検索結果 1399 件
| タイトル（別表記） | A refractory cutaneous-rectovesical fistula complicated with abdominal actinomycosis successfully treated with antibiotic therapy |
|---|---|
| フルテキストURL | 129_35.pdf |
| 著者 | 桂 佑貴| 松川 啓義| 加藤 卓也| 杉原 正大| 小島 康知| 塩崎 滋弘| |
| 抄録 | The patient was a 35-year-old Japanese man diagnosed with appendicitis with abscess formation. An appendectomy was performed, but a refractory surgical wound infection developed, and eventually a cutaneous-rectovesical fistula was detected. In a review of the first-time CT scan, a small high-density construction resembling a bone from a fish was detected in the ileum. The histopathological examination revealed granules of actinomyces. These findings suggested that abdominal actinomycosis due to intestinal mucosal breakage by the fish bone caused the secondary appendicitis, and that after the appendectomy, residual actinomyces caused the cutaneous-rectovesical fistula. After the diagnosis, total parenteral nutrition and a long-term administration of antibiotics improved the patient's clinical symptoms, and the fistula closed within a month. Antibiotics were administered for 6 months, and there has been no recurrence for 6-1/2 years. Because actinomycosis is difficult to diagnose based on the typical clinical features, a direct identification of the infecting organism from a tissue sample or from sulfur granules is required for the definitive diagnosis. Actinomyces is also known to cause fistula formation, and intestinal penetration caused by a fish bone may indicate abdominal actinomycosis. A rectovesical fistula requires surgical intervention in most cases, but in cases caused by abdominal actinomycosis, such a fistula may be cured by conservative therapy, as in our patient's case. It is important to consider the possibility of actinomycosis when a refractory rectovesical fistula is observed. |
| キーワード | 放線菌症 (actinomycosis) 皮膚直腸膀胱瘻 (cutaneous-rectovesical fistula) 急性虫垂炎 (appendicitis) |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2017-04-03 |
| 巻 | 129巻 |
| 号 | 1号 |
| 開始ページ | 35 |
| 終了ページ | 39 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2017 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.129.35 |
| NAID | 130005632060 |
| JaLCDOI | 10.18926/OLR/54889 |
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| タイトル（別表記） | Several Points of Issue on the Informed Consent-An Analysis of a Model Case from the Aspect of Comparative Law |
| フルテキストURL | olr_018_015_046.pdf |
| 著者 | 山下 登| |
| 出版物タイトル | 臨床法務研究 |
| 発行日 | 2017-03 |
| 巻 | 18巻 |
| 開始ページ | 15 |
| 終了ページ | 46 |
| ISSN | 1881-1485 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120006026943 |
| フルテキストURL | K0005394_abstract_review.pdf K0005394_fulltext.pdf |
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| 著者 | 山下 美保| |
| 発行日 | 2016-09-30 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5394号 |
| 学位授与年月日 | 2016-09-30 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| 著者 | 小橋 研太| 石井 博| 西山 加那子| 松三 雄騎| 羽田野 雅英| 藤原 雅光| 黒河 達雄| 常光 謙輔| |
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| 発行日 | 2016-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 128巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 水川 展吉| 小野田 友男| 松本 洋| 武田 斉子| 野田 洋平| 小野田 聡| 福島 麻衣| 津村 宗近| 竹内 哲男| 杉山 成史| 木股 敬裕| |
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| 発行日 | 2016-12-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 128巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| タイトル（別表記） | A case of mucinous adenocarcinoma of the duodenum and literature review of 16 cases reported in Japan |
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| フルテキストURL | 128_21.pdf |
| 著者 | 浜野 郁美| 松本 祐介| 遠藤 芳克| 渡邊 直樹| 甲斐 恭平| 佐藤 四三| 和仁 洋治| |
