検索結果 355 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Osinde, Cyprian| Sakamoto, Wataru| Kajiya-Kanegae, Hiromi| Sobhy, Islam S.| Tugume, Arthur K.| Nsubuga, Anthony M.| Galis, Ivan| |
| キーワード | Quantitative trait locus (QTL) stem borer herbivory BTx623 and NOG recombinant inbred lines (RILs) sorghum |
| 発行日 | 2023-12-31 |
| 出版物タイトル | Journal Of Plant Interactions |
| 巻 | 18巻 |
| 号 | 1号 |
| 出版者 | Taylor & Francis Ltd |
| 開始ページ | 2153182 |
| ISSN | 1742-9145 |
| NCID | AA11980303 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 The Author(s). |
| 論文のバージョン | publisher |
| DOI | 10.1080/17429145.2022.2153182 |
| Web of Science KeyUT | 000905581600001 |
| 関連URL | isVersionOf https://doi.org/10.1080/17429145.2022.2153182 |
| タイトル（別表記） | The beginning date of wet rice cultivation at the of Okayama University site: Tree ring oxygen isotope dating and radiocarbon 14 age of weirs from the mid-I stage of the Yayoi period |
|---|---|
| JaLCDOI | 10.18926/64199 |
| フルテキストURL | jdc_002_018.pdf |
| 著者 | 藤尾 慎一郎| 坂本 稔| 佐野 雅規| |
| 抄録 | This article clarifies the date when paddy field rice cultivation began at the archaeological site located within the Okayama University campus. The analysis used tree ring oxygen isotope dating and radiocarbon dating. When the oxygen isotope ratios of wood used in paddy weirs detected in the 23rd excavation season were examined, peaks could be seen in two places: in the 10th century BC and the 6th century BC. Since the weir was accompanied by mid-I stage Yayoi pottery, which was dated to the 6th century BC using radiocarbon dating, tree ring dating determined that the weir was made from wood cut down soon after 540 BC. Therefore, it was reaffirmed that one of the points of the mid-I stage can be dated to the middle of the 6th century BC. Next is the age of the early-I stage, when paddy field rice cultivation began on the Okayama Plain. In the Tsuruba area of the Nishikawazu archaeological site in Shimane Prefecture, where paddy field rice cultivation is thought to have begun at the same time as on the Okayama Plain, tree ring oxygen isotope dating of wood accompanied by early-I stage pottery has been reported. The date of 649 BC date means that one of the earliest stages of the early-I period dates to the middle of the 7th century BC. Therefore, we reaffirmed the view that paddy rice cultivation in the Chugoku region, such as Okayama and Shimane, began in the 7th century BC. It also became clear that the beginning of paddy field rice cultivation in the Chugoku region occurred at a time when the climate that had been the base of cold in the 10th century BC gradually warmed and the relatively humid climate began to turn to arid. |
| キーワード | 土器付着炭化物：carbides adhering to pottery 酸素同位体比年輪年代法：tree ring oxygen isotope dating 炭素14年代法：radiocarbon dating 岡山大学構内遺跡：the Okayama University site 弥生前期：the early Yayoi period 水田稲作：wet rice cultivation 堰：weirs |
| Amo Type | 研究ノート (Research note) |
| 出版物タイトル | 文明動態学 |
| 発行日 | 2023-03-25 |
| 巻 | 2巻 |
| 出版者 | 岡山大学文明動態学研究所 |
| 開始ページ | 18 |
| 終了ページ | 31 |
| ISSN | 2436-8326 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 日本語 |
| 著作権者 | © 2023 by RIDC |
| 論文のバージョン | publisher |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Daimon, Masahiro| Katsumura, Takafumi| Sakamoto, Hirotaka| Ansai, Satoshi| Takeuchi, Hideaki| |
| 発行日 | 2022-11-16 |
| 出版物タイトル | Scientific Reports |
| 巻 | 12巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 19665 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2022 |
| 論文のバージョン | publisher |
| PubMed ID | 36385126 |
| DOI | 10.1038/s41598-022-23871-w |
| Web of Science KeyUT | 000884825100096 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-022-23871-w |
| フルテキストURL | fulltext20221117-1.pdf |
|---|---|
| 著者 | Katayama, Yukitoshi| Miura, Ayane| Sakamoto, Tatsuya| Takanami, Keiko| Sakamoto, Hirotaka| |
