin antibody as an indicator.
en-copyright=
kn-copyright=
en-aut-name=MurakamiSadao
en-aut-sei=Murakami
en-aut-mei=Sadao
kn-aut-name=村上貞夫
kn-aut-sei=村上
kn-aut-mei=貞夫
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部衛生学教室
END
start-ver=1.4
cd-journal=joma
no-vol=71
cd-vols=
no-issue=6-2
article-no=
start-page=3193
end-page=3196
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1959
dt-pub=19590515
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Experimental Studies on the Nature of Radiation Disturbances Part 2 A anemize substance which is produced in the peripheral blood with X-ray or Co(60)irradiation
kn-title=放射線障害の本態に関する実験的研究 第2編 催貧血に就いて
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=We attempted to reserch that a poison are produced in blood when the blood are irradiated, and whether such poison causes tissue injuries secondarily or not. Experimental Method: After the rabbits blood of removing serum in test tube are irradiated with great doses of X-rays or Co(60) at a time, such blood injected to other healthy rabbits, and then we research to what change are brought in such case, and we find out following matter. Experimental Results: The peripheral blood cell count reduced after transfusions, the function of the reticuloendotherial system falled and the apperance of Heinz's body erythrocytes were remarkable. In view of these facts, it seems to be produced a toxic substance in the peripheral blood of the rabbit irradiated with X-ray or Co(60), and the the toxic substance causes radiation injuries secondarily.
en-copyright=
kn-copyright=
en-aut-name=YamamotoM.
en-aut-sei=Yamamoto
en-aut-mei=M.
kn-aut-name=山本道夫
kn-aut-sei=山本
kn-aut-mei=道夫
aut-affil-num=1
ORCID=
en-aut-name=NishishitaS.
en-aut-sei=Nishishita
en-aut-mei=S.
kn-aut-name=西下創一
kn-aut-sei=西下
kn-aut-mei=創一
aut-affil-num=2
ORCID=
en-aut-name=AndoR.
en-aut-sei=Ando
en-aut-mei=R.
kn-aut-name=安東龍
kn-aut-sei=安東
kn-aut-mei=龍
aut-affil-num=3
ORCID=
en-aut-name=NobukiS.
en-aut-sei=Nobuki
en-aut-mei=S.
kn-aut-name=信木茂生
kn-aut-sei=信木
kn-aut-mei=茂生
aut-affil-num=4
ORCID=
en-aut-name=KojimaS.
en-aut-sei=Kojima
en-aut-mei=S.
kn-aut-name=小島澄一
kn-aut-sei=小島
kn-aut-mei=澄一
aut-affil-num=5
ORCID=
en-aut-name=TanimotoJ.
en-aut-sei=Tanimoto
en-aut-mei=J.
kn-aut-name=谷本潤一
kn-aut-sei=谷本
kn-aut-mei=潤一
aut-affil-num=6
ORCID=
en-aut-name=AkagiK.
en-aut-sei=Akagi
en-aut-mei=K.
kn-aut-name=赤木瑩子
kn-aut-sei=赤木
kn-aut-mei=瑩子
aut-affil-num=7
ORCID=
en-aut-name=ShiakuT.
en-aut-sei=Shiaku
en-aut-mei=T.
kn-aut-name=塩飽健
kn-aut-sei=塩飽
kn-aut-mei=健
aut-affil-num=8
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=4
en-affil=
kn-affil=
affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=6
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=7
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=8
en-affil=
kn-affil=岡山大学医学部放射線医学教室
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=11-12
article-no=
start-page=1075
end-page=1079
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198912
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of beautiful bone scan due to bone metastasis of gastric cancer
kn-title=Beautiful Bone Scanを呈した胃癌骨転移の1例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 46-year-old female presented with lumbago. A plain X-ray examination did not indicate any distinctive changes, however a bone scintigram showed beautiful bone scan. A bone marrow biopsy certified metastatic adenocarcinoma and a primary gastric carcinoma was discovered subsequently. Beautiful bone scan can be seen in malignant metastasis, several bone metabolic diseases and other rare cases. A rare case of a gastric cancer exhibiting a beautiful bone scan, is described.
en-copyright=
kn-copyright=
en-aut-name=KurodaMasahiro
en-aut-sei=Kuroda
en-aut-mei=Masahiro
kn-aut-name=黒田昌宏
kn-aut-sei=黒田
kn-aut-mei=昌宏
aut-affil-num=1
ORCID=
en-aut-name=TanakaAkio
en-aut-sei=Tanaka
en-aut-mei=Akio
kn-aut-name=田中朗雄
kn-aut-sei=田中
kn-aut-mei=朗雄
aut-affil-num=2
ORCID=
en-aut-name=YamamotoYoshio
en-aut-sei=Yamamoto
en-aut-mei=Yoshio
kn-aut-name=山本淑雄
kn-aut-sei=山本
kn-aut-mei=淑雄
aut-affil-num=3
ORCID=
en-aut-name=SimizuMitsuharu
en-aut-sei=Simizu
en-aut-mei=Mitsuharu
kn-aut-name=清水光春
kn-aut-sei=清水
kn-aut-mei=光春
aut-affil-num=4
ORCID=
en-aut-name=SatoNobuo
en-aut-sei=Sato
en-aut-mei=Nobuo
kn-aut-name=佐藤伸夫
kn-aut-sei=佐藤
kn-aut-mei=伸夫
aut-affil-num=5
ORCID=
en-aut-name=JojaIkuo
en-aut-sei=Joja
en-aut-mei=Ikuo
kn-aut-name=上者郁夫
kn-aut-sei=上者
kn-aut-mei=郁夫
aut-affil-num=6
ORCID=
en-aut-name=HashimotoKeiji
en-aut-sei=Hashimoto
en-aut-mei=Keiji
kn-aut-name=橋本啓二
kn-aut-sei=橋本
kn-aut-mei=啓二
aut-affil-num=7
ORCID=
en-aut-name=HirakiYoshio
en-aut-sei=Hiraki
en-aut-mei=Yoshio
kn-aut-name=平木祥夫
kn-aut-sei=平木
kn-aut-mei=祥夫
aut-affil-num=8
ORCID=
en-aut-name=NakadaHiroyuki
en-aut-sei=Nakada
en-aut-mei=Hiroyuki
kn-aut-name=仲田浩之
kn-aut-sei=仲田
kn-aut-mei=浩之
aut-affil-num=9
ORCID=
en-aut-name=KibataMasayoshi
en-aut-sei=Kibata
en-aut-mei=Masayoshi
kn-aut-name=木畑正義
kn-aut-sei=木畑
kn-aut-mei=正義
aut-affil-num=10
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=2
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=6
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=7
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=8
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=9
en-affil=
kn-affil=国立療養所南岡山病院内科
affil-num=10
en-affil=
kn-affil=国立療養所南岡山病院内科
en-keyword=Beautiful Bone Scan
kn-keyword=Beautiful Bone Scan
en-keyword=胃癌
kn-keyword=胃癌
en-keyword=骨転移
kn-keyword=骨転移
en-keyword=播種性骨髄癌症
kn-keyword=播種性骨髄癌症
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=5-6
article-no=
start-page=495
end-page=503
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198906
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Metallothionein messenger RNA regulation in the macular mutant mouse: An animal model of Menkes's kinky-hair disease
kn-title=Menkes症モデルマウス (Macular mouse) でのMetallothionein mRNAの調節
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=MT-mRNA levels in tissue were measured in normal and macular mutant mice. The MT-mRNA level in tissues (kidney, intestine, liver, brain, spleen, thymus, lung and heart) of 7-day-old mutants was not changed compared to normal mice. Kidney MT-mRNA levels in the mutant foetus at 18 days of gestation and in the 3- and 7-day-old mutant were not changed compared compared to normal mice, with the exception of the 1-day-old mutant. Intestine and liver MT-mRNA levels in the mutant foetus at 18 days gestation and in the 1-, 3- and 7-day-old mutant were not changed compared to normal mice.
en-copyright=
kn-copyright=
en-aut-name=KajiMitsumasa
en-aut-sei=Kaji
en-aut-mei=Mitsumasa
kn-aut-name=加地充昌
kn-aut-sei=加地
kn-aut-mei=充昌
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室
en-keyword=Menkes's kinky-hair disease
kn-keyword=Menkes's kinky-hair disease
en-keyword=Metallothionein mRNA
kn-keyword=Metallothionein mRNA
en-keyword=Copper
kn-keyword=Copper
en-keyword=Kidney
kn-keyword=Kidney
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=3-4
article-no=
start-page=315
end-page=325
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198904
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Modification of intracellular uptake and killing effect of Adriamycin (ADR) by cepharanthine on ADR resistant Ehrlich ascites tumor cells
kn-title=Ehrlich腹水癌細胞の薬剤耐性細胞における温熱によるAdriamycinの効果増強とその修飾
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Adriamycin (ADR) is a well known anticancer agent which is frequently used alone or combination with other anticancer agents. An ADR-resistant cell line derived from Ehrlich ascites tumor cells (EATC) was established in our laboratory. In this report, differences between wild EATC and ADR resistant EATC were studied. The intracellular ADR uptake increased at a temperature (41.0°C) that had a little effect on the viability of wild EATC. The intracellular ADR uptake of ADR-resistant EATC also increased at elevated temperature (41.0°C). However, ADR resistant EATC had an enhanced acquired capacity that increased the efflux of intracellular ADR. Cepharanthine (CP), 1mcg/ml, inhibited the efflux of intracellular ADR and maintained the retention of ADR at high levels in cells from both cell lines, so the killing effects were enhanced with a combination ADR and CP. From these results, the mechanisms of resistance to ADR may be discussed. The killing effects of ADR depend on intracellular ADR uptake, retention and maintenance. Hyperthermic treatment accelerates the influx of ADR. In addition, CP suppresses the efflux of intracellular ADR, and increased markedly the cytotoxic effect of ADR on ADR resistant EATC. The combination of ADR, CP and hyperthermia may be effective and useful therapy to overcome ADR-resistant cancer cells.
en-copyright=
kn-copyright=
en-aut-name=KashitaniNaoko
en-aut-sei=Kashitani
en-aut-mei=Naoko
kn-aut-name=柏谷尚子
kn-aut-sei=柏谷
kn-aut-mei=尚子
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室
en-keyword=Ehrlich腹水癌細胞
kn-keyword=Ehrlich腹水癌細胞
en-keyword=Adriamycin
kn-keyword=Adriamycin
en-keyword=Hyperthermia
kn-keyword=Hyperthermia
en-keyword=Multidrug resistance
kn-keyword=Multidrug resistance
en-keyword=Flow cytometry
kn-keyword=Flow cytometry
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=3-4
article-no=
start-page=303
end-page=314
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198904
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Modification by hyperthermia and cepharanthine of the Killing effect of adriamycin on NIH 3T3 cells
kn-title=Adriamycinの殺細胞効果の加温およびCepharanthineによる修飾
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The cytotoxic effect of anticancer agents depends markedly on the intracellular uptake of the anticancer drug; its maintenance is increased by accelerating the intracellular uptake of anticancer agent and inchbiting. Using with flow-cytometry, we demonstrated that the intracellular uptake of adriamycin (ADM) is increased by hyperthermia, and that cepharanthine (CEP) and Verapamil inhibit its retention. We investigated the cytotoxic effect of the combination of ADR, CEP and hyperthermia, using a NIH3T3 cell line. The cytotoxic effect of ADR is increased by hyperthermia; its effect is acquired at a lower temperature which has no cytotoxic effect alone. With the conbination of CEP, ADR and hyperthermia, the cytotoxic effect is further increased. The synergism is increased by the elevation of temperature and a long of exposure time of CEP. The increase of the intracellular accumulation anticanceragent is important to overcome multidrugresistance, a phenomenon which has that attracted agreat deal of attention.
en-copyright=
kn-copyright=
en-aut-name=MizutaAkifumi
en-aut-sei=Mizuta
en-aut-mei=Akifumi
kn-aut-name=水田昭文
kn-aut-sei=水田
kn-aut-mei=昭文
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室
en-keyword=Adriamycin
kn-keyword=Adriamycin
en-keyword=cepharantine
kn-keyword=cepharantine
en-keyword=加温
kn-keyword=加温
en-keyword=殺細胞効果
kn-keyword=殺細胞効果
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=3-4
article-no=
start-page=295
end-page=302
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198904
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Improvement of head magnetic resonance image quality
kn-title=頭部MRI像の画質改善について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The purpose of this study is to present a method of boundary enhancement algorithms for magnetic resonance images using a V-filter and clinical applications. By iterated V-filtering, the signal-to-noise ratio can be increased with preservation of edge sharpness. This is due to the relationship of the signal-to-noise ratio to the mean-to-variance ratio. These techniques were applied to clinical cases using MRI in the evaluation of the brain tumor. The boundaries of the brain tumor and the edematous region were precisely extracted.
en-copyright=
kn-copyright=
en-aut-name=KanzakiNoriko
en-aut-sei=Kanzaki
en-aut-mei=Noriko
kn-aut-name=神崎典子
kn-aut-sei=神崎
kn-aut-mei=典子
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室
en-keyword=V-filter
kn-keyword=V-filter
en-keyword=MRI
kn-keyword=MRI
en-keyword=Boundary enhancement
kn-keyword=Boundary enhancement
en-keyword=Edematous region
kn-keyword=Edematous region
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=87
end-page=96
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical evaluation of stereoscopic DSA for vascular lesions
kn-title=脳血管性病変におけるステレオDSAの臨床的評価
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Seventy-one series of stereoscopic DSA utilized on thirty-nine patients with intracranial vascular lesions were evaluated by comparison with subtracted magnified angiograms or independently. All stereoscopic series had good or fairly good stereoscopic quality. Stereoscopic DSA was useful in the preoperative stereoscopic vascular analysis of vascular lesions such as aneurysms, arteriovenous malformations, cartotid-cavernous fistulas, obstructive or stenotic vascular lesions and vascular elongations. Stereoscopic DSA was also useful for evaluation of the post-operative or post-embolization states of these vascular lesions. We think that stereoscopic DSA can replace many areas of conventional angiography for vascular lesions in the near future.
en-copyright=
kn-copyright=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=1
ORCID=
en-aut-name=KojimaKanji
en-aut-sei=Kojima
en-aut-mei=Kanji
kn-aut-name=児島完治
kn-aut-sei=児島
kn-aut-mei=完治
aut-affil-num=2
ORCID=
en-aut-name=KageyamaJunichi
en-aut-sei=Kageyama
en-aut-mei=Junichi
kn-aut-name=影山淳一
kn-aut-sei=影山
kn-aut-mei=淳一
aut-affil-num=3
ORCID=
en-aut-name=HinoIchiroh
en-aut-sei=Hino
en-aut-mei=Ichiroh
kn-aut-name=日野一郎
kn-aut-sei=日野
kn-aut-mei=一郎
aut-affil-num=4
ORCID=
en-aut-name=TakashimaHitoshi
en-aut-sei=Takashima
en-aut-mei=Hitoshi
kn-aut-name=高島均
kn-aut-sei=高島
kn-aut-mei=均
aut-affil-num=5
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=6
ORCID=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=7
ORCID=
en-aut-name=OhmotoTakashi
en-aut-sei=Ohmoto
en-aut-mei=Takashi
kn-aut-name=大本尭史
kn-aut-sei=大本
kn-aut-mei=尭史
aut-affil-num=8
ORCID=
en-aut-name=UedaKiyotaka
en-aut-sei=Ueda
en-aut-mei=Kiyotaka
kn-aut-name=植田清隆
kn-aut-sei=植田
kn-aut-mei=清隆
aut-affil-num=9
ORCID=
en-aut-name=FujiwaraTakashi
en-aut-sei=Fujiwara
en-aut-mei=Takashi
kn-aut-name=藤原敬
kn-aut-sei=藤原
kn-aut-mei=敬
aut-affil-num=10
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学脳神経外科学教室
affil-num=9
en-affil=
kn-affil=香川医科大学脳神経外科学教室
affil-num=10
en-affil=
kn-affil=香川医科大学脳神経外科学教室
en-keyword=ステレオDSA
kn-keyword=ステレオDSA
en-keyword=脳血管性病変
kn-keyword=脳血管性病変
en-keyword=動脈瘤
kn-keyword=動脈瘤
en-keyword=動静脈奇形
kn-keyword=動静脈奇形
en-keyword=モヤモヤ病
kn-keyword=モヤモヤ病
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=77
end-page=86
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Clinical evaluation of stereoscopic DSA for brain tumors
kn-title=脳腫瘍におけるステレオDSAの臨床的評価
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Ninety-six series of stereoscopic DSA utilized on forty-eight brain tumor patients were evaluated by comparison with subtracted magnified angiograms or independently. All stereoscopic DSA series had good or fairly good stereoscopic quality. Stereoscopic DSA was useful for the pre-operative diagnosis of brain tumors, such as menigniomas, pituitary adenomas, glioblastomas, neurinomas, etc. Stereoscopic DSA was also useful for the evaluation of the post-operative states of these brain tumors. In the near future, stereoscopic DSA may replace many areas of conventional angiography for the diagnosis of brain tumors.
en-copyright=
kn-copyright=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=1
ORCID=
en-aut-name=KojimaKanji
en-aut-sei=Kojima
en-aut-mei=Kanji
kn-aut-name=児島完治
kn-aut-sei=児島
kn-aut-mei=完治
aut-affil-num=2
ORCID=
en-aut-name=KageyamaJunichi
en-aut-sei=Kageyama
en-aut-mei=Junichi
kn-aut-name=影山淳一
kn-aut-sei=影山
kn-aut-mei=淳一
aut-affil-num=3
ORCID=
en-aut-name=HinoIchiroh
en-aut-sei=Hino
en-aut-mei=Ichiroh
kn-aut-name=日野一郎
kn-aut-sei=日野
kn-aut-mei=一郎
aut-affil-num=4
ORCID=
en-aut-name=TakashimaHitoshi
en-aut-sei=Takashima
en-aut-mei=Hitoshi
kn-aut-name=高島均
kn-aut-sei=高島
kn-aut-mei=均
aut-affil-num=5
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=6
ORCID=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=7
ORCID=
en-aut-name=OhmotoTakashi
en-aut-sei=Ohmoto
en-aut-mei=Takashi
kn-aut-name=大本尭史
kn-aut-sei=大本
kn-aut-mei=尭史
aut-affil-num=8
ORCID=
en-aut-name=UedaKiyotaka
en-aut-sei=Ueda
en-aut-mei=Kiyotaka
kn-aut-name=植田清隆
kn-aut-sei=植田
kn-aut-mei=清隆
aut-affil-num=9
ORCID=
en-aut-name=MinoShogo
en-aut-sei=Mino
en-aut-mei=Shogo
kn-aut-name=三野章呉
kn-aut-sei=三野
kn-aut-mei=章呉
aut-affil-num=10
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学脳神経外科学教室
affil-num=9
en-affil=
kn-affil=香川医科大学脳神経外科学教室
affil-num=10
en-affil=
kn-affil=香川医科大学脳神経外科学教室
en-keyword=ステレオDSA
kn-keyword=ステレオDSA
en-keyword=脳腫瘍
kn-keyword=脳腫瘍
en-keyword=髄膜腫
kn-keyword=髄膜腫
en-keyword=下垂体腺腫
kn-keyword=下垂体腺腫
en-keyword=多形性膠芽腫
kn-keyword=多形性膠芽腫
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=71
end-page=76
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of xanthogranulomatous cholecystitis
kn-title=黄色肉芽腫性胆嚢炎の1例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A case was presented of xanthogranulomatous cholecystitis which resembled carcinoma of the gallbladder on ultrasonography (US) and CT. The findings of US and CT showed a markedly thick-walled gallbladder with poor definition of boundaries which was similar to the infiltration of carcinoma of the gallbladder. Although a rare entity, xanthogranulomatous cholecystitis should be considered in the differential diagnosis of carcinoma of the gallbladder.
en-copyright=
kn-copyright=
en-aut-name=KojimaKanji
en-aut-sei=Kojima
en-aut-mei=Kanji
kn-aut-name=児島完治
kn-aut-sei=児島
kn-aut-mei=完治
aut-affil-num=1
ORCID=
en-aut-name=MoriYasutane
en-aut-sei=Mori
en-aut-mei=Yasutane
kn-aut-name=森泰胤
kn-aut-sei=森
kn-aut-mei=泰胤
aut-affil-num=2
ORCID=
en-aut-name=GohdaFuminori
en-aut-sei=Gohda
en-aut-mei=Fuminori
kn-aut-name=合田文則
kn-aut-sei=合田
kn-aut-mei=文則
aut-affil-num=3
ORCID=
en-aut-name=KawasakiYukiko
en-aut-sei=Kawasaki
en-aut-mei=Yukiko
kn-aut-name=川崎幸子
kn-aut-sei=川崎
kn-aut-mei=幸子
aut-affil-num=4
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=5
ORCID=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=6
ORCID=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=7
ORCID=
en-aut-name=KohmotoTomoji
en-aut-sei=Kohmoto
en-aut-mei=Tomoji
kn-aut-name=河本知二
kn-aut-sei=河本
kn-aut-mei=知二
aut-affil-num=8
ORCID=
en-aut-name=TanakaSatoshi
en-aut-sei=Tanaka
en-aut-mei=Satoshi
kn-aut-name=田中聰
kn-aut-sei=田中
kn-aut-mei=聰
aut-affil-num=9
ORCID=
en-aut-name=KobayashiShohji
en-aut-sei=Kobayashi
en-aut-mei=Shohji
kn-aut-name=小林省二
kn-aut-sei=小林
kn-aut-mei=省二
aut-affil-num=10
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学第一外科学教室
affil-num=9
en-affil=
kn-affil=香川医科大学第一外科学教室
affil-num=10
en-affil=
kn-affil=香川医科大学第一病理学教室
en-keyword=胆嚢炎
kn-keyword=胆嚢炎
en-keyword=黄色肉芽腫性胆嚢炎
kn-keyword=黄色肉芽腫性胆嚢炎
en-keyword=慢性胆嚢炎
kn-keyword=慢性胆嚢炎
en-keyword=CT
kn-keyword=CT
en-keyword=超音波
kn-keyword=超音波
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=65
end-page=69
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Pulmonary artery in the region supplied by daughter branches
kn-title=娘枝領域の肺動脈分岐について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The branching pattern of the pulmonary artery was examined in the autopsied right lung of a 76-year-male, (inflated and fixed lung), in the regions supplied by daughter branches. Ordinarily, the pulmonary arteries are accompanied by the bronchi, but not necessarily by the daughter bronchi. There were two types of branching patterns of the pulmonary artery in the regions be occupied by daughter branches. In one, the pulmonary artery was not accompanied by the daughter bronchi at the beginning of the branch, but was accompanied by the daughter branch in peripheral regions. In the other, some branches of pulmonary artery distributed to the hilar region from neighbouring daughter branch areas. It is very important to consider daughter branches of the pulmonary artery as well as the inherent structure of the lung.
en-copyright=
kn-copyright=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=1
ORCID=
en-aut-name=SatohKatashi
en-aut-sei=Satoh
en-aut-mei=Katashi
kn-aut-name=佐藤功
kn-aut-sei=佐藤
kn-aut-mei=功
aut-affil-num=2
ORCID=
en-aut-name=KageyamaJunichi
en-aut-sei=Kageyama
en-aut-mei=Junichi
kn-aut-name=影山淳一
kn-aut-sei=影山
kn-aut-mei=淳一
aut-affil-num=3
ORCID=
en-aut-name=TsuuchiYasuhiko
en-aut-sei=Tsuuchi
en-aut-mei=Yasuhiko
kn-aut-name=津内保彦
kn-aut-sei=津内
kn-aut-mei=保彦
aut-affil-num=4
ORCID=
en-aut-name=ToyamaYoshihiro
en-aut-sei=Toyama
en-aut-mei=Yoshihiro
kn-aut-name=外山芳弘
kn-aut-sei=外山
kn-aut-mei=芳弘
aut-affil-num=5
ORCID=
en-aut-name=MoriYasutane
en-aut-sei=Mori
en-aut-mei=Yasutane
kn-aut-name=森泰胤
kn-aut-sei=森
kn-aut-mei=泰胤
aut-affil-num=6
ORCID=
en-aut-name=YodenMidori
en-aut-sei=Yoden
en-aut-mei=Midori
kn-aut-name=余田みどり
kn-aut-sei=余田
kn-aut-mei=みどり
aut-affil-num=7
ORCID=
en-aut-name=KawaseYoshirou
en-aut-sei=Kawase
en-aut-mei=Yoshirou
kn-aut-name=川瀬良郎
kn-aut-sei=川瀬
kn-aut-mei=良郎
aut-affil-num=8
ORCID=
en-aut-name=MizukawaKiichiro
en-aut-sei=Mizukawa
en-aut-mei=Kiichiro
kn-aut-name=水川帰一郎
kn-aut-sei=水川
kn-aut-mei=帰一郎
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=9
en-affil=
kn-affil=香川医科大学放射線医学教室
en-keyword=daughter branch
kn-keyword=daughter branch
en-keyword=inflated and fixed lung
kn-keyword=inflated and fixed lung
en-keyword=pulmonary artery
kn-keyword=pulmonary artery
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=61
end-page=64
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of miliary tuberculosis complicating tuberculous meningitis
kn-title=結核性髄膜炎と肺粟粒結核が同時に認められた1症例
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 50 years old housewife presented with complaints of headache and fever. The chest radiograph revealed fine granular shadews in both lung fields on admission. Further examinations were performed including CT and a diagnosis of miliary tuberculosis was made. A few days after admission, neck stiffness, headache, Kernig's sign and other neurological signs rapidly appeared. Tubercle bacillus was detected from the spinal fluid, and a diagsosis of tuberculous meningitis was made. Anti-tuberculous therapy was quickly started, and she had recovered completely 6 months after beginning therapy.
en-copyright=
kn-copyright=
en-aut-name=KawaseYoshiroh
en-aut-sei=Kawase
en-aut-mei=Yoshiroh
kn-aut-name=川瀬良郎
kn-aut-sei=川瀬
kn-aut-mei=良郎
aut-affil-num=1
ORCID=
en-aut-name=SatohKatashi
en-aut-sei=Satoh
en-aut-mei=Katashi
kn-aut-name=佐藤功
kn-aut-sei=佐藤
kn-aut-mei=功
aut-affil-num=2
ORCID=
en-aut-name=MoriYasutane
en-aut-sei=Mori
en-aut-mei=Yasutane
kn-aut-name=森泰胤
kn-aut-sei=森
kn-aut-mei=泰胤
aut-affil-num=3
ORCID=
en-aut-name=ToyamaYoshihiro
en-aut-sei=Toyama
en-aut-mei=Yoshihiro
kn-aut-name=外山芳弘
kn-aut-sei=外山
kn-aut-mei=芳弘
aut-affil-num=4
ORCID=
en-aut-name=SakamotoKazuhiro
en-aut-sei=Sakamoto
en-aut-mei=Kazuhiro
kn-aut-name=坂本和裕
kn-aut-sei=坂本
kn-aut-mei=和裕
aut-affil-num=5
ORCID=
en-aut-name=MizukawaKiichiroh
en-aut-sei=Mizukawa
en-aut-mei=Kiichiroh
kn-aut-name=水川帰一郎
kn-aut-sei=水川
kn-aut-mei=帰一郎
aut-affil-num=6
ORCID=
en-aut-name=TakashimaHitoshi
en-aut-sei=Takashima
en-aut-mei=Hitoshi
kn-aut-name=高島均
kn-aut-sei=高島
kn-aut-mei=均
aut-affil-num=7
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=8
ORCID=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=9
en-affil=
kn-affil=香川医科大学放射線医学教室
en-keyword=結核性髄膜炎
kn-keyword=結核性髄膜炎
en-keyword=肺粟粒結核
kn-keyword=肺粟粒結核
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=53
end-page=59
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Emphysematous cholecystitis - early detection by ultrasonography -
kn-title=気腫性胆嚢炎の1例―超音波診断の重要性―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The ultrasonographic findings in a case of emphysematous cholecystitis were reported. Thick curvilinear high echoes with reverberation and acoustic shadows due to the air were found along the anterior surface of the gall bladder. However, no gas shadow was noted in the right upper abdomen on the plain radiograph. On the following day, an air fluid level in the lumen and a linear gas shadow in the wall of the gall bladder were demonstrated by the plain film and CT. With ultrasonography, it is possible to find small amounts of the air in the gall bladder at an early stage of emphysematous cholecystitis.
en-copyright=
kn-copyright=
en-aut-name=KojimaKanji
en-aut-sei=Kojima
en-aut-mei=Kanji
kn-aut-name=児島完治
kn-aut-sei=児島
kn-aut-mei=完治
aut-affil-num=1
ORCID=
en-aut-name=TsuuchiYasuhiko
en-aut-sei=Tsuuchi
en-aut-mei=Yasuhiko
kn-aut-name=津内保彦
kn-aut-sei=津内
kn-aut-mei=保彦
aut-affil-num=2
ORCID=
en-aut-name=MatsunoShinsuke
en-aut-sei=Matsuno
en-aut-mei=Shinsuke
kn-aut-name=松野慎介
kn-aut-sei=松野
kn-aut-mei=慎介
aut-affil-num=3
ORCID=
en-aut-name=TakashimaHitoshi
en-aut-sei=Takashima
en-aut-mei=Hitoshi
kn-aut-name=高島均
kn-aut-sei=高島
kn-aut-mei=均
aut-affil-num=4
ORCID=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=5
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=6
ORCID=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=7
ORCID=
en-aut-name=OkaMichiko
en-aut-sei=Oka
en-aut-mei=Michiko
kn-aut-name=岡美智子
kn-aut-sei=岡
kn-aut-mei=美智子
aut-affil-num=8
ORCID=
en-aut-name=AndohAkio
en-aut-sei=Andoh
en-aut-mei=Akio
kn-aut-name=安藤陽夫
kn-aut-sei=安藤
kn-aut-mei=陽夫
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=8
en-affil=
kn-affil=大川総合病院内科
affil-num=9
en-affil=
kn-affil=大川総合病院外科
en-keyword=気腫性胆嚢炎
kn-keyword=気腫性胆嚢炎
en-keyword=急性胆嚢炎
kn-keyword=急性胆嚢炎
en-keyword=超音波診断
kn-keyword=超音波診断
en-keyword=CT
kn-keyword=CT
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=43
end-page=51
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Radiological diagnosis and treatment of afferent loop obstruction
kn-title=輸入脚閉塞症の画像診断と治療
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Four cases of afferent loop obtruction were reported. Billroth II reconstruction was performed in two patients and Roux-Y reconstruction was performed in the other two patients after gastrectomy. Three of four patients complained of jaundice. CT and ultrasonography showed a dumbell-shaped cystic mass anterior to the abdominal aorta on the transverse image, and a cystic mass between the superior mesenteric vessels and the abdominal aorta on saggital view. These patients were not surgical candidates because of their poor condition. We performed the drainage of the afferent loop via a percutaneus transhepatic biliary catheter as a palliative treatment. In one case the serum bilirubin and amylase level decreased to normal range and the patient survived for 80 days. The other two patients died on the 12th and 28th day after the procedure. One patient is currently alive 20 days after the drainage procedure with improvement of clinical symptoms, serum bilirubin and amylase levels.
en-copyright=
kn-copyright=
en-aut-name=MatsunoShinsuke
en-aut-sei=Matsuno
en-aut-mei=Shinsuke
kn-aut-name=松野慎介
kn-aut-sei=松野
kn-aut-mei=慎介
aut-affil-num=1
ORCID=
en-aut-name=KojimaKanji
en-aut-sei=Kojima
en-aut-mei=Kanji
kn-aut-name=児島完治
kn-aut-sei=児島
kn-aut-mei=完治
aut-affil-num=2
ORCID=
en-aut-name=MoriYasutane
en-aut-sei=Mori
en-aut-mei=Yasutane
kn-aut-name=森泰胤
kn-aut-sei=森
kn-aut-mei=泰胤
aut-affil-num=3
ORCID=
en-aut-name=KageyamaJunichi
en-aut-sei=Kageyama
en-aut-mei=Junichi
kn-aut-name=影山淳一
kn-aut-sei=影山
kn-aut-mei=淳一
aut-affil-num=4
ORCID=
en-aut-name=ToyamaYoshihiro
en-aut-sei=Toyama
en-aut-mei=Yoshihiro
kn-aut-name=外山芳弘
kn-aut-sei=外山
kn-aut-mei=芳弘
aut-affil-num=5
ORCID=
en-aut-name=TsuuchiYasuhiko
en-aut-sei=Tsuuchi
en-aut-mei=Yasuhiko
kn-aut-name=津内保彦
kn-aut-sei=津内
kn-aut-mei=保彦
aut-affil-num=6
ORCID=
en-aut-name=YodenMidori
en-aut-sei=Yoden
en-aut-mei=Midori
kn-aut-name=余田みどり
kn-aut-sei=余田
kn-aut-mei=みどり
aut-affil-num=7
ORCID=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=8
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=9
ORCID=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=10
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=9
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=10
en-affil=
kn-affil=香川医科大学放射線医学教室
en-keyword=超音波診断
kn-keyword=超音波診断
en-keyword=CT
kn-keyword=CT
en-keyword=輸入脚閉塞症
kn-keyword=輸入脚閉塞症
en-keyword=PTCD
kn-keyword=PTCD
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=37
end-page=41
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=CT evaluation of vascular invasion in pancreatic carcinoma
kn-title=CTによる膵癌の大血管浸潤の評価―血管造影所見・手術所見との対比―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A new method of factor analysis has been devised as a dynamic study in nuclear medicine. Instead of whole sequence factor analysis of images, partially-sequenced images of Kr-81m pulmonary ventilation scintigrams, acquired with respiratory-gated signals, were analysed using this method. Incrementing the first and last frame number of the image sequence, the motion of the factor images, was obtained including diaphragmatic images, thoracic images and physiological pathological dead space, during one respiratory cycle. The varying form of the correlation between two factor images over time provided a distinguishable pattern of patients with pathological conditions such as chronic obstructive pulmonary disese from normal subjects.
