検索結果 19474 件
| JaLCDOI | 10.18926/52194 |
|---|---|
| タイトル（別表記） | Teaching a writing web class based on reflective questionnaires |
| フルテキストURL | bhe_009_101_110.pdf |
| 著者 | 大年 順子| |
| 抄録 | 本稿は平成25年度前期の「総合英語３」（ライティング）において, Web Class を利用したライティング授業を報告するものである。Web Classは岡山大学教育開発センターIT活用教育専門委員会・e-Learning 支援室が提供する基盤システムであり，本稿の実践クラスでは，おもに課題のやりとり，教員からのフィードバック，およびピアレビューなどがもちいられた。学期末に実施した振り返りアンケートからは，上級レベルの学生は「ピアレビュー」に，初級レベルの学生は「教員からのコメントフィードバック」にWeb Class の機能としての効果を認識していることがわかった。Web Classの利用は英語ライティング授業のアクティビティーの選択肢を広げることになると思われるが，学生のレベルや指導の目的を考慮したうえで，利用が求められることもあらためて確認された。 |
| キーワード | Web Class ライティング フィードバック ピアレビュー 振り返りアン ケート |
| 出版物タイトル | 大学教育研究紀要 |
| 発行日 | 2013-12-30 |
| 巻 | 9巻 |
| 開始ページ | 101 |
| 終了ページ | 110 |
| ISSN | 1881-5952 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005394616 |
| JaLCDOI | 10.18926/52189 |
|---|---|
| フルテキストURL | bhe_009_043_050.pdf |
| 著者 | Yoshida, Hiromi| |
| 抄録 | The purpose of this study is to examine a ‘popular’ tutor’s beliefs on feedback and her regular tutee’s receptivity toward the feedback in order to investigate factors involved in giving ‘good’ feedback within intercultural settings. The data was gathered by interviewing a pair of L1 tutor and L2 tutee and observing their tutorial sessions. The results revealed the importance of three points: building a ‘safe house’ for both the tutor and the tutee, respecting the tutee’s ‘writer’s identity,’ and using praise in an appropriate way. This research was conducted at a writing center; however, the findings offer important insights into feedback that are applicable to language teachers in multicultural and multilingual settings as well. |
| キーワード | interpersonal feedback academic writing writing center |
| 出版物タイトル | 大学教育研究紀要 |
| 発行日 | 2013-12-30 |
| 巻 | 9巻 |
| 開始ページ | 43 |
| 終了ページ | 50 |
| ISSN | 1881-5952 |
| 言語 | 英語 |
| 論文のバージョン | publisher |
| NAID | 120005394611 |
| JaLCDOI | 10.18926/52187 |
|---|---|
| タイトル（別表記） | Ａ review of the 2013 preparatory language（Chinese/Korean）training in the CAMPUS Asia program |
| フルテキストURL | bhe_009_017_026.pdf |
| 著者 | 大林 純子| |
| 抄録 | キャンパス・アジアでは長期派遣学生に対して語学（中国語あるいは韓国語、および英語）を中心とする「派遣前研修」を実施している。2013年度春期学生派遣に際して、前年度の研修内容を改良し、派遣前研修プログラムを実施した。改良の要点は、１）派遣学生の決定から渡航までの継続的最長期間を利用すること、２）チューター制度を活用し、グループ講義・対面学習（チューター）・自習支援という複数の学習機会を組み合わせた点である。派遣前研修は、短期間ではあるが、留学経験の乏しい学生にとって、実質的・心理的準備を支援する重要な役割を果たすことが成果として確認された。本研修プログラムの一定の成果と課題は、今後増加していくと考えられる派遣留学プログラムの充実化を図るに際して共有できるものであると考える。 |
| キーワード | 留学生派遣 外国語学習 派遣前研修 |
| 出版物タイトル | 大学教育研究紀要 |
| 発行日 | 2013-12-30 |
| 巻 | 9巻 |
| 開始ページ | 17 |
| 終了ページ | 26 |
| ISSN | 1881-5952 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005394609 |
| JaLCDOI | 10.18926/52186 |
|---|---|
| タイトル（別表記） | A Review of the Activities of the International Student Support Volunteer Group， WAWA： A Summarization of Its Twenty Year History |
| フルテキストURL | bhe_009_001_016.pdf |
| 著者 | 岡 益己| 安藤 佐和子| |
| 抄録 | 留学生支援ボランティア・WAWA は1994年に設立され、2002年には留学生センターの公認団体となり、2009年には念願の独立した活動拠点を手に入れた。WAWA 設立20年の節目に当たって、これまでのWAWA の活動の歴史を振り返ってみたい。（１）新入留学生の受入れ支援、（２）チュートリアル・サービス、（３）留学生家族のための日本語教室、（４）異文化交流イベントがWAWA の活動の４本柱であるが、学内外の環境変化の影響を受けて（１）は中止に、（２）は大幅縮小という状況に陥っている。また、ボランティア学生の気質の変化の影響により（３）も縮小せざるを得ず、（４）に関しては企画・運営力の低下が懸念される。こうした現状を踏まえ、設立21年目を迎えようとするWAWA のあり方について提言したい。 |
| キーワード | WAWA ボランティア 留学生 留学生相談室 |
| 出版物タイトル | 大学教育研究紀要 |
| 発行日 | 2013-12-30 |
| 巻 | 9巻 |
| 開始ページ | 1 |
| 終了ページ | 16 |
| ISSN | 1881-5952 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005394608 |
| JaLCDOI | 10.18926/bgeou/52180 |
|---|---|