| キーワード | itchy eyes histamine gastrin-releasing peptide receptor footedness |
| 発行日 | 2022-10-19 |
| 出版物タイトル | Proceedings of the Royal Society B: Biological Sciences |
| 巻 | 289巻 |
| 号 | 1985号 |
| 出版者 | The Royal Society |
| 開始ページ | 20221126 |
| ISSN | 0962-8452 |
| NCID | AA00786976 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 The Author(s) |
| 論文のバージョン | author |
| PubMed ID | 36259204 |
| DOI | 10.1098/rspb.2022.1126 |
| Web of Science KeyUT | 000872392900003 |
| 関連URL | isVersionOf https://doi.org/10.1098/rspb.2022.1126 |
| JaLCDOI | 10.18926/AMO/64127 |
|---|---|
| フルテキストURL | 76_6_749.pdf |
| 著者 | Takami, Masanari| Yukawa, Yasutsugu| Noda, Yusuke| Yoshida, Munehito| Yamada, Hiroshi| |
| 抄録 | We provide the first report of successful salvage surgery for a post-C1 laminectomy symptomatic recurrence of a retro-odontoid pseudotumor (ROP) that caused myelopathy. The 72-year-old Japanese woman presented with an ROP causing symptomatic cervical myelopathy. With ultrasonography support, we performed the enucleation of the ROP via a transdural approach and fusion surgery for the recurrence of the mass. At the final observation 2-year post-surgery, MRI demonstrated the mass’s regression and spinal cord decompression, and the patient’s symptoms had improved. Our strategy is an effective option for a symptomatic recurrence of ROP. |
| キーワード | recurrent retro-odontoid pseudotumor salvage surgery transdural resection C1 laminectomy ultra-sonography |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 749 |
| 終了ページ | 754 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549779 |
| Web of Science KeyUT | 000905195100017 |
| JaLCDOI | 10.18926/AMO/64126 |
|---|---|
| フルテキストURL | 76_6_743.pdf |
| 著者 | Tanaka, Masato| Suthar, Hardik| Desai, Dhvanit| Yamauchi, Taro| Arataki, Shinya| Fujiwara, Yoshihiro| Uotani, Koji| Oda, Yoshiaki| Misawa, Haruo| |
| 抄録 | We describe a floating technique via a posterolateral approach with intraoperative O-arm navigation to facilitate decompression of the spinal cord in thoracic myelopathy due to severe ossification of the posterior longitudinal ligament (OPLL). A 62-year-old man with myelopathy due to thoracic OPLL had left-leg muscle weakness, urinary disturbance, and spastic gait. Bilateral leg pain and gait disturbance had persisted for 2 years. He was successfully treated by the posterolateral OPLL floating procedure and posterior pedicle fixation under O-arm navigation. At a 2-year follow-up, manual muscle testing results and sensory function of the left leg had recovered fully. His cervical Japanese Orthopedic Association score had improved from 5/12 to 11/12. The novel intraoperative O-arm navigation-guided posterolateral floating procedure for thoracic OPLL is effective for achieving precise decompression and strong fixation with a posterior approach only and can provide an excellent result for severe thoracic OPLL without the risk of adverse events from intraoperative radiation. |
| キーワード | ossification of the posterior longitudinal ligament floating method navigation surgery C-arm free |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 743 |
| 終了ページ | 748 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549778 |
| Web of Science KeyUT | 000905195100016 |
| JaLCDOI | 10.18926/AMO/64122 |
|---|---|
| フルテキストURL | 76_6_715.pdf |
| 著者 | Mohammed Zahedul Islam Nizami| Gorduysus, Melahat| Shinoda-Ito, Yuki| Yamamoto, Tadashi| Nishina, Yuta| Takashiba, Shogo| Arias, Zulema| |
