検索結果 - 岡山大学学術成果リポジトリ

“Active Guide” Brochure Reduces Sedentary Behavior of Elderly People: A Randomized Controlled Trial

JaLCDOI	10.18926/AMO/57373
フルテキストURL	73_5_427.pdf
著者	Owari, Yutaka\| Suzuki, Hiromi\| Miyatake, Nobuyuki\|
抄録	The aim of this study was to examine in a randomized controlled trial how much the sedentary behavior (sitting time) of community-dwelling elderly Japanese subjects decreased as a result of using the “Active Guide” brochure published by the Ministry of Health, Labour and Welfare (2013) and additional documents related to the benefits of reducing sedentary behavior. A total of 86 elderly people who participated in health-club activities for one year were randomly allocated to two groups. Subjects in the intervention group received explanations of the importance of physical activity using the “Active Guide” brochure (n=42) and additional documents, while subjects in the control group did not (n=44). Physical activity was measured using a triaxial accelerometer for two weeks at baseline and again after one year. After one year of intervention, the difference in the sedentary behavior rate from baseline was −2.2% for the intervention group (n=40) and +2.5% for controls (n=40) (Welch’s t-test, p=0.007). Use of the “Active Guide” brochure and additional documents may reduce the sedentary behavior of community dwelling elderly people in Japan.
キーワード	Active Guide sedentary behavior elderly people randomized controlled trial health promotion
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-10
巻	73巻
号	5号
出版者	Okayama University Medical School
開始ページ	427
終了ページ	432
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31649369
Web of Science KeyUT	000491886600008

Relationship between Sedentary Behavior and All-cause Mortality in Japanese Chronic Hemodialysis Patients: A Prospective Cohort Study

JaLCDOI	10.18926/AMO/57372
フルテキストURL	73_5_419.pdf
著者	Hishii, Shuhei\| Miyatake, Nobuyuki\| Nishi, Hiroyuki\| Katayama, Akihiko\| Ujike, Kazuhiro\| Koumoto, Kiichi\| Suzuki, Hiromi\| Hashimoto, Hiroo\|
抄録	We investigated the relationship between sedentary behavior and all-cause mortality in patients undergoing hemodialysis. A total of 71 patients (39 men, 32 women, aged 72.1±11.7 years) were enrolled in this longitudinal study. Their sedentary behavior was measured using a tri-accelerometer that provides relative values per daily wearing time. We classified the sedentary behavior time into 2 groups (under the median: short-sedentary behavior (SB) group; over the median: long-SB group) and compared the groups’ clinical parameters. We compared the groups’ survival rates by using Kaplan-Meier curves and the log-rank test, and we performed multivariate analyses by a Cox-proportional hazard model to evaluate the relationship between the sedentary behavior and the survival rate. Twenty patients (28.2%) died during the observation period. The survival rate of the short-SB group was significantly higher than that of the long-SB group. Sedentary behavior was thus an important factor for all-cause mortality even after adjusting for confounding factors by a Cox-proportional hazard model. Sedentary behavior is closely linked to all-cause mortality, especially total days and non-hemodialysis days, and reducing sedentary behavior may be beneficial to reduce the all-cause mortality of patients on chronic hemodialysis.
キーワード	sedentary behavior hemodialysis mortality physical activity
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-10
巻	73巻
号	5号
出版者	Okayama University Medical School
開始ページ	419
終了ページ	425
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31649368
Web of Science KeyUT	000491886600007

Feasibility of Laparoscopic Radical Cystectomy in Elderly Patients: A Comparative Analysis of Clinical Outcomes in a Single Institution

