検索結果 1452 件
フルテキストURL | fulltext20230120-2.pdf fig20230120-2.pdf |
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著者 | Hiranaka, Takaaki| Furumatsu, Takayuki| Yokoyama, Yusuke| Kintaka, Keisuke| Higashihara, Naohiro| Tamura, Masanori| Kawada, Koki| Xue, Haowei| Hamada, Masanori| Ozaki, Toshifumi| |
キーワード | Medial meniscus posterior root tear Magnetic resonance imaging Medial meniscus extrusion Pullout repair Type 2 tear |
備考 | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00167-022-07293-9| |
発行日 | 2022-12-25 |
出版物タイトル | Knee Surgery, Sports Traumatology, Arthroscopy |
巻 | 31巻 |
号 | 6号 |
出版者 | Springer Science and Business Media LLC |
開始ページ | 2323 |
終了ページ | 2330 |
ISSN | 0942-2056 |
NCID | AA10973641 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s) under exclusive licence to European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2022 |
論文のバージョン | author |
PubMed ID | 36566386 |
DOI | 10.1007/s00167-022-07293-9 |
Web of Science KeyUT | 000903833100001 |
関連URL | isVersionOf https://doi.org/ |
フルテキストURL | fulltext.pdf |
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著者 | Shi, Chenrui| Funabiki, Nobuo| Huo, Yuanzhi| Mentari, Mustika| Suga, Kohei| Toshida, Takashi| |
キーワード | digitization printed table OCR Python OpenCV Tesseract |
発行日 | 2022-12-11 |
出版物タイトル | Algorithms |
巻 | 15巻 |
号 | 12号 |
出版者 | MDPI |
開始ページ | 471 |
ISSN | 1999-4893 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2022 by the authors. |
論文のバージョン | publisher |
DOI | 10.3390/a15120471 |
Web of Science KeyUT | 000900452900001 |
関連URL | isVersionOf https://doi.org/10.3390/a15120471 |
フルテキストURL | fulltext.pdf |
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著者 | Misawa, Masaaki| Hokyo, Hinata| Fukushima, Shogo| Shimamura, Kohei| Koura, Akihide| Shimojo, Fuyuki| Kalia, Rajiv K.| Nakano, Aiichiro| Vashishta, Priya| |
発行日 | 2022-11-14 |
出版物タイトル | Scientific Reports |
巻 | 12巻 |
号 | 1号 |
出版者 | Nature Portfolio |
開始ページ | 19458 |
ISSN | 2045-2322 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s) 2022 |
論文のバージョン | publisher |
PubMed ID | 36376359 |
DOI | 10.1038/s41598-022-24004-z |
Web of Science KeyUT | 000883823800060 |
関連URL | isVersionOf https://doi.org/10.1038/s41598-022-24004-z |
フルテキストURL | fulltext.pdf |
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著者 | Sukegawa, Shintaro| Yoshii, Kazumasa| Hara, Takeshi| Tanaka, Futa| Yamashita, Katsusuke| Kagaya, Tutaro| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Nagatsuka, Hitoshi| Furuki, Yoshihiko| |
発行日 | 2022-07-27 |
出版物タイトル | Plos One |
巻 | 17巻 |
号 | 7号 |
出版者 | Public Library Science |
開始ページ | e0269016 |
ISSN | 1932-6203 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2022 Sukegawa et al. |
論文のバージョン | publisher |
PubMed ID | 35895591 |
DOI | 10.1371/journal.pone.0269016 |
Web of Science KeyUT | 000880183400018 |
関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0269016 |
JaLCDOI | 10.18926/AMO/64127 |
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フルテキストURL | 76_6_749.pdf |
著者 | Takami, Masanari| Yukawa, Yasutsugu| Noda, Yusuke| Yoshida, Munehito| Yamada, Hiroshi| |
抄録 | We provide the first report of successful salvage surgery for a post-C1 laminectomy symptomatic recurrence of a retro-odontoid pseudotumor (ROP) that caused myelopathy. The 72-year-old Japanese woman presented with an ROP causing symptomatic cervical myelopathy. With ultrasonography support, we performed the enucleation of the ROP via a transdural approach and fusion surgery for the recurrence of the mass. At the final observation 2-year post-surgery, MRI demonstrated the mass’s regression and spinal cord decompression, and the patient’s symptoms had improved. Our strategy is an effective option for a symptomatic recurrence of ROP. |
キーワード | recurrent retro-odontoid pseudotumor salvage surgery transdural resection C1 laminectomy ultra-sonography |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-12 |
巻 | 76巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 749 |
終了ページ | 754 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36549779 |
