
検索結果 471 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Miyaji, Mary| Kawano, Shinji| Furuta, Ryohei| Murakami, Emi| Ikeda, Shogo| Tsutsui, Kimiko M.| Tsutsui, Ken| |
| 発行日 | 2023-08-04 |
| 出版物タイトル | PLoS ONE |
| 巻 | 18巻 |
| 号 | 8号 |
| 出版者 | Public Library of Science |
| 開始ページ | e0289599 |
| ISSN | 1932-6203 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Miyaji et al. |
| 論文のバージョン | publisher |
| PubMed ID | 37540655 |
| DOI | 10.1371/journal.pone.0289599 |
| Web of Science KeyUT | 001043329800051 |
| 関連URL | isVersionOf https://doi.org/10.1371/journal.pone.0289599 |
| フルテキストURL | K003036.pdf |
|---|---|
| 著者 | 村上 要介| |
| 発行日 | 2005-09-30 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第3036号 |
| 学位授与年月日 | 2005-09-30 |
| 学位・専攻分野 | 博士(理学) |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| フルテキストURL | O004075.pdf |
|---|---|
| 著者 | 村上 正明| |
| 発行日 | 2005-12-31 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 乙第4075号 |
| 学位授与年月日 | 2005-12-31 |
| 学位・専攻分野 | 博士(医学) |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| JaLCDOI | 10.18926/AMO/65749 |
|---|---|
| フルテキストURL | 77_4_387.pdf |
| 著者 | Kataoka, Takahiro| Habu, Hiroshi| Tanaka, Ayumi| Naoe, Shota| Murakami, Kaito| Fujimoto, Yuki| Yukimine, Ryohei| Takao, Soshi| Mitsunobu, Fumihiro| Yorifuji, Takashi| Yamaoka, Kiyonori| |
| 抄録 | No epidemiological studies have examined the health effects of daily bathing in radon hot springs. In this cross-sectional study, we investigated the associations between radon hot spring bathing and health conditions. The target population was 5,250 adults ≥ 20 years old in the town of Misasa, Japan. We collected information about the participants’ bathing habits and alleviation of a variety of disease symptoms, and their self-rated health (SRH). Unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CI) were calculated. In both the adjusted and unadjusted models of hypertension, significant associations between the > 1×/week hot spring bathing and the alleviation of hypertension symptoms were observed compared to the group whose hot spring bathing was <1×/week: adjusted model, OR 5.40 (95%CI: 1.98-14.74); unadjusted model, 3.67 (1.50-8.99) and for gastroenteritis: adjusted model, 9.18 (1.15-72.96); unadjusted model, 7.62 (1.59-36.49). Compared to the no-bathing group, higher SRH was significantly associated with both bathing < 1×/week: unadjusted model, 2.27 (1.53-3.37) and > 1×/week: adjusted model, 1.91 (1.15-3.19). These findings suggest that bathing in radon hot springs is associated with higher SRH and the alleviation of hypertension and gastroenteritis. |
| キーワード | radon hot spring bathing habit self-rated health cross-section study |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-08 |
| 巻 | 77巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 387 |
| 終了ページ | 394 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37635139 |
| Web of Science KeyUT | 001163659800003 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Sukegawa, Shintaro| Ono, Sawako| Tanaka, Futa| Inoue, Yuta| Hara, Takeshi| Yoshii, Kazumasa| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Katsumitsu, Shimada| Nakai, Fumi| Nakai, Yasuhiro| Miyazaki, Ryo| Murakami, Satoshi| Nagatsuka, Hitoshi| Miyake, Minoru| |
| 備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-38343-y| |
| 発行日 | 2023-07-19 |
| 出版物タイトル | Scientific Reports |
| 巻 | 13巻 |
| 号 | 1号 |
| 出版者 | Nature Portfolio |
| 開始ページ | 11676 |
| ISSN | 2045-2322 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023 |
| 論文のバージョン | publisher |
| PubMed ID | 37468501 |
| DOI | 10.1038/s41598-023-38343-y |
| Web of Science KeyUT | 001033545700013 |
| 関連URL | isVersionOf https://doi.org/10.1038/s41598-023-38343-y |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Nakamura, Kayo| Murakami, Etsuko| Kishino, Daizo| Mashimo, Shuko| Kurioka, Yusuke| Shibata, Yusaku| Taniguchi, Arihiko| Higo, Hisao| Hiramatsu, Yasushi| Maeda, Yoshinobu| Miyahara, Nobuaki| |
