検索結果 2527 件
| JaLCDOI | 10.18926/AMO/54003 |
|---|---|
| フルテキストURL | 70_1_45.pdf |
| 著者 | Maruyama, Hidehiko| Nakata, Yusei| Kanazawa, Akane| Kikkawa, Kiyoshi| |
| 抄録 | Mothers of preterm infants may find it difficult to express breast milk. There is a low breast milk rate among preterm infants at discharge at our hospital, and here we tested the hypothesis that milk expression factors were the cause of the low rate. The study subjects were born before 33 gestational weeks at our hospital between March 2005 and June 2014. Nutritional evaluation was performed at discharge and noted whether breast milk, infant formula, or a mix of the 2 was being given. We compared the group given breast milk or the mix versus the group given formula. Of the 337 infants, 40 cases were excluded. Data from 297 infants were analyzed. The mean (SD) gestational age and birth weight were 29.5 (2.4) weeks and 1,230 (391) g, respectively. At discharge, 26 (8.8%), 102 (33.3%), and 174 (57.9%) infants were given breast milk, formula, and the mix, respectively. A multivariate logistic regression analysis showed that the first milk expression (h) was the risk factor for the formula group: adjusted odds ratio (95% confidence interval) 1.06 (1.02-1.09) and p=0.002. Delayed first milk expression could affect the low breast milk rate at discharge. Improvement of milk expression should be achieved to promote breastfeeding. |
| キーワード | breast milk breastfeeding formula milk expression preterm |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-02 |
| 巻 | 70巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 45 |
| 終了ページ | 49 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26899609 |
| Web of Science KeyUT | 000371288700006 |
| JaLCDOI | 10.18926/AMO/53996 |
|---|---|
| フルテキストURL | 70_1_1.pdf |
| 著者 | Yasunaka, Tetsuya| Ikeda, Fusao| Wada, Nozomu| Morimoto, Yuki| Fujioka, Shin-ichi| Toshimori, Junichi| Kobashi, Haruhiko| Kariyama, Kazuya| Morimoto, Yoichi| Takayama, Hiroki| Seno, Tomonori| Takaguchi, Koichi| Moriya, Akio| Miyatake, Hirokazu| Okamoto, Ryoichi| Yabushita, Kazuhisa| Takaki, Akinobu| Yamamoto, Kazuhide| |
| 抄録 | Chronic hepatitis B (CHB) leads to cirrhosis and hepatocellular carcinoma (HCC). With a cohort of 1,206 CHB patients who visited Okayama University Hospital and related hospitals in 2011 and 2012, we compared the incidence rates of HCC among the patients grouped by age, hepatitis B virus (HBV) DNA, hepatitis B e antigen (HBeAg), and treatment. HCCs were observed in 115 patients with the median observation period of 1,687 days. Among the HCC patients aged ≥ 35 years, HBV DNA ≥ 4 log copies/mL and positive HBeAg at diagnosis (n=184), the HCC incidence rate was 8.4% at 5 years in the entecavir (ETV)-treated patients, 21.8% in the lamivudine (LVD)-treated patients, and 26.4% among the patients not treated with drugs. The cumulative HCC incidence was significantly reduced in the ETV-treated patients compared to those treated with LVD or not treated (p=0.013). Among the patients aged ≥ 35 years with HBV DNA ≥ 4 log copies/mL and negative HBeAg (n=237), the cumulative HCC incidence was 14.6% in 5 years in ETV group and 13.9% among those not treated with a drug (p>0.05). Only small numbers of HCCs occurred in other patients. In CHB patients aged≥35 years with HBV DNA ≥4 log copies/mL and positive HBeAg, ETV treatment is recommended for the suppression of HCC development. |
| キーワード | entecavir hepatitis B virus lamivudine hepatocellular carcinoma |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-02 |
| 巻 | 70巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 1 |
| 終了ページ | 12 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26899604 |
| Web of Science KeyUT | 000371288700001 |
| JaLCDOI | 10.18926/AMO/53908 |
|---|---|
| フルテキストURL | 69_6_339.pdf |
| 著者 | Senoo, Miki| Nakatsuka, Mikiya| |
