検索結果 26357 件
| JaLCDOI | 10.18926/AMO/45269 |
|---|---|
| フルテキストURL | 65_2_105.pdf |
| 著者 | Tsuzuki, Takao| Okada, Hiroyuki| Nasu, Junichiro| Takenaka, Ryuta| Inoue, Masafumi| Kawano, Seiji| Kita, Masahide| Hori, Keisuke| Yamamoto, Kazuhide| |
| 抄録 | The objectives of this study were to evaluate the accuracy of endoscopic ultrasonography (EUS) in local and regional staging of early gastric cancer, to analyze the factors influencing the accuracy of EUS, and to reveal the usefulness and problems of EUS in pre-treatment staging of gastric cancer. We examined 105 lesions in 104 patients with histologically confirmed gastric cancer and retrospectively evaluated them with EUS. The diagnostic accuracy, sensitivity, and specificity of EUS were determined by comparing the pre-treatment EUS with the postoperative histopathological findings. The overall diagnostic accuracy of EUS for the depth of cancer invasion was 86%. The overall sensitivity and specificity were 60% and 96%, respectively. The accuracy significantly declined in lesions located in the upper-third of the stomach (70%). Type 0-I lesions tended to be over-staged (12&), and the upper-third lesions tended to be under-staged (23%). The accuracy significantly declined in differentiated adenocarcinoma with massive submucosal invasion (56.5%). EUS is useful for evaluating the depth of gastric cancer invasion which determines the feasibility of endoscopic treatment. However, it is noteworthy that the diagnostic accuracy of the invasion depth diminished for lesions in the upper third of the stomach. |
| キーワード | endoscopic ultrasonography early gastric cancer accuracy sensitivity specificity |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2011-04 |
| 巻 | 65巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 105 |
| 終了ページ | 112 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21519368 |
| Web of Science KeyUT | 000289818800006 |
| JaLCDOI | 10.18926/AMO/45268 |
|---|---|
| フルテキストURL | 65_2_97.pdf |
| 著者 | Tsuchihashi, Yuuki| Yorifuji, Takashi| Takao, Soshi| Suzuki, Etsuji| Mori, Shigeru| Doi, Hiroyuki| Tsuda, Toshihide| |
| 抄録 | Seasonal influenza infection is a major challenge in public health. The term "seasonal influenza" refers to the typical increase in the number of influenza patients in the winter season in temperature zones. However, it is not clear how environmental factors within a single flu season affect influenza infection in a human population. Therefore, we evaluated the effects of temperature and humidity in the 2006-7 flu season on the onset of seasonal influenza using a case-crossover study. We targeted patients who attended one pediatric clinic in Okayama city, Japan and who were diagnosed as being infected with the seasonal influenza virus. Using 2 references (time-stratified and symmetric bidirectional design), we estimated the effects of average temperature and relative humidity from the onset day (lag0) to 10 days before (lag10). The total number of subjects was 419, and their onset days ranged from 26 December 2006 to 30 April 2007. While the onset was significantly associated with lower temperature, relative humidity was not related. In particular, temperatures before the 3-day incubation period had higher-magnitude odds ratios. For example, the odds ratio and 95% confidence interval for average temperature at time lag 8 was 1.12 (1.08-1.17) per 1.0℃ decrease. Low environmental temperature significantly increased the risk of seasonal influenza onset within the 2006-7 winter season. |
| キーワード | seasonal influenza in humans temperature humidity case-crossover study |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2011-04 |
| 巻 | 65巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 97 |
| 終了ページ | 103 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21519367 |
| Web of Science KeyUT | 000289818800005 |
| JaLCDOI | 10.18926/AMO/45267 |
|---|---|
| フルテキストURL | 65_2_91.pdf |
| 著者 | Nagamatsu, Tomohiro| Sakoda, Akihiro| Kataoka, Takahiro| Ono, Toshiro| Yamaoka, Kiyonori| |
| 抄録 | No research has been conducted on the radiation influence of tobacco on the alimentary system, although there have been some previous works on the respiratory system. In this study, the radioactive concentrations of 210Pb and 40K in a cigarette sample were first measured. The transfer factors of the nuclides from tobacco into smoke and solution (saliva and/or alcohol) were then examined. Moreover, the radiation doses from smoke inhalation were also evaluated. The radioactive concentrations of 210Pb and 40K in the cigarette tobacco were 0.01 and 0.3 Bq/cigarette. Since this 210Pb activity and the 210Po activity previously reported for the same sample were comparable, it can be concluded that there was a radioactive equilibrium between the 2 nuclides. The observed transfer factor of 210Pb (12%) into smoke was almost the same as that of 40K (15%), whereas the reported value for 210Po (60%) was significantly higher. The radiation doses due to inhalation of cigarette smoke varied from organ to organ, depending on the organotropic properties of the nuclide. For example, the kidneys, respiratory tract, and spleen showed relatively high doses from 210Pb and 210Po. The leaching rates indicated an inconsistent tendency related to solution types. This result could suggest that alcohol drinking, which is common in smokers, does not especially enhance the leaching characteristics. |
| キーワード | tobacco radionuclides smoking intake radiation exposure |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2011-04 |
| 巻 | 65巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 91 |
| 終了ページ | 95 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21519366 |
| Web of Science KeyUT | 000289818800004 |
| JaLCDOI | 10.18926/AMO/45266 |
|---|---|
| フルテキストURL | 65_2_81.pdf |
| 著者 | Sasaki, Motofumi| Shikata, Kenichi| Okada, Shinichi| Miyamoto, Satoshi| Nishishita, Shingo| Usui Kataoka, Hitomi| Sato, Chikage| Wada, Jun| Ogawa, Daisuke| Makino, Hirofumi| |