Web of Science KeyUT | 000905195100017 |
JaLCDOI | 10.18926/AMO/64126 |
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フルテキストURL | 76_6_743.pdf |
著者 | Tanaka, Masato| Suthar, Hardik| Desai, Dhvanit| Yamauchi, Taro| Arataki, Shinya| Fujiwara, Yoshihiro| Uotani, Koji| Oda, Yoshiaki| Misawa, Haruo| |
抄録 | We describe a floating technique via a posterolateral approach with intraoperative O-arm navigation to facilitate decompression of the spinal cord in thoracic myelopathy due to severe ossification of the posterior longitudinal ligament (OPLL). A 62-year-old man with myelopathy due to thoracic OPLL had left-leg muscle weakness, urinary disturbance, and spastic gait. Bilateral leg pain and gait disturbance had persisted for 2 years. He was successfully treated by the posterolateral OPLL floating procedure and posterior pedicle fixation under O-arm navigation. At a 2-year follow-up, manual muscle testing results and sensory function of the left leg had recovered fully. His cervical Japanese Orthopedic Association score had improved from 5/12 to 11/12. The novel intraoperative O-arm navigation-guided posterolateral floating procedure for thoracic OPLL is effective for achieving precise decompression and strong fixation with a posterior approach only and can provide an excellent result for severe thoracic OPLL without the risk of adverse events from intraoperative radiation. |
キーワード | ossification of the posterior longitudinal ligament floating method navigation surgery C-arm free |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-12 |
巻 | 76巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 743 |
終了ページ | 748 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36549778 |
Web of Science KeyUT | 000905195100016 |
JaLCDOI | 10.18926/AMO/64125 |
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フルテキストURL | 76_6_737.pdf |
著者 | Yamaoka, Masakazu| Yamamoto, Yumi| Minami, Eriko| |
抄録 | Paraplegia after an operation for acute aortic dissection Stanford type A (AADA) is fairly uncommon, and there is no consensus about optimal treatment. We present a case in which cerebrospinal fluid drainage (CSFD) and permissive hypertension were used for treatment of paraplegia. When the patient showed complete bilateral paraplegia after operation for AADA, we immediately began CSFD and maintained mean arterial blood pressure at over 90 mmHg. His neurological deficit gradually recovered, and he was eventually able to walk without support. The combination of CSFD and permissive hypertension could be a first-line emergent treatment for postoperative paraplegia after AADA surgery. |
キーワード | paraplegia acute aortic dissection cerebrospinal drainage permissive hypertension |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-12 |
巻 | 76巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 737 |
終了ページ | 742 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36549777 |
Web of Science KeyUT | 000905195100015 |
JaLCDOI | 10.18926/AMO/64124 |
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フルテキストURL | 76_6_731.pdf |
著者 | Kamamura, Maho| Higaki, Fumiyo| Sasada, Susumu| Matsushita, Toshi| Yasuhara, Takao| Date, Isao| Hiraki, Takao| |
抄録 | We report a rare case of idiopathic spinal cord herniation (ISCH) with a history of cerebrospinal fluid (CSF) leakage. ISCH is a protrusion of the spinal cord through a dural defect. Thin constructive interference in steady-state (CISS) images clearly demonstrated the herniated cord in the present case. The myelopathy worsened and the patient underwent surgery for reduction of herniated spinal cord; the dural defect was filled by placing collagen matrix graft (DuraGen®) between the inner and outer dural layers. The patient’s symptoms have improved without relapse for 8 months since surgery. This method may be a good surgical option for cases of spinal cord herniation. |
キーワード | cerebrospinal fluid leakage constructive interference in steady state collagen matrix graft magnetic resonance image spinal cord herniation |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-12 |
