検索結果 - 岡山大学学術成果リポジトリ

New mechanistic insight into SARM1 activation: TRIM32-mediated ubiquitination is a key lever that actuates SARM1’s catalytic action, leading to axon degeneration and cell death

フルテキストURL	fulltext.pdf
著者	Murata, Hitoshi\| Tomonobu, Nahoko\| Yamamoto, Ken-ichi\| Kinoshita, Rie\| Sakaguchi, Masakiyo\|
キーワード	axon degeneration NAD + SARM1 TRIM32 ubiquitination
発行日	2026-08-20
出版物タイトル	Frontiers in Neural Circuits
巻	20巻
出版者	Frontiers Media SA
開始ページ	1842408
ISSN	1662-5110
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2026 Murata, Tomonobu, Yamamoto, Kinoshita and Sakaguchi.
論文のバージョン	publisher
DOI	10.3389/fncir.2026.1842408
関連URL	isVersionOf https://doi.org/10.3389/fncir.2026.1842408

Efficacy of bepotastine compared with hydroxyzine in preventing rituximab-induced infusion-related reactions in non-hodgkin lymphoma patients: a phase II, double-blind, multicenter, and randomized trial

フルテキストURL	fulltext.pdf
著者	Kitahiro, Yumi\| Minami, Hironobu\| Yamamoto, Kazuhiro\| Yakushijin, Kimikazu\| Kurata, Keiji\| Sakai, Rina\| Saeki, Miki\| Okazoe-Hirakawa, Yuri\| Iida, Kotaro\| Murase, Natsuko\| Harima, Isamu\| Kitamura, Naoko\| Itohara, Kotaro\| Omura, Tomohiro\| Sugimoto, Takeshi\| Takakura, Hidetomo\| Kitao, Akihito\| Takahashi, Masako\| Shimoyama, Manabu\| Okuno, Mamoru\| Yano, Ikuko\|
キーワード	Rituximab Infusion-related reactions Non-Hodgkin lymphoma Bepotastine Hydroxyzine Drowsiness
発行日	2026-04-16
出版物タイトル	International Journal of Clinical Oncology
巻	31巻
号	6号
出版者	Springer Science and Business Media LLC
開始ページ	979
終了ページ	988
ISSN	1341-9625
NCID	AA11086579
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2026
論文のバージョン	publisher
PubMed ID	41989666
DOI	10.1007/s10147-026-03012-3
Web of Science KeyUT	001741935800001
関連URL	isVersionOf https://doi.org/10.1007/s10147-026-03012-3

Digital Tattoos in Infectious Diseases Management

フルテキストURL	fulltext.pdf
著者	Hagiya, Hideharu\|
キーワード	antibiotic allergy antimicrobial resistance infectious diseases isolation stigma
発行日	2026-06
出版物タイトル	Open Forum Infectious Diseases
巻	13巻
号	6号
出版者	Oxford University Press (OUP)
開始ページ	ofag338
ISSN	2328-8957
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2026.
論文のバージョン	publisher
PubMed ID	42292769
DOI	10.1093/ofid/ofag338
Web of Science KeyUT	001790643800001
関連URL	isVersionOf https://doi.org/10.1093/ofid/ofag338

Potential effects of intradialytic exercise therapy on physical performance in hemodialysis patients based on the intervention period: a systematic review and meta-analysis

フルテキストURL	fulltext.pdf
著者	Uchida, Daisuke\| Honda, Yu\| Kojima, Shigeki\| Miyake, Hiromasa\| Nishimoto, Masatoshi\| Hishikawa, Akihito\| Tonomura, Shun\| Sofue, Tadashi\| Fujii, Naohiko\| Saitoh, Masakazu\| Narita, Ichiei\| Yamagata, Kunihiro\| Hoshino, Junichi\| Kawarazaki, Hiroo\| Sakurada, Tsutomu\|
キーワード	Intradialytic exercise Physical performance Exercise period Short physical performance battery Handgrip strength Systematic review Meta-analysis
発行日	2026-04-03
出版物タイトル	Renal Replacement Therapy
巻	12巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	19
ISSN	2059-1381
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2026.
論文のバージョン	publisher
DOI	10.1186/s41100-026-00716-0
Web of Science KeyUT	001732879200001
関連URL	isVersionOf https://doi.org/10.1186/s41100-026-00716-0