JaLCDOI	10.18926/AMO/57371
フルテキストURL	73_5_413.pdf
著者	Yanagihara, Yutaka\| Nishida, Keigo\| Watanabe, Ryuta\| Koyama, Kanae\| Sawada, Yuichiro\| Noda, Terutaka\| Asai, Seiji \| Fukumoto, Tetsuya\| Miura, Noriyoshi\| Miyauchi, Yuki\| Kikugawa, Tadahiko\| Saika, Takashi\|
抄録	Laparoscopic radical cystectomy (LRC) is a standard surgical treatment for muscle-invasive bladder cancer and high-risk non-muscle-invasive bladder cancer. LRC is a less invasive modality than conventional open surgery. Therefore, even elderly patients with invasive bladder cancer may be candidates for LRC. In this study, a comparative analysis of perioperative/oncological outcomes between elderly patients and younger patients who underwent LRC was performed to assess the feasibility of LRC in elderly patients. Sixty-eight consecutive patients who underwent LRC between October 2013 and March 2018 were enrolled and stratified into those younger than 75 years (n=37) and those ≥ 75 years old (n=31). The median follow-up period was 28.2 months. The preoperative and operative parameters and complications were similar in both groups. The 2-year overall survival (OS) was 64.4% in the younger vs. 76.4% in the elderly group (p=0.053), cancer-specific survival (CSS) was 79.3% vs. 81.7% (p=0.187), and recurrence-free survival (RFS) was 58.2% vs. 75.7% (p=0.174), respectively. No significant differences were observed in OS, CSS, or RFS between the groups. No significant differences were found between the groups with respect to peri-surgical/oncological outcomes. We conclude that LRC is feasible in elderly patients.
キーワード	bladder cancer laparoscopic surgery radical cystectomy elderly patient
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-10
巻	73巻
号	5号
出版者	Okayama University Medical School
開始ページ	417
終了ページ	418
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31649367
Web of Science KeyUT	000491886600006

Formation of Hot Ice Caused by Carbon Nanobrushes

フルテキストURL	J_ChemPhys_151_064702_p.pdf
著者	Yagasaki, Takuma\| Yamasaki, Masaru\| Matsumoto, Masakazu\| Tanaka, Hideki\|
備考	This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Takuma Yagasaki et. al. Formation of hot ice caused by carbon nanobrushes. The Journal of Chemical Physics 151(6), 064702 (2019)(citation of published article) and may be found at https://doi.org/10.1063/1.5111843.\|
発行日	2019-08-08
出版物タイトル	The Journal of Chemical Physics
巻	151巻
号	6号
出版者	American Institute of Physics
開始ページ	064702
ISSN	00219606
NCID	AA00694991
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	Copyright (2019) Author(s)
論文のバージョン	publisher
DOI	10.1063/1.5111843
関連URL	isVersionOf https://doi.org/10.1063/1.5111843

Behavioural effects of inhalation exposure to dizocilpine (MK-801) in mice

フルテキストURL	Biomed_Pharmacother_2019109038.pdf
著者	Ueno, Hiroshi\| Suemitsu, Shunsuke\| Murakami, Shinji\| Kitamura, Naoya\| Wani, Kenta\| Takahashi, Yu\| Matsumoto, Yosuke\| Okamoto, Motoi\| Ishihara, Takeshi\|
キーワード	Inhalation Dizocilpine MK-801 Mouse Drug Schizophrenia
発行日	2019-09-30
出版物タイトル	Biomedicine & Pharmacotherapy
巻	117巻
出版者	Elsevier
開始ページ	109038
ISSN	07533322
NCID	AA10506249
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 The Authors. Published by Elsevier Masson SAS.
論文のバージョン	publisher
PubMed ID	31177060
DOI	10.1016/j.biopha.2019.109038
Web of Science KeyUT	000477804500018
関連URL	isVersionOf https://doi.org/10.1016/j.biopha.2019.109038

Two novel fungal negative-strand RNA viruses related to mymonaviruses and phenuiviruses in the shiitake mushroom (Lentinula edodes)

フルテキストURL	Virology_533_125.pdf
著者	Lin, Yu-Hsin\| Fujita, Miki\| Chiba, Sotaro\| Hyodo, Kiwamu\| Andika, Ida Bagus\| Suzuki, Nobuhiro\| Kondo, Hideki\|
キーワード	Ambisense Bipartite genome Endogenous virus element Evolution High-throughput sequencing Lentinula edodes Mymonaviridae Negative-strand RNA virus Phenuiviridae Shitake mushroom
備考	This fulltext will be available in May 2020\|
発行日	2019-07-31
出版物タイトル	Virology
巻	533巻
出版者	Academic Press
開始ページ	125
終了ページ	136
ISSN	00426822
NCID	AA00884454
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	31153047
DOI	10.1016/j.virol.2019.05.008
Web of Science KeyUT	000474941300015
関連URL	isVersionOf https://doi.org/10.1016/j.virol.2019.05.008

