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タイトル(別表記) A case of laparoscopic and endoscopic cooperative surgery for sigmoidovesical fistula
フルテキストURL 127_123.pdf
著者 加藤 大| 大石 正博| 小寺 正人| 山村 方夫| 池田 秀明| 水野 憲治| 谷 悠真| 山下 裕| 早田 俊司| 倉繁 拓志| 西山 康弘| 西川 大祐|
抄録 We performed laparoscopic and endoscopic cooperative surgery (LECS) for partial colectomy with partial cystectomy in an 80-year-old woman with sigmoidovesical fistula secondary to sigmoid diverticulitis. LECS was designed for local resection of the stomach for gastric submucosal tumors using the endoscopic submucosal dissection (ESD) technique. While conventional open abdominal surgery is very invasive, LECS has enabled surgeons to perform minimally invasive surgery. Although there have been no reported cases in which the bladder was laparoscopically resected after sigmoidovesical fistula division, we were able to safely resect the fistula and preserve the urethral opening by performing laparoscopic and cystoscopic cooperative surgery. There are no previously reported cases in which LECS was performed for partial sigmoidectomy and partial cystectomy ; therefore, we report this as a valuable case, with a review of the literature. We hope that further studies involving more patients will lead to the establishment of this procedure.
キーワード 結腸膀胱瘻(sigmoidovesical fistula) 腹腔鏡内視鏡合同手術(laparoscopic and endoscopic cooperative surgery(LECS))
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
巻 127巻
号 2号
開始ページ 123
終了ページ 126
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.123
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.123
NAID 130005096254
タイトル(別表記) Successful laparoscopic resection of a cecal tumor in a 95-year-old man
フルテキストURL 127_117.pdf
著者 渡邉 彩子| 稲田 涼| 永坂 岳司| 八木 朝彦| 松本 聖| 戸嶋 俊明| 菊池 覚次| 黒田 新士| 近藤 喜太| 母里 淑子| 岸本 浩行| 藤原 俊義|
抄録 We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials (RCTs) revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients.
キーワード 超高齢者(extremely elderly patient) 大腸癌(colorectal cancer) 腹腔鏡手術(laparoscopic surgery)
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
巻 127巻
号 2号
開始ページ 117
終了ページ 121
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.117
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.117
NAID 130005096253
タイトル(別表記) Peritoneal dialysis update
フルテキストURL 127_111.pdf
著者 杉山 斉|
キーワード 持続携行式腹膜透析(CAPD) 自動腹膜透析(APD) SMAP法 尿素Kt/V 腹膜平衡試験(peritoneal equilibration test:PET)
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
巻 127巻
号 2号
開始ページ 111
終了ページ 115
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.111
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.111
NAID 130005096252
タイトル(別表記) Role of COLXV/XVⅢ gene, Multiplexin, as a basement membrane toolkit
フルテキストURL 127_103.pdf
著者 大橋 俊孝|
キーワード 基底膜 ツールキット XV/XVⅢ型コラーゲン プロテオグリカン ミトコンドリア
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
巻 127巻
号 2号
開始ページ 103
終了ページ 109
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.103
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.103
NAID 130005096251
タイトル(別表記) The 2014 Incentive Award of the Okayama Medical Association in Neuroscience (2014 Niimi Prize)
フルテキストURL 127_99.pdf
著者 中村 絵里|
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
巻 127巻
号 2号
開始ページ 99
終了ページ 101
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.99
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.99
NAID 130005096247
タイトル(別表記) The 2014 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2014 Sunada Prize)
フルテキストURL 127_95.pdf
著者 時岡 浩二|
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
巻 127巻
号 2号
開始ページ 95
終了ページ 97
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.95
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.95
NAID 130005096249
タイトル(別表記) The 2014 Incentive Award of the Okayama Medical Association in Cancer Research (2014 Hayashibara Prize and Yamada Prize)
フルテキストURL 127_91.pdf
著者 矢野 修也|
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
巻 127巻
号 2号
開始ページ 91
終了ページ 94
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.91