Duration-stratified effects of exercise therapy on health-related quality of life in hemodialysis patients: a systematic review and meta-analysis

フルテキストURL	fulltext.pdf
著者	Honda, Yu\| Uchida, Daisuke\| Kojima, Shigeki\| Miyake, Hiromasa\| Nishimoto, Masatoshi\| Hishikawa, Akihito\| Tonomura, Shun\| Sofue, Tadashi\| Fujii, Naohiko\| Saitoh, Masakazu\| Narita, Ichiei\| Yamagata, Kunihiro\| Hoshino, Junichi\| Kawarazaki, Hiroo\| Sakurada, Tsutomu\|
キーワード	Hemodialysis Exercise therapy Intradialytic exercise Health-related quality of life Fatigue Depression Randomized controlled trials Meta-analysis
発行日	2026-03-08
出版物タイトル	Renal Replacement Therapy
巻	12巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	13
ISSN	2059-1381
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2026.
論文のバージョン	publisher
DOI	10.1186/s41100-026-00710-6
Web of Science KeyUT	001711622100001
関連URL	isVersionOf https://doi.org/10.1186/s41100-026-00710-6

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

フルテキストURL	fulltext.pdf
著者	Nakamura, Misaki\| Tanaka, Hiroyoshi Y.\| Ohira, Mayu\| Ohta‐Okano, Haruko\| Nakamura, Reika\| Seno, Yu\| Yara, Saaya\| Fujita, Sakura\| Shibata, Daichi\| Yamamoto, Masaya\| Toyooka, Shinichi\| Osada, Kensuke\| Cabral, Horacio\| Masamune, Atsushi\| Kano, Mitsunobu R.\|
キーワード	fibrosis nanomedicine NUAK kinase pancreatic cancer tumor microenvironment
発行日	2026-02-24
出版物タイトル	Advanced NanoBiomed Research
巻	6巻
号	6号
出版者	Wiley
開始ページ	e202500237
ISSN	2699-9307
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2026 The Author(s).
論文のバージョン	publisher
DOI	10.1002/anbr.202500237
関連URL	isVersionOf https://doi.org/10.1002/anbr.202500237

Knockout analysis of period and timeless and EGFP-based visualization of per-expressing clock cells in the cricket circadian clock

フルテキストURL	fulltext.pdf
著者	Tomioka, Kenji\| Inoue, Shintaro\| Mito, Taro\| Moriyama, Yoshiyuki\| Yoshii, Taishi\|
キーワード	Circadian clock Cricket Genome editing Locomotor rhythm period per-less oscillation timeless
発行日	2026-07-07
出版物タイトル	Zoological Letters
巻	12巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	12
ISSN	2056-306X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2026.
論文のバージョン	publisher
PubMed ID	42415196
DOI	10.1186/s40851-026-00267-6
Web of Science KeyUT	001818369400001
関連URL	isVersionOf https://doi.org/10.1186/s40851-026-00267-6

ベイズ推定を用いたラジオクロミックフィルムのADC値–線量変換法

タイトル（別表記）	A Bayesian Approach to ADC-to-Dose Conversion in Radiochromic Film Dosimetry
フルテキストURL	fulltext.pdf
著者	谷本祐樹\| 杉本昂平\| 田盛雅英\| 八木美保\| 吉田昌平\| 菅原一真\| 笈田将皇\|
キーワード	radiation therapy quality assurance patient-specific IMRT QA radiochromic film Bayesian inference
発行日	2026
出版物タイトル	日本放射線技術学会雑誌
巻	82巻
号	10号
出版者	公益社団法人日本放射線技術学会
開始ページ	26-1707
ISSN	0369-4305
NCID	AN00197784
資料タイプ	学術雑誌論文
言語	日本語
OAI-PMH Set	岡山大学
著作権者	© 2026 公益社団法人日本放射線技術学会
論文のバージョン	publisher
PubMed ID	42618285
DOI	10.6009/jjrt.26-1707
CRID	1390309293225291520
関連URL	isVersionOf https://doi.org/10.6009/jjrt.26-1707

Structural insights into tRNA recognition of the human FTSJ1-THADA complex

フルテキストURL	fulltext.pdf
著者	Ishiguro, Kensuke\| Fujimura, Atsushi\| Shirouzu, Mikako\|
発行日	2025-06-07
出版物タイトル	Communications Biology
巻	8巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	893
ISSN	2399-3642
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	40483304
DOI	10.1038/s42003-025-08278-3
Web of Science KeyUT	001504321200002
関連URL	isVersionOf https://doi.org/10.1038/s42003-025-08278-3

