検索結果 24577 件
| タイトル（別表記） | Molecular targeted therapy in myeloma and lymphoma |
|---|---|
| フルテキストURL | 126_143.pdf |
| 著者 | 佐伯 恭昌| 前田 嘉信| 谷本 光音| |
| キーワード | 骨髄腫 リンパ腫 分子標的治療薬 |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 143 |
| 終了ページ | 150 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.143 |
| NAID | 130004685266 |
| タイトル（別表記） | A case of asymptomatic right-sided adult Bochdalek hernia presented incidentally with rectal tumor |
|---|---|
| フルテキストURL | 126_137.pdf |
| 著者 | 加藤 大| 大石 正博| 小寺 正人| 山村 方夫| 池田 秀明| 水野 憲治| 山下 裕| 鈴木 一則| |
| 抄録 | We encountered a patient with an adult Bochdalek hernia discovered asymptomatically. A 77-year-old Japanese woman visited a local clinic with chief complaints of melena and difficulty in defecation. Based on the results of the detailed examination in our hospital, she was diagnosed with a rectal gastrointestinal stromal tumor (GIST) with a concurrent asymptomatic adult right-sided Bochdalek hernia. Because the tumor was large, laparoscopic abdominoperineal rectal amputation was performed after systemic imatinib therapy. During the surgery, we found a right diaphragmatic defect more than 13cm in long dia., through which the right hepatic lobe, colon, and greater omentum had prolapsed into the right thoracic cavity. No visceral adhesions were noted. No hernia sac was observed. Adult Bochdalek hernia is a relatively rare condition, and only three (incidentally discovered) cases of asymptomatic Bochdalek hernia, including the present case, have been reported in Japan. Here we provide a case report for the patient, who was followed-up without hernia surgery, plus a review of the literature. |
| キーワード | 成人Bochdalek孔ヘルニア（adult Bochdalek hernia） 腹腔鏡下手術（laparoscopic surgery） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 137 |
| 終了ページ | 141 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.137 |
| NAID | 130004685265 |
| タイトル（別表記） | Treatment for a non-compliant patient with cancer and epilepsy |
|---|---|
| フルテキストURL | 126_133.pdf |
| 著者 | 南 大輔| 市原 英基| 岡部 伸幸| 横道 直佑| 高下 典子| 鍛治園 誠| 秋元 悠| 堀 圭介| 松原 稔| 那須 淳一郎| 谷本 光音| 木浦 勝行| 松岡 順治| |
| 抄録 | A 58-year-old man with cervical esophageal cancer and a history of epilepsy was treated with chemoradiotherapy from May of 2013. When tube feeding was initiated due to aspiration pneumonitis, the patient showed a degree of irritability that affected routine staff work and treatment compliance. We attempted to perform supportive care for maladjustment by the notice, the fast, and the tube feeding, but there was no improvement. After we added carbamazepine, primidone, and propericiazine (which had been canceled at the initiation of the tube feeding) to the patient's intravenous phenytoin, the symptoms and treatment compliance improved significantly. We concluded that the causes of the patient's irritability were maladjustment and his epilepsy. |
| キーワード | てんかん（epilepsy） 易怒性（irritability） 適応障害（maladjustment） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 133 |
| 終了ページ | 135 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.133 |
| NAID | 130004685264 |
| タイトル（別表記） | Fermented persimmon extract (kaki-shibu) is useful as a standard for component analyses of persimmon phytobezoars |
|---|---|
| フルテキストURL | 126_127.pdf |
| 著者 | 岩室 雅也| 岡本 裕子| 村田 年弘| 河合 良成| 白羽 英則| 岡田 裕之| 山本 和秀| |
| 抄録 | The definite diagnosis of persimmon phytobezoar (i.e., diospyrobezoar) is often accomplished by a component analysis using infrared spectroscopy. However, no studies have been conducted to investigate which substance is the best as a standard for the component analysis. Here we analyzed tannic acid, Japanese persimmon (kaki), fermented persimmon extract (kaki-shibu), conventional dried persimmon, and dried persimmon smoked in sulfur (ampo-kaki) by infrared spectroscopy to determine which would be optimal as a component analysis standard. The spectrum between 1,600 to 600cm－1 of a persimmon phytobezoar was quite similar to the spectrum of kaki-shibu rather than that of tannic acid. Consequently, we conclude that kaki-shibu should be used as a standard for infrared spectroscopy analyses of persimmon phytobezoars. |
| キーワード | 柿胃石（gastric phytobezoar） タンニン酸（tannic acid） 消化管異物（gastrointestinal foreign body） 成分分析（component analysis） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 127 |