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.91
NAID 130005096248
タイトル(別表記) The 2014 Incentive Award of the Okayama Medical Association in General Medical Science (2014 Yuuki Prize)
フルテキストURL 127_87.pdf
著者 大久保 奈々子|
出版物タイトル 岡山医学会雑誌
発行日 2015-08-03
巻 127巻
号 2号
開始ページ 87
終了ページ 90
ISSN 0030-1558
関連URL isVersionOf https://doi.org/10.4044/joma.127.87
言語 日本語
著作権者 Copyright (c) 2015 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.127.87
NAID 130005096250
著者 座間味 義人| 小山 敏広| 合葉 哲也| 天野 学| 安藤 哲信| 倉田 なおみ| 名和 秀起| 名倉 弘哲| 北村 佳久| 千堂 年昭|
発行日 2014
出版物タイトル 静脈経腸栄養
巻 29巻
号 4号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/53526
フルテキストURL 69_3_183.pdf
著者 Haruma, Tomoko| Ogawa, Chikako| Nishida, Takeshi| Kusumoto, Tomoyuki| Nakamura, Keiichiro| Seki, Noriko| Katayama, Takaaki| Hiramatsu, Yuji|
抄録 Pure ovarian choriocarcinoma is an extremely rare malignancy that can be gestational or non-gestational in origin. Silver-Russell syndrome (SRS) is a rare congenital developmental disorder characterized by pre- and postnatal growth failure, relative macrocephaly, a triangular face, hemihypotrophy, and fifth-finger clinodactyly. We report a rare case of pure ovarian choriocarcinoma occurring in a 19-year-old woman with SRS. Following surgery, multiple chemotherapy courses were effective and she was free of disease at the 10-month follow-up.
キーワード choriocarcinoma ovary Silver-Russell syndrome
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2015-06
巻 69巻
号 3号
出版者 Okayama University Medical School
開始ページ 183
終了ページ 188
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26101195
Web of Science KeyUT 000356903000008
JaLCDOI 10.18926/AMO/53525
フルテキストURL 69_3_177.pdf
著者 Hoshijima, Mitsuhiro| Honjo, Tadashi| Moritani, Norifumi| Iida, Seiji| Yamashiro, Takashi| Kamioka, Hiroshi|
抄録 This article reports the case of a 44-year-old male with skeletal Class III, Angle Class III malocclusion and unilateral crossbite with concerns about obstructive sleep apnea syndrome (OSAS), esthetics and functional problems. To correct the skeletal deformities, the maxilla was anteriorly repositioned by employing LeFort I osteotomy following pre-surgical orthodontic treatment, because a mandibular setback might induce disordered breathing and cause OSAS. After active treatment for 13 months, satisfactory occlusion was achieved and an acceptable facial and oral profile was obtained. In addition, the apnea hypopnea index (AHI) decreased from 18.8 preoperatively to 10.6 postoperatively. Furthermore, after a follow-up period of 7 months, the AHI again significantly decreased from 10.6 to 6.2. In conclusion, surgical advancement of the maxilla using LeFort I osteotomy has proven to be useful in patients with this kind of skeletal malocclusion, while preventing a worsening of the OSAS.
キーワード LeFort I osteotomy maxillary advancement unilateral crossbite obstructive sleep apnea syndrome
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2015-06
巻 69巻
号 3号
出版者 Okayama University Medical School
開始ページ 177
終了ページ 182
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26101194
Web of Science KeyUT 000356903000007
JaLCDOI 10.18926/AMO/53524
フルテキストURL 69_3_173.pdf
著者 Shirakawa, Yasuhiro| Noma, Kazuhiro| Ohara, Toshiaki| Kashima, Hajime| Maeda, Naoaki| Tanabe, Shunsuke| Kagawa, Shunsuke| Fujiwara, Toshiyoshi|
抄録 A chyle leak can occur as a complication after neck or chest surgery. Such a leak prolongs the hospital stay and is sometimes life-threatening. The treatment options are conservative management, interventional radiologic embolization, and surgery. Thoracoscopic ligation of the thoracic duct has emerged as a promising and definitive treatment. The case of a 65-year-old Japanese male patient with a rare congenital right aortic arch (typeⅢB1 of Edwardʼs classification) and a severe chyle leak that occurred after a total pharyngolaryngo-esophagectomy (TPLE) is described. The chyle leak was successfully managed by thoracoscopic ligation of the thoracic duct via a left-side approach with the patient in the prone position.