| 抄録 | Pregnant women with uterine leiomyomas may experience anxiety toward their pregnancies and unfavorable feelings toward their infants. From March to July 2010, we distributed anonymous self-recorded questionnaires to 200 pregnant women who visited Okayama Central Hospital for an antenatal check-up after informed consent was provided, and 132 women (23 pregnant women with uterine leiomyomas) were included in our study. Among the multiparous women in their first trimester, the women with uterine leiomyomas had a higher rate of anxiety than those without uterine leiomyomas. ʻAvoidanceʼ scores on the Feeling Toward the Baby Scale were significantly higher in the leiomyoma group. The conflict index scores tended to be higher in the leiomyoma group. A multivariate analysis revealed no factors associated with trait-anxiety scores, whereas high state-anxiety scores were correlated with low age;however, there was no correlation between these scores and uterine leiomyomas. Although no factors were associated with State-Trait Anxiety Inventory (STAI) and approach scores toward the baby, avoidance and conflict index scores were associated with the existence of uterine leiomyomas. In pregnant women with uterine leiomyomas, efforts should be made to reduce anxiety in the first trimester, and support should be provided to help these women develop positive feelings toward their babies. |
| キーワード | pregnancy uterine leiomyomas anxiety feelings toward the baby pregnancy loss |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-12 |
| 巻 | 69巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 339 |
| 終了ページ | 348 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26690244 |
| Web of Science KeyUT | 000368434500003 |
| 関連URL | http://doi.org/10.18926/AMO/54008 |
| JaLCDOI | 10.18926/AMO/53907 |
|---|---|
| フルテキストURL | 69_6_333.pdf |
| 著者 | Ito, Maiko| Shien, Tadahiko| Kaji, Mitsumasa| Mizoo, Taeko| Iwamoto, Takayuki| Nogami, Tomohiro| Motoki, Takayuki| Taira, Naruto| Doihara, Hiroyoshi| Miyoshi, Shinichiro| |
| 抄録 | We evaluated the usefulness of preoperative 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) examinations to predict the pathological features in primary breast cancer. In particular, we evaluated the correlation between the maximum standardized uptake values (SUVmax) obtained by 18F-FDG PET/CT and the Ki67 expression in estrogen receptor (ER)-positive invasive ductal carcinoma (IDC). Primary IDC patients operated between March 2009 and July 2013 at Okayama University Hospital were enrolled. We evaluated the correlations between the SUVmax and age, postoperative pT, histological grade, lymph vascular invasion, status of hormone receptor, human epidermal growth factor receptor 2 (HER2), Ki67 expression and node status. The Ki67 expression was classified as high (>14%) versus low (<14%). We enrolled 138 patients with IDC. Their median SUVmax was 3.85 (range:0-52.57). In a univariate analysis, the SUVmax was significantly related to age, pT, histological grade, lymphovascular invasion, hormone receptor status, HER2 status, node status and Ki67. In the 113 patients with ER-positive IDC, there was a significant correlation between Ki67 and SUVmax (p=0.0030). The preoperative 18F-FDG PET/CT results of IDC patients had significant relationships with pathological status parameters. The determination of the preoperative SUVmax might help classify Luminal A and Luminal B patients among luminal-type breast cancer patients. |
| キーワード | breast cancer invasive ductal carcinoma 18F-fluorodeoxyglucose positron emission tomography/computed tomography maximum standardized uptake values clinicopathological features |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-12 |
| 巻 | 69巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 333 |
| 終了ページ | 338 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26690243 |
| Web of Science KeyUT | 000368434500002 |
| 著者 | 長谷川 芳典| |
|---|---|
| 発行日 | 2001-12-03 |
| 出版物タイトル | 岡山大学文学部紀要 |
| 巻 | 36巻 |
| 資料タイプ | 紀要論文 |
| JaLCDOI | 10.18926/okadai-bun-kiyou/53867 |
| タイトル（別表記） | Non-high-output cardiac failure in patients undergoing hemodialysis through an arteriovenous shunt |
|---|---|
| フルテキストURL | 127_203.pdf |
| 著者 | 鵜川 豊世武| |
