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JaLCDOI 10.18926/AMO/56252
フルテキストURL 72_5_525.pdf
著者 Kakutani, Rika| Kondo, Naoki| Mochizuki, Tomoharu| Fujisawa, Junichi| Endo, Naoto|
抄録 The bilateral shoulder pain of an 81-year-old Japanese woman due to falls persisted despite celecoxib treatment, and plain X-rays later showed bilateral collapsed humeral heads. After ruling out osteoarthritis, infectious arthritis, crystal-induced arthritis, neuropathic arthropathy, and osteonecrosis, we diagnosed bilateral shoulder joint rapidly destructive arthrosis (RDA). Lumbar bone mineral density showed very low T-score (−4.1). Primary osteoporosis was observed. Histology of biopsied humeral head indicated the features of fracture healing process: callus formation and osteoclasts without empty lacunae. Her history thus included an insufficiency fracture due to severe osteoporosis. Bilateral humeral head replacement was performed; her shoulder joint function improved. This case is extremely rare in that RDA was caused by simultaneous bilateral shoulder joint collapse within a very short time, with minimal or low mechanical stress and severe osteoporosis.
キーワード rapidly destructive arthrosis differential diagnosis humeral head replacement osteoporosis shoulder joint
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2018-10
72巻
5号
出版者 Okayama University Medical School
開始ページ 525
終了ページ 530
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30369611
JaLCDOI 10.18926/AMO/56251
フルテキストURL 72_5_519.pdf
著者 Miyahara, Hiroyuki| Tokumasu, Hironobu| Chin, Masaki| Waki, Kenji| Arakaki, Yoshio|
抄録 Cases of recurrent meningitis in elderly patients with a spontaneous cerebrospinal fistula have been reported, and in some of these patients, cystic lesions were thought to be the underlying cause. We report a case of recurrent meningitis in an 11-year-old Japanese girl with an arachnoid cyst in the petrous apex. Pulsation of the cystic lesion was thought to cause bone erosion, leading to the formation of a fistula. Magnetic resonance imaging was useful in evaluating the arachnoid cyst and fistula. During 2 years of follow-up, the osteolytic lesion enlarged and the rate of bone erosion was higher than expected.
キーワード magnetic resonance imaging pulsation of cystic lesion bone erosion fistula
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2018-10
72巻
5号
出版者 Okayama University Medical School
開始ページ 519
終了ページ 523
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30369610
JaLCDOI 10.18926/AMO/56249
フルテキストURL 72_5_507.pdf
著者 Ogata, Takeshi| Katsui, Kuniaki| Yoshio, Kotaro| Ihara, Hiroki| Katayama, Norihisa| Soh, Junichi| Kuroda, Masahiro| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu|
抄録 To clarify the relationship between dose-volume histogram (DVH) parameters and radiation pneumonitis (RP) after surgery in cases of non-small cell lung cancer (NSCLC) treated with induction concurrent chemoradiotherapy (CCRT). Patients with NSCLC treated with induction CCRT (chemotherapy: cisplatin and docetaxel; radiotherapy: 2.0 Gy fractions once daily for a total of 46 Gy) before surgery were reviewed. We calculated the percentage of lung volume receiving at least 20 Gy (V20) and the mean lung dose (MLD) for the total lung volume and the lung remaining after resection. Factors affecting the incidence of RP at grade 2 or higher (≥ G2 RP) were analyzed. Eighteen of 49 patients (37%) experienced ≥G2 RP. The V20 and MLD for the lung remaining after resection (V20r and MLDr) were significant predictors according to the multivariate analysis (p=0.007 and 0.041, respectively). The incidence of ≥G2 RP was 8% in patients with V20r<10%, and 13% in patients with MLDr<5.6 Gy, respectively. The optimal approach to reduce the rate of postoperative RP in patients with induction CCRT for NSCLC is to keep the V20r below 10% and/or the MLDr below 5.6 Gy in the radiotherapy planning.
