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フルテキストURL K0006881_abstract_review.pdf K0006881_fulltext.pdf
著者 佐藤 嘉洋|
発行日 2023-09-25
資料タイプ 学位論文
学位授与番号 甲第6881号
学位授与年月日 2023-09-25
学位・専攻分野 博士(医学)
授与大学 岡山大学
言語 英語
著作権者 © 2023 by the authors.
フルテキストURL fulltext.pdf
著者 Umeyama, Tomokazu| Mizutani, Daizu| Ikeda, Yuki| Osterloh, W. Ryan| Yamamoto, Futa| Kato, Kosaku| Yamakata, Akira| Higashi, Masahiro| Urakami, Takumi| Sato, Hirofumi| Imahori, Hiroshi|
発行日 2023-10-17
出版物タイトル Chemical Science
14巻
42号
出版者 Royal Society of Chemistry
開始ページ 11914
終了ページ 11923
ISSN 2041-6520
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 The Author(s).
論文のバージョン publisher
PubMed ID 37920360
DOI 10.1039/d3sc03604a
Web of Science KeyUT 001087000200001
関連URL isVersionOf https://doi.org/10.1039/d3sc03604a
JaLCDOI 10.18926/AMO/65979
フルテキストURL 77_5_553.pdf
著者 Murokawa, Takahiro| Sakamoto, Shinya| Tabuchi, Motoyasu| Sui, Kenta| Ozaki, Kazuhide| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| Yoshida, Hiroshi|
抄録 Gastric cancer with peritoneal metastases is typically a devastating diagnosis. Ligamentum teres hepatis (LTH) metastasis is an extremely rare presentation with only four known cases. Herein, we report salvage surgery of successive metastases to the abdominal wall and LTH in a patient originally presenting with advanced gastric cancer with peritoneal metastasis, leading to long-term survival. A 72-year-old man with advanced gastric cancer underwent curative-intent distal gastrectomy with D2 lymph node dissection for gastric outlet obstruction. During this procedure, three small peritoneal metastases were detected in the lesser omentum, the small mesentery, and the mesocolon; however, intraoperative abdominal lavage cytology was negative. We added cytoreductive surgery for peritoneal metastasis. The pathological diagnosis of the gastric cancer was tubular adenocarcinoma with pT4aN1pM1(PER/P1b)CY0 stage IV (Japanese classification of gastric carcinoma/JCGC 15th), or T4N1M1b stage IV (UICC 7th). Post-operative adjuvant chemotherapy with S-1 (TS-1)+cisplatin (CDDP) was administered for 8 months followed by S-1 monotherapy for 4 months. At 28 months after the initial surgery, a follow-up computed tomography (CT) detected a small mass beneath the upper abdominal wall. The ass showed mild avidity on 18F-fluorodeoxyglucose positron-emission (FDG-PET) CT. Salvage resection was performed for diagnosis and treatment, and pathological findings were consistent with primary gastric cancer metastasis. At 49 months after the initial gastrectomy, a new lesion was detected in the LTH with a similar level of avidity on FDG-PET CT as the abdominal wall metastatic lesion. We performed a second salvage surgery for the LTH tumor, which also showed pathology of gastric cancer metastasis. There has been no recurrence up to 1 year after the LTH surgery. With multidisciplinary treatment the patient has survived almost 5 years after the initial gastrectomy. Curative-intent gastrectomy with cytoreductive surgery followed by adjuvant chemotherapy for advanced gastric cancer with localized peritoneal metastasis might have had a survival benefit in our patient. Successive salvage surgeries for oligometastatic lesions in the abdominal wall and the LTH also yielded favorable outcomes.