| 終了ページ | 131 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.127 |
| NAID | 130004685263 |
| タイトル（別表記） | The origin of infra-slow oscillations of oxygenated hemoglobin observed in functional near-infrared spectroscopy |
|---|---|
| フルテキストURL | 126_117.pdf |
| 著者 | 所司 睦文| 上野 浩司| 久保 正子| 小田 真珠子| 平田 直也| 武本 梨佳| 衣笠 和孜| 岡本 基| |
| 抄録 | There is increasing interest in the intrinsic activity of the resting brain, especially the activity slower than 0.1Hz (i.e., low-frequency oscillations, or LFOs). To investigate the origin of LFOs observed in functional near-infrared spectroscopy (fNIRS), we recorded multichannel fNIRS and electroencephalography (EEG) from the frontal cortex of 11 healthy young volunteers in the resting state. Electrocardiography (ECG), electro-oculography and respiration were also measured. Synchronous oscillations of oxy-hemoglobin (oxy-Hb) around 1.0Hz were detected in all fNIRS channels, and their frequency was consistent with a peak frequency of ECG, suggesting the changes of cerebral blood flow due to heart beats. In addition, oxy-Hb oscillations around 0.1Hz (i.e., LFOs) appeared in the fNIRS. The channels where LFOs appeared differed among the subjects, and the LFOs appeared or disappeared even in the same fNIRS channels. The appearance of LFOs in fNIRS channels was significantly higher when the LFOs appeared on the EEG in the adjacent EEG electrodes compared to when LFOs did not appear on EEG. The amplitude and coherence (synchronicity) of the LFOs were increased by changing the subjects' position from dorsal to the sitting position in both fNIRS and EEG, and the coherence in particular was increased in the homologous fNIRS channels on the bilateral hemispheres. These results suggest that LFOs of oxy-Hb couple with resting-state EEG activity. |
| キーワード | fNIRS EEG LFOs コヒーレンス解析（Coherence analysis） 連続ウェーブレット解析（continuous wavelet transforms） |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 117 |
| 終了ページ | 126 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.117 |
| NAID | 130004685262 |
| タイトル（別表記） | Comprehensive treatment for gender identity disorder |
|---|---|
| フルテキストURL | 126_109.pdf |
| 著者 | 難波 祐三郎| |
| キーワード | 性同一性障害 包括的治療 性別適合手術 |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 109 |
| 終了ページ | 115 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.109 |
| NAID | 130004685261 |
| タイトル（別表記） | Induction therapy followed by surgery for non small-cell lung cancer |
|---|---|
| フルテキストURL | 126_103.pdf |
| 著者 | 豊岡 伸一| |
| キーワード | 非小細胞肺癌 導入療法 放射線化学療法 外科切除 |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 103 |
| 終了ページ | 107 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.103 |
| NAID | 130004685260 |
| タイトル（別表記） | The 2013 Incentive Award of the Okayama Medical Association in Neuroscience (2013 Niimi Prize) |
|---|---|
| フルテキストURL | 126_99.pdf |
| 著者 | 大島 悦子| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 99 |
| 終了ページ | 102 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.99 |
| NAID | 130004685277 |
| タイトル（別表記） | The 2013 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2013 Sunada Prize) |
|---|---|
| フルテキストURL | 126_95.pdf |
| 著者 | 中司 敦子| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 95 |
| 終了ページ | 98 |
| ISSN | 0030-1558 |
| 関連URL | http://www.okayama-u.ac.jp/user/oma/ |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.95 |
| NAID | 130004685276 |
| タイトル（別表記） | The 2013 Incentive Award of the Okayama Medical Association in Cancer Research (2013 Hayashibara Prize and Yamada Prize) |
|---|---|
| フルテキストURL | 126_93.pdf |
| 著者 | 大原 利章| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 93 |
| 終了ページ | 94 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.93 |
| NAID | 120005468246 |
| タイトル（別表記） | The 2013 Incentive Award of the Okayama Medical Association in Cancer Research (2013 Hayashibara Prize and Yamada Prize) |
|---|---|
| フルテキストURL | 126_89.pdf |
| 著者 | 長谷井 嬢| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 89 |
| 終了ページ | 92 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.89 |
| NAID | 130004685274 |
| タイトル（別表記） | The 2013 Incentive Award of the Okayama Medical Association in Cancer Research (2013 Hayashibara Prize and Yamada Prize) |