en-copyright=
kn-copyright=
en-aut-name=HosokawaNobuyuki
en-aut-sei=Hosokawa
en-aut-mei=Nobuyuki
kn-aut-name=細川敦之
kn-aut-sei=細川
kn-aut-mei=敦之
aut-affil-num=1
ORCID=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=2
ORCID=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=3
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=4
ORCID=
en-aut-name=KojimaKanji
en-aut-sei=Kojima
en-aut-mei=Kanji
kn-aut-name=児島完治
kn-aut-sei=児島
kn-aut-mei=完治
aut-affil-num=5
ORCID=
en-aut-name=KageyamaJunichi
en-aut-sei=Kageyama
en-aut-mei=Junichi
kn-aut-name=影山淳一
kn-aut-sei=影山
kn-aut-mei=淳一
aut-affil-num=6
ORCID=
en-aut-name=TsuuchiYasuhiko
en-aut-sei=Tsuuchi
en-aut-mei=Yasuhiko
kn-aut-name=津内保彦
kn-aut-sei=津内
kn-aut-mei=保彦
aut-affil-num=7
ORCID=
en-aut-name=ToyamaYoshihiro
en-aut-sei=Toyama
en-aut-mei=Yoshihiro
kn-aut-name=外山芳弘
kn-aut-sei=外山
kn-aut-mei=芳弘
aut-affil-num=8
ORCID=
en-aut-name=MoriYasutane
en-aut-sei=Mori
en-aut-mei=Yasutane
kn-aut-name=森泰胤
kn-aut-sei=森
kn-aut-mei=泰胤
aut-affil-num=9
ORCID=
en-aut-name=YodenMidori
en-aut-sei=Yoden
en-aut-mei=Midori
kn-aut-name=余田みどり
kn-aut-sei=余田
kn-aut-mei=みどり
aut-affil-num=10
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=9
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=10
en-affil=
kn-affil=香川医科大学放射線医学教室
en-keyword=膵癌
kn-keyword=膵癌
en-keyword=大血管浸潤
kn-keyword=大血管浸潤
en-keyword=CT所見
kn-keyword=CT所見
en-keyword=血管造影所見
kn-keyword=血管造影所見
en-keyword=手術所見
kn-keyword=手術所見
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=31
end-page=36
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Dynamic study of lung ventilation by partial sequence factor analysis
kn-title=Partial Sequence Factor Analysisによる肺機能解析
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A new method of factor analysis has been devised as a dynamic study in nuclear medicine. Instead of whole sequence factor analysis of images, partially-sequenced images of Kr-81m pulmonary ventilation scintigrams, acquired with respiratory-gated signals, were analysed using this method. Incrementing the first and last frame number of the image sequence, the motion of the factor images, was obtained including diaphragmatic images, thoracic images and physiological pathological dead space, during one respiratory cycle. The varying form of the correlation between two factor images over time provided a distinguishable pattern of patients with pathological conditions such as chronic obstructive pulmonary disese from normal subjects.
en-copyright=
kn-copyright=
en-aut-name=TachikawaAkira
en-aut-sei=Tachikawa
en-aut-mei=Akira
kn-aut-name=立川光
kn-aut-sei=立川
kn-aut-mei=光
aut-affil-num=1
ORCID=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=2
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
en-keyword=ファクター・アナリシス
kn-keyword=ファクター・アナリシス
en-keyword=(81m)Kr-ガス肺換気シンチ
kn-keyword=(81m)Kr-ガス肺換気シンチ
en-keyword=呼吸同調
kn-keyword=呼吸同調
en-keyword=因子画像
kn-keyword=因子画像
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=25
end-page=29
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Ga-67 study in a patient with hepatocellular carcinoma after transcatheter arterial embolization
kn-title=肝細胞癌に対するTranscatheter arterial embolization後の(67)Gaの有用性
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A Ga-67 study was performed in a 70 years old man who had hepatocellular carcinoma (HCC) treated with transcatheter arterial embolization (TAE). High Ga-67 accumulation previously noted in the HCC lesion was not seen after TAE. These findings may provide important clinical informations regarding success of TAE and regarding as a reference for follow up study.
en-copyright=
kn-copyright=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=1
ORCID=
en-aut-name=HinoIchiroh
en-aut-sei=Hino
en-aut-mei=Ichiroh
kn-aut-name=日野一郎
kn-aut-sei=日野
kn-aut-mei=一郎
aut-affil-num=2
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=3
ORCID=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=4
ORCID=
en-aut-name=SatohKatashi
en-aut-sei=Satoh
en-aut-mei=Katashi
kn-aut-name=佐藤功
kn-aut-sei=佐藤
kn-aut-mei=功
aut-affil-num=5
ORCID=
en-aut-name=MizukawaKiichiroh
en-aut-sei=Mizukawa
en-aut-mei=Kiichiroh
kn-aut-name=水川帰一郎
kn-aut-sei=水川
kn-aut-mei=帰一郎
aut-affil-num=6
ORCID=
en-aut-name=KawaseYoshiroh
en-aut-sei=Kawase
en-aut-mei=Yoshiroh
kn-aut-name=川瀬悦郎
kn-aut-sei=川瀬
kn-aut-mei=悦郎
aut-affil-num=7
ORCID=
en-aut-name=SeoHiroyuki
en-aut-sei=Seo
en-aut-mei=Hiroyuki
kn-aut-name=瀬尾裕之
kn-aut-sei=瀬尾
kn-aut-mei=裕之
aut-affil-num=8
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学医学部放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学医学部放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学医学部放射線医学教室
en-keyword=肝細胞癌
kn-keyword=肝細胞癌
en-keyword=TAE
kn-keyword=TAE
en-keyword=(67)Ga-citrate
kn-keyword=(67)Ga-citrate
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=17
end-page=23
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Radiological estimation of branching patterns of the pulmonary artery in the left lingula
kn-title=左上葉舌区の肺動脈分岐のX線学的検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The purpose of this study is to estimate the coronal and cross sectional appearance of the branching patterns of the pulmonary artery in the left lingula using pulmonary tomography and computed tomography (CT). Eight specimens were analyzed; five were interlobar type (arising from pars interbobaris) and three were mixed type. The mediastinal type (arising from pars mediastinalis) was not seen. In 75% (segmental), and 50% (subsegmental), the branching patterns were estimated radiologically. With radiological findings, the arteries of mediastinal type run to the upper or mediastinal side of the bronchus and the arteries of the interlober type run outside or out-lowerside of the bronchus. It is difficult to estimate the branching patterns of the pulmonary artery in the left lingula because of the oblique projection of the arteries.
en-copyright=
kn-copyright=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=1
ORCID=
en-aut-name=SeoHiroyuki
en-aut-sei=Seo
en-aut-mei=Hiroyuki
kn-aut-name=瀬尾裕之
kn-aut-sei=瀬尾
kn-aut-mei=裕之
aut-affil-num=2
ORCID=
en-aut-name=SatohKatashi
en-aut-sei=Satoh
en-aut-mei=Katashi
kn-aut-name=佐藤功
kn-aut-sei=佐藤
kn-aut-mei=功
aut-affil-num=3
ORCID=
en-aut-name=GoudaFuminori
en-aut-sei=Gouda
en-aut-mei=Fuminori
kn-aut-name=合田文則
kn-aut-sei=合田
kn-aut-mei=文則
aut-affil-num=4
ORCID=
en-aut-name=KawasakiYukiko
en-aut-sei=Kawasaki
en-aut-mei=Yukiko
kn-aut-name=川崎幸子
kn-aut-sei=川崎
kn-aut-mei=幸子
aut-affil-num=5
ORCID=
en-aut-name=MizukawaKiichiroh
en-aut-sei=Mizukawa
en-aut-mei=Kiichiroh
kn-aut-name=水川帰一郎
kn-aut-sei=水川
kn-aut-mei=帰一郎
aut-affil-num=6
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=7
ORCID=
en-aut-name=MaedaMasazumi
en-aut-sei=Maeda
en-aut-mei=Masazumi
kn-aut-name=前田昌純
kn-aut-sei=前田
kn-aut-mei=昌純
aut-affil-num=8
ORCID=
en-aut-name=NakamuraKenji
en-aut-sei=Nakamura
en-aut-mei=Kenji
kn-aut-name=中村憲二
kn-aut-sei=中村
kn-aut-mei=憲二
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学医学部放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学医学部放射線医学教室
affil-num=8
en-affil=
kn-affil=香川医科大学第二外科医学教室
affil-num=9
en-affil=
kn-affil=香川医科大学第二外科医学教室
en-keyword=左上葉舌区
kn-keyword=左上葉舌区
en-keyword=肺動脈
kn-keyword=肺動脈
en-keyword=胸部CT
kn-keyword=胸部CT
en-keyword=胸部断層写真
kn-keyword=胸部断層写真
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=13
end-page=16
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=The status of Ga-67 citrate scintigraphic examination in Kagawa medical school hospital
kn-title=当院における(67)Ga-citrateシンチグラフィーの施行状況と考察
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=In 98 cases, Ga-67 citrate scintigraphic examination was performed from November 1983 to March 1985 in Kagawa Medical School Hospital. A restrospective evaluation of these cases showed that 38 cases (38.8%) did not meet indication for a Ga-67 study according to HISADA'S criteria. Of these 38 cases a positive Ga-67 uptake was shown in only 5 cases. Although application of Ga-67 detection is limited, many patients appear to receive a Ga-67 study without indication. The expensive Ga-67 study should be performed only in indicative cases.
en-copyright=
kn-copyright=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=1
ORCID=
en-aut-name=MizukawaKiichiroh
en-aut-sei=Mizukawa
en-aut-mei=Kiichiroh
kn-aut-name=水川帰一郎
kn-aut-sei=水川
kn-aut-mei=帰一郎
aut-affil-num=2
ORCID=
en-aut-name=HinoIchiroh
en-aut-sei=Hino
en-aut-mei=Ichiroh
kn-aut-name=日野一郎
kn-aut-sei=日野
kn-aut-mei=一郎
aut-affil-num=3
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=4
ORCID=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=5
ORCID=
en-aut-name=SatohKatashi
en-aut-sei=Satoh
en-aut-mei=Katashi
kn-aut-name=佐藤功
kn-aut-sei=佐藤
kn-aut-mei=功
aut-affil-num=6
ORCID=
en-aut-name=SeoHiroyuki
en-aut-sei=Seo
en-aut-mei=Hiroyuki
kn-aut-name=瀬尾裕之
kn-aut-sei=瀬尾
kn-aut-mei=裕之
aut-affil-num=7
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学医学部放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学医学部放射線医学教室
en-keyword=(67)Ga-citrate scintigraphy
kn-keyword=(67)Ga-citrate scintigraphy
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=7
end-page=12
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=An evaluation of utility of residual liver function prediction using dynamic SPECT
kn-title=dynamic SPECTによる残存肝機能測定の有用性について
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A method for evaluating and predicting residual liver function was devised for dynamic single photon emission computed tomography (SPECT). The ratio of residual volume to total effective liver volume, K value and predictive index using dynamic SPECT were compared with respective values using dynamic planar scintigraphy. The coefficients of correlation were 0.86 (the ratio), 0.91 (K value) and 0.88 (predictive index). The predictive index, measured by dynamic SPECT, was as useful as by dynamic planar scintigraphy. In addition, the resecting line using SPECT was more accurate than using planar scintigraphy. Dynamic SPECT was more useful than dynamic planar scintigraphy.
en-copyright=
kn-copyright=
en-aut-name=TanabeMasatada
en-aut-sei=Tanabe
en-aut-mei=Masatada
kn-aut-name=田邉正忠
kn-aut-sei=田邉
kn-aut-mei=正忠
aut-affil-num=1
ORCID=
en-aut-name=TamaiToyosato
en-aut-sei=Tamai
en-aut-mei=Toyosato
kn-aut-name=玉井豊理
kn-aut-sei=玉井
kn-aut-mei=豊理
aut-affil-num=2
ORCID=
en-aut-name=HinoIchiroh
en-aut-sei=Hino
en-aut-mei=Ichiroh
kn-aut-name=日野一郎
kn-aut-sei=日野
kn-aut-mei=一郎
aut-affil-num=3
ORCID=
en-aut-name=SatohKatashi
en-aut-sei=Satoh
en-aut-mei=Katashi
kn-aut-name=佐藤功
kn-aut-sei=佐藤
kn-aut-mei=功
aut-affil-num=4
ORCID=
en-aut-name=KojimaKanji
en-aut-sei=Kojima
en-aut-mei=Kanji
kn-aut-name=児島完治
kn-aut-sei=児島
kn-aut-mei=完治
aut-affil-num=5
ORCID=
en-aut-name=OhkawaMotoomi
en-aut-sei=Ohkawa
en-aut-mei=Motoomi
kn-aut-name=大川元臣
kn-aut-sei=大川
kn-aut-mei=元臣
aut-affil-num=6
ORCID=
en-aut-name=MaebaTakashi
en-aut-sei=Maeba
en-aut-mei=Takashi
kn-aut-name=前場隆志
kn-aut-sei=前場
kn-aut-mei=隆志
aut-affil-num=7
ORCID=
en-aut-name=TanakaSatoshi
en-aut-sei=Tanaka
en-aut-mei=Satoshi
kn-aut-name=田中聰
kn-aut-sei=田中
kn-aut-mei=聰
aut-affil-num=8
ORCID=
affil-num=1
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=2
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=3
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=4
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=5
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=6
en-affil=
kn-affil=香川医科大学放射線医学教室
affil-num=7
en-affil=
kn-affil=香川医科大学第一外科学教室
affil-num=8
en-affil=
kn-affil=香川医科大学第一外科学教室
en-keyword=肝切除
kn-keyword=肝切除
en-keyword=SPECT
kn-keyword=SPECT
en-keyword=K値
kn-keyword=K値
en-keyword=肝シンチグラフィー
kn-keyword=肝シンチグラフィー
END
start-ver=1.4
cd-journal=joma
no-vol=101
cd-vols=
no-issue=1-2
article-no=
start-page=1
end-page=6
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1989
dt-pub=198902
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Radiosensitivity of an isolated human malignant fibrous histiocytoma cell line
kn-title=組織培養による人癌細胞(悪性線維性組織球腫)の放射線に対する感受性―その1―
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A human cell line (YU-137) isolated from a bone of malignant fibrous histiocytoma in bone was evaluated using immunofluorescent staining methods. Cell cycle fractions were studied by flow cytometry. The magnitude of G(2)+M fraction in a cell cycle of an exponentially growing population of YU-137 was higher than that observed in HeLa S3 cells. The doubling time of YU-137 cells was 3.2 days. The radiosensitivity of this cell line was compared with HeLa S3 and HMV-1 cells from dose response curves against X-irradiation. The parameters of radiosensitivity of YU-137 against X-irradiation were n=2.0, D(0)=1.05 Gy and D(0)=0.73 Gy. From these data, the radiosensitivity of YU-137 was discussed.
en-copyright=
kn-copyright=
en-aut-name=KawasakiShoji
en-aut-sei=Kawasaki
en-aut-mei=Shoji
kn-aut-name=川崎祥二
kn-aut-sei=川崎
kn-aut-mei=祥二
aut-affil-num=1
ORCID=
en-aut-name=MizutaAkifumi
en-aut-sei=Mizuta
en-aut-mei=Akifumi
kn-aut-name=水田昭文
kn-aut-sei=水田
kn-aut-mei=昭文
aut-affil-num=2
ORCID=
en-aut-name=KashitaniNaoko
en-aut-sei=Kashitani
en-aut-mei=Naoko
kn-aut-name=柏谷尚子
kn-aut-sei=柏谷
kn-aut-mei=尚子
aut-affil-num=3
ORCID=
en-aut-name=KurodaMasahiro
en-aut-sei=Kuroda
en-aut-mei=Masahiro
kn-aut-name=黒田昌宏
kn-aut-sei=黒田
kn-aut-mei=昌宏
aut-affil-num=4
ORCID=
en-aut-name=HirakiYoshio
en-aut-sei=Hiraki
en-aut-mei=Yoshio
kn-aut-name=平木祥夫
kn-aut-sei=平木
kn-aut-mei=祥夫
aut-affil-num=5
ORCID=
en-aut-name=AonoKaname
en-aut-sei=Aono
en-aut-mei=Kaname
kn-aut-name=青野要
kn-aut-sei=青野
kn-aut-mei=要
aut-affil-num=6
ORCID=
en-aut-name=SatoJiro
en-aut-sei=Sato
en-aut-mei=Jiro
kn-aut-name=佐藤二郎
kn-aut-sei=佐藤
kn-aut-mei=二郎
aut-affil-num=7
ORCID=
en-aut-name=OginoTetsuro
en-aut-sei=Ogino
en-aut-mei=Tetsuro
kn-aut-name=荻野哲朗
kn-aut-sei=荻野
kn-aut-mei=哲朗
aut-affil-num=8
ORCID=
en-aut-name=NakanishiTakashi
en-aut-sei=Nakanishi
en-aut-mei=Takashi
kn-aut-name=中西敬
kn-aut-sei=中西
kn-aut-mei=敬
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医療技術短期大学部
affil-num=2
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=3
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=4
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=5
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=6
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=7
en-affil=
kn-affil=岡山大学医学部癌源研究施設病理学部門
affil-num=8
en-affil=
kn-affil=香川医科大学病院病理部
affil-num=9
en-affil=
kn-affil=山口大学医学部放射線医学教室
en-keyword=Tissue culture
kn-keyword=Tissue culture
en-keyword=Malignant fibrous histeocytoma
kn-keyword=Malignant fibrous histeocytoma
en-keyword=Radiosensitivity
kn-keyword=Radiosensitivity
en-keyword=Flow cytometry
kn-keyword=Flow cytometry
END
start-ver=1.4
cd-journal=joma
no-vol=102
cd-vols=
no-issue=9-10
article-no=
start-page=1167
end-page=1173
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199010
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Electron beam therapy in carcinoma of the buccal mucosa
kn-title=頬粘膜癌に対する電子線治療法の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Electron beam therapy has often been used for radiation therapy of carcinomas of the buccal mucosa, though side effects including, stomatitis and dermatitis are known to exist. We experimented using the additional back scatter and transit with the phantom under a lead plate within the irradiation field, in order to better focus the dose on the target volume moreover, we fabricated a mouthpiece fitted with a lead plate shaped to the target volume, and with respect to the influence of the mouthpiece on stomatitis and dermatitis, obtained good clinical results.
en-copyright=
kn-copyright=
en-aut-name=NakagiriYoshitada
en-aut-sei=Nakagiri
en-aut-mei=Yoshitada
kn-aut-name=中桐義忠
kn-aut-sei=中桐
kn-aut-mei=義忠
aut-affil-num=1
ORCID=
en-aut-name=MiyakeHideaki
en-aut-sei=Miyake
en-aut-mei=Hideaki
kn-aut-name=三宅英昭
kn-aut-sei=三宅
kn-aut-mei=英昭
aut-affil-num=2
ORCID=
en-aut-name=SugitaKatsuhiko
en-aut-sei=Sugita
en-aut-mei=Katsuhiko
kn-aut-name=杉田勝彦
kn-aut-sei=杉田
kn-aut-mei=勝彦
aut-affil-num=3
ORCID=
en-aut-name=MikamiYasutaka
en-aut-sei=Mikami
en-aut-mei=Yasutaka
kn-aut-name=三上泰隆
kn-aut-sei=三上
kn-aut-mei=泰隆
aut-affil-num=4
ORCID=
en-aut-name=InamuraKeiji
en-aut-sei=Inamura
en-aut-mei=Keiji
kn-aut-name=稲村圭司
kn-aut-sei=稲村
kn-aut-mei=圭司
aut-affil-num=5
ORCID=
en-aut-name=MimuraSeiichi
en-aut-sei=Mimura
en-aut-mei=Seiichi
kn-aut-name=三村誠一
kn-aut-sei=三村
kn-aut-mei=誠一
aut-affil-num=6
ORCID=
en-aut-name=OhkawaYoshihiro
en-aut-sei=Ohkawa
en-aut-mei=Yoshihiro
kn-aut-name=大川義弘
kn-aut-sei=大川
kn-aut-mei=義弘
aut-affil-num=7
ORCID=
en-aut-name=TakedaYoshihiro
en-aut-sei=Takeda
en-aut-mei=Yoshihiro
kn-aut-name=竹田芳弘
kn-aut-sei=竹田
kn-aut-mei=芳弘
aut-affil-num=8
ORCID=
en-aut-name=HirakiYoshio
en-aut-sei=Hiraki
en-aut-mei=Yoshio
kn-aut-name=平木祥夫
kn-aut-sei=平木
kn-aut-mei=祥夫
aut-affil-num=9
ORCID=
en-aut-name=FujikiTomokazu
en-aut-sei=Fujiki
en-aut-mei=Tomokazu
kn-aut-name=藤木知一
kn-aut-sei=藤木
kn-aut-mei=知一
aut-affil-num=10
ORCID=
en-aut-name=KishiKanji
en-aut-sei=Kishi
en-aut-mei=Kanji
kn-aut-name=岸幹二
kn-aut-sei=岸
kn-aut-mei=幹二
aut-affil-num=11
ORCID=
en-aut-name=ChiharaNaoto
en-aut-sei=Chihara
en-aut-mei=Naoto
kn-aut-name=千原直人
kn-aut-sei=千原
kn-aut-mei=直人
aut-affil-num=12
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医療短期大学部診療放射線技術学科
affil-num=2
en-affil=
kn-affil=岡山大学医療短期大学部診療放射線技術学科
affil-num=3
en-affil=
kn-affil=岡山大学医療短期大学部診療放射線技術学科
affil-num=4
en-affil=
kn-affil=岡山大学医学部附属病院中央放射線部
affil-num=5
en-affil=
kn-affil=岡山大学医学部附属病院中央放射線部
affil-num=6
en-affil=
kn-affil=岡山大学医学部附属病院中央放射線部
affil-num=7
en-affil=
kn-affil=岡山大学医学部附属病院中央放射線部
affil-num=8
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=9
en-affil=
kn-affil=岡山大学医学部放射線医学教室
affil-num=10
en-affil=
kn-affil=岡山大学歯学部歯科放射線学講座
affil-num=11
en-affil=
kn-affil=岡山大学歯学部歯科放射線学講座
affil-num=12
en-affil=
kn-affil=岡山大学歯学部第二口腔外科学講座
en-keyword=頬部粘膜癌
kn-keyword=頬部粘膜癌
en-keyword=電子線治療
kn-keyword=電子線治療
en-keyword=後方散乱線
kn-keyword=後方散乱線
en-keyword=mouthpiece
kn-keyword=mouthpiece
END
start-ver=1.4
cd-journal=joma
no-vol=102
cd-vols=
no-issue=5-6
article-no=
start-page=779
end-page=788
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199006
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Study of mitochondrial activity (Rhodamine 123 uptake) on Ehrlich ascites tumor cells and its adriamycin resistant cells
kn-title=Ehrlich腹水癌細胞およびAdriamycin耐性細胞のRhodamine 123 uptakeを指標としたミトコンドリア活性
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The positively charged fluorescent dye Rhodamine 123 (Rho 123) accumulates in mitochondria. An adriamycin (ADR)-resistant cell line derived from Ehrlich ascites tumor cells (wild EATC) was established in our laboratory. Overall mitochondrial activity of wild EATC and ADR-resistant EATC was investigated by the staining method with Rho 123. The uptake of Rho 123 into living cells was analyzed by flow cytometry. The intracellular Rho 123 uptake of ADR-resistant EATC was lower than that of wild EATC. The intracellular Rho 123 uptake of wild EATC increased when cells were treated with cepharanthine (CP). The intracellular Rho 123 uptake of ADR-resistant EATC increased markedly by CP treatment. ADR-resistant EATC cosumed more endogenous oxygen than wild EATC. The energy level of ADR-resistant EATC was discussed.
en-copyright=
kn-copyright=
en-aut-name=OkazakiYoshio
en-aut-sei=Okazaki
en-aut-mei=Yoshio
kn-aut-name=岡崎良夫
kn-aut-sei=岡崎
kn-aut-mei=良夫
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室
en-keyword=アドリアマイシン (ADR)
kn-keyword=アドリアマイシン (ADR)
en-keyword=ADR耐性細胞
kn-keyword=ADR耐性細胞
en-keyword=ミトコンドリア
kn-keyword=ミトコンドリア
en-keyword=Rhodamine 123
kn-keyword=Rhodamine 123
en-keyword=ハイパーサーミア
kn-keyword=ハイパーサーミア
END
start-ver=1.4
cd-journal=joma
no-vol=102
cd-vols=
no-issue=5-6
article-no=
start-page=679
end-page=690
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1990
dt-pub=199006
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Studies on overcoming resistance in adriamycin-resistant Ehrlich ascites tumor cells by hyperthermia and cepharanthine
kn-title=Ehrlich腹水癌細胞におけるAdriamycin耐性とその克服に関する研究
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=Adriamycin (ADR)-resistant Ehrlich ascites tumor cells (EATC) were established by repeated exposure to ADR. Using these resistant cells, the modification of the killing effect of ADR by hyperthermia and cepharanthine (CEP) was evaluated. The killing effect of ADR depended on the intracellular uptake and retention of ADR. ADR-resistant EATC had an enhanced acquired capacity that increased the efflux of intracellular ADR. Therefore, the intracellular uptake and retention of ADR were decreased. CEP inhibited the efflux of intracellular ADR and increased the intracellular retention of ADR, thereby enhancing the killing effect of ADR. Hyperthermic treatment increased the influx of ADR, but the killing effect of ADR was not enhanced by hyperthermia alone because of the increased efflux of intracellular ADR. However, with the combination of hyperthermia and CEP, hyperthermia accelerated the influx of ADR, and CEP suppressed the efflux of intracellular ADR. Then the intracellular uptake and retention of ADR were further increased, and the killing effect of ADR was markedly enhanced. Thus the combined use of hyperthermia and CEP reduced the resistance to ADR. These findings suggest that ADR resistance in cancer cells can be overcome by the combination of ADR, hyperthermia and CEP.
en-copyright=
kn-copyright=
en-aut-name=InoueNobuhiro
en-aut-sei=Inoue
en-aut-mei=Nobuhiro
kn-aut-name=井上信浩
kn-aut-sei=井上
kn-aut-mei=信浩
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学医学部放射線医学教室
en-keyword=Adriamycin
kn-keyword=Adriamycin
en-keyword=Adriamycin耐性細胞
kn-keyword=Adriamycin耐性細胞
en-keyword=Cepharanthine
kn-keyword=Cepharanthine
en-keyword=Hyperthermia
kn-keyword=Hyperthermia
END
start-ver=1.4
cd-journal=joma
no-vol=122
cd-vols=
no-issue=3
article-no=
start-page=219
end-page=223
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20101201
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=Radiotherapy for choroidal hemangioma
kn-title=脈絡膜血管腫に対する放射線治療
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=PURPOSE: Circumscribed choroidal hemangioma is an uncommon, benign vascular tumor that typically appears in the posterior pole of the eye. Visual acuity loss typically results from its exudation, followed by serous retinal detachment. The purpose of the study was to evaluate the efficacy and the safety of external beam irradiation in treating circumscribed choroidal hemangioma. METHODS: We treated 4 eyes of 4 patients with circumscribed choroidal hemangioma with external beam irradiation at Okayama University Hospital from 2002 to 2009. A total absorbed dose of 20 Gy (beam energy, 4, 10 MV) was applied to each of the 4 patients. Each patient received a single 2-Gy daily fraction for five consecutive days in a week, for two consecutive weeks. RESULTS: In all cases, the retinal detachment showed complete resolution within 8 to 48 days after treatment. A decrease in tumor thickness was observed in all cases except one in which the follow-up period was rather short (3.7 months). The visual acuity improved in all 4 eyes. No eyes showed deterioration of visual acuity. During follow-up periods of 3.7 months to 58.5 months, there were no signs of radiation-induced cataract, retinopathy or optic neuropathy.
en-copyright=
kn-copyright=
en-aut-name=HaradaSosuke
en-aut-sei=Harada
en-aut-mei=Sosuke
kn-aut-name=原田聡介
kn-aut-sei=原田
kn-aut-mei=聡介
aut-affil-num=1
ORCID=
en-aut-name=TakemotoMitsuhiro
en-aut-sei=Takemoto
en-aut-mei=Mitsuhiro
kn-aut-name=武本充広
kn-aut-sei=武本
kn-aut-mei=充広
aut-affil-num=2
ORCID=
en-aut-name=YoshioKoutarou
en-aut-sei=Yoshio
en-aut-mei=Koutarou
kn-aut-name=吉尾浩太郎
kn-aut-sei=吉尾
kn-aut-mei=浩太郎
aut-affil-num=3
ORCID=
en-aut-name=KojimaKatsuhide
en-aut-sei=Kojima
en-aut-mei=Katsuhide
kn-aut-name=児島克英
kn-aut-sei=児島
kn-aut-mei=克英
aut-affil-num=4
ORCID=
en-aut-name=KatayamaNorihisa
en-aut-sei=Katayama
en-aut-mei=Norihisa
kn-aut-name=片山敬久
kn-aut-sei=片山
kn-aut-mei=敬久
aut-affil-num=5
ORCID=
en-aut-name=KatsuiKuniaki
en-aut-sei=Katsui
en-aut-mei=Kuniaki
kn-aut-name=勝井邦彰
kn-aut-sei=勝井
kn-aut-mei=邦彰
aut-affil-num=6
ORCID=
en-aut-name=KurodaMasahiro
en-aut-sei=Kuroda
en-aut-mei=Masahiro
kn-aut-name=黒田昌宏
kn-aut-sei=黒田
kn-aut-mei=昌宏
aut-affil-num=7
ORCID=
en-aut-name=MatsuoToshihiko
en-aut-sei=Matsuo
en-aut-mei=Toshihiko
kn-aut-name=松尾俊彦
kn-aut-sei=松尾
kn-aut-mei=俊彦
aut-affil-num=8
ORCID=
en-aut-name=KanazawaSusumu
en-aut-sei=Kanazawa
en-aut-mei=Susumu
kn-aut-name=金澤右
kn-aut-sei=金澤
kn-aut-mei=右
aut-affil-num=9
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学病院 放射線科
affil-num=2
en-affil=
kn-affil=岡山大学病院 放射線科
affil-num=3
en-affil=
kn-affil=岡山大学病院 放射線科
affil-num=4
en-affil=
kn-affil=岡山大学病院 放射線科
affil-num=5
en-affil=
kn-affil=岡山大学病院 放射線科
affil-num=6
en-affil=
kn-affil=岡山大学病院 放射線科
affil-num=7
en-affil=
kn-affil=岡山大学大学院保健学研究科 放射線技術科学分野
affil-num=8
en-affil=
kn-affil=岡山大学病院 眼科
affil-num=9
en-affil=
kn-affil=岡山大学病院 放射線科
en-keyword=放射線治療 (radiation therapy)
kn-keyword=放射線治療 (radiation therapy)
en-keyword=照射 (irradiation)
kn-keyword=照射 (irradiation)
en-keyword=脈絡膜 (choroid)
kn-keyword=脈絡膜 (choroid)
en-keyword=眼腫瘍 (ocular tumor)
kn-keyword=眼腫瘍 (ocular tumor)
en-keyword=血管腫 (hemangioma)
kn-keyword=血管腫 (hemangioma)
END
start-ver=1.4
cd-journal=joma
no-vol=12
cd-vols=
no-issue=
article-no=
start-page=30
end-page=33
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=1953
dt-pub=195309
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=PROTECTIVE EFFECT OF THERMAL BATHS AGAINST TOTAL BODY X-IRRADIATION CHANGES OF LIVER-CATALASE ACTIVITY IN MICE
kn-title=温泉浴の放射線障碍に及ぼす影響-肝カタラーゼ活性値に見られた変化
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=The author investigated the effect of a series of thermal baths of Misasa, (at 37°C for 10 minutes), upon the liver-catalase activity in X-irradiated mice. The thermal baths, following LD 50 dose of X-irradiation (450r) or following a successive X-irradiation of daily 50r for 6 - 25 days decreased the liver-catalase activity more marked than control without baths. On the other hand, thermal baths prior to X-irradiation prevented the fall of liver-catalase activity in the X-irradated mice.
