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JaLCDOI 10.18926/15518
タイトル(別表記) Clinical significance of spa therapy in patients with steroid-dependent intractable asthma
フルテキストURL 065_119_127.pdf
著者 谷崎 勝朗| 貴谷 光| 御舩 尚志| 光延 文裕| 梶本 和宏| 横田 聡| 高田 一郎|
抄録 気管支喘息のなかでも,副腎皮質ホルモン依存性の喘息は,もっとも重症難治性であり,薬物療法のみでコントロールすることは極めて困難である。著者らの現在までの成績では,このようなステロイド依存性重症難治性喘息に対して,温泉療法は有効であった。このことは,喘息の治療,とりわけ重症難治例の治療には温泉療法が必要不可欠であることを示している。今回は,その臨床的有用性および機序について,若干の考察を加えた。1.臨床病型では,Ib型やII型に重症難治症例が多く,温泉療法はこれらの病型に対して有効であった。2.年齢別検討では,発症年齢では30才以上,また現年齢では40才以上の症例に対して温泉療法は有効であった。3.温泉療法による換気機能の改善では,小ないし細気管支領域の閉塞の改善がより高度であった。4.温泉療法により,気道過敏性が低下することが観察された。5.温泉療法により,高度に低下した副腎皮質機能の改善が見られた。5.ヨードゾル吸入,鉱泥湿布療法,温泉プール水泳ないし歩行訓練などが,喘息の治療に適した温泉療法と判断された。
キーワード 重症難治性喘息 (intractable asthma) 換気機能 (ventilatory function) ヨードゾル吸入 (inhalation of iodine salt solution) 鉱泥湿布療法 (fango therapy) 温泉プール水泳訓練 (swimming training in a hot spring pool)
出版物タイトル 岡大三朝分院研究報告
発行日 1994-09
65巻
開始ページ 119
終了ページ 127
ISSN 0918-7839
言語 日本語
論文のバージョン publisher
NAID 120002307310
著者 松原 扶美恵| 井上 妙子| 貴谷 光| 谷崎 勝朗|
発行日 1994-09
出版物タイトル 岡大三朝分院研究報告
65巻
資料タイプ データ・データベース
著者 岡山大学医学部附属病院三朝分院|
発行日 1994-09
出版物タイトル 岡大三朝分院研究報告
65巻
資料タイプ その他
JaLCDOI 10.18926/15495
フルテキストURL Mem_Fac_Eng_OU_24_2_31.pdf
著者 岡 久雄| Isayama Yoshiharu| Nakauchi Makoto| 山本 辰馬|
抄録 A small vibration on the body surface is expected to apply to a clinical examination of the autonomic nervous system. The vibration cannot be found by the naked eyes. It is called a microvibration (MV) or a minor tremor (MT). It is not cleared out why and how the MV occurs, but many papers about its occurrence and clinical application have been published. In this study, the typical spectrum of MV and the various causes of MV occurrence are studied. The relationships of MV with heart rate, muscle contraction and MV are discussed. The power spectrum of MV is obtained by using an autoregressive model.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 1990-03-29
24巻
2号
開始ページ 31
終了ページ 40
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120002307725
JaLCDOI 10.18926/15479
フルテキストURL Mem_Fac_Eng_OU_24_1_73.pdf
著者 岡 久雄| Isayama Yoshiharu| 山本 尚武| 山本 辰馬|
抄録 There is a small vibration which goes undetected by the naked eyes. It is called a microvibration (MV) or a minor tremor (MT). The MV on the body surface is expected to apply to a clinical examination of the autonomic nervous system. It is not cleared why and how the MV occurs, but there are many papers about its occurrence and clinical application. In this study, MV measuring system, its estimation and basic characteristics are examined. The difference between head MV and thenar MV, individual MV and diurnal and seasonal change are discussed. The power spectrum of MV is obtained using an autoregressive model.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 1989-11-29
24巻
1号
開始ページ 73
終了ページ 80
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120002307633
JaLCDOI 10.18926/15476
フルテキストURL Mem_Fac_Eng_OU_24_1_63.pdf
著者 山本 尚武| Isshiki Hiromi| 岡 久雄| 山本 辰馬|
抄録 There is no doubt that many people feel the peace of mind or the pleasures of senses in appreciating music. But the estimation of the effect is very difficult and the objective estimation can be hardly done. This study proposed the objective estimating method of human emotion utilizing galvanic skin reflex (GSR) which reflects a human psychological activity. In this method, not by individual response, but by the series of response and pattern of appearance of GSR, the emotional response under appreciating music was investigated. In the case of appreciation of the same classic music to several subjects, the individual GSR responses are random and remarkable characteristic could not be find on the results. However, on the patterns of appearance of GSR, the patterns obtaining from the same generation are much similar each other and the patterns obtaining from different generation are less similar. It was cleared that the same music gave different effect on different generations.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 1989-11-29
24巻
1号
開始ページ 63
終了ページ 72
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120002307670
JaLCDOI 10.18926/15465
フルテキストURL Mem_Fac_Eng_OU_23_1_49.pdf
