検索条件

閉じる

検索結果 1299 件

著者 Shinga-Ishihara, Chikako| Nakai, Yukie| Milgrom, Peter| Murakami, Kaori| Matsumoto-Nakano, Michiyo|
発行日 2014-01-02
出版物タイトル BMC Oral Health
巻 14巻
資料タイプ 学術雑誌論文
著者 Fujimori, Shoichi| Kim, Young Wook| Koh, Sung-Eun| Rossman, Wayne| Shin, Heayong| Umehara, Masaaki| Yamada, Kotaro| Yang, Seong-Deog|
発行日 2015-01
出版物タイトル Mathematical Journal of Okayama University
巻 57巻
号 1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/mjou/53048
タイトル(別表記) A case of microscopic low-grade appendiceal mucinous neoplasm complicated with appendicitis resected by reduced-port laparoscopic surgery
フルテキストURL 126_223.pdf
著者 鈴木 宏光| 木村 紘爾| 木下 茂喜| 岡野 和雄|
抄録 Appendicitis is a benign disease for which surgical treatment is widely provided. The complication of neoplastic lesions may be discovered only after resection. However, in some cases, specimens are not submitted to histopathological examination in Japan because of an extreme deficiency of pathologists. We report our experience with one patient who experienced the complication of latent low-grade appendiceal mucinous neoplasm (LAMN) after surgery for appendicitis. Our patient was an 85-year-old woman. Conservative treatment failed to relieve fever and lower abdominal pain and it was decided to treat her surgically. Abdominal computed tomography (CT) showed appendicitis with severe inflammation and suspected adhesion. We decided to explore the abdominal cavity using a reduced-port laparoscopic approach. We found no mucous debouchment or clear tumors in the specimen. Histopathological findings indicated the coexistence of appendicitis and LAMN. At one year and a half after surgery, there was no evidence of the development of pseudomyxoma peritonei. In appendectomy, it is thought that careful perioperative treatment and a postoperative pathological search are important when there are no preoperative findings suggesting a neoplastic lesion.
キーワード 虫垂炎(appendicitis) 減孔式腹腔鏡手術(reduced-port laparoscopic surgery) 虫垂粘液嚢胞腺腫(low-grade appendiceal mucinous neoplasm (LAMN)) 腹膜偽粘液腫(pseudomyxoma peritonei) 腹腔鏡下虫垂切除術(laparoscopic appendectomy)
出版物タイトル 岡山医学会雑誌
発行日 2014-12-01
巻 126巻
号 3号
開始ページ 223
終了ページ 226
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.223
NAID 130004903238
タイトル(別表記) Giant rectal gastrointestinal stromal tumor successfully resected by abdominoperineal resection combined with posterior vaginal wall resection
フルテキストURL 126_217.pdf
著者 岩川 和秀| 西江 学| 徳永 尚之| 宮宗 秀明| 岩垣 博巳|
抄録 We report a case of giant rectal gastrointestinal stromal tumor (GIST) successfully resected by abdominoperineal resection combined with posterior vaginal wall resection. Our patient was a 79-year-old woman had been diagnosed as having von Recklinghausen disease at the age of 30 years. In 2006, a computed tomography (CT) scan revealed a tumor originating from the posterior wall of the rectum. In June 2010, she was admitted to our hospital with the chief complaint of bloody stool. A CT scan revealed a giant tumor that had increased to 9cm in size. Colonoscopy demonstrated a submucosal tumor, which was subsequently diagnosed by biopsy as a GIST. Due to the patient's continuous bleeding and abdominal pain, an emergent abdominoperineal resection was performed at that time. The tumor, which measured 8×9cm, was immunohistochemically positive for c-kit and CD34. Concomitant resection of the posterior wall of the vagina via the perineal approach provided a wide area to expose the tumor for a safe operation. The patient has been well with no sign of recurrence since the operation. This procedure is recommended as a useful approach for giant rectal GISTs or rectal cancer with invasion of the posterior pelvic wall.
