検索結果 - 岡山大学学術成果リポジトリ

Evaluating the activity of N-89 as an oral antimalarial drug

フルテキストURL	fulltext.pdf
著者	Aly, Nagwa S. M.\| Matsumori, Hiroaki\| Dinh, Thi Quyen\| Sato, Akira\| Miyoshi, Shin-ichi\| Chang, Kyung-Soo\| Yu, Hak Sun\| Kubota, Takaaki\| Kurosaki, Yuji\| Cao, Duc Tuan\| Rashed, Gehan A.\| Kim, Hye-Sook\|
キーワード	New antimalarial candidate oral N-89 pharmacokinetics in vivo
発行日	2023-08-21
出版物タイトル	Parasites, Hosts and Diseases
巻	61巻
号	3号
出版者	Korean Society for Parasitology
開始ページ	282
終了ページ	291
ISSN	2982-5164
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2023 The Korean Society for Parasitology and Tropical Medicine
論文のバージョン	publisher
PubMed ID	37648233
DOI	10.3347/phd.23044
Web of Science KeyUT	001173327300006
関連URL	isVersionOf https://doi.org/10.3347/phd.23044

Calredoxin regulates the chloroplast NADPH-dependent thioredoxin reductase in Chlamydomonas reinhardtii

フルテキストURL	fulltext.pdf
著者	Zinzius, Karen\| Marchetti, Giulia Maria\| Fischer, Ronja\| Milrad, Yuval\| Oltmanns, Anne\| Kelterborn, Simon\| Yacoby, Iftach\| Hegemann, Peter\| Scholz, Martin\| Hippler, Michael\|
発行日	2023-07-20
出版物タイトル	Plant Physiology
巻	193巻
号	3号
出版者	Oxford University Press (OUP)
開始ページ	2122
終了ページ	2140
ISSN	0032-0889
NCID	AA00775335
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2023.
論文のバージョン	publisher
PubMed ID	37474113
DOI	10.1093/plphys/kiad426
Web of Science KeyUT	001091374700018
関連URL	isVersionOf https://doi.org/10.1093/plphys/kiad426

Clinical practice pattern of Pneumocystis pneumonia prophylaxis in systemic lupus erythematosus: a cross-sectional study from lupus registry of nationwide institutions (LUNA)

フルテキストURL	fulltext.pdf
著者	Onishi, Takahisa\| Sada, Ken-Ei\| Hayashi, Keigo\| Miyawaki, Yoshia\| Yoshimi, Ryusuke\| Shimojima, Yasuhiro\| Ohno, Shigeru\| Kajiyama, Hiroshi\| Ichinose, Kunihiro\| Sato, Shuzo\| Fujiwara, Michio\| Yajima, Nobuyuki\| Kida, Takashi\| Matsuo, Yusuke\| Nishimura, Keisuke\| Yamane, Takashi\|
キーワード	Systemic lupus erythematosus Pneumocystis jirovecii pneumonia Glucocorticoid Immunosuppressant Practice pattern
備考	The version of record of this article, first published in Arthritis Research & Therapy, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13075-024-03434-2\|
発行日	2024-11-12
出版物タイトル	Arthritis Research & Therapy
巻	26巻
号	1号
出版者	BMC
開始ページ	198
ISSN	1478-6354
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024.
論文のバージョン	publisher
PubMed ID	39533345
DOI	10.1186/s13075-024-03434-2
Web of Science KeyUT	001354057800004
関連URL	isVersionOf https://doi.org/10.1186/s13075-024-03434-2

Association between discontinuity of care and patient trust in the usual rheumatologist among patients with systemic lupus erythematosus: a cross-sectional study

フルテキストURL	fulltext.pdf
著者	Katayama, Yu\| Miyawaki, Yoshia\| Shidahara, Kenta\| Nawachi, Shoichi\| Asano, Yosuke\| Katsuyama, Eri\| Katsuyama, Takayuki\| Takano-Narazaki, Mariko\| Matsumoto, Yoshinori\| Oguro, Nao\| Yajima, Nobuyuki\| Ishikawa, Yuichi\| Sakurai, Natsuki\| Hidekawa, Chiharu\| Yoshimi, Ryusuke\| Ohno, Shigeru\| Ichikawa, Takanori\| Kishida, Dai\| Shimojima, Yasuhiro\| Sada, Ken-Ei\| Wada, Jun\| Thom, David H.\| Kurita, Noriaki\|
キーワード	Systemic lupus erythematosus Patient-physician relationship Outpatient visits Patient trust Discontinuity of care
備考	The version of record of this article, first published in Arthritis Research & Therapy, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13075-024-03428-0\|
発行日	2024-11-11
出版物タイトル	Arthritis Research & Therapy
巻	26巻
号	1号
出版者	BMC
開始ページ	195
ISSN	1478-6354
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024.
論文のバージョン	publisher
PubMed ID	39529181
DOI	10.1186/s13075-024-03428-0
Web of Science KeyUT	001352382300001
関連URL	isVersionOf https://doi.org/10.1186/s13075-024-03428-0