キーワード radiation pneumonitis V20 mean lung dose induction chemoradiotherapy non-small cell lung cancer
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-10
72巻
5号
出版者 Okayama University Medical School
開始ページ 507
終了ページ 513
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30369608
JaLCDOI 10.18926/AMO/56248
フルテキストURL 72_5_499.pdf
著者 Kodama, Yuya| Furumatsu, Takayuki| Maehara, Ami| Ozaki, Toshifumi|
抄録 Cell clusters, or groups of cells sharing a single chondron-like structure, are frequently found in degenerated areas of the osteoarthritic (OA) meniscus. However, little is known about these meniscal clusters in humans. The aim of our study was to determine the composition of the extracellular matrix deposition around cell clusters in human OA menisci. Twenty-six menisci were obtained through total knee arthroplasty from patients with OA knee joints. The specimens were subjected to safranin O staining and immunostaining for Sry-type HMG box 9 (SOX9), type II collagen, and aggrecan. Their signal density after staining was assessed using ImageJ software. Five regions of interest were analyzed within each tissue sample. The SOX9, type II collagen, and aggrecan densities were considerably higher in cluster areas than in intact superficial layers of the meniscus. In addition, a substantial difference was detected between cluster areas and degenerative areas without cell clusters. We demonstrated that cell clusters localized near fissures and clefts showed remarkable uniformity in menisci exposed to a broad range of injuries. In addition, the chondrogenic proteins SOX9, type II collagen, and aggrecan were highly expressed in these tissues.
キーワード cell cluster meniscus osteoarthritis Sry-type HMG box 9 type II collagen
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-10
72巻
5号
出版者 Okayama University Medical School
開始ページ 499
終了ページ 506
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30369607
JaLCDOI 10.18926/AMO/56247
フルテキストURL 72_5_493.pdf
著者 Okazaki, Yuki| Furumatsu, Takayuki| Masuda, Shin| Miyazawa, Shinichi| Kodama, Yuya| Kamatsuki, Yusuke| Hino, Tomohito| Okazaki, Yoshiki| Ozaki, Toshifumi|
抄録 Medial meniscus (MM) posterior root tear (PRT) results in joint overloading and degenerative changes in the knee. MM root repair is recommended to prevent subsequent cartilage degeneration following MMPRT. Favorable clinical outcomes have been reported after transtibial pullout repair of MMPRT. However, it is unclear whether pullout repair can cause compositional change in the MM posterior segment. We examined this question in 14 patients who underwent MMPRT pullout repair. Magnetic resonance imaging examinations were performed preoperatively and 3 months postoperatively at 10° knee flexion. The region-of-interest was marked along the MM posterior segment edge. Intra-meniscal signal intensity (IMSI) was expressed as the signal intensity ratio of the repaired MM to the intact lateral meniscus, which was used as a control. MMPRT pullout repair reduced IMSI from 1 to 0.915±0.096 (range, 0.760-1.074) 3 months postoperatively (p=0.006, power=0.90). Meniscal degeneration causes high proton density-weighted imaging signal intensity of the meniscal body. In our study, MMPRT pullout repair reduced IMSI contrary to other tears. This technique may decrease the MM posterior segment signal intensity by restoring the hoop tension mechanism. Measuring IMSI may be useful to assess the effect of MMPRT pullout repair on meniscal healing.