| 抄録 | Primary mucinous adenocarcinoma of the duodenum is rare. Here we report a case we recently encountered, and we review 16 cases reported in Japan. An 82-year-old Japanese woman was admitted to our hospital complaining of abdominal pain and heartburn. An endoscopic examination revealed a Type 2 tumor in the descending limb of the duodenum, and endoscopically obtained specimens revealed a poorly differentiated adenocarcinoma. We performed a curative pancreatoduodenectomy with lymph node resection, and the surgical specimen revealed that the duodenum was the primary site of the mucinous adenocarcinoma. The patient is currently alive ＞ 1 year after the operation without any evidence of recurrence. Of the 16 patients reviewed, all patients had advanced tumors those depth were T3-T4. 9 patients had lymph node metastasis and 4 patients had peritoneal dissemination at the time of surgery. Since mucinous adenocarcinoma of the duodenum is often progressive cancer at a diagnosis, which is tend to have a worse prognosis than other histological types. |
| キーワード | 原発性十二指腸癌（primary duodenal cancer） 粘液癌（mucinous carcinoma） 膵頭十二指腸切除（pancreatoduodenectomy） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2016-04-01 |
| 巻 | 128巻 |
| 号 | 1号 |
| 開始ページ | 21 |
| 終了ページ | 25 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.128.21 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2016 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.128.21 |
| NAID | 130005149602 |
| 著者 | 鐸木 道剛| |
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| 発行日 | 1988-12 |
| 出版物タイトル | 岡山大学文学部紀要 |
| 巻 | 10巻 |
| 資料タイプ | 紀要論文 |
| JaLCDOI | 10.18926/okadai-bun-kiyou/53805 |
| 著者 | 鐸木 道剛| |
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| 発行日 | 1986-12 |
| 出版物タイトル | 岡山大学文学部紀要 |
| 巻 | 7巻 |
| 資料タイプ | 紀要論文 |
| JaLCDOI | 10.18926/okadai-bun-kiyou/53804 |
| 著者 | Nishiyama, Yuichi| Hanafusa, Tadashi| Yamashita, Jun| Yamamoto, Yoko| Ono, Toshiro| |
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| 発行日 | 2015-06-20 |
| 出版物タイトル | Journal of Radioanalytical and Nuclear Chemistry |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/53674 |
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| フルテキストURL | 69_5_279.pdf |
| 著者 | Saito, Yukie| Fujii, Yousuke| Yashiro, Masato| Tsuge, Mitsuru| Nosaka, Nobuyuki| Yamashita, Nobuko| Yamada, Mutsuko| Tsukahara, Hirokazu| Morishima, Tsuneo| |
| 抄録 | Lung hyperpermeability affects the development of acute respiratory distress syndrome (ARDS), but therapeutic strategies for the control of microvascular permeability have not been established. We examined the effects of edaravone, dexamethasone, and N-monomethyl-L-arginine (L-NMMA) on permeability changes in human pulmonary microvascular endothelial cells (PMVEC) under a hypercytokinemic state. Human PMVEC were seeded in a Boyden chamber. After monolayer confluence was achieved, the culture media were replaced respectively by culture media containing edaravone, dexamethasone, and L-NMMA. After 24-h incubation, the monolayer was stimulated with tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Fluorescein-labeled dextran was added. Then the trans-human PMVEC leak was measured. Expressions of vascular endothelial-cadherin (VE-cadherin) and zonula occludens-1 protein (ZO-1) were evaluated using real-time quantitative polymerase chain reaction and immunofluorescence microscopy. The results showed that TNF-α＋IL-1β markedly increased pulmonary microvascular permeability. Pretreatment with edaravone, dexamethasone, or L-NMMA attenuated the hyperpermeability and inhibited the cytokine-induced reduction of VE-cadherin expression on immunofluorescence staining. Edaravone and dexamethasone increased the expression of ZO-1 at both the mRNA and protein levels. Edaravone and dexamethasone inhibited the permeability changes of human PMVEC, at least partly through an enhancement of VE-cadherin. Collectively, these results suggest a potential therapeutic approach for intervention in patients with ARDS. |
| キーワード | pulmonary microvascular endothelial cells permeability edaravone vascular endothelial-cadherin zonula occludens-1 protein |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-10 |
| 巻 | 69巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 279 |
| 終了ページ | 290 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26490025 |
| Web of Science KeyUT | 000365519600004 |