キーワード 巨大直腸GIST(giant rectal GIST) 腹会陰式直腸切断術(abdominoperineal resection)
出版物タイトル 岡山医学会雑誌
発行日 2014-12-01
巻 126巻
号 3号
開始ページ 217
終了ページ 221
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.217
NAID 130004903245
タイトル(別表記) The 2013 Incentive Award of the Okayama Medical Association in General Medical Science (2013 Yuuki Prize)
フルテキストURL 126_187.pdf
著者 山本 寛斉|
抄録 受賞対象論文: Yamamoto H, Higasa K, Sakaguchi M, Shien K, Soh J, Ichimura K, Furukawa M, Hashida S, Tsukuda K, Takigawa N, Matsuo K, Kiura K, Miyoshi S, Matsuda F, Toyooka S:Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas. J Natl Cancer Inst (2014) 106, djt338
出版物タイトル 岡山医学会雑誌
発行日 2014-12-01
巻 126巻
号 3号
開始ページ 187
終了ページ 190
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.187
NAID 130004903235
著者 Nagataki, Hiroyuki| Nakano, Yoshiaki| Nobe, Midori| Tohyama, Tatsuya| Kanemune, Susumu|
発行日 2013-11
出版物タイトル Proceedings of 8th Workshop in Primary and Secondary Computing Education
資料タイプ 会議発表論文
著者 Nakayama, Kazunori| Nakao, Kazushi| Takatori, Yuji| Inoue, Junko| Kojo, Shoichirou| Akagi, Shigeru| Fukushima, Masaki| Wada, Jun| Makino, Hirofumi|
発行日 2013-12-18
出版物タイトル International Journal of Nephrology and Renovascular Disease
巻 7巻
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/52791
フルテキストURL 68_4_249.pdf
著者 Ogawara, Yuya| Tachibana, Tomoyasu| Orita, Yorihisa| Uchino, Kaori| Wani, Yoji| Nagahiro, Itaru| Matsuyama, Yuko| Abe, Iku| Fujisawa, Masayoshi| Nishizaki, Kazunori|
抄録 We describe an extremely rare case of tracheal stenosis caused by unnoticed microscopic fiber-like foreign bodies. A 66-year-old woman complained of dyspnea with inspiratory stridor. Magnifying electroendoscopy and computed tomography revealed stenosis involving the entire circumference of the tracheal lumen. Tracheotomy and biopsy were performed. Histologically, the lesion showed chronic inflammation with a deposition of fiber-like foreign bodies. The patient had no history of trauma or inhalation injury, but had undergone intratracheal intubation on 4 occasions. The lesion was incised using semiconductor laser photoresection, and the postoperative course was good. To the best of our knowledge, this represents the first report in the English literature of tracheal stenosis caused by unnoticed foreign bodies. The origin of these fiber-like foreign bodies remains unclear but might be related to chronic inflammation resulting from intratracheal intubations.
キーワード tracheal stenosis fibrous foreign body intubation tracheotomy laser
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2014-08
巻 68巻
号 4号
出版者 Okayama University Medical School
開始ページ 249
終了ページ 252
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 25145411
Web of Science KeyUT 000340687500007
タイトル(別表記) The origin of infra-slow oscillations of oxygenated hemoglobin observed in functional near-infrared spectroscopy
フルテキストURL 126_117.pdf
著者 所司 睦文| 上野 浩司| 久保 正子| 小田 真珠子| 平田 直也| 武本 梨佳| 衣笠 和孜| 岡本 基|
抄録 There is increasing interest in the intrinsic activity of the resting brain, especially the activity slower than 0.1Hz (i.e., low-frequency oscillations, or LFOs). To investigate the origin of LFOs observed in functional near-infrared spectroscopy (fNIRS), we recorded multichannel fNIRS and electroencephalography (EEG) from the frontal cortex of 11 healthy young volunteers in the resting state. Electrocardiography (ECG), electro-oculography and respiration were also measured. Synchronous oscillations of oxy-hemoglobin (oxy-Hb) around 1.0Hz were detected in all fNIRS channels, and their frequency was consistent with a peak frequency of ECG, suggesting the changes of cerebral blood flow due to heart beats. In addition, oxy-Hb oscillations around 0.1Hz (i.e., LFOs) appeared in the fNIRS. The channels where LFOs appeared differed among the subjects, and the LFOs appeared or disappeared even in the same fNIRS channels. The appearance of LFOs in fNIRS channels was significantly higher when the LFOs appeared on the EEG in the adjacent EEG electrodes compared to when LFOs did not appear on EEG. The amplitude and coherence (synchronicity) of the LFOs were increased by changing the subjects' position from dorsal to the sitting position in both fNIRS and EEG, and the coherence in particular was increased in the homologous fNIRS channels on the bilateral hemispheres. These results suggest that LFOs of oxy-Hb couple with resting-state EEG activity.