キーワード chyle leak thoracic duct thoracoscopy prone position
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2015-06
巻 69巻
号 3号
出版者 Okayama University Medical School
開始ページ 173
終了ページ 176
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26101193
Web of Science KeyUT 000356903000006
JaLCDOI 10.18926/AMO/53523
フルテキストURL 69_3_165.pdf
著者 Sarai, Takaaki| Tokumoto, Akihiro|
抄録 Fall accidents are a common cause of femoral fracture in the elderly. The greater trochanter of the femur is often subjected to impact loading by a sideways fall, and thus it is worth studying the impulsive stress waves propagating in the femur. In this study, the impulsive stress was analyzed by the dynamic finite element method using a 3-dimensional model of the femur, and the influence of the fall configuration on the stress was discussed. The stress was concentrated around the femoral neck during the propagation of the stress wave, and the tensile maximum principal stress changed into compressive minimum principle stress on the anterior and medial sides of the neck. On the other hand, the compressive minimum principal stress changed into tensile maximum principle stress on the lateral side of the neck. The largest maximum principal stress during the impact loading was always larger in the neck than in the impact region. The largest absolute value of the minimum principal stress was found in the neck or the impact region depending on the fall configuration. The largest absolute values of the maximum and minimum principal stress were nearly equal, indicating that the bone fracture due to the tensile stress may occur around the femoral neck.
キーワード biomechanics sideways fall femoral neck greater trochanter impulsive stress wave
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2015-06
巻 69巻
号 3号
出版者 Okayama University Medical School
開始ページ 165
終了ページ 171
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26101192
Web of Science KeyUT 000356903000005
JaLCDOI 10.18926/AMO/53522
フルテキストURL 69_3_155.pdf
著者 Mikamo, Shoko| Nakatsuka, Mikiya|
抄録 To assess the knowledge and attitudes of pregnant Japanese women regarding non-invasive prenatal testing (NIPT). Between March and June 2013, 557 pregnant women in the Hyogo and Hiroshima Prefectures were surveyed using an anonymous, self-completed questionnaire. A total of 91.9オ respondents (512/557) stated that they “agree” or “conditionally agree” with NIPT implementation in Japan. Approximately 28.5オ of respondents stated that they knew that the accuracy of a positive NIPT result can be affected by motherʼs age and background, while 34.5オ of respondents stated that it was necessary for pregnant women with a positive result to undergo fetal chromosome diagnosis using amniocentesis;both percentages were low. Additionally, 92.3オ of respondents would “like a detailed explanation of the test,” 65.1オ of them would “like psychological support if the NIPT test results came back positive,” and 5.7オ would terminate the pregnancy if the NIPT test results came back positive without undergoing fetal chromosome diagnosis via amniocentesis. Although a high proportion of pregnant Japanese women agreed with the introduction of NIPT into Japanese obstetrical care, there was insufficient knowledge regarding the test. It is necessary for women undergoing NIPT to be provided sufficient information and psychological support.
キーワード amniocentesis Down syndrome fetal chromosome diagnosis non-invasive prenatal testing psychological support
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2015-06
巻 69巻
号 3号
出版者 Okayama University Medical School
開始ページ 155
終了ページ 163
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26101191
Web of Science KeyUT 000356903000004
JaLCDOI 10.18926/AMO/53521
フルテキストURL 69_3_145.pdf
著者 Ishii, Hiroko| Kamikawa, Shigeshi| Hirohata, Satoshi| Mizutani, Akifumi| Abe, Koji| Seno, Masaharu| Oohashi, Toshitaka| Ninomiya, Yoshifumi|
抄録 Eosinophil cationic protein (ECP) is well known as a cationic protein contained in the basic granules of activated eosinophils. Recent studies have reported that ECP exhibits novel activities on various types of cells, including rat neonatal cardiomyocytes. Here we evaluated the effects of ECP on rat cardiac myoblast H9c2 cells. Our results showed that ECP enhanced the survival of the cells, in part by promoting the ERK and Akt/GSK-3β signaling pathways. ECP attenuated the cytotoxic effects of H2O2 on H9c2 cells as well as the production of reactive oxygen species, the number of apoptotic cells and caspase 3/7 activity in the cells. In conclusion, ECP activated the ERK and Akt/GSK-3β pathways, resulting in anti-oxidative effects on H9c2 cells that attenuated apoptosis.