| キーワード | Mycobacterium shinjukuense Nontuberculous mycobacterium Mycobacterium tuberculosis Clarithromycin |
| 発行日 | 2023-07-08 |
| 出版物タイトル | Respiratory Medicine Case Reports |
| 巻 | 45巻 |
| 出版者 | Elsevier |
| 開始ページ | 101894 |
| ISSN | 2213-0071 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 37485238 |
| DOI | 10.1016/j.rmcr.2023.101894 |
| Web of Science KeyUT | 001040257700001 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.rmcr.2023.101894 |
| フルテキストURL | fulltext20230530-02-2.pdf |
|---|---|
| 著者 | Tanaka, Katsunori| Sugiyama, Mitsuhiro| Shigita, Gentaro| Murakami, Ryoma| Duong, Thanh-Thuy| Aierken, Yasheng| Artemyeva, Anna M| Mamypbelov, Zharas| Ishikawa, Ryuji| Nishida, Hidetaka| Kato, Kenji| |
| キーワード | Central Asia Cucumis melo diversity genetic resources on-farm conservation |
| 発行日 | 2023 |
| 出版物タイトル | Breeding Science |
| 巻 | 73巻 |
| 号 | 2号 |
| 出版者 | Japanese Society of Breeding |
| 開始ページ | 219 |
| 終了ページ | 229 |
| ISSN | 1344-7610 |
| NCID | AA11353132 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Japanese Society of Breeding. |
| 論文のバージョン | publisher |
| DOI | 10.1270/jsbbs.22030 |
| Web of Science KeyUT | 000982572900001 |
| 関連URL | isVersionOf https://doi.org/10.1270/jsbbs.22030 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Naoe, Shota| Fujimoto, Yuki| Murakami, Kaito| Yukimine, Ryohei| Tanaka, Ayumi| Yamaoka, Kiyonori| Kataoka, Takahiro| |
| キーワード | low-dose/high-dose-rate irradiation forced swim test alcohol oxidative stress antioxidants |
| 発行日 | 2023-05-17 |
| 出版物タイトル | Journal of Radiation Research |
| 巻 | 64巻 |
| 号 | 4号 |
| 出版者 | Oxford University Press |
| 開始ページ | 635 |
| 終了ページ | 643 |
| ISSN | 0449-3060 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s) 2023. |
| 論文のバージョン | publisher |
| PubMed ID | 37205845 |
| DOI | 10.1093/jrr/rrad030 |
| Web of Science KeyUT | 000990840900001 |
| 関連URL | isVersionOf https://doi.org/10.1093/jrr/rrad030 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yagisawa, Takuya| Uchiyama, Jumpei| Takemura-Uchiyama, Iyo| Ando, Shun| Ichii, Osamu| Murakami, Hironobu| Matsushita, Osamu| Katagiri, Seiji| |
| キーワード | dairy cows low fertility uterine microbiota microbial diversity bacterial association |
| 発行日 | 2023-04-26 |
| 出版物タイトル | Microbiology Spectrum |
| 巻 | 11巻 |
| 号 | 3号 |
| 出版者 | American Society for Microbiology |
| 開始ページ | e04764-22 |
| ISSN | 2165-0497 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2023 Yagisawa et al. |
| 論文のバージョン | publisher |
| PubMed ID | 37098918 |
| DOI | 10.1128/spectrum.04764-22 |
| Web of Science KeyUT | 000975042800001 |
| 関連URL | isVersionOf https://doi.org/10.1128/spectrum.04764-22 |
| JaLCDOI | 10.18926/AMO/65146 |
|---|---|
| フルテキストURL | 77_2_169.pdf |
| 著者 | Inoue, Kanae| Fujita, Rio| Nagahara, Takatoshi| Murakami, Shiho| Nagai, Yuta| Moriwake, Rina| Miyake, Nozomi| Wakuta, Akiko| Kariyama, Kazuya| Nishimura, Mamoru| Nouso, Kazuhiro| |
| 抄録 | Alcoholic liver disease is a risk factor for non-virus-related hepatocellular carcinoma (HCC), which is increasing in prevalence. This study aimed to identify the factors for recovery from alcoholic liver failure. Sixty-two consecutive patients hospitalized for alcoholic liver failure at Okayama City Hospital were enrolled. The characteristics of patients who survived to the 1-month follow-up and whose liver function improved to Child–Pugh A at 3 months (CPA3) and 12 months (CPA12) were compared with the rest of the patients. The survivors at 1 month (50 patients) were significantly younger than the deceased patients and had better liver and renal function with higher levels of γ-glutamyl transferase (GGT). The same factors, except renal function, were correlated with achieving CPA3. High AST, ALT, and GGT levels as well as short spleen length, total abstinence, and good Child–Pugh scores at admission were identified as factors for achieving CPA12. The extent of alcohol intake before admission was not identified as a risk factor in any analysis. In conclusion, baseline liver function is crucial for survival and achieving CPA3, whereas high transaminase and γ-GTP levels, the absence of splenomegaly, and total abstinence are significant factors for achieving CPA12. |
