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JaLCDOI 10.18926/AMO/67199
フルテキストURL 78_3_245.pdf
著者 Akagawa, Manabu| Saito, Hidetomo| Takahashi, Yasuhiro| Iwamoto, Yosuke| Iida, Junpei| Yoshikawa, Takayuki| Abe, Toshiki| Saito, Kimio| Kijima, Hiroaki| Kasukawa, Yuji| Hongo, Michio| Miyakoshi, Naohisa|
抄録 Although several studies have suggested a possible association between sarcopenia and knee osteoarthritis (OA) in the elderly, there remains no definitive evidence. Recently, however, the serum creatinine/cystatin C ratio (sarcopenia index: SI) was reported to correlate with skeletal muscle mass. The present retrospective study therefore investigated the impact of reduced skeletal muscle mass on advanced knee OA using SI. In 55 individuals scheduled for knee osteotomy or knee arthroplasty, correlations between SI and patient-reported outcomes such as the Knee Society Score (KSS), Knee Injury and Osteoarthritis Outcome Score (KOOS), and Oxford Knee Score (OKS) were explored. Significant associations were found between SI and the KSS functional activity score (β=0.37; p=0.022), KOOS subscale for activities of daily living (β=0.42; p=0.0096), and OKS (β=0.42; p=0.0095). This study underscores the role of reduced muscle mass in functional outcomes and introduces SI as a valuable marker for assessing muscle loss in knee OA patients.
キーワード knee osteoarthritis sarcopenia index reduced muscle mass activities of daily living functional activity
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2024-06
78巻
3号
出版者 Okayama University Medical School
開始ページ 245
終了ページ 250
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38902212
Web of Science KeyUT 001267351000005
JaLCDOI 10.18926/AMO/67198
フルテキストURL 78_3_237.pdf
著者 Muraoka, Osamu| Imai, Norio| Kuraishi, Tatsuya| Imai, Makoto| Fukuhara, Takashi| Yoshimine, Toshifumi|
抄録 Fracture liaison services (FLS) have been introduced in Japan and several other countries to reduce medical complications and secondary fractures. We aimed to evaluate the effects of the implementation of an FLS approach on patient outcomes during hospitalization at our hospital and over a 2-year follow-up post-injury. This retrospective cohort study included patients ≥ 60 years admitted to our hospital for hip fragility fractures between October 1, 2016, and July 31, 2020. Patient groups were defined as those treated before (control group, n=238) and after (FLS group, n=196) establishment of the FLS protocol at our institution. The two groups were compared in terms of time to surgery, length of hospital stay, and the incidence of complications after admission, including secondary hip fracture and mortality rates. The follow-up period was 24 months. FLS focuses on early surgery within 48 h of injury and assessing osteoporosis treatment before injury to guide post-discharge anti-osteoporosis medication. FLS reduced the length of hospital stay (p<0.001) and the prevalence of complications after admission (p<0.001), particularly cardiovascular disease, and it increased adherence to anti-osteoporosis medication. These FLS effects resulted in lower secondary hip fracture and mortality rates at 12 and 24 months post-injury. FLS for fragility hip fractures can improve patient outcomes during hospitalization and over a 2-year follow-up period.
