検索結果 14865 件
| JaLCDOI | 10.18926/AMO/53526 |
|---|---|
| フルテキストURL | 69_3_183.pdf |
| 著者 | Haruma, Tomoko| Ogawa, Chikako| Nishida, Takeshi| Kusumoto, Tomoyuki| Nakamura, Keiichiro| Seki, Noriko| Katayama, Takaaki| Hiramatsu, Yuji| |
| 抄録 | Pure ovarian choriocarcinoma is an extremely rare malignancy that can be gestational or non-gestational in origin. Silver-Russell syndrome (SRS) is a rare congenital developmental disorder characterized by pre- and postnatal growth failure, relative macrocephaly, a triangular face, hemihypotrophy, and fifth-finger clinodactyly. We report a rare case of pure ovarian choriocarcinoma occurring in a 19-year-old woman with SRS. Following surgery, multiple chemotherapy courses were effective and she was free of disease at the 10-month follow-up. |
| キーワード | choriocarcinoma ovary Silver-Russell syndrome |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 183 |
| 終了ページ | 188 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101195 |
| Web of Science KeyUT | 000356903000008 |
| JaLCDOI | 10.18926/AMO/53525 |
|---|---|
| フルテキストURL | 69_3_177.pdf |
| 著者 | Hoshijima, Mitsuhiro| Honjo, Tadashi| Moritani, Norifumi| Iida, Seiji| Yamashiro, Takashi| Kamioka, Hiroshi| |
| 抄録 | This article reports the case of a 44-year-old male with skeletal Class III, Angle Class III malocclusion and unilateral crossbite with concerns about obstructive sleep apnea syndrome (OSAS), esthetics and functional problems. To correct the skeletal deformities, the maxilla was anteriorly repositioned by employing LeFort I osteotomy following pre-surgical orthodontic treatment, because a mandibular setback might induce disordered breathing and cause OSAS. After active treatment for 13 months, satisfactory occlusion was achieved and an acceptable facial and oral profile was obtained. In addition, the apnea hypopnea index (AHI) decreased from 18.8 preoperatively to 10.6 postoperatively. Furthermore, after a follow-up period of 7 months, the AHI again significantly decreased from 10.6 to 6.2. In conclusion, surgical advancement of the maxilla using LeFort I osteotomy has proven to be useful in patients with this kind of skeletal malocclusion, while preventing a worsening of the OSAS. |
| キーワード | LeFort I osteotomy maxillary advancement unilateral crossbite obstructive sleep apnea syndrome |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 177 |
| 終了ページ | 182 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101194 |
| Web of Science KeyUT | 000356903000007 |
| JaLCDOI | 10.18926/AMO/53524 |
|---|---|
| フルテキストURL | 69_3_173.pdf |
| 著者 | Shirakawa, Yasuhiro| Noma, Kazuhiro| Ohara, Toshiaki| Kashima, Hajime| Maeda, Naoaki| Tanabe, Shunsuke| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| 抄録 | A chyle leak can occur as a complication after neck or chest surgery. Such a leak prolongs the hospital stay and is sometimes life-threatening. The treatment options are conservative management, interventional radiologic embolization, and surgery. Thoracoscopic ligation of the thoracic duct has emerged as a promising and definitive treatment. The case of a 65-year-old Japanese male patient with a rare congenital right aortic arch (typeⅢB1 of Edwardʼs classification) and a severe chyle leak that occurred after a total pharyngolaryngo-esophagectomy (TPLE) is described. The chyle leak was successfully managed by thoracoscopic ligation of the thoracic duct via a left-side approach with the patient in the prone position. |
| キーワード | chyle leak thoracic duct thoracoscopy prone position |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 173 |
| 終了ページ | 176 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101193 |
| Web of Science KeyUT | 000356903000006 |
| JaLCDOI | 10.18926/AMO/53523 |
|---|---|
| フルテキストURL | 69_3_165.pdf |
| 著者 | Sarai, Takaaki| Tokumoto, Akihiro| |
| 抄録 | Fall accidents are a common cause of femoral fracture in the elderly. The greater trochanter of the femur is often subjected to impact loading by a sideways fall, and thus it is worth studying the impulsive stress waves propagating in the femur. In this study, the impulsive stress was analyzed by the dynamic finite element method using a 3-dimensional model of the femur, and the influence of the fall configuration on the stress was discussed. The stress was concentrated around the femoral neck during the propagation of the stress wave, and the tensile maximum principal stress changed into compressive minimum principle stress on the anterior and medial sides of the neck. On the other hand, the compressive minimum principal stress changed into tensile maximum principle stress on the lateral side of the neck. The largest maximum principal stress during the impact loading was always larger in the neck than in the impact region. The largest absolute value of the minimum principal stress was found in the neck or the impact region depending on the fall configuration. The largest absolute values of the maximum and minimum principal stress were nearly equal, indicating that the bone fracture due to the tensile stress may occur around the femoral neck. |
