検索結果 - 岡山大学学術成果リポジトリ

Risk Factors for Low Bone Mineral Density Determined in Patients in a General Practice Setting

JaLCDOI	10.18926/AMO/57370
フルテキストURL	73_5_403.pdf
著者	Ando, Akemi\| Mitsuhashi, Toshiharu\| Honda, Mitsugi\| Hanayama, Yoshihisa\| Hasegawa, Kou\| Obika, Mikako\| Kataoka, Hitomi\| Otsuka, Fumio\|
抄録	Osteoporosis increases the risk of bone fractures. It is diagnosed based on an individual’s bone mineral density (BMD) or a fracture without trauma. BMD is usually measured by the dual energy X-ray absorptiometry (DXA) method. Here we investigated factors for the earliest possible prediction of decreased BMD by examining the relationships between patients’ BMD values and changes in the patients’ physical and laboratory values. We retrospectively reviewed the medical records of 149 patients who visited our department in 2014-2015 for a variety of reasons and underwent an area BMD examination by DXA. We analyzed the relationships between decreasing BMD and the patients’ gender, age, body mass index (BMI), medical background, hemoglobin, electrolytes, and thyroid function. Thirty-nine of the patients were diagnosed with osteoporosis based on their T-scores. An adjusted analysis showed that female gender, aging, and increased serum calcium level were significantly related to decreasing femoral BMD, whereas high BMI was associated with an increase in femoral BMD. Collectively the results indicate that for the early detection of low BMD, it is important for general-practice physicians to consider conducting a BMD checkup when treating female and elderly patients with a low BMI and/or elevated serum calcium level.
キーワード	bone mineral density (BMD) body mass index (BMI) female gender hypercalcemia osteoporosis
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-10
巻	73巻
号	5号
出版者	Okayama University Medical School
開始ページ	403
終了ページ	411
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31649366
Web of Science KeyUT	000491886600005

The Role of High Mobility Group Box-1 in Epileptogenesis

JaLCDOI	10.18926/AMO/57367
フルテキストURL	73_5_383.pdf
著者	Fu, Li\| Nishibori, Masahiro\|
抄録	High mobility group box-1 (HMGB1) is a non-histone, DNA-binding nuclear protein belonging to the family of damage-associated molecular patterns (DAMPs). HMGB1 has been reported to play an important role during epileptogenesis although the mechanisms of its actions are still not clear. Many hypotheses have been suggested especially about the relationship between HMGB1 and inflammation responses and blood-brain barrier disruption during epileptogenesis. In this review, we will mainly discuss the role of HMGB1 in epileptogenesis.
キーワード	HMGB1 epileptogenesis inflammation blood-brain barrier
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2019-10
巻	73巻
号	5号
出版者	Okayama University Medical School
開始ページ	383
終了ページ	386
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31649363
Web of Science KeyUT	000491886600002

Histidine-rich Glycoprotein Modulates the Blood-vascular System in Septic Condition

JaLCDOI	10.18926/AMO/57366
フルテキストURL	73_5_379.pdf
著者	Wake, Hidenori\|
抄録	Histidine-rich glycoprotein (HRG) is a 75 kDa glycoprotein synthesized in the liver whose plasma concentration is 100-150 μg/ml. HRG has been shown to modulate sepsis-related biological reactions by binding to several substances and cells, including heparin, factor XII, fibrinogen, thrombospondin, plasminogen, C1q, IgG, heme, LPS, dead cells, bacteria, and fungi. Therefore, reduction of plasma HRG levels in sepsis leads to dysregulation of coagulation, fibrinolysis, and immune response, resulting in disseminated intravascular coagulation and multiple organ failure. This review summarizes the binding and functional properties of HRG in sepsis.
キーワード	htidine-rich glycoprotein septic pathogenesis immunothrombosis
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2019-10
巻	73巻
号	5号
出版者	Okayama University Medical School
開始ページ	379
終了ページ	382
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31649362
Web of Science KeyUT	000491886600001