著者 岡 久雄| 山本 辰馬| Isayama Yoshiharu|
抄録 In the field of dental study it is most fundamental and necessary to estimate the condition of periodontium. In order to examine a mechanical characteristics of periodontium, the theoretical displacement response to periodontal mechanical model (three elements model) are strictly solved in case of some pulse excitations. Impact excitations (rectangular, triangular and half-cycle sine pulse) are given in physical and mathematical definitions and complete solutions to the impact excitations are provided. The triangular pulse excitation which is obtained by means of a fracture of pencil-lead is most suitable. The mechanical parameters of periodontium are given using this input excitation. This is experimentally confirmed by artificial tooth model. The obtained mechanical characteristic of the periodontal tissues can be applied to clinical diagnosis.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 1988-11-22
23巻
1号
開始ページ 49
終了ページ 60
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120002307622
JaLCDOI 10.18926/15446
フルテキストURL Mem_Fac_Eng_OU_22_1.pdf
著者 岡 久雄| 山本 辰馬|
抄録 Biomechanical impedance is relatively small compared to industrial mechanical impedance. Thus it is difficult to measure it precisely. A biomechanical impedance measuring system was developed for portable use by means of random excitation. This system doesn't require a fixed body and vibrator supporting apparatus. In order to obtain an impedance spectrum, the FFT processing is performed using a personal computer. The spectra of the biomechanical impedance which is measured on body surfaces depend on body positions and can be roughly classified into three spectra patterns : soft, stiff and intermediate. During the measurement, the measuring conditions (preload, diameter of the vibrating tip etc.) influence the results. However, it became clear that the linearity of the biomechanical impedance was satisfied in the limited measuring conditions. Accordingly it is possible to standardize the impedance and to compare it with the results under different measuring conditions.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 1988-03-31
22巻
開始ページ 1
終了ページ 14
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120002307480
JaLCDOI 10.18926/15417
フルテキストURL Mem_Fac_Eng_OU_29_2_39.pdf
著者 岡 久雄| 坂本 俊哉| Irie Takashi|
抄録 The body structures under the skin surface, such as bones and tendon, have an influence on the stiffness evaluation observed from the surface. In this case, the observed stiffness should be called an apparent stiffness. To obtain the biomechanical properties of skin itself, the influence of body structure should be removed. This study deals with the correction method of apparent viscoelasticity which calculated from apparent biomechanical impedance. This method is applied to the measured result of the forearm and the right chest to confirm its effectiveness.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 1995-03-27
29巻
2号
開始ページ 39
終了ページ 47
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120002307527
JaLCDOI 10.18926/15415
フルテキストURL Mem_Fac_Eng_OU_29_2_29.pdf
著者 岡 久雄| 福田 敬|
抄録 In the stiffness evaluation from the skin surface, the body structure under the skin, like a bone and muscle, influences on the measurement results. The authors developed the measurement system of biomechanical impedance with applying a vibration of acoustic frequency onto the body surface. We measured the viscoelasticity of the silicone-gel model, which involves metal blocks, from the gel surface by using this system. The internal structure of model is estimated from the relation between the viscoelasticity and the distance from the gel surface to the internal block. Applying this method, the shape of ribs of the right chest are estimated. The shapes and viscoelasticity of silicone-gel tumor model, which has two different tumors, are also estimated.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 1995-03-27
29巻
2号
開始ページ 29
終了ページ 37
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120002307199
JaLCDOI 10.18926/15400
フルテキストURL Mem_Fac_Eng_OU_27_2_11.pdf
著者 岡 久雄| 山本 辰馬| Saratani Keiji| Tanaka Masahiro| Kawazoe Takayoshi|