|---|---|
| フルテキストURL | 126_87.pdf |
| 著者 | 宮原 孝治| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 87 |
| 終了ページ | 88 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.87 |
| NAID | 120005468244 |
| タイトル（別表記） | The 2013 Incentive Award of the Okayama Medical Association in General Medical Science (2013 Yuuki Prize) |
|---|---|
| フルテキストURL | 126_83.pdf |
| 著者 | 村田 等| |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2014-08-01 |
| 巻 | 126巻 |
| 号 | 2号 |
| 開始ページ | 83 |
| 終了ページ | 86 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2014 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.126.83 |
| NAID | 130004685272 |
| 著者 | MANO, Akiko| MALVE, Olli| KOPONEN, Sampsa| KALLIO, Kari| TASKINEN, Antti| ROPPONEN, Janne| JUNTUNEN, Janne| LIUKKO, Ninni| |
|---|---|
| 発行日 | 2014-06 |
| 出版物タイトル | SYKE-OU Project Report |
| 資料タイプ | 研究報告書 |
| 著者 | WU, Ting Feng| OKUBO, Kenji| HUTTULA, Timo| ROPPONEN, Janne| |
|---|---|
| 発行日 | 2014-06 |
| 出版物タイトル | SYKE-OU Project Report |
| 資料タイプ | 研究報告書 |
| JaLCDOI | 10.18926/AMO/52660 |
|---|---|
| フルテキストURL | 68_3_183.pdf |
| 著者 | Hasegawa, Kenjiro| Namba, Yuzaburo| Kimata, Yoshihiro| |
| 抄録 | Since 2001, we have been performing phalloplasty with a radial forearm free flap as the flap of first choice in female-to-male transsexuals (FTMTS). In the present case, a 22-year-old FTMTS with a negative Allen test, we achieved good results by performing phalloplasty with an innervated island pedicled anterolateral thigh flap using the “tube within a tube” technique, in which the penis and urethra are constructed with a single flap. As compared to a forearm flap, use of an innervated islandpedicled flap may have the following advantages in phalloplasty: 1) no need for a microsurgical technique; 2) no scars at noticeable sites; 3) small functional loss in the flap donor area; 4) no sacrifice of major blood vessels. Thus, this technique seems to be a useful clinical alternative for phallic reconstruction. |
| キーワード | gender identity disorder sex reassignment surgery (SRS) phalloplasty |
| Amo Type | Corrected and Republished Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 183 |
| 終了ページ | 190 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24945633 |
| Web of Science KeyUT | 000337655600009 |
| 関連URL | http://doi.org/10.18926/AMO/51869 |
| JaLCDOI | 10.18926/AMO/52659 |
|---|---|
| フルテキストURL | 68_3_177.pdf |
| 著者 | Mizuno, Shoma| Ota, Seisuke| Tanaka, Takehiro| Shiomi, Kohei| Matsumura, Tadashi| Kishimoto, Nobuyasu| |
| 抄録 | Primary tracheal malignant lymphoma is a rare disease;only 30 cases have been reported to date. A 73-year-old Japanese man with a history of asbestos exposure was undergoing biannual chest computed tomography (CT) twice a year as a routine procedure for those previously exposed to asbestos. He had been smoking since the age of 32. In September 2010, chest CT during this regular checkup revealed a polypoid lesion in his trachea and pleural plaques, which were suspected to be caused by asbestos. Bronchoscopy performed in October revealed a polypoid lesion with granules and nodules in the trachea. A diagnosis of non-Hodgkin lymphoma (NHL) and extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) was confirmed by histological analysis of the biopsy specimens. To our knowledge, this is the first case of primary tracheal lymphoma associated with a history of asbestos exposure. Several reports have documented no correlation between asbestos and malignant lymphoma. In addition, the correlation between smoking and NHL is weak. Although we cannot exclude the possibility of a simple coincidence of asbestos, smoking, and tracheal lymphoma, this case suggests that asbestos and smoking might have multiplicative effects in the development or progression of tracheal lymphoma. |
| キーワード | bronchus-associated lymphoid tissue tracheal lymphoma regular checkup asbestos smoking |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 177 |
| 終了ページ | 181 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942797 |
| Web of Science KeyUT | 000337655600008 |
| JaLCDOI | 10.18926/AMO/52658 |
|---|---|
| フルテキストURL | 68_3_171.pdf |
