| ID | 17484 |
| Eprint ID | 17484
|
| フルテキストURL | |
| タイトル（別表記） | Experimental model of hyperargininemia Ⅱ. Identification of guanidinosuccinic acid in urine of the arginine loaded rabbit and a possible pathway of its formation
|
| 著者 |
洲脇 貞吉
岡山大学医学部脳代謝研究施設機能生化学部門
|
| 抄録 | Authentic guanidinosuccinic acid was converted into dimethylpyrimidyl derivative by reaction with acetylacetone, the carboxyl group was esterified by butylalcohol, and this derivative was analysed by the GC/MS technique. Then guanidinosuccinic acid was identified in urine of arginine loaded rabbit by means of selected ion recording. On the other hand, aspartic acid and isomolar of arginine was loaded simultaneously to rabbit, and a higher level of guanidinosuccinic acid was detected in the urine of 2 or 3 days and one week after. This fact suggest that guanidinosuccinic acid could be produced by transamidination of aspartic acid, receiving amidine group of arginine.
|
| 発行日 | 1978-12-30
|
| 出版物タイトル |
岡山医学会雑誌
|
| 出版物タイトル（別表記） | Journal of Okayama Medical Association
|
| 巻 | 90巻
|
| 号 | 11-12号
|
| 出版者 | 岡山医学会
|
| 出版者（別表記） | Okayama Medical Association
|
| 開始ページ | 1393
|
| 終了ページ | 1398
|
| ISSN | 0030-1558
|
| NCID | AN00032489
|
| 資料タイプ |
学術雑誌論文
|
| オフィシャル URL | https://www.jstage.jst.go.jp/article/joma1947/90/11-12/90_11-12_1393/_article/-char/ja/
|
| 関連URL | http://www.okayama-u.ac.jp/user/oma/index.html
|
| 言語 |
日本語
|
| 著作権者 | 岡山医学会
|
| 論文のバージョン | publisher
|
| 査読 |
有り
|
| Eprints Journal Name | joma
|
