ID | 41334 |
フルテキストURL | |
タイトル(別表記) | Experimental Studies of Sulfa Drugs on Renal Function Report 3. Influences of Sulfisoxazole on Renal Function
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著者 |
水田 栄三郎
岡山大学医学部皮膚科泌尿器科教室
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抄録 | The author has already reported the influence of sulfathiazole and sulfadiazine on renal function. Barnes and Kawarchi have pointed out that the chief factors influencing the renal damages are as followed (1) concentration of drug in the urine, (2) degree of acetylation of the drug, (3) urinary stasis, (4) pH of the urine, (5) temperature of the urine. In this report, the author applied sulfisoxazole to rabbits, as it is less acetylation and toxities than the other sulfa drugs, and the results were as followed. 1. The amounts of the urine was not influenced but GFR, RPF, RBF were obviously decreased by the administration of 0.05 g, RBF were obviously decreased by the administration of 0.05 g, 0.10 g, 0.20 g per 1 kg weight of rabbits for 10 days. 2. The renal insufficiency was paralleled to the amount of sulfisoxazole administrated on rabbits and the renal function was obviously obstructed.
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発行日 | 1959-11-20
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出版物タイトル |
岡山医学会雑誌
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出版物タイトル(別表記) | Journal of Okayama Medical Association
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巻 | 71巻
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号 | 12-1号
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出版者 | 岡山医学会
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出版者(別表記) | Okayama Medical Association
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開始ページ | 7925
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終了ページ | 7932
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ISSN | 0030-1558
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NCID | AN00032489
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資料タイプ |
学術雑誌論文
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オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/71/12-1/71_12-1_7925/_article/-char/ja/
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関連URL | http://www.okayama-u.ac.jp/user/oma/
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言語 |
日本語
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著作権者 | 岡山医学会
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論文のバージョン | publisher
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査読 |
有り
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Eprints Journal Name | joma
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