| タイトル（別表記） | Consideration of a Choral Warm-up Ⅲ － from a Viewpoint of“ Mental Training” |
| フルテキストURL | bgeou_155_091_100.pdf |
| 著者 | 虫明 眞砂子| 黒井 かおり| |
| 抄録 | 歌唱と心技体のバランスの関係について，学生を対象に実施したメンタルトレーニングを取り入れた７日間の練習の間に行ったアンケート調査結果の分析をもとに考察した。その結果，以下の傾向が見られた。①全体的に，演奏本番に向かって，心技体のバランスを取り，良い状態にしていこうとする傾向にあること，②心技体のバランスがとれていない学生は，マイナス面の分野を大きく改善しようとする傾向にあること。③演奏経験の長い学年は，経験の短い学生に比べて，心技体の中ではメンタル面の数値が一番高く，常に気持ちをアップさせて技術面を伸ばそうとする傾向があること。よって，演奏経験の少ないものや歌唱に苦手意識がある学生に対して，心身のリラックスを促し，自信を持たせることが演奏能力向上に有効であり，演奏経験のある学生にとっても，技術面の伸張に繋がることが示唆された。 |
| キーワード | ウォームアップ 合唱 歌唱 心技体 バランス |
| 出版物タイトル | 岡山大学大学院教育学研究科研究集録 |
| 発行日 | 2014-02-25 |
| 巻 | 155巻 |
| 開始ページ | 91 |
| 終了ページ | 100 |
| ISSN | 1883-2423 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005394605 |
| JaLCDOI | 10.18926/bgeou/52178 |
|---|---|
| タイトル（別表記） | Physics Education at the Vocational Education Schools in Bavaria, a State of Germany |
| フルテキストURL | bgeou_155_067_078.pdf |
| 著者 | 田中 賢二| 田中 啓太| |
| 抄録 | ドイツ・バイエルン邦の職業教育諸学校に焦点を当て, いわば学校教育法，同施行規則，学習指導要領などを手がかりにし, 普通教育諸学校との対比などから物理教育を整理してきた。学校は，中等教育段階が分岐するフォーク型の普通教育諸学校と中等教育段階に属する多様な職業教育諸学校などに，峻別されている。中等教育段階に属する普通教育諸学校には教科物理があるが，職業教育諸学校ではなかったり，多くの授業時間数が配当されているなど多様であり，教科物理がある職業教育諸学校の学校種・科などでも，熱，原子，光，天文などを扱わないという偏りがあった。 |
| キーワード | ドイツ バイエルン邦 職業教育諸学校 物理教育 学習指導要領 |
| 出版物タイトル | 岡山大学大学院教育学研究科研究集録 |
| 発行日 | 2014-02-25 |
| 巻 | 155巻 |
| 開始ページ | 67 |
| 終了ページ | 78 |
| ISSN | 1883-2423 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005394603 |
| JaLCDOI | 10.18926/bgeou/52177 |
|---|---|
| タイトル（別表記） | The Discourse of Darwinism in Felix Holt, the Radical |
| フルテキストURL | bgeou_155_057_066.pdf |
| 著者 | 福永 信哲| |
| 抄録 | The present paper focuses attention on an influence of Darwinism as seen in the discourse of Felix Holt, the Radical. True George Eliot’s early and middle-period novels show signs of a vision of Natural History with its emphasis on scientific observation of the natural world. But as the impact of The Origin of Species (1859) sent a shock wave among the intellectual circle across Europe, she became growingly aware of its farreaching implications. Inevitably Eliot’s novelistic discourse has become permeated with the evolutionary outlook and terminology. Felix Holt marks a turning point in the sense that it is structurally conceived by the method of experimental science, and is clothed in its phraseology. We see how the writer’s moral and religious vision finds itself subtly reconciled with scientific world view. |
| キーワード | 進化 有機的生命 ネメシス 罪 仮説・検証 |
| 出版物タイトル | 岡山大学大学院教育学研究科研究集録 |
| 発行日 | 2014-02-25 |
| 巻 | 155巻 |
| 開始ページ | 57 |
| 終了ページ | 66 |
| ISSN | 1883-2423 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005394602 |
| JaLCDOI | 10.18926/bgeou/52175 |
|---|---|
| タイトル（別表記） | A Study of the Post-War History of Teaching Writing in Japan |
| フルテキストURL | bgeou_155_041_047.pdf |
| 著者 | 菅原 稔| |
| キーワード | 戦後 作文 綴り方 第１回作文教育全国協議会 中津川大会 |
| 出版物タイトル | 岡山大学大学院教育学研究科研究集録 |
| 発行日 | 2014-02-25 |
| 巻 | 155巻 |
| 開始ページ | 41 |
| 終了ページ | 47 |
| ISSN | 1883-2423 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005394600 |
| JaLCDOI | 10.18926/bgeou/52171 |
|---|---|
| タイトル（別表記） | An Attempt to Construct a Scale on School Support Systems for Pupils and Students: Focusing on Special Collaboration and Homogeneity Cooperation |
| フルテキストURL | bgeou_155_001_012.pdf |
| 著者 | 荊木 まき子| 淵上 克義| 古市 裕一| |
| 抄録 | 学校内におけるスクールカウンセラー（以下SC）と教員の協働には幾多の困難があることが指摘されてきた。荊木･森田（投稿中）はSC を対象とした面接調査から，学校内における協働を専門性協働（SC と教員との協働）と均質性協働（教員間の協働）とに区分し， 協働のあり方が異なることを明らかにした。本研究では，この知見に基づいて児童･生徒への支援体制に関する尺度の構成を目指し，教員・教員経験者９名，管理職・管理職経験者６名に面接調査等を行った。回答結果をKJ 法に基づき分析した結果，教員とSC の専門性の 理解不足に対して，自治体や管理職の働きかけにより，協働可能な環境が設定されること，また，教育相談の位置づけが生徒指導や進路指導と比較して曖昧で不安定であることが示された。これらの結果により，管理職に焦点を合わせた質問紙構成や，質問項目に具体性を持たせることの必要性などが明らかにされた。 |
