検索結果 13726 件
| 著者 | 村田 厚生| 高橋 里奈| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | 村田 厚生| 平松 靖隆| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | 村田 厚生| 西嶋 和之| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | 村田 厚生| 山口 智司| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | 村田 厚生| 森若 誠| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | Ghazalli Zakri| 村田 厚生| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | Wang Shuguang| 村田 厚生| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | Hasuike Takashi| Ishii Hiroaki| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | Hanaa, E.Sayed| Hossam, A.Gabbar| Soheir, A. Fouadc| Khalil, M. Ahmedc| Miyazaki, Shigeji| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | Hanaa, E.Sayed| Hossam, A.Gabbar| Miyazaki, Shigeji| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | 半田 久志| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | Matsui Takeshi| Sakawa Masatoshi| Kato Kosuke| Matsumoto Koichi| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | Hara Akira| Yamaguchi Tomohisa| Ichimura Takumi| Takahama Tetsuyuki| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| 著者 | Mera Kazuya| Ichimura Takumi| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| JaLCDOI | 10.18926/14789 |
|---|---|
| タイトル（別表記） | IgE系アレルギー反応はアトピー型気管支喘息の白血球ロイコトリエンB4（LTB4）およびC4（LTC4）産生を促進させ，喫煙は気道過敏性を亢進させる |
| フルテキストURL | 74_042_047.pdf |
| 著者 | 芦田 耕三| 光廷 文裕| 保崎 泰弘| 岩垣 尚史| 永田 拓也| 藤井 誠| 高田 真吾| 横井 正| 浜田 全紀| 谷崎 勝朗| |
| 抄録 | Influences of IgE-mediated allergy and cigarette smoking on pathophysiology, evaluated by bronchial hyperresponsiveness and the generation of LTB4 and LTC4, of asthma were examined in 69 patients with asthma sensitive to inhalant allergens such as house dust mite and Candida albicans.
1 . Bronchial byperresponsiveness was significantly higher in previous and current smokers of asthmatics than in never-smokers. 2 . The generation of leukotrienes 84 (LTB4) and C4 (LTC4) by leucocytes was significantly larger in patients with serum IgE over 350 IU/ml than in those with serum IgE less than 150 IU/ml (LTB4 : p |
| キーワード | lgE-mediated allergy bronchial hyperresponsiveness LTB4 LTC4 asthma cigarette smoking |
| 出版物タイトル | 岡大三朝医療センター研究報告 |
| 発行日 | 2004-02-01 |
| 巻 | 74巻 |
| 開始ページ | 42 |
| 終了ページ | 47 |
| ISSN | 1348-1258 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308637 |
| JaLCDOI | 10.18926/14787 |
|---|---|
| フルテキストURL | 74_026_034.pdf |
| 著者 | 光廷 文裕| 保崎 泰弘| 芦田 耕三| 岩垣 尚史| 永田 拓也| 藤井 誠| 高田 真吾| 横井 正| 浜田 全紀| 谷崎 勝朗| |
| 抄録 | To determine the characteristics of the elderly in high - resolution computed tomography (HRCT) lung densitometry, mean lung density (MLD) and relative area of the lungs showing attenuation values less than -950 HU (RA(950)) on HRCT were evaluated in nonsmoking control subjects (n = 80) and patients with asthma (n = 80) in relation to their age and pulmonary function. MLD was significantly decreased, and RAW was significantly increased with increasing age in both asthmatics and controls. The MLD values were significantly lower in asthmatics compared with controls in subjects aged between 60 and 69 years and over age 70. RAgsov alues were significantly higher in asthmatics compared with controls in subjects aged between 50 and 59 years, between 60 and 69, and over 70. % FEV(1) and FEV(1) / FVC were significantly decreased in elderly asthmatic patients over 70 years of age compared with the values in those under 49. Percent residual volume (% RV) was significantly larger in patients over 70 years of age than in those between 50 and 59, and under 49 years. RAW was significantly larger in patients with steroid-dependent intractable asthma (SDIA) between 50 and 59 years of age, and between 60 and 69 compared with RA 950 in those without SDIA. However, RAW did not differ significantly between SDIA and non-SDIA in patients over age 70. The results suggested that in % LAA of the lungs on HRCT was significantly increased in the elderly subjects with and without asthma, and it was significantly higher in the elderly asthmatics than the elderly controls. |
| キーワード | aging (加齢) high-resolution computed tomography (高分解能CT) low attenuation area (低吸収域) mean lung density (平均CT値) pulmonary function (肺機能) |
| 出版物タイトル | 岡大三朝医療センター研究報告 |
| 発行日 | 2004-02-01 |
| 巻 | 74巻 |
| 開始ページ | 26 |
| 終了ページ | 34 |
| ISSN | 1348-1258 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308286 |
| JaLCDOI | 10.18926/14783 |
|---|---|
| フルテキストURL | 74_011_017.pdf |
| 著者 | 光延 文裕| 保崎 泰弘| 芦田 耕三| 岩垣 尚史| 永田 拓也| 藤井 誠| 高田 真吾| 横井 正| 浜田 全紀| 谷崎 勝朗| |
| 抄録 | Clinical effects of long-term spa therapy for 4 years were estimated in 8 patients of pulmonary emphysema (4 with spa therapy and 4 without spa therapy) by pulmonary function and morphological changes of peripheral airspaces of the lung on
high - resolution computed tomography (HRCT).