| 抄録 | The failure of endodontic treatment is directly associated with microbial infection in the root canal or periapical areas. An endodontic sealer that is both bactericidal and biocompatible is essential for the success of root canal treatments. This is one of the vital issues yet to be solved in clinical dental practice. This in vitro study assessed the effectiveness of graphene oxide (GO) composites GO-CaF2 and GO-Ag-CaF2 as endodontic sealer materials. Dentin slices were coated with either the GO-based composites or commonly used root canal sealers (non-eugenol zinc oxide sealer). The coated slices were treated in 0.9% NaCl, phosphate-buffered saline (PBS), and simulated body fluid (SBF) at 37˚C for 24 hours to compare their sealing effect on the dentin surface. In addition, the radiopacity of these composites was examined to assess whether they complied with the requirements of a sealer for good radiographic visualization. Scanning electron microscopy showed the significant sealing capability of the composites as coating materials. Radiographic images confirmed their radiopacity. Mineral deposition indicated their bioactivity, especially of GO-Ag-CaF2, and thus it is potential for regenerative application. They were both previously shown to be bactericidal to oral microbes and cytocompatible with host cells. With such a unique assemblage of critical properties, these GO-based composites show promise as endodontic sealers for protection against reinfection in root canal treatment and enhanced success in endodontic treatment overall. |
| キーワード | bioactive sealer graphene oxide mineral deposition antimicrobial activity radiopacity |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 715 |
| 終了ページ | 721 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549774 |
| Web of Science KeyUT | 000905195100012 |
| JaLCDOI | 10.18926/AMO/64120 |
|---|---|
| フルテキストURL | 76_6_695.pdf |
| 著者 | Onishi, Hideki| Nouso, Kazuhiro| Takaki, Akinobu| Oyama, Atsushi| Adachi, Takuya| Wada, Nozomu| Takeuchi, Yasuto| Shiraha, Hidenori| Okada, Hiroyuki| |
| 抄録 | This study sought to identify factors that are predictive of a therapeutic response to hepatic arterial infusion chemotherapy (HAIC) by focusing on the number of prior transcatheter arterial chemoembolization (TACE) sessions. To determine the parameters predicting a good response to HAIC, we retrospectively analyzed 170 patients with hepatocellular carcinoma (HCC) who received HAIC regimens comprising low-dose cisplatin combined with 5-fluorouracil (LFP) or cisplatin (CDDP) for the first time. In both the LFP and CDDP regimens, the response rates were significantly lower in patients with three or more prior TACE sessions than in those with two or fewer prior TACE sessions (LFP 57% versus 28%; p=0.01, CDDP 27% versus 6%; p=0.01). Multivariable logistic regression analysis revealed that the number of prior TACE sessions (≥ 3) was significantly associated with non-responder status (odds ratio 4.17, 95% Confidence Interval (CI) 1.76-9.86) in addition to the HAIC regimen. Multivariable analysis using the Cox proportional hazards model revealed that a larger number of prior TACE sessions (≥ 3) was a significant risk factor for survival (hazard ratio 1.60, 95% CI 1.12-2.29) in addition to Child-Pugh class, serum alpha-fetoprotein concentration, and maximum diameter of HCC. HCC patients who receive fewer prior TACE sessions (≤ 2) were found to be better responders to HAIC. |
| キーワード | hepatic arterial infusion chemotherapy hepatocellular carcinoma refractory transcatheter arterial chemoembolization |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 695 |
| 終了ページ | 703 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549772 |
| Web of Science KeyUT | 000905195100010 |
| JaLCDOI | 10.18926/AMO/64118 |
|---|---|
| フルテキストURL | 76_6_679.pdf |
| 著者 | Asagi, Akinori| Sakaguchi, Chihiro| Nadano, Seijin| Nishina, Tomohiro| Hamamoto, Yasushi| Kataoka, Masaaki| Yamashita, Natsumi| Tanimizu, Masahito| Hyodo, Ichinosuke| |