キーワード gastric cancer peritoneal metastasis ligamentum teres hepatis oligometastasis salvage surgery
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2023-10
77巻
5号
出版者 Okayama University Medical School
開始ページ 553
終了ページ 559
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899267
Web of Science KeyUT 001110832700001
JaLCDOI 10.18926/AMO/65978
フルテキストURL 77_5_545.pdf
著者 Iwamuro, Masaya| Tanaka, Shouichi| Toyokawa, Tatsuya| Nishimura, Mamoru| Tsuzuki, Takao| Miyahara, Koji| Negishi, Shin| Ohya, Shogen| Tanaka, Takehiro| Otsuka, Motoyuki|
抄録 To determine the endoscopic and clinical features of localized gastric amyloid light-chain (AL) amyloidosis, we retrospectively examined the characteristics of nine patients (eight men and one woman) encountered by the hospitals in our network. Lesions were predominantly flat and depressed with surface vascular dilatation (n=5); others were characterized by subepithelial lesions (n=2), mucosal color change (n=1), and a mass-like morphology with swollen mucosal folds (n=1). Colonoscopy (n=7), video capsule enteroscopy (n=2), serum (n=5) and urine immunoelectrophoresis (n=4), and bone marrow examination (n=3) were performed to exclude involvement of organs other than the stomach. As treatment for gastric lesions of AL amyloidosis, one patient each underwent endoscopic submucosal dissection (n=1) and argon plasma coagulation (n=1), while the remaining seven patients underwent no specific treatment. During a mean follow-up of 4.2 years, one patient died 3.2 years after diagnosis, but the cause of death, which occurred in another hospital, was unknown. The remaining eight patients were alive at the last visit. In conclusion, although localized gastric AL amyloidosis can show various macroscopic features on esophagogastroduodenoscopy, flat, depressed lesions with vascular dilatation on the surface are predominant.
キーワード esophagogastroduodenoscopy gastric lesion amyloidosis light chain
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
77巻
5号
出版者 Okayama University Medical School
開始ページ 545
終了ページ 552
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899266
Web of Science KeyUT 001094245100001
JaLCDOI 10.18926/AMO/65975
フルテキストURL 77_5_527.pdf
著者 Ando, Miho| Hanayama, Yoshihisa| Nishimura, Yoshito| Hagiya, Hideharu| Otsuka, Fumio|
抄録 Retroperitoneal fibrosis (RPF) is a rare cause of hydronephrosis and progressive renal dysfunction with unidentified origin. RPF is categorized into idiopathic RPF with/without immunoglobulin G4 (IgG4)-related disease (IgG4-RD), and secondary RPF. Identifying the underlying cause is challenging and often associated with delayed diagnosis or therapeutic interventions. We investigated RPF’s clinical characteristics based on different etiologies and factors that may help distinguish the underlying causes. We analyzed the cases of 49 patients with RPF that was radiographically diagnosed at our institution (2008-2022). The cohort was 77.6% males; 75.5% had idiopathic RPF and 24.5% had secondary RPF. Among the idiopathic patients, 54.1% had IgG4-RD. The patients were likely to have abdominal pain, lower back pain/lumbago, and constitutional symptoms including generalized fatigue and fever. The idiopathic patients were likely to have higher serum IgG4 and IgG levels and lower serum C3 levels compared to secondary RPF. The IgG4-RPF patients were likely to have higher serum IgG4 levels and lower serum C-reactive protein, ferritin, and C3 levels compared to the idiopathic RPF patients without IgG4-RD. These findings might reflect underlying systemic inflammatory responses. Comprehensive laboratory testing, including serum inflammatory markers and immunological panels, is recommended for radiologically diagnosed RPF patients.
キーワード retroperitoneal fibrosis IgG4-related disease malignancy
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
77巻
5号
出版者 Okayama University Medical School
開始ページ 527
終了ページ 536
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899264
Web of Science KeyUT 001108661600010
JaLCDOI 10.18926/AMO/65974
フルテキストURL 77_5_517.pdf
著者 Horiguchi, Shigeru| Matsumoto, Kazuyuki| Morimoto, Kosaku| Matsumi, Akihiro| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Tsutsumi, Koichiro| Kato, Hironari|
抄録 We investigated the effect of modified FOLFIRINOX (mFFX) in unresectable pancreatic cancer by retrospectively analyzing the cases of 43 patients who underwent BRCA testing (germline, n=11; somatic, n=26; both germline and somatic, n=6). The association between BRCA mutations and therapeutic effect was clarified. Six patients tested positive for germline pathogenic variants. Familial pancreatic cancer (33% vs. 3%, p=0.006) and peritoneal disseminated lesions (66% vs. 8%, p<0.001) were significantly more common in patients with germline pathogenic variants. The partial response (PR) rate was 100% in the germline BRCA-positive patients, and 27% in the germline BRCA-negative patients (p<0.001). The median progression-free survival (PFS) was not reached for any germline BRCA-positive patients but was 9.0 months for the germline BRCA-negative patients (p=0.042). Patients with stage IV BRCA-associated pancreatic cancer had better overall survival than those with non-BRCA-associated pancreatic cancer, although the difference was nonsignificant (not reached vs. 655 days, p=0.061). Our results demonstrate that a PR and prolonged PFS can be expected in germline BRCA-positive patients after treatment with mFFX. Our findings also suggest that germline BRCA pathogenic variants may be useful as biomarkers for the therapeutic effect of mFFX in patients with pancreatic cancer.