| キーワード | school counselor teacher scale construction homogeneity cooperation special collaboration |
| 出版物タイトル | 岡山大学大学院教育学研究科研究集録 |
| 発行日 | 2014-02-25 |
| 巻 | 155巻 |
| 開始ページ | 1 |
| 終了ページ | 12 |
| ISSN | 1883-2423 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120005394596 |
| JaLCDOI | 10.18926/ESR/52167 |
|---|---|
| タイトル（別表記） | Preliminary analyses on the climatological features of precipitation characteristics and large-scale atmospheric fields on the heavy rainfall days in the eastern part of Japan during the mature stage of the Baiu season |
| フルテキストURL | esr_020_1_025_034.pdf |
| 著者 | 松本 健吾| 加藤 内藏進| 大谷 和男| |
| 抄録 | Rainfall characteristics and large-scale atmospheric fields on the “heavy rainfall days” (with more than 50 mm/day) in the mature stage of the Baiu season (16 June ~ 15 July) at Tokyo in the eastern part of the Japan Islands were examined, based on the daily and the hourly precipitation data from 1971 to 2010. Appearance frequency of the “heavy rainfall days” at Tokyo attained only about 1/3 of that at Nagasaki in the western Japan. Furthermore, it is noted that about half of the “heavy rainfall days” at Tokyo were related to the typhoon. In detail, about half of the typhoon cases were associated with the direct approach of a typhoon (referred to as Pattern A, hereafter), the other half corresponded to the situation when the Baiu front also stagnated around Kanto District with a typhoon to the southwest of Kanto (Pattern B). Although the contribution of the intense rainfall with more than 10 mm/h to the total precipitation was large in Pattern A, that with less than 10 mm/h was dominant in Patterns B and C (Pattern C: meso-α-scale cyclone on the Baiu front approaching to the Kanto District). It is noted that about half of the “heavy rainfall days” corresponded to these pattern. In other words, unlike the localized torrential rain in western Japan, the “heavy rainfall days” due to the duration of “not-so-intense-rain” appeared rather frequently in the eastern part of Japan even in the Baiu season. In both Patterns B and C, relatively strong low-level southerly wind associated with the disturbance (a typhoon or a meso-α-scale cyclone) invades into the baroclinic zone in the basic field sustained as the sowthwestern edge of the cool Okhotsk air mass. It is interesting that the “heavy rainfall days” there due to the contribution of the persistent “not-so-intense-rain” occur just in such situation. |
| キーワード | rainfall characteristics in eastern Japan heavy rainfall in eastern Japan in Baiu season rainfall climatology |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2013-12-27 |
| 巻 | 20巻 |
| 号 | 1号 |
| 開始ページ | 25 |
| 終了ページ | 34 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2013 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120005394595 |
| JaLCDOI | 10.18926/ESR/52166 |
|---|---|
| タイトル（別表記） | A case study on the rainfall distribution over the Japan Islands associated with the approach of Ty0423 in late October (Comparison with that for Ty0418) |
| フルテキストURL | esr_020_1_013_024_rev.pdf |
| 著者 | 佐竹 愛| 加藤 内藏進| 盛 宣誠| 合田 泰弘| 池田 祥一郎| 塚本 修| |