キーワード fracture liaison services complications after admission secondary hip fracture mortality
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2024-06
78巻
3号
出版者 Okayama University Medical School
開始ページ 237
終了ページ 243
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38902211
Web of Science KeyUT 001267351000004
JaLCDOI 10.18926/AMO/67197
フルテキストURL 78_3_227.pdf
著者 Wada, Yudai| Ushio, Soichiro| Kitamura, Yoshihisa| Zamami, Yoshito| Sendo, Toshiaki|
抄録 Zolpidem, a non-benzodiazepine hypnotic, is primarily used to treat insomnia. In a previous study, pior treatment with non-benzodiazepine receptor agonists was associated with inflammation. The present study aimed to clarify the association between the effects of zolpidem and inflammation in mice treated with lipopolysaccharide (LPS), a known model of inflammation. We assessed the zolpidem-induced loss of righting reflex (LORR) duration 24 h after LPS treatment in mice. Additionally, the expressions of γ-aminobutyric acid (GABA)A receptor subunit and K+-Cl− cotransporter isoform 2 (KCC2) mRNA in the hippocampus and frontal cortex were examined in LPS-treated mice. Pretreatment with LPS was associated with significantly prolonged duration of zolpidem-induced LORR compared to control mice. This effect was significantly attenuated by administering bicuculline, a GABAA receptor antagonist, or flumazenil, a benzodiazepine receptor antagonist, in LPS-treated mice. Compared to controls, LPS-treated mice showed no significant change in the expression of GABAA receptor subunits in the hippocampus or frontal cortex. Bumetanide, an Na+-K+-2Cl− cotransporter isoform 1 blocker, attenuated the extended duration of zolpidem-induced LORR observed in LPS-treated mice. LPS significantly decreased Kcc2 mRNA expression in the hippocampus and the frontal cortex. These findings suggest that inflammation increases zolpidem-induced LORR, possibly through a reduction in KCC2 expression.
キーワード lipopolysaccharide zolpidem GABAA receptor K+-Cl− cotransporters
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2024-06
78巻
3号
出版者 Okayama University Medical School
開始ページ 227
終了ページ 235
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38902210
Web of Science KeyUT 001267351000003
JaLCDOI 10.18926/AMO/67196
フルテキストURL 78_3_215.pdf
著者 Akagawa, Takuya| Fukui, Ryohei| Kida, Katsuhiro| Matsuura, Ryutaro| Shimada, Makoto| Kinoshita, Mitsuhiro| Akagawa, Yoko| Goto, Sachiko|
抄録 We propose a sitting position that achieves both high image quality and a reduced radiation dose in elbow joint imaging by area detector computed tomography (ADCT), and we compared it with the ‘superman’ and supine positions. The volumetric CT dose index (CTDIvol) for the sitting, superman, and supine positions were 2.7, 8.0, and 20.0 mGy and the dose length products (DLPs) were 43.4, 204.7, and 584.8 mGy • cm, respectively. In the task-based transfer function (TTF), the highest value was obtained for the sitting position in both bone and soft tissue images. The noise power spectrum (NPS) of bone images showed that the superman position had the lowest value up to approx. 1.1 cycles/mm or lower, whereas the sitting position had the lowest value when the NPS was greater than approx. 1.1 cycles/mm. The overall image quality in an observer study resulted in the following median Likert scores for Readers 1 and 2: 5.0 and 5.0 for the sitting position, 4.0 and 3.5 for the superman position, and 4.0 and 2.0 for the supine position. These results indicate that our proposed sitting position with ADCT of the elbow joint can provide superior image quality and allow lower radiation doses compared to the superman and supine positions.
キーワード area detector computed tomography elbow joint sitting position dose reduction image quality assessment
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2024-06
78巻
3号
出版者 Okayama University Medical School
開始ページ 215
終了ページ 225
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38902209
Web of Science KeyUT 001267351000002
JaLCDOI 10.18926/AMO/67195
フルテキストURL 78_3_205.pdf
著者 Hagiya, Hideharu|
抄録 The global pandemic of COVID-19 has underscored the significance of establishing and sustaining a practical and efficient infection control system for the benefit and welfare of society. Infectious disease (ID) specialists are expected to take on leadership roles in enhancing organizational infrastructures for infection prevention and control (IPC) at the hospital, community, and national levels. However, due to an absolute shortage and an uneven distribution, many core hospitals currently lack the ID specialists. Given the escalating global risk of emerging and re-emerging infectious diseases as well as antimicrobial resistance pathogens, the education and training of ID specialists constitutes an imperative concern. As demonstrated by historical changes in the healthcare reimbursement system, the establishment and enhancement of IPC measures is pivotal to ensuring medical safety. The existing structure of academic society-driven certification and training initiatives for ID specialists, contingent upon the discretionary decisions of individual physicians, possesses both quantitative and qualitative shortcomings. In this article, I first address the present situations and challenges related to ID specialists and then introduce my idea of securing ID specialists based on the new concepts and platforms; (i) ID Specialists as National Credentials, (ii) Establishment of the Department of Infectious Diseases in Medical and Graduate Schools, (iii) Endowed ID Educative Courses Funded by Local Government and Pharmaceutical Companies, and (iv) Recruitment of Young Physicians Engaged in Healthcare Services in Remote Areas. As clarified by the COVID-19 pandemic, ID specialists play a crucial role in safeguarding public health. Hopefully, this article will advance the discussion and organizational reform for the education and training of ID specialists.