| 抄録 | Chemotherapy is insufficient to treat macroscopic vascular invasion (MVI) of hepatocellular carcinoma (HCC). We retrospectively investigated the treatment outcomes of patients who underwent three-dimensional conformal radiotherapy (3D-CRT) for HCC MVI and analyzed prognostic factors by multivariate analysis using a Cox proportional hazard model. Sixty-five patients were studied. MVI sites were the portal vein (n=48 patients), portal and hepatic veins (n=8), and hepatic vein (n=9). The median irradiation dose was 50 Gy. The median survival time (MST) was 7.5 months. Performance status 2 or 3, modified albumin-bilirubin grade 2b or 3, and massive/diffuse type were poor prognostic factors. Nineteen patients (29%) with a treatment effect of 3 or 4 (≥ 50% of tumor necrosis or regression) at the irradiation sites according to the Response Evaluation Criteria in Cancer of the Liver showed longer survival than those with an effect of 1 or 2 (MST 18.7 vs. 5.9 months, p<0.001). No treatment-related death occurred. The hepatic function reserve was preserved in more than 70% of patients. 3D-CRT controlled HCC MVI safely and was suggested to be a good treatment option. |
| キーワード | hepatocellular carcinoma macroscopic vascular invasion portal vein tumor thrombosis hepatic vein tumor thrombosis three-dimensional conformal radiotherapy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 679 |
| 終了ページ | 688 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549770 |
| Web of Science KeyUT | 000905195100008 |
| フルテキストURL | K0006684_abstract_review.pdf K0006684_fulltext.pdf K0006684_summary.pdf |
|---|---|
| 著者 | 橋本 望| |
| 発行日 | 2022-09-22 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第6684号 |
| 学位授与年月日 | 2022-09-22 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| 著作権者 | © 2022 Elsevier B.V. |
| JaLCDOI | 10.18926/AMO/64044 |
|---|---|
| フルテキストURL | 76_5_609.pdf |
| 著者 | Matsumoto, Ken| Fujishita, Keigo| Matsuda, Masayuki| Oka, Satoshi| Fujisawa, Yuka| Imai, Toshi| Machida, Takuya| |
| 抄録 | A 69-year-old Japanese man with acute leukemia received post-transplant cyclophosphamide-based haploidentical stem cell transplantation (PTCY-haplo-SCT) but was readmitted with dyspnea and ground-glass-opacities of the lungs. Bronchoscopy showed inflammatory changes with no signs of infection. He received steroids but required intubation as his condition deteriorated. In addition to antithymocyte globulin and cyclophosphamide, we administered ruxolitinib but failed to save him. Autopsy findings revealed fibrotic nonspecific interstitial pneumonia (NSIP) without evidence of organizing pneumonia or infection. Thus, we diagnosed idiopathic pneumonia syndrome (IPS). As far as our knowledge, this is the first case of IPS with NSIP histology after PTCY-haplo-SCT. |
| キーワード | idiopathic pneumonia syndrome ruxolitinib post-transplant cyclophosphamide-based haploidentical stem cell transplantation nonspecific interstitial pneumonia |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-10 |
| 巻 | 76巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 609 |
| 終了ページ | 615 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36352810 |
| Web of Science KeyUT | 000884907100016 |
| JaLCDOI | 10.18926/AMO/64040 |
|---|---|
| フルテキストURL | 76_5_585.pdf |
| 著者 | Choshi, Haruki| Watanabe, Mototsugu| Furukawa, Shinichi| Ujike, Hiroyuki| Kataoka, Kazuhiko| |
| 抄録 | Pulmonary metastatic resection is a standard therapy for renal cell carcinoma (RCC). Although patients with pulmonary metastases who do not undergo any treatment have poor prognoses, it has been reported that resection for pulmonary metastases yields good clinical outcomes. We investigated the prognoses of the 10 Japanese patients (eight males, two females) who underwent a surgical resection of pulmonary metastasectomy from RCC at our institution between April 1, 2012 and March 31, 2020 and analyzed the prognostic factors. We determined the prognoses and calculated the 5-year overall survival (OS) and disease-free survival (DFS) rates. To identify prognostic factors, we compared the median DFS duration for each factor. Elderly patients (median age, 75.5 years) were more predominant compared to previous studies, and all 10 patients underwent a complete resection. The 5-year DFS rate was 30.5% (95%CI: 0.045-0.63) and the 5-year OS rate was 80% (95%CI: 0.20-0.97). The following factors were associated with better prognosis: female, disease-free interval≥36 months, and metastases size<12 mm. These results indicate that complete resection for pulmonary metastases from RCC resulted in good clinical outcomes, particularly for patients with better prognostic factors. |