| 抄録 | Rainfall distribution in the Japan Islands associated with the approach of Typhoon No.23 around 20 October 2004 (referred to Ty0423, hereafter) showed considerably different features from those in late summer of this year. The present study examined the detailed rainfall features around the Japan Islands brought by Ty0423 and the atmospheric processes based on the operational observation data by the Japan Meteorological Agency (JMA), comparing with those in association with Ty0418 around 7 September 2004. During the stage when Ty0423 was approaching or landing on the western part of the Japan Islands, the areal mean precipitation from Kyushu to Kanto District attained much larger than that for Ty0418, with wider extension of the area with the large amount of precipitation. It is interesting that, although the intense rainfall was observed only at the upstream side of the mountain range from Kyushu to Honshu District for Ty0418 except for the area near its center, strong rainfall with 10~30 mm/h persisted in wider regions from the western to the eastern part of the Japan Islands, resulting in the considerably large total rainfall for Ty0423. As for the case for Ty0423, the surface front with stable frontal surface was located just to the east of the Ty0423 center just before its landing at the Japan Islands. Thus, the huge moisture inflow mainly in the eastern region from the typhoon center seems to be redistributed widely over the Japan Islands area associated with the large-scale convergence around the stable frontal surface. In late October, the colder air associated with the high pressure system in the eastern Siberia can cover the northern part of the Japan Sea area as the seasonal march. Such basic field might be favorable for sustaining the synoptic-scale front just around the southern coast of the Japan Islands, even when the strong southerly wind invades associated with the typhoon approach there. |
| キーワード | Ty0423 Ty0418 rainfall in Japan associated with a typhoon in mid-autumn effects of a typhoon on the synoptic climatology in Japan in October |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2013-12-27 |
| 巻 | 20巻 |
| 号 | 1号 |
| 開始ページ | 13 |
| 終了ページ | 24 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2013 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120005394594 |
| JaLCDOI | 10.18926/ESR/52165 |
|---|---|
| タイトル（別表記） | On Periploma mitsuganoense Araki (Bivalvia: Mollusca) from the Miocene Bihoku Group in Niimi City, Okayama Prefecture, southwest Japan ―with special reference to it’s paleogeographic significance― |
| フルテキストURL | esr_020_1_007_011.pdf |
| 著者 | 田口 栄次| 岸本 眞五| 鈴木 茂之| |
| 抄録 | In this paper, we deal with re-description of Periploma mitsuganoense Araki and it’s morphological variation and significance of the molluscan fauna of it from the Miocene Bihoku Group in Niimi City, Okayama Prefecture, Southwest Japan. Moreover, the paleogeographic significance of this species is analyzed. The obtained results are summarized as follows: 1. The morphological variation of Periploma mitsuganoense Araki has a wide range on the basis of the analysis of the morphological outline. 2. The occurrence of P. mitsuganoense Araki from the Pectinid fauna is the first record in the West Setouchi Geological Province. 3. It is presumable that P. mitsuganoense Araki is an endemic species in the First Setouchi Geological Province from a view point of it’s spatial distribution. |
| キーワード | Periploma mitsuganoense Araki Mollusca Miocene Bihoku Group morphological variation paleogeographic significance |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2013-12-27 |
| 巻 | 20巻 |
| 号 | 1号 |
| 開始ページ | 7 |
