検索結果 3119 件
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Yamamoto, Koichiro| Hagiya, Hideharu| Maki, Jota| Okahara, Shuji| Hasegawa, Kou| Otsuka, Fumio| |
| キーワード | covid-19 cytokine storm pneumonia pregnancy steroids |
| 発行日 | 2021-08-23 |
| 出版物タイトル | Cureus |
| 巻 | 13巻 |
| 号 | 8号 |
| 出版者 | Cureus Inc |
| 開始ページ | e17398 |
| ISSN | 2168-8184 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 Yamamoto et al. |
| 論文のバージョン | publisher |
| DOI | 10.7759/cureus.17398 |
| Web of Science KeyUT | 000688329400025 |
| 関連URL | isVersionOf https://doi.org/10.7759/cureus.17398 |
| フルテキストURL | fulltext20210902-1.pdf |
|---|---|
| 著者 | Sato, Kazuhiro| Mascher, Martin| Himmelbach, Axel| Haberer, Georg| Spannagl, Manuel| Stein, Nils| |
| キーワード | genome assembly Hordeum vulgare ssp. spontaneum OUH602 pseudomolecules wild barley |
| 備考 | This is an Open Access article distributed under the terms of the Creative Commons Attribution License.| |
| 発行日 | 2021-7-13 |
| 出版物タイトル | G3 Genes|Genomes|Genetics |
| 出版者 | Oxford University Press (OUP) |
| 開始ページ | jkab244 |
| ISSN | 2160-1836 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | (C) The Author(s) 2021. |
| 論文のバージョン | publisher |
| DOI | 10.1093/g3journal/jkab244 |
| 関連URL | isVersionOf https://doi.org/10.1093/g3journal/jkab244 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Takemoto, Rika| Uchida, Haruhito A.| Toda, Hironobu| Okada, Ken| Otsuka, Fumio| Ito, Hiroshi| Wada, Jun| |
| キーワード | augmentation index augmentation pressure peripheral arterial disease total vascular resistance |
| 発行日 | 2021-08-13 |
| 出版物タイトル | Medicine |
| 巻 | 100巻 |
| 号 | 32号 |
| 出版者 | Wolters Kluwer Health, Inc. |
| 開始ページ | e26931 |
| ISSN | 0025-7974 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 the Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 34397939 |
| DOI | 10.1097/MD.0000000000026931 |
| Web of Science KeyUT | 000683492600068 |
| 関連URL | isVersionOf https://doi.org/10.1097/MD.0000000000026931 |
| フルテキストURL | fulltext20210818-1.pdf |
|---|---|
| 著者 | Hagiya, Hideharu| Fujita, Koji| Kamiyama, Shinya| Ocho, Kazuki| Yamada, Haruto| Otsuka, Fumio| |
| キーワード | antimicrobial resistance certified nurses in infection control infection prevention and control infectious disease doctors japan nosocomial infections surveillance |
| 発行日 | 2021-07-26 |
| 出版物タイトル | Cureus |
| 巻 | 13巻 |
| 号 | 7号 |
| 出版者 | Cureus Inc. |
| 開始ページ | e16643 |
| ISSN | 2168-8184 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © Copyright 2021 Hagiya et al. |
| 論文のバージョン | publisher |
| DOI | 10.7759/cureus.16643 |
| Web of Science KeyUT | 000680008700016 |
| 関連URL | isVersionOf https://doi.org/10.7759/cureus.16643 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Habu, Hiroshi| Takao, Soshi| Fujimoto, Ryohei| Naito, Hiromichi| Nakao, Atsunori| Yorifuji, Takashi| |
| キーワード | COVID-19 epidemiology emergency medical dispatch suicide |
| 発行日 | 2021-07-17 |
| 出版物タイトル | Journal of Epidemiology |
| 巻 | 31巻 |
| 号 | 9号 |
| 出版者 | Japan Epidemiological Assoc. |
| 開始ページ | 511 |
| 終了ページ | 517 |
| ISSN | 0917-5040 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 Hiroshi Habu et al. |
| 論文のバージョン | publisher |
| PubMed ID | 34176855 |
| DOI | 10.2188/jea.JE20210066 |
| Web of Science KeyUT | 000680719500003 |
| 関連URL | isVersionOf https://doi.org/10.2188/jea.JE20210066 |
| 著者 | Akao, Yohei| Yamauchi, Toshihiro| |
|---|---|
| 発行日 | 2016-12 |
| 出版物タイトル | 2016 International Conference on Information Science and Security (ICISS) |
| 資料タイプ | 会議発表論文 |
| フルテキストURL | fulltext20210726-1.pdf |
|---|---|
| 著者 | Liu, Shihui| Matsuo, Toshihiko| Miyaji, Mary| Hosoya, Osamu| |
| キーワード | NK-4 retina apoptosis RNA-seq photoreceptor retinitis pigmentosa antioxidant metabolism |
