検索結果 321 件
| 著者 | 長谷川 芳典| |
|---|---|
| 発行日 | 2006-07-25 |
| 出版物タイトル | 岡山大学文学部紀要 |
| 巻 | 45巻 |
| 資料タイプ | 紀要論文 |
| JaLCDOI | 10.18926/okadai-bun-kiyou/53879 |
| 著者 | Matsuo, Toshihiko| |
|---|---|
| 発行日 | 2015-09-21 |
| 出版物タイトル | SpringerPlus |
| 巻 | 4巻 |
| 資料タイプ | 学術雑誌論文 |
| フルテキストURL | Nature-Shen manuscript for deposit(151002).pdf |
|---|---|
| 著者 | Suga, Michihiro| Akita, Fusamichi| Hirata, Kunio| Ueno, Go| Murakami, Hironori| Nakajima, Yoshiki| Shimizu, Tetsuya| Yamashita, Keitaro| Yamamoto, Masaki| Ago, Hideo| Shen, Jian-Ren| |
| 備考 | The final publication is available at Nature via http://dx.doi.org/10.1038/nature13991| |
| 発行日 | 2015-01-01 |
| 出版物タイトル | Nature |
| 巻 | 517巻 |
| 出版者 | Nature Publishing Group |
| 開始ページ | 99 |
| 終了ページ | 103 |
| ISSN | 0028-0836 |
| NCID | AA00752384 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2015 Michihiro Suga et al.; licensee Macmillan Publishers Limited. |
| 論文のバージョン | author |
| PubMed ID | 25470056 |
| DOI | 10.1038/nature13991 |
| Web of Science KeyUT | 000347178400043 |
| 著者 | 望月 建爾| 甲賀 研一郎| |
|---|---|
| 発行日 | 2015-07-07 |
| 出版物タイトル | Proceedings of the National Academy of Sciences of the United States of America |
| 巻 | 112巻 |
| 号 | 27号 |
| 資料タイプ | 学術雑誌論文 |
| フルテキストURL | K0005201_abstract_review.pdf K0005201_fulltext.pdf |
|---|---|
| 著者 | 難波 真太郎| |
| 発行日 | 2015-06-30 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5201号 |
| 学位授与年月日 | 2015-06-30 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| JaLCDOI | 10.18926/AMO/53560 |
|---|---|
| フルテキストURL | 69_4_237.pdf |
| 著者 | Nanba, Shintarou| Ikeda, Fusao| Fujioka, Shin-ichi| Araki, Yasuyuki| Takaguchi, Kouichi| Hashimoto, Noriaki| Seki, Hiroyuki| Takaki, Akinobu| Iwasaki, Yoshiaki| Yamamoto, Kazuhide| |
| 抄録 | The effectiveness of extending treatment duration as response guided therapy was previously reported for chronic hepatitis C (CHC) genotype 1, but is still controversial for genotype 2. The present study is a retrospective cohort study to investigate the effectiveness of extending treatment duration in therapy with pegylated interferon and ribavirin for patients with CHC genotype 2 by focusing on the timing at which patients obtained undetectable HCV RNA. A total of 306 patients who obtained undetectable HCV RNA by week 24 of treatment and completed 24 weeks of treatment were enrolled. Rapid virological response (RVR) to standard therapy was achieved by 122 patients (51ｵ), and 89ｵ of them obtained sustained virological response (SVR), while 69ｵ of non-RVR patients achieved SVR. Non-RVR patients with undetectable HCV RNA at week 8, and insufficient adherence＜80ｵ pegylated interferon and ribavirin during the first 24 weeks, significantly improved their SVR rate by extended therapy. Among patients receiving extended therapy, drug adherences did not differ between SVR and non-SVR patients, indicating that extending treatment duration might compensate for insufficient antiviral effects due to insufficient drug adherences. This finding might be useful in creating a guideline for extending treatment duration for patients with CHC genotype 2. |
| キーワード | hepatitis C virus interferon genotype 2 response-guided therapy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-08 |
| 巻 | 69巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 237 |
| 終了ページ | 244 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26289915 |
| Web of Science KeyUT | 000365519100007 |
| フルテキストURL | K0005173_abstract_review.pdf K0005173_fulltext.pdf |
|---|---|
| 著者 | GALABADA RALALAGE RUKMALI RUWANTHIKA ATHURUPANA| |
| 発行日 | 2015-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5173号 |
| 学位授与年月日 | 2015-03-25 |
| 学位・専攻分野 | 博士（学術） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| JaLCDOI | 10.18926/AMO/53020 |
|---|---|
| フルテキストURL | 68_6_317.pdf |
| 著者 | Kasahara, Kyosuke| Miyoshi, Ko| Murakami, Shinki| Miyazaki, Ikuko| Asanuma, Masato| |