Breastfeeding and risk of food allergy: A nationwide birth cohort in Japan

フルテキストURL	Allergol_Int_201908007.pdf
著者	Matsumoto, Naomi\| Yorifuji, Takashi\| Nakamura, Kazue\| Ikeda, Masanori\| Tsukahara, Hirokazu\| Doi, Hiroyuki\|
キーワード	Breastfeeding Cohort Colostrum Eczema Food allergy
発行日	2019-09-17
出版物タイトル	Allergology International
出版者	Elsevier
ISSN	13238930
NCID	AA11091750
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 Japanese Society of Allergology. Production and hosting by Elsevier B.V.
論文のバージョン	publisher
PubMed ID	31540813
DOI	10.1016/j.alit.2019.08.007
関連URL	isVersionOf https://doi.org/10.1016/j.alit.2019.08.007

Biochemical outcomes and predictive factors by risk group after permanent iodine-125 seed implantation: Prospective cohort study in 2,316 patients

フルテキストURL	fulltext.pdf
著者	Katayama, Norihisa\| Nakamura, Katsumasa\| Yorozu, Atsunori\| Kikuchi, Takashi\| Fukushima, Masanori\| Saito, Shiro\| Dokiya, Takushi\|
キーワード	Biochemical failure Brachytherapy External beam radiation therapy Predictive factors Prostate cancer Risk group
発行日	2019-10-31
出版物タイトル	Brachytherapy
巻	18巻
号	5号
出版者	Elsevier
開始ページ	574
終了ページ	582
ISSN	15384721
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.
論文のバージョン	author
PubMed ID	31153759
DOI	10.1016/j.brachy.2019.03.008
Web of Science KeyUT	000487173400002
関連URL	isVersionOf https://doi.org/10.1016/j.brachy.2019.03.008

Long-term safety and pharmacodynamics of mepolizumab in children with severe asthma with an eosinophilic phenotype

フルテキストURL	JAllergyClin Immunol_144_5_1336.pdf
著者	Gupta, Atul\| Ikeda, Masanori\| Geng, Bob\| Azmi, Jay\| Price, Robert G.\| Bradford, Eric S.\| Yancey, Steven W.\| Steinfeld, Jonathan\|
キーワード	Pediatric asthma eosinophilia mepolizumab
発行日	2019-08-16
出版物タイトル	Journal of Allergy and Clinical Immunology
巻	144巻
号	5号
開始ページ	1336
終了ページ	1342
ISSN	00916749
NCID	AA00692442
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.
論文のバージョン	publisher
PubMed ID	31425781
DOI	10.1016/j.jaci.2019.08.005
関連URL	isVersionOf https://doi.org/10.1016/j.jaci.2019.08.005

Posttraumatic cartilage degradation progresses following anterior cruciate ligament reconstruction: A second-look arthroscopic evaluation

フルテキストURL	JOS24_6_1058.pdf Figs.pdf Table.pdf
著者	Hiranaka, Takaaki\| Furumatsu, Takayuki\| Kamatsuki, Yusuke\| Sugiu, Kazuhisa\| Okazaki, Yoshiki\| Masuda, Shin\| Okazaki, Yuki\| Takihira, Shota\| Miyazawa, Shinichi\| Nakata, Eiji\| Ozaki, Toshifumi\|
備考	This fulltext will be available in Nov 2020 \|
発行日	2019-08-20
出版物タイトル	Journal of Orthopaedic Science
巻	24巻
号	6号
出版者	Elsevier
開始ページ	1058
終了ページ	1063
ISSN	09492658
NCID	AA11052566
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.
論文のバージョン	author
PubMed ID	31444009
DOI	10.1016/j.jos.2019.08.001
Web of Science KeyUT	000496202800019
関連URL	isVersionOf https://doi.org/10.1016/j.jos.2019.08.001

Effectiveness and safety of low-concentrated ozonized water for the reduction of contamination in dental unit water lines