| キーワード | renal cell carcinoma pulmonary metastasis complete resection |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-10 |
| 巻 | 76巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 585 |
| 終了ページ | 591 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36352806 |
| Web of Science KeyUT | 000884907100012 |
| JaLCDOI | 10.18926/AMO/64031 |
|---|---|
| フルテキストURL | 76_5_511.pdf |
| 著者 | Tomita, Hayato| Kuramochi, Kenji| Fujikawa, Atsuko| Ikeda, Hirotaka| Komita, Midori| Kurihara, Yoshiko| Kobayashi, Yasuyuki| Mimura, Hidefumi| |
| 抄録 | Iterative reconstruction (IR) improves image quality compared with filtered back projection (FBP). This study investigated the usefulness of model-based IR (forward-projected model-based iterative reconstruction solution [FIRST]) in comparison with FBP and hybrid IR (adaptive iterative dose reduction three-dimensional processing [AIDR 3D]) in low-dose paranasal CT. Twenty-four patients with paranasal sinusitis who underwent standard-dose CT (120 kV) and low-dose CT (100 kV) scanning before and after medical treatment were enrolled. Standard-dose CT scans were reconstructed with FBP (FBP120), and low-dose CT scans with FBP (FBP100), AIDR 3D, and FIRST. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in three anatomical structures and effective doses were compared using Mann–Whitney U test. Two radiologists independently evaluated the visibility of 16 anatomical structures, overall image quality, and artifacts. Effective doses in lowdose CT were significantly reduced compared with those in standard-dose CT (0.24 vs 0.43 mSv, p<0.001). FIRST achieved significantly higher SNR (p<0.01, respectively) and CNR (p<0.001, respectively) of evaluated structures and significant improvement in overall image quality (p<0.001), artifacts (p<0.001), and visibility related to muscles (p<0.05) compared to FBP120, FBP100, and AIDR 3D. FIRST allowed radiation-dose reduction, while maintaining objective and subjective image quality in low-dose paranasal CT. |
| キーワード | paranasal sinuses iterative reconstruction dose reduction low dose |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-10 |
| 巻 | 76巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 511 |
| 終了ページ | 517 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36352797 |
| Web of Science KeyUT | 000884907100003 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kashimoto, Rena| Furukawa, Saya| Yamamoto, Sakiya| Kamei, Yasuhiro| Sakamoto, Joe| Nonaka, Shigenori| Watanabe, Tomonobu M.| Sakamoto, Tatsuya| Sakamoto, Hirotaka| Satoh, Akira| |
| 発行日 | 2022-07-15 |
| 出版物タイトル | iScience |
| 巻 | 25巻 |
| 号 | 7号 |
| 出版者 | CELL PRESS |
| 開始ページ | 104524 |
| ISSN | 2589-0042 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 35754731 |
| DOI | 10.1016/j.isci.2022.104524 |
| Web of Science KeyUT | 000828186100005 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.isci.2022.104524 |
| JaLCDOI | 10.18926/AMO/63720 |
|---|---|
| フルテキストURL | 76_3_265.pdf |
| 著者 | Kosaki, Yoshinori| Naito, Hiromichi| Iida, Atsuyoshi| Ihoriya, Hiromi| Nojima, Tsuyoshi| Yamada, Taihei| Yamamoto, Hirotsugu| Nakamura, Shunsuke| Mandai, Yasuhiro| Nakao, Atsunori| |