| 抄録 | Background: Hemodialysis-related heart failure has been considered to be associated with excessive blood flow through the arteriovenous (AV) shunt used for vascular access. However, some patients undergoing dialysis have heart failure in the absence of an increase in cardiac output (CO) related to shunt blood-flow loading because the loading cannot be compensated for by increasing CO. This condition may be challenging to manage ; thus, early diagnosis is important. Methods and Results: Twelve patients (mean age, 71 years ; 9 men) with end-stage renal disease, dialysis-related heart failure, a high brain natriuretic peptide (BNP) level, and a mean New York Heart Association (NYHA) class of II underwent AV shunt closure. Their cardiac index (CI), pre- and post-dialysis BNP levels, and several cardiac variables were assessed pre- and postoperatively. All patients achieved relief of heart failure symptoms and a reduction in NYHA class after AV closure, but six patients had a postoperative increase in CI (the "non-high-output" cardiac failure group), whereas the other six had a decrease in CI (the "high-output" cardiac failure group). The high-output patients had greater improvements in BNP levels and most cardiac variables compared to the non-high-output group ; therefore, the heart failure in the non-high-output patients was considered more serious than that in the high-output group. Conclusions: The selection of effective strategies for treating dialysis-related heart failure may depend partly on identifying which patients have non-high-output failure. Such identification requires serial measurements of BNP levels and evaluations of cardiac variables other than the ejection fraction. |
| キーワード | 心拍出量（cardiac output） 心不全（heart failure） 脳性ナトリウム利尿ペプチド（brain natriuretic peptide） 非過大シャント心不全（non-high-output cardiac failure） 腎臓（kidney） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2015-12-01 |
| 巻 | 127巻 |
| 号 | 3号 |
| 開始ページ | 203 |
| 終了ページ | 207 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.127.203 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2015 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.127.203 |
| NAID | 130005116810 |
| タイトル（別表記） | Basic and clinical research regarding vascular endothelial function |
|---|---|
| フルテキストURL | 127_187.pdf |
| 著者 | 塚原 宏一| |
| キーワード | アルギニン代謝 一酸化窒素 ガス生物学 血管内皮学 酸化ストレス |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2015-12-01 |
| 巻 | 127巻 |
| 号 | 3号 |
| 開始ページ | 187 |
| 終了ページ | 195 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2015 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.127.187 |
| NAID | 130005116819 |
| JaLCDOI | 10.18926/AMO/53673 |
|---|---|
| フルテキストURL | 69_5_275.pdf |
| 著者 | Nosaka, Nobuyuki| Goda, Yu| Knaup, Emily| Tsukahara, Kohei| Yumoto, Tetsuya| Ugawa, Toyomu| Ujike, Yoshihito| |
| 抄録 | We sought to identify the incidence, injury patterns, and financial burden of ladder fall injuries to provide a reference for reinforcing guidelines on the prevention of such injuries. We enrolled the patients who were injured in a ladder-related fall and required intensive care between April 2012 and March 2014 at Okayama University Hospital, a tertiary care hospital in Okayama City:9 patients injured in 7 stepladder falls and 2 straight ladder falls. The median patient age was 69 years, and 8 were males. Six falls occurred in non-occupational settings. Head injuries predominated, and the injury severity score ranged from 2 to 35 (mean＝21±12). At the time of discharge from the intensive care unit, one patient had died and 5 patients had some neurological disabilities. The case fatality rate was 11%. The total cost of care during the review period was ￥16,705,794, with a mean cost of ￥1,856,199 per patient. Ladder fall injuries are associated with a high rate of neurological sequelae and pose a financial burden on the health insurance system. A prevention education campaign targeting at older-aged males in non-occupational settings may be a worthwhile health service investment in this community. |
| キーワード | accidental falls accident prevention hospital costs injuries ladder |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-10 |
| 巻 | 69巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 275 |
| 終了ページ | 278 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26490024 |
| Web of Science KeyUT | 000365519600003 |
| JaLCDOI | 10.18926/AMO/53672 |
|---|---|
| フルテキストURL | 69_5_267.pdf |
| 著者 | Inada, Ryo| Nagasaka, Takeshi| Kondo, Yoshitaka| Watanabe, Ayako| Toshima, Toshiaki| Kubota, Nobuhito| Kikuchi, Satoru| Ishida, Michihiro| Kuroda, Shinji| Mori, Yoshiko| Kishimoto, Hiroyuki| Fujiwara, Toshiyoshi| |