en-copyright=
kn-copyright=
en-aut-name=OkadaToshio
en-aut-sei=Okada
en-aut-mei=Toshio
kn-aut-name=岡田俊郎
kn-aut-sei=岡田
kn-aut-mei=俊郎
aut-affil-num=1
ORCID=
affil-num=1
en-affil=
kn-affil=岡山大学温泉研究所
END
start-ver=1.4
cd-journal=joma
no-vol=122
cd-vols=
no-issue=2
article-no=
start-page=125
end-page=127
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2010
dt-pub=20100802
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=A case of linea alba hernia with impaction of the falciform ligament of liver
kn-title=白線ヘルニアの1例:本邦手術症例85例の検討
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=A 78-year-old woman visited our hospital after developing severe abdominal pain and upper abdominal swelling. An emergency operation was performed following a diagnosis of linea alba hernia with impaction of the falciform ligament of the liver as observed on CT findings. A defect of about 30 mm in diameter was observed in the linea alba, and preperitoneal adipose tissue and the falciform ligament of the liver prolapsed from the location of the defect and were impacted. We resolved the impaction of the falciform ligament of the liver by dissecting it, and we resected the preperitoneal adipose tissue. Simple closure was performed to correct the hernia orifice because the surrounding tissue was relatively rigid and the tension was mild. The patient's condition improved, and she was discharged on the 5th postoperative day.
en-copyright=
kn-copyright=
en-aut-name=MiyasoHideaki
en-aut-sei=Miyaso
en-aut-mei=Hideaki
kn-aut-name=宮宗秀明
kn-aut-sei=宮宗
kn-aut-mei=秀明
aut-affil-num=1
ORCID=
en-aut-name=NishieManabu
en-aut-sei=Nishie
en-aut-mei=Manabu
kn-aut-name=西江学
kn-aut-sei=西江
kn-aut-mei=学
aut-affil-num=2
ORCID=
en-aut-name=IwagakiHiromi
en-aut-sei=Iwagaki
en-aut-mei=Hiromi
kn-aut-name=岩垣博巳
kn-aut-sei=岩垣
kn-aut-mei=博巳
aut-affil-num=3
ORCID=
en-aut-name=IshiiHiroo
en-aut-sei=Ishii
en-aut-mei=Hiroo
kn-aut-name=石井裕朗
kn-aut-sei=石井
kn-aut-mei=裕朗
aut-affil-num=4
ORCID=
en-aut-name=FujitaIsao
en-aut-sei=Fujita
en-aut-mei=Isao
kn-aut-name=藤田勲生
kn-aut-sei=藤田
kn-aut-mei=勲生
aut-affil-num=5
ORCID=
en-aut-name=TomodaJun
en-aut-sei=Tomoda
en-aut-mei=Jun
kn-aut-name=友田純
kn-aut-sei=友田
kn-aut-mei=純
aut-affil-num=6
ORCID=
affil-num=1
en-affil=
kn-affil=国立病院機構福山医療センター 外科
affil-num=2
en-affil=
kn-affil=国立病院機構福山医療センター 外科
affil-num=3
en-affil=
kn-affil=国立病院機構福山医療センター 外科
affil-num=4
en-affil=
kn-affil=国立病院機構福山医療センター 放射線科
affil-num=5
en-affil=
kn-affil=国立病院機構福山医療センター 内科
affil-num=6
en-affil=
kn-affil=国立病院機構福山医療センター 内科
en-keyword=白線ヘルニア (linea alba hernia)
kn-keyword=白線ヘルニア (linea alba hernia)
en-keyword=ヘルニア嵌頓 (strangulation)
kn-keyword=ヘルニア嵌頓 (strangulation)
END
start-ver=1.4
cd-journal=joma
no-vol=1
cd-vols=
no-issue=
article-no=
start-page=191
end-page=196
dt-received=
dt-revised=
dt-accepted=
dt-pub-year=2002
dt-pub=200212
dt-online=
en-article=
kn-article=
en-subject=
kn-subject=
en-title=
kn-title=Detection of defects at BGA solder joints by using X-ray imaging
en-subtitle=
kn-subtitle=
en-abstract=
kn-abstract=
In the surface mount technology, a ball grid array (BGA) has been used in the production of PC boards. This paper deals with the detection of defects at BGA solder joints in PC boards by using X-ray imaging. Types of defects at BGA solder joints are solder bridge, missing connection, solder voids, open connection and misregistration of parts. The problems of image analysis for the detection of defects at BGA solder joints are the detection accuracy and image processing time according to the speed of the production line. To get the design data for the development of the inspection system used in the surface mount process, it is important to develop image analysis techniques based on X-ray image data. At the first step of our study, we attempt to detect the characteristics of the solder bridges based on the image analysis technique.
en-copyright= kn-copyright= en-aut-name=SumimotoTetsuhiro en-aut-sei=Sumimoto en-aut-mei=Tetsuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MondouMunehiro en-aut-sei=Mondou en-aut-mei=Munehiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=FurukawaNoboru en-aut-sei=Furukawa en-aut-mei=Noboru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=OkadaSaburo en-aut-sei=Okada en-aut-mei=Saburo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Eastem Hiroshima Prefecture Industrial Research Institute affil-num=6 en-affil= kn-affil=Eastern Hiroshima Prefecture Industrial Research Institute affil-num=7 en-affil= kn-affil=National Institute of Advanced Industrial Science and Technology en-keyword=X-ray imaging kn-keyword=X-ray imaging en-keyword=ball grid arrays kn-keyword=ball grid arrays en-keyword=inspection kn-keyword=inspection en-keyword=printed circuit manufacture kn-keyword=printed circuit manufacture en-keyword=quality control kn-keyword=quality control en-keyword=surface mount technology kn-keyword=surface mount technology END start-ver=1.4 cd-journal=joma no-vol=2 cd-vols= no-issue= article-no= start-page=1131 end-page=1136 dt-received= dt-revised= dt-accepted= dt-pub-year=2003 dt-pub=20035 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Development of image analysis for detection of defects of BGA by using X-ray images en-subtitle= kn-subtitle= en-abstract= kn-abstract=In the surface mount technology, Ball Grid Array (BGA) has been used in a production of PC boards, because of their excellent characters such as high density of the lead pin pitch, better lead rigidity and self-alignment during re-flow processing. This paper deals with the development of image analysis for the detection of defects at BGA solder joints in PC boards by using X-ray images. In the conventional IC boards, it is possible to detect defects of solder joints by visual inspection, because the lead of IC package is set on its outside. However, we can't detect visually defects at BGA solder joints, because they are hidden under the IC package. In a production line, the inspection of BGA in PC boards depends on the function test of electric circuits in the final process. To improve a cost performance and the reliability of PC boards, an inspection of BGA is required in the surface mount process. Types of defects at BGA solder joints are solder bridge, missing connection, solder voids, open connection and miss-registration of parts. As we can find mostly solder bridge in these defects, we pick up this to detect solder bridge in a production line. The problems of image analysis for the detection of defects at BGA solder joints are the detection accuracy and image processing time according to a line speed of production. To get design data for the development of the inspection system, which can be used easily in the surface mount process, it is important to develop image analysis techniques based on X-ray image data. At the first step of our study, we attempt to detect the characteristic of the solder bridges based on an image analysis.
en-copyright= kn-copyright= en-aut-name=SumimotoTetsuhiro en-aut-sei=Sumimoto en-aut-mei=Tetsuhiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=MondouMunehiro en-aut-sei=Mondou en-aut-mei=Munehiro kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= en-aut-name=FurukawaNoboru en-aut-sei=Furukawa en-aut-mei=Noboru kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=6 ORCID= en-aut-name=OkadaSaburo en-aut-sei=Okada en-aut-mei=Saburo kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Eastern Hiroshima Prefecture Industrial Research Institute affil-num=6 en-affil= kn-affil=Eastern Hiroshima Prefecture Industrial Research Institute affil-num=7 en-affil= kn-affil=National Institute of Advanced Industrial Science and Technology en-keyword=X-ray imaging kn-keyword=X-ray imaging en-keyword=ball grid arrays kn-keyword=ball grid arrays en-keyword=image processing kn-keyword=image processing en-keyword=inspection kn-keyword=inspection en-keyword=printed circuit manufacture kn-keyword=printed circuit manufacture en-keyword=quality control kn-keyword=quality control en-keyword=surface mount technology kn-keyword=surface mount technology END start-ver=1.4 cd-journal=joma no-vol=28 cd-vols= no-issue=5 article-no= start-page=299 end-page=310 dt-received= dt-revised= dt-accepted= dt-pub-year=1974 dt-pub=197410 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=Studies on ferrous ion-induced lipid peroxidation of rat liver mitochondria. I. Effect of inorganic phosphate en-subtitle= kn-subtitle= en-abstract= kn-abstract=Effect of inorganic phosphate on ferrous ion- and ascorbate-induced lipid. peroxidations of isolated rat liver mitochondria was investigated. As a result it has been shown that phosphate accelerates the ferrous ion.induced lipid peroxidation; namely, phos. phate shortens the induction lag period of the lipid peroxidation reaction but the malondialdehyde after onset of its production is yielded at the same rate in various concentrations of phosphate. On the other hand, phosphate inhibits ascorbate.induced lipid peroxidation. There are stoichiometric interactions between the concentration of phos. phate and the induction period. Oxygen uptake by mitochondria was observed in the presence of both ferrous ion and phosphate at initial step of the reaction without being accompanied by malondialdehyde production, and afterwards there occurred malondialdehyde production with rapid rate of the oxygen uptake. Possible mechanisms and interactions among ferrous ion, ascorbate and phosphate were discussed.
en-copyright= kn-copyright= en-aut-name=YamamotoGoki en-aut-sei=Yamamoto en-aut-mei=Goki kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=2 ORCID= en-aut-name=WakabayashiHiroshi en-aut-sei=Wakabayashi en-aut-mei=Hiroshi kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=3 ORCID= en-aut-name=HashimotoGonosuke en-aut-sei=Hashimoto en-aut-mei=Gonosuke kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=4 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=Okayama University affil-num=2 en-affil= kn-affil=Okayama University affil-num=3 en-affil= kn-affil=Okayama University affil-num=4 en-affil= kn-affil=Okayama University affil-num=5 en-affil= kn-affil=Okayama University END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=正常とアカタラセミアなマウスの間に全身照射による放射線感受性に差異はない kn-title=No Different Sensitivity in Terms of Whole-body Irradiation Between Normal and Acatalasemic Mice en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NakagawaShinya en-aut-sei=Nakagawa en-aut-mei=Shinya kn-aut-name=中川慎也 kn-aut-sei=中川 kn-aut-mei=慎也 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=α-Al(2)O(3) における放射線損傷の分光学的研究 kn-title=The Spectroscopic Study of Radiation Damages in α-Al(2)O(3) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=AbuZayed Mohammad Saliqur Rahman en-aut-sei=Abu en-aut-mei=Zayed Mohammad Saliqur Rahman kn-aut-name=アブジャイド サリクール ラハマン kn-aut-sei=アブ kn-aut-mei=ジャイド サリクール ラハマン aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol=51 cd-vols= no-issue= article-no= start-page=25 end-page=33 dt-received= dt-revised= dt-accepted= dt-pub-year=1981 dt-pub=19810325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Determination of environmental radiation at radioactive spa areas in the Sanin districts kn-title=山陰地方の温泉地における環境放射線量について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Dose rates of environmental radiation were determined with NaI (Tl) cristal scintillation survey meter at Misasa, Sekigane and Ikeda spa areas which were known as radioactive spring in the Sanin districts. The results were as follows ; (1) Dose rates of radiation in the air of outdoor at spa areas of Misasa, Sekigane and Ikeda were 11.8±2.3μR/h, 11.3±2.1μR/h and 18.4±5.8μR/h, respectively. Dose rates of radiation in the air of these spa areas were significantly higher (P<0.01) than at none spa area of Kurayoshi city (8.6±1.2μR/h). Dose rates of radiation in the outdoor air at Misasa and Sekigane tends to increase near the spring sources. (2) In the room where spring water is not used, dose rates of radiation in the air were 9.5〜10.5μR/h. Dose rates of radiation in the air of the room with facilities using spring water were determined; peloid therapy room: 13.3±0.5μR/h, Hubbard bath room : 12.5±0.4μR/h, drinking hall : 11.8±0.7μR/h, hot air bathing room : 18.2±1.7μR/h, usual bath room (Onkensen) : 13.0±1.0μR/h and bath room for patients : 17.9±1.2μR/h (males), 17.0±1.2μR/h (females), respectively. Dose rates of radiation in the air of the bath room of Gunze-hotel and Ohashi-hotel-Gankutsunoyu were 30.1±9.0μR/h and22.3±3.0μR/h, respectively. At Ikeda spa, dose rates of radiation in the air of the guest room and the bath room were range of 13.0〜19.0μR/h and 14.0〜23.0μR/h. en-copyright= kn-copyright= en-aut-name=FurunoKatsushi en-aut-sei=Furuno en-aut-mei=Katsushi kn-aut-name=古野勝志 kn-aut-sei=古野 kn-aut-mei=勝志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学温泉研究所温泉内科学部門 END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=12 end-page=16 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=199809 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=癌の遺伝子治療 en-subtitle= kn-subtitle= en-abstract= kn-abstract=癌抑制遺伝子p53の突然変異や欠損による機能的異常は、多くのヒト癌で普遍的かつ高頻度に認められている。p53タンパク質の機能の一つとしては、細胞増殖に関するいろいろな遺伝子の発現制御を介した細胞周期の調節が考えられているが、その他に最近アポトーシスの誘導分子としても注目を浴びてきている。正常型p53遺伝子を有する胃癌、大腸癌では、術前化学療法や放射線療法で癌細胞のアポトーシスが誘導されたが、変異型p53を発現する腫瘍 ではアポトーシスに陥った細胞はほとんど認められなかった。ヌードマウスの皮下に移植したp53遺伝子に異常を持つヒト肺癌腫瘍にリコンビナント・アデノウイルスベクターを用いて正常型p53遺伝子を導入すると、抗癌剤に対する感受性が劇的に増強し、シスプラチンの腹腔内投与により腫瘍内にアポトーシスによる広範囲な組織破壊が認められた。この正常型p53発現アデノウイルスベクターとDNA障害性抗癌剤を併用した遺伝子治療は、臨床的にヒト悪性腫癌に応用可能と考えられる。 en-copyright= kn-copyright= en-aut-name=TanakaNoriaki en-aut-sei=Tanaka en-aut-mei=Noriaki kn-aut-name=田中紀章 kn-aut-sei=田中 kn-aut-mei=紀章 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一外科 END start-ver=1.4 cd-journal=joma no-vol=15 cd-vols= no-issue= article-no= start-page=13 end-page=22 dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19931215 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Monitoring of Environmental Ionizing Radiation and Radioisotopes in Okayama City and the Vicinty (I) kn-title=岡山市周辺の環境放射線ならびに放射能の調査・研究(I) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TadaMikiro en-aut-sei=Tada en-aut-mei=Mikiro kn-aut-name=多田幹郎 kn-aut-sei=多田 kn-aut-mei=幹郎 aut-affil-num=1 ORCID= en-aut-name=OnoBun-ichiro en-aut-sei=Ono en-aut-mei=Bun-ichiro kn-aut-name=小野文一郎 kn-aut-sei=小野 kn-aut-mei=文一郎 aut-affil-num=2 ORCID= en-aut-name=KanayamaMunetoshi en-aut-sei=Kanayama en-aut-mei=Munetoshi kn-aut-name=鑛山宗利 kn-aut-sei=鑛山 kn-aut-mei=宗利 aut-affil-num=3 ORCID= en-aut-name=HachiyaKinji en-aut-sei=Hachiya en-aut-mei=Kinji kn-aut-name=蜂谷欽司 kn-aut-sei=蜂谷 kn-aut-mei=欽司 aut-affil-num=4 ORCID= en-aut-name=SatohKimiyuki en-aut-sei=Satoh en-aut-mei=Kimiyuki kn-aut-name=佐藤公行 kn-aut-sei=佐藤 kn-aut-mei=公行 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学農学部 affil-num=2 en-affil= kn-affil=岡山大学薬学部 affil-num=3 en-affil= kn-affil=岡山大学RI共同利用津島施設 affil-num=4 en-affil= kn-affil=岡山大学RI共同利用津島施設 affil-num=5 en-affil= kn-affil=岡山大学理学部 END start-ver=1.4 cd-journal=joma no-vol=16 cd-vols= no-issue= article-no= start-page=3 end-page=10 dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19941225 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Monitoring of Environmental Ionizing Radiation and Radioisotopes in Okayama City and the Vicinty (II) - An estimation of the external radiation from the environmental radiation dose - kn-title=岡山市周辺の環境放射線ならびに放射能の調査・研究(II)―環境レベルの空間線量からの外部被曝に関する評価― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Monitoring of environmental ionizing radiation and radioisotopes in Okayama city and the vicinity was carried out from the point of view of the external radiation from the environmental radiation dose. Although the fluctuation of monthly detected radiation dose throughout the year was rather low at each observation point, the mean value of dose equivalent was varied between the place of observation. From the observation of the distribution of environmental radiation dose in Okayama city, it was assumed that its distribution was well corresponded with the distribution of igneous rocks. The concentrations of radioisotopes in various kinds of rocks corrected in Okayama city and its vicinity were determined. It became apparent that high concentrations of radioisotopes, such as (134)Cs, (40)K, (226)Ra and (228)Th, were detected in igneous rocks, such as granite, gabbro and rhyolitic tuff, although the contents in sedimentary rocks, such as pelite, schist, psammite and limestone, were rather low. This result was in good agreement with that of the distribution of radiation dose in Okayama city. en-copyright= kn-copyright= en-aut-name=MioMitsunobu en-aut-sei=Mio en-aut-mei=Mitsunobu kn-aut-name=見尾光庸 kn-aut-sei=見尾 kn-aut-mei=光庸 aut-affil-num=1 ORCID= en-aut-name=KanayamaMunetoshi en-aut-sei=Kanayama en-aut-mei=Munetoshi kn-aut-name=鑛山宗利 kn-aut-sei=鑛山 kn-aut-mei=宗利 aut-affil-num=2 ORCID= en-aut-name=TadaMikiro en-aut-sei=Tada en-aut-mei=Mikiro kn-aut-name=多田幹郎 kn-aut-sei=多田 kn-aut-mei=幹郎 aut-affil-num=3 ORCID= en-aut-name=OnoBun-ichiro en-aut-sei=Ono en-aut-mei=Bun-ichiro kn-aut-name=小野文一郎 kn-aut-sei=小野 kn-aut-mei=文一郎 aut-affil-num=4 ORCID= en-aut-name=HachiyaKinji en-aut-sei=Hachiya en-aut-mei=Kinji kn-aut-name=蜂谷欽司 kn-aut-sei=蜂谷 kn-aut-mei=欽司 aut-affil-num=5 ORCID= en-aut-name=SatohKimiyuki en-aut-sei=Satoh en-aut-mei=Kimiyuki kn-aut-name=佐藤公行 kn-aut-sei=佐藤 kn-aut-mei=公行 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学薬学部 affil-num=2 en-affil= kn-affil=岡山大学RI共同利用津島施設 affil-num=3 en-affil= kn-affil=岡山大学農学部 affil-num=4 en-affil= kn-affil=岡山大学薬学部 affil-num=5 en-affil= kn-affil=岡山大学RI共同利用津島施設 affil-num=6 en-affil= kn-affil=岡山大学理学部 END start-ver=1.4 cd-journal=joma no-vol=17 cd-vols= no-issue= article-no= start-page=63 end-page=70 dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19951220 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relationship between X-ray Exposure and Patient Dose on the Radiological Diagnosis kn-title=診療用X線検査における撮影条件と被曝線量の関係について―特に腹部検査を対象して― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Patient dose is important consideration in the radiological examination and our environment regarding radiation. Many studies have been published about patient dose, but those data were classified by each organ or tissue. Actuarially, patient dose should be checked by each examined part of patient and each exposure equipment. In this paper, we measured absorbed dose at the depth of 0-200mm with the Mix-DP phantom. The phantom is made by tissue equivalent meterial and is designed to similitude abdominal part. Percentage Depth Dose (PDD) was calculated from these doses. Three single-phase generators and three three-phases generators were used in this measurement. These measurements were analyzed by each equipment, and consequently the clear difference of PDD between the exposure equipments was not found. As the result, we can estimate patient dose at a random depth by using PDD. Furthermore, we can easily know patient dose from the tube-voltage and current time product by the calculation including PDD.These data are very useful to manager patient dose on radiological diagnosis. en-copyright= kn-copyright= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=1 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=2 ORCID= en-aut-name=SibuyaKoichi en-aut-sei=Sibuya en-aut-mei=Koichi kn-aut-name=渋谷光一 kn-aut-sei=渋谷 kn-aut-mei=光一 aut-affil-num=3 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=4 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=5 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=6 ORCID= en-aut-name=SonoyamaMasayo en-aut-sei=Sonoyama en-aut-mei=Masayo kn-aut-name=園山真世 kn-aut-sei=園山 kn-aut-mei=真世 aut-affil-num=7 ORCID= en-aut-name=MoriokaYasuki en-aut-sei=Morioka en-aut-mei=Yasuki kn-aut-name=森岡泰樹 kn-aut-sei=森岡 kn-aut-mei=泰樹 aut-affil-num=8 ORCID= en-aut-name=InamuraKeiji en-aut-sei=Inamura en-aut-mei=Keiji kn-aut-name=稲村圭司 kn-aut-sei=稲村 kn-aut-mei=圭司 aut-affil-num=9 ORCID= en-aut-name=TaharaSeiji en-aut-sei=Tahara en-aut-mei=Seiji kn-aut-name=田原誠司 kn-aut-sei=田原 kn-aut-mei=誠司 aut-affil-num=10 ORCID= en-aut-name=UnoHirofumi en-aut-sei=Uno en-aut-mei=Hirofumi kn-aut-name=宇野弘文 kn-aut-sei=宇野 kn-aut-mei=弘文 aut-affil-num=11 ORCID= en-aut-name=KadohisaShigefumi en-aut-sei=Kadohisa en-aut-mei=Shigefumi kn-aut-name=門久繁文 kn-aut-sei=門久 kn-aut-mei=繁文 aut-affil-num=12 ORCID= en-aut-name=InoueTatsuya en-aut-sei=Inoue en-aut-mei=Tatsuya kn-aut-name=井上龍也 kn-aut-sei=井上 kn-aut-mei=龍也 aut-affil-num=13 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=2 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=4 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=5 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=7 en-affil= kn-affil= affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=9 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=10 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=11 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=12 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=13 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=14 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 en-keyword=医用放射線被曝 (patient dose) kn-keyword=医用放射線被曝 (patient dose) en-keyword=X線撮影条件 (X-ray exposure) kn-keyword=X線撮影条件 (X-ray exposure) en-keyword=線量測定 (Radiation dosimetry) kn-keyword=線量測定 (Radiation dosimetry) END start-ver=1.4 cd-journal=joma no-vol=20 cd-vols= no-issue= article-no= start-page=17 end-page=21 dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=199808 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Patient Dose on the Radiological Diagnosis of Abdomen - The Situation of Patient nose at Hospitals in Okayama Prefecture - kn-title=腹部単純X線撮影時の被曝線量―岡山県下の病院の現況― en-subtitle= kn-subtitle= en-abstract= kn-abstract=In 1995, we have published a paper about the basic data on the relation between X-ray exposure equipment and patient dose in Vol. 17 of the Journal "Environment Research and Control". In this time, we questioned hospitals in Okayama Prefecture about exposure equipments of abdomen. And we compared each hospital's exposure equipments with the basic data, calculated each patient dose, then we studied that differences. Various imaging system, for example; screen/film or imaging plate has been used at each hospitals, so that exposure are various and patient doses are very different. The exposure equipment decide that the X-ray photograph is good or bad, so we cannot treat it easily. But we think that we have to try to take X-ray photographs which are suit the purpose of diagnosis which as a small patient dose as possible. en-copyright= kn-copyright= en-aut-name=NakagiriYoshitada en-aut-sei=Nakagiri en-aut-mei=Yoshitada kn-aut-name=中桐義忠 kn-aut-sei=中桐 kn-aut-mei=義忠 aut-affil-num=1 ORCID= en-aut-name=AzumaYoshiharu en-aut-sei=Azuma en-aut-mei=Yoshiharu kn-aut-name=東義晴 kn-aut-sei=東 kn-aut-mei=義晴 aut-affil-num=2 ORCID= en-aut-name=MaruyamaToshinori en-aut-sei=Maruyama en-aut-mei=Toshinori kn-aut-name=丸山敏則 kn-aut-sei=丸山 kn-aut-mei=敏則 aut-affil-num=3 ORCID= en-aut-name=SibuyaKoichi en-aut-sei=Sibuya en-aut-mei=Koichi kn-aut-name=渋谷光一 kn-aut-sei=渋谷 kn-aut-mei=光一 aut-affil-num=4 ORCID= en-aut-name=GotoSachiko en-aut-sei=Goto en-aut-mei=Sachiko kn-aut-name=後藤佐知子 kn-aut-sei=後藤 kn-aut-mei=佐知子 aut-affil-num=5 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=6 ORCID= en-aut-name=MoriokaYasuki en-aut-sei=Morioka en-aut-mei=Yasuki kn-aut-name=森岡泰樹 kn-aut-sei=森岡 kn-aut-mei=泰樹 aut-affil-num=7 ORCID= en-aut-name=KadohisaSigefumi en-aut-sei=Kadohisa en-aut-mei=Sigefumi kn-aut-name=門久繁文 kn-aut-sei=門久 kn-aut-mei=繁文 aut-affil-num=8 ORCID= en-aut-name=InoueTatsuya en-aut-sei=Inoue en-aut-mei=Tatsuya kn-aut-name=井上龍也 kn-aut-sei=井上 kn-aut-mei=龍也 aut-affil-num=9 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=2 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=3 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=4 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=5 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=6 en-affil= kn-affil=岡山大学医療技術短期大学部診療放射線技術学科 affil-num=7 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=8 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=9 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=10 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 en-keyword=医用放射線被曝 kn-keyword=医用放射線被曝 en-keyword=X線撮影条件 kn-keyword=X線撮影条件 en-keyword=線量測定 kn-keyword=線量測定 END start-ver=1.4 cd-journal=joma no-vol=122 cd-vols= no-issue=1 article-no= start-page=55 end-page=59 dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100401 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Interventional radiology for vascular anomalies kn-title=血管腫・血管奇形に対するinterventional radiology en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MimuraHidefumi en-aut-sei=Mimura en-aut-mei=Hidefumi kn-aut-name=三村秀文 kn-aut-sei=三村 kn-aut-mei=秀文 aut-affil-num=1 ORCID= en-aut-name=FujiwaraHiroyasu en-aut-sei=Fujiwara en-aut-mei=Hiroyasu kn-aut-name=藤原寛康 kn-aut-sei=藤原 kn-aut-mei=寛康 aut-affil-num=2 ORCID= en-aut-name=HirakiTakao en-aut-sei=Hiraki en-aut-mei=Takao kn-aut-name=平木隆夫 kn-aut-sei=平木 kn-aut-mei=隆夫 aut-affil-num=3 ORCID= en-aut-name=GobaraHideo en-aut-sei=Gobara en-aut-mei=Hideo kn-aut-name=郷原英夫 kn-aut-sei=郷原 kn-aut-mei=英夫 aut-affil-num=4 ORCID= en-aut-name=ShibamotoKentaro en-aut-sei=Shibamoto en-aut-mei=Kentaro kn-aut-name=芝本健太郎 kn-aut-sei=芝本 kn-aut-mei=健太郎 aut-affil-num=5 ORCID= en-aut-name=KimataYoshihiro en-aut-sei=Kimata en-aut-mei=Yoshihiro kn-aut-name=木股敬裕 kn-aut-sei=木股 kn-aut-mei=敬裕 aut-affil-num=6 ORCID= en-aut-name=OzakiToshifumi en-aut-sei=Ozaki en-aut-mei=Toshifumi kn-aut-name=尾ア敏文 kn-aut-sei=尾ア kn-aut-mei=敏文 aut-affil-num=7 ORCID= en-aut-name=SasakiSatoru en-aut-sei=Sasaki en-aut-mei=Satoru kn-aut-name=佐々木了 kn-aut-sei=佐々木 kn-aut-mei=了 aut-affil-num=8 ORCID= en-aut-name=KanazawaSusumu en-aut-sei=Kanazawa en-aut-mei=Susumu kn-aut-name=金澤右 kn-aut-sei=金澤 kn-aut-mei=右 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学 affil-num=3 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学 affil-num=4 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学 affil-num=5 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学 affil-num=6 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 形成再建外科学 affil-num=7 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 整形外科学 affil-num=8 en-affil= kn-affil=斗南病院形成外科 affil-num=9 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 放射線医学 en-keyword=血管奇形 kn-keyword=血管奇形 en-keyword=静脈奇形 kn-keyword=静脈奇形 en-keyword=動静脈奇形 kn-keyword=動静脈奇形 en-keyword=塞栓術 kn-keyword=塞栓術 en-keyword=硬化療法 kn-keyword=硬化療法 END start-ver=1.4 cd-journal=joma no-vol=60 cd-vols= no-issue= article-no= start-page=100 end-page=102 dt-received= dt-revised= dt-accepted= dt-pub-year=1989 dt-pub=198907 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Analytic study on colon examination for the past three years. kn-title=当院における大腸検査の検討 ―過去3年間のデータの分析― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=AkiyamaTsuneo en-aut-sei=Akiyama en-aut-mei=Tsuneo kn-aut-name=穐山恒雄 kn-aut-sei=穐山 kn-aut-mei=恒雄 aut-affil-num=1 ORCID= en-aut-name=NakaiMutsuo en-aut-sei=Nakai en-aut-mei=Mutsuo kn-aut-name=中井睦郎 kn-aut-sei=中井 kn-aut-mei=睦郎 aut-affil-num=2 ORCID= en-aut-name=OchiKoji en-aut-sei=Ochi en-aut-mei=Koji kn-aut-name=越智浩二 kn-aut-sei=越智 kn-aut-mei=浩二 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属三朝分院放射線室 affil-num=2 en-affil= kn-affil=岡山大学医学部附属三朝分院放射線室 affil-num=3 en-affil= kn-affil=岡山大学医学部環境病態研究施設 END start-ver=1.4 cd-journal=joma no-vol=68 cd-vols= no-issue=10 article-no= start-page=1645 end-page=1650 dt-received= dt-revised= dt-accepted= dt-pub-year=1956 dt-pub=19561031 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=INFLUENCE OF X-RAY IRRADIATION ON THE ACTION OFGLYCEROPHOSPHATASE AND ARGINASE OF THE UTERINE CANCER TISSUE kn-title=癌組織GlycerophosphataseおよびArginase作用におよぼすレ線の影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Experimental studies in vitro of the influence of X-ray irradiation on decomposing action of the glycerol extract of alkaline glycerophosphatase and arginase derived from the tissues of cervical cancer of the uterus and the musclature of the healthy uterine fundus have been attempted and the results obtained were reported as follows : 1. It has been shown that the cancerous tissue of cervic uteri contained more phosphoric acid and urea than the musclature of the normal fundus uteri. 2. It was found that the action of alkaline phosphatase and arginase of the uterine cancer tissue demonstrated stronger action than those of the tissue of fundus uteri. 3. Decomposing action of alkaline glycerophosphatase and arginase of the cancerous tissue of cervix uteri and the musclature of fundus could be suppressed when the enzymic extracts were irradiated and its effect was most pronounced with 300 r irradiation dosage. 4. Suppressing action of the alkaline glycerophosphatase when irradiated with X ray on the enzymic extracts of uterine carcinomatous tissue and fundus musclature, the malignant tissue would be more effective than the normal muscle tissue, while, the suppressing effect of the arginase, irradiated effect on enzymic extracts showed variation according to the dosage, but with 300 r, the effect was far more on the enzymic extract of the cancerous tissue. en-copyright= kn-copyright= en-aut-name=KandaM. en-aut-sei=Kanda en-aut-mei=M. kn-aut-name=神田瑞穂 kn-aut-sei=神田 kn-aut-mei=瑞穂 aut-affil-num=1 ORCID= en-aut-name=NakanishiY. en-aut-sei=Nakanishi en-aut-mei=Y. kn-aut-name=中西喜雄 kn-aut-sei=中西 kn-aut-mei=喜雄 aut-affil-num=2 ORCID= en-aut-name=MimuraK. en-aut-sei=Mimura en-aut-mei=K. kn-aut-name=三村公正 kn-aut-sei=三村 kn-aut-mei=公正 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=三木久也 kn-aut-sei=三木 kn-aut-mei=久也 aut-affil-num=4 ORCID= en-aut-name=YamamotoM. en-aut-sei=Yamamoto en-aut-mei=M. kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部法医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=59 cd-vols= no-issue= article-no= start-page=97 end-page=101 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=198808 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Application of personal computer in X-ray room business. kn-title=放射線業務におけるパソコン活用 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NakaiMutsuo en-aut-sei=Nakai en-aut-mei=Mutsuo kn-aut-name=中井睦郎 kn-aut-sei=中井 kn-aut-mei=睦郎 aut-affil-num=1 ORCID= en-aut-name=AkiyamaTsuneo en-aut-sei=Akiyama en-aut-mei=Tsuneo kn-aut-name=穐山恒雄 kn-aut-sei=穐山 kn-aut-mei=恒雄 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院放射線室 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院放射線室 END start-ver=1.4 cd-journal=joma no-vol=59 cd-vols= no-issue= article-no= start-page=93 end-page=96 dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=198808 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Changes in X-ray examinations. kn-title=放射線室における患者,検査の推移について ―患者数・件数・撮影枚数― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=AkiyamaTsuneo en-aut-sei=Akiyama en-aut-mei=Tsuneo kn-aut-name=穐山恒雄 kn-aut-sei=穐山 kn-aut-mei=恒雄 aut-affil-num=1 ORCID= en-aut-name=NakaiMutsuo en-aut-sei=Nakai en-aut-mei=Mutsuo kn-aut-name=中井睦郎 kn-aut-sei=中井 kn-aut-mei=睦郎 aut-affil-num=2 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院放射線室 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院放射線室 END start-ver=1.4 cd-journal=joma no-vol=57 cd-vols= no-issue= article-no= start-page=61 end-page=66 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=198607 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Angiography system combined with Toshiba BV-type X-TV Equipment. 2. Stereo-magnification system. kn-title=東芝BV型XTV装置を併用したANGIO graphy systemの使用経験(第2報 立体拡大撮影システム) en-subtitle= kn-subtitle= en-abstract=Angiography of the head and abdominal region gives a good deal of peculiar information for the diagnosis of nature of pathological lesions. When angiography could be performed by stereo-magnification radiography, the radiography gives better information for physicians. In this article, we tried angiography by the stereomagnifying radiography system utilizing X-TV equipment for examination of digestive system. 1. To magnify film image, the film changer was modified to move up and down, because the board of TV table did not change vertically. The board of TV table was also modified to slide more widely. The modifications could make it possible to magnify the film image by two times. 2. To use the X-TV equipment brought some advantages as follows it became very easy for us to convert the X-TV system from fluoroscopy to radiography, and contact seriography was easily changed to stereo-magnification seriography. kn-abstract=我々は,既設の消化管診断用X線TV装置(東芝BV型)を使用した立体拡大撮影システムを検討した。1.消化管診断用X線TV装置の透視天板の高さが一定であるため,従来のフィルムチェンジャー(AOT)では不可能であったが,上下動可能なフィルムチェンジャー(福放FC-10L特)を改良試作したことで最大2倍までの立体拡大撮影が可能となった。2.透視観察から撮影へ,コンタクト撮影から拡大連続撮影,立体撮影から立体拡大連続撮影へと併用して行うことが非常に簡単にできて被検者の負担軽減と多目的使用が可能となった。3.観察条件と立体感については,拡大率を変化させて,その立体感について検討した結果は、観察距離については,各拡大率における立体視しやすい距離は存在し,拡大率が2倍の場合には,観察距離を大きくするほど立体感も増加し,立体視し易い傾向が示された。 