| 終了ページ | 11 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2013 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120005394593 |
| JaLCDOI | 10.18926/ESR/52164 |
|---|---|
| タイトル（別表記） | Debris avalanche occurred in Kitamura area, Kurashiki City, Okayama Prefecture |
| フルテキストURL | esr_020_1_001_006.pdf |
| 著者 | 木村 裕貴| 鈴木 茂之| |
| 抄録 | The debris avalanche occurred in Kitamura area, Kurashiki City, Okayama Prefecture caused by the hard rain of Typhoon 12 of September, 2011. Furthermore, 11 small landslides occurred in the study area. In this area, the altitude of mountainous are not so high (150m to 250m) and the amount of precipitation which producted the debris avalanche was not very serious quantity with 230mm. However the debris avalanche occurred. One private house collapsed, and the first floor part of the Kitamura Elementary School was buried due to the debris flow. The purpose of this study is to examine causes of the debris avalanche disaster occurred in Kitamura area using applied geological technique. The length of the debris avalanche scar is about 250m, and alluvial fan is formed as a debris slope. The ground is composed of weathered granite and the bottom of the valley was filled by soils derived from disintegrated granite. There are three small landslides as head scarps with steep slopes at approximately 30°-35°. The debris avalanche was inferred to have started as a shallow soil slip at the head by rainfall. 3 major causes are inferred which originated the debris avalanche in the study area; steep slope, ground composed of weathered granite, existence of sandy soil which occupied at the bottom of valley. |
| キーワード | debris avalanche steep slope weathered granite |
| 出版物タイトル | Okayama University Earth Science Report |
| 発行日 | 2013-12-27 |
| 巻 | 20巻 |
| 号 | 1号 |
| 開始ページ | 1 |
| 終了ページ | 6 |
| ISSN | 1340-7414 |
| 言語 | 日本語 |
| 著作権者 | © 2013 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| 論文のバージョン | publisher |
| NAID | 120005394592 |
| JaLCDOI | 10.18926/AMO/52145 |
|---|---|
| フルテキストURL | 68_1_53.pdf |
| 著者 | Terasaka, Tomohiro| Ueta, Eijiro| Ebara, Hirotaka| Waseda, Koichi| Hanayama, Yoshihisa| Takaki, Akinobu| Kawabata, Tomoko| Sugiyama, Hitoshi| Hidan, Ko| Otsuka, Fumio| |
| 抄録 | A 64-year-old man suffering polyarthralgia and bone pain was referred to our hospital. Renal dysfunction, hypophosphatemia and increased levels of bone alkaline phosphatase were found. The patientʼs serum creatinine level had gradually increased after the initiation of adefovir dipivoxil administration for hepatitis B. In agreement with multifocal uptakes of bone scintigraphy, iliac bone biopsy revealed an abnormal increase in osteoid tissues. Reducing the dose of adefovir and initiating the administration of eldecalcitol were effective for reducing proteinuria and glucosuria, and for ameliorating bone pain with an increase in serum phosphate level. This case first showed a clinical course of hypophosphatemic osteomalacia caused by secondary Fanconiʼs syndrome for 8 years after adefovir administration. Early diagnosis is important for the reversibility of bone damage and for a better renal prognosis. |
| キーワード | adefovir dipivoxil (ADV) eldecalcitol Fanconi's syndrome hypophosphatemia osteomalacia |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-02 |
| 巻 | 68巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 53 |
| 終了ページ | 56 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24553490 |
| JaLCDOI | 10.18926/AMO/52144 |
|---|---|
| フルテキストURL | 68_1_47.pdf |