Trastuzumab-Pertuzumab Plus Eribulin or Taxane as First-Line Chemotherapy for Human Epidermal Growth Factor 2–Positive Locally Advanced/Metastatic Breast Cancer: The Randomized Noninferiority Phase III EMERALD Trial

フルテキストURL	fulltext.pdf
著者	Yamashita, Toshinari\| Saji, Shigehira\| Takano, Toshimi\| Naito, Yoichi\| Tsuneizumi, Michiko\| Yoshimura, Akiyo\| Takahashi, Masato\| Tsurutani, Junji\| Iwatani, Tsuguo\| Kitada, Masahiro\| Tada, Hiroshi\| Mori, Natsuko\| Higuchi, Toru\| Iwasa, Tsutomu\| Araki, Kazuhiro\| Koizumi, Kei\| Hasegawa, Hiroki\| Uchida, Yohei\| Morita, Satoshi\| Masuda, Norikazu\|
発行日	2025-04-10
出版物タイトル	Journal of Clinical Oncology
巻	43巻
号	11号
出版者	American Society of Clinical Oncology (ASCO)
開始ページ	1302
終了ページ	1313
ISSN	0732-183X
NCID	AA10638385
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by American Society of Clinical Oncology
論文のバージョン	publisher
PubMed ID	39787453
DOI	10.1200/jco-24-01888
Web of Science KeyUT	001459338900001
関連URL	isVersionOf https://doi.org/10.1200/jco-24-01888

Hormonal changes revealed by selective arterial calcium injection tests in patients with insulinoma treated with EUS–guided ethanol injection

フルテキストURL	fulltext.pdf
著者	Matsumoto, Kazuyuki\| Komatsubara, Motoshi\| Inagaki, Kenichi\| Kato, Hironari\| Otuka, Motoyuki\|
発行日	2024-05
出版物タイトル	Endoscopic Ultrasound
巻	13巻
号	3号
出版者	Ovid Technologies (Wolters Kluwer Health)
開始ページ	193
終了ページ	195
ISSN	2226-7190
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 The Author(s).
論文のバージョン	publisher
PubMed ID	39318649
DOI	10.1097/eus.0000000000000058
Web of Science KeyUT	001281650400006
関連URL	isVersionOf https://doi.org/10.1097/eus.0000000000000058

Performance of generative artificial intelligence in oral and maxillofacial radiology based on the board-certification examination of Japan

フルテキストURL	fulltext.pdf
著者	Takeshita, Yohei\| Kawazu, Toshiyuki\| Hisatomi, Miki\| Fujikura, Mamiko\| Okada, Shunsuke\| Shibanuma, Akira\| Namba, Yuri\| Yoshida, Suzuka\| Yoshida, Saori\| Nakamura, Yoshihide\| Yanagi, Yoshinobu\|
キーワード	Artificial intelligence Generative artificial intelligence ChatGPT Large language model Radiology Education
発行日	2026-08-20
出版物タイトル	Oral Radiology
出版者	Springer Science and Business Media LLC
ISSN	0911-6028
NCID	AA10689728
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2026
論文のバージョン	publisher
PubMed ID	42622945
DOI	10.1007/s11282-026-00965-z
関連URL	isVersionOf https://doi.org/10.1007/s11282-026-00965-z

Efficacy and Safety of Three Janus Kinase Inhibitors in Ulcerative Colitis Patients over and under 65 Years of Age: A Real-World Comparative Analysis

フルテキストURL	fulltext.pdf
著者	Akiyama, Shintaro\| Shimizu, Hiromichi\| Tamura, Akiko\| Yokoyama, Kaoru\| Sakurai, Toshiyuki\| Kobayashi, Mariko\| Eizuka, Makoto\| Yanai, Shunichi\| Nomura, Kei\| Shibuya, Tomoyoshi\| Takahara, Masahiro\| Hiraoka, Sakiko\| Sako, Minako\| Yoshida, Atsushi\| Tsuruta, Kozo\| Yoshioka, Shinichiro\| Koroku, Miki\| Omori, Teppei\| Saruta, Masayuki\| Matsumoto, Takayuki\| Okamoto, Ryuichi\| Tsuchiya, Kiichiro\| Fujii, Toshimitsu\|
キーワード	Elderly Janus kinase inhibitors Ulcerative colitis
発行日	2025-06-24
出版物タイトル	Inflammatory Intestinal Diseases
巻	10巻
号	1号
出版者	S. Karger AG
開始ページ	180
終了ページ	186
ISSN	2296-9403
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
PubMed ID	40667521
DOI	10.1159/000546640
関連URL	isVersionOf https://doi.org/10.1159/000546640