A proposed simple screening method to determine relative contributions of CYP3A4 and CYP3A5 to drug metabolism in vitro

フルテキストURL	PMU8_41.pdf Fig.pdf Suppl.pdf
著者	Matsumoto, Jun\| Nakamura, Hiroyoshi\| San, Su Nwe\| Sato, Hikari\| Takezawa, Manami\| Kishi, Ryuto\| Kito, Yutaro\| Sugano, Junko\| Izuki, Mai\| Yanagisawa, Nao\| Ikeda, Naoki\| Saito, Yusuke\| Kato, Yoshinori\| Yamada, Harumi\| Fujiyoshi, Masachika\| Ariyoshi, Noritaka\|
キーワード	CYP3A CYP3A5*3 allele P450 Glo Assay system Pharmacokinetics Pharmacogenetics
発行日	2019-07-31
出版物タイトル	Personalized Medicine Universe
巻	8巻
出版者	Elsevier B.V.
開始ページ	41
終了ページ	44
ISSN	21867070
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
DOI	10.1016/j.pmu.2019.04.001
関連URL	isVersionOf https://doi.org/10.1016/j.pmu.2019.04.001

Efficient and practical synthesis of N-acetyl enamides from ketoximes by unique iron catalytic system

フルテキストURL	TL60_24_1562.pdf
著者	Kunishige, Takahiro\| Sawada, Daisuke\|
キーワード	Ketoxime Enamide synthesis Iron catalyst One-electron reduction
備考	This fulltext will be available in May 2021\|
発行日	2019-06-13
出版物タイトル	Tetrahedron Letters
巻	60巻
号	24号
出版者	PERGAMON-ELSEVIER SCIENCE
開始ページ	1562
終了ページ	1565
ISSN	00404039
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
DOI	10.1016/j.tetlet.2019.05.006
Web of Science KeyUT	000495464900002
関連URL	isVersionOf https://doi.org/10.1016/j.tetlet.2019.05.006

Induction of Expandable Tissue-Specific Progenitor Cells from Human Pancreatic Tissue through Transient Expression of Defined Factors

フルテキストURL	fulltext.pdf
著者	Noguchi, Hirofumi\| Miyagi-Shiohira, Chika\| Nakashima, Yoshiki\| Kinjo, Takao\| Kobayashi, Naoya\| Saitoh, Issei\| Watanabe, Masami\| Shapiro, A. M. James\| Kin, Tatsuya\|
キーワード	induced tissue-specific progenitor cells iTP induced tissue-specific stem cells iTS induced pluripotent stem cells iPSCs reprogramming factors pancreas
発行日	2019-06-14
出版物タイトル	Molecular Therapy - Methods and Clinical Development
巻	13巻
出版者	Cell Press
開始ページ	243
終了ページ	252
ISSN	2329-0501
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 The Author(s).
論文のバージョン	publisher
PubMed ID	30828587
DOI	10.1016/j.omtm.2019.01.011
Web of Science KeyUT	000471284200022
関連URL	isVersionOf https://doi.org/10.1016/j.omtm.2019.01.011

Pullout repair using modified Mason-Allen suture induces better meniscal healing and superior clinical outcomes: A comparison between two surgical methods

フルテキストURL	Knee26_3_653.pdf tables.pdf Fig.pdf
著者	Furumatsu, Takayuki\| Okazaki, Yuki\| Kodama, Yuya\| Okazaki, Yoshiki\| Masuda, Shin\| Kamatsuki, Yusuke\| Takihira, Shota\| Hiranaka, Takaaki\| Yamawaki, Tadashi\| Ozaki, Toshifumi\|
キーワード	Clinical outcome Medial meniscus Meniscal healing Posterior root tear Transtibial pullout repair
発行日	2019-06-30
出版物タイトル	The Knee
巻	26巻
号	3号
出版者	Elsevier
開始ページ	653
終了ページ	659
ISSN	09680160
NCID	AA10996272
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 Elsevier B.V. All rights reserved.
論文のバージョン	author
PubMed ID	30902517
DOI	10.1016/j.knee.2019.02.007
Web of Science KeyUT	000474504500017
関連URL	isVersionOf https://doi.org/10.1016/j.knee.2019.02.007