| 著者 | Ishikawa, Tsutomu| Araki, Motoo| Hirata, Takeshi| Watanabe, Masami| Ebara, Shin| Watanabe, Toyohiko| Nasu, Yasutomo| Kumon, Hiromi| |
| 抄録 | We report 3 patients with the rare complication of an indwelling urethral catheter misdirected into the ureter. This is the largest series to date. Patients were referred to us for a variety of reasons following exchange of their chronic indwelling urinary catheters. CT in all cases demonstrated the urinary catheters residing in the left ureter. The ages of the patients were 37, 67 and 81 years old. All patients suffered from neurogenic bladder. Two patients were female, one was male, and 2 of the 3 had a sensory disorder inhibiting their pain response. The catheters were replaced with open-end Foley catheters. Extensive follow-up CT scans were obtained in one case, demonstrating improvement of hydronephrosis and no evidence of ureteral stenosis. Cystoscopy in this patient demonstrated normally positioned and functioning ureteral orifices. Although the placement of an indwelling urethral catheter is a comparatively safe procedure, one must keep in mind that this complication can occur, particularly in female patients with neurogenic bladder. CT without contrast is a noninvasive, definitive diagnostic tool. |
| キーワード | complication indwelling urethral catheter imaging computed tomography ureter |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-02 |
| 巻 | 68巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 47 |
| 終了ページ | 51 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24553489 |
| Web of Science KeyUT | 000331592800008 |
| JaLCDOI | 10.18926/AMO/52143 |
|---|---|
| フルテキストURL | 68_1_43.pdf |
| 著者 | Miyatake, Nobuyuki| Shikata, Kenichi| Makino, Hirofumi| Numata, Takeyuki| |
| 抄録 | The link between lifestyle modification and changes in both proteinuria and estimated glomerular filtration rates (eGFRs) was evaluated in Japanese subjects with proteinuria who were not taking medications. We used data from 51 men (35.8±10.0 years) and 74 women (38.0±11.0 years) with proteinuria at baseline and a 1-year follow up. eGFR was defined by a new equation developed specifically for Japanese subjects. Subjects were given advice for dietary and lifestyle improvement at the initial appointment. At the 1-year follow up, eGFR was increased in both sexes, but not at significant levels. (men:p＝0.7709, women:p＝0.2180). Proteinuria was also improved in many subjects. A decrease in proteinuria may be associated with improving eGFR in Japanese. |
| キーワード | proteinuria estimated glomerular filtration rate (eGFR) lifestyle modification |
| Amo Type | Short Communication |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-02 |
| 巻 | 68巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 43 |
| 終了ページ | 46 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24553488 |
| Web of Science KeyUT | 000331592800007 |
| JaLCDOI | 10.18926/AMO/52142 |
|---|---|
| フルテキストURL | 68_1_35.pdf |
| 著者 | Araki, Motoo| Jeong, Wooju| Park, Sung Yul| Lee, Young Hoon| Nasu, Yasutomo| Kumon, Hiromi| Hong, Sung Joon| Rha, Koon Ho| |