| 抄録 | Basic life support (BLS) courses for laypersons, including cardiopulmonary resuscitation (CPR) training, is known to improve outcomes of out-of-hospital cardiac events. We asked medical students to provide BLS training for laypersons as a part of their emergency medicine education and evaluated the effects of training on the BLS skills of laypersons. We also used a questionnaire to determine whether the medical students who provided the BLS training were themselves more confident and motivated to perform BLS compared to students who did not provide BLS training. The proportions of laypersons who reported confidence in checking for a response, performing chest compressions, and automated external defibrillator (AED) use were significantly increased after the BLS training. The proportions of medical students who reported increased confidence/motivation in terms of understanding BLS, checking for a response, chest compression, use of AED, and willingness to perform BLS were significantly greater among medical students who provided BLS instructions compared to those who did not. BLS instruction by medical students was associated with an improvement in laypersons’ CPR accuracy and confidence in responding to cardiac arrest. The results indicate that medical students could gain understanding, confidence, and motivation in regard to their BLS skills by teaching BLS to laypersons. |
| キーワード | BLS medical education emergency medicine resuscitation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 265 |
| 終了ページ | 271 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790356 |
| Web of Science KeyUT | 000823568300005 |
| JaLCDOI | 10.18926/AMO/63719 |
|---|---|
| フルテキストURL | 76_3_255.pdf |
| 著者 | Nakatsuka, Kosuke| Matsuoka, Yoshikazu| Kurita, Masako| Wang, Ruilin| Tsuboi, Chika| Sue, Nobutaka| Kaku, Ryuji| Morimatsu, Hiroshi| |
| 抄録 | Mirror image pain (MIP) is a type of extraterritorial pain that results in contralateral pain or allodynia. Glutamate transporter-1 (GLT-1) is expressed in astrocytes and plays a role in maintaining low glutamate levels in the synaptic cleft. Previous studies have shown that GLT-1 dysfunction induces neuropathic pain. Our previous study revealed bilateral GLT-1 downregulation in the spinal cord of a spared nerve injury (SNI) rat. We hypothesized that spinal GLT-1 is involved in the mechanism of MIP. We also previously demonstrated noradrenergic GLT-1 regulation. Therefore, this study aimed to investigate the effect of an α1 adrenergic antagonist on the development of MIP. Rats were subjected to SNI. Changes in pain behavior and GLT-1 protein levels in the SNI rat spinal cords were then examined by intrathecal administration of the α1 adrenergic antagonist phentolamine, followed by von Frey test and western blotting. SNI resulted in the development of MIP and bilateral downregulation of GLT-1 protein in the rat spinal cord. Intrathecal phentolamine increased contralateral GLT-1 protein levels and partially ameliorated the 50% paw withdrawal threshold in the contralateral hind paw. Spinal GLT-1 upregulation by intrathecal phentolamine ameliorates MIP. GLT-1 plays a role in the development of MIPs. |
| キーワード | alpha adrenergic receptor glutamate transporter-1 mirror image pain neuropathic pain spared nerve injury |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 255 |
| 終了ページ | 263 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790355 |
| Web of Science KeyUT | 000823568300004 |
| JaLCDOI | 10.18926/AMO/63718 |
|---|---|
| フルテキストURL | 76_3_247.pdf |
| 著者 | Yoshida, Shohei| Fujii, Nobuharu| Kamoi, Chihiro| Kitamura, Wataru| Fujiwara, Hideaki| Asada, Noboru| Nishimori, Hisakazu| Fujii, Keiko| Matsuoka, Ken-ichi| Maeda, Yoshinobu| |