キーワード BRCA FOLFIRINOX pancreatic cancer progression-free survival pathogenic variant
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
77巻
5号
出版者 Okayama University Medical School
開始ページ 517
終了ページ 525
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899263
Web of Science KeyUT 001108661600009
JaLCDOI 10.18926/AMO/65973
フルテキストURL 77_5_511.pdf
著者 Sato, Kohei| Tsuji, Hironori| Yorimitsu, Masanori| Uehara, Takenori| Okazaki, Yuki| Takao, Shinichiro| Hata, Toshiaki| Fukuoka, Shiro| Noda, Tomoyuki| Kanda, Hideyuki| Ozaki, Toshifumi|
抄録 Sarcopenia and malnutrition are increasing in older adults and are reported risk factors for functional impairment after hip fracture surgery. This study aimed to investigate the associations between skeletal muscle mass loss, malnutrition, and postoperative walking ability in patients with hip fracture. We retrospectively reviewed patients who underwent intertrochanteric fracture surgery at our institute. The psoas muscle index, controlling nutritional status score, and functional ambulation category (FAC) were used to evaluate skeletal muscle mass, nutritional status, and walking ability, respectively. Six months after surgery, walking ability was assessed as either “gait disturbance” or “independent gait”. Multivariate binomial logistic regression analysis, with skeletal muscle mass, nutritional status, and other factors, was used to predict the risk of being assigned to the gait disturbance group. This study included 95 patients (mean age, 85.2 years; 70 women). Sixty-six patients had low skeletal muscle mass, 35 suffered from malnutrition, and 28 had both. Malnutrition and low skeletal muscle mass were significantly associated with postoperative gait disturbance (FAC < 3). Preoperative low skeletal muscle mass and malnutrition were risk factors for postoperative poor walking ability. Further preventive interventions focusing on skeletal muscle mass and nutritional status are required.
キーワード sarcopenia nutrition geriatric hip fracture psoas muscle index controlling nutritional status score
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
77巻
5号
出版者 Okayama University Medical School
開始ページ 511
終了ページ 516
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899262
Web of Science KeyUT 001108661600008
JaLCDOI 10.18926/AMO/65968
フルテキストURL 77_5_461.pdf
著者 Homma, Daisuke| Minato, Izumi| Imai, Norio| Miyasaka, Dai| Sakai, Yoshinori| Horigome, Yoji| Suzuki, Hayato| Dohmae, Yoichiro| Endo, Naoto|
抄録 This study aimed to determine which muscle the gluteus maximus, gluteus medius, gluteus minimus (Gmin), or tensor fasciae latae (TFL) contributes most to hip abduction strength and to identify effective sites for cross-sectional area (CSA) Gmin and TFL measurement in hip osteoarthritis (OAhip) patients. Twenty-eight patients with OAhip were included. The muscle CSA and volume were determined using magnetic resonance imaging. Peak isometric strength was determined using hand-held dynamometry. Muscle volumes were normalized to the total muscle volume of hip abductors. Multiple regression analysis was performed. The difference between the CSA of Gmin and TFL was calculated, and correlations with volume and muscle strength were determined. Gmin volume was related to abductor muscle strength (p=0.042). The peak CSA of the Gmin correlated with muscle volume and strength. The CSA of the TFL correlated with volume, with no difference between the CSA of the most protruding part of the lesser trochanter and peak CSA. Gmin volume was strongly related to abductor muscle strength. Peak CSA is a useful parameter for assessing the CSA of the Gmin among patients with OAhip. The CSA of the TFL should be measured at the most protruding part of the lesser trochanter.