| 発行日 | 2021-7-19 |
| 出版物タイトル | Pharmaceuticals |
| 巻 | 14巻 |
| 号 | 7号 |
| 出版者 | MDPI AG |
| 開始ページ | 694 |
| ISSN | 1424-8247 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 by the authors. Licensee MDPI, Basel, Switzerland. |
| 論文のバージョン | publisher |
| DOI | 10.3390/ph14070694 |
| 関連URL | isVersionOf https://doi.org/10.3390/ph14070694 |
| フルテキストURL | fulltext20210721-2.pdf figure20210721-2.pdf |
|---|---|
| 著者 | Watari, Shogo| Araki, Motoo| Wada, Koichiro| Yoshinaga, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Kobayashi, Yasuyuki| Takeuchi, Hidemi| Tanabe, Katsuyuki| Kitagawa, Masashi| Morinaga, Hiroshi| Kitamura, Shinji| Sugiyama, Hitoshi| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| 備考 | © 2021 Published by Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.transproceed.2021.03.043] . | |
| 発行日 | 2021-4-28 |
| 出版物タイトル | Transplantation Proceedings |
| 巻 | 53巻 |
| 号 | 5号 |
| 出版者 | Elsevier BV |
| 開始ページ | 1494 |
| 終了ページ | 1500 |
| ISSN | 0041-1345 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 33931247 |
| DOI | 10.1016/j.transproceed.2021.03.043 |
| Web of Science KeyUT | 000668604400017 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.transproceed.2021.03.043 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tahjib-Ul-Arif, Md.| Zahan, Mst, Ishrat| Karim, Md. Masudul| Imran, Shahin| Hunter, Charles T.| Islam, Md. Saiful| Mia, Md. Ashik| Hannan, Md. Abdul| Rhaman, Mohammad Saidur| Hossain, Md. Afzal| Brestic, Marian| Skalicky, Milan| Murata, Yoshiyuki| |
| キーワード | citrate heavy metal stress drought stress antioxidant reactive oxygen species salinity aluminum toxicity |
| 発行日 | 2021-07-05 |
| 出版物タイトル | International Journal of Molecular Sciences |
| 巻 | 22巻 |
| 号 | 13号 |
| 出版者 | MDPI |
| 開始ページ | 7235 |
| ISSN | 1422-0067 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 by the authors. |
| 論文のバージョン | publisher |
| DOI | 10.3390/ijms22137235 |
| Web of Science KeyUT | 000671283500001 |
| 関連URL | isVersionOf https://doi.org/10.3390/ijms22137235 |
| JaLCDOI | 10.18926/OER/62263 |
|---|---|
| タイトル（別表記） | Die Debatte über Nationalitätenpolitik im österreichischen Kaiserreich |
| フルテキストURL | oer253_3_019_033.pdf |
| 著者 | 太田 仁樹| |
| 出版物タイトル | 岡山大学経済学会雑誌 |
| 発行日 | 2021-07-12 |
| 巻 | 53巻 |
| 号 | 1号 |
| 開始ページ | 19 |
| 終了ページ | 33 |
| ISSN | 2433-4146 |
| 言語 | 日本語 |
| 著作権者 | Copyright © 2021 岡山大学経済学会 |
| 論文のバージョン | publisher |
| フルテキストURL | fulltext20210706-2.pdf |
|---|---|
| 著者 | Kidani, Naoya| Sugiu, Kenji| Terasaka, Kaoru| Nakashima, Hiroyuki| Tokunaga, Koji| Kobayashi, Kazuki| Kambara, Hirokazu| Hishikawa, Tomohito| Hiramatsu, Masafumi| Date, Isao| |
| 備考 | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00701-021-04885-1| |
| 発行日 | 2021-6-19 |
| 出版物タイトル | Acta Neurochirurgica |
| 巻 | 164巻 |
| 号 | 2号 |
| 出版者 | Springer Science and Business Media LLC |
| 開始ページ | 517 |
| 終了ページ | 523 |
| ISSN | 0001-6268 |
| NCID | AA0050885X |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | author |
| PubMed ID | 34146152 |
| DOI | 10.1007/s00701-021-04885-1 |
| Web of Science KeyUT | 000663495400001 |
| 関連URL | isVersionOf https://doi.org/10.1007/s00701-021-04885-1 |
| JaLCDOI | 10.18926/AMO/62235 |
|---|---|
| フルテキストURL | 75_3_385.pdf |
| 著者 | Okita, Atsushi| Fujimura, Masaki| Sato, Isao| Chino, Yoshihide| Yuba, Takafumi| Mizutani, Makoto| Tabata, Tomotake| Iida, Minoru| Kumano, Kimitsuka| |
| Amo Type | Case Report |