巻 | 76巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 731 |
終了ページ | 736 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36549776 |
Web of Science KeyUT | 000905195100014 |
JaLCDOI | 10.18926/AMO/64115 |
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フルテキストURL | 76_6_651.pdf |
著者 | Bright Osman Abugri| Matsusaki, Takashi| Ren, Wanxu| Morimatsu, Hiroshi| |
抄録 | Maintaining perioperative normothermia decreases the post-surgery surgical site infection (SSI) rate. We investigated whether SSI is associated with intraoperative hypothermia in total hip (THA) and total knee (TKA) arthroplasties by retrospectively analyzing 297 THA and TKA cases. The patients’ intraoperative core body temperature (BT) was measured by bladder catheter or forehead sensor. We evaluated the associations between SSI and intraoperative BT and other variables and patient characteristics. Fifty-six patients (18.8%) had hypothermia (BT <36°C); 43 developed SSI (14.5%); only five had hypothermia (11.6%). Intraoperative hypothermia and SSI were not significantly associated. The SSI group had more men (34.9% vs. 18.1%) and THA patients (77.4%), a longer mean surgical duration (174.3 vs. 143.5 mins), and a higher average BT (36.4°C vs. 36.2°C) than the no-SSI group. The SSI patients had a higher intraoperative BT. A multivariable analysis revealed that SSI was associated with male sex (OR 2.3, 95%CI: 1.031-4.921, p=0.042), longer surgery (OR, 1.01, 95%CI: 1.003-1.017, p=0.004), THA (OR 3.6, 95%CI: 1.258-10.085, p=0.017), and intraoperative BT >36.0°C (OR 3.6, 95%CI: 1.367-9.475, p=0.009). Intraoperative hypothermia was not associated with SSI in adults who underwent THA or TKA. These results suggest that hypothermia might not be the problem for SSI. |
キーワード | hypothermia surgical site infection total hip arthroplasty (THA) knee arthroplasty (TKA) |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-12 |
巻 | 76巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 651 |
終了ページ | 660 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36549767 |
Web of Science KeyUT | 000905195100005 |
JaLCDOI | 10.18926/AMO/64113 |
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フルテキストURL | 76_6_635.pdf |
著者 | Zhang, Cuicui| Ji, Yanan| Wang, Qin| Ruan, Lianying| |
抄録 | To investigate the association between serum miR-338-3p levels and neonatal acute respiratory distress syndrome (ARDS) and its mechanism. The relative miR-338-3p expression in serum was detected by quantitative real-time RT-PCR. Interleukin-1beta (IL-1β), IL-6, and tumor necrosis factor-alpha (TNF-α) levels were detected by ELISAs. A receiver operating characteristic (ROC) curve analysis of serum miR-338-3p evaluated the diagnosis of miR-338-3p in neonatal ARDS. Pearson’s correlation analysis evaluated the correlation between serum miR-338-3p and neonatal ARDS clinical factors. Flow cytometry evaluated apoptosis, and a CCK-8 assay assessed cell viability. A luciferase assay evaluated the miR-338-3p/AKT3 relationship. The miR- 338-3p expression was decreased in neonatal ARDS patients and in lipopolysaccharide (LPS)-treated cells. The ROC curve showed the accuracy of miR-338-3p for evaluating neonatal ARDS patients. The correlation analysis demonstrated that miR-338-3p was related to PRISM-III, PaO2/FiO2, oxygenation index, IL-1β, IL-6, and TNF-α in neonatal ARDS patients. MiR-338-3p overexpression inhibited the secretion of inflammatory components, stifled cell apoptosis, and LPS-induced advanced cell viability. The double-luciferase reporter gene experiment confirmed that miR-338-3p negatively regulates AKT3 mRNA expression. Serum miR-338-3p levels were related to the diagnosis and severity of neonatal ARDS, which may be attributed to its regulatory effect on inflammatory response in ARDS. |
キーワード | miR-338-3p AKT3 neonatal ARDS inflammation diagnosis |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-12 |
巻 | 76巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 635 |
