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JaLCDOI 10.18926/AMO/55661
フルテキストURL 72_1_39.pdf
著者 Hosogi, Mika| Morizane, Yuki| Shiode, Yusuke| Doi, Shinichiro| Kumase, Fumiaki| Kimura, Shuhei| Hosokawa, Mio| Hirano, Masayuki| Toshima, Shinji| Takahashi, Kosuke| Fujiwara, Atsushi| Shiraga, Fumio|
抄録 To investigate the effectiveness of a treat-and-extend regimen (TAE) of intravitreal ranibizumab injections (IVR) for macular edema (ME) due to branch retinal vein occlusion (BRVO). We retrospectively examined 35 eyes of 35 patients with ME due to BRVO who underwent TAE for 1 year. Patients whose treatment interval extended to 12 weeks were switched to a pro re nata regimen (PRN; TAE to PRN group), while TAE was continued for patients whose treatment interval was less than 12 weeks (continued TAE group). Changes in best-corrected visual acuity (BCVA), central retinal thickness (CRT), and predictive factors for inclusion in the TAE to PRN group were analyzed. BCVA and CRT both improved significantly at 1 year compared with baseline (p<0.001). Sixteen eyes (45.7%) were included in the TAE to PRN group, while 19 eyes (54.3%) were included in the continued TAE group. BCVA in the TAE to PRN group was significantly better than that in the continued TAE group at 1 year (p=0.047). BCVA at baseline and macular BRVO were significant predictive factors for inclusion in the TAE to PRN group. TAE was effective for improving BCVA and CRT. The TAE to PRN group showed significantly better prognosis.
キーワード branch retinal vein occlusion macular edema anti-vascular endothelial growth factor ranibizumab treat-and-extend regimen
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-02
72巻
1号
出版者 Okayama University Medical School
開始ページ 39
終了ページ 45
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29463937
Web of Science KeyUT 000426542800006
NAID 120006398861
JaLCDOI 10.18926/AMO/55660
フルテキストURL 72_1_31.pdf
著者 Owari, Yutaka| Miyatake, Nobuyuki| Kataoka, Hiroaki|
抄録 Few studies examined the relationship between social participation, physical activity and psychological distress in elderly people. Here we examined these relationships in apparently healthy elderly people. After exclusion of subjects who dropped out or did not meet enrollment criteria, the data of 86 subjects (apparently healthy elderly embers at a college health club; 25 males, 61 females) from July 20 to September 10, 2016 were used. We evaluated each subject’s psychological distress using the K6 questionnaire, social participation by a self-completed questionnaire, and physical activity level by a triaxial accelerometer (7 consecutive days). The K6 scores were significantly correlated with social participation in the total series and the women. The K6 scores of the subjects who had engaged in social participation (1.847±2.231) were significantly lower (better) than those of the subjects who had not (6.714±5.014). Both exercise limitation and social participation were significant predictors of the K6 scores. Our findings indicate that psychological distress in apparently healthy elderly people is not associated with physical activity, but is associated with social participation. Our results demonstrate that in healthy elderly people, participating in a social activity can help improve psychological distress.