キーワード gluteus minimus tensor fasciae latae cross-sectional area muscle volume hip osteoarthritis
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
77巻
5号
出版者 Okayama University Medical School
開始ページ 461
終了ページ 469
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899257
Web of Science KeyUT 001108661600003
JaLCDOI 10.18926/AMO/65966
フルテキストURL 77_5_443.pdf
著者 Miyaji, Chikara| Takao, Soshi| Habu, Hiroshi| Matsumoto, Naomi| Aoo, Ken| Nishita, Yosuke| Tsuri, Masao| Yorifuji, Takashi|
抄録 This study examined whether participation in an art project was associated with higher social capital (SC). We conducted a questionnaire survey from November 2021 to March 2022 among residents aged 20 years or older of Naoshima, an island in Kagawa Prefecture, Japan. Before the survey, the Setouchi Triennale had been held on Naoshima four times, starting in 2010. We calculated propensity scores for Triennale participation and performed propensity score matching. We then compared cognitive and structural SC by Triennale participation and found significant differences, respectively. We adopted a conditional ordered logistic regression analysis with propensity score matching for cognitive or structural SC, and found adjusted odd ratios of 2.913 (95%CI, 1.846-4.596) for cognitive SC and 4.535 (95%CI, 2.839-7.244) for structural SC. Our findings suggest that Triennale participation enhanced the cognitive aspect of SC while also building structural SC.
キーワード social capital art project propensity score matching
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-10
77巻
5号
出版者 Okayama University Medical School
開始ページ 443
終了ページ 449
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37899255
Web of Science KeyUT 001108661600001
フルテキストURL fulltext.pdf
著者 Sada, Ken-ei| Katayama, Yu| Asano, Yosuke| Hayashi, Keigo| Miyawaki, Yoshia| Ohashi, Keiji| Katsuyama, Eri| Katsuyama, Takayuki| Takano-Narazaki, Mariko| Matsumoto, Yoshinori| Yoshimi, Ryusuke| Shimojima, Yasuhiro| Ohno, Shigeru| Kajiyama, Hiroshi| Ichinose, Kunihiro| Sato, Shuzo| Fujiwara, Michio| Yajima, Nobuyuki|
キーワード systemic lupus erythematosus glucocorticoids outcome assessment health care epidemiology
発行日 2022-09-27
出版物タイトル Lupus Science & Medicine
9巻
1号
出版者 BMJ
開始ページ e000772
ISSN 2053-8790
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Author(s) (or their employer(s)) 2022.
論文のバージョン publisher
PubMed ID 36167483
DOI 10.1136/lupus-2022-000772
Web of Science KeyUT 000861425300002
関連URL isVersionOf https://doi.org/10.1136/lupus-2022-000772
フルテキストURL fulltext.pdf
著者 Miyamoto, Kazuya| Matsumoto, Kazuyuki| Obata, Taisuke| Sato, Ryosuke| Matsumi, Akihiro| Morimoto, Kosaku| Ogawa, Taiji| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Horiguchi, Shigeru| Tsutsumi, Koichiro| Kato, Hironari| Otsuka, Motoyuki|
キーワード Balloon-assisted endoscopy Propofol Diazepam Sedation
備考 The version of record of this article, first published in BMC Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12876-023-02936-8|
発行日 2023-09-04
出版物タイトル BMC Gastroenterology
23巻
1号
出版者 BMC
開始ページ 296
ISSN 1471-230X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023.
論文のバージョン publisher
PubMed ID 37667224
DOI 10.1186/s12876-023-02936-8
Web of Science KeyUT 001063014700002
関連URL isVersionOf https://doi.org/10.1186/s12876-023-02936-8
フルテキストURL fulltext.pdf
著者 SUGINO, Yosuke| SATO, Taiki| YAMAMOTO, Yuki| KIMURA, Koji|
キーワード Bovine Secreted proteins Three-dimensional culture Uterine glands
発行日 2022
出版物タイトル Journal of Reproduction and Development
68巻
4号
出版者 Japanese Society of Animal Reproduction
開始ページ 254
終了ページ 261
ISSN 0916-8818
NCID AA10936678
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2022 The Society for Reproduction and Development
論文のバージョン publisher
PubMed ID 35644574
DOI 10.1262/jrd.2022-029
Web of Science KeyUT 000836697600004
関連URL isVersionOf https://doi.org/10.1262/jrd.2022-029
フルテキストURL fulltext20230829-01.pdf
著者 Sato, Yukiyo| Hisano, Sakae| Suzuki, Nobuhiro|
キーワード Virus-virus interaction RNA viruses Capsidless Fungal viruses Plant pathogenic fungi Yadokarivirus Megabirnavirus Reverse genetics
発行日 2023-09
出版物タイトル Virus Research
334巻
出版者 Elsevier BV
開始ページ 199155
ISSN 0168-1702
NCID AA10642076
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 The Author(s).