フルテキストURL	Heliyon_5_8_02306.pdf
著者	Okubo, Keisuke\| Ito, Takashi\| Shiota, Yasuyoshi\| Kawata, Yusuke\| Yamamoto, Tadashi\| Takashiba, Shogo\|
キーワード	Biofilm Dental chair unit water line (DUWL) Heterotrophic bacteria Low-concentration Materials science Ozonized water
発行日	2019-08-31
出版物タイトル	Heliyon
巻	5巻
号	8号
出版者	Elsevier Science
開始ページ	e02306
ISSN	24058440
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 The Authors. Published by Elsevier Ltd.
論文のバージョン	publisher
PubMed ID	31463403
DOI	10.1016/j.heliyon.2019.e02306
Web of Science KeyUT	000484391200055
関連URL	isVersionOf https://doi.org/10.1016/j.heliyon.2019.e02306

Clinical and Pathological Benefit of Twendee X in Alzheimer's Disease Transgenic Mice with Chronic Cerebral Hypoperfusion

フルテキストURL	JSCD28_7_1993.pdf Fig.pdf
著者	Liu, Xia\| Yamashita, Toru\| Shang, Jingwei\| Shi, Xiaowen\| Morihara, Ryuta\| Huang, Yong\| Sato, Kota\| Takemoto, Mami\| Hishikawa, Nozomi\| Ohta, Yasuyuki\| Abe, Koji\|
キーワード	APP23 mice Alzheimer's disease anti-inflammatory antioxidative chronic cerebral hypoperfusion
発行日	2019-07-31
出版物タイトル	Journal of Stroke and Cerebrovascular Diseases
巻	28巻
号	7号
出版者	Elsevier
開始ページ	1993
終了ページ	2002
ISSN	10523057
NCID	AA10780852
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	31029568
DOI	10.1016/j.jstrokecerebrovasdis.2019.03.029
Web of Science KeyUT	000470969200037
関連URL	isVersionOf https://doi.org/10.1016/j.jstrokecerebrovasdis.2019.03.029

Layer-specific expression of extracellular matrix molecules in the mouse somatosensory and piriform cortices

フルテキストURL	fulltext.pdf
著者	Ueno, Hiroshi\| Suemitsu, Shunsuke\| Murakami, Shinji\| Kitamura, Naoya\| Wani, Kenta\| Matsumoto, Yosuke\| Okamoto, Motoi\| Ishihara, Takeshi\|
キーワード	Extracellular matrix Perineuronal nets Piriform cortex Proteoglycans Somatosensory cortex Wisteria floribunda
発行日	2019-06
出版物タイトル	IBRO Reports
巻	6巻
出版者	Elsevier
開始ページ	1
終了ページ	17
ISSN	24518301
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2018 The Authors.
論文のバージョン	publisher
PubMed ID	30582064
DOI	10.1016/j.ibror.2018.11.006
関連URL	isVersionOf https://doi.org/10.1016/j.ibror.2018.11.006

Vision evaluation by functional observational battery, operant behavior test, and light/dark box test in retinal dystrophic RCS rats versus normal rats

フルテキストURL	Heliyon_5_6_01936.pdf
著者	Matsuo, Toshihiko\| Uchida, Tetsuya\| Yamashita, Koichiro\| Takei, Shigiko\| Ido, Daisuke\| Fujiwara, Atsushi\| Iino, Masahiko\| Oguchi, Masao\|
キーワード	Bioengineering Neuroscience Physiology Zoology
発行日	2019-06-30
出版物タイトル	Heliyon
巻	5巻
号	6号
出版者	Elsevier Science
開始ページ	e01936
ISSN	24058440
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 The Authors.
論文のバージョン	publisher
PubMed ID	31294104
DOI	10.1016/j.heliyon.2019.e01936
Web of Science KeyUT	000473818300195
関連URL	isVersionOf https://doi.org/10.1016/j.heliyon.2019.e01936

Second nationwide surveillance of bacterial pathogens in patients with acute uncomplicated cystitis conducted by Japanese Surveillance Committee from 2015 to 2016: antimicrobial susceptibility of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus saprophyticus