A randomized, open-label, clinical trial examined the effects of canagliflozin on albuminuria and eGFR decline using an individual pre-intervention eGFR slope

フルテキストURL	fulltext.pdf
著者	Miyamoto, Satoshi\| Heerspink, Hiddo J.L.\| de Zeeuw, Dick\| Sakamoto, Kota\| Yoshida, Michihiro\| Toyoda, Masao\| Suzuki, Daisuke\| Hatanaka, Takashi\| Nakamura, Tohru\| Kamei, Shinji\| Murao, Satoshi\| Hida, Kazuyuki\| Ando, Shinichiro\| Akai, Hiroaki\| Takahashi, Yasushi\| Kitada, Munehiro\| Sugano, Hisashi\| Nunoue, Tomokazu\| Nakamura, Akihiko\| Sasaki, Motofumi\| Nakatou, Tatsuaki\| Fujimoto, Kei\| Kawanami, Daiji\| Wada, Takashi\| Miyatake, Nobuyuki\| Kuramoto, Hiromi\| Shikata, Kenichi\|
キーワード	canagliflozin CANPIONE study chronic kidney disease microalbuminuria preintervention eGFR slope sodium-glucose cotransporter 2 inhibitor
発行日	2024-11
出版物タイトル	Kidney International
巻	106巻
号	5号
出版者	Elsevier BV
開始ページ	972
終了ページ	984
ISSN	0085-2538
NCID	AA00710996
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 International Society of Nephrology.
論文のバージョン	publisher
PubMed ID	39216659
DOI	10.1016/j.kint.2024.08.019
Web of Science KeyUT	001343408600001
関連URL	isVersionOf https://doi.org/10.1016/j.kint.2024.08.019

Methyl vinyl ketone and its analogs covalently modify PI3K and alter physiological functions by inhibiting PI3K signaling

フルテキストURL	fulltext.pdf
著者	Morimoto, Atsushi\| Takasugi, Nobumasa\| Pan, Yuexuan\| Kubota, Sho\| Dohmae, Naoshi\| Abiko, Yumi\| Uchida, Koji\| Kumagai, Yoshito\| Uehara, Takashi\|
キーワード	phosphatidylinositol 3-kinase (PI 3-kinase) cell signaling chemical modification autophagy glucose uptake
発行日	2024-03
出版物タイトル	Journal of Biological Chemistry
巻	300巻
号	3号
出版者	Elsevier
開始ページ	105679
ISSN	1083-351X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 THE AUTHORS.
論文のバージョン	publisher
PubMed ID	38272219
DOI	10.1016/j.jbc.2024.105679
Web of Science KeyUT	001345391900001
関連URL	isVersionOf https://doi.org/10.1016/j.jbc.2024.105679

Occult Nesidioblastosis Detected by 111In-Pentetreotide Single-Photon Emission Computed Tomography