論文のバージョン publisher
PubMed ID 37356581
DOI 10.1016/j.virusres.2023.199155
Web of Science KeyUT 001038861300001
関連URL isVersionOf https://doi.org/10.1016/j.virusres.2023.199155
JaLCDOI 10.18926/AMO/65751
フルテキストURL 77_4_407.pdf
著者 Hotta, Kensuke| Kobayashi, Takaomi|
抄録 This study aimed to investigate the usefulness of force-controlled pelvic stress radiographs in the evaluation and treatment of fragility fractures of the pelvis (FFP) using a functional treatment strategy. We conducted a retrospective study of 55 geriatric patients with FFP who underwent pelvic stress radiographs on admission. The differences in the sacral width, pelvic ring width, and medial femoral head width between the radiographs with and without the Sam Sling II M size were defined as Δ sacral width, Δ pelvic ring width, and Δ medial femoral head width, respectively. We used Pearson’s correlation test to assess the relationship between the degree of radiographic instability and the Johns Hopkins highest level of mobility scale (JH-HLM) at 10-days postadmission. Conventional receiver-operating-characteristic curve analysis was used to identify cases requiring surgery using the best cutoff value for radiographic instability. The JH-HLM was significantly correlated with Δ sacral width (r=−0.401, p=0.017), but not with Δ pelvic ring width (r=−0.298, p=0.080) nor with Δ medial femoral head width (r= −0.261, p=0.128). The best cutoff value of Δ sacral width in identifying surgical cases was 10.7 mm (sensitivity 75.0%, specificity 98.0%). Force-controlled pelvic stress radiographs could be helpful in assessing the need for surgery on admission.
キーワード fragility fracture of the pelvis functional treatment strategy Sam Sling stress radiograph Johns Hopkins highest level of mobility scale
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-08
77巻
4号
出版者 Okayama University Medical School
開始ページ 407
終了ページ 414
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37635141
Web of Science KeyUT 001163659800001
フルテキストURL fulltext.pdf
著者 Tsumura, Hideki| Fukuda, Mari| Hisamatsu, Takashi| Sato, Rie| Tsuchie, Rina| Kanda, Hideyuki|
備考 The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-38623-7|
発行日 2023-07-17
出版物タイトル Scientific Reports
13巻
1号
出版者 Nature Portfolio
開始ページ 11491
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023
論文のバージョン publisher
PubMed ID 37460653
DOI 10.1038/s41598-023-38623-7
Web of Science KeyUT 001032784200004
関連URL isVersionOf https://doi.org/10.1038/s41598-023-38623-7
フルテキストURL fulltext.pdf correction.pdf
著者 Matsumoto, Naomi| Kadowaki, Tomoka| Takanaga, Satoe| Shigeyasu, Yoshie| Okada, Ayumi| Yorifuji, Takashi|
キーワード COVID-19 Adolescence Eating disorders Schizophrenia Mood disorders Somatoform disorders Child and adolescent mental health Interrupted time-series
発行日 2023-07-07
出版物タイトル BMC Public Health
23巻
1号
出版者 BMC
開始ページ 1308
ISSN 1471-2458
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023.