終了ページ | 643 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36549765 |
Web of Science KeyUT | 000905195100003 |
JaLCDOI | 10.18926/AMO/64111 |
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フルテキストURL | 76_6_617.pdf |
著者 | Kobayashi, Katsuhiro| Shibata, Takashi| Tsuchiya, Hiroki| Akiyama, Tomoyuki| |
抄録 | We developed an artificial intelligence (AI) technique to identify epileptic discharges (spikes) in pediatric scalp electroencephalograms (EEGs). We built a convolutional neural network (CNN) model to automatically classify steep potential images into spikes and background activity. For the CNN model’ training and validation, we examined 100 children with spikes in EEGs and another 100 without spikes. A different group of 20 children with spikes and 20 without spikes were the actual test subjects. All subjects were ≥ 3 to < 18 years old. The accuracy, sensitivity, and specificity of the analysis were >0.97 when referential and combination EEG montages were used, and < 0.97 with a bipolar montage. The correct classification of background activity in individual patients was significantly better with a referential montage than with a bipolar montage (p=0.0107). Receiver operating characteristic curves yielded an area under the curve > 0.99, indicating high performance of the classification method. EEG patterns that interfered with correct classification included vertex sharp transients, sleep spindles, alpha rhythm, and low-amplitude ill-formed spikes in a run. Our results demonstrate that AI is a promising tool for automatically interpreting pediatric EEGs. Some avenues for improving the technique were also indicated by our findings. |
キーワード | neural network deep learning electroencephalogram children spike |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-12 |
巻 | 76巻 |
号 | 6号 |
出版者 | Okayama University Medical School |
開始ページ | 617 |
終了ページ | 624 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36549763 |
Web of Science KeyUT | 000905195100001 |
フルテキストURL | K0006714_abstract_review.pdf K0006714_summary.pdf |
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著者 | 张 妍亭| |
発行日 | 2022-09-22 |
資料タイプ | 学位論文 |
学位授与番号 | 甲第6714号 |
学位授与年月日 | 2022-09-22 |
学位・専攻分野 | 博士(理学) |
授与大学 | 岡山大学 |
言語 | 英語 |
JaLCDOI | 10.18926/AMO/64042 |
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フルテキストURL | 76_5_597.pdf |
著者 | Watanabe, Shiho| Watanabe, Toshiyuki| Yamada, Kiyoshi| Namba, Yuzaburo| Kimata, Yoshihiro| |
抄録 | Gender affirming surgery (GAS) has important impacts for people with gender incongruence (GI), both physically and socially. As the societal acceptance of gender diversity spreads, the number of individuals with GI who wish to be identified as the gender of their choice is increasing. Indeed, many elderly people who have lived a long time with GI now wish to undergo GAS, but face greater surgical risks due to greater burdens of underlying medical conditions. Generally, vaginoplasty is performed for transwomen; however, this surgery is time-consuming and involves heavy bleeding, and thus, should be avoided in elderly people. A less invasive technique is needed. In this article, we describe a new, less invasive genital feminizing surgical technique for transwomen with reports from two clinical cases. We present this novel technique as a safe, aesthetic, and cost-effective option for gender-affirming surgery for transwomen. |
キーワード | gender-affirming surgery, vaginoplasty gender incongruence transwomen |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-10 |
巻 | 76巻 |
号 | 5号 |
出版者 | Okayama University Medical School |
開始ページ | 597 |
終了ページ | 603 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36352808 |
Web of Science KeyUT | 000884907100014 |
JaLCDOI | 10.18926/AMO/64031 |
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フルテキストURL | 76_5_511.pdf |
著者 | Tomita, Hayato| Kuramochi, Kenji| Fujikawa, Atsuko| Ikeda, Hirotaka| Komita, Midori| Kurihara, Yoshiko| Kobayashi, Yasuyuki| Mimura, Hidefumi| |