Inhibition of Scarb1 on Endothelial Cells Attenuates Pressure Overload-Induced Heart Failure Progression

フルテキストURL	fulltext.pdf
著者	Katsuki, Toshiomi\| Kusumoto, Dai\| Akiba, Yohei\| Kimura, Mai\| Komuro, Jin\| Nakamura, Takahiro\| Hashimoto, Hisayuki\| Kouka, Thukaa\| Sugai, Kazuhisa\| Katsumata, Yoshinori\| Miyasaka, Masaki\| Suzuki, Yutaka\| Kuramoto, Junko\| Kubota, Yoshiaki\| Fukuda, Keiichi\| Yuasa, Shinsuke\| Ieda, Masaki\|
キーワード	endothelial cells fibroblasts heart failure SCARB1
発行日	2025-10
出版物タイトル	JACC: Basic to Translational Science
巻	10巻
号	10号
出版者	Elsevier BV
開始ページ	101308
ISSN	2452-302X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Authors.
論文のバージョン	publisher
PubMed ID	40772900
DOI	10.1016/j.jacbts.2025.05.003
Web of Science KeyUT	001612354900003
関連URL	isVersionOf https://doi.org/10.1016/j.jacbts.2025.05.003

Vaccination in paediatric, adolescent, and transitional-age rheumatic diseases: a systematic review

フルテキストURL	fulltext.pdf
著者	Ohnishi, Takuma\| Wakiguchi, Hiroyuki\| Ishimori, Shingo\| Itoh, Naohiro\| Yashiro, Masato\| Yamazaki, Susumu\| Okafuji, Ikuo\| Ohtomo, Yoshiyuki\| Kobayashi, Ichiro\|
キーワード	Bacille Calmette–Guérin diphtheria, pertussis, and tetanus vaccine hepatitis A virus vaccine hepatitis B virus vaccine human papillomavirus vaccine inactivated polio vaccine influenza vaccine measles, mumps, and rubella vaccine pneumococcal vaccine varicella zoster virus vaccine
発行日	2025-07-25
出版物タイトル	Modern Rheumatology
巻	36巻
号	1号
出版者	Oxford University Press (OUP)
開始ページ	97
終了ページ	112
ISSN	1439-7595
NCID	AA1157187X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Japan College Rheumatology 2025.
論文のバージョン	publisher
PubMed ID	40709824
DOI	10.1093/mr/roaf069
Web of Science KeyUT	001551830200001
関連URL	isVersionOf https://doi.org/10.1093/mr/roaf069

Transcanal Cochlear Implantation Under Endoscopic Guidance with Canal Closure in a Pediatric Patient with CHARGE Syndrome: A Case Report and Surgical Technique

JaLCDOI	10.18926/AMO/71071
フルテキストURL	80_4_265.pdf
著者	Yamasaki, Takuto\| Sugaya, Akiko\| Naoi, Yuto\| Kariya, Shin\| Ando, Mizuo\|
抄録	Cochlear implantation (CI) in patients with CHARGE syndrome presents unique surgical challenges due to complex external, middle, and inner ear malformations. We describe the case of a 3-year-old Japanese boy for whom simultaneous transcanal CI under endoscopic guidance and external auditory canal closure were performed. This approach enabled safe electrode placement and resulted in favorable auditory outcomes, representing a potential novel surgical option for CI in patients with CHARGE syndrome. There are few reports of this type of surgical intervention, and the present case highlights the feasibility and clinical benefits of individualized surgical planning for CI in anatomically complex patients.
キーワード	CHARGE syndrome cochlear implantation transcanal approach temporal bone anomaly pediatric otologic surgery
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2026-08
巻	80巻
号	4号
出版者	Okayama University Medical School
開始ページ	265
終了ページ	270
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2026 by Okayama University Medical School
論文のバージョン	publisher
査読	有り