キーワード elderly people physical activity psychological distress social participation
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-02
72巻
1号
出版者 Okayama University Medical School
開始ページ 31
終了ページ 37
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29463936
JaLCDOI 10.18926/AMO/55659
フルテキストURL 72_1_23.pdf
著者 Fujiia, Masayoshi| Takata, Katsuyoshi| Chuang, Shih-Sung| Miyata-Takata, Tomoko| Ando, Midori| Sato, Yasuharu| Yoshino, Tadashi|
抄録 The gastrointestinal (GI) tract is the most frequently involved site of extranodal non-Hodgkin lymphomas, and diffuse large B-cell lymphoma (DLBCL) is the most common subtype occurring in the GI tract. TNFAIP3 (A20) genetic alterations were reported to be involved in DLBCL’s pathogenesis and a portion of GI-DLBCL cases harbor this alteration. However, the frequency and clinicopathological relations focusing on small and large intestinal DLBCL are unclear. Here, we examined A20 deletion and protein expression and analyzed the clinicopathological features of 52 cases of primary intestinal DLBCL. The most frequently involved site was the ileocecal region (75%), followed by small bowel (13.5%) and large intestine. Immunohistochemically, the ileocecal cases expressed BCL6 (p=0.027) and MUM1 (p=0.0001) significantly more frequently than the small intestinal cases. Six of 47 cases (13%) had A20 heterozygous deletion, whereas all 6 heterozygously deleted cases had detectable A20 protein expression. In summary, A20 abnormality was less prevalent among intestinal DLBCLs with some discordancy between gene deletion and protein expression. Although the A20 alteration status did not affect any clinicopathological characteristics in this series, further studies exploring alterations of A20 and other NF-κB components in primary intestinal DLBCL are needed.
キーワード primary intestinal diffuse large B-cell lymphoma cell of origin A20 TNFAIP3 heterozygous deletion
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-02
72巻
1号
出版者 Okayama University Medical School
開始ページ 23
終了ページ 30
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29463935
JaLCDOI 10.18926/AMO/55658
フルテキストURL 72_2_203.pdf
著者 Sonekatsu, Mayumi| Sonohata, Motoki| Kitajima, Masaru| Kawano, Shunsuke| Mawatari, Masaaki|
抄録 In patients with poliomyelitis, degenerative arthritis of the hip may be encountered in the paralytic or normal contralateral limb because of leg length discrepancy, pelvic obliquity, or severe deformities of the affected hip. Although total hip arthroplasty (THA) is one of the most common orthopedic procedures, there are few reports of THA in adult patients with residual poliomyelitis. From March 2001 to January 2011, 5 patients with residual poliomyelitis (6 hips) underwent THA using uncemented implants at our hospital. We retrospectively evaluated the Japanese Orthopedic Association (JOA) hip rating score, complications, and radiographs. All five patients’ follow-up information was available: 4.5 years minimum, 8.4 years average, range 4.5-15 years. Surgery was done at the same side of the paralytic limb in 2 hips and contralateral to the paralytic limb in four hips. All patients had pain relief and improvement in function; JOA hip rating score improved significantly from the mean of 45 preoperatively to 78 at the last follow-up (p=0.0313). There was no loosening or osteolysis in this series, and no cases of dislocation, infection or nerve palsy. These findings can contribute to decisions regarding treatment for arthritic hips in adults with residual poliomyelitis.
キーワード total hip arthroplasty poliomyelitis residual neuromuscular disease complication
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-02
72巻
1号
出版者 Okayama University Medical School
開始ページ 17
終了ページ 22
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29463934
Web of Science KeyUT 000426542800003
関連URL isReplacedBy http://doi.org/10.18926/AMO/55864
JaLCDOI 10.18926/AMO/55657
フルテキストURL 72_1_9.pdf
著者 Kataoka, Hiroaki| Miyatake, Nobuyuki| Murao, Satoshi| Tanaka, Satoshi|
抄録 Resistance training is effective against type 2 diabetes (T2DM), but the effect of resistance training on toe pinch force (TPF) is unknown. Here we investigated the effect of short-term toe resistance training on TPF in patients with T2DM, in a prospective, parallel-group, single-blind, randomized controlled trial. Twelve patients with T2DM who were hospitalized to improve glycemic control were enrolled. The patients were randomly allocated to the intervention (n=6) and control (n=6) groups. The intervention group performed traditional aerobic exercise and 4 newly developed toe-resistance training exercises. The control group performed aerobic exercise only. After 2 weeks of the exercise intervention program, we evaluated anthropometric parameters, clinical parameters, motor function, and muscle parameters in each patient. After the exercise intervention program, the TPF and toe muscle quality, isometric knee extension force, and knee muscle quality were significantly higher in the intervention group compared to the control group. Two weeks of toe-resistance training significantly increased the TPF in the T2DM patients. Toe resistance training is thus recommended in clinical practice for patients with T2DM.
