検索結果 28219 件
| JaLCDOI | 10.18926/40162 |
|---|---|
| タイトル（別表記） | Isotopic study of Hot Springs in Japan, I Techniques for oxygen isotopic analysis of spring water |
| フルテキストURL | pitsr_040_033_040.pdf |
| 著者 | 松葉谷 治| 酒井 均| 田中 ひな子| 上村 多鶴恵| |
| 抄録 | The CO(2)-H(2)O isotopic equilibration technique was studied for the routine analyses of the oxygen isotopic ratios of hot spring water. A reaction vessel containing 2 ml of water and 0.16 m mole of tank CO(2) was shaken for 18 hrs. in a constant-temperature bath at 25.0℃ (Figs. 1, 2, and 3), and the CO(2) was analyzed for the oxygen isotopic ratio by a MCKINNEY type mass spectrometer. Several aliquots of 1, 2 and 5 ml from a same water were each analyzed three times by successive equilibration (Table 1). The observed values differ depending on the volume of water but the corrected values by equation (6) indicate excellent agreement, implying the whole processes to be well controlled. The reproducibility of the isotopic analyses is better than ± 0.1‰ (Table 2) in most cases, and the accuracy would not be worse than ± 0.2‰ as demonstrated by the interlaboratory comparison of some standard samples (Table 3). Oxygen isotopic ratios of water from more than 70 hot springs in Japan are presented (Table 5). Although the results will be discussed in the following issues of this series of paper, most hot spring water have the δ(18)O values similar to those of meteoric waters in Japan. However, spring water from Arima Hot Springs, Hyogo-Pref., which has been known by its abnormally high chloride and low sulfate concentrations is of an exceptionally high δ(18)O value. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1971-03-26 |
| 巻 | 40巻 |
| 開始ページ | 33 |
| 終了ページ | 40 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002398154 |
| JaLCDOI | 10.18926/40161 |
|---|---|
| タイトル（別表記） | Studies on the uptake of (75)Se-selenomethionine by the pancreas Attempt to augment by the effects of protocols |
| フルテキストURL | pitsr_040_019_031.pdf |
| 著者 | 得能 恒夫| |
| 抄録 | Since the introduction of the pancreatic scanning using (75)Se-selenomethionine, there has been various protocols proposed to increase the pancreatic uptake of this isotope. In this experiment several protocols; as diets high carbohydrate meal, high protein meal, high fat meal, and as medicaments pancreozymin, secretin and phydroxyphenylsalicylamide (PHPS), were tested for determining the effects on the uptake of (75)Se-selenomethionine by the pancreas and the liver of the dog. The animals given protocols were sacrified at each of a number of selected times to compare P/L ratio on a percentper-gram concentration of (75)Se-selenomethionine and the total organ concentration of (75)Se-selenomethionine in the pancreas and in the liver. A controlled group of animals were fasted for 24-hour and sacrificed at each of same times. On P/L ratio basis it was found that animals with high carbohydrate meal had better ratio than those with no preparation during first 4-hour post administration. However, animals with each of high protein meal. fat meal and PI-IPS had lower ratio than those with no preparation. On the blood concentration, animals with each of high carbohydrate meal and secretin had lower variation of blood concentration than controlled group. Thus, from the results mentioned above, the protocol by high carbohydrate meal is proved to be useful in pancreatic scanning. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1971-03-26 |
| 巻 | 40巻 |
| 開始ページ | 19 |
| 終了ページ | 31 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002398153 |
| JaLCDOI | 10.18926/40160 |
|---|---|
| タイトル（別表記） | Clinical studies on electromyographic changes in rheumatoid arthritis Part III. Effect of radioactive hot spring baths |
| フルテキストURL | pitsr_040_001_017.pdf |
| 著者 | 池上 忠興| |