| 備考 | We report an extremely rare case of a centenarian with acute appendicitis that was successfully managed via emergent surgery. A 109-year-old woman was referred to Daiichi Towakai Hospital with a high fever and nausea. She presented with peritoneal irritation, and computed tomography showed a swollen appendix with intraluminal fecolith. She was diagnosed with acute appendicitis and underwent appendectomy, which was performed via an open approach under spinal anesthesia. The patient’s postoperative course was uneventful. As for treatment planning for centenarians, comprehensive and exhaustive discussions with the patient and family members should be encouraged under the principals of narrative medicine.| |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 385 |
| 終了ページ | 389 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176944 |
| Web of Science KeyUT | 000667147700015 |
| NAID | 120007089820 |
| JaLCDOI | 10.18926/AMO/62234 |
|---|---|
| フルテキストURL | 75_3_381.pdf |
| 著者 | Yamamoto, Ken-ichi| Oshiki, Toshiyuki| Kagawa, Hiroko| Namba, Masayoshi| Sakaguchi, Masakiyo| |
| 抄録 | The worldwide microplastic pollution in our environment is a matter of great concern. Harmful effects of plastics have been reported in various types of organisms including murine animals. We examined the presence of microplastics in four types of shellfish purchased from fish markets in Okayama, Japan and served to the public: short-neck clam (Ruditapes philippinarum, asari in Japanese), hard-shell clam (Meretrix lusoria, hamaguri), brackishwater clam (Cyrenidae, shijimi), and oyster (Crassostrea gigas, kaki). Our analyses demonstrated that approx. 3 pieces of microplastics were present per single shellfish, based on the division of the total number of pieces of microplastic obtained from all 4 types of shellfish by the total number of shellfish examined. Since health problems in humans due to microplastics have not yet been confirmed, further examinations of the effects of ingested microplastics are needed. |
| キーワード | microplastics, shellfish Japan health effect pollution |
| Amo Type | Short Communication |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 381 |
| 終了ページ | 384 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176943 |
| Web of Science KeyUT | 000667147700014 |
| NAID | 120007089831 |
| JaLCDOI | 10.18926/AMO/62233 |
|---|---|
| フルテキストURL | 75_3_373.pdf |
| 著者 | Yaylali, Guzin F.| Dedeoglu, Ozen | Topsakal, Senay| Herek, Duygu| Senol, Hande| |
| 抄録 | Osteocalcin (OC) is inversely related to body fat distribution and fasting glucose levels. We sought to observe the effect of OC on fat distribution and subclinical atherosclerosis as measured by carotid intima-media thickness (CIMT) in premenopausal obese women. In this prospective observational study, totally, 73 premenopausal obese women (aged 17-55 years) and 53 healthy women (aged 20-50 years) with normal weight were included as controls. Anthropometric measurements, total fat and fat ratio, insulin, fasting blood glucose, and OC levels were estimated. Ultrasonography was used to assess fat distribution, and fat thickness was measured in 4 regions. Subcutaneous fat (SCF), visceral fat (VF), and preperitoneal fat (PPF) thicknesses were considerably higher in obese subjects (p<0.01) than healthy controls, while OC levels were significantly lower. No correlation was observed between OC levels and SCF, VF, or PPF. In a multiple regression analysis, OC was significantly positively associated with SCF (p=0.04, Beta=0.284). No associations were observed between OC levels and VF, PPF, or CIMT. A significant association was observed between parathyroid hormone (PTH) and VF (p=0.021, Beta=0.284), and vitamin D levels were inversely associated with VF (p=0.002, r=−0.366). OC levels were lower in premenopausal obese women than normal-weight healthy controls, but OC exhibited no correlation with VF or PPF, and only a weak positive association with SCF. Additionally, VF was positively correlated with PTH and inversely correlated with vitamin D. These results suggest that OC may be an early indicator of lipid accumulation in te subcutaneous area and development of atherosclerosis. |