| フルテキストURL | K0005195_abstract_review.pdf K0005195_fulltext.pdf |
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| 著者 | 山下 真子| |
| 発行日 | 2015-06-30 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5195号 |
| 学位授与年月日 | 2015-06-30 |
| 学位・専攻分野 | 博士（医学） |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| タイトル（別表記） | A case of laparoscopic and endoscopic cooperative surgery for sigmoidovesical fistula |
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| フルテキストURL | 127_123.pdf |
| 著者 | 加藤 大| 大石 正博| 小寺 正人| 山村 方夫| 池田 秀明| 水野 憲治| 谷 悠真| 山下 裕| 早田 俊司| 倉繁 拓志| 西山 康弘| 西川 大祐| |
| 抄録 | We performed laparoscopic and endoscopic cooperative surgery (LECS) for partial colectomy with partial cystectomy in an 80-year-old woman with sigmoidovesical fistula secondary to sigmoid diverticulitis. LECS was designed for local resection of the stomach for gastric submucosal tumors using the endoscopic submucosal dissection (ESD) technique. While conventional open abdominal surgery is very invasive, LECS has enabled surgeons to perform minimally invasive surgery. Although there have been no reported cases in which the bladder was laparoscopically resected after sigmoidovesical fistula division, we were able to safely resect the fistula and preserve the urethral opening by performing laparoscopic and cystoscopic cooperative surgery. There are no previously reported cases in which LECS was performed for partial sigmoidectomy and partial cystectomy ; therefore, we report this as a valuable case, with a review of the literature. We hope that further studies involving more patients will lead to the establishment of this procedure. |
| キーワード | 結腸膀胱瘻（sigmoidovesical fistula） 腹腔鏡内視鏡合同手術（laparoscopic and endoscopic cooperative surgery（LECS）） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2015-08-03 |
| 巻 | 127巻 |
| 号 | 2号 |
| 開始ページ | 123 |
| 終了ページ | 126 |
| ISSN | 0030-1558 |
| 関連URL | isVersionOf https://doi.org/10.4044/joma.127.123 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2015 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.127.123 |
| NAID | 130005096254 |
| 著者 | 山下 光治| 濱本 裕司| 安田 悠人| 小野 朋子| |
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| 発行日 | 2015-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 31巻 |
| 資料タイプ | 学術雑誌論文 |
| タイトル（別表記） | Laparoscopic total colectomy with lymph node dissection for familial adenomatous polyposis with multiple colorectal cancers |
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| フルテキストURL | 127_25.pdf |
| 著者 | 加藤 大| 大石 正博| 小寺 正人| 山村 方夫| 池田 秀明| 水野 憲治| 山下 裕| |
| 抄録 | A 49-year-old Japanese man visited our hospital with chief complaints of difficulty with and bleeding during defecation. After a detailed examination, he was diagnosed with familial adenomatous polyposis (FAP) with multiple (five) colorectal cancers. The tumors were located in the right-sided, left-sided, and sigmoid colon, and the lower rectum. Regional lymph node involvement was observed, but no metastasis to other organs was detected. We, therefore, performed a laparoscopic total colectomy with superior mesenteric artery (SMA) and inferior mesenteric artery (IMA) lymph node dissection. We were able to perform minimally invasive and cosmetically acceptable surgery using laparoscopy instead of highly-invasive open abdominal surgery. Our search of the literature revealed no reported cases of laparoscopic total colectomy with lymph node dissection for FAP with multiple colorectal cancers, making the present case the first to be reported in the literature. |
| キーワード | 家族性大腸腺腫症（FAP）（familial adenomatous polyposis） 同時性多発大腸癌（synchronous colorectal cancer） 大腸全摘術（colorectal surgery） 腹腔鏡下手術（laparoscopic surgery） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2015-04-01 |
| 巻 | 127巻 |
| 号 | 1号 |
| 開始ページ | 25 |
| 終了ページ | 29 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2015 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.127.25 |
| NAID | 130005068353 |
| タイトル（別表記） | Giant rectal gastrointestinal stromal tumor successfully resected by abdominoperineal resection combined with posterior vaginal wall resection |