論文のバージョン publisher
PubMed ID 37420207
DOI 10.1186/s12889-023-16228-z
Web of Science KeyUT 001024972900005
関連URL isVersionOf https://doi.org/10.1186/s12889-023-16228-z
フルテキストURL fulltext.pdf
著者 Fujii, Shota| Sato, Takayuki| Aoki, Sho| Tsuda, Yu| Kawaguchi, Nobutaka| Shigemoto, Tomohiro| Terada, Masato|
キーワード Cloaking cyber security geofencing malcious host time-series
発行日 2023-05-29
出版物タイトル IEEE Access
11巻
出版者 Institute of Electrical and Electronics Engineers
開始ページ 52750
終了ページ 52762
ISSN 2169-3536
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン publisher
DOI 10.1109/ACCESS.2023.3280815
Web of Science KeyUT 001005635100001
関連URL isVersionOf https://doi.org/10.1109/ACCESS.2023.3280815
フルテキストURL fulltext.pdf
著者 Komoto, Satoshi| Noma, Kazuhiro| Kato, Takuya| Kobayashi, Teruki| Nishiwaki, Noriyuki| Narusaka, Toru| Sato, Hiroaki| Katsura, Yuki| Kashima, Hajime| Kikuchi, Satoru| Ohara, Toshiaki| Tazawa, Hiroshi| Fujiwara, Toshiyoshi|
キーワード cancer-associated fibroblast chemotherapy radiotherapy esophageal cancer tumor microenvironment
発行日 2023-05-30
出版物タイトル Cancers
15巻
11号
出版者 MDPI
開始ページ 2971
ISSN 2072-6694
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 by the authors.
論文のバージョン publisher
PubMed ID 37296933
DOI 10.3390/cancers15112971
Web of Science KeyUT 001006082400001
関連URL isVersionOf https://doi.org/10.3390/cancers15112971
JaLCDOI 10.18926/AMO/65497
フルテキストURL 77_3_319.pdf
著者 Kashihara, Kenichi|
抄録 I report a case of arterial spine-labelled MR imaging (ASL)-detected cerebral hypoperfusion during migraine and panic attacks. A 20-year-old woman with a history of headache for 6 years and independent panic attacks for 3 years was transferred to Okayama Kyokuto Hospital for panic attacks. On that day, she had had severe headache that was improved by taking non-steroidal anti-inflammatory drug, but panic attacks initiated. On arrival, she also complained of a mild headache. ASL revealed cerebral hypoperfusion in the right temporo-occipital region. The threshold to induce panic attacks in migraine patients could be lowered by the physiopathology underlying migraine attacks.
キーワード migraine panic attack arterial spine-labelled magnetic resonance imaging aura cortical spreading depression
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2023-06
77巻
3号
出版者 Okayama University Medical School
開始ページ 319
終了ページ 321
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37357633
Web of Science KeyUT 001026279600010
JaLCDOI 10.18926/AMO/65495
フルテキストURL 77_3_301.pdf
著者 Kato, Takahide| Miyoshi, Seigo| Hamada, Chizuru| Sano, Yoshifumi| Nogami, Naoyuki| Yamaguchi, Osamu| Hamaguchi, Naohiko|
抄録 Acute exacerbation (AE) of interstitial lung disease (ILD) is a severe complication of lung resection in lung cancer patients with ILD (LC-ILD). This study aimed to assess the predictive value of comorbidities other than ILD for postoperative AE in patients with LC-ILD. We retrospectively evaluated 68 patients with LC-ILD who had undergone lung resection. We classified them into two groups: those who had developed postoperative AE within 30 days after resection and those who had not. We analyzed patient characteristics, high-resolution computed tomography findings, clinical data, pulmonary function, and intraoperative data. The incidence of postoperative AEs was 11.8%. In univariate analysis, performance status (PS), honeycombing, forced vital capacity (FVC), and high hemoglobin A1c (HbA1c) levels without comorbidities were significantly associated with postoperative AE. Patients were divided into two groups according to cutoff levels of those four variables as determined by receiver operating characteristic curves, revealing that the rates of patients without postoperative AE differed significantly between groups. The present results suggested that preoperative comorbidities other than ILD were not risk factors for postoperative AE in patients with LC-ILD. However, a high preoperative HbA1c level, poor PS, low FVC, and honeycombing may be associated with postoperative AE of LC-ILD.
キーワード lung cancer interstitial lung disease acute exacerbation comorbidity
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-06
77巻
3号
出版者 Okayama University Medical School
開始ページ 301
終了ページ 309
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 37357631
Web of Science KeyUT 001026279600008