Spinous Process Plate Fixation Alone for an AO Spine Osteoporotic Fracture (OF) 5 Diffuse Idiopathic Skeletal Hyperostosis (DISH)-Associated Thoracolumbar Fracture in a Nonagenarian

JaLCDOI	10.18926/AMO/71070
フルテキストURL	80_4_259.pdf
著者	Yabuno, Satoru\| Yunoki, Masatoshi\| Takeuchi, Saori\| Hirashita, Koji\|
抄録	Diffuse idiopathic skeletal hyperostosis (DISH) predisposes the spine to highly unstable fractures because of long lever-arm biomechanics. Unstable injuries, including AO Spine Osteoporotic Fracture (OF) type 5, are typically treated with long-segment posterior instrumentation; however, pedicle-screw fixation may be infeasible in very elderly patients with severe osteoporosis, critically narrow pedicles, and/or significant comorbidities. A 93-year-old Japanese woman presented with severe back pain without apparent trauma. Computed tomography (CT) revealed a T12 fracture with DISH, classified as OF5. The pedicles were critically narrow (3.7-4.1 mm), and dual-energy X-ray absorptiometry confirmed severe osteoporosis. Because conventional pedicle-screw fixation was considered technically unsafe and excessively invasive, limited posterior stabilization was performed using a single spinous process plate spanning T10-L1. The operative time was 48 min and the estimated blood loss was 10 ml. Immediate postoperative CT confirmed appropriate implant positioning and maintained alignment. At the 1-year follow-up, CT demonstrated solid bony union with preserved alignment and no implant failure; the patient had remained pain-free and ambulatory. This case demonstrates that spinous process-plate fixation can be a minimally invasive salvage option for carefully selected very-elderly patients with DISH when pedicle-screw instrumentation is not feasible.
キーワード	DISH vertebral fracture osteoporosis spinous process plate
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2026-08
巻	80巻
号	4号
出版者	Okayama University Medical School
開始ページ	259
終了ページ	264
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2026 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
レファレンス	Resnick D and Niwayama G: Radiographic and pathologic features of spinal involvement in diffuse idiopathic skeletal hyperostosis (DISH). Radiology (1976) 119: 559-568.\| Wu Y, Ye Q, He D, Wei Y, Pan Y and Wang Y: Effect of Diffuse Idiopathic Skeletal Hyperostosis on the Occurrence of Thoracolumbar Vertebral Fragility Fractures at Different Ages. Global Spine J (2025) 15: 2075-2086.\| Harlianto NI, Ezzafzafi S, Foppen W, Kuperus JS, van der Horst-Bruinsma IE, de Jong PA and Verlaan JJ: The prevalence of vertebral fractures in diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis: A systematic review and meta-analysis. N Am Spine Soc J (2024) 17: 100312.\| Blattert TR, Schnake KJ, Gonschorek O, Gercek E, Hartmann F, Katscher S, Mork S, Morrison R, Muller M, Partenheimer A, Piltz S, Scherer MA, Ullrich BW, Verheyden A, Zimmermann V and the Spine Section of the German Society for Orthopaedics and Trauma. Nonsurgical and Surgical Management of Osteoporotic Vertebral Body Fractures: Recommendations of the Spine Section of the German Society for Orthopaedics and Trauma (DGOU). Global Spine J (2018) 8: 50-55.\| Tomii M, Itoh Y, Numazawa S, Watanabe K and Nakagawa H: Spinous process plate (S-plate) fixation after posterior interbody fusion for lumbar canal stenosis due to spondylolisthesis. Neurosurg Rev (2013) 36: 139-143.\| Diederichs G, Engelken F, Marshall LM, Peters K, Black DM, Issever AS, Barrett-Connor E, Orwoll E, Hamm B, Link TM and Osteoporotic Fractures in Men (MrOs) Research Group: Diffuse idiopathic skeletal hyperostosis (DISH): relation to vertebral fractures and bone density. Osteoporos Int (2011) 22: 1789-1797.\| Page PS, Greeneway GP, Lake WB, Brooks NP, Josiah DT, Hanna AS and Resnick DK: Outcomes following conservative treatment of extension fractures in the setting of diffuse idiopathic skeletal hyperostosis: is external orthosis alone a reasonable option? J Neurosurg Spine (2022) 37: 927-931.\| Solitro GF, Whitlock K, Amirouche F, Mehta AI and McDonnell A: Currently Adopted Criteria for Pedicle Screw Diameter Selection. Int J Spine Surg (2019) 13: 132-145.\| Matsukawa K, Yato Y, Hynes RA, Imabayashi H, Hosogane N, Asazuma T, Matsui T, Kobayashi Y and Nemoto K: Cortical Bone Trajectory for Thoracic Pedicle Screws: A Technical Note. Clin Spine Surg (2017) 30: 497-504.\| Wang H, Wang H, Sribastrav SS, Ye F, Liang C, Li Z, Wang J, Liu H, Wang X and Zheng Z: Comparison of pullout strength of the thoracic pedicle screw between intrapedicular and extrapedicular technique: a meta-analysis and literature review. Int J Clin Exp Med (2015) 8: 22237-22245.\| Ikuma H, Takao S, Inoue Y, Hirose T, Matsukawa K and Kawasaki K: Treatment of Thoracolumbar Spinal Fracture Accompanied by Diffuse Idiopathic Skeletal Hyperostosis Using Transdiscal Screws for Diffuse Idiopathic Skeletal Hyperostosis: Preliminary Results. Asian Spine J (2021) 15: 340-348.\| Hishiya T, Ishikawa T and Ota M: Posterior spinal fixation using penetrating endplate screws in patients with diffuse idiopathic skeletal hyperostosis-related thoracolumbar fractures. J Neurosurg Spine (2021) 34: 936-941.\| Nakao Y SS, Kimura M, Yamada T, Yamamoto Y and Takashiba K: Spinal fusion using a spinous process plate (S-plate)- clinical results and mechanical strength. The journal of the Japan Spine Research Society (2006) 17: 119.\| Ugawa R, Fujiwara Y and Matsumoto T: Clinical Outcomes of Transdiscal Screws for Thoracolumbar Spinal Fractures with Marked Anterior Distraction Gap Accompanied by Diffuse Idiopathic Skeletal Hyperostosis. Medicina (Kaunas) (2025) 61: 1-9.\|