抄録 | Iterative reconstruction (IR) improves image quality compared with filtered back projection (FBP). This study investigated the usefulness of model-based IR (forward-projected model-based iterative reconstruction solution [FIRST]) in comparison with FBP and hybrid IR (adaptive iterative dose reduction three-dimensional processing [AIDR 3D]) in low-dose paranasal CT. Twenty-four patients with paranasal sinusitis who underwent standard-dose CT (120 kV) and low-dose CT (100 kV) scanning before and after medical treatment were enrolled. Standard-dose CT scans were reconstructed with FBP (FBP120), and low-dose CT scans with FBP (FBP100), AIDR 3D, and FIRST. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in three anatomical structures and effective doses were compared using Mann–Whitney U test. Two radiologists independently evaluated the visibility of 16 anatomical structures, overall image quality, and artifacts. Effective doses in lowdose CT were significantly reduced compared with those in standard-dose CT (0.24 vs 0.43 mSv, p<0.001). FIRST achieved significantly higher SNR (p<0.01, respectively) and CNR (p<0.001, respectively) of evaluated structures and significant improvement in overall image quality (p<0.001), artifacts (p<0.001), and visibility related to muscles (p<0.05) compared to FBP120, FBP100, and AIDR 3D. FIRST allowed radiation-dose reduction, while maintaining objective and subjective image quality in low-dose paranasal CT. |
キーワード | paranasal sinuses iterative reconstruction dose reduction low dose |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-10 |
巻 | 76巻 |
号 | 5号 |
出版者 | Okayama University Medical School |
開始ページ | 511 |
終了ページ | 517 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36352797 |
Web of Science KeyUT | 000884907100003 |
フルテキストURL | fulltext.pdf |
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著者 | Murata, Atsuo| Doi, Toshihisa| Karwowski, Waldemar| (Life Senior Member, IEEE)| |
キーワード | Haptic interfaces Interference Visualization Graphical user interfaces Target tracking Intelligent vehicles Vehicle safety Speech recognition Automotive safety interference of multiple tasks tactile warning voice command |
発行日 | 2022 |
出版物タイトル | IEEE ACCESS |
巻 | 10巻 |
出版者 | IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC |
開始ページ | 93854 |
終了ページ | 93866 |
ISSN | 2169-3536 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
論文のバージョン | publisher |
DOI | 10.1109/ACCESS.2022.3204045 |
Web of Science KeyUT | 000873916200001 |
関連URL | isVersionOf https://doi.org/10.1109/ACCESS.2022.3204045 |
フルテキストURL | fulltext.pdf |
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著者 | Sukegawa, Shintaro| Tanaka, Futa| Hara, Takeshi| Yoshii, Kazumasa| Yamashita, Katsusuke| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Nagatsuka, Hitoshi| Furuki, Yoshihiko| |
発行日 | 2022-10-08 |
出版物タイトル | Scientific Reports |
巻 | 12巻 |
号 | 1号 |
出版者 | Nature Portfolio |
開始ページ | 16925 |
ISSN | 2045-2322 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s) 2022 |
論文のバージョン | publisher |
PubMed ID | 36209283 |
DOI | 10.1038/s41598-022-21408-9 |
Web of Science KeyUT | 000865228800021 |
関連URL | isVersionOf https://doi.org/10.1038/s41598-022-21408-9 |
フルテキストURL | fulltext20221026-3.pdf |
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著者 | Honda, Yasuko| |
キーワード | Community renewable energy rural community local initiative Japan Agricultural Cooperatives energy cooperative |
備考 | Journal of Asian Rural Studies, 2021, 5(1): 63-77| |
発行日 | 2021-3-26 |
出版物タイトル | Journal of Asian Rural Studies |
巻 | 5巻 |
号 | 1号 |
出版者 | Hasanuddin University and Asian Rural Sociology Association |
開始ページ | 63 |
終了ページ | 77 |
ISSN | 2548-3269 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
論文のバージョン | publisher |
DOI | 10.20956/jars.v5i1.2656 |
関連URL | isVersionOf https://doi.org/10.20956/jars.v5i1.2656 |
フルテキストURL | fulltext.pdf |
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著者 | Togo, Hidetoshi| Asanuma, Kohei| Nishi, Tatsushi| Liu, Ziang| |
キーワード | multi-objective scheduling estimation weighting factors machine learning simulated annealing inverse optimization |
