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著者 松村 拓大|
発行日 2007-03-23
出版物タイトル
資料タイプ 学位論文
JaLCDOI 10.18926/11763
タイトル(別表記) Immunological Abnormalities of Alveolar Macrophages in Patients with Sarcoidosis
フルテキストURL 001_039_050.pdf
著者 中田 安成|
抄録 Bronchoalveolar lavage is an invaluable means of accurately evaluating the inflammatory and immune processes in the human lung. Sarcoidosis is a multisystem disorder characterized by heightened immune processes at sites of disease activity. The lung is most commonly involved. Although granulomas are charactaristic pathologic features of this disease, a number of studies suggest that the initial lesion in the lung is a T-cell alveolitis (an accumulation of T-cellls in the lung). There are a lot of findings that show abnormal functions of alveolar macrophages obtained by bronchoalveolar lavage in the release of various monokines and arachidonic acid metabolites and metabolize oxygen. In this review, the abnormalities of alveolar macrophages implicated in pulmonary T-cell alveolitis and fibrosis are reviewed and their potential roles in the lungs are discussed.
キーワード sarcoidosis alveolar macrophage monokine metabolize oxygen arachidonic acid metabolite
出版物タイトル 岡山大学医療技術短期大学部紀要
発行日 1991-03-25
1巻
開始ページ 39
終了ページ 50
ISSN 0917-4494
言語 日本語
論文のバージョン publisher
NAID 120002313772
著者 菅田 裕士|
発行日 2007-03-23
出版物タイトル
資料タイプ 学位論文
JaLCDOI 10.18926/fest/11424
フルテキストURL 011_009_014.pdf
著者 Nishina Tomohiko| Tian Tian Chen| Fujita Kazutoshi| 石川 洋文|
抄録 The red fox (Vulpes vulepes) and the vole ( Clethrionomys refocanus) are principal hosts of Echinococcus multilocularis in Hokkaido, Japan. How protoscoleces increases in voles and the level of immunity in foxes remain unknown because of the lack of survey data, so that it is important to clarify these mecahnisms in order to develop control strategies against E. multilocularis. In this study, the growth of protoscoleces in the infected voles was approximated as the logistic curve, the level of immunity in the fox was assumed to depend on the experience of the infection with E. multilocularis, and the worm burden in the fox was assumed to be governed by the amount of protoscoleces in the vole. Our model showed that the population densities of the hosts and the level of immunity influenced the prevalence of the E. multilocularis.
キーワード Echinococcus multilocularis protoscoleces immunity worm burden stochastic model
出版物タイトル 岡山大学環境理工学部研究報告
発行日 2006-03-15
11巻
1号
開始ページ 9
終了ページ 14
ISSN 1341-9099
言語 英語
論文のバージョン publisher
NAID 120002314034
タイトル(別表記) Habenaria Mosaic Virus, A New Member of Potyvirus from Habenaria radiata Orchid
フルテキストURL 005_002_155_168.pdf
著者 井上 成信| 前田 孚憲| 光畑 興二| Gara I Wayan|
抄録 A potyvirus, isolated from Habenaria radiaata showing severe mosaic in the leaves named habenaria mosaic virus(HaMV). HaMV was transmitted by inoculation of sap to 6 of 41 species from 4 of 12 families. Systemic infection was cauded in Habenaria radiata, and local infection was produced in Chenopodium amaranticolor, C. quinoa, Spinacia olracea, Tetragonia expansa and Gomphrena globosa. HaMV was also transmitted by Myzus persicae in a non persistent manner, but not by Aphis gossypii. The virus has filamentous particles of c. 750×13nm. Sap from inoculated C. quinoa was infective after dilution to 10-5 but not 10-6, after 10 min at 60℃ but 65℃, or after 8-16 days at 20℃.In ultrathin sections of diseased leaves of Habenaria radiata and inoculated C. quinoa, virus particles were found to disperse in the cytoplasm. Cylindrical inclusions were present in the cytoplasm of infected cells, as pinwheels, scrolls or tubes. The inclusions observed in negatively stained crude sap preparations exhibited fine linear striation at about 5.2 nm intervals.The antiserum to HaMV produced by immunizing a rabbit had a titer of 1/512(precipitin test). HaMV showed distant serological relationships to potyvirus;alstroemeria mosaic virus, bean yellow mosaic virus, calanthe mild mosaic virus, clover yellow vein virus, dendrobium mosaic virus, freesia mosaic virus, turnip mosaic virus and watermelon mosaic virus 2.