| キーワード | alcoholic liver failure risk factors recovery |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-04 |
| 巻 | 77巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 169 |
| 終了ページ | 177 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 37094954 |
| Web of Science KeyUT | 000982503800006 |
| JaLCDOI | 10.18926/AMO/64355 |
|---|---|
| フルテキストURL | 77_1_1.pdf |
| 著者 | Nahar, Lutfun| Hagiya, Hideharu| Nada, Takahiro| Iio, Koji| Gotoh, Kazuyoshi| Matsushita, Osamu| Otsuka, Fumio| |
| 抄録 | Inducible resistance to the macrolide, lincosamide, and streptogramin B (iMLSB) antibiotic family is a latent mechanism for antimicrobial resistance in Staphylococcus aureus. We here investigated the frequency and genotypic profiles of iMLSB resistance in clindamycin (CLDM)-susceptible S. aureus isolated in Okayama University Hospital from June 2020 to June 2021. We phenotypically screened the iMLSB resistance via D-zone test and performed PCR testing for the erythromycin ribosomal methylase (erm) genes: ermA and ermC. Among 432 CLDM-susceptible S. aureus isolates, 138 (31.9%) exhibited an iMLSB-resistance phenotype, with methicillinresistant S. aureus isolates (MRSA; 61 isolates: 58.6%) exhibiting higher positivity than methicillin-sensitive S. aureus isolates (MSSA; 77 isolates: 23.5%) (p<0.001). Male patients had a higher frequency of iMLSB resistance than females (OR [95%CI]: 1.8 [1.2-2.8]; p=0.007). Genotypically, ermA predominated in both MSSA (70.1%) and MRSA (86.9%) compared to ermC (14.3% in MSSA and 11.5% in MRSA). A single strain of MRSA possessed both ermA and ermC, while 12 (15.6%) MSSA isolates were negative for both ermA and ermC, suggesting the presence of other genetic mechanisms. Collectively, these results show that approximately 33% of CLDM-susceptible S. aureus isolates at our university hospital exhibited iMLSB resistance, predominantly caused by ermA in both MSSA and MRSA. |
| キーワード | antimicrobial resistance clindamycin erm D-zone test inducible MLSB |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2023-02 |
| 巻 | 77巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 1 |
| 終了ページ | 9 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36849140 |
| Web of Science KeyUT | 000953663800001 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Murakami, Hiroyuki| Matsuoka, Ken-Ichi| Asano, Takeru| Moriyama, Takashi| Matsumura, Akifumi| Fujiwara, Hideaki| Asada, Noboru| Ennishi, Daisuke| Nishimori, Hisakazu| Fujii, Keiko| Fujii, Nobuharu| Toji, Tomohiro| Yoshino, Tadashi| Maeda, Yoshinobu| |
| キーワード | Refractory acute myeloid leukemia Transplant B-cell lymphoma-2 Azacitidine Venetoclax |
| 発行日 | 2022-11-08 |
| 出版物タイトル | Case Reports In Oncology |
| 巻 | 15巻 |
| 号 | 3号 |
| 出版者 | Karger |
| 開始ページ | 974 |
| 終了ページ | 979 |
| ISSN | 1662-6575 |
| NCID | AA12780955 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 36636684 |
| DOI | 10.1159/000526697 |
| Web of Science KeyUT | 000905485600025 |
| 関連URL | isVersionOf https://doi.org/10.1159/000526697 |
| JaLCDOI | 10.18926/AMO/64126 |
|---|---|
| フルテキストURL | 76_6_743.pdf |
| 著者 | Tanaka, Masato| Suthar, Hardik| Desai, Dhvanit| Yamauchi, Taro| Arataki, Shinya| Fujiwara, Yoshihiro| Uotani, Koji| Oda, Yoshiaki| Misawa, Haruo| |