キーワード ECP reactive oxygen species Akt ERK
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2015-06
巻 69巻
号 3号
出版者 Okayama University Medical School
開始ページ 145
終了ページ 153
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26101190
Web of Science KeyUT 000356903000003
JaLCDOI 10.18926/AMO/53520
フルテキストURL 69_3_137.pdf
著者 Seki, Hiroyuki| Ikeda, Fusao| Nanba, Shintaro| Moritou, Yuki| Takeuchi, Yasuto| Yasunaka, Tetsuya| Onishi, Hideki| Miyake, Yasuhiro| Takaki, Akinobu| Nouso, Kazuhiro| Iwasaki, Yoshiaki| Nakamura, Minoru| Yamamoto, Kazuhide|
抄録 A predictive marker of the rapid progression to hepatic failure is desired for patients with asymptomatic primary biliary cirrhosis (aPBC). We performed a systematic cohort analysis of 101 patients diagnosed as having aPBC and the rapid progression to liver failure in some, by focusing on cholestasis. Cholestasis was assessed by aberrant keratin7 (K-7) expressions in the patientsʼ hepatocytes. Intralobular expressions of K-7 were found in 9 of the 101 patients. The grades of K-7 expression were significantly associated with the levels of alanine aminotransferase, alkaline phosphatase, and total bilirubin at the time of diagnosis, but not with bile duct loss or cholestasis. Stepwise logistic regression analysis revealed that high grades of K-7 expression correlated positively with high levels of total bilirubin. During the follow-up period, 8 patients developed jaundice, and the mean period until the development of jaundice was 5.2 years. The proportional hazards models for the risk of developing jaundice identified a high grade of aberrant K-7 expression in hepatocytes as the only significant risk factor. Aberrant K-7 expression in hepatocytes can be used as an additional marker to predict rapid progression to liver failure in patients with aPBC at the time of diagnosis.
キーワード primary biliary cirrhosis keratin 7 hepatic failure
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2015-06
巻 69巻
号 3号
出版者 Okayama University Medical School
開始ページ 137
終了ページ 144
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26101189
Web of Science KeyUT 000356903000002
JaLCDOI 10.18926/AMO/53519
フルテキストURL 69_3_129.pdf
著者 Akagi, Satoshi| Nakamura, Kazufumi| Matsubara, Hiromi| Ogawa, Aiko| Sarashina, Toshihiro| Ejiri, Kentaro| Ito, Hiroshi|
抄録 Pulmonary arterial hypertension (PAH) is characterized by elevation of pulmonary artery pressure caused by pulmonary vasoconstriction and vascular remodeling, which leads to right heart failure and death. Epoprostenol (prostaglandin I2) has a potent short-acting vasodilator property, and intravenous continuous epoprostenol is therefore used for treatment of PAH. Here we review evidence for the usefulness of intravenous continuous epoprostenol therapy in patients with PAH. Epoprostenol therapy is effective in idiopathic PAH patients and in patients with PAH associated with connective tissue disease, portal hypertension or congenital heart diseases, but it is not effective in patients with pulmonary veno-occlusive disease or pulmonary capillary hemangiomatosis. High-dose epoprostenol therapy markedly improved hemodynamics in some patients with PAH, possibly due to reverse remodeling of pulmonary arteries. This therapy has several side effects and complications such as headache, hypotension and catheter-related infections. Intravenous continuous epoprostenol is an effective treatment, but there are still some problems to be resolved.
キーワード pulmonary arterial hypertension epoprostenol high-dose complications side effects
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2015-06
巻 69巻
号 3号
出版者 Okayama University Medical School
開始ページ 129
終了ページ 136
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 26101188
Web of Science KeyUT 000356903000001
著者 座間味 義人| 高取 真吾| 合田 光寛| 小山 敏広| 岩谷 有希子| Jin, Xin| Takada-Doi, Shima| 川﨑 博己|
発行日 2008-11-01
出版物タイトル Biological & Pharmaceutical Bulletin
巻 31巻
号 11号
資料タイプ 学術雑誌論文
著者 座間味 義人| 高取 真吾| 小山 敏広| 合田 光寛| 岩谷 有希子| 土井 志真| 川﨑 博己|
発行日 2007-12-01
出版物タイトル 藥學雜誌
巻 127巻
号 12号
資料タイプ 学術雑誌論文
著者 座間味 義人| 高取 真吾| 岩谷 有希子| 山脇 康佑| 宮下 智子| 藪前 奈々| 高山 房子| 見尾 光庸| 川﨑 博己|
発行日 2008-03-01
出版物タイトル 藥學雜誌
巻 128巻
号 3号
資料タイプ 学術雑誌論文