キーワード Habenaria orchid Habenaria mosaic potyvirus Habenaria mosaic disease
出版物タイトル 岡山大学資源生物科学研究所報告
発行日 1998
5巻
2号
開始ページ 155
終了ページ 168
ISSN 0916-930X
言語 日本語
論文のバージョン publisher
タイトル(別表記) Ixia から分離された bean yellow mosaic virus
フルテキストURL 004_002_201_213.pdf
著者 辻 俊也| 前田 孚憲| 近藤 秀樹| 井上 成信|
抄録 A strain (Ixia-B) of bean yellow mosaic virus (BYMV) isolated from Ixia hybrida was characterized and compared with other isolates of BYMV and clover yellow vein virus (CYVV). Ixia-B was transmitted by aphids,Myzus presicae in a non-presistent manner and by sap-inoculation to 11 of 46 species in 5 of 10 families tested, and had a similar host range to that of some BYMV isolates, althrough some defferences were detected. Sap from diseased C. quinoa was infective after 10 min heating at 55℃ but not 60℃, after a dilution to 10-3 but not 10-4, and after 2 days but not 4 days at 20℃.The Virus particles were filamentous rods of about 13×820 nm. Ixia-B contaied a single protein species with a molecular weight of 34,000 and a single viral RNA with approximately 9,000 bases. In ultrahtin sections of leaf tissues from infected plants, the virus particles, cylindrical cytoplasmic inclusions and dense bodies were obsserved in the cytoplasm. The antiserum to Ixia-B produced by immunizing a rabbit had a titer of 1/512. A close serological relationship was revealed between Ixia-B and two strains of BYMV from crocus and gladiolus, but no relationship to clover yellow vein virus was found in agar gel diffusion tests. However,Ixia-B could be distinguished from two strains of BYMV by the formation of spurs among them in agar gel and by the differences in the patterns of peptide mapping of coat proteins. From these findings, Ixia-B was identified as a strain of BYMV.
キーワード Ixia hybrida Bean yellow mosaic virus Potyvirus
出版物タイトル 岡山大学資源生物科学研究所報告
発行日 1996
4巻
2号
開始ページ 201
終了ページ 213
ISSN 0916-930X
言語 英語
論文のバージョン publisher
NAID 120002313395
著者 松下 博和|
発行日 2006-12-31
出版物タイトル
資料タイプ 学位論文
著者 韓 松| 阿部 浅樹| 楢原 清顕| 近藤 康博|
発行日 2007-02
出版物タイトル 岡山大学農学部学術報告
96巻
1号
資料タイプ 紀要論文
著者 山﨑 理恵|
発行日 2004-03-25
出版物タイトル
資料タイプ 学位論文
著者 栗原 英見|
発行日 1992-03-28
出版物タイトル
資料タイプ 学位論文
著者 Umi Cahyaningsih|
発行日 1990-09-30
出版物タイトル
資料タイプ 学位論文
著者 矢田 義比古|
発行日 1985-06-30
出版物タイトル
資料タイプ 学位論文
著者 浜崎 啓介|
発行日 1977-03-31
出版物タイトル
資料タイプ 学位論文
著者 藤原 徹|
発行日 1982-03-31
出版物タイトル
資料タイプ 学位論文
著者 中川 和彦|
発行日 2001-03-25
出版物タイトル
資料タイプ 学位論文