Imaging an intrapulmonary solitary fibrous tumor with CT and F-18 FDG PET/CT

著者	Shinya, Takayoshi\| Masaoka, Yoshihisa\| Sando, Motohiro\| Tanabe, Shin\| Okamoto, Soichiro\| Ihara, Hiroki\| Tanaka, Takehiro\| Otani, Shinji\| Hiraki, Takao\| Kanazawa, Susumu\|
キーワード	Solitary fibrous tumor (SFT) Intrapulmonary Computed tomography (CT)
発行日	2019-06
出版物タイトル	Radiology Case Reports
巻	14巻
号	6号
出版者	Elsevier
開始ページ	755
終了ページ	758
ISSN	1930-0433
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 The Authors.
論文のバージョン	publisher
PubMed ID	30992735
DOI	10.1016/j.radcr.2019.03.023
関連URL	isVersionof https://doi.org/10.1016/j.radcr.2019.03.023

Combination of Diclofenac and Sublingual Nitrates Is Superior to Diclofenac Alone in Preventing Pancreatitis After Endoscopic Retrograde Cholangiopancreatography

フルテキストURL	Gastroenterology156_6_1753.pdf fig.pdf
著者	Tomoda, Takeshi\| Kato, Hironari\| Ueki, Toru\| Akimoto, Yutaka\| Hata, Hidenori\| Fujii, Masakuni\| Harada, Ryo\| Ogawa, Tsuneyoshi\| Wato, Masaki\| Takatani, Masahiro\| Matsubara, Minoru\| Kawai, Yoshinari\| Okada, Hiroyuki\|
キーワード	Drug Inflammation Pancreas Smooth-Muscle Relaxant
発行日	2019-05-31
出版物タイトル	Gastroenterology
巻	156巻
号	6号
出版者	W B SAUNDERS CO-ELSEVIER
開始ページ	1753
終了ページ	1760
ISSN	00165085
NCID	AA0065394X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	30772342
DOI	10.1053/j.gastro.2019.01.267
Web of Science KeyUT	10.1053/j.gastro.2019.01.267
関連URL	isVersionOf https://doi.org/10.1053/j.gastro.2019.01.267

Significance of IgG4-positive cells in severe eosinophilic chronic rhinosinusitis

フルテキストURL	fulltext.pdf
著者	Koyama, Takahisa\| Kariya, Shin\| Sato, Yasuharu\| Gion, Yuka\| Higaki, Takaya\| Haruna, Takenori\| Fujiwara, Tazuko\| Minoura, Akira\| Takao, Soshi\| Orita, Yorihisa\| Kanai, Kengo\| Taniguchi, Masami\| Nishizaki, Kazunori\| Okano, Mitsuhiro\|
キーワード	Chronic rhinosinusitis Eosinophils IgG4 Nasal polyps Severity
発行日	2019-04-30
出版物タイトル	Allergology International
巻	68巻
号	2号
出版者	Elsevier
開始ページ	216
終了ページ	224
ISSN	13238930
NCID	AA11091750
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 Japanese Society of Allergology. Production and hosting by Elsevier B.V.
論文のバージョン	publisher
PubMed ID	30316748
DOI	10.1016/j.alit.2018.09.002
Web of Science KeyUT	000462852200012
関連URL	isVersionOf https://doi.org/10.1016/j.alit.2018.09.002

Early childhood exposure to maternal smoking and Kawasaki Disease: A longitudinal survey in Japan

フルテキストURL	SciTotalEnviron_201811194.pdf
著者	Yorifuji, Takashi\| Tsukahara, Hirokazu\| Doi, Hiroyuki\|
キーワード	Early childhood exposure Epidemiology Mucocutaneous lymph node syndrome; Smoking
発行日	2019-03-10
出版物タイトル	Science of The Total Environment
巻	655巻
出版者	Elsevier
開始ページ	141
終了ページ	146
ISSN	00489697
NCID	AA00836666
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	30469059
DOI	10.1016/j.scitotenv.2018.11.194
Web of Science KeyUT	000455034600013
関連URL	isVersionOf https://doi.org/10.1016/j.scitotenv.2018.11.194