抄録 The use of dental implants has increased together with increases in the human life span and it has become an imperative subject for dentists to familiarize themselves with this treatment modality. Unfortunately, there has been no practical and quantitative method for in vivo evaluation of the stability of dental implants. In the tooth mobility examination, the tactile sense of natural teeth is different from that of dental implants. The authors have developed an automatic diagnosis system of tooth mobility for clinical use. The biomechanical mobility of peri-implantium is measured with a pseudo-random vibration, from which the viscoelasticity c1, c2, k of peri-implantium is obtained. The diagnosis system has been applied to the quantitative evaluation of the stability of implants : endodontics endosseous implants (titanium pin), endosseous implants (Bioceram). It has also been applied to the evaluation of the long-term prognoses of dental implantation (Bioceram) and the examination of Intramobile implant (IMZ), and the satisfactory results have been obtained.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 1993-03-25
27巻
2号
開始ページ 11
終了ページ 17
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120002308018
JaLCDOI 10.18926/15393
フルテキストURL Mem_Fac_Eng_OU_30_2_15.pdf
著者 岡 久雄| 藤原 史朗|
抄録 An estimation of muscle fatigue is very important study and many laboratory researchers had done actively in this field. The excellent measurement and analysis methods, however, have not established yet. The aim of this study was to investigate the muscle fatigue of low back, caused by sitting on the vehicle seat for a long time. The muscle viscoelasticity and the EMG (Electromyogram) were measured. The authors proposed the objective muscle fatigue index that was obtained from the result of PCA (Principal Component Analysis) by using the measured varlables. The objective muscle fatigue index suggests an adequate correlation with the subjective fatigue on the vehicle seat.
出版物タイトル Memoirs of the Faculty of Engineering, Okayama University
発行日 1996-03-29
30巻
2号
開始ページ 15
終了ページ 20
ISSN 0475-0071
言語 英語
論文のバージョン publisher
NAID 120002307965
著者 田熊 正栄| 増井 悦子| 林本 加奈枝| 浅海 昇| 立花 英夫| 越智 浩二| 原田 英雄|
発行日 1991-08
出版物タイトル 環境病態研報告
62巻
資料タイプ その他
著者 岡山大学医学部附属病院三朝分院|
発行日 1992-06
出版物タイトル 岡大三朝分院研究報告
63巻
資料タイプ その他
著者 松原 扶美恵| 遠藤 裕井| 貴谷 光| 谷崎 勝朗|
発行日 1992-06
出版物タイトル 岡大三朝分院研究報告
63巻
資料タイプ データ・データベース
著者 三朝分院看護部|
発行日 1992-06
出版物タイトル 岡大三朝分院研究報告
63巻
資料タイプ その他
JaLCDOI 10.18926/15345
タイトル(別表記) 気管支喘息の発症における加齢の影響について
フルテキストURL 063_142_147.pdf
著者 光延 文裕| 貴谷 光| 岡崎 守宏| 御舩 尚志| 谷崎 勝朗|
抄録 Skin tests, serum total IgE levels, specific IgE antibodies against each allergen, bronchial reactions provoked by allergens and histamine release from basophils are well known as prameters of immediate allergic reactions. The incidence of positive immediate skin reaction to allergens such as house dust, ragweed, Aspergillus Alternaria, Cladosporium and Broncasma decreased with aging. On the other hand, the incidence of positive skin reaction to Candida albicans was higher in cases between the age of 41 and 50 and cases over the age of 61 compared to that in the other groups classified by age. Serum IgE levels was highest in cases aged between 0 and 30. The levels of serum IgE decreased with aging. The incidence of positive RAST scores (more than 2+) and positive bronchial reaction to house dust were highest in cases between 0 and 30, and decreased with aging. However, the positive ratio of these tests against C. albicans were highest in cases between 41 and 50. The degree of histamine release from basophils of asthmatics induced by anti-IgE was consistently high without any correlation to aging when their serum IgE levels were more than 501 IU/ml. In the cases with serum IgE levels of less than 300 IU/ml, basophil reactivity to anti-IgE decreasd with aging. Basophil reactivity to house dust was generally dependent on the levels of specific IgE antibodies against the allergen. Although basophil reactivity to C. albicans was also high in cases with positive RAST scores, some cases with a RAST score of 0+ or 1+ showed high or moderate basophil reactivity. Moderate or high reactivity of basophils was frequently observed in cases between 41 and 50 and cases over age 61.