キーワード randomized controlled trial type 2 diabetes mellitus toe resistance training toe pinch force toe muscle quality
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-02
72巻
1号
出版者 Okayama University Medical School
開始ページ 9
終了ページ 15
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29463933
JaLCDOI 10.18926/AMO/55656
フルテキストURL 72_1_1.pdf
著者 Saito, Yukihiro| Nakamura, Kazufumi| Ito, Hiroshi|
抄録 The number of permanent pacemaker implantations has been increasing due to the aging of populations worldwide and the increase in the numbers of patients with heart diseases. Commercially available mechanical pacemakers are very useful but still have some problems including short battery life, a risk of infection, the absence of physiological autonomic responsiveness, metal allergy, and electronic interference. A biological pacemaker may resolve these problems and regenerate the cardiac pacemaker. Cell-based therapy and gene therapy have been addressed with the goal of solving the challenges of biological pacemaker. However, the clinical application of a biological pacemaker has not yet been realized. Here we discuss the types of cells that can be used for a biological pacemaker and the problems that remain regarding the clinical applications of cell-based therapy.
キーワード cell therapy pluripotent stem cells cardiomyocytes biological pacemaker hyperpolarization activated cyclic nucleotide gated potassium channel 4
Amo Type Review
出版物タイトル Acta Medica Okayama
発行日 2018-02
72巻
1号
出版者 Okayama University Medical School
開始ページ 1
終了ページ 7
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 29463932
フルテキストURL PhysRevA_82_023624.pdf
著者 Mizushima, T.| Machida, K.|
備考 This is an article published by American Physical Society|
発行日 2010-08
出版物タイトル Physical Review A
82巻
2号
出版者 American Physical Society
開始ページ 023624
ISSN 1050-2947
NCID AA10764867
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 American Physical Society
論文のバージョン publisher
DOI 10.1103/PhysRevA.82.023624
Web of Science KeyUT 000281405500012
関連URL isVersionOf https://doi.org/10.1103/PhysRevA.82.023624
フルテキストURL srfa_107_contents_eng.pdf
著者 岡山大学農学部|
出版物タイトル 岡山大学農学部学術報告
発行日 2018-02-01
107巻
ISSN 2186-7755
言語 日本語
論文のバージョン publisher
フルテキストURL srfa_107_colophon.pdf
著者 岡山大学農学部|
出版物タイトル 岡山大学農学部学術報告
発行日 2018-02-01
107巻
ISSN 2186-7755
言語 日本語
論文のバージョン publisher
タイトル(別表記) The List of Published by Members of the Faculty From January to December 2017
フルテキストURL srfa_107_025_039.pdf
著者 岡山大学農学部|
出版物タイトル 岡山大学農学部学術報告
発行日 2018-02-01
107巻
開始ページ 25
終了ページ 39
ISSN 2186-7755
言語 日本語
論文のバージョン publisher
タイトル(別表記) Non-surgical Transfer Method of Elongating Bovine Conceptus
フルテキストURL srfa_107_019_024.pdf
著者 木村 康二|
抄録  The objectives of the present study were to establish a non-surgical transfer method for elongating bovine conceptuses and to combine this method with biopsy and sexing. Bovine conceptuses were recovered from donor cows on day 13-14 of the estrus cycle. In experiment 1, day 13 conceptuses were transferred to recipient cows using a standard day 7 embryo transfer (ET) method. The pregnancy rate of day 13 conceptus transfer (CT) is comparable to that of day 7 ET. In experiment 2, day 14 conceptuses were transferred using modified methods (balloon catheters or ET guns with modified sheaths). Using the standard ET method, no pregnancies were obtained;however, when balloon catheters or ET guns with modified sheaths were used, the pregnancy rates after CT were 48.0% and 44.8%, respectively. In experiment 3, day 14 conceptuses were biopsied without a micromanipulator, sexed using the loop-mediated isothermal amplification (LAMP) method, and transferred to recipient cows. The pregnancy rate of biopsied conceptuses was 46.2% and did not differ significantly from that of unbiopsied with conceptuses. Moreover, all pregnant cows transferred conceptuses following biopsy and sexing delivered calves with the expected sexes. These results suggested that the non-surgical bovine conceptus transfer (CT) method was comparable to day 7 ET, and that this technique enables biopsy and sexing without expensive equipment such as a micromanipulator or specialized skills.