キーワード fNIRS EEG LFOs コヒーレンス解析(Coherence analysis) 連続ウェーブレット解析(continuous wavelet transforms)
出版物タイトル 岡山医学会雑誌
発行日 2014-08-01
巻 126巻
号 2号
開始ページ 117
終了ページ 126
ISSN 0030-1558
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.117
NAID 130004685262
JaLCDOI 10.18926/AMO/52659
フルテキストURL 68_3_177.pdf
著者 Mizuno, Shoma| Ota, Seisuke| Tanaka, Takehiro| Shiomi, Kohei| Matsumura, Tadashi| Kishimoto, Nobuyasu|
抄録 Primary tracheal malignant lymphoma is a rare disease;only 30 cases have been reported to date. A 73-year-old Japanese man with a history of asbestos exposure was undergoing biannual chest computed tomography (CT) twice a year as a routine procedure for those previously exposed to asbestos. He had been smoking since the age of 32. In September 2010, chest CT during this regular checkup revealed a polypoid lesion in his trachea and pleural plaques, which were suspected to be caused by asbestos. Bronchoscopy performed in October revealed a polypoid lesion with granules and nodules in the trachea. A diagnosis of non-Hodgkin lymphoma (NHL) and extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) was confirmed by histological analysis of the biopsy specimens. To our knowledge, this is the first case of primary tracheal lymphoma associated with a history of asbestos exposure. Several reports have documented no correlation between asbestos and malignant lymphoma. In addition, the correlation between smoking and NHL is weak. Although we cannot exclude the possibility of a simple coincidence of asbestos, smoking, and tracheal lymphoma, this case suggests that asbestos and smoking might have multiplicative effects in the development or progression of tracheal lymphoma.
キーワード bronchus-associated lymphoid tissue tracheal lymphoma regular checkup asbestos smoking
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2014-06
巻 68巻
号 3号
出版者 Okayama University Medical School
開始ページ 177
終了ページ 181
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24942797
Web of Science KeyUT 000337655600008
フルテキストURL Talanta_122_240–245.pdf
著者 Higashidani, Naoki| Kaneta, Takashi| Takeyasu, Nobuyuki| Motomizu, Shoji| Okibe, Naoko| Sasaki, Keiko|
キーワード Thermoacidophilic iron-oxidizing archaeon Acidianus brierleyi Arsenic Speciation Inductively coupled plasma–optical emission spectroscopy Flow injection pretreatment
発行日 2014-05
出版物タイトル Talanta
巻 122巻
出版者 Elsevier
開始ページ 240
終了ページ 245
ISSN 00399140
NCID AA00856594
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2014 Elsevier B.V. All rights reserved
論文のバージョン author
PubMed ID 24720990
DOI 10.1016/j.talanta.2014.01.057
Web of Science KeyUT 000335636700037
関連URL isVersionOf https://doi.org/10.1016/j.talanta.2014.01.057
JaLCDOI 10.18926/AMO/52403
フルテキストURL 68_2_63.pdf
著者 Fujii, Yasuyuki| Hoshino, Tyuji| Kumon, Hiromi|
抄録 Dickkopf (DKK) proteins interact with low-density lipoprotein receptor-related protein 5/6 (LRP5/6) to modulate WNT signaling. The interaction is mediated by a cysteine-rich domain (C2) in the DKK protein and β-propeller domains (PD) of LRP5/6. However, the third member of the DKK family (DKK3) does not bind to LRP5/6. To determine why DKK3 does not bind to the receptor domains, we performed a molecular modeling simulation study including homology modeling, protein-protein docking and molecular dynamics (MD). The computed affinities (ΔGbinding) between the C2 and PD models were consistent with the previously reported experimental results. The C2 model of DKK3 showed the lowest affinity for PD models. Multiple sequence alignment of C2 domains revealed that the DKK3 genes have a unique 7-amino-acid insertion (L249-E255 in human DKK3) and P258 in a finger loop 1 (FL1). Interestingly, the insertion sequence is evolutionally conserved. MD simulations of high-affinity complex models of C2 and PD showed that FL1 directly interacts with the PD models and stabilizes the complex models. We also built a 7-amino-acid-deletion/P258G mutant model of DKK3C2 and estimated its affinities for the PD models. The affinity for human LRP5PD2 was increased by the substitution (ΔGbinding=-48.9kcal/mol) and the affinity was compatible with that of high-affinity ligands. The results suggested that the lack of affinity between human DKK3 and human LRP5/6 results from: i) insertion of the 7 amino acids, and ii) P258 in human DKK3. The sequence differences thus suggest an explanation for this unique property of DKK3.