フルテキストURL	fulltext.pdf
著者	Hayami, Hiroshi\| Takahashi, Satoshi\| Ishikawa, Kiyohito\| Yasuda, Mitsuru\| Yamamoto, Shingo\| Wada, Koichiro\| Kobayashi, Kanao\| Hamasuna, Ryoichi\| Minamitani, Shinichi\| Matsumoto, Tetsuya\| Kiyota, Hiroshi\| Tateda, Kazuhiro\| Sato, Junko\| Hanaki, Hideaki\| Masumori, Naoya\| Nishiyama, Hiroyuki\| Miyazaki, Jun\| Fujimoto, Kiyohide\| Tanaka, Kazushi\| Uehara, Shinya\| Matsubara, Akio\| Ito, Kenji\| Hayashi, Kenji\| Kurimura, Yuichiro\| Ito, Shin\| Takeuchi, Toshimi\| Narita, Harunori\| Izumitani, Masanobu\| Nishimura, Hirofumi\| Kawahara, Motoshi\| Hara, Makoto\| Hosobe, Takahide\| Takashima, Kenji\| Chokyu, Hirofumi\| Matsumura, Masaru\| Ihara, Hideari\| Uno, Satoshi\| Monden, Koichi\| Sumii, Toru\| Kawai, Shuichi\| Kariya, Satoru\| Sato, Takashi\| Yoshioka, Masaru\| Kadena, Hitoshi\| Matsushita, Shinji\| Nishi, Shohei\| Hosokawa, Yukinari\| Shirane, Takeshi\| Yoh, Mutsumasa\| Watanabe, Syuji\| Makinose, Shinichi\| Uemura, Tetsuji\| Goto, Hirokazu\|
キーワード	Surveillance Susceptibility Resistance Acute uncomplicated cystitis
発行日	2019-06
出版物タイトル	Journal of Infection and Chemotherapy
巻	25巻
号	6号
出版者	Elsevier
開始ページ	413
終了ページ	422
ISSN	1341-321X
NCID	AA11057978
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2019 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases.
論文のバージョン	publisher
PubMed ID	30905628
DOI	10.1016/j.jiac.2019.02.021
Web of Science KeyUT	000466427000002
関連URL	isVersionOf https://doi.org/10.1016/j.jiac.2019.02.021

Early childhood exposure to maternal smoking and Kawasaki Disease: A longitudinal survey in Japan

フルテキストURL	SciTotalEnviron_201811194.pdf
著者	Yorifuji, Takashi\| Tsukahara, Hirokazu\| Doi, Hiroyuki\|
キーワード	Early childhood exposure Epidemiology Mucocutaneous lymph node syndrome; Smoking
発行日	2019-03-10
出版物タイトル	Science of The Total Environment
巻	655巻
出版者	Elsevier
開始ページ	141
終了ページ	146
ISSN	00489697
NCID	AA00836666
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	30469059
DOI	10.1016/j.scitotenv.2018.11.194
Web of Science KeyUT	000455034600013
関連URL	isVersionOf https://doi.org/10.1016/j.scitotenv.2018.11.194

Injury patterns of medial meniscus posterior root tears

フルテキストURL	OTSR105_1_107.pdf Fig.pdf
著者	Furumatsu, Takayuki\| Okazaki, Yuki\| Okazaki, Yoshiki\| Hino, Tomohito\| Kamatsuki, Yusuke\| Masuda, Shin\| Miyazawa, Shinichi\| Nakata, Eiji\| Hasei, Joe\| Kunisada, Toshiyuki\| Ozaki, Toshifumi\|
キーワード	Descending knee motion Injury pattern Medial meniscus Posterior root tear Squatting
発行日	2019-02-28
出版物タイトル	Orthopaedics & Traumatology: Surgery & Research
巻	105巻
号	1号
出版者	Elsevier
開始ページ	107
終了ページ	111
ISSN	18770568
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	30442555
DOI	10.1016/j.otsr.2018.10.001
Web of Science KeyUT	000456541300018
関連URL	isVersionOf https://doi.org/10.1016/j.otsr.2018.10.001

Outcomes of patients who developed subsequent solid cancer after hematopoietic cell transplantation