| 抄録 | The purpose of this study was to compare the positive surgical margin (PSM) rates of 2 techniques of robot-assisted radical prostatectomy (RARP) for pT2 (localized) prostate cancer. A retrospective analysis was conducted of 361 RARP cases, performed from May 2005 to September 2008 by a single surgeon (KHR) at our institution (Yonsei University College of Medicine). In the conventional technique, the bladder neck was transected first. In the modified ultradissection, the lateral border of the bladder neck was dissected and then the bladder neck was transected while the detrusor muscle of the bladder was well visualized. Perioperative characteristics and outcomes and PSM rates were analyzed retrospectively for pT2 patients (n＝217), focusing on a comparison of those undergoing conventional (n＝113) and modified ultradissection (n＝104) techniques. There was no difference between the conventional and modified ultradissection group in mean age, BMI, PSA, prostate volume, biopsy Gleason score, and DʼAmico prognostic criteria distributions. The mean operative time was shorter (p＜0.001) and the estimated blood loss was less (p＜0.01) in the modified ultradissection group. The PSM rate for the bladder neck was significantly reduced by modified ultradissection, from 6.2% to 0% (p＜0.05). In conclusion, modified ultradissection reduces the PSM rate for the bladder neck. |
| キーワード | robot-assisted radical prostatectomy prostate cancer surgery surgical margin technique |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-02 |
| 巻 | 68巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 35 |
| 終了ページ | 41 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24553487 |
| Web of Science KeyUT | 000331592800006 |
| JaLCDOI | 10.18926/AMO/52141 |
|---|---|
| フルテキストURL | 68_1_27.pdf |
| 著者 | Yoshida, Masao| Ishikawa, Mamoru| Karita, Kanae| Kokaze, Akatsuki| Harada, Matsuko| Take, Shinichiro| Ohno, Hideki| |
| 抄録 | To clarify whether high blood pressure (BP) and high body mass index (BMI) are associated with elevated intraocular pressure (IOP), a cross-sectional and longitudinal study was conducted. This epidemiological study analyzed health examination data obtained between 2001 and 2005 from 896 Japanese individuals (aged 32-79 years) who had not undergone any ocular surgery or medical treatment for hypertension, ocular hypertension, or glaucoma. Multiple-regression analysis of our cross-sectional data showed that systolic and diastolic BP (SBP and DBP) and BMI had significant and near-significant positive associations with IOP in men (p＜0.05) and women (p＜0.1). Our longitudinal study from analyses of covariance found that the adjusted mean level of changes in IOP tended to increase with increased levels of SBP, DBP, and BMI in men (p＜0.1). In women also, changes in SBP and BMI tended to be positively related with that of IOP (p＜0.1). The results of this study suggested that BP and BMI were positively associated with IOP in middle-aged and older Japanese. Therefore, management of BP and improvement of obesity might be especially important to Japanese patients with open-angle glaucoma or ocular hypertension as they have a higher incidence of normal-tension glaucoma than Europeans and Americans. |
| キーワード | intraocular pressure blood pressure body mass index epidemiology glaucoma |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-02 |
| 巻 | 68巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 27 |
| 終了ページ | 34 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24553486 |
| Web of Science KeyUT | 000331592800005 |
| JaLCDOI | 10.18926/AMO/52140 |
|---|---|
| フルテキストURL | 68_1_23.pdf |
| 著者 | Ueno, Tsuyoshi| Toyooka, Shinichi| Fukazawa, Takuya| Kubo, Takafumi| Soh, Junichi| Asano, Hiroaki| Muraoka, Takayuki| Tanaka, Norimitsu| Maki, Yuho| Shien, Kazuhiko| Furukawa, Masashi| Sakaguchi, Masakiyo| Yamamoto, Hiromasa| Tsukuda, Kazunori| Miyoshi, Shinichiro| |