キーワード conceptus biopsy
出版物タイトル 岡山大学農学部学術報告
発行日 2018-02-01
107巻
開始ページ 19
終了ページ 24
ISSN 2186-7755
言語 日本語
論文のバージョン publisher
タイトル(別表記) Virus-induced gene silencing in Prunus fruit tree species with the Apple latent spherical virus vector
フルテキストURL srfa_107_011_017.pdf
著者 河井 崇|
抄録 Virus-induced gene silencing (VIGS) has been used as a rapid and effective tool for functional analysis of genes in various plants, including woody fruit tree species. In this study, we attempted to develop a VIGS-based gene evaluation system for seven Prunus species, including apricot (P. armeniaca L.), sweet cherry (P. avium L.), almond [P. dulcis (Mill.) D. A. Webb.], peach (P. persica Batsch), Japanese apricot (P. mume Siebold & Zucc.), Japanese plum (P. salicina Lindl.), and European plum (P. domestica L.), with the Apple latent spherical virus (ALSV) vectors. ALSV vectors carrying part of the apricot PHYTOENE DESATURASE (PDS) gene sequence were amplified in Nicotiana benthamiana, and inoculated into the cotyledons of Prunus seedlings by particle bombardment. Typical PDS-silenced phenotypes, characterized by uniform discoloration of the upper leaves, were observed in sweet cherry and some cultivars of apricot and almond several weeks after inoculation. In contrast, attempted ALSV infections of Japanese apricot, Japanese plum, European plum, and the other cultivars of apricot and almond were unsuccessful. Furthermore, although the infection rate of ALSV in peach was high, severe viral infection symptoms were observed in the infected leaves. These results collectively suggested that the efficiency of ALSV infection and VIGS could vary depending on species and/or cultivar in Prunus. The possible use of the ALSV-mediated VIGS system for functional analysis of genes in Prunus is discussed.
キーワード gene evaluation system post-transcriptional gene silencing virus vector
出版物タイトル 岡山大学農学部学術報告
発行日 2018-02-01
107巻
開始ページ 11
終了ページ 17
ISSN 2186-7755
言語 日本語
論文のバージョン publisher
タイトル(別表記) Alzheimer’s disease : Relationship between the Alzheimer’s disease and human microbiome
フルテキストURL srfa_107_005_010.pdf
著者 藤井 祐介| 森田 英利|
抄録 Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by memory and language disorder. The accumulation of senile plaques called β-amyloid and neurofibrillary tangles involving protein tau in the brains of AD patients have been considered as two hallmarks of AD. In AD, it is reported that accumulation of β-amyloid may be observed 25 years before onset, supporting early diagnosis and treatment by brain image analysis, because several techniques have recently been developed to detect β-amyloid and tau protein in brains of persons diagnosed with AD. AD patients are usually suffering from other diseases such as diabetes or periodontal disease, and there is accumulating data to show that these diseases associate with the human microbiome, such as gut and oral microbiota. In this report, the relation ship between AD and the human microbiome is reviewed.
出版物タイトル 岡山大学農学部学術報告
発行日 2018-02-01
107巻
開始ページ 5
終了ページ 10
ISSN 2186-7755
言語 日本語
論文のバージョン publisher
タイトル(別表記) Effects of Olibanum and Tea-tree, used in Aromatherapy today, on the Body and Mind
フルテキストURL srfa_107_001_003.pdf
著者 浅田 昌古| 酒井 貴志| 清田 洋正|
抄録 Olibanum (frankincense), used as a religious offering, has been one of the most valuable and respected substances since ancient times. Tea-tree, with a long history as a folk medicine for Australian aborigines, has been used in modern aromatherapy since the late 1970’s. In this paper, comparisons of olibanum and tea-tree in aromatherapy and their effects on the body and mind are discussed.