| 抄録 | In vertebrates, almost all somatic cells extend a single immotile cilium, referred to as a primary cilium. Increasing evidence suggests that primary cilia serve as cellular antennae in many types of tissues by sensing chemical or mechanical stimuli in the milieu surrounding the cells. In rodents an antibody to adenylyl cyclase 3 (AC3) has been widely used to label the primary cilia of neurons in vivo by immunostaining, whereas the lack of markers for the primary cilia of astrocytes has made it difficult to observe astrocytic primary cilia in vivo. Here, we obtained a visualization of astrocytic primary cilia in the mouse brain. In the somatosensory cortex, a large portion of neurons and astrocytes at postnatal day 10 (P10), and of neurons at P56 had AC3-positive primary cilia, whereas only approx. one-half of the astrocytes in the P56 mice carried primary cilia weakly positive for AC3. In contrast, the majority of astrocytes had ADP-ribosylation factor-like protein 13B (Arl13b)-positive primary cilia in the somatosensory cortex and other brain regions of P56 mice. The lengths of astrocytic primary cilia positive for Arl13b varied among the brain regions. Our data indicate that Arl13b is a noteworthy marker of astrocytic primary cilia in the brain. |
| キーワード | primary cilia astrocyte ADP-ribosylation factor-like protein 13B |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-12 |
| 巻 | 68巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 317 |
| 終了ページ | 322 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 25519025 |
| Web of Science KeyUT | 000346882200001 |
| 著者 | Nishikawa, Hitoshi| Oto, Takahiro| Otani, Shinji| Harada, Masaaki| Iga, Norichika| Miyoshi, Kentaroh| Miyoshi, Shinichiro| |
|---|---|
| 発行日 | 2013-12 |
| 出版物タイトル | The Journal of Thoracic and Cardiovascular Surgery |
| 巻 | 146巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Kongprakhon, Phinyarat| Cuesta-Marcos, Alfonso| Hayes, Patrick M.| Richardson, Kelley L.| Sirithunya, Pattama| Sato, Kazuhiro| Steffenson, Brian| Toojinda, Theerayuth| |
|---|---|
| 発行日 | 2009-12 |
| 出版物タイトル | Breeding Science |
| 巻 | 59巻 |
| 号 | 4号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Yamagishi, Hiroyuki| Watanabe, Kohtaro| Kametaka, Yoshinori| |
|---|---|
| 発行日 | 2014-01 |
| 出版物タイトル | Mathematical Journal of Okayama University |
| 巻 | 56巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/mjou/52074 |
| JaLCDOI | 10.18926/AMO/52008 |
|---|---|
| フルテキストURL | 67_6_351.pdf |
| 著者 | Yokoyama, Yusuke| Abe, Nobuhiro| Fujiwara, Kazuo| Suzuki, Masahiko| Nakajima, Yoshikazu| Sugita, Naohiko| Mitsuishi, Mamoru| Nakashima, Yoshio| Ozaki, Toshifumi| |
| 抄録 | A computer-assisted navigation system to be used for total knee arthroplasties (TKAs) was reported to improve the accuracy of bone resection and result in precise implant placement, but the concomitant surgical invasion and time consumption are clinical problems. We developed a computed tomography (CT)-based navigation system (NNS) to be used for minimally invasive TKA. It requires only the reference points from a small limited area of the medial femoral condyle and proximal tibia through a skin incision to obtain optical images. Here we evaluated the usefulness and accuracy of the NNS in comparison with the commercially available BrainLAB image-free navigation system (BLS). In a clinical experiment, the registration times obtained with the NNS tended to be shorter than those obtained with the BLS, but not significantly so. The NNS group tended to be in the extended position in the sagittal plane of the distal femur within 3 degrees, and the BLS group showed rather flexed deviation in the sagittal plane of the anterior femur. |
| キーワード | total knee arthroplasty navigation system minimally invasive surgery |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-12 |
| 巻 | 67巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 351 |
| 終了ページ | 358 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24356719 |
| Web of Science KeyUT | 000328915700003 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/52515 |
| 著者 | Tomita, Nao| Hattori, Takako| Itoh, Shinsuke| Aoyama, Eriko| Yao, Mayumi| Yamashiro, Takashi| Takigawa, Masaharu| |
|---|---|
| 発行日 | 2013-03-28 |
| 出版物タイトル | PLoS ONE |
| 巻 | 8巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/50414 |
|---|---|
| フルテキストURL | 67_3_197.pdf |
| 著者 | Yasuhara, Takao| Takahashi, Yuichi| Kumamoto, Shinji| Nakahara, Masayuki| Yoneda, Kotaro| Niimura, Tatsuomi| Tanoue, Takashi| Kusumegi, Akira| Sennari, Takashi| Hijikata, Yasukazu| Manabe, Hiroaki| Miyoshi, Yasuyuki| Date, Isao| Ogawa, Koichi| Nishida, Kenki| |