| 抄録 | The aim of this single-institution, retrospective, observational case-control study was to evaluate the safety and feasibility of laparoscopic proctocolectomy (PC) for ulcerative colitis (UC), by comparing it with a case-control series of open PC. Twenty UC patients who underwent laparoscopic PC were retrospectively compared with the open PC group of 12 patients matched for age, sex, and urgency of the operation. In the laparoscopic PC group, the operative time was significantly longer, but the amount of blood loss was significantly smaller. The open PC patients underwent an intraoperative blood transfusion significantly more often, and the serum C-reactive protein level on the first postoperative day was significantly higher in the open PC group. In the laparoscopic PC group, the rate of severe postoperative morbidities, grades 3 and 4 on the Clavien-Dindo classification, was significantly lower, and the median length of hospital stay was significantly shorter. Laparoscopic PC for patients with UC showed superior perioperative outcomes to open PC, except for longer operative time. |
| キーワード | laparoscopic surgery total proctocolectomy open proctocolectomy ulcerative colitis case-matched study |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-10 |
| 巻 | 69巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 267 |
| 終了ページ | 273 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26490023 |
| Web of Science KeyUT | 000365519600002 |
| JaLCDOI | 10.18926/AMO/53671 |
|---|---|
| フルテキストURL | 69_5_261.pdf |
| 著者 | Nojima, Daisuke| Fujimoto, Nobukazu| Kato, Katsuya| Fuchimoto, Yasuko| Kiura, Katsuyuki| Kishimoto, Takumi| Tanimoto, Mitsune| |
| 抄録 | We investigated the clinical features of asbestos-induced diffuse pleural thickening (DPT) with severe respiratory compromise. We conducted a retrospective study of consecutive subjects with asbestos-induced DPT. Medical data such as initial symptoms, radiological findings, respiratory function test results, and clinical course were collected and analyzed. There were 24 patients between 2003 and 2012. All were men, and the median age at the development of DPT was 74 years. The top occupational category associated with asbestos exposure was dockyard workers. The median duration of asbestos exposure was 35.0 years, and the median latency from first exposure to the onset of DPT was 49.0 years. There were no significant differences in respiratory function test results between the higher and lower Brinkman index groups or between unilateral and bilateral DPT. Thirteen patients had a history of benign asbestos pleural effusion (BAPE), and the median duration from pleural fluid accumulation to DPT with severe respiratory compromise was 28.4 months. DPT with severe respiratory compromise can develop after a long latency following occupational asbestos exposure and a history of BAPE. |
| キーワード | asbestos pleural thickening MRC dyspnea scale respiratory function test costophrenic angle |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-10 |
| 巻 | 69巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 261 |
| 終了ページ | 266 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26490022 |
| Web of Science KeyUT | 000365519600001 |
| 著者 | Aoba, Kana| Matsuo, Toshihiko| Hamasaki, Ichiro| Hasebe, Kayoko| |
|---|---|
| 発行日 | 2015-04-07 |
| 出版物タイトル | SpringerPlus |
| 巻 | 4巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Matsuo, Toshihiko| |
|---|---|
| 発行日 | 2014-07-16 |
| 出版物タイトル | SpringerPlus |
| 巻 | 3巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Matsuo, Toshihiko| |
|---|---|
| 発行日 | 2015-09-21 |
| 出版物タイトル | SpringerPlus |
| 巻 | 4巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Matsuo, Toshihiko| |
|---|---|
| 発行日 | 2015-08-28 |
| 出版物タイトル | SpringerPlus |
| 巻 | 4巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Ryosuke, Nakato| Yu, Ohkubo| Akari, Konishi| Mari, Shibata| Yuki, Kaneko| Takao, Iwawaki| Tomohiro, Nakamura| Stuart A., Lipton| Takashi, Uehara| |
|---|---|
| 発行日 | 2015 |
| 出版物タイトル | Scientific Reports |
| 巻 | 5巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Tsuda, Toshihide| Tokinobu, Akiko| Yamamoto, Eiji| Suzuki, Etsuji| |
|---|---|
| 発行日 | 2015 |
| 出版物タイトル | Epidemiology |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Wu, Yi-Bing| Liu, Dan| Liu, Pei-Yu| Yang, Xue-Mei| Liao, Man| Lu, Nan-Nan| Sauriol, FranÅoise| Gu, Yu-Cheng| Shi, Qing-Wen| Kiyota, Hiromasa| Dong, Mei| |
|---|---|
| 発行日 | 2015-05-26 |
| 出版物タイトル | Helvetica Chimica Acta |