発行日 | 2022-09-21 |
出版物タイトル | Applied Sciences - Basel |
巻 | 12巻 |
号 | 19号 |
出版者 | MDPI |
開始ページ | 9472 |
ISSN | 2076-3417 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2022 by the authors. |
論文のバージョン | publisher |
DOI | 10.3390/app12199472 |
Web of Science KeyUT | 000866634100001 |
関連URL | isVersionOf https://doi.org/10.3390/app12199472 |
JaLCDOI | 10.18926/AMO/63902 |
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フルテキストURL | 76_4_429.pdf |
著者 | Yamadori, Yusuke| Hirao, Tomohiro| Nlandu R. Ngatu| Kanda, Kanae| Syed Mahfuz Al Hasan| Murakami, Akitsu| Mashima, Yukinori| Shirakami, Gotaro| |
抄録 | Blood pressure (BP) often rises before surgery. This study investigated whether BP elevation immediately before surgery was associated with adverse outcomes. Medical records of 11,732 patients (average age: 61 years; male: 47.4%) who underwent non-cardiac elective inpatient surgery under general anesthesia at Kagawa University Hospital between January 2011 and June 2019 were reviewed. Differences between the first BP values measured on the day before surgery and the first BP values in the operating room were defined as Δ systolic BP (ΔSBP) and Δ diastolic BP (ΔDBP). The relationships between ΔSBP/ΔDBP and 30-day mortality, 30-day readmission, and over-the-standard length of hospital stay (OSLOS) were assessed. OSLOS was defined as a hospital stay longer than mean+2 standard deviations and was calculated using the Japanese Diagnosis Procedure Combination data. In univariate analysis, the differences in ΔSBP and ΔDBP between the OSLOS and standard LOS groups were both 2 mmHg. In multivariate logistic regression analysis, only ΔDBP was associated with OSLOS. The adjusted odds ratio (95% confidence interval) for the largest quartile was 1.31 (1.02-1.69) (p<0.05). ΔDBP was associated with OSLOS; however, there may be little need to worry about large ΔSBPs and ΔDBPs in clinical practice. |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-08 |
巻 | 76巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 429 |
終了ページ | 437 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36123158 |
Web of Science KeyUT | 000882167300009 |
JaLCDOI | 10.18926/AMO/63894 |
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フルテキストURL | 76_4_399.pdf |
著者 | Kajiwara, Yukiko| Iwamoto, Takayuki| Zhu, Yidan| Kochi, Mariko| Shien, Tadahiko| Taira, Naruto| Doihara, Hiroyoshi| Toyooka, Shinichi| |
抄録 | According to a recent report, a low Ki67 level after short-term preoperative hormone therapy (post-Ki67) might suggest a more favorable prognosis compared with a high post-Ki67 level in patients with hormone receptorpositive/human epidermal growth factor 2-negative (HR+/HER2−) breast cancer with high levels of Ki67. This study aimed to evaluate the pre-treatment genetic differences between these two patient groups. Forty-five luminal B-like patients were stratified into two groups, namely, a group with high (H→H) and one with low (H→L) Ki67 levels after short-term preoperative aromatase inhibitor (AI) treatment. We compared pre-treatmentgene expression profiles between the two groups. In gene level analysis, there was no significant difference between the two groups by the class comparison test. In pathway analysis, five metabolism-related gene sets were significantly upregulated in the H→L group (p≤0.05). In the search for novel targets, five genes (PARP, BRCA2, FLT4, CDK6, and PDCD1LG2) showed significantly higher expression in the H→H group (p≤0.05). Several metabolism-related pathways were associated with sensitivity to AI. In the future, it will be necessary to seek out new therapeutic strategies for the poor prognostic group with high post-Ki67. |
キーワード | breast cancer short-term hormone therapy gene expression profiling Ki-67 targeted therapy |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2022-08 |
巻 | 76巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 399 |
終了ページ | 408 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 36123154 |
Web of Science KeyUT | 000882167300005 |