| 抄録 | The microRNA-34s (miR-34s) have p53 response elements in their 5ʼ-flanking regions and demonstrate tumor-suppressive functions. In malignant pleural mesothelioma (MPM), we previously reported that expression of miR-34b and miR-34c (miR-34b/c) was frequently downregulated by methylation in MPM cell lines and primary tumors. The forced overexpression of miR-34b/c showed significant antitumor effects with the induction of apoptosis in MPM cells. In this study, we examined the in vivo antitumor effects of miR-34b/c using adenovirus vector on MPM. We subcutaneously transplanted NCI-H290, a human MPM cell line, into BALB/C mice and injected adenovirus vector expressing miR-34b/c, luciferase driven by the cytomegalovirus promoter (Ad-miR-34b/c or Ad-Luc), or PBS control into tumors over 5mm in diameter. A statistically significant growth inhibition of the tumor volume was observed in the Ad-miR-34b/c group from day 6 onward compared to the Ad-Luc group. The inhibition rate of Ad-miR-34b/c, compared to the tumor volume treated with Ad-Luc, was 58.6% on day 10 and 54.7% on day13. Our results indicate that adenovirus-mediated miR-34b/c gene therapy could be useful for the clinical treatment of MPM. |
| キーワード | mesothelioma microRNA microRNA-34b/c p53 |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-02 |
| 巻 | 68巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 23 |
| 終了ページ | 26 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24553485 |
| Web of Science KeyUT | 000331592800004 |
| JaLCDOI | 10.18926/AMO/52139 |
|---|---|
| フルテキストURL | 68_1_17.pdf |
| 著者 | Moritou, Yuki| Ikeda, Fusao| Iwasaki, Yoshiaki| Baba, Nobuyuki| Takaguchi, Kouichi| Senoh, Tomonori| Nagano, Takuya| Takeuchi, Yasuto| Yasunaka, Tetsuya| Ohnishi, Hideki| Miyake, Yasuhiro| Takaki, Akinobu| Nouso, Kazuhiro| Yamamoto, Kazuhide| |
| 抄録 | The impact of hepatic steatosis on interferon therapy for patients with chronic hepatitis C (CHC) has been associated with single-nucleotide polymorphisms (SNP) of IL28B, patatin-like phospholipase domain-containing protein 3 (PNPLA3), and low-density lipoprotein (LDL) receptor. Whether this holds true for Japanese patients, however, remains unresolved. The present study prospectively enrolled 226 Japanese patients with CHC, and investigated the impact of hepatic steatosis and its related SNPs, including rs8099917 of IL28B, rs738409 of PNPLA3, and rs14158 of LDL receptor, on outcomes of peg-interferon and ribavirin therapy. In multivariate logistic regression analysis, significant factors affecting the severity of hepatic steatosis were high body mass index and the minor alleles of IL28B SNP (p＝0.020 and 0.039, respectively). The risk alleles of PNPLA3 SNP also showed weak association (p＝0.059). Severe steatosis and the minor alleles of IL28B SNP were significantly associated with null or partial virological response in patients with HCV genotype 1, as were female gender, and low LDL cholesterol (p＝0.049, and ＜0.001, respectively). The SNP genotype of PNPLA3 and LDL receptor did not have a significant impact on therapeutic outcomes. With respect to the SNP sites examined, the SNP of PNPLA3 has a weak association with severe hepatic steatosis, but not with the outcome of interferon therapy. |
| キーワード | hepatic steatosis genetic polymorphism interferon HCV |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-02 |
| 巻 | 68巻 |
| 号 | 1号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 17 |
| 終了ページ | 22 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24553484 |
| Web of Science KeyUT | 000331592800003 |