キーワード antimicrobial resistance emerging infectious diseases infection prevention and control medical education silent pandemic
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2024-06
78巻
3号
出版者 Okayama University Medical School
開始ページ 205
終了ページ 213
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38902208
Web of Science KeyUT 001267351000001
フルテキストURL fulltext.pdf
著者 Swe, Hnin‐Wint‐Wint| Fujisawa, Masayoshi| Ohara, Toshiaki| Komatsubara, Yu| Yoshimura, Teizo| Shien, Tadahiko| Matsukawa, Akihiro|
キーワード angiogenesis blood vessels breast cancer CD31 antigen immunohistochemistry microvessel density survival analysis
発行日 2024-05-31
出版物タイトル Pathology International
74巻
7号
出版者 Wiley
開始ページ 394
終了ページ 407
ISSN 1320-5463
NCID AA10984364
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 The Author(s).
論文のバージョン publisher
PubMed ID 38818885
DOI 10.1111/pin.13442
Web of Science KeyUT 001235649700001
関連URL isVersionOf https://doi.org/10.1111/pin.13442
フルテキストURL fulltext.pdf
著者 Ngo, An Thuy| Mori, Yasushi| Bui, Long Thanh|
キーワード Soil amendments water -saving polymers soil moisture improvement mean weight diameter irrigation water
発行日 2024-08
出版物タイトル Environmental Technology & Innovation
35巻
出版者 Elsevier
開始ページ 103650
ISSN 2352-1864
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 The Author(s).
論文のバージョン publisher
DOI 10.1016/j.eti.2024.103650
Web of Science KeyUT 001238871900001
関連URL isVersionOf https://doi.org/10.1016/j.eti.2024.103650
フルテキストURL fulltext.pdf
著者 Takamura, Hiroyoshi| Sugitani, Yuki| Morishita, Ryohei| Yorisue, Takefumi| Kadota, Isao|
発行日 2024
出版物タイトル Organic & Biomolecular Chemistry
22巻
28号
出版者 Royal Society of Chemistry (RSC)
開始ページ 5739
終了ページ 5747
ISSN 1477-0520
NCID AA1168650X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Royal Society of Chemistry 2024
論文のバージョン publisher
PubMed ID 38828517
DOI 10.1039/d4ob00698d
Web of Science KeyUT 001237473000001
関連URL isVersionOf https://doi.org/10.1039/d4ob00698d
フルテキストURL fulltext.pdf
著者 Ueno, Asami| Onishi, Yasuhiro| Mise, Koki| Yamaguchi, Satoshi| Kanno, Ayaka| Nojima, Ichiro| Higuchi, Chigusa| Uchida, Haruhito A.| Shikata, Kenichi| Miyamoto, Satoshi| Nakatsuka, Atsuko| Eguchi, Jun| Hida, Kazuyuki| Katayama, Akihiro| Watanabe, Mayu| Nakato, Tatsuaki| Tone, Atsuhito| Teshigawara, Sanae| Matsuoka, Takashi| Kamei, Shinji| Murakami, Kazutoshi| Shimizu, Ikki| Miyashita, Katsuhito| Ando, Shinichiro| Nunoue, Tomokazu| Wada, Jun|
発行日 2024-05
出版物タイトル BMJ Open Diabetes Research and Care
12巻
3号
出版者 BMJ Publishing Group
開始ページ e004237
ISSN 2052-4897
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Author(s) (or their employer(s)) 2024.