en-copyright= kn-copyright= en-aut-name=AkiyamaTsuneo en-aut-sei=Akiyama en-aut-mei=Tsuneo kn-aut-name=穐山恒雄 kn-aut-sei=穐山 kn-aut-mei=恒雄 aut-affil-num=1 ORCID= en-aut-name=NakaiMutsuo en-aut-sei=Nakai en-aut-mei=Mutsuo kn-aut-name=中井睦郎 kn-aut-sei=中井 kn-aut-mei=睦郎 aut-affil-num=2 ORCID= en-aut-name=MatsushimaKishio en-aut-sei=Matsushima en-aut-mei=Kishio kn-aut-name=松島紀志夫 kn-aut-sei=松島 kn-aut-mei=紀志夫 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院放射線室 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院放射線室 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院放射線部 en-keyword=立体拡大撮影 (Stereo-magnification radiography) kn-keyword=立体拡大撮影 (Stereo-magnification radiography) en-keyword=フィルム連続撮影装置 (Fiim changer) kn-keyword=フィルム連続撮影装置 (Fiim changer) en-keyword=立体感 (Stereoscopic image) kn-keyword=立体感 (Stereoscopic image) END start-ver=1.4 cd-journal=joma no-vol=57 cd-vols= no-issue= article-no= start-page=56 end-page=60 dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=198607 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Angiography system combined with Toshiba BV type X-TV equipment. 1. Whole limb serial aort-arteriography kn-title=東芝BV型XTV装置を併用したANGIO graphy systemの使用経験(第1報 下肢連続撮影装置) en-subtitle= kn-subtitle= en-abstract=A whole-limb serial aort-arteriography system constituted of BV-type X-TV and extralarge film changer was developed and used clinically. The results were as foll-ows. 1. By improving functions of the board of TV table, changes from fluoroscopy to radiography became easier in whole limb serial aort-arteriography. 2. By using LS-U screen and 1.0cm edge filter, we could get well compensated X-ray photographs. kn-abstract=消化管診断用X線TV装置の天板機能を改良し,種々のフィルムチェンジャー,X線管球を組み合わせることにより,中規模病院において,スペース,経費などの点で有利な,血管造影システムを組むことができた。第1報では,このうち,下肢連続撮影システムについて紹介する。1.透視から造影まで,迅速に移行できるシステムとなった。2.スペース,経費の点で有利である。3.濃度補償については,LS-U増感紙と,1.0cmエッジフィルターにより,体型によらず,全下肢にわたり,十分な補償効果が得られる。4.さらに長い長尺カセッテの開発が望まれる。 en-copyright= kn-copyright= en-aut-name=NakaiMutsuo en-aut-sei=Nakai en-aut-mei=Mutsuo kn-aut-name=中井睦郎 kn-aut-sei=中井 kn-aut-mei=睦郎 aut-affil-num=1 ORCID= en-aut-name=AkiyamaTsuneo en-aut-sei=Akiyama en-aut-mei=Tsuneo kn-aut-name=穐山恒雄 kn-aut-sei=穐山 kn-aut-mei=恒雄 aut-affil-num=2 ORCID= en-aut-name=MatsushimaKishio en-aut-sei=Matsushima en-aut-mei=Kishio kn-aut-name=松島紀志夫 kn-aut-sei=松島 kn-aut-mei=紀志夫 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院三朝分院放射線室 affil-num=2 en-affil= kn-affil=岡山大学医学部附属病院三朝分院放射線室 affil-num=3 en-affil= kn-affil=岡山大学医学部附属病院放射線部 en-keyword=全下肢連続動脈造影 (whole-limb serial aort-arteriography) kn-keyword=全下肢連続動脈造影 (whole-limb serial aort-arteriography) en-keyword=長尺フィルムチェンジャー (extra-large-film changer) kn-keyword=長尺フィルムチェンジャー (extra-large-film changer) en-keyword=X-TV台天板 (the board of TV table) kn-keyword=X-TV台天板 (the board of TV table) en-keyword=濃度補償 (compensation of density) kn-keyword=濃度補償 (compensation of density) END start-ver=1.4 cd-journal=joma no-vol=71 cd-vols= no-issue=5-1 article-no= start-page=2393 end-page=2398 dt-received= dt-revised= dt-accepted= dt-pub-year=1959 dt-pub=19590415 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Studies on the Nature of Radiation Disturbances Part 1. Influence of X-ray Irradiation on the Histochemical Changes in Blood Cells kn-title=放射線障碍の本態に関する実験的研究 第1編 放射線照射の血球に及ぼす組織化学的変化に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=There are many studies on radiation disturbances but as for the causative factor of the disturbances it is vaguely considered to be the disorders of the hematopoietic organs and still it is uncertain whether such disturbances are due to the primary or the secondary factor, However, in our experiments we have come across the evidence indicating that such disorders can be induced even by an indirect causative factor. Following upon this point, we have studied the problem from histochemical standpoint of blood cells and have clarified that various substances what may be called toxic granules are produced during X-ray irradiation. Therefore, with the purpose to find an aid in the diagnosis of radiation disturbances as well as a clue in the elucidation of the causative factor we performed the present experiment by pursuing the relationship between the radition disturbance and the dosage of X-rays. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=NishishitaSoichi en-aut-sei=Nishishita en-aut-mei=Soichi kn-aut-name=西下創一 kn-aut-sei=西下 kn-aut-mei=創一 aut-affil-num=2 ORCID= en-aut-name=AndoRyo en-aut-sei=Ando en-aut-mei=Ryo kn-aut-name=安東龍 kn-aut-sei=安東 kn-aut-mei=龍 aut-affil-num=3 ORCID= en-aut-name=NobukiShigeo en-aut-sei=Nobuki en-aut-mei=Shigeo kn-aut-name=信木茂生 kn-aut-sei=信木 kn-aut-mei=茂生 aut-affil-num=4 ORCID= en-aut-name=TukamotoIzumi en-aut-sei=Tukamoto en-aut-mei=Izumi kn-aut-name=塚本泉 kn-aut-sei=塚本 kn-aut-mei=泉 aut-affil-num=5 ORCID= en-aut-name=HasigamiTadasi en-aut-sei=Hasigami en-aut-mei=Tadasi kn-aut-name=橋上正 kn-aut-sei=橋上 kn-aut-mei=正 aut-affil-num=6 ORCID= en-aut-name=AkagiKeiko en-aut-sei=Akagi en-aut-mei=Keiko kn-aut-name=赤木瑩子 kn-aut-sei=赤木 kn-aut-mei=瑩子 aut-affil-num=7 ORCID= en-aut-name=WakimotoMasahiro en-aut-sei=Wakimoto en-aut-mei=Masahiro kn-aut-name=脇本正寛 kn-aut-sei=脇本 kn-aut-mei=正寛 aut-affil-num=8 ORCID= en-aut-name=YamamotoKoki en-aut-sei=Yamamoto en-aut-mei=Koki kn-aut-name=山本弘毅 kn-aut-sei=山本 kn-aut-mei=弘毅 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=8 article-no= start-page=3029 end-page=3040 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Irradiation Susceptibility of Cervical Carcinoma, with a Special Reference to the Metastasis to Lymph Nodes kn-title=子宮頸癌の放射線感受性に関する研究 特に転移淋巴節に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=Preoperative roentgen-irradiation (unilaterally 1-12 times) treatment was given to 216 cases with cervical carcinoma, and 24 hours after the completion of irradiation Okabayashi's radical extensive hysterectomy was performed. The author studied the irradiation susceptibility of metastased cancer cells by comparing the original site of cancer with metastased lesions and the metastatic irradiated side with non-irradiated side, with a special emphasis on the mitosis of cancer cells. As for the significance between C.P.L. type (Imai) of the primary cancer and the metastatic foci, the change in the mitotic picture due to roentgen irradiation in C-type metastatic foci is significantly greater than that in L-type metastatic foci; and therefore, the irradiation susceptibility in C-type can be said higher. Namely, in this instance the irradaation susceptibility and the prognosis have the same tendency. As for the relationship between Nagase's classification (Types T, U, V) of the primary cancer and its metastatic foci, the change in mitotic picture due to roentgen irradiation in the case of Type U metastatic focus is greater than in Type T metastatic focus, and the irradiation susceptibility in Type U tends to be higher. In other words, in this instance the irradiation susceptibility is in no way associated with the prognosis. Therefore, it is dangerous to deduce the prognosis from the irradiation susceptibility of cancer cells. Numbers of giant cells appearing due to irradiation increase in proportion to the degree of the destruction of the cancer focus irradiated upon. Therefore, in the observation of dividing cells in the irradiated cancer focus, it is essential to pay attention not only to the change in the number of cells but also to the variety of the degeneration picture. The degree of degeneration in dividing cells increases in propoetion to the irradiation amount, and by a irradiation more than 1,300 r (deep dosis) the mitotic picture changes markedly, thus bringing about the cell disintegration. On applying an irradiation tube on the anterior surface, its lower margin is placed just above the pubic symphysis, and its inner margin is about 2 cm. outside the medial line; and on applying it on the posterior or lateral side, its lower margin is placed on both greater trochanters; and from the posterior side it is irradiated at the angle 20℃ to the side of the head. In other words, it is believed that main lymph nodes in the pelvis are almost all equally irradiated by irradiation at the sites mentioned above. en-copyright= kn-copyright= en-aut-name=OmuraMakio en-aut-sei=Omura en-aut-mei=Makio kn-aut-name=大村真喜雄 kn-aut-sei=大村 kn-aut-mei=真喜雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部産科婦人科学教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=8 article-no= start-page=3001 end-page=3011 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on the Irradiation Susceptibility of Cervical Carcinoma kn-title=子宮頸癌の放射線感受性に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=Since Broders and Martzlff's report on the relation of irradiation susceptibility of the cervical carcinoma with the prognosis, there appeared many studies on the same subject by various investigators. And with the recent reports on the C.P.L. classification and Nagase's classification it has become clearly established that there is a close relationship between the irradiation susceptibility and prognosis. In the present paper are presented the results of observations on histological changes, especially changes in the mitotic picture and the appearance of giant cells, in the tissue specimens prepared before and after irradiation from 205 operable cases with cervical carcinoma, who had been treated with irradiation (mainly bard roentgen and some by radium irradiation) and then operated on by Okabayashi's method during the periodfrom August 1956 to December 1957, and also presented are comparative studies of these results with the CPL classification and Nagase's classification. 1) The histological changes turn generally markedly with incresed amount of radiation, but the change observable in each individual case reveals a marked individualistic difference, yet showing not necessarily any parallelism in the histologicai change with the amount of radiation within the surface dosis of 3,600 r. 2) No specific relationship exists between the histological change and the C.P.L. classification or Nagase's classification. 3) As for the change in the mitotic picture, the normal mitosis is rapidly diminished by irradiation, finally disappearing completely with the increase in the amount of radiation, while on the contrary abnormal mitosis is markedly enhanced by irradiation. 4) As for the relationship between the change in the mitotic picture and the C.P.L. classification, in the case given six roentgen irradiations (surface dosis of 1,800 r.) there is no significant relationship, but in the cases given 12 rounds of irradiation (surface dosis of 3,600 r.) the change in Type C is greater than that in Type L. 5) As regrads the relationship between the chang in the mitotic picture and Nagase's classification, no specific relationship can be recgonized in the cases administered with 6 rounds of irradiation an increase in the appearance of abnormal mitosies in Type T is more pronounced than that in Type U or Type V. 6) Giant cells appear increasingly after six rounds or more of irradiation; and in the cases given 12 rounds of irradiation they appear significantly more numerously in Type C according to the CPL classification while more significantly in Type T according to Nagase's classification. The actions of irradiation on cancer tissue may be roughly divided into a direct action on cancer cells and an indirect action derived from the influences on the local interstitial tissues and on the systemic metabolism. However, it seems that the irradiadiation susceptivility first of all and subsequently the problem related the prognosis can be solved only when these direct and indirect actions are summarily studied. en-copyright= kn-copyright= en-aut-name=MiyakeMasaaki en-aut-sei=Miyake en-aut-mei=Masaaki kn-aut-name=三宅昌秋 kn-aut-sei=三宅 kn-aut-mei=昌秋 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部産科婦人科学教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=8 article-no= start-page=2987 end-page=3000 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Study on the Irradiation Susceptibility of Cervical Carcinoma by Means of Vaginal Contents kn-title=膣内容による子宮頸癌の放射線感受性に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=By giving preoperative roentgen-Irradiation treatment to 225 operable cases of cervical carcinoma, admitted to the Department of Obstetrics and Gynecology, Okayama University Medical School, from August 1, 1956 to December 31, 1957, and later operated upon by Okabayashi's radical extensive hysterectomy, the author carried out the following observations: Namely, by observing changes in the T.P.T. cell count due to roentgen irradiation; the degree of changes in cancer tissue; and R.M. Graham's sensitization response and radiation reaction, and after studying mutual relationship of these, the author obtained the following results. 1. It seems possible to know the roentgen susceptibility of the cancer by observing the manner of the increase brought about by roentgen irradiation in T.P.T. cell count in the vaginal contents. 2. The sensitization response is in no way involved in the cancer-tissue change due to roentgen irradiation, and it seems that the sensitization response is not representing the roentgen susceptibility of the cancer. 3. Radiation reaction fluctuates well correspondingly with the cancer-tissue change brought about by roentgen irradiation, and it seems that the radiation reaction represents the roentgen susceptibility of the cancer. 4. It has been possible to clarify the inter-relationship in the results of Ukida, A. Glucksmann, and R. M. Grahdm, and also it has been possible to explain them without discrepancy. en-copyright= kn-copyright= en-aut-name=IkenoueYoshio en-aut-sei=Ikenoue en-aut-mei=Yoshio kn-aut-name=池上誼郎 kn-aut-sei=池上 kn-aut-mei=誼郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部産科婦人科学教室 END start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue=7-9 article-no= start-page=579 end-page=587 dt-received= dt-revised= dt-accepted= dt-pub-year=1961 dt-pub=19610930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental studies on the effect of exhaustive physical exercise against radiation injury. Part 2 kn-title=運動負荷が放射線障害に及ぼす影響に関する実験的研究 第2編 放射線照射直前又は照射後の運動負荷が,生存率,体重変化に及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=C(57)-Black female mi^e were divided into the next 7 groups for the purpose of examining the effects of the exhaustive physical exercise before and after the irradiation. Group 1. Exercised for 30 minutes directly before the irradiation (RE pre-30 m.) Group 2. Exercised for 1 hour directly before the irradiation (RE pre-1h)Group 3. Exercised for 2 hours directly before the irradiation (RE pre-2h) Group 4. Exercised for 1 hour after the irradiation (RE post) This exercise was continued for 30 days at the rate of 1 hour per day and 6 days per week after irradiation. Group 5. Exercised control (EC) This exercise was the similar as that in Group 4 Group 6. Radiated control (RC) Group 7. "Thyradin" injected (TR) "Thyradin" (thyroid preparation) was injected 0.2 c. c. (contains 10γ of iodine) per 10 grams of body weight, and then the animals were exposed to X-ray on the 7th day after irradiation. Exercised groups were made to run in the cylindrical tread-mill (80 cm in circumference, 8 rotations per minute, i.e. the animals have to run at a speed of 6.4 m per minute). Irradiated groups received 600 r, 660 r and 840 r of X-ray at 99 r per minute. Gas analyses were done in order to evaluate the metabolic level of the exercise on one mouse in each group which was made to run in another tread-mill of the same diameter, rotating in the same speed as one described above, and located in an air-tight chamber shown in fig. 1. The air sample from this chamber was analysed with Scholander's apparatus. This results are as follows: 1) The metabolism increased by the exercise showing 33.85 % (mean) increased of the oxygen consumption. 2) The metabolism was accelerated gradually by the "Thyradin" treatment arriving the maximum arround the 6th day after the injection, showing 42.99 % of the increase of oxygen consumption. 3) The survival rate in the groups which were exercised before the irradiation was higher than that in the group of radiated control and the group exercised after the irradiation. The difference of the survival rate detween the groups exercised bafore the irradiation and the groups exercised after the irradiation was significant (P<0.05). 4) The survival rate in the groups which were exercised before the irradiation was not in proportion to the quantity of the exercise before the irradiation. 5) The metabolism was increased by the injection of "Thyradin" and lowered the survival rate. 6) The weight in the group of radiated control dropped down day by day, but in the group exercised before the irradiation began to recover after three weeks of irradiation. 7) The weight in the group injected "Thyradin" decrease extremely 2 weeks after the irradiation. en-copyright= kn-copyright= en-aut-name=OkahiraKazuma en-aut-sei=Okahira en-aut-mei=Kazuma kn-aut-name=岡平和磨 kn-aut-sei=岡平 kn-aut-mei=和磨 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学教室 END start-ver=1.4 cd-journal=joma no-vol=73 cd-vols= no-issue=7-9 article-no= start-page=553 end-page=578 dt-received= dt-revised= dt-accepted= dt-pub-year=1961 dt-pub=19610930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental studies on the effect of exhaustive physical exercise against radiation injury. Part 1 kn-title=運動負荷が放射線障害に及ぼす影響に関する実験的研究 第1編 放射線照射後の連続的運動負荷が生存率,体重変化及び血液諸成分に及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Guinea pigs were divided into the next four groups for the purpose of examining the effects of exhaustive physical exercise and fatigue after exposing to X-ray. (1) Non treated group (C) (2) Exercised control group (EC) (3) Radiated control group (RC) (4) Radiated exercised group (RE) The X-ray apparatus was operated at. 200 KV, 15 mA, 0.5 mm Copper and 0.5 mm Alminium filtration, 50 cm focus target distance. The dose was 200 r of. X-ray whole body irradiation in dose rate of 80.6 r/min (in the air). Subjects of this experiment were given 30 successive days of swimming at the rate of 30 minutes per day and 5 days per week. The results are as follows: (1) The 30 days survival rate of RE was lower than that of RC. (2) The decreasing rate of the body weight in RE was a little higher than that in RC. (3) The prolongation of the blood clotting time in RE was greater than that in RC. (4) The decreasing rate of red cell count in RE was a little higher than that in RC. In both groups the decreasing rate was the highest on the 14th day after the treatment. (5) The decreasing rate of hemoglobin content in RE was a little higher than that in RC. In both groups the decreasing rate was the highest on the 14th day after the treatment. (6) Reticulocyte count in RE and RC decreased in the beginning, but increased extremely on the 21st day after treatment. Its increasing and decrasing rate in RE was little different from that in RC. (7) The increasing rate of Heinz body in RE was higher than that in RC. (8) The decresing rate of white cell count in RE was not significantly different from that in RC. In both groups the white cell count was at minimum on the 14th day after treatment. (9) Concerning the classification of white cell, i.e. basophile., eosinophile-, neutrophile leucocyte, lymphocyte and monocyte, RE was not significantly different from RC. (10) About the changes of plasma proteins, a) The total protein in RC decreased a little in the beginning, but slightly increased in the latter period. That in RE showed little change in the beginning, and slightly increased in the latter period. Difference between RE and RC was not significant, b) A/G ratio did not change much in the beginning in RC as well as RE, but in the latter period it decreased in RC while increased in RE. c) Albumin didn't show much change in the beginning both in RC and RE, but it decreased a little in the latter period where as in RC it increased in RE. d) α-globulin in RC and RE increased a little after the treatment. Difference between RC and RE was not significant. e) β-globulin in RC decreased a little in the beginning, but increased in the latter period. On the contrary in RE, it decreased extremely in the latter period. f) Fibrinogen in RC and RE increased. Difference between RC and RE was not significant. g) γ-globulin n RC and RE decreased in the beginning. That in RC increased extremely, while in RE continued to decrease in the latter period. en-copyright= kn-copyright= en-aut-name=OkahiraKazuma en-aut-sei=Okahira en-aut-mei=Kazuma kn-aut-name=岡平和磨 kn-aut-sei=岡平 kn-aut-mei=和磨 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部衛生学教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=2 article-no= start-page=399 end-page=411 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Srudies on the Influences of Irradiation upon the Bone Marrow Tissue Culture of Rabbits Part V. Influences of X-Ray on the Bone Marrow Tissue of Rabbit in Fluid Medium kn-title=放射線の家兎骨髄体外組織培養に及ぼす影響に関する研究 第3編 「レ」線の家兎骨髄体外液体培養に及ぼす影響に就て en-subtitle= kn-subtitle= en-abstract= kn-abstract=Using adult rabbits, the author performed the bone-marrow tissue cultures in fluid medium from the rabbits irradiated repeatedly and systemically with 100r of X-ray irradiation, 24-42 times; 300r, 10 times; and 1,000r once only and observed for the periods of 1-30 days; and obtained the following results. 1) In the group repeatedly irradiated wiht 100r X-ray, both the rate of increase of erythrocyte count as well as that of hemoglobin count decreased markedly. 2) In the group subjected to the irradiation of 3000r, the rate of erythrocyte count and that of hemoglobin count likewise decreased markedly. 3) In the group receiving a single irradiation of 1,000r, the rate of erythrocyte count and that of hemoglbin count decreased gradually along with the lapse of time, and both values reached their minimum on the tenth day while by the thirtieth day both were found to be at the normal. 4) In the repeated irradiations as mentioned above, the erythropoietic function is disturbed in parallel with the function of hemoglobin synthesis, whereas in the group subjected to a single irraiation of 1,000r X-ray, the erythropoietic function seems to be affected more markedly than the function of hemoglbin synthesis. Therefore, in the case receiving smaller doses it is assumed that the erythropoietic function is affected prior to the function of hemoglobin synthesis. en-copyright= kn-copyright= en-aut-name=HashimotoSeishi en-aut-sei=Hashimoto en-aut-mei=Seishi kn-aut-name=橋本誠志 kn-aut-sei=橋本 kn-aut-mei=誠志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=2 article-no= start-page=383 end-page=397 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Influences of Irradiation upon the Bone Marrow Tissue Culture of Rabbits Part U. Influences of Radio Isotope P(32) on the Bone Marrow Tissue Culture of Rabbits in Coverslips kn-title=放射線の家兎骨髄体外組織培養に及ぼす影響に関する研究 第2編 放射性同位元素P(32)の家兎骨髄体外被覆培養に及ぼす影響に就て en-subtitle= kn-subtitle= en-abstract= kn-abstract=By injecting 3 mc/kg of radio isotope P(32) once only and observed for the periods of 1-14 days and to other group 800 μc/kg once and observing for the periods of 1-30 days, the author performed cultures of the bone marrow from these rabbits in coverslips and obtained the following results. 1) In the group irradiated with P(32) 3 mc/kg, the relative growth rate, cell density and the wandering velocity of pseudoeosinophils all decreased strikingly; while in the group receiving P(32) 800 μc/kg, these values were found all increased. Namely, in the case receiving a large dosage of P(32) irradiation, the white corpuscle series of the bone marrow show marked disturbances while in the case subjected to a small dosage of the irradiation it is stimulated. 2) The increase in the cell proliferation in the case irradiated with such an amount of P(32) as to cause stimulation seems to precede the increase in the cell functions. 3) Therefore, judging these results along with those in report T, the cell proliferation seems to be more sensitive to the irradiation than the cell functions. 4) As the cell proliferation tends to be affected prior to the cell functions in the both irradiations so far described, the influences of P(32) irradiation on the bone marrow seem not to differ essentially to any great extent from those of X-ray irradiation. en-copyright= kn-copyright= en-aut-name=HashimotoSeishi en-aut-sei=Hashimoto en-aut-mei=Seishi kn-aut-name=橋本誠志 kn-aut-sei=橋本 kn-aut-mei=誠志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=70 cd-vols= no-issue=2 article-no= start-page=369 end-page=381 dt-received= dt-revised= dt-accepted= dt-pub-year=1958 dt-pub=19580228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Influences of Irradiation upon the Bone Marrow Tissue Culture of Rabbits Part I. Influences of X-Ray on the Bone Marrow Tissue Culture of Rabbits in Coverslips kn-title=放射線の家兎骨髄体外組織培養に及ぼす影響に関する研究 第1編 「レ」線の家兎骨髄体外被覆培養に及ぼす影響に就て en-subtitle= kn-subtitle= en-abstract= kn-abstract=With the use of adult rabbits, the author performed the bonemarrow culture in coverslips and obtained from the rabbits irradiated repeatedly and systemically with 100r of X-ray 24-41 times, and 300r of X-ray ten times, and 1,000r of X-ray once and observed the bone marrow from respective groups during the periods ranging 1-30 clays after the irradiation. The results are described in the following. 1) In the group receiving repeatedly and systemically the irradiation of 1000r of X-ray the relative growth rate, cell density, the wandering velocity of pseudoeosinophils all decreased markedly. 2) In the group given the irradiation of 300r X-ray, no sign whatsoever could be recognized as regards the relative growth rate, cell density and the wandering velocity of pseudoeosinophils; and the bone marrow presented aplasia. 3) In the group receiving 1,000r of X-ray irradiation once only, the relative growth rate, cell density and the wandering velocity of pseudoeosinophils all docreased gradually lower with the lapse of time; and all the values presented their minimum on the tenth day but on the thirtieth day it was found that they were all rather increased. 4) Of the disturbances in the bone marrow due to the X-ray irradiation. in the groups receiving repeated irradiation the cell proliferation was disturbed in direct proportion to those of the cell function. In the group receiving a single irradiation of 1,000r, the cell proliferation was disturbed on the second day but it seemed to have a tendency to precede the disturbances of the cell functions. Therefore, it is assumed that in the case receiving a small dose of X-ray irradiation the cell proliferation of bone marrow is disturbed earlier, and the cell functions are diminished later. en-copyright= kn-copyright= en-aut-name=HashimotoSeishi en-aut-sei=Hashimoto en-aut-mei=Seishi kn-aut-name=橋本誠志 kn-aut-sei=橋本 kn-aut-mei=誠志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=10 article-no= start-page=965 end-page=979 dt-received= dt-revised= dt-accepted= dt-pub-year=1963 dt-pub=19631030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relations between Reticulo-endothelial System, Tumor and X-Rays kn-title=網内系機能と悪性腫瘍並びに放射線との関係に就いて 第2編 実験腫瘍(吉田肉腫),網内系,放射線との相関に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=Vol. T The effect given to the blood picture and the function of the reticulo-endothelial system using reticulo-endothelial system blocked by the Indian ink method and also the tumor growth, survival rates and metastasis after transplanting Yoshida sarcoma cells intramusclarlly in the albino-rat thigh were examined. Experiment was done to find out the relations between the reticulo-endothelial system and the latter, which the results were as follows: 1) As formerly reported, the reticulo-endothelial system blocked by the Indian ink method showed anaemia by a certain quantity of ink but it passed by and restored gradually. It showed parallel relation with the function of the reticulo-endothelial system. 2) If the ink was small in quantity, it did not give much effects to tumor growth though the function of the reticulo-endothelial system was low. 3) The reticulo-endothelial system blocked by the Indian ink method had a connection with the growth of tumor to some extent and gave pictures which accelerated its growth. And stromal reaction near the tumor was weak. 4) Using the reticulo-endothelial system blocked by the Indian ink method, the appearance of the reticulo-endothelial cells in the tumor tissue was less compared with the control. Vol. U Chapter 1 To prove the reaction on the X-rays of the reticulo-endothelial system and tumor growths, the author made an experiment based on the idea of tumor-host relationship. X-rays, 600r a day continuing 5 days totalling 3000r, were irradiated into the tumor bed, albino-rat thigh, and then Yoshida sarcoma cells were transplanted on the irradiated part. The influence against tumor growth, survival rates and metastasis were examined and the effects were found as follows: 1) Compared with the control, the tumor growths were restrained in the order of transplanted groups of the next day after irradiation, transplanted groups of 10 days after irradiation, and transplanted groups of 30 days after irradiation. With the survival rates, life extension could be recognized in the same order. 2) Stromal reaction could be strongly found in pre-irradiated groups, especially in these being transplanted the next day. Reticulo-endothelial cells could be found many compared with the control. Above all, it could be presumed that in case of preoperative irradiation, the part of reticulo-endothelial cells which has not been infiltrated by tumor cells shows protection system by stromal reaction. Chapter 2 When the tumor which was transplanted by Yoshida sarcoma cells became a regular induration; the size, the rise and fall, and the survival rates were examined by irradiating 300r a day for 10 days totalling 3000r. The effect showed that when the function of the reticulo-endothelial system which is one of the living body reaction was irradiated after it was restrained, the irradiation effect was less than the non-treated group. Consequently if the function of the reticulo-endothelial system would be irradiated after it was accelerated, it would obtain satisfactory result to medical treatments. en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田邊正忠 kn-aut-sei=田邊 kn-aut-mei=正忠 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=10 article-no= start-page=959 end-page=964 dt-received= dt-revised= dt-accepted= dt-pub-year=1963 dt-pub=19631030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=網内系機能と悪性腫瘍並びに放射線との関係に就いて 第1編 墨汁?塞に依るラッテの血液像,網内系機能並びに吉田肉腫接種後の腫瘍発育,生存率,転移形成に及ぼす影響に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=田邊正忠 kn-aut-sei=田邊 kn-aut-mei=正忠 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=5-7 article-no= start-page=1561 end-page=1567 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600730 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Hemolytic Substance Produced at X-Ray Irradiation Part 2. Qualitative Analysis and Biological Action of the Hemolytic Substance kn-title=放射線照射時に発生する溶血性物質に就いて 第二編 溶血性物質の定性的研究並びに生物作用に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=The cause of irradiation anemia seems to lie in biological phenomena as well as in hemolytic toxin produced by X-Ray irradiation. It has been confirmed that since phospholipid fraction in vivo shows strong toxicity in direct proportion to the dose of X-rays, the actual hemolytic substance is lysolecithin. This substance is proved to give rise to marked morphological changes in hematopoietic organs, and it has also been clarified that the same substance acting on sea-urchin egg brings about a delay in egg division. However the same snbstance does not induce any striking change in the respiratory enzyme system. en-copyright= kn-copyright= en-aut-name=AkagiEiko en-aut-sei=Akagi en-aut-mei=Eiko kn-aut-name=赤木瑩子 kn-aut-sei=赤木 kn-aut-mei=瑩子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=5-7 article-no= start-page=1555 end-page=1560 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600730 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Influences of Unsaturated Fatty Acid Fraction (OX) extracted from the Liver of X-Irradiated Rabbit on the Activity of Succinic dehydrogenase in Subcutaneously-Transplanted Yoshida Sarcoma Cells kn-title=X線照射家兎肝より抽出せる不飽和脂肪酸分画 (OX) の筋肉内移植吉田肉腫細胞のコハク酸脱水素活性に及ぼす影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=In order to study influences of OX on the activity of succinic dehydrogenase in Yoshida sarcoma cells transplanted intramusculrally in the albino-rat thigh, the author injected OX intra-tumorally or intravenously into tumor bearing rats and carried out biochemical and histochemical investigations. The results are as follows: 1. In the cases given direct, intratumoral injection of OX, the activity of succinic dehydrogenase in Yoshida sarcoma cells thus transplanted is decreased, and it recovers very slowly but the same activity in muscle tissues recovers more rapidly. 2. In the histochemical observations when OX is injected intratumorally, central necrosis is increased and also a marked enlargement of bionecrotic foci occurs, but in the outer-most layer colonies of proliferative cells can be recognized. 