| 抄録 | We describe a floating technique via a posterolateral approach with intraoperative O-arm navigation to facilitate decompression of the spinal cord in thoracic myelopathy due to severe ossification of the posterior longitudinal ligament (OPLL). A 62-year-old man with myelopathy due to thoracic OPLL had left-leg muscle weakness, urinary disturbance, and spastic gait. Bilateral leg pain and gait disturbance had persisted for 2 years. He was successfully treated by the posterolateral OPLL floating procedure and posterior pedicle fixation under O-arm navigation. At a 2-year follow-up, manual muscle testing results and sensory function of the left leg had recovered fully. His cervical Japanese Orthopedic Association score had improved from 5/12 to 11/12. The novel intraoperative O-arm navigation-guided posterolateral floating procedure for thoracic OPLL is effective for achieving precise decompression and strong fixation with a posterior approach only and can provide an excellent result for severe thoracic OPLL without the risk of adverse events from intraoperative radiation. |
| キーワード | ossification of the posterior longitudinal ligament floating method navigation surgery C-arm free |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 743 |
| 終了ページ | 748 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549778 |
| Web of Science KeyUT | 000905195100016 |
| JaLCDOI | 10.18926/AMO/64121 |
|---|---|
| フルテキストURL | 76_6_705.pdf |
| 著者 | Higashikawa, Toshihiro| Ito, Tomohiko| Mizuno, Takurou| Ishigami, Keiichiro| Kuroki, Kengo| Maekawa, Naoto| Usuda, Daisuke| Izumida, Toshihide| Yamada, Shinya| Sangen, Ryusho| Hamada, Kazu| Kiyosawa, Jun| Saito, Atsushi| Iguchi, Masaharu| Kasamaki, Yuji| Nakahashi, Takeshi| Fukuda, Akihiro| Saito, Hitoshi| Kanda, Tsugiyasu| Okuro, Masashi| |
| 抄録 | The sodium glucose transporter 2 (SGLT2) inhibitor tofogliflozin is a glucose-lowering drug that causes the excretion of surplus glucose by inhibiting SGLT2. Because of tofogliflozin’s osmotic diuresis mechanism, patients’ serum electrolytes, body fluid levels, and cardiac function must be monitored. We retrospectively analyzed the cases of 64 elderly Japanese patients with type 2 diabetes mellitus (T2DM) who received tofogliflozin for 3 months. Their HbA1c, serum electrolytes (sodium, potassium, chloride), hematocrit, brain natriuretic peptide (cardiac volume load marker) and renin and aldosterone (RAA; an index of regulatory hormones involved in body fluid retention) were continuously monitored during the investigation period. Renal function and cardiac function (by echocardiography) were assessed throughout the period. HbA1c significantly decreased (β1=−0.341, p<0.0001, linear regression analysis [LRA]). Most of the hormonal, electrolyte, and physiological parameters were maintained throughout the study period. In these circumstances, E/e’ tended to decrease (β1=−0.382, p=0.13, LRA). Compared to the baseline, E/e’ was significantly decreased at 1 and 3 months (p<0.01, p<0.05). In the higher E/e’ group (E/e’≥10, n=34), E/e’ decreased significantly (β1=−0.63, p<0.05, LRA). ΔE/e’ was correlated with body-weight change during treatment (r=0.64, p<0.01). The 3-month tofogliflozin treatment improved glycemic control and diastolic function represented by E/e’ in T2DM patients, without affecting serum electrolytes, renal function, or RAA. No negative impacts on the patients were observed. Three-month tofogliflozin treatment lowered glucose and improved cardiac diastolic function. |
| キーワード | tofogliflozin SGLT2 inhibitor elderly patient HbA1c cardiac diastolic function |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 705 |
| 終了ページ | 713 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549773 |
| Web of Science KeyUT | 000905195100011 |
| JaLCDOI | 10.18926/AMO/64120 |
|---|---|