キーワード Skin test (皮内反応) IgE Provocation test (吸入誘発試験) Basophil reactivity (好塩基球の反応性) Aging (加齢)
出版物タイトル 岡大三朝分院研究報告
発行日 1992-06
63巻
開始ページ 142
終了ページ 147
ISSN 0913-3771
言語 英語
論文のバージョン publisher
NAID 120002307130
JaLCDOI 10.18926/15343
タイトル(別表記) 抗原および抗ヒトIgEに対する抗塩基球の反応性. 3.Ca2(+)の細胞内流入およびヒスタミン遊離
フルテキストURL 063_134_141.pdf
著者 谷崎 勝朗| 貴谷 光| 岡崎 守宏| 御舩 尚志| 光延 文裕| 木村 郁郎|
抄録 The release mechanism of chemical mediators from basophils and mast cells was discussed when these cells were stimulated by different antigens and anti-IgE. 1. Ca(2+) influx into mast cells increased after stimulation by antigen. The increased Ca(2+) uptake by mast cells was inhibited by antiallergic agents, disodium cromoglycate (DSCG) and tranilast, and calcium antagonists, nifedipine and nicardipine. 2. The dose-response curve of histamine release by antigen was different from that by anti-IgE. The maximum release of histamine by house dust was, however, similar to that by anti-IgE. House dust- and anti-IgE-induced release of histamine increased with higher- serum IgE levels. On the contrary, the release of histamine by Candida albicans was not releated to serum IgE levels, and the release by C. albicans did not parallel therelease by anti-IgE.
キーワード Ca(2+) influx (Ca2+流入) histamine release (ヒスタミン遊離) house dust (ハウスダスト) Candida albicans (カンジダ) anti-lgE (抗ヒトIgE)
出版物タイトル 岡大三朝分院研究報告
発行日 1992-06
63巻
開始ページ 134
終了ページ 141
ISSN 0913-3771
言語 英語
論文のバージョン publisher
NAID 120002307872
著者 岡山大学医学部附属病院三朝分院|
発行日 1993-06
出版物タイトル 岡大三朝分院研究報告
64巻
資料タイプ その他
JaLCDOI 10.18926/15341
タイトル(別表記) 抗原および抗ヒトIgEに対する好塩基球の反応性. 2.分泌機序における形態的変化
フルテキストURL 063_128_133.pdf
著者 谷崎 勝朗| 高橋 清| 木村 郁郎|
抄録 Morphological changes of blood basophils activated by antigen and anti-IgE were discussed in relation to release mechanisms of the cells. 1. Basophils activated by antigen and anti-IgE show two different types : A form (pear-shaped) and B from (swollen type), on smear preparartions. 2. Pear-shaped basophils(reactive basophils), which appear after stimulation by antigen and anti-IgE, can be observed by the staining solution for the direct count of basophils and eosinophils. 3. The incidence of reactive basophils increases after addition of antigen. Thus, observation of reactive basophils can be clinically applied for detecting allergen (DCRB ; direct connt of reactive basophils). 4. Observation of morphological basophil response by phase- contrast microscopic motion pictures demonstrates that basophils activated by antigen show two different reponses, increase in motility (oriented movement) and degranulation.
キーワード morphological changes of basophils (好塩基球の形態的変化) reactive basophils (反応好塩基球) degranulation (脱顆粒) histamine release (ヒスタミン遊離)
出版物タイトル 岡大三朝分院研究報告
発行日 1992-06
63巻
開始ページ 128
終了ページ 133
ISSN 0913-3771
言語 英語
論文のバージョン publisher