| ID | 55863 |
| JaLCDOI | |
| フルテキストURL | |
| 著者 |
Takase, Ken
Department of Hematology, Kyushu Medical Center
Kada, Akiko
Clinical Research Center, Nagoya Medical Center
Iwasaki, Hiromi
Department of Hematology, Kyushu Medical Center
Yoshida, Isao
Department of Hematology and Oncology, Shikoku Cancer Center
Sawamura, Morio
Department of Clinical Research, Shibukawa Medical Center
Yoshio, Nobuyuki
Department of Hematology, Kanazawa Medical Center
Yoshida, Shinichiro
Department of Hematology, Nagasaki Medical Center
Iida, Hiroatsu
Department of Hematology, Nagoya Medical Center
Otsuka, Maki
Department of Hematology, Kagoshima Medical Center
Takafuta, Toshiro
Department of Clinical Research, Hiroshima-Nishi Medical Center
Ogata, Yuko
Department of Hematology, Nishibeppu National Hospital
Suehiro, Youko
Department of Hematology, Kyushu Cancer Center
Hirabayashi, Yukio
Department of Hematology, Matsumoto Medical Center, Matsumoto Hospital
Hishita, Terutoshi
Department of Hematology, Himeji Medical Center
Yoshida, Chikamasa
Department of Hematology, Minami-Okayama Medical Center
Ito, Takuo
Department of Hematology, Kure Medical Center
Hidaka, Michihiro
Department of Hematology, Kumamoto Medical Center
Tsutsumi, Ikuyo
Department of Hematology, Mito Medical Center
Saito, Akiko M.
Clinical Research Center, Nagoya Medical Center
Nagai, Hirokazu
Clinical Research Center, Nagoya Medical Center
|
| 抄録 | Standard therapy for idiopathic thrombocytopenic purpura (ITP) has not been established. We are conducting a multicenter, prospective trial to determine the efficacy and safety of short-term, high-dose dexamethasone therapy in ITP patients aged 18-80 years with platelet counts of <20, 000 /μL, or with <50, 000/ μL and bleeding symptoms. The primary endpoints of this trial are the proportion of responses (complete plus partial response) on day 180 (day 46+180) after the completion of the 46-day high-dose dexamethasone therapy. The results of this investigation of the effectiveness and safety of this regimen will be essential for the establishment of standard therapy for ITP.
|
| キーワード | idiopathic thrombocytopenic purpura
short-term
high-dose dexamethasone therapy
open-label
single-arm trial
|
| Amo Type | Clinical Study Protocol
|
| 出版物タイトル |
Acta Medica Okayama
|
| 発行日 | 2018-04
|
| 巻 | 72巻
|
| 号 | 2号
|
| 出版者 | Okayama University Medical School
|
| 開始ページ | 197
|
| 終了ページ | 201
|
| ISSN | 0386-300X
|
| NCID | AA00508441
|
| 資料タイプ |
学術雑誌論文
|
| 言語 |
英語
|
| 著作権者 | CopyrightⒸ 2018 by Okayama University Medical School
|
| 論文のバージョン | publisher
|
| 査読 |
有り
|
| PubMed ID |