キーワード medial meniscus posterior root tear magnetic resonance imaging signal intensity arthroscopic surgery
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-10
72巻
5号
出版者 Okayama University Medical School
開始ページ 493
終了ページ 498
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30369606
JaLCDOI 10.18926/AMO/56246
フルテキストURL 72_5_487.pdf
著者 Hamasaki, Ichiro| Shibata, Kiyo| Shimizu, Takehiro| Morisawa, Shin| Toshima, Shinji| Miyata, Manabu| Furuse, Takashi| Hasebe, Satoshi| Ohtsuki, Hiroshi| Morizane, Yuki| Shiraga, Fumio|
抄録 We investigated variances in the stability and amount of postoperative exodrift among age groups of intermittent exotropia (XPT) patients who underwent unilateral lateral rectus muscle recession and medial rectus muscle resection. We analyzed the cases of 110 consecutive patients who underwent the surgery in 2004-2011, dividing the patients into groups by their age at surgery: <10, 10-19, and ≥20 years. We performed a regression analysis (dependent variable: postoperative exodrift (°); independent variable: number of days post-surgery) using the formula of curve lines. When the tangent line slope was = 0.01 (°/days) for each group, we defined the numbers of days until alignment became stable as the ‘stable days.’ We evaluated the between-group differences in the amount of exodrift calculated for the stable days. The coefficients and coefficients of determination for the fitting curves were: <10 year group: f(x)=12.2 (1−e−0.0183x) (r2=0.588, p<0.05); 10-19 year group: f(x)=10.0 (1−e−0.0178x) (r2=0.453, p<0.05); ≥20 year group: f(x)=3.40 (1−e−0.0382x) (r2=0.217, p<0.05). There were 389 , 388, and 153 stable days, and the estimated postoperative exodrift with long-term follow-up was 11.5±3.7°, 9.3±4.4°, and 4.1±3.6° for the < 10 year, 10-19 year, and ≥ 20 year groups, respectively (≥20 year vs. other 2 groups, p<0.05). Longer periods and more postoperative exodrift were associated with younger age at surgery. The postoperative evaluation was approx. ≥ 1 year post-surgery in patients aged < 20. These findings may contribute to evaluating XPT’s success rate and prognoses.
キーワード intermittent exotropia postoperative exodrift recession resection procedure strabismus surgery
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-10
72巻
5号
出版者 Okayama University Medical School
開始ページ 487
終了ページ 492
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30369605
JaLCDOI 10.18926/AMO/56244
フルテキストURL 72_5_467_n.pdf
著者 Vika Fatafehi Hala’ufia Lemoto| Sugimoto, Kentaro| Kanazawa, Tomoyuki| Matsuzaki, Takashi| Morimatsu, Hiroshi|
抄録 We investigated the incidence of desaturation during general anesthesia in preoperatively hypoxic (< 92%), and nonhypoxic (≥ 92%) pediatric (n=1,090) and adult (n=5,138) patients. We plotted the patients’ SpO2 value time-courses and assessed desaturation in 6,228 patients. The crude overall incidence (95%CI) for desaturation was 11.1% (9.4-13.1) in the pediatric patients and 0.9% (0.6-1.2) in the adults. The crude incidence of desaturation in the hypoxic pediatric patients was 2.5 times the risk in the nonhypoxic patients: risk ratio (RR) 2.5 (1.8-3.5), p<0.001. The risk of desaturation in the hypoxic adult patients was 20.1 times the risk in the nonhypoxic adult patients: RR 20.1 (10.3-39.2), p<0.001. When the patients were separately stratified by American Society of Anesthesiologists Physical Status (ASA-PS) and by age, the directly adjusted risk-ratio (RRS) showed that the hypoxic pediatric patients had 1.8 and 1.6 times the risk in the nonhypoxic pediatric patients: ASA-PS adjusted RRS 1.6 (1.8-2.2), p<0.001; age-adjusted RRS 1.8 (1.3-2.5), p<0.001, and the hypoxic adult patients had 13.8 times the risk in the nonhypoxic adult patients: RRS 13.8 (6.9-27.6), p<0.001. A pulse-oximeter check before the start of general anesthesia could ensure timely preparation to avoid intraoperative desaturation.