3. When OX is injected intravenously into tumor bearing rats, the activity of the dephydrogenase is rather increased in tumor tissue, and the part where such increase occurred ultimately tends to become necrotic. In addition, the author discussed briefly about the relation between these changes in the activity of dehydrogenase and OX. en-copyright= kn-copyright= en-aut-name=IguchiYoshiko en-aut-sei=Iguchi en-aut-mei=Yoshiko kn-aut-name=井口与志子 kn-aut-sei=井口 kn-aut-mei=与志子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=5-7 article-no= start-page=1439 end-page=1444 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600730 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Cell Toxin Produced by X-Ray Irradiation Part 2. The Morphological Changes and in Vivo Reactions of the Succinic Dehydrogenase System in Ehrlich Ascites Tumor Cells Induced by the Unsaturated Fatty Acid Fraction Extracted from the Rabbit Liver after X-ray Irradiation kn-title=X線照射時に発生せる細胞毒の研究について 第二編 X線照射家兎より抽出した不飽和脂肪酸分画のEhrlich腹水癌のコハク酸脱水素系に於ける形態学的変化並びに生体内反応について en-subtitle= kn-subtitle= en-abstract= kn-abstract=In Part 1. the author investigatad the effects of the unsaturated fatty acid fraction extracted from the rabbit liver after x-ray irradiation on the succinic dehydrogenase system in Ehrlich ascites tumor cells and in the normal rabbit liver, and it was concluded that although this fraction does not greatly affect the normal liver cells, at a higher concentration it seems to induce cell degeneration which in turn results in a decrease in the respiratory enzyme activity. In the present experiment the author studied the morphological changes brought about by this substance in Ehrlich ascites tumor cell and the in vivo changes induced by it in the succinic dehydrogenase system. In conducting this experiment the results obtained by Yamamoto et al. of our department were referred to. With respect to the morphological changes in the tumor cells, it was observed that this substance acting for a short period of time will accelerate the respiratory enzyme activity transiently while when acting for a longer period, it decreases the activity. These findings agree more or less well with the results in Part 1. Even in the in vivo reactions the respiratory enzyme activity in the tumor cells is elevated temporarily and when acting for a longer period of time this substance decreases the activity. From these findings it is concluded that this substance does elevate the respiratory enzyme activity transiently but when it acts for a longer period of time, it seems to bring about a fall in the activity and further acting directly on the respiratory enzymes it induces the disorder in respiration. en-copyright= kn-copyright= en-aut-name=ShiakuMidori en-aut-sei=Shiaku en-aut-mei=Midori kn-aut-name=塩飽緑 kn-aut-sei=塩飽 kn-aut-mei=緑 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線科医学教室 END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=10 article-no= start-page=799 end-page=804 dt-received= dt-revised= dt-accepted= dt-pub-year=1963 dt-pub=19631030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=About Two Case of Stomach Cancer Patients Complicating Armoured Pericard kn-title=胃癌に合併せる装甲心の2例について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Recently we have been two stomach cancer patients complicating armoured pericard. These two cases are diagnosed by X-ray examination as "armoured pericard" which would be easily differentiated from calcification of mediastinal pleura etc. by means of lateral or oblique projection radiography and tomography, and could be fit for gastrectomy. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=NishishitaSoichi en-aut-sei=Nishishita en-aut-mei=Soichi kn-aut-name=西下創一 kn-aut-sei=西下 kn-aut-mei=創一 aut-affil-num=2 ORCID= en-aut-name=ShiakuTakeru en-aut-sei=Shiaku en-aut-mei=Takeru kn-aut-name=塩飽健 kn-aut-sei=塩飽 kn-aut-mei=健 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=5-7 article-no= start-page=1307 end-page=1311 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600730 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Effects of OX (Uusaturated Fatty Acid Fraction From the Irradiated Rabbit Liver) on the Fertilization and Cleavage of Sea Urchin Egg kn-title=放射線照射家兎肝より抽出せる細胞毒のウニの受精及び卵割に与える影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=The effects of the OX substance, which was extracted from the liver of irradiated rabbits, on the sperm and egg, unfertilized and fertilized eggs of sea urchin (Hemicentrotus pulcherrimus) have been observed. 1. The sperms exposed to OX showed a decreased mortility and lost the ability to stimul to the egg to raise up fertilizing membrane suggesting the inability of giving physical shock to the egg surface or the damage of acrosome. 2. The unfertilized eggs exposed to OX retain the ability of the formation of fertiliging membrane and cleavage but showed remarkable delay in both the length of time for the membrane formation and cleavage. 3. The most sensitive effects on the fertilized eggs have been observed on the initial stage of fusion of sperm and egg nuclei and the metaphase. Immediately after the fertilization in the egg exposed to OX the fusion of sperm and egg nuclei was inhibited and in the cells on metaphase the cleavage was delayed by the prolonged period of transition from metaphase to telophase. 4. From the results with the consideration of the effects of X-rays on cleavage appearing in the past report the authors concluded the OX will be the essential substance representing the effects of X-rays on the cell cleavage. en-copyright= kn-copyright= en-aut-name=SenoSatimaru en-aut-sei=Seno en-aut-mei=Satimaru kn-aut-name=妹尾佐知丸 kn-aut-sei=妹尾 kn-aut-mei=佐知丸 aut-affil-num=1 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=2 ORCID= en-aut-name=UtsumiKozo en-aut-sei=Utsumi en-aut-mei=Kozo kn-aut-name=内海耕慥 kn-aut-sei=内海 kn-aut-mei=耕慥 aut-affil-num=3 ORCID= en-aut-name=ShiwakuMidori en-aut-sei=Shiwaku en-aut-mei=Midori kn-aut-name=塩飽緑 kn-aut-sei=塩飽 kn-aut-mei=緑 aut-affil-num=4 ORCID= en-aut-name=AkagiEiko en-aut-sei=Akagi en-aut-mei=Eiko kn-aut-name=赤木瑩子 kn-aut-sei=赤木 kn-aut-mei=瑩子 aut-affil-num=5 ORCID= en-aut-name=IguchiYoshiko en-aut-sei=Iguchi en-aut-mei=Yoshiko kn-aut-name=井口与志子 kn-aut-sei=井口 kn-aut-mei=与志子 aut-affil-num=6 ORCID= en-aut-name=KobayashiJunichi en-aut-sei=Kobayashi en-aut-mei=Junichi kn-aut-name=小林淳一 kn-aut-sei=小林 kn-aut-mei=淳一 aut-affil-num=7 ORCID= en-aut-name=UenoHisako en-aut-sei=Ueno en-aut-mei=Hisako kn-aut-name=上乃寿子 kn-aut-sei=上乃 kn-aut-mei=寿子 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部病理学教室 END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=7-9 article-no= start-page=743 end-page=746 dt-received= dt-revised= dt-accepted= dt-pub-year=1963 dt-pub=19630930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Primary Reticulum Cell Sarcoma of the Stomach; Report of a Case kn-title=胃細網肉腫症の一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A case of primary reticulum cell sarcoma of the stomach was reported. The patient was a fifty-four year old housewife, with the chief complaints of epigastric pain and anorexia. The roentgen manifestations were consistent with gastric cancer, and total gastrectomy was performed. The lesion was localized in the stomach and histological examination revealed reticulum cell sarcoma. en-copyright= kn-copyright= en-aut-name=ShiakuTakeru en-aut-sei=Shiaku en-aut-mei=Takeru kn-aut-name=塩飽健 kn-aut-sei=塩飽 kn-aut-mei=健 aut-affil-num=1 ORCID= en-aut-name=OginoKeichiro en-aut-sei=Ogino en-aut-mei=Keichiro kn-aut-name=荻野敬一郎 kn-aut-sei=荻野 kn-aut-mei=敬一郎 aut-affil-num=2 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=3 ORCID= en-aut-name=HadaYoshihiro en-aut-sei=Hada en-aut-mei=Yoshihiro kn-aut-name=羽田良洋 kn-aut-sei=羽田 kn-aut-mei=良洋 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=4 article-no= start-page=1269 end-page=1274 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Influences of OX Substance of DNA Content and Mitotic Phase of Subcutaneously-Transplanted Yoshida Sarcoma Cells kn-title=皮下移植吉田腫瘍細胞のDNA量及びMitotic phaseに対するOX物質の影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=After transplanting Yoshida sarcoma cells under the skin of the thigh of hybrid mice, the author injected 0.2cc of 2% unsaturated fatty acid fraction (denominated as OX substance) intramuscularly and observed the changes in the histological picture, in the mitotic phase as well as the changes in the quantity of DNA per cell, along with the lapse of time, and obtained the following results. 1. The histological pictures revealed the phenomena such as an increase in necrotic foci, a general diminution in stainability and indistinct cell boundary. 2. In counting the number of those cells with a relatively strong activity in cancer foci at various mitotic phases, it has been found that from 6 to 12 hours after the OX injection the number of the cells in metaphase is decreased and from 24 hours on the number of such cells approaches the normal. 3. In the estimation of DNA content per cell, from 6 to 12 hours after the OX injection the number of the cells undergoing a relatively active proliferation but with a decreased DNA content tends to increase but after 24 hours the content per cell approaches the normal level. en-copyright= kn-copyright= en-aut-name=IguchiYoshiko en-aut-sei=Iguchi en-aut-mei=Yoshiko kn-aut-name=井口与志子 kn-aut-sei=井口 kn-aut-mei=与志子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=75 cd-vols= no-issue=7-9 article-no= start-page=739 end-page=742 dt-received= dt-revised= dt-accepted= dt-pub-year=1963 dt-pub=19630930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Three Cases of Oesophageal Hiatus Hernia kn-title=最近我々の遭遇せる食道裂孔ヘルニアの3例に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=There are sometimes patients of oesophageal hiatus hernia who visit our clinic complaining gastrointestinal disturbances similiar to stomach cancer or gastric ulcer and symptoms of breast disease. Recently we came upon three of these cases so as would like to report. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=NishishitaSoichi en-aut-sei=Nishishita en-aut-mei=Soichi kn-aut-name=西下創一 kn-aut-sei=西下 kn-aut-mei=創一 aut-affil-num=2 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=3 ORCID= en-aut-name=TanadaMasatada en-aut-sei=Tanada en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部癌研究所/岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=川崎病院/川崎癌研究所放射線科/岡山大学医学部 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=4 article-no= start-page=1203 end-page=1208 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Studies on the Nature of X-Ray Disturbance Part I. Effect of Unsaturated Fatty-Acid Fraction Extracted from X-Ray Irradiated Rabbit-Liver on Succinic Dehydrogenase System of Ehrlich-Ascites-Tumor Cells kn-title=X線照射時に発生せる細胞毒の研究について 第一編 X線照射家兎より抽出した不飽和脂肪酸分画のEhrlich腹水癌,正常肝のコハク酸脱水素系に及ぼす影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=There are many investigations on the disturbances caused by x-rays but these works are consisted mainly of histo-morphological researches and rerely from the viewpoint of the acting mechanism of cells. More recently Lea, Barron et al, however, have studied the histochemical changes in the animals irradiated with x-rays and they have clarified the direct action of x-ray irradiation to a certain extent. In our laboratory Dr. Yamamoto has succeeded in isolating a certain cytotoxin from unsaturated fatty acid fraction, an extract of the liver of the rabbits exposed to x-rays. In the subsequent studies with this cytotoxin it has been found that this substance has an inhibitory action on the mitosis of tumor cells. Therfore, we have carried out a series of experiments to see the effect of this substance, in the presence of succinic dehydrogenase, on the respiration of Ehrlich-ascites-tumor cells. As the result it has been confirmed that this cytotoxin possesses an action as to depress both the respiration of the cancer cell and that of normal liver cells. en-copyright= kn-copyright= en-aut-name=ShiakuMidori en-aut-sei=Shiaku en-aut-mei=Midori kn-aut-name=塩飽緑 kn-aut-sei=塩飽 kn-aut-mei=緑 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=4 article-no= start-page=1197 end-page=1201 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600330 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Effect of the Unsaturated Fatty Acid Fraction from the Liver of Irradiated Rabbit on the Fertilization and Cell Division kn-title=放射線照射家兎肝より抽出せる細胞毒のウニ卵及び精子に与える影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=The effect of unsaturted fatty acid fraction from the liver of irradiated animal on fertilization and cell division of sea urchin egg (Hemicentrotas tulcherrimus) have been observed. The sperms exposed to the substance for 5 minutes decrease in their mortility and lost the fertilization acivitity resuting in the lose of their ability for the formation of fertilizing membrae in eggs. The eggs exposed to this substance after fertilization present the stop or the delay in their cleavage. Such an action on eggs becomes marked when the concentration of this substance increases. The most susceptible stage seems to be the metaphase at which the chromosoms are arrested on the equatolial plate loosing the tendency to move toward the poles. These effects of this substace can be seen even after removing the peroxide as equally in the original substance. en-copyright= kn-copyright= en-aut-name=SenoSatimaru en-aut-sei=Seno en-aut-mei=Satimaru kn-aut-name=妹尾佐知丸 kn-aut-sei=妹尾 kn-aut-mei=佐知丸 aut-affil-num=1 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=2 ORCID= en-aut-name=UtsumiKozo en-aut-sei=Utsumi en-aut-mei=Kozo kn-aut-name=内海耕慥 kn-aut-sei=内海 kn-aut-mei=耕慥 aut-affil-num=3 ORCID= en-aut-name=ShiakuMidori en-aut-sei=Shiaku en-aut-mei=Midori kn-aut-name=塩飽緑 kn-aut-sei=塩飽 kn-aut-mei=緑 aut-affil-num=4 ORCID= en-aut-name=AkagiKeiko en-aut-sei=Akagi en-aut-mei=Keiko kn-aut-name=赤木瑩子 kn-aut-sei=赤木 kn-aut-mei=瑩子 aut-affil-num=5 ORCID= en-aut-name=IguchiYoshico en-aut-sei=Iguchi en-aut-mei=Yoshico kn-aut-name=井口与志子 kn-aut-sei=井口 kn-aut-mei=与志子 aut-affil-num=6 ORCID= en-aut-name=UenoHisako en-aut-sei=Ueno en-aut-mei=Hisako kn-aut-name=上乃寿子 kn-aut-sei=上乃 kn-aut-mei=寿子 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部病理学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部病理学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=3 article-no= start-page=995 end-page=998 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Hemolytic, Anemia-Inducing Substance in Cancer Tissue kn-title=癌組織中の溶血性細胞毒に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=In 1959 we discovered that a hemolytic, anemia-inducing substance is produced in the animals exposed to X-rays. Since then we have found that when this substnce is injeted intravenously into animals, there occur disturbances in the blood, spleen and bone marrow. And also it has become clear that this substance brings about Heinz's body appearance in erythrocytes. As Heinz's body also appears in cancer anemia and it is transformed into hemolysin, it may be assumed that the hemolytic, anemia-inducing substance is contained also in cancer tissue. Upon such assumption we have compared the hemolytic capacity of the extract obtained from the fresh gastric cancer tissue resscted at operation with that of the extract from normal gastric tissue. As the result, we have recognized that this hemolytic, anemia-inducing substance is contained considerably in cancer tissue. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=NobukiSigeo en-aut-sei=Nobuki en-aut-mei=Sigeo kn-aut-name=信木茂生 kn-aut-sei=信木 kn-aut-mei=茂生 aut-affil-num=2 ORCID= en-aut-name=SiakuTakeru en-aut-sei=Siaku en-aut-mei=Takeru kn-aut-name=塩飽健 kn-aut-sei=塩飽 kn-aut-mei=健 aut-affil-num=3 ORCID= en-aut-name=AkagiKeiko en-aut-sei=Akagi en-aut-mei=Keiko kn-aut-name=赤木瑩子 kn-aut-sei=赤木 kn-aut-mei=瑩子 aut-affil-num=4 ORCID= en-aut-name=SiakuMidori en-aut-sei=Siaku en-aut-mei=Midori kn-aut-name=塩飽緑 kn-aut-sei=塩飽 kn-aut-mei=緑 aut-affil-num=5 ORCID= en-aut-name=IgutiYosiko en-aut-sei=Iguti en-aut-mei=Yosiko kn-aut-name=井口与志子 kn-aut-sei=井口 kn-aut-mei=与志子 aut-affil-num=6 ORCID= en-aut-name=TanimotoJunichi en-aut-sei=Tanimoto en-aut-mei=Junichi kn-aut-name=谷本潤一 kn-aut-sei=谷本 kn-aut-mei=潤一 aut-affil-num=7 ORCID= en-aut-name=KojimaSumikazu en-aut-sei=Kojima en-aut-mei=Sumikazu kn-aut-name=小島澄一 kn-aut-sei=小島 kn-aut-mei=澄一 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=72 cd-vols= no-issue=3 article-no= start-page=951 end-page=958 dt-received= dt-revised= dt-accepted= dt-pub-year=1960 dt-pub=19600228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Influences of OX (unsaturated fatty acidextract) on Ehrlich's Ascites Tumor cells kn-title=工ールリッヒ癌に及ぼすOXの影響に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=In view of the fact that there may be two possible actions in radiation distrurbaces in vivo, namely, one acting directly and the other acting indirectly, and on the assumption that these actions, persisting quite a long time after irradiation, induce specific substance in the irradiated nimals, Yamamoto of our department, has succeeded in isolating unsaturated fatty acid substance (OX) specific to the irradiated animals. With the purposa to find out what influences this substance (OX) will have on Ehrlich's ascites tumor cell, the author studied its effect on the number, mitotic phases and DNA ontents of the cancer cells. Test animals used are 80 mice each wighing about 15-20g. To these animals 0.2cc cell suspension of Ehrlich's ascites tumor cell is transplanted intraperitoneally and one week after the transplantation 0.2cc of 2%-, 1%-, 0.5%- OX substance is injected intrapeitoneally to these animals. By observing the changes in the cell counts, mitotic phase, and the DNA contents in each cell (with spectrophotometry) at the intervals of 1, 3, 6, 9, 12, and 24 hours after the injection of OX substance, and the following results were obtained: The number of cancer cells has been found markedly decreased; nomely, after one hour it is down to 78 per cent of the original count; down to 44per cent after 9 hours; and clown to 46.2 per cent after 24 hours. As for the mitotic phases, metaphase, anaphase telophase have been increased and the number of cells undergoing mitosis is diminished. Moreover, as for the DNA contents per cell, there can be observed an increase ni the number of cells with a markedly small amount of DNA, while the cells undergoing duplication due to mitosis have been found decreased in number. From these facts it is concl ded that OX substance acts on Ehrlich's ascites tumor cells as to induce the following disturbances: (1) cell destruction, (2) impairment of the activity in mitotic apparatus, (3) disturbance of the DNA synthesis, and (4) elicits atypical cell divistion. en-copyright= kn-copyright= en-aut-name=ItamiMotoya en-aut-sei=Itami en-aut-mei=Motoya kn-aut-name=伊丹尤也 kn-aut-sei=伊丹 kn-aut-mei=尤也 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=74 cd-vols= no-issue=10-12 article-no= start-page=837 end-page=839 dt-received= dt-revised= dt-accepted= dt-pub-year=1962 dt-pub=19621230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=装甲心の一例に就いて en-subtitle= kn-subtitle= en-abstract= kn-abstract=This case is diagnosed by X-ray examination as armoured pericard which could be easily differentiated from calcification of mediastinal pleura, calcification of coronary blood vessels and calcified focus of the lung by means of oblique projection radiography, roentgen kymography, and tomography. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=塩飽健 kn-aut-sei=塩飽 kn-aut-mei=健 aut-affil-num=1 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=2 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=平松収 kn-aut-sei=平松 kn-aut-mei=収 aut-affil-num=3 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=荻野敬一郎 kn-aut-sei=荻野 kn-aut-mei=敬一郎 aut-affil-num=4 ORCID= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=5 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=77 cd-vols= no-issue=1 article-no= start-page=201 end-page=214 dt-received= dt-revised= dt-accepted= dt-pub-year=1965 dt-pub=19650130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Chemical Protection against Radiation Injuries in Inoculated L-strain Cells in vitro. 11. Protective Effects of s-2-Aminoethylisothiuronium-Br. HBr (AET), Cystamine and Homocysteinethiolactone (HCT) in Inoculated L-strain Cells against X-irradiation kn-title=組織培養法による放射線障害の化学的防禦に関する研究 第2編 培養L-細胞に対するS-2-Aminoethylisothiuronium-Br・HBr(AET),Cystamine及びα-Homocysteinethiolactone(HCT)のX線防禦効果 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The protective effects of AET, Cystamine and HCT against irradiation were studied, comparing the cell population of the treated groups with that of the irradiated control groups on 2 days and 4 days after 400 r or 800 r irradiation. The results were as follows. 1) The protective effect of 10(-4)M AET was observed significantly in both 800 r and 400 r irradiated groups. 2) The protective effect of 10(-3)M AET was observed on 2 days and 4 days after irradiation. 3) The protective effects were not observed in Cystamine and HCT treated groups. en-copyright= kn-copyright= en-aut-name=AndoNorio en-aut-sei=Ando en-aut-mei=Norio kn-aut-name=安東規雄 kn-aut-sei=安東 kn-aut-mei=規雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医学研究科 END start-ver=1.4 cd-journal=joma no-vol=77 cd-vols= no-issue=1 article-no= start-page=181 end-page=200 dt-received= dt-revised= dt-accepted= dt-pub-year=1965 dt-pub=19650130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Chemical Protection against Radiation Injuries in Inoculated L-strain Cells in vitro. 1. Protective Effects of Cysteine and 2-Mercaptoethylamine (MEA) in Inoculated L-strain Cells against X-irradiation kn-title=組織培養法による放射線障害の化学的防禦に関する研究 第1編 培養L-細胞に対するCysteine及び2-Mercaptoethylamine(MEA)のX線防禦効果 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The protective effects of Cysteine and MEA against X-irradiation were investigated, comparing the population of inoculated L-strain cells of the treated groups with that of the irradiated control groups on 2 days and 4 days after 800 r or 400 r irradiation. The results were as follows. 1) The protective effect of 10(-4)M Cysteine was observed significantly on 2 days after 800 r irradiation. 2) Cysteine of 10(-5)M was significantly effective on 2 days and 4 days after 800 r irradiation. 3) MEA seemed to be more effective than Cysteine (not significant). en-copyright= kn-copyright= en-aut-name=AndoNorio en-aut-sei=Ando en-aut-mei=Norio kn-aut-name=安東規雄 kn-aut-sei=安東 kn-aut-mei=規雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医学研究科 END start-ver=1.4 cd-journal=joma no-vol=77 cd-vols= no-issue=1 article-no= start-page=87 end-page=96 dt-received= dt-revised= dt-accepted= dt-pub-year=1965 dt-pub=19650130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Studies on X-ray and Leukemia Part 3. Co-Leukemogenic Action of Croton Oil in the Onset of Leukemia induced by X-ray in RF Strain Mice kn-title=放射線と白血病に関する実験的研究 第3編 X線誘発RF系マウス白血病の発生におけるクロトン油のCo-leukemogenic作用について en-subtitle= kn-subtitle= en-abstract= kn-abstract=With the purpose of studying a possibility of the so-called "two-stage mechanism" in radiation leukemogenesis, a series of studies was conducted to compare the rate of leukemia development, using RF strain mice divided into a set of groups of mice that received one whole body X-irradiation of 150 r, 250 r, 350 r, respectively, and another set of groups similarly irradiated with respective doses and repeatedly painted with 5% croton oil in benzene solution after irradiation. 1. As a result it has been found that in the group receiving 350 r there was no significant difference in the rate of leukemia development between the group receiving the irradiation only and the group that was painted with croton oil solution in addition to the irradiation. 2. In the group that received 250 r, in the group that received croton oil painting immediately after the irradiation or one week after the irradition, there was observed a distinct increase in the rate of leukemia development, while there was no difference between the group that received croton oil painting before the irradiation and the group that received the X-irradiation only. 3. In the groups that received 150 r of the irradiation, leukemia did not develop but it developed only when croton oil was concurrently painted. This finding suggests that leukemia does not develop even when provirus is activated by X-irradiation, if the promoting agent, croton oil is not administered thereafter. 4. In the case when both X-irradiation and croton oil painting were given there could be recngnized leukemias of the so-called thymic type and the non-thymic type in about the same number. 5. In the group given one whoie body irradiation of 250 r and 100 mg of urethane in five separate doses, leukemia developed at a high rate, but in the group given urethane injection alone one of 8 mice developed leukemia. From these results it seems that the "two-stage mechanism" of cancer development as advocated by Berenblum is applicable to the radiation leukemogenesis, and it is thought that X-irradiation acts as an initiator and croton oil as its promotor. In addition, it is presumed that urethane as an initiator has ability to induce leukemia. en-copyright= kn-copyright= en-aut-name=IkejiriKoji en-aut-sei=Ikejiri en-aut-mei=Koji kn-aut-name=池尻孝治 kn-aut-sei=池尻 kn-aut-mei=孝治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=77 cd-vols= no-issue=1 article-no= start-page=59 end-page=69 dt-received= dt-revised= dt-accepted= dt-pub-year=1965 dt-pub=19650130 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experimental Studies on X-ray and Leukemia Part 1. A. Comparative Study of the Effect of X-Irradiation on the Peripheral Blood Picture in Various Strains of Mice kn-title=放射線と白血病に関する実験的研究 第1編 X線照射の末梢血液像に及ぼす影響に関する各種系統マウスの比較研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=As one of the series of studies on radiation leukemogenesis, changes in the peripheral blood picture occurring with lapse of time were pursued with the Cb, D103, StA, and Zb strains of mice (30-50 days old) after a single whole body X-irradiation of 350 r. The results are summarized as follows. 1. Both erythrocyte counts and hemoglobin contents showed the minimum values 2 weeks after the irradiation, and after recovering once they tended to decrease again. Reticulocytes decreased to about 2-4‰ immediately after the irradiation but by the second week they increased to about twice the number in normal condition, and thereafter they returned to the normal count. This change was most marked in the D103 strain, but ultimately the changes in the erythrocyte series presented similar curves in all the four strains mentioned above, and these changes did not differ from those observed in RF strain. 2. The number of leukocytes decressed rapidly to as low as 2,000 immediately after the X-irradiation. The susceptibility to X-ray irradiation was higher in the leukocyte series than in the erythrocyte series. 3. Lymphopoiesis was more sensitive to X-irradiation than myelogenous hematopoiesis, and the decrease of lymphocytes was greater than that of neutrophils, showing a relative neutrophilia for several weeks after the irradiation. 4. After once recovering, the leukocyte counts in the Cb, D103, StA, and Zb strains of mice all did not show such a transient decrease as observed in the preleukemic stage of RF strain about 13 weeks after the irradiation. In addition, lymphocytic leukemia did not develop. 5, In the Cb, D103, StA, and Zb strains irradiated with X-ray there could be recognized no severe eosinophilia such as observed in the RF strain that received X-irradiation. From these findings it has been confirmed that there can be recognized no marked differences in the peripheral blood picture immediately after a single whole body X-irradiation of 350 r between the RF strain of mice that develop leukemia by X-ray, and the Cb, D103, StA. and Zb strains that do not develop leukemia by X-irradiation, but in the observations conducted thereafter along with lapse of time there can be seen several distinct differences in the changes of the leukocyte series between them. en-copyright= kn-copyright= en-aut-name=IkejiriKoji en-aut-sei=Ikejiri en-aut-mei=Koji kn-aut-name=池尻孝治 kn-aut-sei=池尻 kn-aut-mei=孝治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=80 cd-vols= no-issue=3-4 article-no= start-page=453 end-page=459 dt-received= dt-revised= dt-accepted= dt-pub-year=1968 dt-pub=19680430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Compound-Phospholipids formed In Vivo by Irradiation Part 2. Effects of Phospholipids (Extracted In Vivo After Irradiation) on the Culture Cells of Ehrlich Tumor (JTC-11) kn-title=放射線照射により生体内に発生する複合燐脂質に就いて 第2編 複合燐脂質のエールリッヒ培養細胞(JTC-11細胞)に及ぼす影響 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The literature dealing with the nature of irradiation disturbances is replete, but there seems to be no established theory on this phenomenon. It is needless to say that the elucidation of this condition requires further, extensive studies from biochemical, histological and functional aspects, because the irradiation disturbances are not by any means a single entity. Yamamoto of our laboratory states that the compound-phospholipids extracted from tissues of the rabbits exposed to total body irradiation possesses hemolytic and cytolytic effects similar to the effects of irradiation itself. In view of this, the present experiment was conduced in order to observe what effects such an extract would have on the growth of Ehrlich tumor culture cells (JTC 11, strain maintained in the laboratory of Cancer Institute, Okayama Univ.) These cells were cultured in the media containing the aforementioned phospholipids extract in the concentration of 0.1% or 0.5% , and for the control the phospholipids extracted from non-irradiated rabbits was added to the medium in the same concentration. The percentage of degneration of Ehrlich tumor cells was calculated at intervals of one, 3, and 6 hours after the addition of the extract. Two days after the start of culture, the extract was added to the medium, and its effect on the proliferation of Ehrlich cells was studied on the fourth day of the addition of extract. Similarly, morphological changes of Ehrlich cells were observed by electron microscopy at the intervals of 3, 12, 24 and 48 hours after the addition of the extract. As a result it was found that the phospholipids substance extracted from the irradiated rabbit showed a greater degenerative effect and stronger inhibition on the culture cells as well as it elicited more marked morphological changes than the extract from non irradiated rabbit. From this, it is obvious that the extract of the irradiated rabbit has the effect to inhibit the cell growth and destroy the cells just as has been demonstrated in Part 1, which is similar to the disturbances brought about by irradiation. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=合燐脂質のエールリッヒ培養細胞 END start-ver=1.4 cd-journal=joma no-vol=80 cd-vols= no-issue=3-4 article-no= start-page=379 end-page=386 dt-received= dt-revised= dt-accepted= dt-pub-year=1968 dt-pub=19680430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Nature of Heinz Bodies Part 2. Biological Properties on Heinz Bodies kn-title=Heinz小体の性格に関する研究 第2編 Heinz小体の生物学的性格について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Fatty acids extracted from Heinz bodies were aided to Ehrlich ascites tumor cells and HeLa cells in tissue culture at various final concentrations of 0.2, 0.1, 0.05, 0.025%, and their effects on these cultured cells were morphologically observed. It was shown that fatty acids derived from Heinz bodies exerted as nearly a potent cytotoxicity as OX substance oa the cultured tumor cells. At the concentration of 0.2 and 0.1%, immediately following thier addition, almost all the cells showed marked degenerative changes such as bubbling and blister formation, lipid granulation in the cytoplasm and pyknosis of the nuclei and this was soon followed by cell floating and death. And even at the lower concentration of 0.05 and 0.025% the cell degeneration was observed in 3 hours and 6 hours respectively and became floating within 24 hours. From these results, it is considered that the formation of Heinz bodies may be a biological reaction as the body defense mechanism, en-copyright= kn-copyright= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=79 cd-vols= no-issue=9-10 article-no= start-page=771 end-page=777 dt-received= dt-revised= dt-accepted= dt-pub-year=1967 dt-pub=19671030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Eosinophilic Gastritis Report of two Cases kn-title=EOSINOPHILIC GASTRITISと考えられる二例について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Recently, as we have encountered two cases of eosinophilic gastritis, we have described about these X-ray findings etc.. And attention is called to the feasibility of clinical and roentgenographic diagnosis. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=NishishitaSoichi en-aut-sei=Nishishita en-aut-mei=Soichi kn-aut-name=西下創一 kn-aut-sei=西下 kn-aut-mei=創一 aut-affil-num=2 ORCID= en-aut-name=HiramatuOsamu en-aut-sei=Hiramatu en-aut-mei=Osamu kn-aut-name=平松収 kn-aut-sei=平松 kn-aut-mei=収 aut-affil-num=3 ORCID= en-aut-name=IidaSrosuke en-aut-sei=Iida en-aut-mei=Srosuke kn-aut-name=飯田荘介 kn-aut-sei=飯田 kn-aut-mei=荘介 aut-affil-num=4 ORCID= en-aut-name=NokiharaYosimasa en-aut-sei=Nokihara en-aut-mei=Yosimasa kn-aut-name=軒原良正 kn-aut-sei=軒原 kn-aut-mei=良正 aut-affil-num=5 ORCID= en-aut-name=KumadaYasumasa en-aut-sei=Kumada en-aut-mei=Yasumasa kn-aut-name=久萬田泰昌 kn-aut-sei=久萬田 kn-aut-mei=泰昌 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=80 cd-vols= no-issue=3-4 article-no= start-page=365 end-page=378 dt-received= dt-revised= dt-accepted= dt-pub-year=1968 dt-pub=19680430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Nature of Heinz Bodies Part 1. Biochemical Properties of Heinz Bodies kn-title=Heinz小体の性格に関する研究 第1編 Heinz小体の生化学的性格について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Heinz bodies produced in vitro by X-irradiation or hydroxylamine hydrochloride were separated and collected. The lipids extracted from these Heinz bodies were analyzed as to their lipid and fatty acid composition by thin layer chromatography and gas-liquid chromatography. The purpose of the present experiment is to compare the composition of lipids and fatty acids in the Heinz bodies produced by the two different methods. In addition, the membranes of the untreated red cells were similarly treated and analyzed for comparison. 1. It was found that there were differences in the composition of lipids and fatty acids derived from Heinz bodies under different circumstances in which they were formed, even though they might appear morphologically identical on stained preparations. Namely, Heinz bodies contained a lipid fraction whose chemical composition was not necessarily the same and it was suggested that they were the degenerative products having the same characteristics. 2. Analysis of lipids of Heinz bodies indicated a marked decrease of the phosphatidyl ethanolamine ratio in comparison with the lipid fraction of the normal red cell membranes. 3. With respect to the fatty acid composition of Heinz bodies, there were a decrease of the stearic acid ratio and an increase of the oleic and linoleic acid ratios, resulting in a marked increase of the total unsaturated fatty acid ratio. 4. The development of X-irradiation anemia is due not only to an impaired erythropoiesis in the hematopoietic tissue but to an accelerated destruction of red cells in the peripheral blood. It is postulated that the peripheral red cells are rendered fragile by X-irradiation through an alteration of the lipid composition ratio of the cell membrane. en-copyright= kn-copyright= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=79 cd-vols= no-issue=9-10 article-no= start-page=727 end-page=731 dt-received= dt-revised= dt-accepted= dt-pub-year=1967 dt-pub=19671030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Three Cases what Appeared to be kn-title=Porzellangallenblaseと考へられる3例について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Present paper describes the findngs of three cases what appeared to be the case of "Porcelain gallbladder" showing the X-ray picture similar to gall stones in the resected bladder and Calcium deposite on the bladder wall. It was in 1926 that "porcelain gallbladder" case was first reported by Florcken. Since then there appeared reports of such cases by Yamamoto, Niizuma and others, but this is a relatively rare diseases. It is sometimes accompanied by gall stones and in other cases without any stones. In the diagnosis of this disease by X-ray it is possible to identify this case by the roentgenograms of affected field and also by tomography of that region. We are able to examine three cases that we encountered by simple X-ray pictures, X-ray pictures with contrast medium as well as by tomographic pictures of the affected region. Some discussion was made comparing the findings of our cases with those available in literature. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=2 ORCID= en-aut-name=NomaShinya en-aut-sei=Noma en-aut-mei=Shinya kn-aut-name=野間新也 kn-aut-sei=野間 kn-aut-mei=新也 aut-affil-num=3 ORCID= en-aut-name=KumadaYasumasa en-aut-sei=Kumada en-aut-mei=Yasumasa kn-aut-name=久萬田泰昌 kn-aut-sei=久萬田 kn-aut-mei=泰昌 aut-affil-num=4 ORCID= en-aut-name=NokiharaYoshimasa en-aut-sei=Nokihara en-aut-mei=Yoshimasa kn-aut-name=軒原良正 kn-aut-sei=軒原 kn-aut-mei=良正 aut-affil-num=5 ORCID= en-aut-name=FurukawaSumako en-aut-sei=Furukawa en-aut-mei=Sumako kn-aut-name=古川須磨子 kn-aut-sei=古川 kn-aut-mei=須磨子 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=79 cd-vols= no-issue=5-6 article-no= start-page=417 end-page=424 dt-received= dt-revised= dt-accepted= dt-pub-year=1967 dt-pub=19670630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Protective Effect of Glntathione to X-ray Radiation kn-title=Glutathione(タチオン)の放射線防護効果について en-subtitle= kn-subtitle= en-abstract= kn-abstract=There are many works dealing with protective effect of glutathione against Xray radiation, but most of them are used subcutaneous or intraperintoneal injection of glutathione to a single large dose of X-ray irradiation. It is reportet by various investigators that the dosage required to yield the protective effect to X-ray irradiation is about 10 mg 〜 25mg/mouse. In a point of view that glutathione is generally used intravenously in clinics, the author has verified that such an injection given just before the X-irradiation proves to be most effective, As for the minimal optimal dosage of glutathione to yield its protecthive effect it has been found to be 100 mg/kg or 2.5 mg/mouse in average in my experiment. From the survival rate of animals tested, changes in their body weight and changes in the blood picture of rabbits, it has been proven that a considerably smaller dosage of glutathione injected intravenously is effective as compared with generally given subcutaneously or intraperitoneally. It is noteworthy that, whereas there can be observed no significant difference in the protective effect between the test groups and the control group (X-ray irradiation only), when glutathione injected to whole body irradiated rabbits just before a single large dose, a considerable protective effect could be obtained in the doses of 100 mg/kg injected into the aural vein for consecutive days just before 100 R/day irradiation. This has been verified by the changes observed in the numbers of lymphocytes, leukecytes as well as erythrocytes. It has been also demonstrated that, while a single dose of 100 mg/kg glutathione injected intravenously just before a single large dose of 1,000 R does not show any protective effect, the same dose of glutathions injected intravenously once a day consecutively just before X-irradiation of 100 R/day yields a considerable protecthive effect. In above mention, I think that there are some clinical significans. en-copyright= kn-copyright= en-aut-name=KawaseEtsuro en-aut-sei=Kawase en-aut-mei=Etsuro kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線教室 END start-ver=1.4 cd-journal=joma no-vol=82 cd-vols= no-issue=11-12 article-no= start-page=503 end-page=509 dt-received= dt-revised= dt-accepted= dt-pub-year=1970 dt-pub=19701230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Differential Diagnosis by Scintigram of Thyroid Gland kn-title=甲状腺腫瘍のシンチグラムについて en-subtitle= kn-subtitle= en-abstract= kn-abstract=Possiblity of differential diagnosis by means of the scintigram of thyroid gland was investigated with 15 cases with chronic inflammation, 54 with benign tumor, 22 with malignant tumor as the subjects of the study. The results are briefly summarized as follows. 1) In chronic inflammatory diseases most cases show an irregularity of the color band, and the lesion site is mostly located in the upper pole followed by the lower pole. 2) In cases of benign tumor warm nodules are decidedly predominant as compared with other diseases, and the margin is mostly either sharp or diffuse, especially sharp one in benign tumor than in malignant one. The peripheral contour is mostly concave. Enlargement of the lesion area is more often observed than in other diseases, and this tendency is especially marked in warm nodule. There can be often observed oppressive deformation. There is no difference of the color level between the right and the left sides. Lesion site does not differ from the right to the left side and it is mostly on the right exterior side and the left lower pole. 3) In malignant tumor, most cases show a large lesion. Ones with irregular margin are more numerous than in other diseases, but here it requires differentiation from inflammation. There is no swelling on the sideof lesion. The oppressive deformity is not so frequent as in benign cases. The affected side in most cases shows a lower color level as compared with healthy side. The lesion site in this case is mostly located in the upper pole. en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=1 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=2 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=3 ORCID= en-aut-name=WatanabeSetsuo en-aut-sei=Watanabe en-aut-mei=Setsuo kn-aut-name=渡辺節生 kn-aut-sei=渡辺 kn-aut-mei=節生 aut-affil-num=4 ORCID= en-aut-name=HaisaYoshio en-aut-sei=Haisa en-aut-mei=Yoshio kn-aut-name=羽井佐芳雄 kn-aut-sei=羽井佐 kn-aut-mei=芳雄 aut-affil-num=5 ORCID= en-aut-name=KumadaYasumasa en-aut-sei=Kumada en-aut-mei=Yasumasa kn-aut-name=久万田泰昌 kn-aut-sei=久万田 kn-aut-mei=泰昌 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=79 cd-vols= no-issue=3-4 article-no= start-page=181 end-page=187 dt-received= dt-revised= dt-accepted= dt-pub-year=1967 dt-pub=19670430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Changes Induced by Bodily Irradiation in Fatty Acid Composition of Organs and Serum Part V. Changes of long-chain fatty acid composition induced by irradiation in the serum of the patients with breast cancer kn-title=放射線生体照射の各臓器構成高級脂肪酸に及ぼす影響について 第3編 乳癌患者血清中高級脂酸の術前放射線治療前後における変動について en-subtitle= kn-subtitle= en-abstract= kn-abstract=With the purpose to study the changes of long-chain fatty acid composition in the serum of the breast cancer patients after radiation therapy, total fatty acids in the serum of the patients with breast cancer, both before and after the radiation teatment, were separated and identified by the the gas-liquid chromatography. The results of the study may briefly be summarized as follows. 1. The total fatty acid composition in the serum at the time when the tumor has grown smaller approaches the level of normal persons in contrast to the level before the radiation therapy. 2. It is considered that the radiation therapy is a success when the polyunsaturated fatty acids, especially linoleic and arachidonic acids are increased and saturated fatty acids are decreased. en-copyright= kn-copyright= en-aut-name=KatsumataNaomi en-aut-sei=Katsumata en-aut-mei=Naomi kn-aut-name=勝俣直躬 kn-aut-sei=勝俣 kn-aut-mei=直躬 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=79 cd-vols= no-issue=3-4 article-no= start-page=175 end-page=180 dt-received= dt-revised= dt-accepted= dt-pub-year=1967 dt-pub=19670430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Changes Induced by Bodily Irradiation in Fatty Acid Composition of Organs and Serum Part U. Effect of X-irradiation on the fatty acid composition in the mice transplanted with solid Ehrlich carcinoma kn-title=放射線生体照射の各臓器構成高級脂肪酸に及ぼす影響について 第2編 X線照射の担癌動物構成高級脂肪酸に及ぼす影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=In order to study the effect of X-irradiation on the composition of fatty acids in the body of cancer bearing animals, at first solid Ehrlich carcinoma was transplanted into the right leg of mice and then 500 R/day of X-rays were irradiated on the right leg of the animals consecutively for 10 days (total dosage 5,000R). The animals were divided into three groups of the irradiated cancer bearing mice, non-irradiated cancer bearing mice and normal mouse control group. The fatty acid extraction was carried out by the method of Folch et al with (1) tumor and right leg muscle, (2) serum, and (3) liver, of each group, and the determination of the fatty acid composition was made by the gas-liquid chromatography. 1. As the result it was found that the tumor tissue of the irradiated group revealed a greater quantity of linoleic acid than that of the non-irradiated cancer bearing group. 2. The solid Ehrlich carcinoma of the right leg contained a larger amount of stearic acid than that in the right leg muscle of normal mice. 3. As for the composition of total fatty acids in the liver and the serum, the percentage of linoleic acid was found greatest in (1) the control group of normal mice, followed by (2) irradiated tumor bearing mice, and (3) non-irradiated tumor bearing mice in the order mentioned. 4. There seems to be some correlation between the cessation of tumor growth by irradiation and the distribution of linoleic acid. en-copyright= kn-copyright= en-aut-name=KatsumataNaomi en-aut-sei=Katsumata en-aut-mei=Naomi kn-aut-name=勝俣直躬 kn-aut-sei=勝俣 kn-aut-mei=直躬 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=79 cd-vols= no-issue=3-4 article-no= start-page=167 end-page=173 dt-received= dt-revised= dt-accepted= dt-pub-year=1967 dt-pub=19670430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Changes Induced by Bodily Irradiation in Fatty Acid Composition of Organs and Serum Part T. Changes in the long chain fatty acid of the rabbit induced by a relatively minute quantity of (32)p-lebeled phosphate kn-title=放射線生体照射の各臓器構成高級脂肪酸に及ぼす影響について 第1編 比較的小線量β線体内照射の生体内脂肪酸構成に及ぼす影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=For the purpose to study changes in the compostion of the long-chain fatty acids induced by a relatively minute quantity of (32)P-radiation of the body, 500 μCi/kg of Na(2)H(32)PO(4) were injected intravenously into normal rabbits and the internal organs and the serum were taken out at intervals of 24, 48 and 72 hours after the injection, and studied the composition by means of gas-chromatography. The results are briefly summarized in the following. 1. As the result it was found that the distribution of (32)P in the organs was in the descending order of liver→kidney→spleen→bone marrow. 2. The fatty acid composition in each of these organs as well as in the serum is affected by beta-ray irradiation of a relatively minute dose. 3. There can be observed rhythmic fluctuations in the composition even of the one and the same fatty acid (e. g. C(18:2)) which is specific to each organ. 4. It is difficult to determine the changes in the composition of the long-chain fatty acids induced by (32)P labeled phosphate simply on the basis of gas- chromatographic study conducted at any unit time interval. en-copyright= kn-copyright= en-aut-name=KatsumataNaomi en-aut-sei=Katsumata en-aut-mei=Naomi kn-aut-name=勝俣直躬 kn-aut-sei=勝俣 kn-aut-mei=直躬 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=79 cd-vols= no-issue=1-2 article-no= start-page=97 end-page=102 dt-received= dt-revised= dt-accepted= dt-pub-year=1967 dt-pub=19670228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Report of Lymphosarcoma of Jejunum kn-title=空腸リンパ肉腫の一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=we encountered a case (47-years male) supected of lymphosarcoma of jejunum by our preoperative X-ray examination, and confirmed the case to be truely of lymphosarcoma of jejunum at operation. Some discussion is made on this case. It is the fourth such cases so far reported in Japan. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=InoueKeizo en-aut-sei=Inoue en-aut-mei=Keizo kn-aut-name=井上圭三 kn-aut-sei=井上 kn-aut-mei=圭三 aut-affil-num=2 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=3 ORCID= en-aut-name=KatsumataNaomi en-aut-sei=Katsumata en-aut-mei=Naomi kn-aut-name=勝俣直躬 kn-aut-sei=勝俣 kn-aut-mei=直躬 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=82 cd-vols= no-issue=5-6 article-no= start-page=249 end-page=255 dt-received= dt-revised= dt-accepted= dt-pub-year=1970 dt-pub=19700630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Discussion on Pancreatic Calculus from Aspects of Roentgenology kn-title=膵臓結石症のレ線学的考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The diagnosis of disseminated parapancreatic calculus is relatively easy from its specific roentgenogram, but in those cases with little roentgenographic shadow or with a solitary shadow it becomes quite difficult. Hence in the latter cases it is necessary to distinguish it from bilestone, kidney stone, peritoneal calcified lymph node, splenic venous thrombus, or duodenal diverticulosis. Therefore, for the diagnosis of the parapancreatic calculus it is important to take a single roentgenogram of the entire abdomen as well as lateral views of the abdomen, the combination of which would afford us to identify the parapancreatic calculus from the density of its shadow, its site and its size. We have recently encountered three patients with pancreatic calculus and present our observations of the cases as well as some remarks on them from the aspects of roentgenology. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=2 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=3 ORCID= en-aut-name=KumadaYasumasa en-aut-sei=Kumada en-aut-mei=Yasumasa kn-aut-name=久萬田泰昌 kn-aut-sei=久萬田 kn-aut-mei=泰昌 aut-affil-num=4 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=5 ORCID= en-aut-name=WatanabeSetsuo en-aut-sei=Watanabe en-aut-mei=Setsuo kn-aut-name=渡辺節生 kn-aut-sei=渡辺 kn-aut-mei=節生 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=82 cd-vols= no-issue=3-4 article-no= start-page=91 end-page=99 dt-received= dt-revised= dt-accepted= dt-pub-year=1970 dt-pub=19700430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Histochemical studies on the irradiation carcinoma of the uterine cervix kn-title=放射線照射子宮頸癌の組織化学的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Histological and histochemical changes of the cervix by irradiation were investigated on 16 cases of carcinoma of the cervix. Maximum surface dose, 2,000-6,000R., was applied to the cervix with a special colpostat followed by radical hysterectomy 1-10 days later. The difference between irradiated areas and non irradiated areas was studied with following results. 1) The activity of non specific esterase increased in irradiated areas with expectation of a useful indicator of radiosensitivity. 2) SDH, LDH and G-6-P DH showed no change in their activity after irradiation. 3) The appeareance of mast cells has some relation with histological radiation effect. Increase of mast cells in number was noticed in good histological response. en-copyright= kn-copyright= en-aut-name=HashimotoTakeo en-aut-sei=Hashimoto en-aut-mei=Takeo kn-aut-name=橋本威郎 kn-aut-sei=橋本 kn-aut-mei=威郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部産科婦人科教室 END start-ver=1.4 cd-journal=joma no-vol=86 cd-vols= no-issue=7-8 article-no= start-page=293 end-page=298 dt-received= dt-revised= dt-accepted= dt-pub-year=1974 dt-pub=19740830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Three Early Gastric Cancers of Superficial Depressive Type on the Greater Curvature kn-title=胃大弯側陥凹性早期癌の3症例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=With advance in the double irridigoradiographic technique the detection of early gastric cancer has markedly increased. However, early gastric cancer of superficial depressive type on the greater curvature, because of the difficulty in its discovery due to the specificity of its site and its low incidence, seems to be relatively rare. In spite of this rarity, recently we encountered superficial depressive cancers at the corpus, the angulus and the antrum one each at respective site, about which we reported with some comments on each. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=2 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=3 ORCID= en-aut-name=OkadaNaoko en-aut-sei=Okada en-aut-mei=Naoko kn-aut-name=岡田直子 kn-aut-sei=岡田 kn-aut-mei=直子 aut-affil-num=4 ORCID= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=5 ORCID= en-aut-name=TakagiHisao en-aut-sei=Takagi en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=6 ORCID= en-aut-name=IidaSosuke en-aut-sei=Iida en-aut-mei=Sosuke kn-aut-name=飯田荘介 kn-aut-sei=飯田 kn-aut-mei=荘介 aut-affil-num=7 ORCID= en-aut-name=OritaKunzo en-aut-sei=Orita en-aut-mei=Kunzo kn-aut-name=折田薫三 kn-aut-sei=折田 kn-aut-mei=薫三 aut-affil-num=8 ORCID= en-aut-name=KanedaShoken en-aut-sei=Kaneda en-aut-mei=Shoken kn-aut-name=金田象顕 kn-aut-sei=金田 kn-aut-mei=象顕 aut-affil-num=9 ORCID= en-aut-name=KondoKeiji en-aut-sei=Kondo en-aut-mei=Keiji kn-aut-name=近藤慶二 kn-aut-sei=近藤 kn-aut-mei=慶二 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第1外科教室 affil-num=9 en-affil= kn-affil=岡山大学医学部第1外科教室 affil-num=10 en-affil= kn-affil=高知県立中央病院外科 END start-ver=1.4 cd-journal=joma no-vol=81 cd-vols= no-issue=3-4 article-no= start-page=143 end-page=150 dt-received= dt-revised= dt-accepted= dt-pub-year=1969 dt-pub=19690430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the Role of Virus in the Development of Leukemia by X-ray-iradiation Report U. Electromicroscopic Demonstration of Virus Particles in the X-ray Induced RF Mouse Leukemia kn-title=放射線による白血病の発生におけるウイルスの役割に関する研究 第U編 X線誘発RFマウス白血病におけるウイルス粒子の電子顕微鏡的証明 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Electromicroscopic studies on the lymph nodes of RF mice with X-ray induced leukemia revealed in intercellular spaces round virus particles, 100 mμ in average diameter, each consisting of an outer membrane and a nucleoid body. They belong to C type virus particles according to the classification of oncogenic viruses by Bernhard, et al or Hiraki, et al. The virus particles showed an identical morphology and process of formation with those of spontaneous leukemic virus. This present report combined with successful implantation of cell-free filtrate from leukemic mice reported in the previous paper gives firmer ground to the idea that inactive virus latent in normal RF mice through vertical transmission was activated by X-ray to act on normal cells to transform into leukemic cells. en-copyright= kn-copyright= en-aut-name=OkadaNaoko en-aut-sei=Okada en-aut-mei=Naoko kn-aut-name=岡田直子 kn-aut-sei=岡田 kn-aut-mei=直子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部平木内科教室 END start-ver=1.4 cd-journal=joma no-vol=86 cd-vols= no-issue=5-6 article-no= start-page=221 end-page=229 dt-received= dt-revised= dt-accepted= dt-pub-year=1974 dt-pub=19740630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Diagnosis of Pancreatic Diseases by Scintigraphy kn-title=膵臓シンチグラフィーによる膵疾患の診断 en-subtitle= kn-subtitle= en-abstract= kn-abstract=With 63 cases on whom we performed the scintigraphy of pancreatic diseases, we studied the possiblity of differential diagnosis and oter points relevant to the diagnosis in this disease group by comparing retrospectively clinical findings with postoperative findings of these cases, and arrived at the conclusions as follows: 1) For the scintigraphy of pancreas, scinticamera is excellent, and it is especially useful to take consecutive pictures at intervals of 10 minutes each for one hour with this camera after injecting (75)Se-methionine. 2) The major cases of the pancreas that gives normal visualization can be considered as normal, but as normal pictures can be obtained even in the cases of chronic pancreatitis. There are some cases where differential diagnosis between the two disease groups is difficult by scintigraphic finding. 3) In the case of a focal decrease of uptake first of all cancer can be suspected. However, there are cases where differentiation from chronic pancreatitis is difficult. In such instances, about half of the cases demonstrating roentgenologically calcification proves to be of chronic, calcified pancreatitis, but excluding these cases the percentage of cancer cases is high. 4) Among those cases showing pancreas in scintigram faint or nonvisible, there were two cases out of 3 where chronic pancreatitis was complicated with calcification. Excluding the two cases, cancer occupies a decidedly high percentage, and the cancer is mostly located around the head of pancreas, indicating that pathologic changes have invaded main pancreatic ducts. 5) There were 7 cases of chronic, calcified pancreatitis, one case giving normal pancreatitis, one case giving normal scitigraphic findings, 4 cases a focal decrease of uptake, and two cases showing the pancreas faint or nonvisible. en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=1 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=2 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=3 ORCID= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=4 ORCID= en-aut-name=TakagiHisao en-aut-sei=Takagi en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=5 ORCID= en-aut-name=HaisaYoshio en-aut-sei=Haisa en-aut-mei=Yoshio kn-aut-name=羽井佐芳雄 kn-aut-sei=羽井佐 kn-aut-mei=芳雄 aut-affil-num=6 ORCID= en-aut-name=KumadaYasumasa en-aut-sei=Kumada en-aut-mei=Yasumasa kn-aut-name=久万田泰昌 kn-aut-sei=久万田 kn-aut-mei=泰昌 aut-affil-num=7 ORCID= en-aut-name=WakabayashiHiroshi en-aut-sei=Wakabayashi en-aut-mei=Hiroshi kn-aut-name=若林弘 kn-aut-sei=若林 kn-aut-mei=弘 aut-affil-num=8 ORCID= en-aut-name=HashimotoGonosuke en-aut-sei=Hashimoto en-aut-mei=Gonosuke kn-aut-name=橋本郷之介 kn-aut-sei=橋本 kn-aut-mei=郷之介 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=86 cd-vols= no-issue=3-4 article-no= start-page=133 end-page=138 dt-received= dt-revised= dt-accepted= dt-pub-year=1974 dt-pub=19740430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Case with Esophageal Leiomyoma kn-title=食道平滑筋腫の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Leiomyoma of the esophagus is a rare lesion. On this case that we reported, the right oblique chest radiogram showed the soft tissue mass in the mediastinum. The diagnosis was made by the barium swallow study. In this report, we chiefly discussed about the radiologic findings of the esophageal leiomyoma and differential diagnosis with extraesophageal tumors. en-copyright= kn-copyright= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=1 ORCID= en-aut-name=WatanabeSetsuo en-aut-sei=Watanabe en-aut-mei=Setsuo kn-aut-name=渡辺節生 kn-aut-sei=渡辺 kn-aut-mei=節生 aut-affil-num=2 ORCID= en-aut-name=TakagiHisao en-aut-sei=Takagi en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=3 ORCID= en-aut-name=EbaraKazuhiko en-aut-sei=Ebara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=4 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=5 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=6 ORCID= en-aut-name=IidaSosuke en-aut-sei=Iida en-aut-mei=Sosuke kn-aut-name=飯田荘介 kn-aut-sei=飯田 kn-aut-mei=荘介 aut-affil-num=7 ORCID= en-aut-name=FujiwaraKanzi en-aut-sei=Fujiwara en-aut-mei=Kanzi kn-aut-name=藤原幹治 kn-aut-sei=藤原 kn-aut-mei=幹治 aut-affil-num=8 ORCID= en-aut-name=HaisaYoshio en-aut-sei=Haisa en-aut-mei=Yoshio kn-aut-name=羽井佐芳雄 kn-aut-sei=羽井佐 kn-aut-mei=芳雄 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=86 cd-vols= no-issue=3-4 article-no= start-page=127 end-page=132 dt-received= dt-revised= dt-accepted= dt-pub-year=1974 dt-pub=19740430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Case with Leiomyoma of the Jejunum kn-title=空腸平滑筋腫の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Leiomyoma of the small intestine is a rare lesion, and most cases are found during operation and during autopsy. This patiant who we reported had a history of melena. Oval filling defect was detected in the jejunum by means of conventional barium examination. The histologic type of this neoplasm could be suggested by its radiologic findings and probed by operation. en-copyright= kn-copyright= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=1 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=2 ORCID= en-aut-name=KawaseEtsuro en-aut-sei=Kawase en-aut-mei=Etsuro kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=3 ORCID= en-aut-name=EbaraKazuhiko en-aut-sei=Ebara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=4 ORCID= en-aut-name=TakagiHisao en-aut-sei=Takagi en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=5 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=6 ORCID= en-aut-name=KanedaShoken en-aut-sei=Kaneda en-aut-mei=Shoken kn-aut-name=金田象顕 kn-aut-sei=金田 kn-aut-mei=象顕 aut-affil-num=7 ORCID= en-aut-name=OritaKunzo en-aut-sei=Orita en-aut-mei=Kunzo kn-aut-name=折田薫三 kn-aut-sei=折田 kn-aut-mei=薫三 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部第一外科教室 affil-num=8 en-affil= kn-affil=岡山大学医学部第一外科教室 END start-ver=1.4 cd-journal=joma no-vol=83 cd-vols= no-issue=11-12 article-no= start-page=545 end-page=552 dt-received= dt-revised= dt-accepted= dt-pub-year=1971 dt-pub=19711230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Changes in Rations of High Molecuar Fatty Acid Composition, Constituting Hepatic Lipids in Irradiated Animals Part 2. Differences in the metabolism palmitic acid and linoleic acid in irradiated animals kn-title=放射線照射動物に於る肝脂質構成高級脂肪酸比の変動について 第2編 放射線照射動物に於るパルミチン酸とリノール酸の代謝変化の相違について en-subtitle= kn-subtitle= en-abstract= kn-abstract=After giving whole-body irradiation of 600R, albumin complexed-palmitic acid-1-(14)C or linoleic acid-(14)C were used to mice, and we studied differences in changes of metabolism in these irradiated animals. For this study we messured amounts of (14)CO(2) exhaled, specific activity of liver lipids, and activities of individual fatty acid fractions with lapse of time, and obtained the following results. 1) It was found that the incorporation of palmitic acid-1-(14)C into (14)CO(2) was increased about 150% in the irradiated group as compared with that in controls. In contrast, that of linoleic acid-1-(14)C was decreased by about 50% as compared with controls. 2) The incorporation of palmitic acid-1-(14)C into liver lipids was considerable in the early stage after the the irradiation, but it decreased rapidly and became less than that of controls within a short period of time. The uptake of linoleic acid-1-(14)C into the liver of inadiated qroup was found to have been decreased. 3) In the irradiated groups, data revealed an inhibitory effect on unsaturation and chain elongation of both palmitic acid and linoleic acid. en-copyright= kn-copyright= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学ヘ室 END start-ver=1.4 cd-journal=joma no-vol=83 cd-vols= no-issue=11-12 article-no= start-page=537 end-page=544 dt-received= dt-revised= dt-accepted= dt-pub-year=1971 dt-pub=19711230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on Changes in Rations of High Molecuar Fatty Acid Composition, Constituting Hepatic Lipids in Irradiated Animals Part 1. Changes in fatty acid biosynthesis in irradiated animals kn-title=放射線照射動物に於る肝脂質構成高級脂肪酸比の変動に関する一考察 第1編 放射線照射動物に於る脂肪酸合成の変化について en-subtitle= kn-subtitle= en-abstract= kn-abstract=In our experiments of fatty acid biosynthesis in vivo with mice given whole-body irradiation of 600R using acetate-1-(14)C, we studied the amounts of (14)CO(2) exhaled, specific activity of total lipids, and activities of each fatty acid fraction of the liver, and obtained the results as follows. 1) It has been found that at early stage after irradiation the majority of acetate is utilized in oxidation and the part used in the biosynthesis is less, in the irradiated animals than in controls. 2) In these irradiated animals the biosynthesis of palmitoleic acid and stearic acid is relatively inhibited. en-copyright= kn-copyright= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学ヘ室 END start-ver=1.4 cd-journal=joma no-vol=83 cd-vols= no-issue=11-12 article-no= start-page=531 end-page=536 dt-received= dt-revised= dt-accepted= dt-pub-year=1971 dt-pub=19711230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A Case with Myxoma Accompanying pericardial Cyst kn-title=心膜憩室に合併せる粘液腫の一症例について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Disease exhibiting an abnormal tumorous shadow on the pericardium in x-ray picture is rare, and that with pericardial cyst is still more scarce. Having encountered a case, suspected of pericardial cyst, which on surgical operation proved to be of pericardial diveaticle accompanied by myxoma, we presented details of our findings on this very rare case. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=2 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=3 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=4 ORCID= en-aut-name=WatanabeSetsuo en-aut-sei=Watanabe en-aut-mei=Setsuo kn-aut-name=渡辺節生 kn-aut-sei=渡辺 kn-aut-mei=節生 aut-affil-num=5 ORCID= en-aut-name=EbaraKazuhiko en-aut-sei=Ebara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学ヘ室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学ヘ室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学ヘ室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学ヘ室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学ヘ室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学ヘ室 END start-ver=1.4 cd-journal=joma no-vol=83 cd-vols= no-issue=11-12 article-no= start-page=523 end-page=529 dt-received= dt-revised= dt-accepted= dt-pub-year=1971 dt-pub=19711230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Some Consideration on Contracture of the Pyloric Antrum kn-title=胃前庭部攣縮に対する考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In our routine X-ray examinations of the stomach we do no longer encounter much difficulty in the diagnosis of the case. By virtue of a marked improvement of the X-ray instruments as well as by a great advance in techniques of the diagnosis we now can use endoscope, fibrinoscope, cytological examinations among others that our diagnosis is betting more and more accurate, as revealed by many reports. Nonetheless, the difficulty we encounter in our X-ray diagnosis is in those cases with contracture or deformation in the pyloric antrum. Of course, in the cases with malignant pathological changes or ulcers, we face relatively less problems, but in those cases with various pathological changes on the mucous coat such as an irregular relief, a partial hypertropy or lacking in any definite finding, we find it difficult to decide whether such changes have been elicited by gastritis or other causes. We discussed about how we might handle when we meet such cases with contracture of the pyloric antrum. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=2 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=3 ORCID= en-aut-name=WatanabeSetsuo en-aut-sei=Watanabe en-aut-mei=Setsuo kn-aut-name=渡辺節生 kn-aut-sei=渡辺 kn-aut-mei=節生 aut-affil-num=4 ORCID= en-aut-name=IidaSosuke en-aut-sei=Iida en-aut-mei=Sosuke kn-aut-name=飯田荘介 kn-aut-sei=飯田 kn-aut-mei=荘介 aut-affil-num=5 ORCID= en-aut-name=FujiwaraKanji en-aut-sei=Fujiwara en-aut-mei=Kanji kn-aut-name=藤原幹治 kn-aut-sei=藤原 kn-aut-mei=幹治 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=83 cd-vols= no-issue=9-10 article-no= start-page=435 end-page=448 dt-received= dt-revised= dt-accepted= dt-pub-year=1971 dt-pub=19711030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on some indicators to measure effects of irradiation on L-strain cells in tissue culture kn-title=組織培養法による放射線障害の測定指標に関する研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=There are very few studies of the indicators which measure the effects of irradiation, even though it is very important in assessing the mechanism of radiation injuries and evaluating the effect of chemical protection against radiation hazard. Previous studies used either in vivo survival or in vitro cell counts to measure radiation effects. The study describes the use of cell volume, intracellar DNA, and cell counts as indicators of the effects of irradiation on cells in tissue culture, and demonstrated the effects of AET (S2-Amino-ethylisothiuronium bromide) as chemical protection against radiation hazards as measured by these three indicators. The results are as follows: 1) Combined use of the three indicators demonstrated that the effect of radiation on L-strain cell in tissue culture resulted from extension of the cell's mitotic phase and inhibition of cell division. 2) A positive correlation in the indicators was found with high dose irradiation (800r) of cells in tissue culture, but there was no correlation noted at lower test doses (200r and 400r). This finding demonstrated that it is necessary to study irradiation effects using these indicators in combination, especially at low dose exposures. 3) The study demonstrated that AET inhibited growth of irradiated L-strain cells and furthermore promoted cell bivision in tissue culture, thus showing the capacity for AET to tissue cells against irradiation. 4) Use of cell growth indicators such as cell volume, intracellular DNA, and cell counts, in combination, seems superior to previous methods of cell studies related to irradiation effects. en-copyright= kn-copyright= en-aut-name=NakataniTohru en-aut-sei=Nakatani en-aut-mei=Tohru kn-aut-name=中谷亨 kn-aut-sei=中谷 kn-aut-mei=亨 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡大医学部衛生学教室 END start-ver=1.4 cd-journal=joma no-vol=85 cd-vols= no-issue=11-12 article-no= start-page=593 end-page=599 dt-received= dt-revised= dt-accepted= dt-pub-year=1973 dt-pub=19731230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Osteopetrosis A case presentation kn-title=大理石骨病の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Osteopetrosis (Albers-Schonberg's disease, marble bones) is a rare disease characterized by generalized increased density of the skeleton. A case showing typical roentgenological findings of the disease is presented and following a brief review of the literature, the roentgenographic characteristics are discussed. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=2 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=3 ORCID= en-aut-name=TakagiHisao en-aut-sei=Takagi en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=4 ORCID= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=5 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=6 ORCID= en-aut-name=OkudaKozo en-aut-sei=Okuda en-aut-mei=Kozo kn-aut-name=奥田浩三 kn-aut-sei=奥田 kn-aut-mei=浩三 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=弘仁会共立病院(愛媛県) END start-ver=1.4 cd-journal=joma no-vol=85 cd-vols= no-issue=7-8 article-no= start-page=323 end-page=330 dt-received= dt-revised= dt-accepted= dt-pub-year=1973 dt-pub=19730830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Two Cases of Crohn's Disease kn-title=Crohn病の2症例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We encountered a 24-year old female with a swelling and severe pain in the hypogastric region as her main complaints and another 32-year old male with hypogastric pain persisting for several years as main complaint. On the x-ray examinations of the gastrointestinal tract of these two cases, both of them were suspected of Crohns disease, and they were subjected to surgical operation. As to a result of pathohistological examinations they were definitively diagnosed as case of Crohns disease. As to the definition of Crohns disease opinions differ even today, but we presented of our findings on these two cases as well as our review on the x-ray pictures on Crohns disease available in the literature. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=2 ORCID= en-aut-name=KawaseEtsuro en-aut-sei=Kawase en-aut-mei=Etsuro kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=3 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=4 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=5 ORCID= en-aut-name=TakagiHisao en-aut-sei=Takagi en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=6 ORCID= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=7 ORCID= en-aut-name=KatsumataNaomi en-aut-sei=Katsumata en-aut-mei=Naomi kn-aut-name=勝俣直躬 kn-aut-sei=勝俣 kn-aut-mei=直躬 aut-affil-num=8 ORCID= en-aut-name=IidaSosuke en-aut-sei=Iida en-aut-mei=Sosuke kn-aut-name=飯田荘介 kn-aut-sei=飯田 kn-aut-mei=荘介 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=88 cd-vols= no-issue=3-4 article-no= start-page=197 end-page=207 dt-received= dt-revised= dt-accepted= dt-pub-year=1976 dt-pub=19760430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the lipid peroxidation in mitochondria of x-ray whole-body irradiated rat liver U. Changes of fatty acid composition and ferrous ion-induced peroxidation of mitochondrial lipid after whole-body irradiation kn-title=X線全身照射のラット肝ミトコンドリアにおける脂質過酸化反応に関する研究 第二編 脂質ならびに脂肪酸組成の変動と抽出脂質のFe(++)誘導脂質過酸化反応について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Ferrous ion-induced lipid peroxidation of the mitochondria isolated from rat liver on the 3rd day after x-ray whole-body irradiation at 650R showed shortening of the lag of induction period and more acceleration of the activity than those of normal mitochondria (Part 1). Further investigations were made on the mitochondria on the 3rd day after irradiation at 650R in regard to fatty acid compositions and Fe(++) -induced peroxidation of total or fractionated mitochondrial lipids. The results are represented as follows. 1) Fatty acid composition of the mitochondria after lipid peroxidation showed the decrease of polyenoic acids (C-20:4, C-22:6), suggesting the polyenoic acids are substrate of the reaction. 2) Changes of fatty acid composition of mitochondria after whole-body irradiation at 650R were shown decreasing of unsaturated fatty acid due to the decrement of C-18:1 and C-18:2, but the component of polyenoic acid increased relatively. These changes are transient, reaching a maximum on the 3rd day after irradiation, and this tendency is parallel to that of lipid peroxidation activity of the mitochondria whole-body irradiated. 3) No difference of the rate of peroxidation observed between total lipids extracted from normal and from whole-body irradiated mitochondria, and the lag of induction period was not seen in both reactions. 4) Peroxidation of the total lipid was seen markedly in the phospholipid fraction and slightly in the simple lipid fractions. Effect of whole-body irradiation on the peroxidation activities of the phospholipid was not observed significantly, despite of the difference seen in their fatty acid compositions. 5) Peroxidation of subfractionated phospholipid by a thin-layer chromatography showed marked activity in the fractions of lecithin and aminophosphatide containing large amounts of C-20:4 and C-22:6: Recovery of the activity of the subfractions increased markedly comparing to the total phospholipid, and effect of whole-body irradiation appeared significantly in these subfractions. However, relationship between activities of the peroxidation and fatty acid compositions of the subfractions cannot seen. It is suggested the mutual interaction of phopholipid subfractions on the peroxidation to decrease the activity, and some of lipid became more sensitive to peroxidation by irradiation. 6) Relative amount of phospholipid to total lipid increased in whole-body irradiated samples. 7) From these findings, it was discussed that the acceleration of Fe(++) -induced lipid peroxidation in mitochondrial level is due to the change of fatty acid composition and association of lipid in the membrane. en-copyright= kn-copyright= en-aut-name=WakabayashiHiroshi en-aut-sei=Wakabayashi en-aut-mei=Hiroshi kn-aut-name=若林弘 kn-aut-sei=若林 kn-aut-mei=弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=88 cd-vols= no-issue=3-4 article-no= start-page=185 end-page=196 dt-received= dt-revised= dt-accepted= dt-pub-year=1976 dt-pub=1976 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the lipid peroxidation in mitochondria of x-ray whole body irradiated rat liver T. Change of Fe(++) -induced lipid peroxidation of mitochondria isolated from rat liver after irradiation kn-title=X線全身照射のラット肝ミトコンドリアにおける脂質過酸化反応に関する研究第一編 X線全身照射にともなうラット肝ミトコンドリアのFe++誘導脂質過酸化反応の変動について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Lipid peroxidation of biomembrane is important in terms of the mechanism which are involved in the regulation and deterioration of their structure. To elucidate the behavior of lipid peroxidation in biomembrane after x-ray irradiation, the lipid peroxidation induced by Fe(++) in mitochondria after whole body irradiation was investigated, and the results are presented as follows. (1) Mitochondria were isolated from rat liver with the passage of day after 650 R irradiation, and the change of Fe(++) -induced lipid peroxidation was estimated by the TBA assay. Rates of the lipid peroxidation increased after irradiation and reached a maximum 3 days after irradiation, which was shown by shortening the lag of induction period and by the increase of TBA value per mg of protein. The increment of the activity was temporary and then the activity returned. (2) On the 3rd day after irradiation, the rat was more light in weight, and the wet weight of liver per body weight and the yield of mitochondria per tissue equivalent were increased transitorily in parallel with the change of the TBA value. (3) The shortening lag period and the high rate of TBA value depend on the dose of whole body irradiation. (4) The activity of oxidative phosphorylation of the mitochondria on the 3rd day after irradiation did not differ as compared with that of normal mitochondria. (5) These results suggest that the change of Fe(++) -induced lipid peroxidation of mitochondria after whole body irradiation is due to the irradiation. The factors in regulating the rate of lipid peroxidation were discussed. en-copyright= kn-copyright= en-aut-name=WakabayashiHiroshi en-aut-sei=Wakabayashi en-aut-mei=Hiroshi kn-aut-name=若林弘 kn-aut-sei=若林 kn-aut-mei=弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=88 cd-vols= no-issue=3-4 article-no= start-page=163 end-page=166 dt-received= dt-revised= dt-accepted= dt-pub-year=1976 dt-pub=19760430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title= kn-title=血清脂質過酸化物の生成に及ぼす放射線照射の影響 第二編 臨床例(子宮頚癌症例)についての検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HaisaYoshio en-aut-sei=Haisa en-aut-mei=Yoshio kn-aut-name=羽井佐芳雄 kn-aut-sei=羽井佐 kn-aut-mei=芳雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=85 cd-vols= no-issue=3-4 article-no= start-page=145 end-page=150 dt-received= dt-revised= dt-accepted= dt-pub-year=1973 dt-pub=19730430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of Irradiation On Lipid Peroxidation in Rat Organs.Part V. Effects of irradiation on lipid peroxide formation and administration of radiation-protective agents (in vivo) in rat organs kn-title=ラット臓器の脂質過酸化反応におよぼす放射線照射の影響 第3編 放射線照射ラツト各臓器の脂質過酸化物形成能に及ぼす放射線防護物質投与(in vivo)の影響について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Effects of tathione and cepharanthin, the radiation-protective agents, on the lipid peroxidation in rat organs were studied, and obtained the results as follows. (1) The acceleration of lipid peroxide formation induced by X-irradiation can be inhibited by the administration of tathione prior to the irradiation and by the dose administered. Such an inhibitory effect is especially marked in the liver, and as reported in Part T and Part U, in view of correlations among X-irradiation effect, lipid peroxidation and fatty acid composition in the liver, it seems that glutathione in vivo is somehow involved in the acceleration of lipid peroxidation. (2) The increase of lipid content observable in the liver of X-irradiated animal could not be observed in the animals administered with tathione. (3) Cepharanthin showed not any relation to the lipid peroxidation. en-copyright= kn-copyright= en-aut-name=WatanabeSetsuo en-aut-sei=Watanabe en-aut-mei=Setsuo kn-aut-name=渡辺節生 kn-aut-sei=渡辺 kn-aut-mei=節生 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=85 cd-vols= no-issue=3-4 article-no= start-page=137 end-page=143 dt-received= dt-revised= dt-accepted= dt-pub-year=1973 dt-pub=19730430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of Irradiation on Lipid Peroxidation In Rat Organs. Part U. Changes in lipid peroxidation and ratio of fatty acid composition in rat organs after irradiation kn-title=ラット臓器の脂質過酸化反応におよぼす放射線照射の影響 第2編 放射線照射ラット臓器における脂質過酸化反応と脂肪酸構成比の変動について en-subtitle= kn-subtitle= en-abstract= kn-abstract=With four groups of rats, normal, irradiated, fasting, and irradiated-then-fasting rats (dose of X-ray, 650R), 48 hours afterwards, liver, heart, spleen and kidney were examined separately as to changes in the acceleration of lipid peroxidation and fatty acids due to irradiation were examined and obtained the results as follows. (1) The lipid peroxidation in each organ was accelerated after irradiation when compared to that in the organs of normal group. In the fasting group the acceleration of lipid peroxidation was observed, but the acceleration in the irradiated group was far more marked, indicating clearly the effect of irradiation. (2) As to changes in the ratio of fatty acid composition in every organ of the irradiated group there were observed an increase in the ratio of high unsaturated fatty acids and a decrease in the ratio of saturated fatty acids as compared with the respective values in normal group. Among organs there could be recognized no uniform change in the fasting group and the irradiated-then-fasting group. These results indicate that the fasting affects the ratio of fatty acid composition, especially marked was change in triglyceride fraction. (3) The lipid content in the liver tends to increase after irradiation, and there is also observed an incrase in the ratio of lipids to phospholipids. (4) The arachidonic acid of phospholipid what is considered to be substrate of lipid peroxidation is increased in the irradiated group, suggesting its relation to the acceleration of lipid peroxidation accompanying irradiation, and actually, the arachidonic acid ratio of phospholipid is markedly decreased after the incubation of lipid peroxidation reaction in the presence of Fe(++), indicating that this substance can play the role of substrate. en-copyright= kn-copyright= en-aut-name=WatanabeSetsuo en-aut-sei=Watanabe en-aut-mei=Setsuo kn-aut-name=渡辺節生 kn-aut-sei=渡辺 kn-aut-mei=節生 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=85 cd-vols= no-issue=3-4 article-no= start-page=129 end-page=136 dt-received= dt-revised= dt-accepted= dt-pub-year=1973 dt-pub=19730430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effects of Irradiation on Lipid Peroxidation in Rat Organs.Part T. Effects of whole body irradiation on lipid peroxide formation in rat organs. kn-title=ラット臓器の脂質過酸化反応におよぼす放射線照射の影響 第1編 放射線全身照射ラット臓器の脂質過酸化物形成能について en-subtitle= kn-subtitle= en-abstract= kn-abstract=After the whole body X-irradiation (650R) of rats, the lipid peroxide formation of various organs were estimated by the TBA reaction, and the results are presented as follows: (1) In TBA reaction tests on the lipid peroxidation in the liver, heart, spleen and kidney with homogenates being incubated, the TBA value were slightly high with endogenous homogenates, but on the addition of Fe(++) the reaction was further accelerated markedly. With liver and kidney that showed a high reaction on addition of Fe(++), the reaction was similarly accelerated on addition of ascorbic acid, but with heart and spleen the reaction at initial stage did not show any significant difference from that of the group without any addition. (2) In every organ from the irradiated animal the activity of lipid peroxide formation was greater than that in organs from non-irradiated control animals. (3) TBA value in the group added with Fe(++) were higher than those in the group without any addition, suggesting that X-irradiation greatly the lipid peroxidation in organs. (4) Change in the acceleration of lipid peroxidation accompanying the irradiation appears as a shortening of reaction-induction time. (5) Radioactivity-dose dependent change can be observed only in the liver, and the time-lapse change after irradiation can also observed only in the liver. (6) These results suggest that the lipid peroxidation following the whole body X-irradiation shows a significant change primarily in the liver. en-copyright= kn-copyright= en-aut-name=WatanabeSetsuo en-aut-sei=Watanabe en-aut-mei=Setsuo kn-aut-name=渡辺節生 kn-aut-sei=渡辺 kn-aut-mei=節生 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=9-10 article-no= start-page=1297 end-page=1308 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19781030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Participation of superoxide generating system, superoxide dismutase and vitamin E in the radiation hazards kn-title=放射線障害におけるスーパーオキサイド生成系(O(2))とスーパーオキサイド・ディスムターゼ(SOD)及びビタミンEの関与に対する考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=In relation to the mechanism by which hemolysis was induced in radiated human erythrocytes in vitro, several inducements of membrane lipid peroxidation and protective effects of V.E and SOD were investigated. Results obtained were as follows: (1) K(+)-release from erythrocytes was accelerated by radiation prior to hemolysis. These accelerated hemolysis and K(+)-release were protected remarkably by V.E and evidently by SOD. (2) Mitochondrial Fe(2+) induced and Fe(3+)-O(2) generating system -ADP induced lipid peroxidation, and microsomal O(2) generating system -induced lipid peroxidation were also protected by V.E and SOD. (3) Radiation of X-ray or (60)Co γ-ray accelerated lipid peroxidation of liver homogenate, microsome and liposome. Some of these accelerated lipid peroxidations were protected effectively by V.E and SOD. These results suggest that O(2) and/or OH. generation by radiation induces of membrane lipid peroxidation, which leads deterioration of membrane resulting in the change of ion permeability and then hemolysis. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=2 ORCID= en-aut-name=IidaSosuke en-aut-sei=Iida en-aut-mei=Sosuke kn-aut-name=飯田荘介 kn-aut-sei=飯田 kn-aut-mei=荘介 aut-affil-num=3 ORCID= en-aut-name=UtsumiKozo en-aut-sei=Utsumi en-aut-mei=Kozo kn-aut-name=内海耕慥 kn-aut-sei=内海 kn-aut-mei=耕慥 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部癌源研究所生化学部門 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=9-10 article-no= start-page=1157 end-page=1163 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19781030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Diagnosis of heart disease using by RI angio cardiography Part V. Cases of left to right shunts kn-title=RI Angiocardiographyによる心疾患の診断 第3編 左-右シャント症例について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Count ratio (C(2)/C(1)) technique for detection of left to right shunts by radionuclide was performed. Count ratio technique of ASD cases accurately detected shunts and could reliably separate from normals, but there were a few false positive in patients with ventricle septal defect. There was no correlation between C(2)/C(1) ratio and oximetry. Postoperatively, C(2)/C(1) ratios of ASD cases were resumed to normal or close to normal but some cases of VSD were not returned to normal. en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=1 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=2 ORCID= en-aut-name=KawaseEtsuo en-aut-sei=Kawase en-aut-mei=Etsuo kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=3 ORCID= en-aut-name=TakakiHisao en-aut-sei=Takaki en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=4 ORCID= en-aut-name=MizukawaKiichiro en-aut-sei=Mizukawa en-aut-mei=Kiichiro kn-aut-name=水川帰一郎 kn-aut-sei=水川 kn-aut-mei=帰一郎 aut-affil-num=5 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=6 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=7 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大孝医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大孝医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=9-10 article-no= start-page=1145 end-page=1149 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19781030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Diagnosis of heart disease using by RI angiocardiography Part U. Mitral valve disease kn-title=RI angio-cordiographyによる心疾患の診断 第2編 僧帽弁疾患症例を中心として en-subtitle= kn-subtitle= en-abstract=This report represents an extension of our use of a Scintillation (Anger) camera with computer processing (Toshiba DAP 5000-2) of data for evaluation of mitral valve disease (11 cases). For these studies we have administered 10 mCi of (99m)Tc intravenously and have followed its passage through the heart and lung using techniques for data acquisition: a 35 mm camera, a video tape system for data storage and replay for computer analysis using a DAP 5000-2. RI dilution curves recorded on the right ventricle, the left lung and the left ventricle were analyzed to obtain following parameters, namely interventricular peak to peak time, C(2)/C(1) ratio of each dilution curves. These data showed following: 1) Interventricular peak to peak time normal group (12 cases): 6.40 ± 1.18 seconds mitral valve disease (11 cases): 11.34 ± 3.69 seconds 2) a) C(2)/C(1) ratio of the right ventricle normal group: 0.45 ± 0.08 seconds mitral valve disease: 0.58 ± 0.17 seconds b) C(2)/C(1) ratio of the left ventricle normal group: 0.38 ± 0.09 seconds mitral valve disease: 0.49 ± 0.11 seconds c) C(2)/C(1) ratio of the left lung normal group: 0.45 ± 0.08 seconds mitral valve disease: 0.50 ± 0.12 seconds kn-abstract=心疾患を有する患者では,その循環動態は種々の因子により容易に変化するものであり,一回の検査のみで決して正確にその患者の動態を表わしているとはいいがたい.この点コンピューターを用いたRI angio-cardiography(以下RCGと略す)は被曝線量も少く,生理的状態を損うことなく繰返し検査を行うことが出来る非観血的方法であり,心疾患者の術前術後の変化,治療経過観察に極めて有用である.従って,僧帽弁疾患におけるRCGによる右室,左室peak to peak time C(2)/C(1)比の解折は,上述の点後於て重要な臨床情報を提供すると考えられる.今回は僧帽弁疾患を中心としてこれらの点について若干の検討を試みた. en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=1 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=2 ORCID= en-aut-name=KawaseEtsuo en-aut-sei=Kawase en-aut-mei=Etsuo kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=3 ORCID= en-aut-name=TakakiHisao en-aut-sei=Takaki en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=4 ORCID= en-aut-name=MizukawaKiichiro en-aut-sei=Mizukawa en-aut-mei=Kiichiro kn-aut-name=水川帰一郎 kn-aut-sei=水川 kn-aut-mei=帰一郎 aut-affil-num=5 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=6 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=7 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=8 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=87 cd-vols= no-issue=7-8 article-no= start-page=637 end-page=644 dt-received= dt-revised= dt-accepted= dt-pub-year=1975 dt-pub=19750831 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effect of Irradiation on Lipid Peroxidation in SerumPart 1. Changes in lipid peroxidation in rabbit serum after irradiation kn-title=血清脂質過酸化物の生成に及ぼす放射線照射の影響 その1 基礎的検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=For the purpose to elucidate the formation and the mechanism of lipid peroxidation products in the serum following irradiation, rabbits were irradiated once withe 1000R over the whole body, and serum lipid proxidation products as well as proxidation products in each lipid fractions were measured as TBA level. In addition, a study was made on the correlation between the peroxidation product and the change of fatty acids, and the following results were obtained. 1) The whole lipid content of serum: The whole lipid content was found to have increased about 2.6 times that before the irradiation by 24 post-irradiation hours, and even after the lapse of 48 hours such a tendency persisted. 2) Serum whole TBA level: By 24 post-irradiation hours the whole TBA level increased markedly up to about 6.5-fold that before the irradiation. 3) Lipid content of fraction: Except for cholesterol, every lipid fractions are found to have increased after irradiation. Especially marked is the increase of triglyceride. 4) TBA level of fractionated lipid: There is seen a marked increase of cholesterol ester, which proctically occupied entire serum TBA value. Next marked was the increase of phospholipid, and quantitatively it was classified that the increases seen in triglyceride and free fatty acids are not concerned with the rise in the free fatty acid content and TBA level. 5) Serum lipid contents and TBA level infasting: By taking the level of serum lipid 24 hours after the start of fasting as one, the serum lipid levels were studied at 48 and 72 hours after the start of fasting, and it was found that both serum lipid and TBA levels rose only very slightly. 6) Changes of fatty acids: The relative ratio of palmitic acid of the whole fatty acids increased after irradiation, and the ratio of linolic acid and linolenic acid was decreased by irradiation while by 48 hours the relative ratio of linolic acid was decreased to about 1/5 that before irradiation, and the relative ratio of linolenic acid was markedly decreased to about 1/35. en-copyright= kn-copyright= en-aut-name=HaisaYoshio en-aut-sei=Haisa en-aut-mei=Yoshio kn-aut-name=羽井佐芳雄 kn-aut-sei=羽井佐 kn-aut-mei=芳雄 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=7-8 article-no= start-page=993 end-page=998 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=197808 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Diagnosis of heart disease using by RI angiocardiography Part I. Normal subjects kn-title=RI angio-cardiographyによる心疾患の診断 第一編 正常例の検討 en-subtitle= kn-subtitle= en-abstract= kn-abstract=This study is to show applicability of RCG and to determine criteria for its use of normals. Instrumentation for data processing was DAP 500-2(Toshiba, Ltd, Tokyo Japan) RI dilution curves recorded an the right ventricle, the left lung, the left ventricle of 12 normal subjects were analyzed to obtain following parameters, namely interventricular peak to peak time and C(2)/C(1) ratio. 1) intraventricular peak to peak time average: 6.40 ± 1.18 seconds (4.80~8.64) 2) C(2)/C(1) ratio of right ventricle average: 0.45 ± 0.08 seconds (0.30~0.59) 3) C(2)/C(1) ratio of left ventricle average: 0.38 ± 0.09 seconds (0.22 ± 0.51) 4) C(2)/C(1) ratio of left lung average: 0.45 ± 0.08 seconds (0.30~0.55) en-copyright= kn-copyright= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=1 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=2 ORCID= en-aut-name=KawaseEtsuo en-aut-sei=Kawase en-aut-mei=Etsuo kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=3 ORCID= en-aut-name=TakakiHisao en-aut-sei=Takaki en-aut-mei=Hisao kn-aut-name=高木寿生 kn-aut-sei=高木 kn-aut-mei=寿生 aut-affil-num=4 ORCID= en-aut-name=MizukawaKiichiro en-aut-sei=Mizukawa en-aut-mei=Kiichiro kn-aut-name=水川帰一郎 kn-aut-sei=水川 kn-aut-mei=帰一郎 aut-affil-num=5 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=6 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=7 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=8 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=9 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=5-6 article-no= start-page=545 end-page=550 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19780630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experiences in the use of ACTA scanner (type 0100) Part 2. Consideration on the use of ACTA scanner kn-title=ACTAスキャナー0100型の使用経験 第2報 CT装置の使用に対する考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We have previously reported an outline of the ACTA scanner and its usefulness. In this report, we intend to present some aspects of the apparatus itself needing improvement and also offer our opinion on some points to be borne in mind on the actual use of the scanner. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=2 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=4 ORCID= en-aut-name=KawaseEtuo en-aut-sei=Kawase en-aut-mei=Etuo kn-aut-name=川瀬悦郎 kn-aut-sei=川瀬 kn-aut-mei=悦郎 aut-affil-num=5 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=6 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=7 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=8 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=5-6 article-no= start-page=537 end-page=543 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19780630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Experiences in the use of ACTA scanner (type 0100) Part 1. Consideration on CT scanner kn-title=ACTAスキャナー0100型の使用経験 第1報 CT装置に対する考察 en-subtitle= kn-subtitle= en-abstract= kn-abstract=It is only a little over two odd years since computer tomography (CT) has come to be used in Japan. However, during this short period of time great interest in the CT apparatus has been aroused. As we have had the opportunity to use the ACTA scanner (type 0100) set in June, 1976 at the hospital affiliated to Okayama University, we describe here our experiences with it and introduce an outline of the CT apparatus as well as its usefulness. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=2 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=4 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=5 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=6 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=89 cd-vols= no-issue=9-10 article-no= start-page=1295 end-page=1305 dt-received= dt-revised= dt-accepted= dt-pub-year=1977 dt-pub=19771030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effect of X-irradiation in rats bearing Walker-256-carcinosarcoma and normal rats Part I. Changes in seromucoid values in tumor-bearing and normal rats after X-irradiation kn-title=Walker-256-carcinosarcoma移植ラット及び健康ラットにおよぼす放射線照射の影響 第1編 Walker-256-carcinosarcoma移植ラットへの放射線照射によるSeromucoid値及び放射線照射ラットのSeromucoid値の変動について en-subtitle= kn-subtitle= en-abstract= kn-abstract=In rats given implants of Walker tumor a sizeable increase in tumor mass has been shown to precede significant increases in the seromucoid values. Early irradiation to the tumor has prolonged the survival days, and then seromucoid values have remained within the normal limits. After the occurrence of metastatic growth, irradiation to the primary tumor has repressed the tumor growth but the seromucoid has increased significantly. If distant metastasis has occurred, the seromucoid values increase significantly. Therefore the usefulness of the seromucoid value in assessing the occurrence of metastatic growth is shown. The seromucoid values in rats given 300 rad partial body (the right hind leg) irradiation daily for 20 days have been within the normal limits. However, the seromucoid values in rats given 1,000 rad whole body irradiation at a time have gradually increased up to the 3rd day, and markedly increased in the 5th day after irradiation. The seromucoid values on the 5th day after irradiation were about 6.4 times as much as those of normal rats. en-copyright= kn-copyright= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=1-2 article-no= start-page=195 end-page=208 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19780228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Clinical observation on serum seromucoid in patients with malignant neoplasm -Relationship between serum seromucoid values in patients with cancer of the lung or cervix and with treatment for cancer kn-title=悪性腫瘍患者における血清Seromucoidの臨床的観察―原発性肺癌及び子宮頸癌患者の血清Seromucoid値及び治療との関係について en-subtitle= kn-subtitle= en-abstract= kn-abstract=Serum seromucoid values were measured in 30 controls, 21 patients with cancer of the lung and 30 patients with cancer of the cervix. The following results were obtained. 