キーワード flavor and fragrance frankincense aromatherapy monoterpenoids
出版物タイトル 岡山大学農学部学術報告
発行日 2018-02-01
107巻
開始ページ 1
終了ページ 3
ISSN 2186-7755
言語 日本語
論文のバージョン publisher
フルテキストURL srfa_107_contents.pdf
著者 岡山大学農学部|
出版物タイトル 岡山大学農学部学術報告
発行日 2018-02-01
107巻
ISSN 2186-7755
言語 日本語
論文のバージョン publisher
フルテキストURL srfa_107_cover.pdf
著者 岡山大学農学部|
出版物タイトル 岡山大学農学部学術報告
発行日 2018-02-01
107巻
ISSN 2186-7755
言語 日本語
論文のバージョン publisher
フルテキストURL PhysRevA_84_011607.pdf
著者 Kawakami, Takuto| Mizushima, Takeshi| Machida, Kazushige|
備考 This is an article published by American Physical Society|
発行日 2011-07
出版物タイトル Physical Review A
84巻
1号
出版者 American Physical Society
開始ページ 011607
ISSN 2469-9926
NCID AA10764867
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 American Physical Society
論文のバージョン publisher
DOI 10.1103/PhysRevA.84.011607
Web of Science KeyUT 000293126500002
関連URL isVersionOf https://doi.org/10.1103/PhysRevA.84.011607
フルテキストURL PhysRevA_86_013812.pdf
著者 Yoshimura, Motohiko| Sasao, N.| Tanaka, M.|
備考 This is an article published by American Physical Society|
発行日 2012-07
出版物タイトル Physical Review A
86巻
1号
出版者 American Physical Society
開始ページ 013812
ISSN 1050-2947
NCID AA10764867
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 American Physical Society
論文のバージョン publisher
DOI 10.1103/PhysRevA.86.013812
Web of Science KeyUT 000306188200009
関連URL isVersionOf https://doi.org/10.1103/PhysRevA.86.013812
フルテキストURL PhysRevA_96_063827.pdf
著者 Hara, Hideaki| Miyamoto, Yuki| Hiraki, Takahiro| Masuda, Takahiko| Sasao, Noboru| Uetake, Satoshi| Yoshimi, Akihiro| Yoshimura, Koji| Yoshimura, Motohiko|
備考 This is an article published by American Physical Society|
発行日 2017-12
出版物タイトル Physical Review A
96巻
6号
出版者 American Physical Society
開始ページ 063827
ISSN 2469-9926
NCID AA10764867
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 American Physical Society
論文のバージョン publisher
DOI 10.1103/PhysRevA.96.063827
Web of Science KeyUT 000418297700009
関連URL isVersionOf https://doi.org/10.1103/PhysRevA.96.063827
フルテキストURL PhysRevB_93_104508.pdf
著者 Zheng, Lu| Miao, Xiao| Sakai, Yusuke| Goto, Hidenori| Uesugi, Eri| Eguchi, Ritsuko| Nishiyama, Saki| Sugimoto, Kunihisa| Fujiwara, Akihiko| Kubozono, Yoshihiro|
備考 This is an article published by American Physical Society|
発行日 2016-03
出版物タイトル Physical Review B
93巻
10号
出版者 American Physical Society
開始ページ 104508
ISSN 2469-9950
NCID AA11187113
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 American Physical Society
論文のバージョン publisher
DOI 10.1103/PhysRevB.93.104508
Web of Science KeyUT 000371732500002
関連URL isVersionOf https://doi.org/10.1103/PhysRevB.93.104508