フルテキストURL	Blood advances 2018.pdf
著者	Inamoto, Yoshihiro\| Matsuda, Tomohiro\| Tabuchi, Ken\| Kurosawa, Saiko\| Nakasone, Hideki\| Nishimori, Hisakazu\| Yamasaki, Satoshi\| Doki, Noriko\| Iwato, Koji\| Mori, Takehiko\| Takahashi, Satoshi\| Yabe, Hiromasa\| Kohno, Akio\| Nakamae, Hirohisa\| Sakura, Toru\| Hashimoto, Hisako\| Sugita, Junichi\| Ago, Hiroatsu\| Fukuda, Takahiro\| Ichinohe, Tatsuo\| Atsuta, Yoshiko\| Yamashita, Takuya\| Japan Society for Hematopoietic Cell Transplantation Late Effects and Quality of Life Working Group\|
発行日	2018-08
出版物タイトル	Blood Advances
巻	2巻
号	15号
出版者	American Society of Hematology
開始ページ	1901
終了ページ	1903
ISSN	2473-9529
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	publisher
PubMed ID	30087108
DOI	10.1182/bloodadvances.2018020966
関連URL	isVersionOf https://doi.org/10.1182/bloodadvances.2018020966

To Be Supported, or Not to Be: Images of Older People in Policy and the Reality in Local Communities in Japan

フルテキストURL	Front_Sociol_201900016.pdf
著者	Aoo, Ken\| Abe, Noriko\| Kano, Mitsunobu R.\|
キーワード	social innovation local community older people welfare society social service
発行日	2019-03-12
出版物タイトル	Frontiers in Sociology
巻	4巻
開始ページ	16
ISSN	2297-7775
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	publisher
DOI	10.3389/fsoc.2019.00016
関連URL	isVersionOf https://doi.org/10.3389/fsoc.2019.00016

CACNA1A variants may modify the epileptic phenotype of Dravet syndrome

フルテキストURL	NeurobiolDis_50_209.pdf
著者	Ohmori, Iori\| Ouchida, Mamoru\| Kobayashi, Katsuhiro\| Jitsumori, Yoshimi\| Mori, Akiko\| Michiue, Hiroyuki\| Nishiki, Teiichi\| Ohtsuka, Yoko\| Matsui, Hideki\|
備考	CACNA1A variants contribute to severity of seizures in Dravet syndrome\|
発行日	2013-02
出版物タイトル	Neurobiology of disease
巻	50巻
出版者	Academic Press
開始ページ	209
終了ページ	217
ISSN	09699961
NCID	AA11645502
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	23103419
DOI	10.1016/j.nbd.2012.10.016
Web of Science KeyUT	000313758100023
関連URL	isVersionOf https://doi.org/10.1016/j.nbd.2012.10.016

A Case of Primary Colonic Signet Ring Cell Carcinoma in a Young Man which Preoperatively Mimicked Phlebosclerotic Colitis

JaLCDOI	10.18926/AMO/56939
フルテキストURL	73_4_361.pdf
著者	Watanabe, Ayako\| Kadowaki, Yoshihiko\| Hattori, Kenji\| Ohmori, Mika\| Tsukayama, Hiroyuki\| Kubota, Nobuhito\| Okumoto, Tatsuo\| Ishido, Nobuhiro\| Okino, Takeshi\|
抄録	A 35-year-old man was referred to our hospital for chronic abdominal pain and diarrhea. Computed tomography showed wall thickening, poor contrast enhancement and calcification of the ascending colon, which were consistent with phlebosclerotic colitis. Malignant character was not detected from a biopsy specimen. Operatively, we observed a scirrhous mass of the ascending colon invading surrounding tissue, which was diagnosed as signet ring cell carcinoma based on analysis of an intraoperative frozen section. Right hemicolectomy with regional lymph node dissection was performed. This case was extremely similar to phlebosclerotic colitis in clinical findings; surgical resection was required for correct diagnosis.
キーワード	phlebosclerotic colitis colorectal cancer signet ring cell carcinoma young colorectal cancer
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2019-08
巻	73巻
号	4号
出版者	Okayama University Medical School
開始ページ	361
終了ページ	365
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31439960