| 抄録 | The author observed the changes in electromyographic patterns of 14 patients with rheumatoid arthritis (13 cases of classical rheumatoid arthritis and one case of definite rheumatoid arthritis) bathed 2 or 3 times daily in hot spring water at Misasa Spa, at a temperature of 40±1℃, 5-10 minutes. The electromyographic examination was performed on the biceps brachii, opponens pollicis and the abductor pollicis brevis. Intramuscular temperature was measured in the deltoid muscle. The results were as follows. 1) The intramuscular temperature in cases of rheumatoid arthritis did not deviate from normal subjects. 2) After the general spring bathing the intramuscular temperature increased about 1℃ and it had no difference between the patients with rheumatoid arthritis and normal subjects. 3) With increasing intramuscular temperature by the general spring bathing in cases of active rheumatoid arthritis the mean potential amplitude decreased and the mean potential duration increased. 4) With increasing intramuscular temperature by the general spring bathing in cases of inactive rheumatiod arthritis the mean amplitude increased and the mean duration decreased. 5) The patterns of potential duration and amplitude before and after a bath on re-examination, one month after a series of the general spring baths, showed a tendency of reverse of the initial patterns. 6) After two months of a series of the general spring baths, the patterns of electromyographic changes of patients with rheumatoid arthritis following the bathing were similar to the initial patterns. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1971-03-26 |
| 巻 | 40巻 |
| 開始ページ | 1 |
| 終了ページ | 17 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002398152 |
| 著者 | 岡山大学温泉研究所| |
|---|---|
| 発行日 | 1971-03-26 |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 巻 | 40巻 |
| 資料タイプ | その他 |
| 著者 | 岡山大学温泉研究所| |
|---|---|
| 発行日 | 1971-03-26 |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 巻 | 40巻 |
| 資料タイプ | その他 |
| 著者 | 岡山大学温泉研究所| |
|---|---|
| 発行日 | 1972-03-25 |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 巻 | 41巻 |
| 資料タイプ | その他 |
| 著者 | 岡山大学温泉研究所| |
|---|---|
| 発行日 | 1972-03-25 |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 巻 | 41巻 |
| 資料タイプ | その他 |
| JaLCDOI | 10.18926/40155 |
|---|---|
| タイトル（別表記） | Esophagus hiatal hernia with special reference to the early stage |
| フルテキストURL | pitsr_041_063_068.pdf |
| 著者 | 野一色 泰晴| 古元 嘉昭| 仲原 泰博| |
| 抄録 | In the aged, hiatal hernia should be recognized as it has developed; it develops progressively. Special attention should be given to the early stage of hiatal hernia from the genetic point of view. Like other organs in the aged, aging changes around a hiatus are inevitable; relaxing of esophageal diaphragmatic ligament and weakening of muscle power of diaphragmatic vertebral part move on with age. After all, valve structure at hiatus, Goubaroff's valve, is so weakened its function and in the stomach, "His angle" is so widened, that the stomach becomes wedge shaped against the hiatus. The more the pressure in the stomach increases, the larger the wedge shapes. Under these conditions, when the abdominal pressure rises by the acts of coughing or defecation, hiatus may be widened and the wedge may be pushed into the hiatus. There are no strong valve and or ligament enough to keep the wedge part of stomach in peritoneal cavity. In the stomach, the pressure of the expelling meal is equal to that of the widening wedge. On the other hand, in the peritoneal cavity, pressure produced by the act of defecation is equal to that of ejecting the wedge through hiatus. These are self-evident from the Pascal's principle. Hiatal hernia is produced under these conditions. We, therefore, should call the attention to the early genetic stage of hiatal hernia. In Japan, hiatal hernia has been recognized when it gets larger and fixes out of the peritoneal cavity. But in the early stage, it also must be noted as hiatal hernia. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1972-03-25 |
| 巻 | 41巻 |
| 開始ページ | 63 |
| 終了ページ | 68 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002398151 |
| JaLCDOI | 10.18926/40154 |
|---|---|
| タイトル（別表記） | Report of a case of severe mechanical joundice -Successfully treated by jejuno-hepatic ducts anastomoses |
| フルテキストURL | 041_057_062.pdf |
| 著者 | 野一色 泰晴| 小竹森 通明| 古元 嘉昭| 仲原 泰博| |