1 . The values of % FVC, % FEV1.0, and FEV 1.0% did not significantly change for 4year observation both in patients with spa therapy and those without spa therapy.
2. The OLco value significantly decreased from 69.9% at the initial level to 48.8% after 4-year observation in patients without spa therapy (p |
| キーワード | spa therapy (温泉療法) pulmonary emphysema (,肺気腫) % RV % DLco % low attenuation area of the lung |
| 出版物タイトル | 岡大三朝医療センター研究報告 |
| 発行日 | 2004-02-01 |
| 巻 | 74巻 |
| 開始ページ | 11 |
| 終了ページ | 17 |
| ISSN | 1348-1258 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308395 |
| 著者 | Milan Vlach| |
|---|---|
| 発行日 | 2008-12 |
| 出版物タイトル | Proceedings : Fourth International Workshop on Computational Intelligence & Applications |
| 巻 | 2008巻 |
| 号 | 1号 |
| 資料タイプ | 会議発表論文 |
| JaLCDOI | 10.18926/14773 |
|---|---|
| タイトル（別表記） | ’あくび’と胸痛を訴えた気管支喘息の1症例 |
| フルテキストURL | 73_081_083.pdf |
| 著者 | 光延 文裕| 芦田 耕三| 保崎 泰弘| 柘野 浩史| 岡本 誠| 西田 典数| 永田 拓也| 高田 真吾| 谷崎 勝朗| |
| 抄録 | We present a case of a patient with asthma who developed yawning associated with anterior chest pain. She was admitted due to severe anterior chest pain, wheezing and dyspnea. Although the frequency of the symptoms decreased, she began to experience frequent episodes of yawning at night accompanied by tears. While she experienced yawning, although PEF (peak expiratory flow) decreased, no asthmatic symptoms, such as wheezing or dyspnea were observed. The yawning was improved markedly by bronchodilators and a leukotriene receptor antagonist, and moderately improved by corticosteroids. We speculated that yawning is a clinical manifestation of asthma that responds to treatment. |
| キーワード | yawning chest pain nocturnal dyspnea asthma |
| 出版物タイトル | 岡大三朝医療センター研究報告 |
| 発行日 | 2003-02-01 |
| 巻 | 73巻 |
| 開始ページ | 81 |
| 終了ページ | 83 |
| ISSN | 1348-1258 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308373 |
| JaLCDOI | 10.18926/14771 |
|---|---|
| タイトル（別表記） | 食道痛細胞におけるWntのベータカテ二ンTCF経路の活性化の検討 |
| フルテキストURL | 73_075_080.pdf |
| 著者 | 水島 孝明| 越智 浩二| 江盛 康之| 谷岡 洋亮| 澤 公成| 藤岡 真一| 真治 紀之| 小出 典男| 谷崎 勝朗| |
| 抄録 | Although, accumulation of nuclear and cytoplasmic beta-catenin has been observed in ESCCs, mutation of APC and beta-catenin are not found in ESCCs. Therefore, another mechanism for cytoplasmic beta- catenin accumulation might exist in ESCCs. Materials and Methods: Human ESCCs cell lines and the 293 stable transfectants expressing Wnt-1, Wnt-5A, and Wnt-7A were cultured under standard conditions. The TOPFlash or FOPFlash reporter plasmids were transfected. Results: Transfected mutant beta-catenin as well as an axin fragment harbing the GSK3 beta interaction domain, the latter a potent GSK3 beta inhibitor. both robustly activated pTOPFlash in ESCCs cells. When pTOPFlash/pFOPFlash reporters were transfected in ESCCs cell lines followed by cocultivation with 293 cells that stably express Wnt -1, all cell lines except one demonstrated TCF mediated transcriptional. But, cells were co- cultured, Wnt - 7A or Wnt - 5A did not activate TCF mediated transcription in a cell number dependent fashion. Discussion; We report the activation of TCF promoter gene by extemal Wnt stimuli in ESCCs cells. |
| キーワード | esophageal carcinoma Wnt TCF beta-catenin |
| 出版物タイトル | 岡大三朝医療センター研究報告 |
| 発行日 | 2003-02-01 |
| 巻 | 73巻 |
| 開始ページ | 75 |
| 終了ページ | 80 |
| ISSN | 1348-1258 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120002308224 |