JaLCDOI	10.18926/AMO/67667
フルテキストURL	78_5_423.pdf
著者	Sakamoto, Shinya\| Tabuchi, Motoyasu\| Yoshimatsu, Rika\| Hishida, Ai\| Matsumoto, Manabu\| Iwata, Jun\| Okabayashi, Takehiro\|
抄録	Nesidioblastosis, also known as persistent hyperinsulinemic hypoglycemia, is usually observed in children and infants, although more recently adult-onset nesidioblastosis has also been described. We present a case of nesidioblastosis in a 78-year-old man that was detected by 111In-pentetreotide single photon emission computed tomography (SPECT/CT). The patient was transferred to our hospital’s emergency department in a hypoglycemic coma. Dynamic enhanced CT could detect no lesion in the pancreas, but an 111In-pentetreotide SPECT/CT scan performed after a similar episode four weeks later showed increased focal uptake at the head of the pancreas. The results of a selective arterial calcium injection test were negative. After careful consideration and discussion among colleagues, surgical intervention was selected, and a pancreaticoduodenectomy was performed. On histology, there were elevated numbers of Langerhans islets in the pancreatic head, and the islets themselves appeared enlarged. Hypertrophic β-cells comprised the majority, but α-cells, δ-cells and pancreatic polypeptide were also detected in the islets. Based on the histopathological results and repeated hyperinsulinemic hypoglycemic crises, the patient was finally diagnosed with adult-onset nesidioblastosis. He had no hypoglycemic symptoms during outpatient follow-up examination. Since 111In-pentetreotide SPECT/CT may be able to detect nesidioblastosis, clinicians should consider this relatively new-modality examination when encountering such cases.
キーワード	111In-pentetreotide nesidioblastosis single-photon emission computed tomography hyperinsulinemic hypoglycemia
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2024-10
巻	78巻
号	5号
出版者	Okayama University Medical School
開始ページ	423
終了ページ	428
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	39467661
Web of Science KeyUT	001343346400009

Effect of Radon Inhalation on Murine Brain Proteins: Investigation Using Proteomic and Multivariate Analyses

JaLCDOI	10.18926/AMO/67663
フルテキストURL	78_5_387.pdf
著者	Naoe, Shota\| Tanaka, Ayumi\| Kanzaki, Norie\| Takenaka, Reiju\| Sakoda, Akihiro\| Miyaji, Takaaki\| Yamaoka, Kiyonori\| Kataoka, Takahiro\|
抄録	Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation.
キーワード	radon inhalation proteomics multivariate analysis brain oxidative stress
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-10
巻	78巻
号	5号
出版者	Okayama University Medical School
開始ページ	387
終了ページ	399
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	39467657
Web of Science KeyUT	001343346400005

GRP78 Contributes to the Beneficial Effects of SGLT2 Inhibitor on Proximal Tubular Cells in DKD

フルテキストURL	fulltext20240924-02.pdf fig20240924-02.pdf suppl_information20240924-02.pdf suppl_fig20240924-02.pdf
著者	Nakatsuka, Atsuko\| Yamaguchi, Satoshi\| Wada, Jun\|
備考	This is an Accepted Manuscript of an article published by American Diabetes Association.\|
発行日	2024-02-23
出版物タイトル	Diabetes
巻	73巻
号	5号
出版者	American Diabetes Association
開始ページ	763
終了ページ	779
ISSN	0012-1797
NCID	AA00628057
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 by the American Diabetes Association.
論文のバージョン	author
PubMed ID	38394641
DOI	10.2337/db23-0581
Web of Science KeyUT	001288274500014
関連URL	isVersionOf https://doi.org/10.2337/db23-0581

Histological differences related to autophagy in the minor salivary gland between primary and secondary types of Sjögren's syndrome

フルテキストURL	fulltext.pdf
著者	Ono-Minagi, Hitomi\| Nohno, Tsutomu\| Takabatake, Kiyofumi\| Tanaka, Takehiro\| Katsuyama, Takayuki\| Miyawaki, Kohta\| Wada, Jun\| Ibaragi, Soichiro\| Iida, Seiji\| Yoshino, Tadashi\| Nagatsuka, Hitoshi\| Sakai, Takayoshi\| Ohuchi, Hideyo\|
キーワード	Autoimmune disease Xerostomia Multiplex immunostaining Spatial analysis Autophagy
備考	The version of record of this article, first published in BMC Oral Health, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12903-024-04869-4\|
発行日	2024-09-16
出版物タイトル	BMC Oral Health
巻	24巻
号	1号
出版者	BMC
開始ページ	1099
ISSN	1472-6831
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024.
論文のバージョン	publisher
PubMed ID	39285388
DOI	10.1186/s12903-024-04869-4
Web of Science KeyUT	001314744100005
関連URL	isVersionOf https://doi.org/10.1186/s12903-024-04869-4

Illumina-based transcriptomic analysis of the fast-growing leguminous tree Acacia crassicarpa: functional gene annotation and identification of novel SSR-markers

フルテキストURL	fulltext.pdf
著者	Ishio, Shougo\| Kusunoki, Kazutaka\| Nemoto, Michiko\| Kanao, Tadayoshi\| Tamura, Takashi\|
キーワード	Acacia crassicarpa illumina sequencing polymorphism auxin response factor lignin
発行日	2024-08-29
出版物タイトル	Frontiers in Plant Science
巻	15巻
出版者	Frontiers Media
開始ページ	1339958
ISSN	1664-462X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 Ishio, Kusunoki, Nemoto, Kanao and Tamura.
論文のバージョン	publisher
PubMed ID	39268003
DOI	10.3389/fpls.2024.1339958
Web of Science KeyUT	001310352400001
関連URL	isVersionOf https://doi.org/10.3389/fpls.2024.1339958