Transtibial pullout repair of medial meniscus posterior root tear restores physiological rotation of the tibia in the knee-flexed position

フルテキストURL	OTSR105_1_113.pdf Fig.pdf
著者	Okazaki, Yuki\| Furumatsu, Takayuki\| Kodama, Yuya\| Hino, Tomohito\| Kamatsuki, Yusuke\| Okazaki, Yoshiki\| Masuda, Shin\| Miyazawa, Shinichi\| Endo, Hirosuke\| Tetsunaga, Tomonori\| Yamada, Kazuki\| Ozaki, Toshifumi\|
キーワード	Magnetic resonance imaging Medial meniscus Posterior root tear Tibial rotation Transtibial pullout repair
発行日	2019-02-28
出版物タイトル	Orthopaedics & Traumatology: Surgery & Research
巻	105巻
号	1号
出版者	Elsevier
開始ページ	113
終了ページ	117
ISSN	18770568
資料タイプ	学術雑誌論文
言語	日本語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	30482466
DOI	10.1016/j.otsr.2018.10.005
Web of Science KeyUT	000456541300019
関連URL	isVersionOf https://doi.org/10.1016/j.otsr.2018.10.005

Injury patterns of medial meniscus posterior root tears

フルテキストURL	OTSR105_1_107.pdf Fig.pdf
著者	Furumatsu, Takayuki\| Okazaki, Yuki\| Okazaki, Yoshiki\| Hino, Tomohito\| Kamatsuki, Yusuke\| Masuda, Shin\| Miyazawa, Shinichi\| Nakata, Eiji\| Hasei, Joe\| Kunisada, Toshiyuki\| Ozaki, Toshifumi\|
キーワード	Descending knee motion Injury pattern Medial meniscus Posterior root tear Squatting
発行日	2019-02-28
出版物タイトル	Orthopaedics & Traumatology: Surgery & Research
巻	105巻
号	1号
出版者	Elsevier
開始ページ	107
終了ページ	111
ISSN	18770568
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	30442555
DOI	10.1016/j.otsr.2018.10.001
Web of Science KeyUT	000456541300018
関連URL	isVersionOf https://doi.org/10.1016/j.otsr.2018.10.001

Digital transfer of the subgingival contour and emergence profile of the provisional restoration to the final bone-anchored fixed restoration

フルテキストURL	JPR63_1_125.pdf Fig.pdf
著者	Kurosaki, Yoko\| Mino, Takuya\| Maekawa, Kenji\| Izumi, Koji\| Kuboki, Takuo\|
キーワード	Digital transfer Emergence profile Implant fixed restoration In silico analysis Subgingival contour
発行日	2019-01-31
出版物タイトル	Journal of Prosthodontic Research
巻	63巻
号	1号
開始ページ	125
終了ページ	129
ISSN	18831958
NCID	AA12395171
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	30455114
DOI	10.1016/j.jpor.2018.10.004
関連URL	isVersionOf https://doi.org/10.1016/j.jpor.2018.10.004

CACNA1A variants may modify the epileptic phenotype of Dravet syndrome

フルテキストURL	NeurobiolDis_50_209.pdf
著者	Ohmori, Iori\| Ouchida, Mamoru\| Kobayashi, Katsuhiro\| Jitsumori, Yoshimi\| Mori, Akiko\| Michiue, Hiroyuki\| Nishiki, Teiichi\| Ohtsuka, Yoko\| Matsui, Hideki\|
備考	CACNA1A variants contribute to severity of seizures in Dravet syndrome\|
発行日	2013-02
出版物タイトル	Neurobiology of disease
巻	50巻
出版者	Academic Press
開始ページ	209
終了ページ	217
ISSN	09699961
NCID	AA11645502
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	23103419
DOI	10.1016/j.nbd.2012.10.016
Web of Science KeyUT	000313758100023
関連URL	isVersionOf https://doi.org/10.1016/j.nbd.2012.10.016