| 抄録 | Glomerular hyperfiltration is a common pathway leading to glomerulosclerosis in various kinds of kidney diseases. The 5/6 renal ablation is an established experimental animal model for glomerular hyperfiltration. On the other hand, low-grade inflammation is also a common mechanism for the progression of kidney diseases including diabetic nephropathy and atherosclerosis. Here we analyzed the gene expression profile in the remnant kidney tissues of 5/6 nephrectomized mice using a DNA microarray system and compared it with that of sham-operated control mice. The 5/6 nephrectomized mice showed glomerular hypertrophy and an increase in the extracellular matrix in the glomeruli. DNA microarray analysis indicated the up-regulated expression of various kinds of genes related to the inflammatory process in remnant kidneys. We confirmed the up-regulated expression of platelet factor-4, and monocyte chemoattractant protein-1, 2, and 5 in remnant kidneys by RT-PCR. The current results suggest that the inflammatory process is involved in the progression of glomerulosclerosis and is a common pathway of the pathogenesis of kidney disease. |
| キーワード | kidney inflammation chemokine |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2011-04 |
| 巻 | 65巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 81 |
| 終了ページ | 89 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21519365 |
| Web of Science KeyUT | 000289818800003 |
| JaLCDOI | 10.18926/AMO/45265 |
|---|---|
| フルテキストURL | 65_2_71.pdf |
| 著者 | Sato, Kimiko| Oda, Megumi| |
| 抄録 | A questionnaire survey was administered to 317 parents who attended infant health check-ups in City B, Okayama Prefecture between October, 2008 and March, 2009. The questionnaire survey studied 7 factors based on the PRECEDE-PROCEED Model. We analysed factors that affected oral health behaviour and attendance at scheduled dental health check-ups. The survey containing 22 items concerning matters such as 'QOL' and 'health problems' was posted to parents and guardians in advance, and then collected on the day of the medical check-up. The collected data was analysed using the t-test and Pearson's correlation coefficient, following which we conducted a covariance structure analysis. The results showed that dental health behaviour was directly affected by reinforcing factors, and indirectly associated with enabling and predisposing factors influenced by reinforcing factors. It was also shown that predisposing factors and oral health behaviour were associated with attendance at scheduled oral health check-ups. The results indicated that strengthening oral health education by sharing knowledge that acts as predisposing factors and introducing adaptations of oral health behaviour that that fit individual lives will lead to improved attendance at scheduled dental health check-ups. |
| キーワード | PRECEDE-PROCEED model dental check-ups dental health behaviour |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2011-04 |
| 巻 | 65巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 71 |
| 終了ページ | 80 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21519364 |
| Web of Science KeyUT | 000289818800002 |
| JaLCDOI | 10.18926/AMO/45264 |
|---|---|
| フルテキストURL | 65_2_63.pdf |
| 著者 | Mizoguchi, Yoshinori| Suzuki, Etsuji| Tsuchida, Hiroaki| Tsuda, Toshihide| Yamamoto, Eiji| Nakase, Katsumi| Doi, Hiroyuki| |
| 抄録 | There have been only 2 reports of a large-scale foodborne outbreak arising from Salmonella enterica serotype Braenderup infection worldwide. On August 9, 2008, an outbreak originating in boxed lunches occurred in Okayama, Japan. We conducted a cohort study of 786 people who received boxed lunches from a particular catering company and collected 644 questionnaires (response rate:82%). Cases were defined as those presenting with diarrhea (≧4 times in 24h) or fever (≧38℃) between 12 am on August 8 and 12 am on August 14. We identified 176 cases (women/men:39/137);younger children (aged＜10 years) appeared to more frequently suffer severe symptoms. Three food items were significantly associated with higher risk of illness;tamagotoji (soft egg with mixed vegetables and meat) (relative risk (RR):11.74, 95% confidence interval (CI):2.98-46.24), pork cooked in soy sauce (RR:3.17, 95% CI:1.24-8.10), and vinegared food (RR:4.13, 95% CI:1.60-10.63). Among them, only the RR of tamagotoji was higher when we employed a stricter case definition. Salmonella Braenderup was isolated from 5 of 9 sampled cases and 6 food handlers. It is likely that unpasteurized liquid eggs contaminated by Salmonella Braenderup and used in tamagotoji caused this outbreak. |
| キーワード | boxed lunch cohort study foodborne diseases Salmonella Braenderup unpasteurized liquid eggs |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2011-04 |
| 巻 | 65巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 63 |
| 終了ページ | 69 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2011 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 21519363 |
| Web of Science KeyUT | 000289818800001 |
| 著者 | 岡山医学会| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | その他 |
| 著者 | 岡山医学会| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | その他 |
| 著者 | 水野 文次郎| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 小泉 道徳| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 檀上 順三| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 浮田 勝造| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 長谷川 恒治| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 安原 節太郎| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 平井出 正三| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 菊澤 隆尚| 瀧川 克巳| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 桃井 寛次| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 渡邊 眞澄| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 山本 春海| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 橘 捷夫| |
|---|---|
| 発行日 | 1935-06-30 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 47巻 |
| 号 | 6号 |
| 資料タイプ | 学術雑誌論文 |