| キーワード | biomechanics sideways fall femoral neck greater trochanter impulsive stress wave |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 165 |
| 終了ページ | 171 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101192 |
| Web of Science KeyUT | 000356903000005 |
| JaLCDOI | 10.18926/AMO/53522 |
|---|---|
| フルテキストURL | 69_3_155.pdf |
| 著者 | Mikamo, Shoko| Nakatsuka, Mikiya| |
| 抄録 | To assess the knowledge and attitudes of pregnant Japanese women regarding non-invasive prenatal testing (NIPT). Between March and June 2013, 557 pregnant women in the Hyogo and Hiroshima Prefectures were surveyed using an anonymous, self-completed questionnaire. A total of 91.9ｵ respondents (512/557) stated that they “agree” or “conditionally agree” with NIPT implementation in Japan. Approximately 28.5ｵ of respondents stated that they knew that the accuracy of a positive NIPT result can be affected by motherʼs age and background, while 34.5ｵ of respondents stated that it was necessary for pregnant women with a positive result to undergo fetal chromosome diagnosis using amniocentesis;both percentages were low. Additionally, 92.3ｵ of respondents would “like a detailed explanation of the test,” 65.1ｵ of them would “like psychological support if the NIPT test results came back positive,” and 5.7ｵ would terminate the pregnancy if the NIPT test results came back positive without undergoing fetal chromosome diagnosis via amniocentesis. Although a high proportion of pregnant Japanese women agreed with the introduction of NIPT into Japanese obstetrical care, there was insufficient knowledge regarding the test. It is necessary for women undergoing NIPT to be provided sufficient information and psychological support. |
| キーワード | amniocentesis Down syndrome fetal chromosome diagnosis non-invasive prenatal testing psychological support |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 155 |
| 終了ページ | 163 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101191 |
| Web of Science KeyUT | 000356903000003 |
| JaLCDOI | 10.18926/AMO/53521 |
|---|---|
| フルテキストURL | 69_3_145.pdf |
| 著者 | Ishii, Hiroko| Kamikawa, Shigeshi| Hirohata, Satoshi| Mizutani, Akifumi| Abe, Koji| Seno, Masaharu| Oohashi, Toshitaka| Ninomiya, Yoshifumi| |
| 抄録 | Eosinophil cationic protein (ECP) is well known as a cationic protein contained in the basic granules of activated eosinophils. Recent studies have reported that ECP exhibits novel activities on various types of cells, including rat neonatal cardiomyocytes. Here we evaluated the effects of ECP on rat cardiac myoblast H9c2 cells. Our results showed that ECP enhanced the survival of the cells, in part by promoting the ERK and Akt/GSK-3β signaling pathways. ECP attenuated the cytotoxic effects of H2O2 on H9c2 cells as well as the production of reactive oxygen species, the number of apoptotic cells and caspase 3/7 activity in the cells. In conclusion, ECP activated the ERK and Akt/GSK-3β pathways, resulting in anti-oxidative effects on H9c2 cells that attenuated apoptosis. |
| キーワード | ECP reactive oxygen species Akt ERK |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 145 |
| 終了ページ | 153 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101190 |
| Web of Science KeyUT | 000356903000003 |
| JaLCDOI | 10.18926/AMO/53520 |
|---|---|
| フルテキストURL | 69_3_137.pdf |
| 著者 | Seki, Hiroyuki| Ikeda, Fusao| Nanba, Shintaro| Moritou, Yuki| Takeuchi, Yasuto| Yasunaka, Tetsuya| Onishi, Hideki| Miyake, Yasuhiro| Takaki, Akinobu| Nouso, Kazuhiro| Iwasaki, Yoshiaki| Nakamura, Minoru| Yamamoto, Kazuhide| |