| 巻 | 98巻 |
| 号 | 5号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/53558 |
|---|---|
| フルテキストURL | 69_4_219.pdf |
| 著者 | Toshimori, Junichi| Nouso, Kazuhiro| Nakamura, Shinichiro| Wada, Nozomu| Morimoto, Yuki| Takeuchi, Yasuto| Yasunaka, Tetsuya| Kuwaki, Kenji| Ohnishi, Hideki| Ikeda, Fusao| Shiraha, Hidenori| Takaki, Akinobu| Yamamoto, Kazuhide| |
| 抄録 | We conducted a retrospective cohort study to investigate the predisposing factors for local recurrence and complications after percutaneous radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC). HCC patients (n＝397) consecutively treated with RFA (256 males, 141 females, median age 69 years) were enrolled. In these patients, 1,455 nodules (median size 17mm) were ablated. Predisposing factors for overall recurrence and local recurrence in the context of tumor location and complications were examined. Local recurrence was observed for 113 of the 1,455 nodules. The 1-, 3- and 5-year local recurrence rates were 2.2ｵ, 7.4ｵ and 9.5ｵ, respectively. A multivariate Cox proportional hazard analysis revealed that large tumor size (＞2cm), tumor location (adjacent to the major portal branch or hepatic vein), and small ablated margin (＜3mm) were independent predisposing factors for local recurrence after RFA (HR＝1.70-2.81). Tumor location (adjacent to the major portal branch, hepatic vein, or diaphragm) was also revealed as a risk factor for liver damage due to RFA. HCC adjacent to the major portal vein or hepatic vein was associated with a higher risk for local recurrence and for complications;therefore, special precautions are necessary when applying RFA to HCC near vessels even when the tumors are located at an easy-to-puncture site. |
| キーワード | hepatocellular carcinoma radiofrequency ablation ablated margin tumor location |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-08 |
| 巻 | 69巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 219 |
| 終了ページ | 226 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26289913 |
| Web of Science KeyUT | 000365519100005 |
| タイトル（別表記） | Role of COLXV/XVⅢ gene, Multiplexin, as a basement membrane toolkit |
|---|---|
| フルテキストURL | 127_103.pdf |
| 著者 | 大橋 俊孝| |
| キーワード | 基底膜 ツールキット XV/XVⅢ型コラーゲン プロテオグリカン ミトコンドリア |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2015-08-03 |
| 巻 | 127巻 |
| 号 | 2号 |
| 開始ページ | 103 |
| 終了ページ | 109 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.127.103 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2015 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.127.103 |
| NAID | 130005096251 |
| JaLCDOI | 10.18926/AMO/53522 |
|---|---|
| フルテキストURL | 69_3_155.pdf |
| 著者 | Mikamo, Shoko| Nakatsuka, Mikiya| |
| 抄録 | To assess the knowledge and attitudes of pregnant Japanese women regarding non-invasive prenatal testing (NIPT). Between March and June 2013, 557 pregnant women in the Hyogo and Hiroshima Prefectures were surveyed using an anonymous, self-completed questionnaire. A total of 91.9ｵ respondents (512/557) stated that they “agree” or “conditionally agree” with NIPT implementation in Japan. Approximately 28.5ｵ of respondents stated that they knew that the accuracy of a positive NIPT result can be affected by motherʼs age and background, while 34.5ｵ of respondents stated that it was necessary for pregnant women with a positive result to undergo fetal chromosome diagnosis using amniocentesis;both percentages were low. Additionally, 92.3ｵ of respondents would “like a detailed explanation of the test,” 65.1ｵ of them would “like psychological support if the NIPT test results came back positive,” and 5.7ｵ would terminate the pregnancy if the NIPT test results came back positive without undergoing fetal chromosome diagnosis via amniocentesis. Although a high proportion of pregnant Japanese women agreed with the introduction of NIPT into Japanese obstetrical care, there was insufficient knowledge regarding the test. It is necessary for women undergoing NIPT to be provided sufficient information and psychological support. |
| キーワード | amniocentesis Down syndrome fetal chromosome diagnosis non-invasive prenatal testing psychological support |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 155 |
| 終了ページ | 163 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101191 |
| Web of Science KeyUT | 000356903000004 |