論文のバージョン publisher
PubMed ID 38816205
DOI 10.1136/bmjdrc-2024-004237
Web of Science KeyUT 001236385500001
関連URL isVersionOf https://doi.org/10.1136/bmjdrc-2024-004237
フルテキストURL fulltext.pdf
著者 Vo, Quan Duy| Saito, Yukihiro| Ida, Toshihiro| Nakamura, Kazufumi| Yuasa, Shinsuke|
発行日 2024-05-21
出版物タイトル PLoS ONE
19巻
5号
出版者 Public Library of Science
開始ページ e0302537
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 Vo et al.
論文のバージョン publisher
PubMed ID 38771829
DOI 10.1371/journal.pone.0302537
Web of Science KeyUT 001228816000059
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0302537
フルテキストURL fulltext.pdf
著者 Mao, Zhiyuan| Li, Xingyue| Li, Zhenhua| Shen, Liangliang| Li, Xiaoyi| Yang, Yanyan| Wang, Wenda| Kuang, Tingyun| Shen, Jian-Ren| Han, Guangye|
備考 The version of record of this article, first published in Nature Communications, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41467-024-48878-x|
発行日 2024-05-28
出版物タイトル Nature Communications
15巻
1号
出版者 Nature Portfolio
開始ページ 4535
ISSN 2041-1723
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2024
論文のバージョン publisher
PubMed ID 38806516
DOI 10.1038/s41467-024-48878-x
Web of Science KeyUT 001234660500031
関連URL isVersionOf https://doi.org/10.1038/s41467-024-48878-x
フルテキストURL fulltext.pdf
著者 Shibata, Masashi| Otsuka, Yuki| Hagiya, Hideharu| Koyama, Toshihiro| Kashiwagi, Hideyuki| Otsuka, Fumio|
発行日 2024-02-28
出版物タイトル PLoS ONE
19巻
2号
出版者 Public Library of Science
開始ページ e0299700
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 Shibata et al.
論文のバージョン publisher
PubMed ID 38416759
DOI 10.1371/journal.pone.0299700
Web of Science KeyUT 001181689500043
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0299700
フルテキストURL fulltext.pdf
著者 Zhang, Nan| An, Weichao| Yu, Yinghua| Wu, Jinglong| Yang, Jiajia|
キーワード response inhibition ratio go/no-go task ERP NoGo-P3 component
発行日 2024-04-24
出版物タイトル Brain Sciences
14巻
5号
出版者 MDPI
開始ページ 414
ISSN 2076-3425
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
PubMed ID 38790393
DOI 10.3390/brainsci14050414
Web of Science KeyUT 001232265800001
関連URL isVersionOf https://doi.org/10.3390/brainsci14050414
フルテキストURL fulltext.pdf
著者 Yamamoto, Koichiro| Oguni, Kohei| Otsuka, Fumio|
キーワード adrenal cyst adrenal incidentaloma adrenal tumor hypertension
発行日 2024-05-24
出版物タイトル Clinical Case Reports
12巻
6号
出版者 Wiley
開始ページ e8914
ISSN 2050-0904
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 The Author(s).