| キーワード | body fat composition carotid intima-media thickness obesity osteocalcin premenopausal women |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 373 |
| 終了ページ | 379 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176942 |
| Web of Science KeyUT | 000667147700013 |
| NAID | 120007089830 |
| JaLCDOI | 10.18926/AMO/62231 |
|---|---|
| フルテキストURL | 75_3_357.pdf |
| 著者 | Takabatake, Daisuke| Kajiwara, Yukiko| Ohtani, Shoichiro| Suzuki, Yoko| Yamamoto, Mari| Kubo, Shinichiro| Ikeda, Masahiko| Takahashi, Mina| Hara, Fumikata| Aogi, Kenjiro| Ohsumi, Shozo| Ogasawara, Yutaka| Nishiyama, Yoshitaka| Hikino, Hajime| Matsuoka, Kinya| Shien, Tadahiko| Taira, Naruto| Doihara, Hiroyoshi| |
| 抄録 | Perioperative dose-dense chemotherapy (DDCT) with pegfilgrastim (Peg) prophylaxis is a standard treatment for high-risk breast cancer. We explored the optimal timing of administration of 3.6 mg Peg, the dose approved in Japan. In the phase II feasibility study of DDCT (adriamycin+cyclophosphamide or epirubicin+cyclophosphamide followed by paclitaxel) for breast cancer, we investigated the feasibility, safety, neutrophil transition, and optimal timing of Peg treatment by administering Peg at days 2, 3, and 4 post-chemotherapy (P2, P3, and P4 groups, respectively). Among the 52 women enrolled, 13 were aged > 60 years. The anthracycline sequence was administered to P2 (n=33), P3 (n=5), and P4 (n=14) patients, and the taxane sequence to P2 (n=38) and P3 (n=6) patients. Both sequences showed no interaction between Peg administration timing and treatment discontinuation, treatment delay, or dose reduction. However, the relative dose intensity (RDI) was significantly different among the groups. The neutrophil count transition differed significantly among the groups receiving the anthracycline sequence. However, the neutrophil count remained in the appropriate range for both sequences in the P2 group. The timing of Peg administration did not substantially affect the feasibility or safety of DDCT. Postoperative day 2 might be the optimal timing for DDCT. |
| キーワード | dose-dense chemotherapy breast cancer pegfilgrastim |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 357 |
| 終了ページ | 362 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176940 |
| Web of Science KeyUT | 000667147700011 |
| NAID | 120007089828 |
| JaLCDOI | 10.18926/AMO/62228 |
|---|---|
| フルテキストURL | 75_3_335.pdf |
| 著者 | Chikuie, Nobuyuki| Hamamoto, Takao| Ueda, Tsutomu| Taruya, Takayuki| Kono, Takashi| Furuie, Hiromi| Ishino, Takashi| Takeno, Sachio| |
| 抄録 | Recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) has a poor prognosis. Although nivolumab is approved in Japan for treating R/MHNSCC, the response rate is low. Therefore, identifying pretreatment prognostic factors is necessary. This study assessed the utility of the neutrophil-to-lymphocyte ratio (NLR) and Glasgow Prognostic Score (GPS) as biomarkers of response to nivolumab. We retrospectively collected the data of 56 R/MHNSCC patients treated with nivolumab between May 2017 and December 2019. The Kaplan–Meier method and log-rank test were used to estimate overall survival (OS) and progression-free survival (PFS), and multivariate Cox hazard regression analysis was used to identify independent predictors of survival. Patients with a low pretreatment NLR had prolonged OS, and patients with a low pretreatment GPS had increased OS and PFS. A performance score (PS) of 0-1, development of immune-related adverse events, and GPS of 0-1 were significantly associated with OS in multivariate analysis. In summary, baseline pretreatment NLR and GPS are independently associated with OS in R/MHNSCC patients treated with nivolumab. Administration of nivolumab while maintaining the PS reflects a immune status of the host and leads to a good OS. |
