恙虫病病毒の生物学的性状に関する研究 第2編 恙虫病病毒の薬剤に対する抵抗性の吟味

The author studied the effect of various disinfectants on the crude and purified materials of R. tsutsugamushi; after the contact with disinfectants for a certain time, the materials were inoculated into mice, and the decrease of the virulence was studied. The results are summarized as follows: 1) The crude material containing rickettsiae inside cells shows much higher resistance to disinfectants than the purified one containing rickettsiae in a cell-free state and very little protein. 2) Of all the conventional disinfectants such as phenol, formalin, merthiolate, cresol soap and ethyl alcohol, 1.0% phenol and 1.0% formalin are the most effective against R. tsutsugamushi. In the usual application concentration, however, 70% ethyl alcohol shows the strongest disinfective action.