Hemorrhage from a Jejunal Lymphangioma

JaLCDOI	10.18926/AMO/71069
フルテキストURL	80_4_253.pdf
著者	Ishikami, Sachiko\| Tamura, Shuta\| Tabuchi, Motoyasu\| Yamamoto, Nao\| Okamoto, Yuki\| Yoshimatsu, Rika\| Matsumoto, Manabu\| Iwata, Jun\| Okabayashi, Takehiro\|
抄録	Lymphangioma is a benign tumor arising from lymphatic vessel proliferation and most commonly occurs in the head, neck, or axilla. Involvement of the small intestine is rare and is often overlooked as a source of obscure gastrointestinal bleeding. Because jejunal lymphangiomas frequently present with nonspecific symptoms and may escape detection by conventional upper and lower gastrointestinal endoscopy or cross-sectional imaging, diagnosis is often delayed. Advances in balloon-assisted enteroscopy have enabled direct visualization of small intestinal lesions, facilitating accurate diagnosis and appropriate therapeutic decision-making. Here, we report a case of jejunal lymphangioma presenting with severe anemia due to active bleeding, which was detected by double-balloon endoscopy and successfully managed by laparoscopic-assisted resection. This case highlights the importance of considering small intestinal lymphangioma in the differential diagnosis of unexplained gastrointestinal bleeding and underscores the clinical utility of deep enteroscopy in identifying rare but clinically significant small bowel tumors.
キーワード	jejunal lymphangioma double-balloon endoscopy surgery
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2026-08
巻	80巻
号	4号
出版者	Okayama University Medical School
開始ページ	253
終了ページ	257
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2026 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
レファレンス	Galifer RB, Pous JG, Juskiewenski S, Pasquie M and Gaubert J: Intra-abdominal cystic lymphangiomas in childhood. Prog Pediatr Surg (1978) 11: 173-238.\| Chin CC, Shiau J, Luo CW and Hou MF: Lymphangioma of the small bowel in adults: a rare cause of abdominal symptoms. Asian J Surg (2023) 46: 863-867.\| Kida A, Matsuda K, Hirai S, Shimatani A, Horita Y, Hiramatsu K, Matsuda M, Ogino H, Ishizawa S and Noda Y: A pedunculated polyp-shaped small-bowel lymphangioma causing gastrointestinal bleeding and treated by double-balloon enteroscopy. World J Gastroenterol (2012) 18: 4798-4800.\| Zhao N, Fu Y, Wang Z, An Q and Jia W: Submucosal cavernous lymphangioma causing jejuno-jejunal intussusception in an adult: a case report. Front Surg (2022) 9: 953840.\| Hanagiri T, Baba M, Shimabukuro T, Hashimoto M, Takemoto H, Inoue A, Sugitani A and Shirakusa T: Lymphangioma in the small intestine: report of a case and review of the Japanese literature. Surg Today (1992) 22: 363-367.\| Cheung DY and Choi MG: Current advances in small bowel tumors. Clin Endosc (2011) 44: 13-21.\| Yamamoto H, Sekine Y, Sato Y, Higashizawa T, Miyata T, Iino S, Ido K and Sugano K: Total enteroscopy with a nonsurgical steerable double-balloon method. Gastrointest Endosc (2001) 53: 216-220.