
検索結果 3241 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Amioka, Naofumi| Miyoshi, Toru| Yonezawa, Tomoko| Kondo, Megumi| Akagi, Satoshi| Yoshida, Masashi| Saito, Yukihiro| Nakamura, Kazufumi| Ito, Hiroshi| |
| キーワード | pemafibrate angiotensin II abdominal aortic aneurysm oxidative stress catalase |
| 発行日 | 2022-06-30 |
| 出版物タイトル | Frontiers In Cardiovascular Medicine |
| 巻 | 9巻 |
| 出版者 | Frontiers Media SA |
| 開始ページ | 904215 |
| ISSN | 2297-055X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 Amioka, Miyoshi, Yonezawa, Kondo, Akagi, Yoshida, Saito, Nakamura and Ito. |
| 論文のバージョン | publisher |
| PubMed ID | 35845076 |
| DOI | 10.3389/fcvm.2022.904215 |
| Web of Science KeyUT | 000826574900001 |
| 関連URL | isVersionOf https://doi.org/10.3389/fcvm.2022.904215 |
| フルテキストURL | fulltext20220720-3.pdf figure20220720-3.pdf |
|---|---|
| 著者 | Haruma, Jun| Sugiu, Kenji| Hoshika, Minori| Hiramatsu, Masafumi| Hishikawa, Tomohito| Murai, Satoshi| Nishi, Kazuhiko| Yamaoka, Yoko| Sato, Yu| Ebisudani, Yuki| Edaki, Hisanori| Kimura, Ryu| Date, Isao| |
| キーワード | Digital imaging and communications in medicine data Intracranial aneurysm Three-dimensional printing |
| 備考 | © 2021 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.wneu.2021.12.018] .| |
| 発行日 | 2022-3 |
| 出版物タイトル | World Neurosurgery |
| 巻 | 159巻 |
| 出版者 | Elsevier BV |
| 開始ページ | e113 |
| 終了ページ | e119 |
| ISSN | 1878-8750 |
| NCID | AA12469471 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 Elsevier Inc. |
| 論文のバージョン | author |
| PubMed ID | 34896354 |
| DOI | 10.1016/j.wneu.2021.12.018 |
| Web of Science KeyUT | 000820574500021 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.wneu.2021.12.018 |
| フルテキストURL | fulltext20220715-3.pdf |
|---|---|
| 著者 | Niman, Eito| Miyoshi, Kentaroh| Shiotani, Toshio| Toji, Tomohiro| Igawa, Takuro| Otani, Shinji| Okazaki, Mikio| Sugimoto, Seiichiro| Yamane, Masaomi| Toyooka, Shinichi| |
| キーワード | Lung transplantation (LTx) lung recruitment maneuver atelectasis protective procurement |
| 発行日 | 2022-07-12 |
| 出版物タイトル | Journal of Thoracic Disease |
| 出版者 | AME Publishing Company |
| ISSN | 2072-1439 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © Journal of Thoracic Disease. |
| 論文のバージョン | publisher |
| DOI | 10.21037/jtd-22-226 |
| Web of Science KeyUT | 000821133100001 |
| 関連URL | isVersionOf https://doi.org/10.21037/jtd-22-226 |
| フルテキストURL | fulltext20220715-2.pdf |
|---|---|
| 著者 | Asano, Takao| Shibata, Akihisa| Yokoo, Masanori| |
| キーワード | Endogenous business cycles Technology choice Quasi-periodic motion OLG model Rotation number |
| 備考 | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s11071-022-07643-9 This fulltext is available in June 2023.| |
| 発行日 | 2022-06-29 |
| 出版物タイトル | Nonlinear Dynamics |
| 巻 | 110巻 |
| 号 | 1号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 945 |
| 終了ページ | 961 |
| ISSN | 0924-090X |
| NCID | AA10862447 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s), under exclusive licence to Springer Nature B.V. 2022 |
| 論文のバージョン | author |
| DOI | 10.1007/s11071-022-07643-9 |
| Web of Science KeyUT | 000818618400008 |
| 関連URL | isVersionOf https://doi.org/10.1007/s11071-022-07643-9 |
| フルテキストURL | fulltext20220708-4.pdf nep-supinfo.pdf |
|---|---|
| 著者 | Tsuji, Kenji| Kitamura, Shinji| Uchida, Haruhito A.| Wada, Jun| |
| キーワード | Renal biopsy clinical nephrology ultrasound |
| 備考 | This is the peer reviewed version of the following article: [Tsuji, K, Kitamura, S, Uchida, HA, Wada, J. Simulation for ultrasound-guided renal biopsy using boiled egg. Nephrology. 2022; 27( 9): 753- 757. doi:10.1111/nep.14079], which has been published in final form at [https://doi.org/10.1111/nep.14079]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. This fulltext is available in June 2023.| |
| 発行日 | 2022-06-28 |
| 出版物タイトル | Nephrology |
| 巻 | 27巻 |
| 号 | 9号 |
| 出版者 | Wiley |
| 開始ページ | 753 |
| 終了ページ | 757 |
| ISSN | 1320-5358 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 Asian Pacific Society of Nephrology. |
| 論文のバージョン | author |
| PubMed ID | 35762140 |
| DOI | 10.1111/nep.14079 |
| Web of Science KeyUT | 000816988200001 |