| 著者 | Hagiya, Hideharu| Matsumoto, Mitsuaki| Yamasawa, Takahiko| Haruki, Yuto| Otsuka, Fumio| |
| 抄録 | A 79-year-old man who had undergone a right femoropopliteal (FP) bypass operation 6 weeks previously was diagnosed with vascular graft infection caused by Staphylococcus lugdunensis. Another FP bypass operation was performed, with long-term administration of antibiotics, and the patient eventually recovered well without any recurrences for over 2 years. Although S. lugdunens is classified as coagulase-negative Staphylococcus, its pathogenicity has been reported to be equal to that of S. aureus. Based on the literature review, the organism characteristically colonizes the inguinal area of human skin;thus, operations such as FP bypass grafting may place patients at a relatively high risk for infection by S. lugdunensis, a potentially high-pathogenicity organism. |
| キーワード | coagulase-negative Staphylococcus (CNS) femoropopliteal (FP) bypass Staphylococcus lugdunensis vacuum-assisted closure (VAC) therapy vascular graft infection (VGI) |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 171 |
| 終了ページ | 175 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942796 |
| Web of Science KeyUT | 000337655600007 |
| JaLCDOI | 10.18926/AMO/52657 |
|---|---|
| フルテキストURL | 68_3_163.pdf |
| 著者 | Tate, Genshu| Kishimoto, Koji| Mitsuya, Toshiyuki| |
| 抄録 | The aim of the present study is to address whether the molecular pathogenesis is identical among multiple basal cell carcinomas (BCCs) present in the same nevoid basal cell carcinoma syndrome (NBCCS) patient. Patient 1 is a 61-year-old (yo) Japanese female whose clinical characteristics and findings of a genetic analysis of PTCH1 have been previously described. Patient 2 is patient 1ʼs 64-yo sister who also suffered from NBCCS with a single base deletion at nucleotide 2613 in exon 16 (c.2613delC) in one PTCH1 allele. Thirteen and 3 independent specimens of BCC were applied for a molecular analysis of loss of heterozygosity (LOH) in PTCH1 in patients 1 and 2, respectively. Of particular note is that all BCC specimens examined showed a loss of the wild-type allele of exon 16 in PTCH1, thus indicating that LOH results in the biallelic disruption of PTCH1 in multiple BCCs that develop in an age- and location-independent manner in the same patient. These results indicate that the germline single base deletion of PTCH1 (c.2613 delC) is a first hit and the LOH of the wild-type allele is a second hit, implying that all 16 BCCs detected in these NBCCS sisters fit the standard two-hit model. |
| キーワード | biallelic disruption hedgehog nevoid basal cell carcinoma syndrome Patched 1 two-hit model |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 163 |
| 終了ページ | 170 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942795 |
| Web of Science KeyUT | 000337655600006 |
| JaLCDOI | 10.18926/AMO/52656 |
|---|---|
| フルテキストURL | 68_3_157.pdf |
| 著者 | Oozawa, Susumu| Sano, Shunji| Nishibori, Masahiro| |
| 抄録 | Atherosclerosis is often associated with chronic vascular inflammation. High-mobility group box 1 protein (HMGB1) plays various roles, not only as a transcriptional regulatory factor in the nucleus, but also as an inflammatory mediator. A previous study suggested that fibrinogen is an important factor associated with atherosclerosis progression. The present study was performed to examine the levels of plasma HMGB1 protein in atherosclerosis patients. We studied 24 patients with peripheral artery disease (PAD) with atherosclerosis, and 10 healthy controls. We found that the concentrations of HMGB1 were increased in the plasma of the patients with atherosclerosis, and there were significant correlations between the plasma HMGB1 and fibrinogen levels. Plasma HMGB1 may play a key role in the pathogenesis of clinical and experimental atherosclerosis. |
| キーワード | HMGB1 fibrinogen atherosclerosis peripheral artery disease |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2014-06 |
| 巻 | 68巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 157 |
| 終了ページ | 162 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2014 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 24942794 |
| Web of Science KeyUT | 000337655600005 |
| 関連URL | http://doi.org/10.18926/AMO/52792 |