\| Pennazio M, Spada C, Eliakim R, Keuchel M, May A, Mulder CJ, Rondonotti E, Adler SN, Albert J, Baltes P, Barbaro F, Cellier C, Charton JP, Delvaux M, Despott EJ, Domagk D, Klein A, McAlindon M, Rosa B, Rowse G, Sanders DS, Saurin JC, Sidhu R, Dumonceau JM, Hassan C and Gralnek IM: Small-bowel capsule endoscopy and device-assisted enteroscopy. Endoscopy (2015) 47: 352-376.\| Peters FT, Rutgers EJ and Driessen WM: Intra-abdominal lymphangiomatous cysts in adults. Neth J Med (1987) 31: 152-157.\| Wang ZZ, Shen LY, Zhou JJ, Tang JL, Ye LP, Shen CB, Li SW and Zhou XB: Clinical manifestation and treatment of small intestinal lymphangioma: a single-center analysis of 15 cases. Front Med (Lausanne) (2022) 9: 975698.\| Iwabuchi A, Otaka M, Okuyama A, Jin M, Otani S, Itoh S, Sasahara H, Odashima M, Kotanagi H, Satoh M, Masuda H and Masamune O: Disseminated intra-abdominal cystic lymphangiomatosis with severe intestinal bleeding: a case report. J Clin Gastroenterol (1997) 25: 383-386.\| Tan B, Zhang SY, Wang YN, Li Y, Shi XH and Qian JM: Jejunal cavernous lymphangioma manifested as gastrointestinal bleeding with hypogammaglobulinemia in an adult: a case report and literature review. World J Clin Cases (2020) 8: 140-148.\| Meşină C, Paşalega M, Calotă F, Comănescu V, Vîlcea D, Tenea T, Mirea C and Vasile I: Hemorrhagic intestinal lymphangioma: report of a case. Chirurgia (Bucur) (2006) 101: 201-204.\| Lim DR, Kuk JC, Kim T and Shin EJ: Surgery of multiple lymphangioma in the small bowel: a rare case report of chronic gastrointestinal bleeding. Ann Surg Treat Res (2018) 94: 52-56.\| Barquist ES, Apple SK, Jensen DM and Ashley SW: Jejunal lymphangioma: an unusual cause of chronic gastrointestinal bleeding. Dig Dis Sci (1997) 42: 1179-1183.\| Xiao NJ, Ning SB, Li T, Li BR and Sun T: Small intestinal hemolymphangioma treated with enteroscopic injection sclerotherapy: a case report and review of the literature. World J Gastroenterol (2020) 26: 1540-1545.\| Yang J, Zhang Y, Kou G and Li Y: Jejunum hemolymphangioma causing refractory anemia in a young woman. Am J Gastroenterol (2020) 115: 810.\| Yang SX, Zhou YH, Zhang J, Miao L, Zhong JW, Wang WX, Xu CL, Cai ZZ and Lu GR: Haemorrhagic ileal haemolymphangioma: a case report and review of the literature. J Int Med Res (2021) 49: 300060520986677.\| Tomizawa Y, Garner K and Sohnen A: Lymphangioma of the small bowel mesentery: a rare intra-abdominal tumor causing anemia. Clin Gastroenterol Hepatol (2013) 11: e57.\| Fang YF, Qiu LF, Du Y, Jiang ZN and Gao M: Small intestinal hemolymphangioma with bleeding: a case report. World J Gastroenterol (2012) 18: 2145-2146.\| Park JG, Aubry MC, Godfrey JA and Midthun DE: Mediastinal lymphangioma: Mayo Clinic experience of 25 cases. Mayo Clin Proc (2006) 81: 1197-1203.\| Landing BH and Farber S: Tumors of the cardiovascular system. Atlas of tumor pathology Armed forces Inst. Path. Washington D. C 1956.\|