| 関連URL | isVersionOf https://doi.org/10.1111/nep.14079 |
| フルテキストURL | fulltext20220708-2.pdf |
|---|---|
| 著者 | Koyama, Toshihiro| Higashionna, Tsukasa| Maruo, Akinori| Ushio, Soichiro| Zamami, Yoshito| Harada, Ko| Hagiya, Hideharu| |
| キーワード | aging centenarians death nursing home trend |
| 備考 | This is the peer reviewed version of the following article: [Koyama, T, Higashionna, T, Maruo, A, et al. Trends in places and causes of death among centenarians in Japan from 2006 to 2016. Geriatr. Gerontol. Int. 2022; 22: 675– 680. https://doi.org/10.1111/ggi.14416], which has been published in final form at [https://doi.org/10.1111/ggi.14416]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| 発行日 | 2022-06-23 |
| 出版物タイトル | Geriatrics and Gerontology International |
| 巻 | 22巻 |
| 号 | 8号 |
| 出版者 | Wiley |
| 開始ページ | 675 |
| 終了ページ | 680 |
| ISSN | 1444-1586 |
| NCID | AA1155729X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 Japan Geriatrics Society. |
| 論文のバージョン | author |
| PubMed ID | 35739616 |
| DOI | 10.1111/ggi.14416 |
| Web of Science KeyUT | 000814866800001 |
| 関連URL | isVersionOf https://doi.org/10.1111/ggi.14416 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Wang, Jin| Sakai, Kenji| Kiwa, Toshihiko| |
| キーワード | rational design odorant-binding protein peptide SARS-CoV-2 volatile organic compounds computational tools |
| 発行日 | 2022-06-18 |
| 出版物タイトル | Molecules |
| 巻 | 27巻 |
| 号 | 12号 |
| 出版者 | MDPI |
| 開始ページ | 3917 |
| ISSN | 1420-3049 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 35745038 |
| DOI | 10.3390/molecules27123917 |
| Web of Science KeyUT | 000818390600001 |
| 関連URL | isVersionOf https://doi.org/10.3390/molecules27123917 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yasui, Tatsuya| Tanaka, Takuro| Malik, Asad| Kuribayashi, Minoru| |
| キーワード | watermarking pruning attack DNN model constant weight code fine-tuning |
| 発行日 | 2022-05-26 |
| 出版物タイトル | Journal Of Imaging |
| 巻 | 8巻 |
| 号 | 6号 |
| 出版者 | MDPI |
| 開始ページ | 152 |
| ISSN | 2313-433X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 35735951 |
| DOI | 10.3390/jimaging8060152 |
| Web of Science KeyUT | 000817529200001 |
| 関連URL | isVersionOf https://doi.org/10.3390/jimaging8060152 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Muzembo, Basilua Andre| Kitahara, Kei| Mitra, Debmalya| Ohno, Ayumu| Miyoshi, Shin-Ichi| |
| キーワード | cholera antibodies vibriocidal cholera toxin B lipopolysaccharide immunoglobulin immunity waning |
| 発行日 | 2022-06-10 |
| 出版物タイトル | International Journal of Environmental Research and Public Health |
| 巻 | 19巻 |
| 号 | 12号 |
| 出版者 | MDPI |
| 開始ページ | 7141 |
| ISSN | 1660-4601 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 35742404 |
| DOI | 10.3390/ijerph19127141 |
| Web of Science KeyUT | 000817347300001 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijerph19127141 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Kodera, Yuta| Sato, Ryoichi| Ali, Md Arshad| Kusaka, Takuya| Nogami, Yasuyuki| |
| キーワード | true random number generator ring oscillator Markov process hypothesis testing |
| 発行日 | 2022-05-31 |
| 出版物タイトル | Entropy |
| 巻 | 24巻 |
| 号 | 6号 |
| 出版者 | MDPI |
| 開始ページ | 780 |
| ISSN | 1099-4300 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 35741501 |
| DOI | 10.3390/e24060780 |
| Web of Science KeyUT | 000816552500001 |
| 関連URL | isVersionOf https://doi.org/10.3390/e24060780 |
| JaLCDOI | 10.18926/AMO/63744 |
|---|---|
| フルテキストURL | 76_3_333.pdf |
| 著者 | Akagawa, Manabu| Miyakoshi, Naohisa| Tsuchie, Hiroyuki| Kasukawa, Yuji| Kawaragi, Takashi| Nagahata, Itsuki| Suzuki, Masazumi| Yoshikawa, Takayuki| Abe, Toshiki| Shimada, Yoichi| |
| 抄録 | We report a case of atypical femoral fracture achieving early fracture union with combination therapy comprising contralateral nail and immediate teriparatide injection. Fracture union of atypical fractures is often delayed due to bowing deformity and bone metabolic disorders. Combination treatment that takes both problems into consideration represents a useful treatment option for atypical femoral fracture. |