| フルテキストURL | 76_6_695.pdf |
| 著者 | Onishi, Hideki| Nouso, Kazuhiro| Takaki, Akinobu| Oyama, Atsushi| Adachi, Takuya| Wada, Nozomu| Takeuchi, Yasuto| Shiraha, Hidenori| Okada, Hiroyuki| |
| 抄録 | This study sought to identify factors that are predictive of a therapeutic response to hepatic arterial infusion chemotherapy (HAIC) by focusing on the number of prior transcatheter arterial chemoembolization (TACE) sessions. To determine the parameters predicting a good response to HAIC, we retrospectively analyzed 170 patients with hepatocellular carcinoma (HCC) who received HAIC regimens comprising low-dose cisplatin combined with 5-fluorouracil (LFP) or cisplatin (CDDP) for the first time. In both the LFP and CDDP regimens, the response rates were significantly lower in patients with three or more prior TACE sessions than in those with two or fewer prior TACE sessions (LFP 57% versus 28%; p=0.01, CDDP 27% versus 6%; p=0.01). Multivariable logistic regression analysis revealed that the number of prior TACE sessions (≥ 3) was significantly associated with non-responder status (odds ratio 4.17, 95% Confidence Interval (CI) 1.76-9.86) in addition to the HAIC regimen. Multivariable analysis using the Cox proportional hazards model revealed that a larger number of prior TACE sessions (≥ 3) was a significant risk factor for survival (hazard ratio 1.60, 95% CI 1.12-2.29) in addition to Child-Pugh class, serum alpha-fetoprotein concentration, and maximum diameter of HCC. HCC patients who receive fewer prior TACE sessions (≤ 2) were found to be better responders to HAIC. |
| キーワード | hepatic arterial infusion chemotherapy hepatocellular carcinoma refractory transcatheter arterial chemoembolization |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 695 |
| 終了ページ | 703 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549772 |
| Web of Science KeyUT | 000905195100010 |
| JaLCDOI | 10.18926/AMO/64118 |
|---|---|
| フルテキストURL | 76_6_679.pdf |
| 著者 | Asagi, Akinori| Sakaguchi, Chihiro| Nadano, Seijin| Nishina, Tomohiro| Hamamoto, Yasushi| Kataoka, Masaaki| Yamashita, Natsumi| Tanimizu, Masahito| Hyodo, Ichinosuke| |
| 抄録 | Chemotherapy is insufficient to treat macroscopic vascular invasion (MVI) of hepatocellular carcinoma (HCC). We retrospectively investigated the treatment outcomes of patients who underwent three-dimensional conformal radiotherapy (3D-CRT) for HCC MVI and analyzed prognostic factors by multivariate analysis using a Cox proportional hazard model. Sixty-five patients were studied. MVI sites were the portal vein (n=48 patients), portal and hepatic veins (n=8), and hepatic vein (n=9). The median irradiation dose was 50 Gy. The median survival time (MST) was 7.5 months. Performance status 2 or 3, modified albumin-bilirubin grade 2b or 3, and massive/diffuse type were poor prognostic factors. Nineteen patients (29%) with a treatment effect of 3 or 4 (≥ 50% of tumor necrosis or regression) at the irradiation sites according to the Response Evaluation Criteria in Cancer of the Liver showed longer survival than those with an effect of 1 or 2 (MST 18.7 vs. 5.9 months, p<0.001). No treatment-related death occurred. The hepatic function reserve was preserved in more than 70% of patients. 3D-CRT controlled HCC MVI safely and was suggested to be a good treatment option. |
| キーワード | hepatocellular carcinoma macroscopic vascular invasion portal vein tumor thrombosis hepatic vein tumor thrombosis three-dimensional conformal radiotherapy |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-12 |
| 巻 | 76巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 679 |
| 終了ページ | 688 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36549770 |
| Web of Science KeyUT | 000905195100008 |
| フルテキストURL | K0006685_abstract_review.pdf K0006685_summary.pdf |
|---|---|
| 著者 | 黒岡 直子| |