Effect of Recipient Age on Perioperative Complications after Pediatric Liver Transplantation: A Single-Center Retrospective Study

JaLCDOI	10.18926/AMO/67548
フルテキストURL	78_4_323.pdf
著者	Katayama, Akira\| Kimura, Satoshi\| Matsusaki, Takashi\| Morimatsu, Hiroshi\|
抄録	It has not been clear how recipient age affects the incidence of serious complications after pediatric living donor liver transplantation (LDLT). We investigated the records of 42 pediatric patients receiving LDLT, dividing our sample into two groups: the infant group (aged < 1 year) and the non-infant group (aged ≥ 1 year and ≤15 years). The primary outcome was postoperative complications assessed using the Clavien-Dindo classification. Multivariate analysis using the Cox regression model was applied to adjust for confounding factors in assessing the incidence of Clavien-Dindo grade ≥ III (C-D ≥ III) complications. The incidence of C-D ≥ III complications was higher in the non-infant group (46.2%) than in the infant group (12.5%) (odds ratio 6.00, 95% confidence interval [CI] 1.13-31.88, p=0.03). In multivariate analysis using the Cox regression model, the Graft-to-Recipient Weight Ratio (GRWR) was independently associated with the incidence of C-D ≥ III complications (hazard ratio [HR] 0.62, 95%CI 0.40-0.95, p=0.03), but being an infant was not (HR 0.84, 95%CI 0.35-1.98, p=0.68). In conclusion, the incidence of C-D ≥ III complications was higher in the non-infant group than in the infant group, but this was largely a function of GRWR: multivariate analysis revealed that GRWR was independently associated with complications.
キーワード	pediatric liver transplantation postoperative severe complications Graft-to-Recipient Weight Ratio
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-08
巻	78巻
号	4号
出版者	Okayama University Medical School
開始ページ	323
終了ページ	330
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	39198986
Web of Science KeyUT	001310576400003

Increased Oxidative Stress and Decreased Citrulline in Blood Associated with Severe Novel Coronavirus Pneumonia in Adult Patients

フルテキストURL	fulltext.pdf
著者	Tsuge, Mitsuru\| Ichihara, Eiki\| Hasegawa, Kou\| Kudo, Kenichiro\| Tanimoto, Yasushi\| Nouso, Kazuhiro\| Oda, Naohiro\| Mitsumune, Sho\| Kimura, Goro\| Yamada, Haruto\| Takata, Ichiro\| Mitsuhashi, Toshiharu\| Taniguchi, Akihiko\| Tsukahara, Kohei\| Aokage, Toshiyuki\| Hagiya, Hideharu\| Toyooka, Shinichi\| Tsukahara, Hirokazu\| Maeda, Yoshinobu\|
キーワード	novel coronavirus disease 2019 pneumonia hydroperoxide nitric oxide reactive oxygen species citrulline arginine asymmetric dimethylarginine
発行日	2024-07-31
出版物タイトル	International Journal of Molecular Sciences
巻	25巻
号	15号
出版者	MDPI
開始ページ	8370
ISSN	1661-6596
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 by the authors.
論文のバージョン	publisher
PubMed ID	39125944
DOI	10.3390/ijms25158370
Web of Science KeyUT	001286890700001
関連URL	isVersionOf https://doi.org/10.3390/ijms25158370

Importance of Blood Glucose Measurement for Predicting the Prognosis of Long COVID: A Retrospective Study in Japan

フルテキストURL	fulltext.pdf
著者	Yokoyama, Sho\| Honda, Hiroyuki\| Otsuka, Yuki\| Tokumasu, Kazuki\| Nakano, Yasuhiro\| Sakurada, Yasue\| Matsuda, Yui\| Sunada, Naruhiko\| Hasegawa, Toru\| Takase, Ryosuke\| Omura, Daisuke\| Soejima, Yoshiaki\| Ueda, Keigo\| Kishida, Masayuki\| Otsuka, Fumio\|
キーワード	blood glucose diabetes mellitus long COVID omicron variant post-COVID-19 condition
発行日	2024-07-13
出版物タイトル	Journal of Clinical Medicine
巻	13巻
号	14号
出版者	MDPI
開始ページ	4099
ISSN	2077-0383
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 by the authors.
論文のバージョン	publisher
PubMed ID	39064139
DOI	10.3390/jcm13144099
Web of Science KeyUT	001278836700001
関連URL	isVersionOf https://doi.org/10.3390/jcm13144099