キーワード DKK3 molecular modeling protein-protein docking LRP5/6
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-04
巻 68巻
号 2号
出版者 Okayama University Medical School
開始ページ 63
終了ページ 78
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24743782
Web of Science KeyUT 000334652700002
タイトル(別表記) A case of colon lipoma presenting with intussusception
フルテキストURL 126_35.pdf
著者 二宮 卓之| 小島 康知| 原野 雅生| 大野 聡| 塩崎 滋弘| 二宮 基樹|
抄録  An 84-year-old man, who had been found to have a submucosal tumor in the ascending colon two years before, was admitted to our hospital for right lower quadrant abdominal pain and melena. An abdominal computed tomography (CT) scan showed intussusception in the ascending colon, resulting from a fat-density tumor. The intussusception was located by colonoscopy. Since the colonic tumor was enlarged in comparison with two years ago and had an ulcer at the top of the tumor, there was the possibility of malignancy and recurrence of intussusception. He underwent a laparoscopy-assisted right colectomy with lymph node dissection. Pathologically, the tumor of the ascending colon was a benign lipoma.
キーワード 結腸脂肪腫(lipoma of the colon) 腸重積(intussusception) 腹腔鏡下手術(laparoscopic surgery)
出版物タイトル 岡山医学会雑誌
発行日 2014-04-01
巻 126巻
号 1号
開始ページ 35
終了ページ 38
ISSN 0030-1558
関連URL http://www.okayama-u.ac.jp/user/oma/
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.35
タイトル(別表記) Metastatic breast cancer presenting as severe anemia, platelet reduction and abnormal cells in peripheral blood
フルテキストURL 126_31.pdf
著者 太田 誠介| 笠原 明宣| 水野 翔馬| 深津 遥香| 木下 修| 野口 敏生| 岸本 信康| 松村 正|
抄録  Worldwide, breast cancer accounts for 22.9% of all cancers excluding non-melanoma skin cancers in women. More than 80% of breast cancer cases are discovered when a woman discovers a lump that feels different from the rest of the breast tissue. We report the case of a 60-year-old woman who had been treated for one year at a psychiatric hospital for suspected schizophrenia, and was referred to our hospital on March 23, 2011 for consultation regarding complete blood count abnormalities: hemoglobin, 4.8g/㎗ ; Plt, 1.9×104/μl ; WBC, 12,700/μl with 18.5% abnormal cells. Computed tomography revealed an enhanced, irregular mass in her right breast as well as right axillary lymph node swelling, suggestive of breast cancer. BM biopsy confirmed the presence of abnormal, keratin-positive cells, suggesting metastasis to the bone. CA15-3 was 300U/㎖ (normal range <25). The patient died on April 11, 2011, post-admission day 20. We found a rare case of terminal breast cancer that presented with peripheral blood abnormality. Breast cancer in patients who do not notice breast abnormality can present with peripheral blood abnormality.
キーワード 乳癌(breast cancer) 初発症状(initial symptom) 貧血(anemia) 骨髄転移(bone marrow metastasis)
出版物タイトル 岡山医学会雑誌
発行日 2014-04-01
巻 126巻
号 1号
開始ページ 31
終了ページ 34
ISSN 0030-1558
関連URL http://www.okayama-u.ac.jp/user/oma/
言語 日本語
著作権者 Copyright (c) 2014 岡山医学会
論文のバージョン publisher
DOI 10.4044/joma.126.31
JaLCDOI 10.18926/fest/52227
タイトル(別表記) Numerical Evaluation of the Approximation by an Influence Function
フルテキストURL fest_019_001_007.pdf
著者 包 紅梅| 笛田 薫|
抄録 For evaluating statistical models one of the most effective criteria is cross-validation. But it requires a large amount of computation. Various alternative schemes are considered to reduce its computation. Modified generalized information criterion is one of those alternative schemes. In this criterion an influence function is used to estimate the parameters of the models. By the numerical simulation we studied the effect of an influence function.  Surveying data of the lake depth are used as the sample data. We estimate the shape of lake bottom as spline surface. The estimated parameters and the estimated depths obtained by two criteria are compared and the effect of an information function is analysed.