キーワード desaturation incidence pulse oximetry general anesthesia adult pediatric
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-10
72巻
5号
出版者 Okayama University Medical School
開始ページ 467
終了ページ 478
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30369603
JaLCDOI 10.18926/AMO/56243
フルテキストURL 72_5_457.pdf
著者 Muto, Noriko| Matsuoka, Yoshikazu| Arakawa, Kyosuke| Kurita, Masako| Omiya, Hiroki| Taniguchi, Arata| Kaku, Ryuji| Morimatsu, Hiroshi|
抄録 Quercetin is a flavonoid widely found in plants and marketed to the public as a supplement. Several studies have reported its effect on glial cells. This study aimed to examine the effect of quercetin on the development of neuropathic pain and the underlying mechanism in a spared nerve injury (SNI) rat model. Male Sprague-Dawley rats randomly assigned to the control or the quercetin group were subjected to SNI of the sciatic nerve. We measured pain behaviors on the hind paw and glial fibrillary acidic protein (GFAP) in the dorsal root ganglion (DRG) and spinal cord. Oral administration of 1% quercetin, begun before surgery, attenuated mechanical allodynia compared to the control group at days 7 and 10 after SNI. On the other hand, established pain was not attenuated in a post-dose group in which quercetin was begun 7 days after SNI. Quercetin inhibited GFAP in the satellite glial cells of the ipsilateral L5 DRG on day 7 compared to the control group. Quercetin suppressed the development of neuropathic pain through a mechanism partly involving the inhibition of satellite glial cells. As its safety is well established, quercetin has great potential for clinical use in pain treatment.
キーワード flavonoid dorsal root ganglion glial fibrillary acidic protein alternative medicine
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-10
72巻
5号
出版者 Okayama University Medical School
開始ページ 457
終了ページ 465
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30369602
JaLCDOI 10.18926/AMO/56242
フルテキストURL 72_5_447.pdf
著者 Oka, Kosuke| Hanayama, Yoshihisa| Sato, Asuka| Omura, Daisuke| Yasuda, Miho| Hasegawa, Ko| Obika, Mikako| Otsuka, Fumio|
抄録 We retrospectively analyzed the cases of 148 febrile patients whose body temperature (BT) was ≥ 37.5°C at our hospital. We categorized them into seven groups; those with bacterial and viral infection, nonspecific inflammation, neoplasm, connective tissue disease (CTD), drug-induced disease, and unidentified causes. Our analysis revealed that the patient’s BT at the 1st visit (BT-1st visit) and highest BT during the febrile period (BT-max) differed significantly among all categories except neoplasm. The greatest difference between BT-1st visit and BT-max was highest in the CTD group (1.5°C). Positive correlations of heart rate and C-reactive protein (CRP) level with BT-max and a negative correlation between serum sodium level with BT-max were uncovered. The serum thyroid-stimulating hormone (TSH) level and the ratio of TSH/free thyroxine were negatively correlated with BT-max, especially in the viral infection group, suggesting the existence of occult thyrotoxicosis in accord with a febrile condition, possibly leading to febrile tachycardia. A febrile gap between BT-1st visit and BT-max (except in the neoplasm group) was shown, in which BT-max was correlated with thyroid function. Clinicians should recognize the fluctuation of BT when diagnosing febrile patients, and tachycardia in such febrile patients may be, at least in part, associated with subclinical thyroid dysfunction.