Mechanisms and Functions of Sweet Reception in Oral and Extraoral Organs

フルテキストURL	fulltext.pdf
著者	Yoshida, Ryusuke\| Ninomiya, Yuzo\|
キーワード	sweet taste energy homeostasis T1R3 GLUT SGLT sugar
発行日	2024-07-05
出版物タイトル	International Journal of Molecular Sciences
巻	25巻
号	13号
出版者	MDPI
開始ページ	7398
ISSN	1661-6596
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 by the authors.
論文のバージョン	publisher
PubMed ID	39000505
DOI	10.3390/ijms25137398
Web of Science KeyUT	001269731000001
関連URL	isVersionOf https://doi.org/10.3390/ijms25137398

地方創生第１期における企業の参入と撤退：回転ドア型経済か創造的破壊か

JaLCDOI	10.18926/OER/67485
タイトル（別表記）	Firm Entry and Exit in the First Stage of Regional Vitalization: Revolving Door Economy or Creative Destruction
フルテキストURL	oer_056_1_001_028.pdf
著者	中村良平\|
抄録	The growth of the regional economy needs an economic metabolism in which high-productivity firms newly enter the market, while low-productivity firms exit the market, resulting in a shift in labor and other production factors. A“ revolving door” economy is an economy in which firms that enter the market have a short existence period, withdraw and enter the market repeatedly, and new entrants do not contribute to productivity improvement. This means that if new entrants are not sufficiently innovative compared to incumbents, even if the rate of entry into business rises, they will simply be replaced by firms whose productivity level has not changed much, and this will not lead to job creation or improving productivity. A contrasting concept is the replacement of firms by Schumpeter's “creative destruction.” The high level of technology and productivity of new firms entering the market drives inefficient incumbents out of the market. Looking at the statistics, there is a tendency for both large cities to have higher business entry and exit rates, but the difference between the entry and exit rates is greater in metropolitan areas. Although it depends on the regional characteristics, location competitiveness is generally higher in metropolitan areas, and there is a tendency for the turnover rate to be high or the survival period to be short. Before and after regional revitalization, we will examine whether or not there is a departure from the revolving door economy by industry and region, using economic census and TSR （Tokyo Shoko Research） data.
出版物タイトル	岡山大学経済学会雑誌
発行日	2024-07-24
巻	56巻
号	1号
開始ページ	1
終了ページ	28
ISSN	2433-4146
言語	日本語
著作権者	Copyright © 2024 岡山大学経済学会
論文のバージョン	publisher

A case of membranous nephropathy complicated by Cronkhite–Canada syndrome successfully treated with mizoribine

フルテキストURL	fulltext20240716-04.pdf fig20240716-04.pdf
著者	Nakanoh, Hiroyuki\| Tsuji, Kenji\| Morimoto, Shiho\| Fukushima, Kazuhiko\| Iwamuro, Masaya\| Uchida, Haruhito A.\| Wada, Jun\|
キーワード	Cronkhite–Canada syndrome Membranous nephropathy Nephrotic syndrome Mizoribine
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s13730-024-00908-9\| This fulltext file will be available in Jul. 2025.\|
発行日	2024-07-02
出版物タイトル	CEN Case Reports
巻	14巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	72
終了ページ	80
ISSN	2192-4449
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s), under exclusive licence to Japanese Society of Nephrology 2024
論文のバージョン	author
PubMed ID	38954395
DOI	10.1007/s13730-024-00908-9
Web of Science KeyUT	001261218500001
関連URL	isVersionOf https://doi.org/10.1007/s13730-024-00908-9

Unabsorbed Fecal Fat Content Correlates with a Reduction of Immunoglobulin a Coating of Gut Bacteria in High‐Lard Diet‐Fed Mice