| 抄録 | Jejuno hepatic ducts anastomoses were successfully performed by carefull managements. Because of dense adhesion at hilus of liver, around the gall bladder and choledocus, dissection of common duct, cystic duct, hepatic ducts and even gall bladder was very difficult anatomically. Resecting a inflammatory granulative tumor, including gall bladder, choledocus, lesser omentum and hepatocluodenal ligament en mass, we found that only very short hepatic ducts with inflammatory granulation tissue were remained open. Reconstruction of biliary passages was done using Roux. Y. method with loop jejunum. It needed very carefull procedure to avoid suture failure, ascending infection (cholangitis) and postoperative stenoses at the site of the anastomoses. The anastomoses were performed using atraumatic 3-0 Tefdek ; interrupted and each big bite of duct wall together with surrounding thickend granulative tissue, in order to keep capillary blood supply effective and to minimize the anastomotic trauma which were very important for wound healing. Patient is healthy, enjoying his normal life and his liver function tests are within normal range, 1 1/2 years postoperatively. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1972-03-25 |
| 巻 | 41巻 |
| 開始ページ | 57 |
| 終了ページ | 62 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532304 |
| JaLCDOI | 10.18926/40153 |
|---|---|
| タイトル（別表記） | Absorption of Medium-chain triglyceride (MCT) in isolated intestinal loops of dog and its effect upon the lipids of serum aud adipose tissue |
| フルテキストURL | pitsr_041_049_056.pdf |
| 著者 | 小竹森 通明| |
| 抄録 | The absorption of medium chain triglyceride (MCT) has been investigated with intestinal loop of dog without both bile and pancreatic juce. On optimal state, the average coefficient of fat absorption was 78.1±7.4%. The use of medium chain triglyceride diet for 4 weeks in dogs had some effecton lipids of serum and adipose tissue but minimal change on clinical evidence was found. There was a prompt reduction in the proportion of arachidonic acid and a sustained increase in the proportion of oleic acid and linoleic acid in serum lipid. Analysis on lipids of adipose tissue showed prompt reduction in the proportion of oleic acid and linoleic acid. Neither clinical evidence nor side effect induced with medium chain triglyceride was found. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1972-03-25 |
| 巻 | 41巻 |
| 開始ページ | 49 |
| 終了ページ | 56 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002398150 |
| JaLCDOI | 10.18926/40152 |
|---|---|
| タイトル（別表記） | Studies on chrysotherapy in rheumatoid arthritis, III. Gold determination by the atomic absorption spectrophotometry |
| フルテキストURL | 041_035_048.pdf |
| 著者 | 高橋 和枝| |
| 抄録 | The gold concentration in serum, synovial fluid and urine has been determined using a HITACHI MODEL 207 atomic absorption spectrophotometer. Flow rate of acetylene was setted at 2.0l/min. and lamp current was setted at 8mA. The samples were pretreated by the determination of gold. Serum was diluted with deionized water by two to ten-fold. To O.2ml. of synoival fluid 50units/ml of hyaluronidase was added and then incubated for 20 minutes at 37℃. This sample was then treated the procedure for serum given previously. Urine was treated using the modification method of Christions procedure. The recovery rates with gold sodium thiomalate in serum, synovial fluid and urine were 99.9%, 102.5% and 93.6% respectively. When gold sodium thiomalate was injected in rabbits, the maximum serum gold level was attained 1 hour after injection and then gradually decreased at about 50% of the maximum level 24 hours after injection. In the observations of changes in the gold levels in the serum of patients with rheumatoid arthritis after injection of gold sodium thiomalate and gold thioglucose, its peak level after gold thioglucose injection tended to be slightly lower as compared with the same amount of gold sodium thiomalate injection. In those patients who had been given 300 mg. or more of gold salt-preparation, one additional injection of 25 mg. of gold salt could attain the gold level of around 200μg/100ml, in serum a week later, and this level was very nearly the same with that after 3-4 days of one additional injection of 1Omg. of gold salt. The amount of gold excreted in the urine varied from patient to patient, and the mean excretion rates of gold sodium thiomalate and gold thioglucose in the urine within 24 hours after intramuscular administralion were 9.8% and 6.5% respectively. The simple, rapid and accurate method for analysis in biological specimens using atomic absorption spectrophotometer would offer one of the excellent measures in the clinical management of patients with rheumatoid arthritis. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1972-03-25 |