| キーワード | atypical femoral fracture bowing deformity intramedullary nail teriparatide cephalomedullary screw |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 333 |
| 終了ページ | 338 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790365 |
| Web of Science KeyUT | 000823568300013 |
| JaLCDOI | 10.18926/AMO/63740 |
|---|---|
| フルテキストURL | 76_3_307.pdf |
| 著者 | Sugiura, Satoshi| Kitamura, Yoshihisa| Izushi, Yasuhisa| Ushio, Soichiro| Sendo, Toshiaki| |
| 抄録 | In recent years, medical staff including physicians and nurses have been participating in home health care, reflecting the needs of an aging society in Japan. Pharmacists are also asked to work on home health care teams to ensure the medical safety of patients. It currently remains unclear whether direct communication, i.e. a meeting, between home-visiting physicians and pharmacists contributes to the proper use of medications and continuous medical care. We retrospectively analyzed the medication management guidance records of home-visited patients who received their first home visit between April 2014 and March 2017. We collected data on pharmacist inquiries, the duration of visits, and details from a meeting between home-visiting physicians and pharmacists. Thirty-five patients were included. At the first visit, the inquiry rate by pharmacists was 65.7%. The prescription question rate was significantly lower in patients with a meeting than in those without (p=0.033). The average duration of visits was significantly shorter for home-visited patients whose health care providers had a meeting (p=0.007). These results suggest that pharmacists who held a meeting with the home-visiting physician before the first patient visit were able to resolve drug-related issues earlier, which increased the work efficiency of home-visiting pharmacists. |
| キーワード | home visit pharmacist meeting inquiry home health care |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 307 |
| 終了ページ | 315 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790361 |
| Web of Science KeyUT | 000823568300001 |
| JaLCDOI | 10.18926/AMO/63738 |
|---|---|
| フルテキストURL | 76_3_291.pdf |
| 著者 | Miyake, Yoshiaki| Mitani, Shigeru| Namba, Yoshifumi| Umehara, Norifumi| Kawamoto, Toyohiro| Furuichi, Shuro| |
| 抄録 | Total hip arthroplasty (THA) provides relief from hip pain and improves hip function. However, periprosthetic joint infection (PJI) remains an area of concern. We examined the detection rate of bacteria from surgical fields in wound closure, along with the relationship between bacterial detection rate and type of antiseptic, surgery time, and surgeon experience for 500 patients who underwent THA at our department. The mean age at surgery was 64.3 (± 27.3) years. The bacterial detection rate was 4.6%. None of the cases revealed PJI. No significant association between the detection rate and type of antiseptic used or surgery time was observed. However, for patients treated by surgeons with < 10 years of orthopedic experience, a detection rate of 7.3% was found, while a rate of 1.3% was observed for those treated by surgeons with ≥ 10 years of orthopedic experience. This finding indicated that orthopedic experience of less than 10 years was significantly associated with an increased bacterial detection rate (chi-square test, p=0.002). The detection rate was associated with surgeon experience but not with antiseptic type or surgery time. It is possible that intraoperative handling may increase the number of bacteria in surgical fields in wound closure. |
| キーワード | total hip arthroplasty bacterial contamination periprosthetic joint infection |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 291 |
| 終了ページ | 295 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790359 |
| Web of Science KeyUT | 000823568300008 |
| フルテキストURL | fulltext20220630-8.pdf |
|---|---|
| 著者 | Nishimura, Takeshi| Nojima, Tsuyoshi| Naito, Hiromichi| Ishihara, Satoshi| Nakayama, Shinichi| Nakao, Atsunori| |
| キーワード | JTDB Prehospital Emergency life-saving technician Trauma |
| 発行日 | 2022-06 |
| 出版物タイトル | The American Journal of Emergency Medicine |
| 巻 | 56巻 |
| 出版者 | Elsevier BV |
| 開始ページ | 218 |