Significance of Microcalcifications on Mammography in the Surgical Treatment of Breast Cancer Patients with a Preoperative Diagnosis of Ductal Carcinoma in Situ by Core Needle Biopsy

JaLCDOI	10.18926/AMO/56937
フルテキストURL	73_4_349.pdf
著者	Isozaki, Hiroshi\| Yamamoto, Yasuhisa\| Murakami, Shigeki\| Matsumoto, Sasau\| Takama, Takehiro\|
抄録	To clarify the surgical outcomes of breast cancer patients with a preoperative diagnosis of ductal carcinoma in situ (DCIS) by core needle biopsy (CNB) (abbreviated as CNBDCIS), we retrospectively analyzed the cases of 131 patients with CNBDCIS who underwent surgery at Oomoto Hospital (32 total mastectomies, 99 conservative mastectomies). Our analysis of underestimation and predictors of invasive breast cancer of CNBDCIS revealed that the underestimation rate of CNBDCIS was 40.5% (53/131). A logistic regression analysis revealed that palpable tumors (yes to no, odds ratio [OR] 3.25), mammography (MMG) category group (category 4 or 5 to categories 1 , 2, or 3, OR 4.69) and MMG microcalcifications (no to yes, OR 0.24) were significant predictive factors for CNBDCIS invasion. In our analysis of the predictors of positive margins during CNBDCIS surgery, 36 (27.5%) of the 131 patients had positive margins after postoperative pathological examination. A logistic regression analysis revealed that the operative procedure (conservative surgery to total mastectomy, OR 21.4) and MMG microcalcifications (yes to no, OR 3.35) were significant factors related to positive margins during CNBDCIS surgery. Thus, MMG microcalcifications are a negative predictor of upgrading of CNBDCIS and a positive predictor of positive surgical margins for CNBDCIS.
キーワード	ductal carcinoma in situ core needle biopsy underestimation positive margins microcalcifications on mammography
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-08
巻	73巻
号	4号
出版者	Okayama University Medical School
開始ページ	349
終了ページ	356
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31439958

Therapeutic Outcomes of 15 Postoperative Bronchopleural Fistulas Including Seven Endoscopic Interventions

JaLCDOI	10.18926/AMO/56934
フルテキストURL	73_4_325.pdf
著者	Ueno, Tsuyoshi\| Maki, Yuho\| Sugimoto, Ryujiro\| Suehisa, Hiroshi\| Yamashita, Motohiro\| Harada, Daijiro\| Kozuki, Toshiyuki\| Nogami, Naoyuki\|
抄録	Therapeutic approaches to bronchopleural fistula (BPF) closure after lung resection are surgical or endoscopic interventions. We evaluated therapeutic outcomes to determine the optimal approach. We reviewed 15 patients who had developed BPF after lung resection for thoracic malignant diseases at our institution in the 10 years since 2008. The patients were 11 men and 4 women (mean age 68 years). We performed one pneumonectomy, 6 lobectomies, 7 segmentectomies, and one partial resection for malignant diseases. The median interval from lung resection to the BPF diagnosis was 46 days. The BPF-associated mortality rate was 26.7% (4/15). The rate of successful BPF closure was 66.6% (10/15). The endoscopic and surgical intervention success rates were 14.2% (1/7) and 69.2% (9/13), respectively (p<0.01). Of 5 patients who had failed BPF treatments, 4 died, and one transferred out without BPF closure. The therapeutic outcomes were related to preoperative comorbidities, performance status at the BPF diagnosis, time intervals from lung resection to BPF diagnosis, and presence of active pneumonia. The difference between endoscopic and surgical outcomes was nonsignificant, although the surgical intervention success rate was somewhat higher. The selection of endoscopic or surgical intervention for BPF does not significantly affect therapeutic outcomes.
キーワード	bronchopleural fistula endoscopic intervention surgical intervention
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2019-08
巻	73巻
号	4号
出版者	Okayama University Medical School
開始ページ	325
終了ページ	331
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2019 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	31439955