| 抄録 | Some cases with lumbar degenerative diseases require multi-level fusion surgeries. At our institute, 27 and 4 procedures of 3- and 4-level fusion were performed out of a total 672 posterior lumbar interfusions (PLIFs) on patients with lumbar degenerative disease from 2005 to 2010. We present 2 osteoporotic patients who developed proximal vertebral body fracture after 4-level fusion. Both cases presented with gait disability for leg pain by degenerative lumbar scoliosis and canal stenosis at the levels of L1/2-4/5. After 4-level fusion using L1 as the upper instrumented vertebra, proximal vertebral body fractures were found along with the right pedicle fractures of L1 in both cases. One of these patients, aged 82 years, was treated as an outpatient using a hard corset for 24 months, but the fractures were exacerbated over time. In the other patient, posterolateral fusion was extended from Th10 to L5. Both patients can walk alone and have been thoroughly followed up. In both cases, the fracture of the right L1 pedicle might be related to the subsequent fractures and fusion failure. In consideration of multi-level fusion, L1 should be avoided as an upper instrumented vertebra to prevent junctional kyphosis, especially in cases with osteoporosis and flat back posture. |
| キーワード | degenerative lumbar scoliosis osteoporosis pedicle fracture posterior lumbar interbody fusion vertebral body fracture |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-06 |
| 巻 | 67巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 197 |
| 終了ページ | 202 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23804144 |
| Web of Science KeyUT | 000320747900010 |
| JaLCDOI | 10.18926/AMO/50412 |
|---|---|
| フルテキストURL | 67_3_185.pdf |
| 著者 | Misawa, Haruo| Tanaka, Masato| Sugimoto, Yoshihisa| Koshimune, Kouichiro| Ozaki, Toshifumi| |
| 抄録 | Cervical misalignment after upper cervical fusion including the occipital bone may cause trismus or dysphagia, because the occipito-atlanto joint is associated with most of the flex and extended motion of the cervical spine. There are no reports of dysphagia and trismus after C1-2 fusion. The purpose of this paper is to demonstrate the potential risk of dysphagia and trismus even after upper cervical short fusion without the occipital bone. The patient was a 69-year-old man with myelopathy caused by os odontoideum and Klippel-Feil syndrome, who developed dysphagia and trismus immediately after C1-2 fusion and C3-6 laminoplasty. Radiographs and CT revealed that his neck posture was extended, but his symptoms still existed a week after surgery. The fixation angle was hyperextended 12 days after the first surgery. His symptoms disappeared immediately after revision surgery. The fixation in the neck-flexed position is thought to be the main cause of the patientʼs post-operative dysphagia and trismus. Dysphagia and trismus may occur even after short upper cervical fusion without the occipital bone or cervical fusion in the neck-extended position. The pre-operative cervical alignment and range of motion of each segment should be thoroughly evaluated. |
| キーワード | dysphagia trismus os odontoid Klippel-Feil syndrome atlantoaxial posterior fusion |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-06 |
| 巻 | 67巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 185 |
| 終了ページ | 190 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23804142 |
| Web of Science KeyUT | 000320747900008 |
| 著者 | 竹内 孔一| 竹内 奈央| 石原 靖弘| |
|---|---|
| 発行日 | 2012-07-19 |
| 出版物タイトル | 情報処理学会研究報告. 自然言語処理研究会報告 |
| 巻 | 2012-NL-207巻 |
| 号 | 15号 |
| 資料タイプ | テクニカルレポート |
| JaLCDOI | 10.18926/AMO/49671 |
|---|---|
| フルテキストURL | 67_2_117.pdf |
| 著者 | Sadamori, Hiroshi| Yagi, Takahito| Shinoura, Susumu| Umeda, Yuzo| Yoshida, Ryuichi| Sato, Daisuke| Nobuoka, Daisuke| Utsumi, Masashi| Fujiwara, Toshiyoshi| |