| 巻 | 41巻 |
| 開始ページ | 35 |
| 終了ページ | 48 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532302 |
| 著者 | 井上 妙子| 森永 寛| |
|---|---|
| 発行日 | 1972-03-25 |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 巻 | 41巻 |
| 資料タイプ | データ・データベース |
| JaLCDOI | 10.18926/40150 |
|---|---|
| タイトル（別表記） | On the measurement of oxygen and carbon isotopic ratios of carbonates |
| フルテキストURL | pitsr_041_009_012.pdf |
| 著者 | 渡辺 洵| 松葉谷 治| |
| 抄録 | Oxygen and carbon isotopic ratios of two working standards of our laboratory and three other standards were measured by McCrea's technique and the new McKINNEY type mass spectrometer in this Institute. The reproducibility of δ(13)C measurement is about ±0.2‰. Some systematic differences in δ(18)O values were observed among the three measurements in Apr.-May, July, and Aug., 1971. Because these systematic differences are supposed to be caused by the imperfection in the processes of decomposition of carbonates by phosphoric acid, the reproducibility of δ(18)O measurement may be ±O.2‰ in most cases. The calibrations of our working standard, CK-13, against the PDB standard were carried out on the assumption that δ(18)O and δ(13)C of CK-13 are -1.75‰ and +O.54‰ relative to PDB, respectively. The accuracy of these calibrations is about ±O.2‰ as shown by the interlaboratory comparison of some standards (Table 3). The δ(18)O values of the two working standards relative to PDB are independently recalculated relative to SMOW based on the two assumptions (Table 4). One of which is that a standard water MSA-2 is -8.20‰ relative to SMOW, and the other is that the δ(18)O of CK-13 is -1.75‰ relative to PDB. The results of both calculations agree within 0.4‰. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1972-03-25 |
| 巻 | 41巻 |
| 開始ページ | 9 |
| 終了ページ | 12 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002398149 |
| JaLCDOI | 10.18926/40149 |
|---|---|
| タイトル（別表記） | A subsequent report on the new McKinney type mass spectrometer in the Institute for Thermal Spring Research, Okayama University |
| フルテキストURL | pitsr_041_003_007.pdf |
| 著者 | 松葉谷 治| |
| 抄録 | Since the installation in April 1970, the McKinney type mass spectrometer has maintained a good condition and about 5000 isotopic analyses of oxygen, carbon and sulfer has been cerried out so far. The ion source filament was changed to spiral one from single wire. Consequently three times sensitivity and the longer life of filament were obtained. Gradual changes in the ratio of potential divider (β) and the sensitivity (|△ E(0)(2)|/E(0)(1)) for the difference of β have been observed (Table 1). Because these changes are opposite in trend but similar in degree, it is supposed that these changes are caused by decrease of feed-back resister value in the balancing system. Although there remain some problems in the corrections for the difference in observed isotopic tatio between two cases that a same CO(2) is fed to ion source from the ST side of inlet system on the one hand and from the X side on the another, the reproducibility of the measurement of isotopic ratio for long period is about ±O.1‰ (Table 2, Fig. 1). δ(18)O values of standard waters, MSA-1 and MSA-2, measured during a period from May to Dec. 1970 and in Sep. 1971 yielded good agreements implying the reproducibility of the measurement to be constant (Table 3). Both calculated δ(18)O values relative to a given sample based on each observed δ(18)O value relative to two different samples agreed each other. It is concluded that the linearity of observed a-value holds over a range of 30‰ (Table 4). |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1972-03-25 |