| キーワード | neutrophil-to-lymphocyte ratio nivolumab Glasgow Prognostic Score recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 335 |
| 終了ページ | 343 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176937 |
| Web of Science KeyUT | 000667147700008 |
| NAID | 120007089825 |
| JaLCDOI | 10.18926/AMO/62227 |
|---|---|
| フルテキストURL | 75_3_323.pdf |
| 著者 | Furutani, Michiyo| Yu, Zhou| Nakatsuka, Mikiya| |
| 抄録 | Gender expression is important for transgender women to improve their social passing as women. Herein, a questionnaire about the status of gender expression and support needs was distributed to 54 transgender women aged 17-71 in Japan. Most of the respondents noted that they had found it relatively difficult to handle physical changes and weight gain due to hormone treatment. They also found it difficult to enact and sustain practices such as a feminine use of voice and to use women-only services, whereas practicing and continuing with routine skin and hair care and feminine mannerisms were relatively easy for them. In the questionnaire regarding the support for gender transitioning, many items showed only a small percentage of the transgender women had received the support that they were looking for, and most of their needs for support were not addressed. Some of the factors that increased the respondents’ needs and achievement of gender expression as women included estrogen treatment, sex reassignment surgery, and living as a woman; these aspects met their support needs as well. Gender support professionals need to coordinate and collaborate with specialists in areas such as nutritional guidance and voice training to enable transgender women to improve the extent to which they can socially ‘pass’ as women. |
| キーワード | transgender gender expression social passing as a woman real life experience gender transition |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 323 |
| 終了ページ | 334 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176936 |
| Web of Science KeyUT | 000667147700007 |
| NAID | 120007089824 |
| JaLCDOI | 10.18926/AMO/62225 |
|---|---|
| フルテキストURL | 75_3_307.pdf |
| 著者 | Ishizaka, Hinata| Kuroda, Masahiro| Tekiki, Nouha| Khasawneh, Abdullah| Barham, Majd| Hamada, Kentaro| Konishi, Kohei| Sugimoto, Kohei| Katsui, Kuniaki| Sugiyama, Soichi| Watanabe, Kenta| Yoshio, Kotaro | Katayama, Norihisa| Ogata, Takeshi| Ihara, Hiroki| Oita, Masataka| Kanazawa, Susumu| Asaumi, Junichi| |
| 抄録 | Reports on irradiation dose distribution in breast cancer radiotherapy with sufficient sample size are limited in Asian patients. Elucidating dose distribution in Asian patients is particularly important as their breast volume differs compared to patients in Europe and North America. Here, we examined dose distribution in the irradiation field relative to breast volume for three irradiation methods historically used in our facility. We investigated the influence of breast volume on each irradiation method for Asian women. A total of 573 women with early-stage breast cancer were treated with breast-conserving surgery and adjuvant radiotherapy. Three methods were compared: wedge (W), field-in-field (FIF), and wedge-field-in-field (W-FIF). In patients with small breast volume, FIF decreased low- and high-dose areas within the planning target volume, and increased optimal dose area more than W. In patients with medium and large breast volumes, FIF decreased high-dose area more than W. The absolute values of correlation coefficients of breast volume to low-, optimal-, and high-dose areas and mean dose were significantly lower in FIF than in W. The correlation coefficients of V107% were 0.00 and 0.28 for FIF and W, respectively. FIF is an excellent irradiation method that is less affected by breast volume than W in Asian breast cancer patients. |