| 抄録 | We present a case of living donor liver transplantation to a 3-year disease-free survivor of liver resection for hepatocellular carcinoma (HCC) with major portal vein invasion. A 48-year-old man had HCC in the right lobe with a portal venous tumor thrombus extending into the left portal vein. An extended right lobectomy with thrombectomy was performed to remove the thrombus. Three years after liver resection, the patient experienced liver failure, with massive ascites and jaundice due to the formation of a thrombus in the main and left portal veins. During the 3 years after liver resection, no metastasis or recurrence of HCC had been detected, and tumor markers had been within normal ranges. The portal venous thrombus did not show any arterial enhancement under contrast-enhanced computed tomography, suggesting that the co-existence of any HCC component in the portal venous thrombus may have been negative. Based on these findings, living donor liver transplantation was performed using a right lobe graft from the patientʼs son. The patient is alive at 87 months after the transplantation, with no evidence of HCC recurrence. |
| キーワード | living donor liver transplantation hepatocellular carcinoma portal vein invasion liver resection |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2013-04 |
| 巻 | 67巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 117 |
| 終了ページ | 121 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2013 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 23603929 |
| Web of Science KeyUT | 000317801700007 |
| 著者 | 鵜殿 平一郎| |
|---|---|
| 発行日 | 2013-04-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 125巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/49297 |
|---|---|
| フルテキストURL | bhe_008_151_162.pdf |
| 著者 | Nakamura, Ian| |
| 抄録 | Surviving, thriving, and evolving followed by further noticing, reflecting, and acting are some of the stages a teacher-researcher goes through before, during, and after the study leave experience. Having the opportunity to literally remove oneself from the daily concerns, routines, and habits entrenched in one’s local institutional context for an extended period of time（ e.g., six months） is an experience like no other. Blood donation campaigns call giving blood ‘a gift that keeps on giving’. While the majority of people in our profession do carry on with their work quite well without ever going on a study leave （or donating blood）, an important revelation that I have had is: a study leave is also ‘a gift that keeps on giving’. |
| キーワード | study leave professional development reflective learning |
| 出版物タイトル | 大学教育研究紀要 |
| 発行日 | 2012-12-31 |
| 巻 | 8巻 |
| 開始ページ | 151 |
| 終了ページ | 162 |
| ISSN | 1881-5952 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120005232354 |
| JaLCDOI | 10.18926/ESR/49212 |
|---|---|
| タイトル（別表記） | A case study on persistent appearance of the ensemble of precipitation bands in the warm sector of the Baiu front in the western Japan around 19 June 2001 |
| フルテキストURL | esr_019_1_039_050.pdf |
| 著者 | 合田 泰弘| 加藤 内藏進| 塚本 修| |
| 抄録 | A case study on persistent appearance of the ensemble of precipitation bands in the warm sector of the Baiu front in Kyushu District, the western part of Japan around 19 June 2001 was performed based on the operational observational data. Around 00UTC (09JST) 19 June when the Baiu front on the surface weather map was still located about a few 100kms to the north of Kyushu, the number and the total area of the meso-β or γ-scale line-shaped precipitation bands increased around Kyushu rapidly. These precipitation bands had been sustained there and gradually gathered each other to change into the Baiu frontal precipitation zone extending from the northern Kyushu to Seto-Naikai (Seto Inland Sea) around 09UTC (18JST) 19 June (the intense rainfall zone was still located in the warm sector of the Baiu front). Until ~09UTC (18JST) 19 June, the moist air flow with the latently unstable stratification had been sustained around Kyushu corresponding to the low-level southerly wind toward the surface Baiu front to the north of Kyushu. This large-scale situation would contribute greatly to the maintenance of the ensemble of the line-shaped precipitation bands in the warm sector of the Baiu front. |
| キーワード | ensemble of line-shaped precipitation bands precipitation in the warm sector of the Baiu front Baiu fronal rainfall |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2012-12-26 |
| 巻 | 19巻 |
| 号 | 1号 |
| 開始ページ | 39 |
| 終了ページ | 50 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2012 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120005232330 |