| 巻 | 41巻 |
| 開始ページ | 3 |
| 終了ページ | 7 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002398147 |
| JaLCDOI | 10.18926/40148 |
|---|---|
| タイトル（別表記） | The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique |
| フルテキストURL | pitsr_041_001_002.pdf |
| 著者 | 松葉谷 治| |
| 抄録 | The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique was studied. In this study, a new type of reaction vessel was used (Fig. 1). The reaction time for equilibration using this new reaction vessel was nearly equal to that in the previous study (Fig. 2). The oxygen isotopic ratios of each two samples of pH 2, 4, 7, 8, 9, and 10 were measured. There is no significant difference between the observed δ(18)O values of these samples (Table 1). Therefore it is concluded that the effect of pH of water needs not to be taken into account on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1972-03-25 |
| 巻 | 41巻 |
| 開始ページ | 1 |
| 終了ページ | 2 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120002398148 |
| 著者 | 岡山大学温泉研究所| |
|---|---|
| 発行日 | 1972-03-25 |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 巻 | 41巻 |
| 資料タイプ | その他 |
| 著者 | 岡山大学温泉研究所| |
|---|---|
| 発行日 | 1972-03-25 |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 巻 | 41巻 |
| 資料タイプ | その他 |
| 著者 | 岡山大学温泉研究所| |
|---|---|
| 発行日 | 1973-03-25 |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 巻 | 42巻 |
| 資料タイプ | その他 |
| 著者 | 岡山大学温泉研究所| |
|---|---|
| 発行日 | 1973-03-25 |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 巻 | 42巻 |
| 資料タイプ | その他 |
| JaLCDOI | 10.18926/40143 |
|---|---|
| タイトル（別表記） | Rheumatoid arthritis and Sjögren's syndrome |
| フルテキストURL | 042_031_045.pdf |
| 著者 | 市川 幸延| |
| 抄録 | 1. Parotid Sialography Parotid sialograms were investigated in 29 patients with classical or definite RA according to the criteria of the American Rheumatism Association (one of whom had scleroderma), 5 patients with SLE (according to the Dubois's criteria, three were definite, one probable and another possible SLE), 3 patients with other autoimmune diseases (Hashimoto's thyroiditis, colitis ulcerosa and undiagnosed collagen disease), 3 patients with polyarthralgia and 10 patients with nonautoimmune diseases. Sialographic technique was performed by modified Rubin's Method using contrast medium Conray-400. Sialectasis which is pathognomonic of Sjögren's syndrome (SS) alone was observed in 6 patients with RA (20.7%) (3 punctate and 3 globular patterns) and 2 patients with SLE (one punctate and another globular pattern). Retention of the contrast medium in the duct for at least 5 minutes after the injection was observed in patients with RA, one patient with SLE and one patient with colitis ulcerosa. Sial ectasis and retention almost always existed together, and were observed in patients from young to older one. Although dilatation of the Stensen's duct and subalveolar dissection also existed together, they were observed in only older patients. It appeared that the former is the specific findings of SS and the latter is the non-specific findings according to the aging. Dry mouth was complained in 7 sialectasis (87.5%), 3 subalveolar dissection (60.0%), 10 retention (62.5%) and 9 normal sialogram (37.5%). Salivary hyposecretion (less than 10 ml/10min) was observed in 4 sialectasis (50%), one subalveolar dissection (20%), 6 dilatation of the Stensen's duct (37.5%), 5 retention (45.5%) and one normal sialogram (4.2%). These results show that sialectasis and retention are well correlated with salivary hyposecretion, but dry mouth is not so diagnostic in SS. Two patients with SLE had sialectasis were young women and showed normal salivary and lacrimal secretion. These cases may be supported by Heaton's hypothesis that SS is a benign and chronic form of SLE, or thay may be a subclinical state of SS. 2. Schirmer test Sixty seven patients (36RA, 6SLE, 3 other autoimmune diseases, 3 polyarthralgia and 19 non-autoimmune diseases) were examined by Schirmer test. Besides lacrimal hyposecretion was observed in RA and other autoimmune diseases, it began in younger age. These results show that autoimmune diseases have a sicca element in