| 終了ページ | 222 |
| ISSN | 0735-6757 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 The Authors. |
| 論文のバージョン | publisher |
| PubMed ID | 35447563 |
| DOI | 10.1016/j.ajem.2022.04.004 |
| Web of Science KeyUT | 000799775900035 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.ajem.2022.04.004 |
| JaLCDOI | 10.18926/AMO/63722 |
|---|---|
| フルテキストURL | 76_3_281.pdf |
| 著者 | Yu, Bo| Wang, Rui| Luo, Huikun| Yang, Di| Wang, Simo| Yu, Yaqiong| Okamura, Hirohiko| Qiu, Lihong| |
| 抄録 | Periodontal ligament (PDL) cells are critical for the bone remodeling process in periapical lesions since they can differentiate into osteoblasts and secrete osteoclastogenesis-promoting cytokines. Post-translational histone modifications including alterations of the methylation status of H3K27 are involved in cell differentiation and inflammatory reaction. The histone demethylase Jumonji domain-containing 3 (Jmjd3) specifically removes methylation of H3K27. We investigated whether Jmjd3 is involved in the osteogenic differentiation and secretion of PDL cells’ inflammatory factors. Jmjd3 expression in periapical lesions was examined by immunostaining. Using siRNA specific for Jmjd3 or the specific Jmjd3 inhibitor GSK-J4, we determined Jmjd3’s roles in osteogenic differentiation and cytokine production by real-time RT-PCR. The locations of Jmjd3 and NF-κB were analyzed by immunocytochemistry. Compared to healthy PDLs, the periapical lesion samples showed higher Jmjd3 expression. Treatment with GSK-J4 or Jmjd3 siRNA suppressed PDL cells’ osteogenic differentiation by suppressing the expressions of bone-related genes (Runx2, Osterix, and osteocalcin) and mineralization. Jmjd3 knockdown decreased the expressions of cytokines (TNF-α, IL-1β, and IL-6) induced by lipopolysaccharide extracted from Porphyromonas endodontalis (Pe-LPS). Pe-LPS induced the nuclear translocations of Jmjd3 and NF-κB; the latter was inhibited by GSK-J4 treatment. Jmjd3 appears to regulate PDL cells’ osteogenic differentiation and proinflammatory cytokine expressions. |
| キーワード | periapical lesions histone demethylase Jmjd3 periodontal ligament cell osteogenic differentiation proinflammatory cytokines |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 281 |
| 終了ページ | 290 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790358 |
| Web of Science KeyUT | 000823568300007 |
| JaLCDOI | 10.18926/AMO/63720 |
|---|---|
| フルテキストURL | 76_3_265.pdf |
| 著者 | Kosaki, Yoshinori| Naito, Hiromichi| Iida, Atsuyoshi| Ihoriya, Hiromi| Nojima, Tsuyoshi| Yamada, Taihei| Yamamoto, Hirotsugu| Nakamura, Shunsuke| Mandai, Yasuhiro| Nakao, Atsunori| |
| 抄録 | Basic life support (BLS) courses for laypersons, including cardiopulmonary resuscitation (CPR) training, is known to improve outcomes of out-of-hospital cardiac events. We asked medical students to provide BLS training for laypersons as a part of their emergency medicine education and evaluated the effects of training on the BLS skills of laypersons. We also used a questionnaire to determine whether the medical students who provided the BLS training were themselves more confident and motivated to perform BLS compared to students who did not provide BLS training. The proportions of laypersons who reported confidence in checking for a response, performing chest compressions, and automated external defibrillator (AED) use were significantly increased after the BLS training. The proportions of medical students who reported increased confidence/motivation in terms of understanding BLS, checking for a response, chest compression, use of AED, and willingness to perform BLS were significantly greater among medical students who provided BLS instructions compared to those who did not. BLS instruction by medical students was associated with an improvement in laypersons’ CPR accuracy and confidence in responding to cardiac arrest. The results indicate that medical students could gain understanding, confidence, and motivation in regard to their BLS skills by teaching BLS to laypersons. |
| キーワード | BLS medical education emergency medicine resuscitation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 265 |