1) The values of serum seromucoid in patients with cancer of the lung were related to the severity of the clinical lesion. But in the cases (66.7%) with localized lesion the seromucoid values were unchanged from normal, so in these cases the measurement of serum seromucoid values is little useful as a diagnostic tool. On the other hand, change of serum seromucoid values was almost reflected to the enlargement or reduction of carcinoma. Therefore, the measurement of serum seromucoid value may be a useful index of monitoring the effectiveness of its treatment and assessing the recurrence or relapse of carcinoma. Serum seromucoid was remarkably increased just before the death. 2) In patients with cancer of the cervix, the normal seromucoid value was over half of the number. Therefore, the measurement of serum seromucoid value may be little useful for the diagnosis of cancer of the cervix. Change of serum seromucoid values was reflected to the reduction or disappearance of carcinoma by its treatment, and is possibly reflected to the infiltration to the adjacent organs or the survival of carcinoma. 3) In patients with cancer of the lung or cervix, relationship between serum seromucoid value and blood sedimentation rate or α1-globulin content was more correlated in patients with cancer of the lung than in patients with cancer of the cervix. 4) In patients with cancer of the lung or cervix, the value of serum seromucoid was related to its clinical stage. Particularly, there was the significant rank correlation between primary tumor size and serum seromucoid value. If the occurrence of distant metastasis was in patients with cancer of the lung, these serum values showed a tendency to be higher than values of patients with no distant metastasis. 5) In patients with cancer of the lung, when the quotient of serum seromucoid (value after radiotherapy/before radiotherapy) is below 1.0 and its serum value shows abnormally high value just after radiotherapy, or when the quotient is above 1.0, the prognosis of the patients is as if poor. 6) In cases with cancer of the cervix with no complications of other disorders, when the quotient of serum seromucoid is below 1.0 and its serum value is abnormally high just after radiotherapy, or when the quotient is above 1.0, any optimism of the prognosis of the patients may not be warranted. en-copyright= kn-copyright= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=90 cd-vols= no-issue=1-2 article-no= start-page=59 end-page=68 dt-received= dt-revised= dt-accepted= dt-pub-year=1978 dt-pub=19780228 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effect of X-irradiation in rats bearing Walker-256-carcinosarcoma and normal rats -Changes in serum proteins- kn-title=Walker-256-carcinosarcoma移植ラット及び健康ラットにおよぼす放射線照射の影響 ―特に血清蛋白質への影響について― en-subtitle= kn-subtitle= en-abstract= kn-abstract=Serum protein fractions and total proteins were studied with bloods obtained form the rats exposed each to the partial-, whole-bodies and the transplanted tumors (Walker-256-carcinosarcoma transplanted in the right hind leg). The following results were obtained. 1. The electrophoretic variation induced in the sera of tumor-bearing rats (Group U), and the content of total proteins decreased. Early irradiation to the tumor part of rats less induced the variations of the electrophoretic pattern and the decrease of the amount of serum total proteins. When the distant metastasis appeared during irradiation treatment, the electrophoretic patterns and content of total proteins changed proportionally to the variation in sera of Group U. On the other hand, the γ-globulin fraction increased in the long-term survival rat. 2. The separation of the rat serum β-globulin into two peaks of β(1)-and β(2)-globulin was shown only in Group W (late irradiation to the right hind leg). This finding supposed that some factors involve in the sera of rats with transplanted primary tumor grown up to a fixed size and guessed the appearance of the distant metastasis during X-irradiation. 3. The percentages of the albumin and γ-globulin decreased slightly and those of the α(1)-, α(2)and β-globulin increased slightly in the rats with 300 rad partial-body (the right hind leg) X irradiation daily for 20 days. 4. The remarkable decrease of the albumin and γ-globulin, the increase of the α(1) and β-globulin, the marked increase of the α(2)-globulin and the decrease of serum total proteins were demonstrated for the sera of rats with 1,000 rad whole-body X-irradiation at a time. These phenomena seem to be related to the destructive and reticuloendothelial injury by the exposure. en-copyright= kn-copyright= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue=3 article-no= start-page=215 end-page=218 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20091201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Extremely high-quality radiation therapy kn-title=高精度放射線治療 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KatsuiKuniaki en-aut-sei=Katsui en-aut-mei=Kuniaki kn-aut-name=勝井邦彰 kn-aut-sei=勝井 kn-aut-mei=邦彰 aut-affil-num=1 ORCID= en-aut-name=TakemotoMitsuhiro en-aut-sei=Takemoto en-aut-mei=Mitsuhiro kn-aut-name=武本充広 kn-aut-sei=武本 kn-aut-mei=充広 aut-affil-num=2 ORCID= en-aut-name=KanazawaSusumu en-aut-sei=Kanazawa en-aut-mei=Susumu kn-aut-name=金澤右 kn-aut-sei=金澤 kn-aut-mei=右 aut-affil-num=3 ORCID= affil-num=1 en-affil= kn-affil=岡山大学病院 放射線科 affil-num=2 en-affil= kn-affil=岡山大学病院 放射線科 affil-num=3 en-affil= kn-affil=岡山大学病院 放射線科 END start-ver=1.4 cd-journal=joma no-vol=121 cd-vols= no-issue=3 article-no= start-page=173 end-page=175 dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20091201 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Relief of cancer pain in a non small cell lung cancer patient by a polyhedral approach kn-title=多角的アプローチにより癌性疼痛のコントロールを得ることができた非小細胞肺癌の一例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We report a case of cancer-related pain relieved by a polyhedral approach. A woman in her late 30s with advanced non small cell lung cancer suffered from back pain caused by the cancer invasion to a thoracic vertebra. She could not take a sufficient dose of opioid due to its adverse effects. A supplementary analgesic was not found to be effective. Palliative radiation was considered desirable, but she could not maintain a dorsal position for irradiation due to back pain. Continuous epidural anesthesia was then introduced. Epidural anesthesia allowed her to lie in a spine position for radiation therapy. After completion of radiation therapy, her back pain was relieved with a low dose of transdermal fentanyl without epidural anesthesia. en-copyright= kn-copyright= en-aut-name=IchiharaEiki en-aut-sei=Ichihara en-aut-mei=Eiki kn-aut-name=市原英基 kn-aut-sei=市原 kn-aut-mei=英基 aut-affil-num=1 ORCID= en-aut-name=MatsuokaJunji en-aut-sei=Matsuoka en-aut-mei=Junji kn-aut-name=松岡順治 kn-aut-sei=松岡 kn-aut-mei=順治 aut-affil-num=2 ORCID= en-aut-name=TakigawaNagio en-aut-sei=Takigawa en-aut-mei=Nagio kn-aut-name=瀧川奈義夫 kn-aut-sei=瀧川 kn-aut-mei=奈義夫 aut-affil-num=3 ORCID= en-aut-name=MatsuzakiTakashi en-aut-sei=Matsuzaki en-aut-mei=Takashi kn-aut-name=松崎孝 kn-aut-sei=松崎 kn-aut-mei=孝 aut-affil-num=4 ORCID= en-aut-name=KatsuiKuniaki en-aut-sei=Katsui en-aut-mei=Kuniaki kn-aut-name=勝井邦彰 kn-aut-sei=勝井 kn-aut-mei=邦彰 aut-affil-num=5 ORCID= en-aut-name=KiuraKatsuyuki en-aut-sei=Kiura en-aut-mei=Katsuyuki kn-aut-name=木浦勝行 kn-aut-sei=木浦 kn-aut-mei=勝行 aut-affil-num=6 ORCID= en-aut-name=TanimotoMitsune en-aut-sei=Tanimoto en-aut-mei=Mitsune kn-aut-name=谷本光音 kn-aut-sei=谷本 kn-aut-mei=光音 aut-affil-num=7 ORCID= affil-num=1 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 緩和医療学講座 affil-num=2 en-affil= kn-affil=岡山大学大学院医歯薬学総合研究科 緩和医療学講座 affil-num=3 en-affil= kn-affil=岡山大学病院 血液・腫瘍・呼吸器・アレルギー内科 affil-num=4 en-affil= kn-affil=岡山大学病院 麻酔科蘇生科 affil-num=5 en-affil= kn-affil=岡山大学病院 放射線科 affil-num=6 en-affil= kn-affil=岡山大学病院 血液・腫瘍・呼吸器・アレルギー内科 affil-num=7 en-affil= kn-affil=岡山大学病院 血液・腫瘍・呼吸器・アレルギー内科 en-keyword=癌性疼痛 (cancer-related pain) kn-keyword=癌性疼痛 (cancer-related pain) en-keyword=硬膜外ブロック (epidural anesthesia) kn-keyword=硬膜外ブロック (epidural anesthesia) en-keyword=放射線療法 (radiation therapy) kn-keyword=放射線療法 (radiation therapy) END start-ver=1.4 cd-journal=joma no-vol=89 cd-vols= no-issue=7-8 article-no= start-page=851 end-page=858 dt-received= dt-revised= dt-accepted= dt-pub-year=1977 dt-pub=19770830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Studies on the lipid of rat dental pulp I. Analyses of lipid component and fatty acid composition in rat incisor pulps before and after whole-body x-ray irradiation kn-title=歯髄の脂質に関する研究 I ラット切歯歯髄の脂質ならびに脂肪酸組成の解析と放射線全身照射による変動 en-subtitle= kn-subtitle= en-abstract=Lipids and fatty acids extracted from rat incisor pulps before and after whole-body x-ray irradiation at 1000R were qualitatively and quantitatively analysed by means of thin-layer and gas-liquid chromatography, and the results are as follows. 1) Ratio of the total lipid weight to protein weight was obtained 0.26 in normal rat dental pulps. The ratio in the irradiated group (3 days after irradiation) did not change. 2) In fatty acid composition of lipid of normal rat incisor pulps, palmitic, oleic, stearic, arachidonic, and linoleic acids were much in this order, and palmitic, stearic and oleic acids were major component accounted for over 78% of the total fatty acids. In that of the irradiated group, the decrease of oleic acid and the increase of arachidonic acid were observed comparing those of normal pulp lipid. 3) The major lipid of normal dental pulps composed of phospholipid, choresterol, triglyceride and choresterol ester, and phospholipid and choresterol accounted for about 45% and 30% of the total lipids, respectively. In the irradiated group, the decrease of choresterol and the increase of choresterol ester were represented. 4) In results of tentative identification by various color reaction on the thin-layer chromatograph, the major phospholipids of dental pulps were lecithin, phosphatidyl ethanolamine and phosphatidyl serine, which accounted for over 90% of the total phospholipids. It is significant that phosphatidyl serine in dental pulp is greater than in any other mammalian soft tissue so far studied. In the irradiated group, it was slightly observed the increment of lecithin and the decrement of phosphatidyl serine, but they are not predominant. kn-abstract=ラット切歯歯髄の脂質組成ならびに脂肪酸組成を解析するとともに,あわせてエックス線全身照射の各々の組成に及ぼす影響を研究し次の如き結果を得た.(1)切歯歯髄の総脂質含量は蛋白量相対比にして0.26の値を得た.エックス線全身照射群(1000R照射後3日目のもの)の歯髄も同様0.26の値を得,その差は得られなかった.(2)正常切歯歯髄の総脂質の脂肪酸組成において,パルミチン酸,オイレン酸,ステアリン酸,アラキドン酸,リノール酸の順に主成分として認められ,前三脂肪酸で78%以上を占めた.エックス線全身照射群においてはオレイン酸の減少,アラキドン酸の増加が認められた.口腔領域への部分照射(1000R)でも同様の傾向がみられた.(3)正常切歯歯髄の脂質構成としてリン脂質,コレステロール,トリグリセリド,コレステロールエステルが主成分として認められ,リン脂質は45 % ,コレステロールは30 % を占めた.エックス線全身照射群ではリン脂質,トリグリセリドの構成比に変動はみられなかったが,コレステロールの減少とコレステロールエステルの増加が認められた.(4)正常切歯歯髄リン脂質の構成を各種呈色反応で仮同定した結果,レシチン,ホスファチジルエタノールアミン,ホスファチジルセリンが主成分として90 % 以上を占めた.特にホスファチジルセリン含量が多いのが注目される.照射群ではレシチンの増加,ホスファチジルセリンの減少など若干の組成比に変動がみられたが,対照との差は有意とは言えなかった. en-copyright= kn-copyright= en-aut-name=HashimotoGonosuke en-aut-sei=Hashimoto en-aut-mei=Gonosuke kn-aut-name=橋本郷之助 kn-aut-sei=橋本 kn-aut-mei=郷之助 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部口腔外科学教室 END start-ver=1.4 cd-journal=joma no-vol=89 cd-vols= no-issue=7-8 article-no= start-page=749 end-page=756 dt-received= dt-revised= dt-accepted= dt-pub-year=1977 dt-pub=19770830 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Effect of biscoclaurin alkaloids of the biomembrane system and its action mechanisms Part I. Inhibitory effects of cepharanthine on the K(+)-release after the injury to cell membrane kn-title=生体膜系に対するビスコクラウリン型アルカロイドの作用とその作用機序に関する研究 第1報 細胞膜傷害によるK(+)遊出に対するセファランチンの阻止作用 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Concerining the physiological properties possessed by the cell membrane, recently an attention has been called on various problems such as the cell recognition mechanism to begin with, and the mutual relationships among the intercellular communication mechanism, as well as the metabolism adjustment of membrane binding enzymes, aside from the compartmentation of substances. Essentially the physico-chemical properties of the membrane of cancer cell and proliferating cells are important in relation to the treatment of cancer. And attempts are being made to change the cell metabolism by artificially altering the physicochemical properties of the cell membrane. Cepharanthine, one of the biscoclaurin alkaloids, is known from olden days to possess a thanatophidia hemolytic property, but this property seems to bring about the change in the physico-chemical properties of the cell membrane, and it is interesting in the point that this substance may have a membrane modifying property. For these reasons, during the investigation on the actions of alkaloids on the cell membrane many interesting phenomena have been elucidated. This report presents the results recently obtained about the changes in physico-chemical properties of biological membrane by the treatment with cepharanthine. The obtained results were as follows. 1. Cepharanthine inhibits K(+)-release from red blood cells when these cells are treated with snake venom, phospholipase A, lysolecithine, lead acetate and hexane. But the alkaloid does not inhibit K(+)-release induced by ionophores, surface active agents and HVJ. 2. Cepharanthine inhibits the hyperpolalization of membrane potential induced by lead acetate or hexane. 3. Similar inhibitory effect of cholesterol on K(+)-release from the cells by the treatment with lead acetate is observed. 4. From these results it is suggested that the inhibitory action of cepharanthine on K(+)-release from cells is due to the action of decrease in membrane fluidity. en-copyright= kn-copyright= en-aut-name=MiyaharaMasanobu en-aut-sei=Miyahara en-aut-mei=Masanobu kn-aut-name=宮原正信 kn-aut-sei=宮原 kn-aut-mei=正信 aut-affil-num=1 ORCID= en-aut-name=UtsumiKozo en-aut-sei=Utsumi en-aut-mei=Kozo kn-aut-name=内海耕慥 kn-aut-sei=内海 kn-aut-mei=耕慥 aut-affil-num=2 ORCID= en-aut-name=SagiyamaKatsumi en-aut-sei=Sagiyama en-aut-mei=Katsumi kn-aut-name=杉山勝三 kn-aut-sei=杉山 kn-aut-mei=勝三 aut-affil-num=3 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=4 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部第一病理学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部附属癌源研究施設生化学研究部門 affil-num=3 en-affil= kn-affil=岡山大学医学部薬理学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 END start-ver=1.4 cd-journal=joma no-vol=92 cd-vols= no-issue=9-10 article-no= start-page=1015 end-page=1024 dt-received= dt-revised= dt-accepted= dt-pub-year=1980 dt-pub=19801030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Alteration of mitochondrial functions by lipid peroxidation and inhibition by biscoclaurine alkaloid kn-title=脂質過酸化反応によるミトコンドリァ機能の変化とビスコクラウリン型アルカロイドによる阻害作用 en-subtitle= kn-subtitle= en-abstract= kn-abstract=During investigation of the changes in mitochondrial function accompanying lipid peroxidation, it was found that a biscoclaurine alkaroid protected their functional changes. The results obtained were as follows: 1) Fe(2+) induces lipid peroxidation of isolated mitochondria, resulting in deterioration of oxidative phosphorylation. 2) This deterioration relates to alteration in ion compartmentation of the mitochondrial membrane and an increase in latent ATPase activity. 3) This deterioration by Fe(2+) in ion compartmentation of mitochondrial membrane is strongly protected by a biscoclaurine alkaloid, cepharanthine. 4) Cepharanthine also inhibits the mitochondrial. lipid peroxidation induced by Fe(2+). 5) The protective effect of cepharanthine against deterioration in mitochondrial functions caused by Fe(2+) depends on its inhibitive action on lipid peroxidation as well as on its membrane stabilizing action. 6) Cepharanthine inhibits the lipid peroxidation of soybean lecithine liposomes by (60)Co-irradiation. 7) The action of cepharanthine described above is common to head to head type of biscoclaurin alkaloids which have diether bonds. en-copyright= kn-copyright= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=1 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=2 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=3 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=4 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=5 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=6 ORCID= en-aut-name=EzoeHiroshi en-aut-sei=Ezoe en-aut-mei=Hiroshi kn-aut-name=江添弘 kn-aut-sei=江添 kn-aut-mei=弘 aut-affil-num=7 ORCID= en-aut-name=TakedaYoshihiro en-aut-sei=Takeda en-aut-mei=Yoshihiro kn-aut-name=竹田芳弘 kn-aut-sei=竹田 kn-aut-mei=芳弘 aut-affil-num=8 ORCID= en-aut-name=MiyakeMasayoshi en-aut-sei=Miyake en-aut-mei=Masayoshi kn-aut-name=三宅正淑 kn-aut-sei=三宅 kn-aut-mei=正淑 aut-affil-num=9 ORCID= en-aut-name=HayashiHidehiro en-aut-sei=Hayashi en-aut-mei=Hidehiro kn-aut-name=林英博 kn-aut-sei=林 kn-aut-mei=英博 aut-affil-num=10 ORCID= en-aut-name=WakabayashiHisao en-aut-sei=Wakabayashi en-aut-mei=Hisao kn-aut-name=若林寿生 kn-aut-sei=若林 kn-aut-mei=寿生 aut-affil-num=11 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=12 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=13 ORCID= en-aut-name=ShiraishiNoriyuki en-aut-sei=Shiraishi en-aut-mei=Noriyuki kn-aut-name=白石則之 kn-aut-sei=白石 kn-aut-mei=則之 aut-affil-num=14 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部附属病院中央放射線部 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=13 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=14 en-affil= kn-affil=高知医科大学生物学教室 en-keyword=Lipid Peroxidation kn-keyword=Lipid Peroxidation en-keyword=Cepharanthine (Biscoclaurine Alkaloid) kn-keyword=Cepharanthine (Biscoclaurine Alkaloid) en-keyword=Mitochondrial Function kn-keyword=Mitochondrial Function END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=11-12 article-no= start-page=1591 end-page=1647 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19791230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Changes in teeth and mandibular vasculature following irradiation kn-title=放射線照射による下顎骨および歯の血管像変化に関する実験的研究 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Radiotherapy is an important mode of therapy for malignant tumors in the oro-mandibular area and the changes in vascularization which it causes are considered good indicators of both healing and the results of combined surgery and chemotherapy. The author studied the effects of radiotherapy on teeth and mandibular vascularization in 60 adult dogs. Cobalt irradiation of the lower right mandible was followed by intravascular injection of chloropercha to delineate the three-dimensional morphology of the changes. The histopathology, X-ray and macroscopic characteristics were also studied. The results were: (1) With 600 rad, fine capillaries around the roots of teeth increased. With 900-1,500 rad, the course of blood vessels became irregular. With 1,200 rad, there was a marked increase in capillary vessels which extended meanderingly. With 4,500 rad, the number of blood vessels was markedly decreased. Some vessels were irregular and unclear. (2) Vessels in the dental pulp showed mild meandering with 900 rad. They increased markedly with 1,200 rad and showed meandering. With 4,500 rad, the number of blood vessels decreased. (3) The histopathology showed that, with comparatively small amounts of irradiation, marked vascular disturbance accompanied by vascular dilation and edema had occurred. As the amount of irradiation increased, increased fibrosis of interstitial tissue, decreased numbers of blood vessels, and aseptic necrosis occurred, resulting finally in bone absorption and bone necrosis. (4) X-ray examination showed that mild constriction of the pulp cavity occurred. with 3,000 rad. This became marked with 4,500 rad and showed absorption. (5) Macroscopically, 900 rad caused mild edema in the cheek skin. With 3,000 rad, the oral cavity showed some ulceration. With 4,500 rad, necrosis of the gingiva occurred. (6) A certain correlation in the changes of blood vessels, X-ray findings, macroscopical, and pathohistological findings was evident. en-copyright= kn-copyright= en-aut-name=IshidaMotohisa en-aut-sei=Ishida en-aut-mei=Motohisa kn-aut-name=石田元久 kn-aut-sei=石田 kn-aut-mei=元久 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部口腔外科学教室 en-keyword=放射線照射 kn-keyword=放射線照射 en-keyword=血管像 kn-keyword=血管像 en-keyword=循環障害 kn-keyword=循環障害 en-keyword=下顎骨壊死 kn-keyword=下顎骨壊死 en-keyword=腐骨形成 kn-keyword=腐骨形成 END start-ver=1.4 cd-journal=joma no-vol=92 cd-vols= no-issue=3-4 article-no= start-page=387 end-page=392 dt-received= dt-revised= dt-accepted= dt-pub-year=1980 dt-pub=19800430 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Candidiasis attributable to gastric ulcer kn-title=胃潰瘍に随伴せるCandida症に就いて en-subtitle= kn-subtitle= en-abstract=Candidiasis induced by antibiotics or steroid substances has often been reported. However, we found candidiasis in woman of 47 years which followed gastric ulcer without administration of such substances. This is extremely rare in Japan. kn-abstract=Candida症は真菌の一種のカンジダ属,特にCandida albicansによって起される疾病であり,本来は正常な皮膚,粘膜,糞便,喀痰,尿などに常在して人体に害を及ぼさない.近年各種の抗生物質,ステロイド製剤の開発に伴って,適応疾患に此等が容易に投与されており,此等薬剤の使用による副作用として色々な現象が現われて来ているが,そのうちの重要なる疾患の一つにCandida症が挙げられる.此のCandida症は上記薬剤の投与に依るのみならず,他疾患に基づく抵抗性の低下した患者においても認められることは周知の如くであり,例えば,白血病,再生不良性貧血,糖尿病等の患者,化学療法を受けた悪性腫瘍患者にも好発し易い.此等の場合多くは食道Candida症として見られることが多いが,今回我々の遭遇した患者は上記薬剤の投与もなく,心窩部痛を主訴として来院したものであり,食道,胃等の上部消化管X線検査によって,胃体中部小彎側に潰瘍像が認められ,潰瘍周辺部の粘膜像も不整を示しており一応悪性化が考えられた症例である.症例.患者は47才,主婦.主訴:約2週間前よりの心窩部痛.家族歴:特記すべきものなし.既往歴:生来健康であり薬剤常用等の経験はない.現病歴約2週間前より心窩部痛を来たし,その疼痛は心窩部をつまみ挙げる様であり特に空腹時に強く感じられ,時には夜中にも疼痛を来たすことがあった. 臨床検査 RBC,508×10(4),WBC,9200.分画像に異常なし.Hgb.16.0g/dl,MCV 98.0,GOT 26u,GPT 16u.尿一般検査では特に著変を認めない. 上部消化管X線検査 食道造影検査にては造影剤の通過は正常で狭窄等の異常所見なく,又粘膜レリーフ像にも著変は認められなかった.(Fig 1. A,B)胃造影検査では充満像では胃角部の短縮及び胃角上部小彎の不整が認められた.(Fig 2. C)圧迫撮影では小彎側中央部よりや,上方に潰瘍ニッシエがあり(Fig 2. D)潰瘍周辺は不整にして,通常みられる良性胃潰瘍よりもwallの巾が広く,又粘膜像においても潰瘍周辺部の顆粒状隆起,レリーフの不整が見られ,良性潰瘍像と少し異ったレ線像を呈しているので潰瘍癌の疑を持ち胃生検を行なうことにした. 胃内視鏡所見 胃体中部小彎側に大きな潰瘍による陥凹部を認め,その辺縁は平滑であったが,潰瘍部の周辺は隆起し潰瘍表面は不整で出血を認めた.そこで潰瘍部のうち3ヶ所をえらんで組織生検を行った. 生検組織所見 岡山大学医学部病理学教室に依頼した病理診断所見によれば,「Gastric ulcer with candidiasis and repairing mucosa, no malignancy」 であり,間質にはround cell infiltrationがある. bleedingを伴っており,ulcer floorにはfungusが増殖している.再生上皮,異型性は余りない. (Fig.4, E.F.G.H) 以上の結果によりCandidaが増殖している場合には,組織学的に悪性度は認め難い場合でもcancerを完全に否定し得ないこともあり手術に踏切った. 摘出標本組織診断 「Gastric ulcer (Ul-W) and chronic active gastritis, no malignancy.」ulcer floorはnecrotic massとgranulationが著明で此のgranulation changeはadipose tissueに及んでいる(Ul-W).mucosaは比較的異型性は軽度でmalignancyの所見は認められず,間質はround cellのnodular infiltrationが著明に見られた.以上の如く生検並に手術摘出標本の組織所見によって胃レ線所見において悪性像の如く考えられたのは胃潰瘍に併存したCandidiasisの為によって,斯くの如きレ線像を呈したものと思われる.術后経過における種々の臨床検査成績に著変なく患者は順調である. en-copyright= kn-copyright= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=1 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=2 ORCID= en-aut-name=IguchiYoshiko en-aut-sei=Iguchi en-aut-mei=Yoshiko kn-aut-name=井口与志子 kn-aut-sei=井口 kn-aut-mei=与志子 aut-affil-num=3 ORCID= en-aut-name=AkagiKeiko en-aut-sei=Akagi en-aut-mei=Keiko kn-aut-name=赤木螢子 kn-aut-sei=赤木 kn-aut-mei=螢子 aut-affil-num=4 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=5 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=6 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=胃 cadida 症 kn-keyword=胃 cadida 症 en-keyword=X 線診断 kn-keyword=X 線診断 END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=11-12 article-no= start-page=1499 end-page=1505 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19791230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of ulcerative colitis in childhood kn-title=小児潰瘍性大腸炎の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=Ulcerative colitis in childhood is a rare disease in Japan. A 10-year-old male child was admitted to Okayama University Hospital with a chief complaint of mucous and bloody diarrhea. He had been treated conservatively in another hospital, but the symptoms had not improved. Barium enema examination revealed, from the sigmoid to the transverse colon, abnormal barium coating, numerous small niches, disappearance of the network pattern, and faint spiculations along the margins. Endoscopy demonstrated slight edema, hyperemia, easy bleeding and some purulent secretion. Biopsy specimens showed infiltration of lymphocytes, plasma cells and eosinophilic leucocytes in the mucosa. We made a diagnosis of ulcerative colitis. The patient responded poorly to Salazopyrin and Penicillin, but improved considerably with corticosteroids. en-copyright= kn-copyright= en-aut-name=EharaKazuhiko en-aut-sei=Ehara en-aut-mei=Kazuhiko kn-aut-name=江原一彦 kn-aut-sei=江原 kn-aut-mei=一彦 aut-affil-num=1 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=2 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=4 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=5 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=6 ORCID= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=7 ORCID= en-aut-name=SugitaKatsuhiko en-aut-sei=Sugita en-aut-mei=Katsuhiko kn-aut-name=杉田勝彦 kn-aut-sei=杉田 kn-aut-mei=勝彦 aut-affil-num=8 ORCID= en-aut-name=HirakiYoshio en-aut-sei=Hiraki en-aut-mei=Yoshio kn-aut-name=平木祥夫 kn-aut-sei=平木 kn-aut-mei=祥夫 aut-affil-num=9 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=10 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=11 ORCID= en-aut-name=YamamotoMichio en-aut-sei=Yamamoto en-aut-mei=Michio kn-aut-name=山本道夫 kn-aut-sei=山本 kn-aut-mei=道夫 aut-affil-num=12 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=12 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=小児潰瘍性大腸炎 kn-keyword=小児潰瘍性大腸炎 en-keyword=粘血性下痢便 kn-keyword=粘血性下痢便 END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=9-10 article-no= start-page=1127 end-page=1137 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19791030 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Inhibitory effect of cephalanthin on radiation-induced haemolysis of human erythrocytes kn-title=放射線照射による人赤血球の溶血と“セファランチン”による阻止作用 en-subtitle= kn-subtitle= en-abstract= kn-abstract=X-radiation decreases the number of RBC in vivo and accelerates hemolysis in vitro, but the mechanism is still unclear. Taking the view that these phenomena are due to radical formation and active enzyme formation followed by accelerated peroxidation of cell membrane lipid and membrane structural changes we studied the morphological changes of RBC, changes in ion-partition, and the inhibitory effects of drugs. The results were as follows: 1) Hemolysis of human erythrocytes (RBC) was accelerated by x-radiation. The degree of such lysis was proportional to the degree of x-radiation. This lysis was inhibited markedly by the addition of cephalanthin. The inhibitory effect was dependent on the concentration. In high concentrations conversely acceleration occurred. 2) Soon after x-radiation and prior to hemolysis, human RBCs released K(+) bringing about a decrease in the K(+) partition. The time of this decrease paralleled the degree of x-radiation. The K(+)-partition decrease caused by x-radiation was inhibited by the addition of cephalanthin. 3) In parallel with the acceleration of erythrocyte membrane permeability by x-radiation, changes in RBC morphology were more likely, thus causing structural changes in the cell membrane. 4) Cephalanthin protects the RBC from its instability to x-radiation, and at certain concentrations it restores normal morphology to RBC that have an Echinocyte structure, but at high concentrations it makes RBC to assume a stomatocyte shape. 5) The above findings are discussed in terms of cell membrane injury mechanisms and the inhibitory effect of cephalanthin. en-copyright= kn-copyright= en-aut-name=IidaSosuke en-aut-sei=Iida en-aut-mei=Sosuke kn-aut-name=飯田荘介 kn-aut-sei=飯田 kn-aut-mei=荘介 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=アルカロイド kn-keyword=アルカロイド en-keyword=放射線照射 kn-keyword=放射線照射 en-keyword=溶血 kn-keyword=溶血 en-keyword=人赤血球 kn-keyword=人赤血球 en-keyword=形態変化 kn-keyword=形態変化 en-keyword=細胞膜K(+)区画性 kn-keyword=細胞膜K(+)区画性 END start-ver=1.4 cd-journal=joma no-vol=94 cd-vols= no-issue=11-12 article-no= start-page=1037 end-page=1044 dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19821230 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Result of Radiotherapy of Esophageal cancer kn-title=食道癌の放射線治療成績 en-subtitle= kn-subtitle= en-abstract= kn-abstract=During the 6 years from 1969 to 1974, 31 patients with esophageal cancer were treated by radiotherapy with focal doses above 4,000 rad (40Gy). Cobalt 60 gamma rays were employed for the irradiation with parallel-opposing portals. Survival rates for these patients were 45.1% for 1 year, 12.9% for 2 years, 9.7% for 3 and 4 years, and 6.5% for 5 years; they mean survival time was 16.2 months. The results were tabulated according to the tumor types, lengths and sites and according to doses. Two of the 3 cases who survived more than 4 years were irradiated with 10,000 rad (100Gy) and more focal doses including reirradiation of local recurrences. en-copyright= kn-copyright= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=1 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=2 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=3 ORCID= en-aut-name=MizukawaKiichiro en-aut-sei=Mizukawa en-aut-mei=Kiichiro kn-aut-name=水川帰一郎 kn-aut-sei=水川 kn-aut-mei=帰一郎 aut-affil-num=4 ORCID= en-aut-name=WakabayashiHisao en-aut-sei=Wakabayashi en-aut-mei=Hisao kn-aut-name=若林寿生 kn-aut-sei=若林 kn-aut-mei=寿生 aut-affil-num=5 ORCID= en-aut-name=SatohKatashi en-aut-sei=Satoh en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=6 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=7 ORCID= en-aut-name=OhkawaMotoomi en-aut-sei=Ohkawa en-aut-mei=Motoomi kn-aut-name=大川元臣 kn-aut-sei=大川 kn-aut-mei=元臣 aut-affil-num=8 ORCID= en-aut-name=JohjaIkuo en-aut-sei=Johja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=9 ORCID= en-aut-name=KojimaKanji en-aut-sei=Kojima en-aut-mei=Kanji kn-aut-name=児島完治 kn-aut-sei=児島 kn-aut-mei=完治 aut-affil-num=10 ORCID= en-aut-name=KimotoShin en-aut-sei=Kimoto en-aut-mei=Shin kn-aut-name=木本真 kn-aut-sei=木本 kn-aut-mei=真 aut-affil-num=11 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=2 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=4 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=6 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=8 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=9 en-affil= kn-affil=岡山大学医学部放射線医学教室 affil-num=10 en-affil= kn-affil=香川医科大学放射線医学教室 affil-num=11 en-affil= kn-affil=岡山大学医学部放射線医学教室 en-keyword=esophageal cancer kn-keyword=esophageal cancer en-keyword=radiotherapy kn-keyword=radiotherapy en-keyword=survival rate kn-keyword=survival rate END start-ver=1.4 cd-journal=joma no-vol=91 cd-vols= no-issue=5-6 article-no= start-page=555 end-page=560 dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19790630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=A case of chondrosarcoma of rib origin kn-title=肋骨軟骨肉腫の1例 en-subtitle= kn-subtitle= en-abstract= kn-abstract=A 64 year old male was admitted to the Okayama University Medical School Hospital in June 1976. Although the patient had no subjective symptoms, the chest X-ray film revealed a tumor shadow in the left upper lung field. The tumor shadow was 8×9 cm, well demarcated, and homogenous. In 1969, at the time of an episode of pneumonia, the tumor shadow was 3×3 cm. At operation, the tumor was a chondrosarcoma of rib origin. The chest roentgenograms are described in this report. en-copyright= kn-copyright= en-aut-name=MorinoYasuo en-aut-sei=Morino en-aut-mei=Yasuo kn-aut-name=森野靖雄 kn-aut-sei=森野 kn-aut-mei=靖雄 aut-affil-num=1 ORCID= en-aut-name=MorimotoSetsuo en-aut-sei=Morimoto en-aut-mei=Setsuo kn-aut-name=森本節夫 kn-aut-sei=森本 kn-aut-mei=節夫 aut-affil-num=2 ORCID= en-aut-name=SatoKatashi en-aut-sei=Sato en-aut-mei=Katashi kn-aut-name=佐藤功 kn-aut-sei=佐藤 kn-aut-mei=功 aut-affil-num=3 ORCID= en-aut-name=HashimotoKeiji en-aut-sei=Hashimoto en-aut-mei=Keiji kn-aut-name=橋本啓二 kn-aut-sei=橋本 kn-aut-mei=啓二 aut-affil-num=4 ORCID= en-aut-name=JojaIkuo en-aut-sei=Joja en-aut-mei=Ikuo kn-aut-name=上者郁夫 kn-aut-sei=上者 kn-aut-mei=郁夫 aut-affil-num=5 ORCID= en-aut-name=TamaiToyosato en-aut-sei=Tamai en-aut-mei=Toyosato kn-aut-name=玉井豊理 kn-aut-sei=玉井 kn-aut-mei=豊理 aut-affil-num=6 ORCID= en-aut-name=AonoKaname en-aut-sei=Aono en-aut-mei=Kaname kn-aut-name=青野要 kn-aut-sei=青野 kn-aut-mei=要 aut-affil-num=7 ORCID= en-aut-name=TanabeMasatada en-aut-sei=Tanabe en-aut-mei=Masatada kn-aut-name=田辺正忠 kn-aut-sei=田辺 kn-aut-mei=正忠 aut-affil-num=8 ORCID= en-aut-name=UchidaHatsuzo en-aut-sei=Uchida en-aut-mei=Hatsuzo kn-aut-name=内田発三 kn-aut-sei=内田 kn-aut-mei=発三 aut-affil-num=9 ORCID= en-aut-name=ShimizuNobuyoshi en-aut-sei=Shimizu en-aut-mei=Nobuyoshi kn-aut-name=清水信義 kn-aut-sei=清水 kn-aut-mei=信義 aut-affil-num=10 ORCID= affil-num=1 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=2 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=3 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=4 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=5 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=6 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=7 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=8 en-affil= kn-affil=岡山大学医学部放射線科 affil-num=9 en-affil= kn-affil=岡山大学医学部第II外科 affil-num=10 en-affil= kn-affil=岡山大学医学部第II外科 en-keyword=chondrosarcoma kn-keyword=chondrosarcoma en-keyword=rib kn-keyword=rib END