Post-Tracheostomy Fistula Formation Between the Trachea and Left Common Carotid Artery in a Pediatric Patient with Trisomy 18

JaLCDOI	10.18926/AMO/71068
フルテキストURL	80_4_247.pdf
著者	Shiina, Tsuyoshi\| Watanabe, Hirokazu\| Yoshimoto, Junko\| Sato, Takeshi\| Morimoto, Daisaku\| Okamura, Tomoka\| Tanimoto, Terutaka\| Washio, Yosuke\| Oyama, Takanori\| Tsukahara, Hirokazu\| Noda, Takuo\|
抄録	The long-term survival of individuals with trisomy 18 has improved, and the need for tracheostomy in this population has thus increased. We describe the case of a 3-year-old Japanese boy with trisomy 18 who developed a tracheoarterial fistula involving the left common carotid artery (LCCA). He underwent an emergency tracheostomy for respiratory failure secondary to pneumonia. Massive hemorrhage from the tracheostoma occurred on postoperative day 31, leading to his death. The autopsy revealed that the LCCA originated from the brachiocephalic trunk and coursed medially, forming a fistulous connection with the trachea. This case highlights the clinical importance of preoperative vascular mapping in patients with chromosomal abnormalities.
キーワード	tracheoarterial fistula tracheocarotid fistula trisomy 18
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2026-08
巻	80巻
号	4号
出版者	Okayama University Medical School
開始ページ	247
終了ページ	252
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2026 by Okayama University Medical School
論文のバージョン	publisher
査読	有り

Video-Assisted Thoracoscopic Resection of an Upper Mediastinal Ectopic Parathyroid Adenoma

JaLCDOI	10.18926/AMO/71067
フルテキストURL	80_4_241.pdf
著者	Hasegawa, Yuta\| Tsujimoto, Hironori\| Uehata, Naoyuki\| Kariya, Risa\| Ide, Asuma\| Suzuki, Takafumi\| Fujishima, Seiichiro\| Kouzu, Keita\| Yaguchi, Yoshihisa\| Miyai, Kosuke\| Kurihara, Ayumu\| Ogata, Sho\| Matsukuma, Susumu\| Ueno, Hideki\|
抄録	Primary hyperparathyroidism (pHPT) is typically caused by a parathyroid adenoma, although some cases arise from ectopic glands. Accurate preoperative localization is essential for guiding surgical strategy, particularly for mediastinal lesions. We report successful video-assisted thoracoscopic surgery (VATS) for an upper mediastinal parathyroid adenoma. A 68-year-old woman was referred for hypercalcemia during evaluation for recurrent ureteral stones. Laboratory tests revealed elevated serum calcium (13.2 mg/dl) and intact parathyroid hormone (iPTH) levels (266 pg/ml). Contrast-enhanced computed tomography, magnetic resonance imaging, and 99mTc-methoxyisobutylisonitrile scintigraphy identified a 20-mm mass adjacent to the right esophageal wall. VATS was performed due to the tumor’s mediastinal location. The lesion was resected with intraoperative nerve monitoring (IONM) to avoid recurrent laryngeal nerve damage. Postoperatively, iPTH and calcium levels rapidly normalized. Transient hypocalcemia and mild hoarseness occurred but resolved with calcium supplementation and conservative management. Pathological examination confirmed a parathyroid adenoma without malignancy. VATS offers a safe and minimally invasive approach for upper mediastinal parathyroid adenomas. IONM and vigilant calcium management are crucial for minimizing these complications. This case highlights the importance of comprehensive imaging, surgical planning, and postoperative care in managing upper mediastinal pHPT.
キーワード	primary hyperparathyroidism parathyroid neoplasm ectopic tissue video-assisted thoracoscopic surgery
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2026-08
巻	80巻
号	4号
出版者	Okayama University Medical School
開始ページ	241
終了ページ	246
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2026 by Okayama University Medical School
論文のバージョン	publisher
査読	有り