themselves. Compared with the results of sialography, Schirmer test was not correlated with sialectasis and retention. Dry eye was complained in only 4 patients (13.3%) with lacrimal hyposecretion (less than 10mm/5min) and all patients with dry eye had keratoconjunctivitis sicca (KCS). Dry eye is more diagnostic than Schirmer test. 3. Corneal staining by 1% rose bengal solution Twenty five patients with RA or SLE were examned corneal staining (Holm's type A) was observed in 5 patients with RA (20%). Staining of the medial and lateral bulbar conjunctiva (Holm's type B and C) were observed in 6 patients with RA (24%) and one patient with SLE. Nine patients with positive staining (type A, B and C) (75%) showed lacrimal hyposecretion. Dry eye was complained in 4 patients with type A staining (80%), but no patient with type B and C complained dry eye. Dry eye appears to be specific for the diagnosis of SS as sialectasis on the sialogram. 4. Salivary secretion All amount of saliva was collected during ten minutes chewing two pieces of gum. All of 21 patients with non-autoimmune diseases showed more than 10 ml/10min, and slight degree of salivary hyposecretion was observed with aging. Nine patients with RA (25.7%) showed salivary hyposecretion (less than 10ml/10min), besides it began in younger age. It was also observed in patients with other autoimmune diseases. Only 36.4% patients with salivary hyposecretion showed sialectasis on the sialogram. It can be supposed that patients with sialectasis and good salivary secretion are subclinical states of SS, and that this state is depends on the compensative function of the glands. Therefore, it is impossible to suppose the salivary dysfunction from the complaints of patients alone. It is required that saliva must be analysed not only quantitativly but also qualitativly (such as RA factor, complement and lysozome). Dry mouth was not only complained in 9 patients who showed salivary hyposecretion (81.8%). but in 10 patients showed normal secretion (50%). Dry mouth appears to be less specific for the diagnosis of SS than dry eye. 5. Diagnosis of SS Vanslow's criteria of SS was modified as follows. (1) Major : ① Sialectasis or salivary gland enlargement ② Positive corneal staining (type A) ③ Classical or definite RA (according to the criteria of the ARA) (2) Minor : ① Arthritis ② History ot salivary gland swelling ③ Dry mouth or salivary hyposecretion (less than 10ml/10min) ④ Dry eye or positive Schirmer test (less than 10mm/5min). Three major was diagnosed as definite, 2 major as probable and one major with one or more minor as possible SS. Of 35 patients with RA, definite (8.6%), probable (17.1%) and possible SS (54.3%) were obserevd. Two of SLE (33.3%) were possible SS. One patients with undiagnosed collagen disease was possible SS. Clinically, definite and probable SS may be diagnosed as Sjögren's syndrome. Two possible SS with SLE may be supporsed as subclinical states of SS who do not yet exhibite full criteria. Compared with the clinical and laboratory findings of these definite, probable and possible SS with RA, it was supporsed that positive antinuclear factor or positive LE cells in RA patients almost always represents SS, drug allergy, especially to gold therapy may be a manifestation of SS. Hypergammaglobulinemia, extreme elevation of erythrocyte sedimentation rate, struma, lymphnode enlargement in RA patients must be suspected of SS. Although one possible SS with SLE and one probable SS with RA showed positive ANF (peripheral pattern), it is impossible to differentiate SS from SLE by ANF alone. Because Suzuki et al. reported that 15.4% of SS had showed positive ANF (peripheral pattern). Examinations of salivary glands including sialography must be performed in patients with SLE in the future. To detect a subclinical SS, sialography and corneal staining must be performed even in patients with no sicca symptom, because of the compensatory functions of salivary and lacrimal glands. |
| 出版物タイトル | 岡山大学温泉研究所報告 |
| 発行日 | 1973-03-25 |
| 巻 | 42巻 |
| 開始ページ | 31 |
| 終了ページ | 45 |
| ISSN | 0369-7142 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 40017532309 |