| キーワード | breast cancer radiotherapy dose distribution irradiation method breast volume |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 307 |
| 終了ページ | 314 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176934 |
| Web of Science KeyUT | 000667147700006 |
| NAID | 120007089838 |
| フルテキストURL | fulltext20210623-2.pdf figure20210623-2.pdf |
|---|---|
| 著者 | Otsuka, Yuki| Hagiya, Hideharu| Nakano, Yasuhiro| Omura, Daisuke| Hasegawa, Kou| Yamada, Haruto| Iio, Koji| Honda, Tomoyuki| Otsuka, Fumio| |
| キーワード | Human coronavirus Coronavirus disease 2019 Severe acute respiratory syndrome coronavirus 2 |
| 備考 | © 2021 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.jiac.2021.05.001| |
| 発行日 | 2021-7 |
| 出版物タイトル | Journal of Infection and Chemotherapy |
| 巻 | 27巻 |
| 号 | 7号 |
| 出版者 | Elsevier BV |
| 開始ページ | 1126 |
| 終了ページ | 1128 |
| ISSN | 1341-321X |
| NCID | AA11057978 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2021 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. |
| 論文のバージョン | author |
| PubMed ID | 33994323 |
| DOI | 10.1016/j.jiac.2021.05.001 |
| Web of Science KeyUT | 000656910200036 |
| 関連URL | isVersionOf https://doi.org/10.1016/j.jiac.2021.05.001 |
| JaLCDOI | 10.18926/AMO/62221 |
|---|---|
| フルテキストURL | 75_3_299.pdf |
| 著者 | Araki, Jo| Oka, Kosuke| Yamamoto, Koichiro| Hanayama, Yoshihisa | Tokumasu, Kazuki| Hagiya, Hideharu| Ogawa, Hiroko| Itoshima, Koichi| Otsuka, Fumio| |
| 抄録 | Various laboratory markers of inflammation are utilized in general practice, but their clinical diagnostic significance is often ambiguous. In the present study, we determined the clinical significance of the examination of serum levels of procalcitonin (PCT) by comparing the PCT levels with the levels of other inflammatory markers, based on a retrospective review of 332 PCT-positive patients, including cases of bacterial infection (20.5%), non-specific inflammation (20.8%), neoplasm (9.9%), connective tissue diseases (8.4%), and non-bacterial infection (7.2%), were analyzed. The serum PCT level was highest in the bacterial infection group (1.94 ng/ml) followed by the non-specific inflammatory group (0.58 ng/ml) and neoplastic diseases group (0.34 ng/ml). The serum PCT level was positively correlated with serum levels of C-reactive protein (rho=0.62), soluble interleukin-2 receptor (sIL-2R; rho=0.69), and ferritin, the plasma level of D-dimer, and white blood cell count, and negatively correlated with the serum albumin level (rho=−0.52), hemoglobin concentration, and platelet count. The serum PCT level showed a stronger positive correlation with the serum sIL-2R level than the other biomarkers. The results suggest that an increased PCT level may indicate not only an infectious state but also a non-bacterial inflammatory condition in the diagnostic process in general practice. |
| キーワード | bacterial infection inflammation malignant lymphoma procalcitonin soluble interleukin-2 receptor |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2021-06 |
| 巻 | 75巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 299 |
| 終了ページ | 306 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2021 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 34176933 |
| Web of Science KeyUT | 000667147700005 |
| NAID | 120007089836 |