フルテキストURL	fulltext20240716-01.pdf
著者	Katsumata, Emiko\| Tsuruta, Takeshi\| Sonoyama, Kei\| Yoshida, Takashi\| Sasaki, Mio\| Teraoka, Mao\| Wang, Tianyang\| Nishino, Naoki\|
キーワード	gut bacteria immunoglobulin A lard
備考	This is the peer reviewed version of the following article: E. Katsumata, T. Tsuruta, K. Sonoyama, T. Yoshida, M. Sasaki, M. Teraoka, T. Wang, N. Nishino, Unabsorbed Fecal Fat Content Correlates with a Reduction of Immunoglobulin a Coating of Gut Bacteria in High-Lard Diet-Fed Mice. Mol. Nutr. Food Res. 2024, 68, 2400078. https://doi.org/10.1002/mnfr.202400078, which has been published in final form at https://doi.org/10.1002/mnfr.202400078. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.\| This fulltext file will be available in Jul. 2025.\|
発行日	2024-07-04
出版物タイトル	Molecular Nutrition & Food Research
巻	68巻
号	15号
出版者	Wiley
開始ページ	2400078
ISSN	1613-4125
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 Wiley-VCH GmbH
論文のバージョン	author
PubMed ID	38965658
DOI	10.1002/mnfr.202400078
Web of Science KeyUT	001262016700001
関連URL	isVersionOf https://doi.org/10.1002/mnfr.202400078

Late-onset renal variant Fabry disease with R112H mutation and mild increase in plasma globotriaosylsphingosine: a case report

フルテキストURL	fulltext.pdf
著者	Tanaka, Keiko\| Sugiyama, Hitoshi\| Morinaga, Hiroshi\| Onishi, Akifumi\| Tanabe, Katsuyuki\| Uchida, Haruhito A.\| Maruyama, Hiroki\| Wada, Jun\|
キーワード	Fabry disease R112H mutation migalastat proteinuria chronic kidney disease
発行日	2024-06-06
出版物タイトル	Frontiers in Medicine
巻	11巻
出版者	Frontiers Media
開始ページ	1383309
ISSN	2296-858X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 Tanaka, Sugiyama, Morinaga, Onishi, Tanabe, Uchida, Maruyama and Wada.
論文のバージョン	publisher
PubMed ID	38903807
DOI	10.3389/fmed.2024.1383309
Web of Science KeyUT	001250041200001
関連URL	isVersionOf https://doi.org/10.3389/fmed.2024.1383309

Effect of Humidified High-Flow Nasal Cannula Oxygen Therapy with a Pulmonary Infection Control Window as a Ventilation Switching Indication in Combination with Atomizing Inhalation of Terbutaline on the Lung Function of Patients with Acute Exacerbation of COPD

JaLCDOI	10.18926/AMO/67202
フルテキストURL	78_3_271.pdf
著者	Ye, Mengjiao\| Zhang, Renwei\|
抄録	We investigated how humidified high-flow nasal cannula oxygen therapy (HFNC) with a pulmonary infection control (PIC) window as a ventilation switching indication in combination with atomizing inhalation of terbutaline affects the lung function of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We examined 140 hospitalized AECOPD patients randomized to control and observation groups. Conventional supportive therapy and invasive mechanical ventilation with tracheal intubation were conducted in both groups, with a PIC window as the indication for ventilation switching. Noninvasive positive pressure ventilation (NIPPV) plus atomizing inhalation of terbutaline was used in the control group. In the observation group, HFNC combined with atomizing inhalation of terbutaline was used. Compared to the control group, after 48-hr treatment and treatment completion, the observation group had significantly increased levels of lung function indicators (maximal voluntary ventilation [MVV] plus forced vital capacity [FVC], p<0.05) and oxygen metabolism indicators (arterial oxygen partial pressure [PaO2], arterial oxygen content [CaO2], and oxygenation index, p<0.05). The comparison of the groups revealed that the levels of airway remodeling indicators (matrix metalloproteinase-2 [MMP-2], tissue inhibitor of metalloproteinase 2 [TIMP-2] plus MMP-9) and inflammatory indicators (interferon gamma [IFN-γ] together with interleukin-17 [IL-17], IL-10 and IL-4) were significantly lower after 48 h of treatment as well as after treatment completion (both p<0.05). These results demonstrate that HFNC with a PIC window as the indication for ventilation switching combined with atomizing inhalation of terbutaline can relieve the disorder of oxygen metabolism and correct airway hyper-reactivity.
キーワード	chronic obstructive pulmonary disease inhalation oxygen therapy pulmonary function ventilation
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-06
巻	78巻
号	3号
出版者	Okayama University Medical School
開始ページ	271
終了ページ	279
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38902215
Web of Science KeyUT	001267351000008