キーワード body temperature C-reactive protein fever of unknown origin tachycardia thyroid dysfunction
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2018-10
72巻
5号
出版者 Okayama University Medical School
開始ページ 447
終了ページ 456
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2018 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 30369601
フルテキストURL bfsc_039_055_058.pdf
著者 岡山大学農学部附属山陽圏フィールド科学センター |
出版物タイトル 岡山大学農学部センター報告
発行日 2017-04-01
39巻
開始ページ 55
終了ページ 58
ISSN 0910-8742
言語 日本語
著作権者 岡山大学農学部
論文のバージョン publisher
フルテキストURL bfsc_039_015_054.pdf
著者 岡山大学農学部附属山陽圏フィールド科学センター |
出版物タイトル 岡山大学農学部センター報告
発行日 2017-04-01
39巻
開始ページ 15
終了ページ 54
ISSN 0910-8742
言語 日本語
著作権者 岡山大学農学部
論文のバージョン publisher
フルテキストURL bfsc_039_001_007.pdf
著者 岡山大学農学部附属山陽圏フィールド科学センター |
出版物タイトル 岡山大学農学部センター報告
発行日 2017-04-01
39巻
開始ページ 1
終了ページ 7
ISSN 0910-8742
言語 日本語
著作権者 岡山大学農学部
論文のバージョン publisher
タイトル(別表記) The Concept of Dividend in Japanese Income Tax : Past, Now and Future;
フルテキストURL ronsyu_74_217.pdf
著者 小塚 真啓|
発行日 2018-09-20
出版物タイトル 日税研論集
74号
出版者 日本税務研究センター
開始ページ 217
終了ページ 249
ISSN 0912-9685
NCID AN10032022
資料タイプ 学術雑誌論文
言語 日本語
OAI-PMH Set 岡山大学
論文のバージョン publisher
JaLCDOI 10.18926/OLR/56227
タイトル(別表記) How can Local Public Entities Constitutionally Regulate the Dispersion of Ashes of the Dead?
フルテキストURL olr_021_111_128.pdf
著者 田近 肇|
出版物タイトル 臨床法務研究
発行日 2018-09
21巻
開始ページ 111
終了ページ 128
ISSN 1881-1485
言語 日本語
論文のバージョン publisher
NAID 120006528318
JaLCDOI 10.18926/OLR/56226
タイトル(別表記) Appeals Judge for National Tax Tribunal as Lawyer’s Carrer
フルテキストURL olr_021_083_110.pdf
著者 中井 陽|
出版物タイトル 臨床法務研究
発行日 2018-09
21巻
開始ページ 83
終了ページ 110
ISSN 1881-1485
言語 日本語
論文のバージョン publisher
NAID 120006528317
JaLCDOI 10.18926/OLR/56225
タイトル(別表記) Overview of National Tax Appeal System
フルテキストURL olr_021_069_082.pdf
著者 奥田 芳彦|
出版物タイトル 臨床法務研究
発行日 2018-09
21巻
開始ページ 69
終了ページ 82
ISSN 1881-1485
言語 日本語
論文のバージョン publisher
NAID 120006528316
JaLCDOI 10.18926/OLR/56224
タイトル(別表記) Message from the Legal Department of a Global Company
フルテキストURL olr_021_055_067.pdf
著者 佐藤 厚|
出版物タイトル 臨床法務研究
発行日 2018-09
21巻
開始ページ 55
終了ページ 67
ISSN 1881-1485
言語 日本語
論文のバージョン publisher
NAID 120006528315
JaLCDOI 10.18926/OLR/56223
タイトル(別表記) Torts Liability of Person with Parental Authority for Traffic Accidents Caused by a Minor with Capacity to Assume Liability
フルテキストURL olr_021_017_054.pdf
著者 妻鹿 安希子|
出版物タイトル 臨床法務研究
発行日 2018-09
21巻
開始ページ 17
終了ページ 54
ISSN 1881-1485
言語 日本語
論文のバージョン publisher
NAID 120006528314
フルテキストURL Jo_ISCP_2018_161.pdf
著者 加藤 禎久|
キーワード green infrastructure sustainability urbanization landscape ecology connectivity multi-scale approach
発行日 2011-08
出版物タイトル Journal of the 2011 International Symposium on City Planning
2011巻
出版者 Korea Planners Association
開始ページ 161
終了ページ 170
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
論文のバージョン author
タイトル(別表記) Übersetzung von Jherings Briefe(2)
フルテキストURL olj_68_1_(043)_(079).pdf
著者 平田 公夫|
出版物タイトル 岡山大學法學會雜誌
発行日 2018-09-07
68巻
1号
開始ページ 124
終了ページ 88
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 120006517778