| 抄録 | Vaccine-preventable disease (VPD) infections are more severe in immunocompromised hosts. Vaccination against measles, mumps, rubella, and varicella zoster (VZV) (MMRV) is therefore recommended for hematopoietic stem cell transplantation (HCT) recipients. However, studies on adult HCT recipients with VPD infections are limited. At our institution, we have systematically conducted serological MMRV tests as a part of check-up examinations during long-term follow-up (LTFU) after HCT since 2015. This retrospective study aimed to evaluate changes in the serostatus between before and 2 years after allogeneic HCT. Among 161 patients, the pre-transplant seropositivity was 82.7% for measles, 86.8% for mumps, 84.2% for rubella, and 94.3% for VZV. Among 56 patients who underwent LTFU including serological MMRV tests at 2 years after HCT, the percentages maintaining seroprotective antibody levels for measles, mumps, rubella and VZV were 71.5% (40/56), 51.8% (29/56), 48.2% (27/56), and 60.7% (34/56), respectively. Vaccination was recommended for 22 patients, and 12 were vaccinated. Among the 12 vaccinated patients, rates of seroconversion were examined in 2-6 patients for each of the four viruses. They were 100% (3/3) for measles, 33.3% (1/3) for mumps, 50% (3/6) for rubella, and 0% (0/2) for VZV. Further studies are warranted to clarify the effect of vaccination in adult HCT recipients. |
| キーワード | vaccine-preventable disease vaccination allogeneic hematopoietic stem cell transplantation adult |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 247 |
| 終了ページ | 253 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790354 |
| Web of Science KeyUT | 000823568300003 |
| フルテキストURL | K0006530_abstract_review.pdf K0006530_fulltext.pdf K0006530_summary.pdf |
|---|---|
| 著者 | 久保 光太郎| |
| 発行日 | 2022-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第6530号 |
| 学位授与年月日 | 2022-03-25 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| 著作権者 | © 2021 Japan Society of Obstetrics and Gynecology. |
| フルテキストURL | fulltext20220602-3.pdf Supplementary_Data20220602-3.pdf Figure1.tiff Figure2.tiff Figure3.tiff Figure4.tiff Figure5.tiff Figure6.tiff Figure7.tiff Figure8.tiff |
|---|---|
| 著者 | Wahinya, Fiona Wacera| Yamazaki, Kiyoshi| Jing, Zihuan| Takami, Tsuneaki| Kamiya, Takehiro| Kajiya-Kanegae, Hiromi| Takanashi, Hideki| Iwata, Hiroyoshi| Tsutsumi, Nobuhiro| Fujiwara, Toru| Sakamoto, Wataru| |
| 備考 | This is a pre-copyedited, author-produced version of an article accepted for publication in [Plant and Cell Physiology] following peer review. The version of record [Fiona Wacera Wahinya, Kiyoshi Yamazaki, Zihuan Jing, Tsuneaki Takami, Takehiro Kamiya, Hiromi Kajiya-Kanegae, Hideki Takanashi, Hiroyoshi Iwata, Nobuhiro Tsutsumi, Toru Fujiwara, Wataru Sakamoto, Sorghum Ionomics Reveals the Functional SbHMA3a Allele that Limits Excess Cadmium Accumulation in Grains, Plant and Cell Physiology, Volume 63, Issue 5, May 2022, Pages 713–728, https://doi.org/10.1093/pcp/pcac035] is available online at: https://doi.org/10.1093/pcp/pcac035| |
| 発行日 | 2022-3-21 |
| 出版物タイトル | Plant and Cell Physiology |
| 巻 | 63巻 |
| 号 | 5号 |
| 出版者 | Oxford University Press (OUP) |
| 開始ページ | 713 |
| 終了ページ | 728 |
| ISSN | 0032-0781 |
| NCID | AA0077511X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2022. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. |
| 論文のバージョン | author |
| PubMed ID | 35312772 |
| DOI | 10.1093/pcp/pcac035 |
| Web of Science KeyUT | 000797640800001 |
| 関連URL | isVersionOf https://doi.org/10.1093/pcp/pcac035 |
| フルテキストURL | fulltext20220525-1.pdf |
|---|---|
| 著者 | Kobayashi, Aoshi| Hamada, Mayuko| Yoshida, Masa-aki| Kobayashi, Yasuhisa| Tsutsui, Naoaki| Sekiguchi, Toshio| Matsukawa, Yuta| Maejima, Sho| Gingell, Joseph J.| Sekiguchi, Shoko| Hamamoto, Ayumu| Hay, Debbie L.| Morris, John F.| Sakamoto, Tatsuya| Sakamoto, Hirotaka| |
| 発行日 | 2022-3-4 |
| 出版物タイトル | Science Advances |
| 巻 | 8巻 |
| 号 | 9号 |
| 出版者 | American Association for the Advancement of Science (AAAS) |
| 開始ページ | eabk0331 |
| ISSN | 2375-2548 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | Copyright © 2022 The Authors, some rights reserved |
| 論文のバージョン | publisher |
| PubMed ID | 35245108 |
| DOI | 10.1126/sciadv.abk0331 |
| Web of Science KeyUT | 000790020300008 |
| 関連URL | isVersionOf https://doi.org/10.1126/sciadv.abk0331 |