| 発行日 | 2022-09-22 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第6685号 |
| 学位授与年月日 | 2022-09-22 |
| 学位・専攻分野 | 博士(医学) |
| 授与大学 | 岡山大学 |
| 言語 | 英語 |
| JaLCDOI | 10.18926/AMO/64032 |
|---|---|
| フルテキストURL | 76_5_519.pdf |
| 著者 | Ishioka, Yoko| Yamashita, Hiroyuki| Hamaguchi, Kinya| Kuwahara, Yoshitaka| Nakamura, Kaoru| Nakatsuka, Mikiya| |
| 抄録 | To examine the outcome of gestational blood pressure and birth weight in women with normal pre-pregnancy BMI (18.5-25 kg/m2) who are at the lower and upper limits of this range, i.e., slightly underweight or slightly overweight. Overall, 2,038 Japanese women with low -risk who had delivered during January 2014–December 2016 were classified according to their pre-pregnancy BMI: underweight (< 18.5 kg/m2), slightly underweight (18.5≤BMI<21 kg/m2), normal (21≤BMI<23 kg/m2), slightly overweight (23≤BMI<25 kg/m2) and overweight (≤ 25 kg/m2). Their blood pressure during each trimester and birth weight was evaluated. The slightly overweight group showed a significantly higher blood pressure than the underweight and slightly underweight groups. Birth weight was lower in the slightly underweight than in the slightly overweight group (p<0.01). The incidence rate of “heavy for dates” (HFD) infants was significantly higher in the slightly overweight and overweight groups than in the other groups (p<0.05 and p<0.01, respectively). Weight gain of < 7 kg significantly increased the rate of “light for dates” (LFD) infants, while a weight gain of ≥13 kg significantly increased the rate of HFD infants (p<0.05 and p<0.01, respectively). Blood pressure during pregnancy was ssociated with pre-pregnancy BMI. The birth weight of infants of low-risk pregnant women is affected by both pre-pregnancy BMI and gestational weight gain. |
| キーワード | birth weight blood pressure normal body weight pregnancy pre-pregnancy BMI |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2022-10 |
| 巻 | 76巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 519 |
| 終了ページ | 526 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | Copyright Ⓒ 2022 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 36352798 |
| Web of Science KeyUT | 000884907100004 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Shigehiro, Tsukasa| Ueno, Maho| Kijihira, Mayumi| Takahashi, Ryotaro| Umemura, Chiho| Taha, Eman A.| Kurosaka, Chisaki| Asayama, Megumi| Murakami, Hiroshi| Satoh, Ayano| Nakamura, Yoshimasa| Futami, Junichiro| Masuda, Junko| |
| キーワード | breast cancer cells dendritic cells mesenteric lymph node myeloid-derived suppressor cells |
| 発行日 | 2022-09-20 |
| 出版物タイトル | International Journal Of Molecular Sciences |
| 巻 | 23巻 |
| 号 | 19号 |
| 出版者 | MDPI |
| 開始ページ | 11035 |
| ISSN | 1422-0067 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2022 by the authors. |
| 論文のバージョン | publisher |
| PubMed ID | 36232335 |
| DOI | 10.3390/ijms231911035 |
| Web of Science KeyUT | 000867767200001 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijms231911035 |
| フルテキストURL | fulltext20221017-1.pdf |
|---|---|
| 著者 | NEO, Sakurako| TAKEMURA-UCHIYAMA, Iyo| UCHIYAMA, Jumpei| MURAKAMI, Hironobu| SHIMA, Ayaka| KAYANUMA, Hideki| YOKOYAMA, Taiki| TAKAGI, Satoshi| KANAI, Eiichi| HISASUE, Masaharu| |
| キーワード | bile bile microbiota gallbladder hospitalized dog laboratory dog |
| 発行日 | 2022 |
| 出版物タイトル | Journal of Veterinary Medical Science |
| 巻 | 84巻 |
| 号 | 7号 |
| 出版者 | Japanese Society of Veterinary Science |
| 開始ページ | 1019 |
| 終了ページ | 1022 |
| ISSN | 0916-7250 |
| NCID | AA10796138 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | ©2022 The Japanese Society of Veterinary Science |
| 論文のバージョン | publisher |
| PubMed ID | 35650165 |
| DOI | 10.1292/jvms.22-0090 |
| Web of Science KeyUT | 000862768300020 |
| 関連URL | isVersionOf https://doi.org/10.1292/jvms.22-0090 |