論文のバージョン publisher
PubMed ID 38799545
DOI 10.1002/ccr3.8914
Web of Science KeyUT 001230589300001
関連URL isVersionOf https://doi.org/10.1002/ccr3.8914
フルテキストURL fulltext.pdf
著者 Sakurada, Takato| Chikada, Yuta| Miyahara, Ryo| Taniguchi, Yosuke|
キーワード 8-oxo-2 '-deoxyguanosine single nucleotide elongation reaction artificial nucleoside triphosphate 2 '-deoxycytidine derivatives
発行日 2024-05-11
出版物タイトル Molecules
29巻
10号
出版者 MDPI
開始ページ 2270
ISSN 1420-3049
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
PubMed ID 38792131
DOI 10.3390/molecules29102270
Web of Science KeyUT 001231259100001
関連URL isVersionOf https://doi.org/10.3390/molecules29102270
フルテキストURL fulltext.pdf
著者 Sue, Masahiko| Takeuchi, Yasuto| Hirata, Shoichiro| Takaki, Akinobu| Otsuka, Motoyuki|
キーワード immune-related adverse events serum albumin real-world practice
発行日 2024-05-09
出版物タイトル Cancers
16巻
10号
出版者 MDPI
開始ページ 1811
ISSN 2072-6694
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
PubMed ID 38791890
DOI 10.3390/cancers16101811
Web of Science KeyUT 001233134000001
関連URL isVersionOf https://doi.org/10.3390/cancers16101811
フルテキストURL fulltext.pdf
著者 Mu, Xindi| Ono, Mitsuaki| Nguyen, Ha Thi Thu| Wang, Ziyi| Zhao, Kun| Komori, Taishi| Yonezawa, Tomoko| Kuboki, Takuo| Oohashi, Toshitaka|
キーワード cell differentiation epithelia growth factor(s) bioinformatics extracellular matrix (ECM) mucocutaneous disorders
発行日 2024-05-09
出版物タイトル Cells
13巻
10号
出版者 MDPI
開始ページ 807
ISSN 2073-4409
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
PubMed ID 38786031
DOI 10.3390/cells13100807
Web of Science KeyUT 001232270600001
関連URL isVersionOf https://doi.org/10.3390/cells13100807
フルテキストURL fulltext.pdf
著者 Moriwake, Kazuya| Noma, Kazuhiro| Kawasaki, Kento| Matsumoto, Tasuku| Hashimoto, Masashi| Kato, Takuya| Maeda, Naoaki| Tanabe, Shunsuke| Shirakawa, Yasuhiro| Fujiwara, Toshiyoshi|
キーワード Reconstruction with the free jejunum flap Subtotal esophagectomy After pancreatoduodenectomy
備考 The version of record of this article, first published in Surgical Case Reports, is available online at Publisher’s website: http://dx.doi.org/10.1186/s40792-024-01919-5|
発行日 2024-05-22
出版物タイトル Surgical Case Reports
10巻
1号
出版者 Springer
開始ページ 128
ISSN 2198-7793
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2024.
論文のバージョン publisher
PubMed ID 38775882
DOI 10.1186/s40792-024-01919-5
Web of Science KeyUT 001229350000001
関連URL isVersionOf https://doi.org/10.1186/s40792-024-01919-5
フルテキストURL fulltext.pdf
著者 Miyoshi, Shin-Ichi| Kurata, Megumi| Hirose, Riho| Yoshikawa, Masaya| Liang, Yong| Yamagishi, Yosuke| Mizuno, Tamaki|
キーワード Vibrio cholerae Vibrio vulnificus genotype LAMP water temperature
発行日 2024-04-27
出版物タイトル Microorganisms
12巻
5号
出版者 MDPI
開始ページ 877
ISSN 2076-2607
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
PubMed ID 38792707
DOI 10.3390/microorganisms12050877
Web of Science KeyUT 001231571500001
関連URL isVersionOf https://doi.org/10.3390/microorganisms12050877
フルテキストURL fulltext.pdf
著者 Maruyama, Takayuki| Ekuni, Daisuke| Yokoi, Aya| Nagasaki, Junichiro| Sawada, Nanami| Morita, Manabu|
キーワード halitosis antimicrobial photodynamic therapy prevention randomized clinical trial
発行日 2024-05-09
出版物タイトル Healthcare
12巻
10号
出版者 MDPI
開始ページ 980
ISSN 2227-9032
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
PubMed ID 38786391
DOI 10.3390/healthcare12100980
Web of Science KeyUT 001232995300001
関連URL isVersionOf https://doi.org/10.3390/healthcare12100980