A Patient with Type 3 Autoimmune Polyglandular Syndrome who Developed Systemic Lupus Erythematosus 8 years after the Diagnosis of Autoimmune Hepatitis

JaLCDOI	10.18926/AMO/56940
フルテキストURL	73_4_367.pdf
著者	Mifune-Morioka, Tomoyo\| A. Uchida, Haruhito\| Fukushima, Kazuhiko\| Watanabe, Mayu\| Ouchi, Chihiro\| Mise, Koki\| Kawakita, Chieko\| Kano, Yuzuki\| Onishi, Akifumi\| Toma, Kishio\| Eguchi, Jun\| Wada, Nozomu\| Ikeda, Fusao\| Sasaki, Erika\| Suganami, Yu\| Kishida, Masayuki\| Sugiyama, Hitoshi\| Okada, Hiroyuki\| Wada, Jun\|
抄録	Eight years prior to her present admission, a 61-year-old Japanese woman was diagnosed with autoimmune hepatitis, slowly progressive insulin-dependent diabetes mellitus, and chronic thyroiditis; she had been treated with oral prednisolone (PSL). After she suddenly discontinued PSL, she newly developed systemic lupus erythematosus. A combination therapy of oral PSL and intravenous cyclophosphamide resulted in remission. She was finally diagnosed with autoimmune polyglandular syndrome (APS) type 3 (3A ,3B, 3D), complicated with four different autoimmune diseases. Since patients with type 3 APS may present many manifestations over a long period of time, they should be carefully monitored.
キーワード	autoimmune polyglandular syndrome type 3 systemic lupus erythematosus autoimmune hepatitis slowly progressive insulin-dependent diabetes mellitus chronic thyroiditis
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2019-08
巻	73巻
号	4号
出版者	Okayama University Medical School
開始ページ	367
終了ページ	372
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31439961

Evaluation of Treatment Response in Prostate Cancer and Renal Cell Carcinoma Patients Using 11C-choline PET/CT Findings

JaLCDOI	10.18926/AMO/56936
フルテキストURL	73_4_341.pdf
著者	Kitajima, Kazuhiro\| Yamamoto, Shingo\| Nakanishi, Yukako\| Yamada, Yusuke\| Hashimoto, Takahiko\| Suzuki, Toru\| Go, Shuken\| Kanematsu, Akihiro\| Nojima, Michio\| Fujiwara, Masayuki\| Kaida, Hayato\| Tsurusaki, Masakatsu\| Kanda, Tomonori\| Tamaki, Yukihisa \| Yamakado, Koichiro\|
抄録	We investigated the effectiveness of 11C-choline-positron emission tomography/computed tomography (PET/CT) for evaluating treatment response in patients with prostate cancer or renal cell carcinoma. We performed 34 11C-choline PET/CT scans before/after a combined total of 17 courses of treatment in 6 patients with prostate cancer and 2 with renal cell carcinoma. The 17 treatments including hormonal therapy, radiotherapy, chemotherapy, radium-223, molecular target therapy, radiofrequency ablation, transcatheter arterial embolization, and cancer immunotherapy yielded 1 (5.9%) complete metabolic response (CMR), 3 (17.6%) partial metabolic responses (PMRs), 2 (11.8%) stable metabolic diseases (SMDs), and 11 (64.7%) progressive metabolic diseases (PMDs). Target lesions were observed in bone (n=14), lymph nodes (n=5), lung (n=2), prostate (n=2), and pleura (n=1), with CMR in 4, PMR in 10, SMD in 8 and PMD in 2 lesions. SUVmax values of the target lesions before and after treatment were 7.87±2.67 and 5.29±3.98, respectively, for a mean reduction of −35.4±43.6%. The response for the 8 prostate cancer-treatment courses was PMD, which correlated well with changes in serum prostatic specific antigen (PSA) (7 of 8 cases showed increased PSA). 11C-choline-PET/CT may be an effective tool for detecting viable residual tumors and evaluating treatment response in prostate cancer and renal cell carcinoma patients.
キーワード	treatment response 11C-choline PET/CT prostate cancer renal cell carcinoma
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-08
巻	73巻
号	4号
出版者	Okayama University Medical School
開始ページ	341
終了ページ	347
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31439957