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| フルテキストURL | 126_217.pdf |
| 著者 | 岩川 和秀| 西江 学| 徳永 尚之| 宮宗 秀明| 岩垣 博巳| |
| 抄録 | We report a case of giant rectal gastrointestinal stromal tumor (GIST) successfully resected by abdominoperineal resection combined with posterior vaginal wall resection. Our patient was a 79-year-old woman had been diagnosed as having von Recklinghausen disease at the age of 30 years. In 2006, a computed tomography (CT) scan revealed a tumor originating from the posterior wall of the rectum. In June 2010, she was admitted to our hospital with the chief complaint of bloody stool. A CT scan revealed a giant tumor that had increased to 9cm in size. Colonoscopy demonstrated a submucosal tumor, which was subsequently diagnosed by biopsy as a GIST. Due to the patient's continuous bleeding and abdominal pain, an emergent abdominoperineal resection was performed at that time. The tumor, which measured 8×9cm, was immunohistochemically positive for c-kit and CD34. Concomitant resection of the posterior wall of the vagina via the perineal approach provided a wide area to expose the tumor for a safe operation. The patient has been well with no sign of recurrence since the operation. This procedure is recommended as a useful approach for giant rectal GISTs or rectal cancer with invasion of the posterior pelvic wall. |
| キーワード | 巨大直腸GIST（giant rectal GIST） 腹会陰式直腸切断術（abdominoperineal resection） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-12-01 |
| 巻 | 126巻 |
| 号 | 3号 |
| 開始ページ | 217 |
| 終了ページ | 221 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.217 |
| NAID | 130004903245 |
| 著者 | Kono, Syoichiro| Deguchi, Kentaro| Omote, Yoshio| Yunoki, Taijun| Yamashita, Toru| Kurata, Tomoko| Ikeda, Yoshio| Abe, Koji| |
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| 発行日 | 2014-01 |
| 出版物タイトル | Journal of Neuroscience Research |
| 巻 | 92巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Omote, Yoshio| Deguchi, Kentaro| Tian, FengFeng| Kawai, Hiromi| Kurata, Tomoko| Yamashita, Toru| Ohta, Yasuyuki| Abe, Koji| |
|---|---|
| 発行日 | 2012-06 |
| 出版物タイトル | Stroke |
| 巻 | 43巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| タイトル（別表記） | A case of asymptomatic right-sided adult Bochdalek hernia presented incidentally with rectal tumor |
|---|---|
| フルテキストURL | 126_137.pdf |
| 著者 | 加藤 大| 大石 正博| 小寺 正人| 山村 方夫| 池田 秀明| 水野 憲治| 山下 裕| 鈴木 一則| |
| 抄録 | We encountered a patient with an adult Bochdalek hernia discovered asymptomatically. A 77-year-old Japanese woman visited a local clinic with chief complaints of melena and difficulty in defecation. Based on the results of the detailed examination in our hospital, she was diagnosed with a rectal gastrointestinal stromal tumor (GIST) with a concurrent asymptomatic adult right-sided Bochdalek hernia. Because the tumor was large, laparoscopic abdominoperineal rectal amputation was performed after systemic imatinib therapy. During the surgery, we found a right diaphragmatic defect more than 13cm in long dia., through which the right hepatic lobe, colon, and greater omentum had prolapsed into the right thoracic cavity. No visceral adhesions were noted. No hernia sac was observed. Adult Bochdalek hernia is a relatively rare condition, and only three (incidentally discovered) cases of asymptomatic Bochdalek hernia, including the present case, have been reported in Japan. Here we provide a case report for the patient, who was followed-up without hernia surgery, plus a review of the literature. |
| キーワード | 成人Bochdalek孔ヘルニア（adult Bochdalek hernia） 腹腔鏡下手術（laparoscopic surgery） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 137 |
| 終了ページ | 141 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.137 |
| NAID | 130004685265 |
| 著者 | 山下 広美| |
|---|---|
| 発行日 | 2014-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 30巻 |
| 資料タイプ | その他 |
| 著者 | 山下 浩一| |
|---|---|
| 発行日 | 1992-02 |
| 出版物タイトル | 日本産科婦人科学会中国四国合同地方部会雑誌 |
| 巻 | 40巻 |
| 号 | 2号 |
| 資料タイプ | 学術雑誌論文 |