| 抄録 | A predictive marker of the rapid progression to hepatic failure is desired for patients with asymptomatic primary biliary cirrhosis (aPBC). We performed a systematic cohort analysis of 101 patients diagnosed as having aPBC and the rapid progression to liver failure in some, by focusing on cholestasis. Cholestasis was assessed by aberrant keratin7 (K-7) expressions in the patientsʼ hepatocytes. Intralobular expressions of K-7 were found in 9 of the 101 patients. The grades of K-7 expression were significantly associated with the levels of alanine aminotransferase, alkaline phosphatase, and total bilirubin at the time of diagnosis, but not with bile duct loss or cholestasis. Stepwise logistic regression analysis revealed that high grades of K-7 expression correlated positively with high levels of total bilirubin. During the follow-up period, 8 patients developed jaundice, and the mean period until the development of jaundice was 5.2 years. The proportional hazards models for the risk of developing jaundice identified a high grade of aberrant K-7 expression in hepatocytes as the only significant risk factor. Aberrant K-7 expression in hepatocytes can be used as an additional marker to predict rapid progression to liver failure in patients with aPBC at the time of diagnosis. |
| キーワード | primary biliary cirrhosis keratin 7 hepatic failure |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 137 |
| 終了ページ | 144 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101189 |
| Web of Science KeyUT | 000356903000002 |
| JaLCDOI | 10.18926/AMO/53519 |
|---|---|
| フルテキストURL | 69_3_129.pdf |
| 著者 | Akagi, Satoshi| Nakamura, Kazufumi| Matsubara, Hiromi| Ogawa, Aiko| Sarashina, Toshihiro| Ejiri, Kentaro| Ito, Hiroshi| |
| 抄録 | Pulmonary arterial hypertension (PAH) is characterized by elevation of pulmonary artery pressure caused by pulmonary vasoconstriction and vascular remodeling, which leads to right heart failure and death. Epoprostenol (prostaglandin I2) has a potent short-acting vasodilator property, and intravenous continuous epoprostenol is therefore used for treatment of PAH. Here we review evidence for the usefulness of intravenous continuous epoprostenol therapy in patients with PAH. Epoprostenol therapy is effective in idiopathic PAH patients and in patients with PAH associated with connective tissue disease, portal hypertension or congenital heart diseases, but it is not effective in patients with pulmonary veno-occlusive disease or pulmonary capillary hemangiomatosis. High-dose epoprostenol therapy markedly improved hemodynamics in some patients with PAH, possibly due to reverse remodeling of pulmonary arteries. This therapy has several side effects and complications such as headache, hypotension and catheter-related infections. Intravenous continuous epoprostenol is an effective treatment, but there are still some problems to be resolved. |
| キーワード | pulmonary arterial hypertension epoprostenol high-dose complications side effects |
| Amo Type | Review |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-06 |
| 巻 | 69巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 129 |
| 終了ページ | 136 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26101188 |
| Web of Science KeyUT | 000356903000001 |
| 著者 | 座間味 義人| 高取 真吾| 合田 光寛| 小山 敏広| 岩谷 有希子| Jin, Xin| Takada-Doi, Shima| 川﨑 博己| |
|---|---|
| 発行日 | 2008-11-01 |
| 出版物タイトル | Biological & Pharmaceutical Bulletin |
| 巻 | 31巻 |
| 号 | 11号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 全 成坤| |
|---|---|
| 発行日 | 2014-03-31 |
| 出版物タイトル | 岡山大学文学部プロジェクト研究報告書 |
| 巻 | 21巻 |
| 資料タイプ | 研究報告書 |
| 著者 | 渡邊 佳成| |
|---|---|
| 発行日 | 2015-03-31 |
| 出版物タイトル | 岡山大学文学部プロジェクト研究報告書 |
| 巻 | 22-2巻 |
| 資料タイプ | 研究報告書 |
| 著者 | 鐸木 道剛| |
|---|---|
| 発行日 | 2015-03-31 |
| 出版物タイトル | 岡山大学文学部プロジェクト研究報告書 |
| 巻 | 22-2巻 |
| 資料タイプ | 研究報告書 |
| 著者 | 遊佐 徹| |
|---|---|
| 発行日 | 2015-03-31 |
| 出版物タイトル | 岡山大学文学部プロジェクト研究報告書 |
| 巻 | 22-2巻 |
| 資料タイプ | 研究報告書 |
| 著者 | 花谷 正| Ito, Kasumi| |
|---|---|
| 発行日 | 2014-04 |
| 出版物タイトル | Heterocycles |
| 巻 | 88巻 |
| 号 | 2号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 岡山実験動物研究会| |
|---|---|
| 発行日 | 2015-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 31巻 |
| 資料タイプ | その他 |
| 著者 | 岡山実験動物研究会| |
|---|---|
| 発行日 | 2015-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 31巻 |
| 資料タイプ | その他 |
| 発行日 | 2015-04 |
|---|---|
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 31巻 |
| 資料タイプ | その他 |
| 著者 | 中尾 知代| |
|---|---|
| 発行日 | 1994-09 |
| 出版物タイトル | 岡山大学教養部紀要 |
| 巻 | 35巻 |
| 資料タイプ | 紀要論文 |
| フルテキストURL | K0005181_abstract_review.pdf K0005181_fulltext.pdf |
|---|---|
| 著者 | 韓 亮| |
| 発行日 | 2015-03-25 |
| 資料タイプ | 学位論文 |
| 学位授与番号 | 甲第5181号 |
| 学位授与年月日 | 2015-03-25 |
| 学位・専攻分野 | 博士（経済学） |
| 授与大学 | 岡山大学 |
| 言語 | 日本語 |
| 著者 | 畠中 香織| |
|---|---|
| 発行日 | 2015-03-25 |
| 出版物タイトル | |
| 資料タイプ | 学位論文 |