| 終了ページ | 271 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790356 |
| Web of Science KeyUT | 000823568300005 |
| JaLCDOI | 10.18926/AMO/63719 |
|---|---|
| フルテキストURL | 76_3_255.pdf |
| 著者 | Nakatsuka, Kosuke| Matsuoka, Yoshikazu| Kurita, Masako| Wang, Ruilin| Tsuboi, Chika| Sue, Nobutaka| Kaku, Ryuji| Morimatsu, Hiroshi| |
| 抄録 | Mirror image pain (MIP) is a type of extraterritorial pain that results in contralateral pain or allodynia. Glutamate transporter-1 (GLT-1) is expressed in astrocytes and plays a role in maintaining low glutamate levels in the synaptic cleft. Previous studies have shown that GLT-1 dysfunction induces neuropathic pain. Our previous study revealed bilateral GLT-1 downregulation in the spinal cord of a spared nerve injury (SNI) rat. We hypothesized that spinal GLT-1 is involved in the mechanism of MIP. We also previously demonstrated noradrenergic GLT-1 regulation. Therefore, this study aimed to investigate the effect of an α1 adrenergic antagonist on the development of MIP. Rats were subjected to SNI. Changes in pain behavior and GLT-1 protein levels in the SNI rat spinal cords were then examined by intrathecal administration of the α1 adrenergic antagonist phentolamine, followed by von Frey test and western blotting. SNI resulted in the development of MIP and bilateral downregulation of GLT-1 protein in the rat spinal cord. Intrathecal phentolamine increased contralateral GLT-1 protein levels and partially ameliorated the 50% paw withdrawal threshold in the contralateral hind paw. Spinal GLT-1 upregulation by intrathecal phentolamine ameliorates MIP. GLT-1 plays a role in the development of MIPs. |
| キーワード | alpha adrenergic receptor glutamate transporter-1 mirror image pain neuropathic pain spared nerve injury |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-06 |
| 巻 | 76巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 255 |
| 終了ページ | 263 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 35790355 |
| Web of Science KeyUT | 000823568300004 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Minakuchi, Hajime| Fujisawa, Masanori| Abe, Yuka| Iida, Takashi| Oki, Kyosuke| Okura, Kazuo| Tanabe, Norimasa| Nishiyama, Akira| |
| キーワード | Sleep bruxism Management Systematic review Oral appliances Biofeedback therapy Cognitive-behavioral therapy Pharmacological therapy |
| 発行日 | 2022-11 |
| 出版物タイトル | Japanese Dental Science Review |
| 巻 | 58巻 |
| 出版者 | Elsevier Ltd. |
| 開始ページ | 124 |
| 終了ページ | 136 |
| ISSN | 1882-7616 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022Published by Elsevier Ltd on behalf of The Japanese Association for Dental Science. |
| 論文のバージョン | publisher |
| PubMed ID | 35356038 |
| DOI | 10.1016/j.jdsr.2022.02.004 |
| Web of Science KeyUT | 000806374300002 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.jdsr.2022.02.004 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Okada, Tomoaki| Miyoshi, Toru| Doi, Masayuki| Nosaka, Kazumasa| Tsushima, Ryu| Ugawa, Satoko| Takagi, Wataru| Sogo, Masahiro| Takahashi, Masahiko| Ito, Hiroshi| |
| キーワード | evolocumab pitavastatin lipoprotein(a) percutaneous coronary intervention hypolipidemic agents myocardial infarction |
| 発行日 | 2022-05-12 |
| 出版物タイトル | Journal Of Cardiovascular Development and Disease |
| 巻 | 9巻 |
| 号 | 5号 |
| 出版者 | MDPI |
| 開始ページ | 153 |
| ISSN | 2308-3425 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 35621864 |
| DOI | 10.3390/jcdd9050153 |
| Web of Science KeyUT | 000801748900001 |
| 関連URL | isVersionOf https://doi.org/10.3390/jcdd9050153 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yamamoto, Norio| Sukegawa, Shintaro| Watari, Takashi| |
| キーワード | medical malpractice claims litigation diagnostic error medical error system error machine learning prediction model |
| 発行日 | 2022-05-12 |
| 出版物タイトル | Healthcare |
| 巻 | 10巻 |
| 号 | 5号 |
| 出版者 | MDPI |
| 開始ページ | 892 |
| ISSN | 2227-9032 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 35628029 |
| DOI | 10.3390/healthcare10050892 |
| Web of Science KeyUT | 000801248000001 |
| 関連URL | isVersionOf https://doi.org/10.3390/healthcare10050892 |