キーワード influence function information criteria CV mGIC B-spline
出版物タイトル 岡山大学環境理工学部研究報告
発行日 2014-03
巻 19巻
号 1号
開始ページ 1
終了ページ 7
ISSN 2187-6940
言語 英語
論文のバージョン publisher
NAID 120005394642
JaLCDOI 10.18926/AMO/52144
フルテキストURL 68_1_47.pdf
著者 Ishikawa, Tsutomu| Araki, Motoo| Hirata, Takeshi| Watanabe, Masami| Ebara, Shin| Watanabe, Toyohiko| Nasu, Yasutomo| Kumon, Hiromi|
抄録 We report 3 patients with the rare complication of an indwelling urethral catheter misdirected into the ureter. This is the largest series to date. Patients were referred to us for a variety of reasons following exchange of their chronic indwelling urinary catheters. CT in all cases demonstrated the urinary catheters residing in the left ureter. The ages of the patients were 37, 67 and 81 years old. All patients suffered from neurogenic bladder. Two patients were female, one was male, and 2 of the 3 had a sensory disorder inhibiting their pain response. The catheters were replaced with open-end Foley catheters. Extensive follow-up CT scans were obtained in one case, demonstrating improvement of hydronephrosis and no evidence of ureteral stenosis. Cystoscopy in this patient demonstrated normally positioned and functioning ureteral orifices. Although the placement of an indwelling urethral catheter is a comparatively safe procedure, one must keep in mind that this complication can occur, particularly in female patients with neurogenic bladder. CT without contrast is a noninvasive, definitive diagnostic tool.
キーワード complication indwelling urethral catheter imaging computed tomography ureter
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2014-02
巻 68巻
号 1号
出版者 Okayama University Medical School
開始ページ 47
終了ページ 51
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553489
Web of Science KeyUT 000331592800008
著者 Yamagishi, Hiroyuki| Watanabe, Kohtaro| Kametaka, Yoshinori|
発行日 2014-01
出版物タイトル Mathematical Journal of Okayama University
巻 56巻
号 1号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/mjou/52074
著者 Shiozaki, Yasuyuki| Kitajima, Takashi| Mazaki, Tetsuro| Yoshida, Aki| Tanaka, Masato| Umezawa, Akihiro| Nakamura, Mariko| Yoshida, Yasuhiro| Ito, Yoshihiro| Ozaki, Toshifumi| Matsukawa, Akihiro|
発行日 2013-04
出版物タイトル International Journal of Nanomedicine
巻 8巻
号 1号
資料タイプ 学術雑誌論文
著者 Matsubara, Minoru| Shiraha, Hidenori| Kataoka, Jyunro| Iwamuro, Masaya| Horiguchi, Shigeru| Nishina, Shin-ichi| Takaoka, Nobuyuki| Uemura, Masayuki| Takaki, Akinobu| Nakamura, Shinichiro| Kobayashi, Yoshiyuki| Nouso, Kazuhiro| Yamamoto, Kazuhide|
発行日 2012-10
出版物タイトル Journal of Gastroenterology and Hepatology
巻 27巻
号 10号
資料タイプ 学術雑誌論文
JaLCDOI 10.18926/AMO/52014
フルテキストURL 67_6_397.pdf
著者 Matsui, Yusuke| Mimura, Hidefumi| Fukazawa, Takuya| Morita, Ichiro| Suehiro, Mitsuhiko| Kawamoto, Hirofumi| Naomoto, Yoshio|
抄録 We describe an interesting clinical course of a patient who developed severe ischemic liver injury due to acute embolism of the superior mesenteric artery (SMA) and celiac artery. A 70-year-old man was hospitalized for abdominal pain and diarrhea. Abdominal computed tomography demonstrated a variant common hepatic artery arising from the SMA and multiple thromboembolic occlusions of visceral arteries, including the SMA and celiac artery. Laboratory data showed markedly elevated hepatic enzymes, which increased after admission despite the initiation of systemic anticoagulant and thrombolytic therapy. The patient was successfully treated by endovascular recanalization of the SMA occlusion via transcatheter embolus aspiration, thrombolysis, balloon angioplasty, and stent placement. Severe ischemic liver injury may occur in the setting of synchronous embolism of the SMA and celiac artery, and these phenomena may have a critical impact on the choice of treatment strategies and prognosis. Endovascular treatment appears to an effective treatment option.
キーワード superior mesenteric artery celiac artery embolism liver ischemia endovascular treatment
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2013-12
巻 67巻
号 6号
出版者 Okayama University Medical School
開始ページ 397
終了ページ 402
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24356725
Web of Science KeyUT 000328915700009